Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : OPHN1_HUMAN

For an explanation of this page, click here

OPHN1_HUMAN
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OPHN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	161
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
θ value	0 (rank : 2)	NC score	0.992647 (rank : 2)
Query Neighborhood Hits	161	Target Neighborhood Hits	174	Shared Neighborhood Hits	119
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG26_HUMAN
θ value	1.19313e-177 (rank : 3)	NC score	0.908646 (rank : 3)
Query Neighborhood Hits	161	Target Neighborhood Hits	281	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

CHIO_MOUSE
θ value	2.68423e-28 (rank : 4)	NC score	0.761128 (rank : 12)
Query Neighborhood Hits	161	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_HUMAN
θ value	5.97985e-28 (rank : 5)	NC score	0.730292 (rank : 15)
Query Neighborhood Hits	161	Target Neighborhood Hits	220	Shared Neighborhood Hits	62
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIN_MOUSE
θ value	5.06226e-27 (rank : 6)	NC score	0.729528 (rank : 16)
Query Neighborhood Hits	161	Target Neighborhood Hits	229	Shared Neighborhood Hits	63
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
θ value	8.63488e-27 (rank : 7)	NC score	0.728074 (rank : 17)
Query Neighborhood Hits	161	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG12_HUMAN
θ value	8.08199e-25 (rank : 8)	NC score	0.779425 (rank : 5)
Query Neighborhood Hits	161	Target Neighborhood Hits	190	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	1.80048e-24 (rank : 9)	NC score	0.777918 (rank : 6)
Query Neighborhood Hits	161	Target Neighborhood Hits	204	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

GRLF1_HUMAN
θ value	5.79196e-23 (rank : 10)	NC score	0.764751 (rank : 11)
Query Neighborhood Hits	161	Target Neighborhood Hits	167	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG09_HUMAN
θ value	8.36355e-22 (rank : 11)	NC score	0.807734 (rank : 4)
Query Neighborhood Hits	161	Target Neighborhood Hits	186	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

GMIP_MOUSE
θ value	2.27762e-19 (rank : 12)	NC score	0.772941 (rank : 8)
Query Neighborhood Hits	161	Target Neighborhood Hits	202	Shared Neighborhood Hits	70
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CENB5_HUMAN
θ value	3.88503e-19 (rank : 13)	NC score	0.273263 (rank : 68)
Query Neighborhood Hits	161	Target Neighborhood Hits	395	Shared Neighborhood Hits	23
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

RHG05_HUMAN
θ value	3.88503e-19 (rank : 14)	NC score	0.727278 (rank : 18)
Query Neighborhood Hits	161	Target Neighborhood Hits	158	Shared Neighborhood Hits	70
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
θ value	5.07402e-19 (rank : 15)	NC score	0.730864 (rank : 14)
Query Neighborhood Hits	161	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

FNBP2_HUMAN
θ value	6.62687e-19 (rank : 16)	NC score	0.661482 (rank : 36)
Query Neighborhood Hits	161	Target Neighborhood Hits	432	Shared Neighborhood Hits	91
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

GMIP_HUMAN
θ value	1.13037e-18 (rank : 17)	NC score	0.764935 (rank : 10)
Query Neighborhood Hits	161	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

TCGAP_HUMAN
θ value	1.13037e-18 (rank : 18)	NC score	0.646828 (rank : 39)
Query Neighborhood Hits	161	Target Neighborhood Hits	872	Shared Neighborhood Hits	81
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RGAP1_HUMAN
θ value	1.47631e-18 (rank : 19)	NC score	0.773101 (rank : 7)
Query Neighborhood Hits	161	Target Neighborhood Hits	189	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

TCGAP_MOUSE
θ value	1.47631e-18 (rank : 20)	NC score	0.725903 (rank : 20)
Query Neighborhood Hits	161	Target Neighborhood Hits	409	Shared Neighborhood Hits	70
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RGAP1_MOUSE
θ value	2.13179e-17 (rank : 21)	NC score	0.770944 (rank : 9)
Query Neighborhood Hits	161	Target Neighborhood Hits	185	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

SRGP1_HUMAN
θ value	2.7842e-17 (rank : 22)	NC score	0.662729 (rank : 35)
Query Neighborhood Hits	161	Target Neighborhood Hits	390	Shared Neighborhood Hits	82
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRGP2_HUMAN
θ value	3.63628e-17 (rank : 23)	NC score	0.671190 (rank : 31)
Query Neighborhood Hits	161	Target Neighborhood Hits	331	Shared Neighborhood Hits	75
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

MYO9B_HUMAN
θ value	1.058e-16 (rank : 24)	NC score	0.399154 (rank : 58)
Query Neighborhood Hits	161	Target Neighborhood Hits	641	Shared Neighborhood Hits	84
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

SRGP2_MOUSE
θ value	1.38178e-16 (rank : 25)	NC score	0.664330 (rank : 34)
Query Neighborhood Hits	161	Target Neighborhood Hits	324	Shared Neighborhood Hits	77
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

MYO9B_MOUSE
θ value	1.80466e-16 (rank : 26)	NC score	0.404125 (rank : 57)
Query Neighborhood Hits	161	Target Neighborhood Hits	311	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RHG01_HUMAN
θ value	4.02038e-16 (rank : 27)	NC score	0.719746 (rank : 21)
Query Neighborhood Hits	161	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

CENB2_HUMAN
θ value	5.25075e-16 (rank : 28)	NC score	0.275833 (rank : 67)
Query Neighborhood Hits	161	Target Neighborhood Hits	425	Shared Neighborhood Hits	27
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

ABR_HUMAN
θ value	6.85773e-16 (rank : 29)	NC score	0.679552 (rank : 29)
Query Neighborhood Hits	161	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG04_HUMAN
θ value	3.40345e-15 (rank : 30)	NC score	0.679704 (rank : 28)
Query Neighborhood Hits	161	Target Neighborhood Hits	307	Shared Neighborhood Hits	77
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

DP13A_HUMAN
θ value	5.8054e-15 (rank : 31)	NC score	0.366844 (rank : 59)
Query Neighborhood Hits	161	Target Neighborhood Hits	107	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

BCR_HUMAN
θ value	2.20605e-14 (rank : 32)	NC score	0.667982 (rank : 33)
Query Neighborhood Hits	161	Target Neighborhood Hits	204	Shared Neighborhood Hits	65
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

DP13A_MOUSE
θ value	3.76295e-14 (rank : 33)	NC score	0.363994 (rank : 61)
Query Neighborhood Hits	161	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

3BP1_HUMAN
θ value	6.41864e-14 (rank : 34)	NC score	0.726629 (rank : 19)
Query Neighborhood Hits	161	Target Neighborhood Hits	376	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CEND2_HUMAN
θ value	4.16044e-13 (rank : 35)	NC score	0.636157 (rank : 40)
Query Neighborhood Hits	161	Target Neighborhood Hits	166	Shared Neighborhood Hits	66
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CENB1_HUMAN
θ value	7.09661e-13 (rank : 36)	NC score	0.257253 (rank : 69)
Query Neighborhood Hits	161	Target Neighborhood Hits	383	Shared Neighborhood Hits	22
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

RHG25_MOUSE
θ value	1.58096e-12 (rank : 37)	NC score	0.668552 (rank : 32)
Query Neighborhood Hits	161	Target Neighborhood Hits	492	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

3BP1_MOUSE
θ value	1.02475e-11 (rank : 38)	NC score	0.738116 (rank : 13)
Query Neighborhood Hits	161	Target Neighborhood Hits	238	Shared Neighborhood Hits	68
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RBP1_MOUSE
θ value	1.02475e-11 (rank : 39)	NC score	0.674691 (rank : 30)
Query Neighborhood Hits	161	Target Neighborhood Hits	493	Shared Neighborhood Hits	92
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_HUMAN
θ value	2.28291e-11 (rank : 40)	NC score	0.659488 (rank : 37)
Query Neighborhood Hits	161	Target Neighborhood Hits	521	Shared Neighborhood Hits	99
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG08_HUMAN
θ value	3.89403e-11 (rank : 41)	NC score	0.694103 (rank : 27)
Query Neighborhood Hits	161	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_MOUSE
θ value	3.89403e-11 (rank : 42)	NC score	0.697704 (rank : 25)
Query Neighborhood Hits	161	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG07_MOUSE
θ value	8.67504e-11 (rank : 43)	NC score	0.618980 (rank : 42)
Query Neighborhood Hits	161	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG25_HUMAN
θ value	8.67504e-11 (rank : 44)	NC score	0.654019 (rank : 38)
Query Neighborhood Hits	161	Target Neighborhood Hits	550	Shared Neighborhood Hits	96
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CEND3_MOUSE
θ value	1.133e-10 (rank : 45)	NC score	0.590799 (rank : 46)
Query Neighborhood Hits	161	Target Neighborhood Hits	228	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

RHG07_HUMAN
θ value	1.133e-10 (rank : 46)	NC score	0.614349 (rank : 44)
Query Neighborhood Hits	161	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CEND3_HUMAN
θ value	1.9326e-10 (rank : 47)	NC score	0.582512 (rank : 48)
Query Neighborhood Hits	161	Target Neighborhood Hits	275	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

RHG18_HUMAN
θ value	1.9326e-10 (rank : 48)	NC score	0.708284 (rank : 24)
Query Neighborhood Hits	161	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

DP13B_MOUSE
θ value	2.52405e-10 (rank : 49)	NC score	0.342568 (rank : 63)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

RHG06_HUMAN
θ value	4.30538e-10 (rank : 50)	NC score	0.717573 (rank : 22)
Query Neighborhood Hits	161	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CE005_HUMAN
θ value	9.59137e-10 (rank : 51)	NC score	0.591701 (rank : 45)
Query Neighborhood Hits	161	Target Neighborhood Hits	213	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
θ value	9.59137e-10 (rank : 52)	NC score	0.588493 (rank : 47)
Query Neighborhood Hits	161	Target Neighborhood Hits	238	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RHG06_MOUSE
θ value	1.25267e-09 (rank : 53)	NC score	0.715663 (rank : 23)
Query Neighborhood Hits	161	Target Neighborhood Hits	105	Shared Neighborhood Hits	63
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CEND1_MOUSE
θ value	2.13673e-09 (rank : 54)	NC score	0.548463 (rank : 53)
Query Neighborhood Hits	161	Target Neighborhood Hits	260	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

RHG18_MOUSE
θ value	2.79066e-09 (rank : 55)	NC score	0.696348 (rank : 26)
Query Neighborhood Hits	161	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

CEND1_HUMAN
θ value	8.11959e-09 (rank : 56)	NC score	0.527213 (rank : 54)
Query Neighborhood Hits	161	Target Neighborhood Hits	284	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

DP13B_HUMAN
θ value	8.11959e-09 (rank : 57)	NC score	0.330630 (rank : 64)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

STA13_HUMAN
θ value	3.08544e-08 (rank : 58)	NC score	0.571896 (rank : 49)
Query Neighborhood Hits	161	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
θ value	1.99992e-07 (rank : 59)	NC score	0.560349 (rank : 52)
Query Neighborhood Hits	161	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

STAR8_HUMAN
θ value	9.92553e-07 (rank : 60)	NC score	0.564686 (rank : 51)
Query Neighborhood Hits	161	Target Neighborhood Hits	216	Shared Neighborhood Hits	62
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_MOUSE
θ value	2.21117e-06 (rank : 61)	NC score	0.569354 (rank : 50)
Query Neighborhood Hits	161	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

TAGAP_HUMAN
θ value	2.21117e-06 (rank : 62)	NC score	0.619819 (rank : 41)
Query Neighborhood Hits	161	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

DDEF2_HUMAN
θ value	6.43352e-06 (rank : 63)	NC score	0.194994 (rank : 70)
Query Neighborhood Hits	161	Target Neighborhood Hits	599	Shared Neighborhood Hits	34
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

P85A_HUMAN
θ value	6.43352e-06 (rank : 64)	NC score	0.366182 (rank : 60)
Query Neighborhood Hits	161	Target Neighborhood Hits	479	Shared Neighborhood Hits	84
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

K1688_MOUSE
θ value	1.09739e-05 (rank : 65)	NC score	0.501570 (rank : 55)
Query Neighborhood Hits	161	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

DDEF2_MOUSE
θ value	1.87187e-05 (rank : 66)	NC score	0.192003 (rank : 71)
Query Neighborhood Hits	161	Target Neighborhood Hits	625	Shared Neighborhood Hits	33
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

P85A_MOUSE
θ value	1.87187e-05 (rank : 67)	NC score	0.359433 (rank : 62)
Query Neighborhood Hits	161	Target Neighborhood Hits	435	Shared Neighborhood Hits	80
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

K1688_HUMAN
θ value	2.44474e-05 (rank : 68)	NC score	0.487876 (rank : 56)
Query Neighborhood Hits	161	Target Neighborhood Hits	217	Shared Neighborhood Hits	63
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

TAGAP_MOUSE
θ value	3.19293e-05 (rank : 69)	NC score	0.617487 (rank : 43)
Query Neighborhood Hits	161	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

DDEF1_MOUSE
θ value	0.00020696 (rank : 70)	NC score	0.182140 (rank : 72)
Query Neighborhood Hits	161	Target Neighborhood Hits	592	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

CT2NL_HUMAN
θ value	0.00390308 (rank : 71)	NC score	0.061290 (rank : 128)
Query Neighborhood Hits	161	Target Neighborhood Hits	1059	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

OCRL_HUMAN
θ value	0.0113563 (rank : 72)	NC score	0.286167 (rank : 65)
Query Neighborhood Hits	161	Target Neighborhood Hits	77	Shared Neighborhood Hits	52
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

RPB5_HUMAN
θ value	0.0961366 (rank : 73)	NC score	0.084656 (rank : 90)
Query Neighborhood Hits	161	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P19388, O43380, Q6PIH5, Q9BT06	Gene names	POLR2E
Domain Architecture
Description	DNA-directed RNA polymerase II 23 kDa polypeptide (EC 2.7.7.6) (RPB25) (RPB5) (RPABC1) (XAP4).

RPB5_MOUSE
θ value	0.0961366 (rank : 74)	NC score	0.084146 (rank : 92)
Query Neighborhood Hits	161	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UW8	Gene names	Polr2e
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase II 23 kDa polypeptide (EC 2.7.7.6) (RPB25) (RPB5) (RPABC1).

MYO5A_MOUSE
θ value	0.125558 (rank : 75)	NC score	0.054004 (rank : 161)
Query Neighborhood Hits	161	Target Neighborhood Hits	1117	Shared Neighborhood Hits	56
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

LRC45_HUMAN
θ value	0.163984 (rank : 76)	NC score	0.041411 (rank : 192)
Query Neighborhood Hits	161	Target Neighborhood Hits	933	Shared Neighborhood Hits	55
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

MY18A_MOUSE
θ value	0.163984 (rank : 77)	NC score	0.056040 (rank : 149)
Query Neighborhood Hits	161	Target Neighborhood Hits	1989	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RAD50_HUMAN
θ value	0.163984 (rank : 78)	NC score	0.048819 (rank : 179)
Query Neighborhood Hits	161	Target Neighborhood Hits	1317	Shared Neighborhood Hits	66
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

TXLNB_HUMAN
θ value	0.163984 (rank : 79)	NC score	0.042275 (rank : 191)
Query Neighborhood Hits	161	Target Neighborhood Hits	912	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

BICD1_MOUSE
θ value	0.21417 (rank : 80)	NC score	0.044799 (rank : 185)
Query Neighborhood Hits	161	Target Neighborhood Hits	837	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

SYCP1_HUMAN
θ value	0.21417 (rank : 81)	NC score	0.044426 (rank : 186)
Query Neighborhood Hits	161	Target Neighborhood Hits	1313	Shared Neighborhood Hits	66
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CYTSA_HUMAN
θ value	0.279714 (rank : 82)	NC score	0.040745 (rank : 196)
Query Neighborhood Hits	161	Target Neighborhood Hits	1138	Shared Neighborhood Hits	63
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

MY18A_HUMAN
θ value	0.279714 (rank : 83)	NC score	0.055060 (rank : 156)
Query Neighborhood Hits	161	Target Neighborhood Hits	1929	Shared Neighborhood Hits	79
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CYTSA_MOUSE
θ value	0.365318 (rank : 84)	NC score	0.041302 (rank : 194)
Query Neighborhood Hits	161	Target Neighborhood Hits	1104	Shared Neighborhood Hits	63
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

EP400_MOUSE
θ value	0.365318 (rank : 85)	NC score	0.029558 (rank : 207)
Query Neighborhood Hits	161	Target Neighborhood Hits	592	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

FER_HUMAN
θ value	0.365318 (rank : 86)	NC score	0.015324 (rank : 233)
Query Neighborhood Hits	161	Target Neighborhood Hits	1278	Shared Neighborhood Hits	52
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

MIPO1_HUMAN
θ value	0.365318 (rank : 87)	NC score	0.047332 (rank : 182)
Query Neighborhood Hits	161	Target Neighborhood Hits	486	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

SYNE1_HUMAN
θ value	0.365318 (rank : 88)	NC score	0.035662 (rank : 201)
Query Neighborhood Hits	161	Target Neighborhood Hits	1484	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ANGP2_HUMAN
θ value	0.47712 (rank : 89)	NC score	0.023230 (rank : 220)
Query Neighborhood Hits	161	Target Neighborhood Hits	400	Shared Neighborhood Hits	38
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

OGFR_HUMAN
θ value	0.47712 (rank : 90)	NC score	0.022567 (rank : 222)
Query Neighborhood Hits	161	Target Neighborhood Hits	1582	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CE290_HUMAN
θ value	0.62314 (rank : 91)	NC score	0.043320 (rank : 189)
Query Neighborhood Hits	161	Target Neighborhood Hits	1553	Shared Neighborhood Hits	68
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

MYO5A_HUMAN
θ value	0.62314 (rank : 92)	NC score	0.052787 (rank : 164)
Query Neighborhood Hits	161	Target Neighborhood Hits	1092	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

NEBU_HUMAN
θ value	0.62314 (rank : 93)	NC score	0.047162 (rank : 183)
Query Neighborhood Hits	161	Target Neighborhood Hits	420	Shared Neighborhood Hits	27
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

SH3G2_MOUSE
θ value	0.62314 (rank : 94)	NC score	0.064980 (rank : 114)
Query Neighborhood Hits	161	Target Neighborhood Hits	319	Shared Neighborhood Hits	27
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

BRD4_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.023559 (rank : 219)
Query Neighborhood Hits	161	Target Neighborhood Hits	851	Shared Neighborhood Hits	44
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CCD39_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.034749 (rank : 204)
Query Neighborhood Hits	161	Target Neighborhood Hits	868	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CP135_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.037282 (rank : 199)
Query Neighborhood Hits	161	Target Neighborhood Hits	1290	Shared Neighborhood Hits	64
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

K1219_HUMAN
θ value	0.813845 (rank : 98)	NC score	0.032324 (rank : 205)
Query Neighborhood Hits	161	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

RAD50_MOUSE
θ value	0.813845 (rank : 99)	NC score	0.049703 (rank : 178)
Query Neighborhood Hits	161	Target Neighborhood Hits	1366	Shared Neighborhood Hits	69
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SH3G2_HUMAN
θ value	0.813845 (rank : 100)	NC score	0.061747 (rank : 125)
Query Neighborhood Hits	161	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

BICD1_HUMAN
θ value	1.06291 (rank : 101)	NC score	0.041202 (rank : 195)
Query Neighborhood Hits	161	Target Neighborhood Hits	844	Shared Neighborhood Hits	59
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

KIF4A_HUMAN
θ value	1.06291 (rank : 102)	NC score	0.026275 (rank : 215)
Query Neighborhood Hits	161	Target Neighborhood Hits	1159	Shared Neighborhood Hits	64
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

LUZP1_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.042389 (rank : 190)
Query Neighborhood Hits	161	Target Neighborhood Hits	739	Shared Neighborhood Hits	49
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

CP250_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.038953 (rank : 198)
Query Neighborhood Hits	161	Target Neighborhood Hits	1805	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CR034_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.046098 (rank : 184)
Query Neighborhood Hits	161	Target Neighborhood Hits	643	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CTRO_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.016178 (rank : 230)
Query Neighborhood Hits	161	Target Neighborhood Hits	2092	Shared Neighborhood Hits	67
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GEMI5_MOUSE
θ value	1.38821 (rank : 107)	NC score	0.013843 (rank : 236)
Query Neighborhood Hits	161	Target Neighborhood Hits	424	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

MAST4_HUMAN
θ value	1.38821 (rank : 108)	NC score	0.002172 (rank : 253)
Query Neighborhood Hits	161	Target Neighborhood Hits	1804	Shared Neighborhood Hits	38
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

CCHCR_MOUSE
θ value	1.81305 (rank : 109)	NC score	0.035196 (rank : 202)
Query Neighborhood Hits	161	Target Neighborhood Hits	932	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CTRO_MOUSE
θ value	1.81305 (rank : 110)	NC score	0.019911 (rank : 227)
Query Neighborhood Hits	161	Target Neighborhood Hits	2344	Shared Neighborhood Hits	75
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ITSN2_MOUSE
θ value	1.81305 (rank : 111)	NC score	0.061093 (rank : 131)
Query Neighborhood Hits	161	Target Neighborhood Hits	1371	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

K1219_MOUSE
θ value	1.81305 (rank : 112)	NC score	0.026902 (rank : 214)
Query Neighborhood Hits	161	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

CH013_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.024676 (rank : 218)
Query Neighborhood Hits	161	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KS9, Q8N3M3, Q9NSR0	Gene names	C8orf13
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C8orf13.

CRSP7_HUMAN
θ value	2.36792 (rank : 114)	NC score	0.016123 (rank : 231)
Query Neighborhood Hits	161	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

MACF1_HUMAN
θ value	2.36792 (rank : 115)	NC score	0.025319 (rank : 217)
Query Neighborhood Hits	161	Target Neighborhood Hits	1341	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

RL1D1_HUMAN
θ value	2.36792 (rank : 116)	NC score	0.020161 (rank : 225)
Query Neighborhood Hits	161	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

ATX2_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.019930 (rank : 226)
Query Neighborhood Hits	161	Target Neighborhood Hits	375	Shared Neighborhood Hits	11
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CCD46_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.041367 (rank : 193)
Query Neighborhood Hits	161	Target Neighborhood Hits	1405	Shared Neighborhood Hits	72
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CENPF_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.044195 (rank : 187)
Query Neighborhood Hits	161	Target Neighborhood Hits	1932	Shared Neighborhood Hits	83
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

GCC2_MOUSE
θ value	3.0926 (rank : 120)	NC score	0.039453 (rank : 197)
Query Neighborhood Hits	161	Target Neighborhood Hits	1619	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GP153_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.017368 (rank : 229)
Query Neighborhood Hits	161	Target Neighborhood Hits	332	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NV75, Q5TGR5, Q6AHW8, Q86SP8	Gene names	GPR153, PGR1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

HAP1_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.036821 (rank : 200)
Query Neighborhood Hits	161	Target Neighborhood Hits	606	Shared Neighborhood Hits	49
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

LHX1_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.001836 (rank : 254)
Query Neighborhood Hits	161	Target Neighborhood Hits	453	Shared Neighborhood Hits	4
SwissProt Accessions	P48742, Q3MIW0	Gene names	LHX1, LIM1
Domain Architecture
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

MLL3_HUMAN
θ value	3.0926 (rank : 124)	NC score	0.010735 (rank : 241)
Query Neighborhood Hits	161	Target Neighborhood Hits	1644	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYH11_MOUSE
θ value	3.0926 (rank : 125)	NC score	0.048488 (rank : 180)
Query Neighborhood Hits	161	Target Neighborhood Hits	1777	Shared Neighborhood Hits	74
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

SEM4C_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.002899 (rank : 252)
Query Neighborhood Hits	161	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

SYN2_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.011138 (rank : 240)
Query Neighborhood Hits	161	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

ANR11_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.028500 (rank : 211)
Query Neighborhood Hits	161	Target Neighborhood Hits	1289	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ATX2_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.019249 (rank : 228)
Query Neighborhood Hits	161	Target Neighborhood Hits	445	Shared Neighborhood Hits	14
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

BRD4_MOUSE
θ value	4.03905 (rank : 130)	NC score	0.020973 (rank : 224)
Query Neighborhood Hits	161	Target Neighborhood Hits	845	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CF060_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.028481 (rank : 212)
Query Neighborhood Hits	161	Target Neighborhood Hits	1270	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

MYH11_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.047765 (rank : 181)
Query Neighborhood Hits	161	Target Neighborhood Hits	1806	Shared Neighborhood Hits	74
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RADI_MOUSE
θ value	4.03905 (rank : 133)	NC score	0.023103 (rank : 221)
Query Neighborhood Hits	161	Target Neighborhood Hits	773	Shared Neighborhood Hits	51
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

RUFY2_MOUSE
θ value	4.03905 (rank : 134)	NC score	0.028883 (rank : 208)
Query Neighborhood Hits	161	Target Neighborhood Hits	820	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

BPA1_MOUSE
θ value	5.27518 (rank : 135)	NC score	0.027610 (rank : 213)
Query Neighborhood Hits	161	Target Neighborhood Hits	1477	Shared Neighborhood Hits	59
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BXDC2_MOUSE
θ value	5.27518 (rank : 136)	NC score	0.012327 (rank : 239)
Query Neighborhood Hits	161	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCA5, Q91YS6	Gene names	Bxdc2, Brix
Domain Architecture
Description	Brix domain-containing protein 2 (Ribosome biogenesis protein Brix).

EXOC3_MOUSE
θ value	5.27518 (rank : 137)	NC score	0.014301 (rank : 234)
Query Neighborhood Hits	161	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q6KAR6	Gene names	Exoc3, Sec6l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

LHX1_MOUSE
θ value	5.27518 (rank : 138)	NC score	0.001192 (rank : 255)
Query Neighborhood Hits	161	Target Neighborhood Hits	453	Shared Neighborhood Hits	4
SwissProt Accessions	P63006, P36199	Gene names	Lhx1, Lim-1, Lim1
Domain Architecture	No domain graphic available
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

LUZP1_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.034979 (rank : 203)
Query Neighborhood Hits	161	Target Neighborhood Hits	940	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MACF1_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.028774 (rank : 209)
Query Neighborhood Hits	161	Target Neighborhood Hits	1313	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

NEST_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.021726 (rank : 223)
Query Neighborhood Hits	161	Target Neighborhood Hits	1305	Shared Neighborhood Hits	59
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

BAP1_MOUSE
θ value	6.88961 (rank : 142)	NC score	0.008246 (rank : 249)
Query Neighborhood Hits	161	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

CRSP2_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.013608 (rank : 237)
Query Neighborhood Hits	161	Target Neighborhood Hits	380	Shared Neighborhood Hits	10
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

EVPL_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.029742 (rank : 206)
Query Neighborhood Hits	161	Target Neighborhood Hits	895	Shared Neighborhood Hits	53
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

I5P2_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.278473 (rank : 66)
Query Neighborhood Hits	161	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

JADE2_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.015639 (rank : 232)
Query Neighborhood Hits	161	Target Neighborhood Hits	560	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

PTN23_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.009274 (rank : 248)
Query Neighborhood Hits	161	Target Neighborhood Hits	726	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SM1L2_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.028656 (rank : 210)
Query Neighborhood Hits	161	Target Neighborhood Hits	1019	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

BAZ1B_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.009821 (rank : 244)
Query Neighborhood Hits	161	Target Neighborhood Hits	701	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

CCD46_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.044096 (rank : 188)
Query Neighborhood Hits	161	Target Neighborhood Hits	1430	Shared Neighborhood Hits	73
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CHCH6_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.013899 (rank : 235)
Query Neighborhood Hits	161	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q91VN4	Gene names	Chchd6
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 6.

COG7_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.026239 (rank : 216)
Query Neighborhood Hits	161	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	P83436, Q6UWU7	Gene names	COG7
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 7.

DIAP3_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.009661 (rank : 246)
Query Neighborhood Hits	161	Target Neighborhood Hits	221	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

EPN1_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.010370 (rank : 243)
Query Neighborhood Hits	161	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

HS74L_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.004231 (rank : 250)
Query Neighborhood Hits	161	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

NUCB2_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.013406 (rank : 238)
Query Neighborhood Hits	161	Target Neighborhood Hits	321	Shared Neighborhood Hits	30
SwissProt Accessions	P80303, Q8NFT5	Gene names	NUCB2, NEFA
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4).

PPRB_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.009409 (rank : 247)
Query Neighborhood Hits	161	Target Neighborhood Hits	311	Shared Neighborhood Hits	12
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SEP11_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.009804 (rank : 245)
Query Neighborhood Hits	161	Target Neighborhood Hits	296	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NVA2, Q7L4N1	Gene names	SEPT11
Domain Architecture	No domain graphic available
Description	Septin-11.

SMRC1_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.010389 (rank : 242)
Query Neighborhood Hits	161	Target Neighborhood Hits	459	Shared Neighborhood Hits	22
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

STK10_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.003850 (rank : 251)
Query Neighborhood Hits	161	Target Neighborhood Hits	1921	Shared Neighborhood Hits	62
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

UTP15_MOUSE
θ value	8.99809 (rank : 161)	NC score	-0.000688 (rank : 256)
Query Neighborhood Hits	161	Target Neighborhood Hits	309	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).

ABI1_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.054675 (rank : 158)
Query Neighborhood Hits	161	Target Neighborhood Hits	246	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI2_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.062314 (rank : 122)
Query Neighborhood Hits	161	Target Neighborhood Hits	350	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.061783 (rank : 123)
Query Neighborhood Hits	161	Target Neighborhood Hits	266	Shared Neighborhood Hits	19
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

ARFG1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.100512 (rank : 86)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG1_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.104994 (rank : 82)
Query Neighborhood Hits	161	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.103068 (rank : 83)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.102542 (rank : 85)
Query Neighborhood Hits	161	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARHG7_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.052066 (rank : 166)
Query Neighborhood Hits	161	Target Neighborhood Hits	396	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

CD2AP_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.065861 (rank : 112)
Query Neighborhood Hits	161	Target Neighborhood Hits	315	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

CD2AP_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.058249 (rank : 141)
Query Neighborhood Hits	161	Target Neighborhood Hits	336	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

CENA1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.109289 (rank : 79)
Query Neighborhood Hits	161	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.107706 (rank : 80)
Query Neighborhood Hits	161	Target Neighborhood Hits	83	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.103002 (rank : 84)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CENG1_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.091278 (rank : 88)
Query Neighborhood Hits	161	Target Neighborhood Hits	544	Shared Neighborhood Hits	18
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG1_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.093455 (rank : 87)
Query Neighborhood Hits	161	Target Neighborhood Hits	531	Shared Neighborhood Hits	20
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG2_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.078481 (rank : 97)
Query Neighborhood Hits	161	Target Neighborhood Hits	471	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG2_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.078640 (rank : 95)
Query Neighborhood Hits	161	Target Neighborhood Hits	463	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENG3_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.084627 (rank : 91)
Query Neighborhood Hits	161	Target Neighborhood Hits	455	Shared Neighborhood Hits	13
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.085790 (rank : 89)
Query Neighborhood Hits	161	Target Neighborhood Hits	467	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CIP4_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.069507 (rank : 103)
Query Neighborhood Hits	161	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CRKL_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.053702 (rank : 162)
Query Neighborhood Hits	161	Target Neighborhood Hits	313	Shared Neighborhood Hits	22
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

DAPP1_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.067395 (rank : 106)
Query Neighborhood Hits	161	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.071295 (rank : 101)
Query Neighborhood Hits	161	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DDFL1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.162271 (rank : 73)
Query Neighborhood Hits	161	Target Neighborhood Hits	353	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.143337 (rank : 74)
Query Neighborhood Hits	161	Target Neighborhood Hits	324	Shared Neighborhood Hits	17
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DGKH_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.055423 (rank : 152)
Query Neighborhood Hits	161	Target Neighborhood Hits	255	Shared Neighborhood Hits	21
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DNMBP_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.055287 (rank : 153)
Query Neighborhood Hits	161	Target Neighborhood Hits	413	Shared Neighborhood Hits	30
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

DNMBP_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.052165 (rank : 165)
Query Neighborhood Hits	161	Target Neighborhood Hits	435	Shared Neighborhood Hits	33
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

FA13A_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.060330 (rank : 134)
Query Neighborhood Hits	161	Target Neighborhood Hits	102	Shared Neighborhood Hits	13
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.059808 (rank : 136)
Query Neighborhood Hits	161	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

GIT1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.077632 (rank : 98)
Query Neighborhood Hits	161	Target Neighborhood Hits	336	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.075778 (rank : 99)
Query Neighborhood Hits	161	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT2_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.079749 (rank : 94)
Query Neighborhood Hits	161	Target Neighborhood Hits	381	Shared Neighborhood Hits	24
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GIT2_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.078515 (rank : 96)
Query Neighborhood Hits	161	Target Neighborhood Hits	323	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

GRAP2_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.058814 (rank : 137)
Query Neighborhood Hits	161	Target Neighborhood Hits	304	Shared Neighborhood Hits	21
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.056209 (rank : 147)
Query Neighborhood Hits	161	Target Neighborhood Hits	297	Shared Neighborhood Hits	22
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

GRAP_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.067132 (rank : 108)
Query Neighborhood Hits	161	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.064817 (rank : 115)
Query Neighborhood Hits	161	Target Neighborhood Hits	309	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.067179 (rank : 107)
Query Neighborhood Hits	161	Target Neighborhood Hits	310	Shared Neighborhood Hits	22
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.067098 (rank : 109)
Query Neighborhood Hits	161	Target Neighborhood Hits	312	Shared Neighborhood Hits	22
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

GRP3_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.082169 (rank : 93)
Query Neighborhood Hits	161	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

HCLS1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.060291 (rank : 135)
Query Neighborhood Hits	161	Target Neighborhood Hits	358	Shared Neighborhood Hits	22
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

HCLS1_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.058781 (rank : 138)
Query Neighborhood Hits	161	Target Neighborhood Hits	329	Shared Neighborhood Hits	25
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

HRBL_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.056160 (rank : 148)
Query Neighborhood Hits	161	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

HRBL_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.054437 (rank : 159)
Query Neighborhood Hits	161	Target Neighborhood Hits	269	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

ITSN1_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.063961 (rank : 117)
Query Neighborhood Hits	161	Target Neighborhood Hits	1757	Shared Neighborhood Hits	82
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.062459 (rank : 121)
Query Neighborhood Hits	161	Target Neighborhood Hits	1669	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.061234 (rank : 129)
Query Neighborhood Hits	161	Target Neighborhood Hits	1173	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

MYO10_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.063140 (rank : 119)
Query Neighborhood Hits	161	Target Neighborhood Hits	920	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MYO1E_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.057642 (rank : 143)
Query Neighborhood Hits	161	Target Neighborhood Hits	293	Shared Neighborhood Hits	24
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYO1F_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.058124 (rank : 142)
Query Neighborhood Hits	161	Target Neighborhood Hits	275	Shared Neighborhood Hits	25
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.058392 (rank : 140)
Query Neighborhood Hits	161	Target Neighborhood Hits	262	Shared Neighborhood Hits	23
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

MYO5C_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.050772 (rank : 172)
Query Neighborhood Hits	161	Target Neighborhood Hits	1206	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NCF2_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.057076 (rank : 145)
Query Neighborhood Hits	161	Target Neighborhood Hits	229	Shared Neighborhood Hits	19
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NCF4_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.061185 (rank : 130)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	13
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCF4_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.066383 (rank : 111)
Query Neighborhood Hits	161	Target Neighborhood Hits	177	Shared Neighborhood Hits	15
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

NCK1_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.057097 (rank : 144)
Query Neighborhood Hits	161	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCK2_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.067936 (rank : 105)
Query Neighborhood Hits	161	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NUPL_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.061687 (rank : 126)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

NUPL_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.061067 (rank : 132)
Query Neighborhood Hits	161	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

P55G_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.057021 (rank : 146)
Query Neighborhood Hits	161	Target Neighborhood Hits	451	Shared Neighborhood Hits	35
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.053576 (rank : 163)
Query Neighborhood Hits	161	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85B_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.106825 (rank : 81)
Query Neighborhood Hits	161	Target Neighborhood Hits	543	Shared Neighborhood Hits	57
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.075574 (rank : 100)
Query Neighborhood Hits	161	Target Neighborhood Hits	519	Shared Neighborhood Hits	53
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PCTL_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.050498 (rank : 174)
Query Neighborhood Hits	161	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

PCTL_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.051085 (rank : 170)
Query Neighborhood Hits	161	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PDZD8_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.058470 (rank : 139)
Query Neighborhood Hits	161	Target Neighborhood Hits	185	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PKHA1_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.070511 (rank : 102)
Query Neighborhood Hits	161	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.065185 (rank : 113)
Query Neighborhood Hits	161	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.050785 (rank : 171)
Query Neighborhood Hits	161	Target Neighborhood Hits	116	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA6_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.055556 (rank : 151)
Query Neighborhood Hits	161	Target Neighborhood Hits	556	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.055182 (rank : 155)
Query Neighborhood Hits	161	Target Neighborhood Hits	591	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PPIP1_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.052025 (rank : 167)
Query Neighborhood Hits	161	Target Neighborhood Hits	389	Shared Neighborhood Hits	39
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SH3G1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.054099 (rank : 160)
Query Neighborhood Hits	161	Target Neighborhood Hits	307	Shared Neighborhood Hits	29
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

SH3G1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.051872 (rank : 168)
Query Neighborhood Hits	161	Target Neighborhood Hits	291	Shared Neighborhood Hits	25
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

SH3K1_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.061758 (rank : 124)
Query Neighborhood Hits	161	Target Neighborhood Hits	341	Shared Neighborhood Hits	25
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3K1_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.066604 (rank : 110)
Query Neighborhood Hits	161	Target Neighborhood Hits	332	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SMAP1_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.109958 (rank : 78)
Query Neighborhood Hits	161	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.111043 (rank : 77)
Query Neighborhood Hits	161	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.111971 (rank : 75)
Query Neighborhood Hits	161	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.111494 (rank : 76)
Query Neighborhood Hits	161	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SRBS1_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.064456 (rank : 116)
Query Neighborhood Hits	161	Target Neighborhood Hits	396	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.061654 (rank : 127)
Query Neighborhood Hits	161	Target Neighborhood Hits	409	Shared Neighborhood Hits	31
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STAC3_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.060781 (rank : 133)
Query Neighborhood Hits	161	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.062713 (rank : 120)
Query Neighborhood Hits	161	Target Neighborhood Hits	232	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.051242 (rank : 169)
Query Neighborhood Hits	161	Target Neighborhood Hits	276	Shared Neighborhood Hits	18
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.055234 (rank : 154)
Query Neighborhood Hits	161	Target Neighborhood Hits	268	Shared Neighborhood Hits	18
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

UN13A_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.050401 (rank : 175)
Query Neighborhood Hits	161	Target Neighborhood Hits	285	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.050748 (rank : 173)
Query Neighborhood Hits	161	Target Neighborhood Hits	217	Shared Neighborhood Hits	16
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

VAV2_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.050222 (rank : 176)
Query Neighborhood Hits	161	Target Neighborhood Hits	453	Shared Neighborhood Hits	27
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.050011 (rank : 177)
Query Neighborhood Hits	161	Target Neighborhood Hits	456	Shared Neighborhood Hits	25
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.055775 (rank : 150)
Query Neighborhood Hits	161	Target Neighborhood Hits	398	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.054786 (rank : 157)
Query Neighborhood Hits	161	Target Neighborhood Hits	404	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VINEX_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.063920 (rank : 118)
Query Neighborhood Hits	161	Target Neighborhood Hits	270	Shared Neighborhood Hits	22
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.068740 (rank : 104)
Query Neighborhood Hits	161	Target Neighborhood Hits	286	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

Hits sorted by NC score

OPHN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	161
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
NC score	0.992647 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	161	Target Neighborhood Hits	174	Shared Neighborhood Hits	119
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG26_HUMAN
NC score	0.908646 (rank : 3)	θ value	1.19313e-177 (rank : 3)
Query Neighborhood Hits	161	Target Neighborhood Hits	281	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG09_HUMAN
NC score	0.807734 (rank : 4)	θ value	8.36355e-22 (rank : 11)
Query Neighborhood Hits	161	Target Neighborhood Hits	186	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_HUMAN
NC score	0.779425 (rank : 5)	θ value	8.08199e-25 (rank : 8)
Query Neighborhood Hits	161	Target Neighborhood Hits	190	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
NC score	0.777918 (rank : 6)	θ value	1.80048e-24 (rank : 9)
Query Neighborhood Hits	161	Target Neighborhood Hits	204	Shared Neighborhood Hits	64
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RGAP1_HUMAN
NC score	0.773101 (rank : 7)	θ value	1.47631e-18 (rank : 19)
Query Neighborhood Hits	161	Target Neighborhood Hits	189	Shared Neighborhood Hits	74
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

GMIP_MOUSE
NC score	0.772941 (rank : 8)	θ value	2.27762e-19 (rank : 12)
Query Neighborhood Hits	161	Target Neighborhood Hits	202	Shared Neighborhood Hits	70
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RGAP1_MOUSE
NC score	0.770944 (rank : 9)	θ value	2.13179e-17 (rank : 21)
Query Neighborhood Hits	161	Target Neighborhood Hits	185	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

GMIP_HUMAN
NC score	0.764935 (rank : 10)	θ value	1.13037e-18 (rank : 17)
Query Neighborhood Hits	161	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GRLF1_HUMAN
NC score	0.764751 (rank : 11)	θ value	5.79196e-23 (rank : 10)
Query Neighborhood Hits	161	Target Neighborhood Hits	167	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

CHIO_MOUSE
NC score	0.761128 (rank : 12)	θ value	2.68423e-28 (rank : 4)
Query Neighborhood Hits	161	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

3BP1_MOUSE
NC score	0.738116 (rank : 13)	θ value	1.02475e-11 (rank : 38)
Query Neighborhood Hits	161	Target Neighborhood Hits	238	Shared Neighborhood Hits	68
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG05_MOUSE
NC score	0.730864 (rank : 14)	θ value	5.07402e-19 (rank : 15)
Query Neighborhood Hits	161	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CHIO_HUMAN
NC score	0.730292 (rank : 15)	θ value	5.97985e-28 (rank : 5)
Query Neighborhood Hits	161	Target Neighborhood Hits	220	Shared Neighborhood Hits	62
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIN_MOUSE
NC score	0.729528 (rank : 16)	θ value	5.06226e-27 (rank : 6)
Query Neighborhood Hits	161	Target Neighborhood Hits	229	Shared Neighborhood Hits	63
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
NC score	0.728074 (rank : 17)	θ value	8.63488e-27 (rank : 7)
Query Neighborhood Hits	161	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG05_HUMAN
NC score	0.727278 (rank : 18)	θ value	3.88503e-19 (rank : 14)
Query Neighborhood Hits	161	Target Neighborhood Hits	158	Shared Neighborhood Hits	70
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

3BP1_HUMAN
NC score	0.726629 (rank : 19)	θ value	6.41864e-14 (rank : 34)
Query Neighborhood Hits	161	Target Neighborhood Hits	376	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

TCGAP_MOUSE
NC score	0.725903 (rank : 20)	θ value	1.47631e-18 (rank : 20)
Query Neighborhood Hits	161	Target Neighborhood Hits	409	Shared Neighborhood Hits	70
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG01_HUMAN
NC score	0.719746 (rank : 21)	θ value	4.02038e-16 (rank : 27)
Query Neighborhood Hits	161	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG06_HUMAN
NC score	0.717573 (rank : 22)	θ value	4.30538e-10 (rank : 50)
Query Neighborhood Hits	161	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.715663 (rank : 23)	θ value	1.25267e-09 (rank : 53)
Query Neighborhood Hits	161	Target Neighborhood Hits	105	Shared Neighborhood Hits	63
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG18_HUMAN
NC score	0.708284 (rank : 24)	θ value	1.9326e-10 (rank : 48)
Query Neighborhood Hits	161	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG08_MOUSE
NC score	0.697704 (rank : 25)	θ value	3.89403e-11 (rank : 42)
Query Neighborhood Hits	161	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG18_MOUSE
NC score	0.696348 (rank : 26)	θ value	2.79066e-09 (rank : 55)
Query Neighborhood Hits	161	Target Neighborhood Hits	110	Shared Neighborhood Hits	62
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG08_HUMAN
NC score	0.694103 (rank : 27)	θ value	3.89403e-11 (rank : 41)
Query Neighborhood Hits	161	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG04_HUMAN
NC score	0.679704 (rank : 28)	θ value	3.40345e-15 (rank : 30)
Query Neighborhood Hits	161	Target Neighborhood Hits	307	Shared Neighborhood Hits	77
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

ABR_HUMAN
NC score	0.679552 (rank : 29)	θ value	6.85773e-16 (rank : 29)
Query Neighborhood Hits	161	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RBP1_MOUSE
NC score	0.674691 (rank : 30)	θ value	1.02475e-11 (rank : 39)
Query Neighborhood Hits	161	Target Neighborhood Hits	493	Shared Neighborhood Hits	92
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SRGP2_HUMAN
NC score	0.671190 (rank : 31)	θ value	3.63628e-17 (rank : 23)
Query Neighborhood Hits	161	Target Neighborhood Hits	331	Shared Neighborhood Hits	75
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG25_MOUSE
NC score	0.668552 (rank : 32)	θ value	1.58096e-12 (rank : 37)
Query Neighborhood Hits	161	Target Neighborhood Hits	492	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

BCR_HUMAN
NC score	0.667982 (rank : 33)	θ value	2.20605e-14 (rank : 32)
Query Neighborhood Hits	161	Target Neighborhood Hits	204	Shared Neighborhood Hits	65
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

SRGP2_MOUSE
NC score	0.664330 (rank : 34)	θ value	1.38178e-16 (rank : 25)
Query Neighborhood Hits	161	Target Neighborhood Hits	324	Shared Neighborhood Hits	77
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRGP1_HUMAN
NC score	0.662729 (rank : 35)	θ value	2.7842e-17 (rank : 22)
Query Neighborhood Hits	161	Target Neighborhood Hits	390	Shared Neighborhood Hits	82
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

FNBP2_HUMAN
NC score	0.661482 (rank : 36)	θ value	6.62687e-19 (rank : 16)
Query Neighborhood Hits	161	Target Neighborhood Hits	432	Shared Neighborhood Hits	91
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RBP1_HUMAN
NC score	0.659488 (rank : 37)	θ value	2.28291e-11 (rank : 40)
Query Neighborhood Hits	161	Target Neighborhood Hits	521	Shared Neighborhood Hits	99
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG25_HUMAN
NC score	0.654019 (rank : 38)	θ value	8.67504e-11 (rank : 44)
Query Neighborhood Hits	161	Target Neighborhood Hits	550	Shared Neighborhood Hits	96
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TCGAP_HUMAN
NC score	0.646828 (rank : 39)	θ value	1.13037e-18 (rank : 18)
Query Neighborhood Hits	161	Target Neighborhood Hits	872	Shared Neighborhood Hits	81
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CEND2_HUMAN
NC score	0.636157 (rank : 40)	θ value	4.16044e-13 (rank : 35)
Query Neighborhood Hits	161	Target Neighborhood Hits	166	Shared Neighborhood Hits	66
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

TAGAP_HUMAN
NC score	0.619819 (rank : 41)	θ value	2.21117e-06 (rank : 62)
Query Neighborhood Hits	161	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG07_MOUSE
NC score	0.618980 (rank : 42)	θ value	8.67504e-11 (rank : 43)
Query Neighborhood Hits	161	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

TAGAP_MOUSE
NC score	0.617487 (rank : 43)	θ value	3.19293e-05 (rank : 69)
Query Neighborhood Hits	161	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG07_HUMAN
NC score	0.614349 (rank : 44)	θ value	1.133e-10 (rank : 46)
Query Neighborhood Hits	161	Target Neighborhood Hits	108	Shared Neighborhood Hits	63
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CE005_HUMAN
NC score	0.591701 (rank : 45)	θ value	9.59137e-10 (rank : 51)
Query Neighborhood Hits	161	Target Neighborhood Hits	213	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CEND3_MOUSE
NC score	0.590799 (rank : 46)	θ value	1.133e-10 (rank : 45)
Query Neighborhood Hits	161	Target Neighborhood Hits	228	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CE005_MOUSE
NC score	0.588493 (rank : 47)	θ value	9.59137e-10 (rank : 52)
Query Neighborhood Hits	161	Target Neighborhood Hits	238	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CEND3_HUMAN
NC score	0.582512 (rank : 48)	θ value	1.9326e-10 (rank : 47)
Query Neighborhood Hits	161	Target Neighborhood Hits	275	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

STA13_HUMAN
NC score	0.571896 (rank : 49)	θ value	3.08544e-08 (rank : 58)
Query Neighborhood Hits	161	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STAR8_MOUSE
NC score	0.569354 (rank : 50)	θ value	2.21117e-06 (rank : 61)
Query Neighborhood Hits	161	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
NC score	0.564686 (rank : 51)	θ value	9.92553e-07 (rank : 60)
Query Neighborhood Hits	161	Target Neighborhood Hits	216	Shared Neighborhood Hits	62
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_MOUSE
NC score	0.560349 (rank : 52)	θ value	1.99992e-07 (rank : 59)
Query Neighborhood Hits	161	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CEND1_MOUSE
NC score	0.548463 (rank : 53)	θ value	2.13673e-09 (rank : 54)
Query Neighborhood Hits	161	Target Neighborhood Hits	260	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
NC score	0.527213 (rank : 54)	θ value	8.11959e-09 (rank : 56)
Query Neighborhood Hits	161	Target Neighborhood Hits	284	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

K1688_MOUSE
NC score	0.501570 (rank : 55)	θ value	1.09739e-05 (rank : 65)
Query Neighborhood Hits	161	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.487876 (rank : 56)	θ value	2.44474e-05 (rank : 68)
Query Neighborhood Hits	161	Target Neighborhood Hits	217	Shared Neighborhood Hits	63
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MYO9B_MOUSE
NC score	0.404125 (rank : 57)	θ value	1.80466e-16 (rank : 26)
Query Neighborhood Hits	161	Target Neighborhood Hits	311	Shared Neighborhood Hits	74
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.399154 (rank : 58)	θ value	1.058e-16 (rank : 24)
Query Neighborhood Hits	161	Target Neighborhood Hits	641	Shared Neighborhood Hits	84
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

DP13A_HUMAN
NC score	0.366844 (rank : 59)	θ value	5.8054e-15 (rank : 31)
Query Neighborhood Hits	161	Target Neighborhood Hits	107	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

P85A_HUMAN
NC score	0.366182 (rank : 60)	θ value	6.43352e-06 (rank : 64)
Query Neighborhood Hits	161	Target Neighborhood Hits	479	Shared Neighborhood Hits	84
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

DP13A_MOUSE
NC score	0.363994 (rank : 61)	θ value	3.76295e-14 (rank : 33)
Query Neighborhood Hits	161	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

P85A_MOUSE
NC score	0.359433 (rank : 62)	θ value	1.87187e-05 (rank : 67)
Query Neighborhood Hits	161	Target Neighborhood Hits	435	Shared Neighborhood Hits	80
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

DP13B_MOUSE
NC score	0.342568 (rank : 63)	θ value	2.52405e-10 (rank : 49)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

DP13B_HUMAN
NC score	0.330630 (rank : 64)	θ value	8.11959e-09 (rank : 57)
Query Neighborhood Hits	161	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

OCRL_HUMAN
NC score	0.286167 (rank : 65)	θ value	0.0113563 (rank : 72)
Query Neighborhood Hits	161	Target Neighborhood Hits	77	Shared Neighborhood Hits	52
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

I5P2_HUMAN
NC score	0.278473 (rank : 66)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	161	Target Neighborhood Hits	86	Shared Neighborhood Hits	52
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

CENB2_HUMAN
NC score	0.275833 (rank : 67)	θ value	5.25075e-16 (rank : 28)
Query Neighborhood Hits	161	Target Neighborhood Hits	425	Shared Neighborhood Hits	27
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
NC score	0.273263 (rank : 68)	θ value	3.88503e-19 (rank : 13)
Query Neighborhood Hits	161	Target Neighborhood Hits	395	Shared Neighborhood Hits	23
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB1_HUMAN
NC score	0.257253 (rank : 69)	θ value	7.09661e-13 (rank : 36)
Query Neighborhood Hits	161	Target Neighborhood Hits	383	Shared Neighborhood Hits	22
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DDEF2_HUMAN
NC score	0.194994 (rank : 70)	θ value	6.43352e-06 (rank : 63)
Query Neighborhood Hits	161	Target Neighborhood Hits	599	Shared Neighborhood Hits	34
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.192003 (rank : 71)	θ value	1.87187e-05 (rank : 66)
Query Neighborhood Hits	161	Target Neighborhood Hits	625	Shared Neighborhood Hits	33
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF1_MOUSE
NC score	0.182140 (rank : 72)	θ value	0.00020696 (rank : 70)
Query Neighborhood Hits	161	Target Neighborhood Hits	592	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDFL1_HUMAN
NC score	0.162271 (rank : 73)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	161	Target Neighborhood Hits	353	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
NC score	0.143337 (rank : 74)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	161	Target Neighborhood Hits	324	Shared Neighborhood Hits	17
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

SMP1L_HUMAN
NC score	0.111971 (rank : 75)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	161	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
NC score	0.111494 (rank : 76)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	161	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMAP1_MOUSE
NC score	0.111043 (rank : 77)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	161	Target Neighborhood Hits	120	Shared Neighborhood Hits	13
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_HUMAN
NC score	0.109958 (rank : 78)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	161	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

CENA1_HUMAN
NC score	0.109289 (rank : 79)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	161	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
NC score	0.107706 (rank : 80)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	161	Target Neighborhood Hits	83	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

P85B_HUMAN
NC score	0.106825 (rank : 81)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	161	Target Neighborhood Hits	543	Shared Neighborhood Hits	57
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

ARFG1_MOUSE
NC score	0.104994 (rank : 82)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	161	Target Neighborhood Hits	51	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG3_HUMAN
NC score	0.103068 (rank : 83)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	161	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

CENA2_MOUSE
NC score	0.103002 (rank : 84)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

ARFG3_MOUSE
NC score	0.102542 (rank : 85)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	161	Target Neighborhood Hits	80	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG1_HUMAN
NC score	0.100512 (rank : 86)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	161	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

CENG1_MOUSE
NC score	0.093455 (rank : 87)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	161	Target Neighborhood Hits	531	Shared Neighborhood Hits	20
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG1_HUMAN
NC score	0.091278 (rank : 88)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	161	Target Neighborhood Hits	544	Shared Neighborhood Hits	18
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG3_MOUSE
NC score	0.085790 (rank : 89)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	161	Target Neighborhood Hits	467	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

RPB5_HUMAN
NC score	0.084656 (rank : 90)	θ value	0.0961366 (rank : 73)
Query Neighborhood Hits	161	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P19388, O43380, Q6PIH5, Q9BT06	Gene names	POLR2E
Domain Architecture
Description	DNA-directed RNA polymerase II 23 kDa polypeptide (EC 2.7.7.6) (RPB25) (RPB5) (RPABC1) (XAP4).

CENG3_HUMAN
NC score	0.084627 (rank : 91)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	161	Target Neighborhood Hits	455	Shared Neighborhood Hits	13
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

RPB5_MOUSE
NC score	0.084146 (rank : 92)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	161	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UW8	Gene names	Polr2e
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase II 23 kDa polypeptide (EC 2.7.7.6) (RPB25) (RPB5) (RPABC1).

GRP3_HUMAN
NC score	0.082169 (rank : 93)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	161	Target Neighborhood Hits	131	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

GIT2_HUMAN
NC score	0.079749 (rank : 94)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	161	Target Neighborhood Hits	381	Shared Neighborhood Hits	24
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

CENG2_MOUSE
NC score	0.078640 (rank : 95)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	161	Target Neighborhood Hits	463	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

GIT2_MOUSE
NC score	0.078515 (rank : 96)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	161	Target Neighborhood Hits	323	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

CENG2_HUMAN
NC score	0.078481 (rank : 97)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	161	Target Neighborhood Hits	471	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

GIT1_HUMAN
NC score	0.077632 (rank : 98)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	161	Target Neighborhood Hits	336	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
NC score	0.075778 (rank : 99)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	161	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

P85B_MOUSE
NC score	0.075574 (rank : 100)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	161	Target Neighborhood Hits	519	Shared Neighborhood Hits	53
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

DAPP1_MOUSE
NC score	0.071295 (rank : 101)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	161	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHA1_HUMAN
NC score	0.070511 (rank : 102)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	161	Target Neighborhood Hits	127	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

CIP4_HUMAN
NC score	0.069507 (rank : 103)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	161	Target Neighborhood Hits	374	Shared Neighborhood Hits	34
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

VINEX_MOUSE
NC score	0.068740 (rank : 104)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	161	Target Neighborhood Hits	286	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

NCK2_HUMAN
NC score	0.067936 (rank : 105)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	161	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

DAPP1_HUMAN
NC score	0.067395 (rank : 106)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	161	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GRB2_HUMAN
NC score	0.067179 (rank : 107)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	161	Target Neighborhood Hits	310	Shared Neighborhood Hits	22
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRAP_HUMAN
NC score	0.067132 (rank : 108)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	161	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRB2_MOUSE
NC score	0.067098 (rank : 109)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	161	Target Neighborhood Hits	312	Shared Neighborhood Hits	22
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

SH3K1_MOUSE
NC score	0.066604 (rank : 110)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	161	Target Neighborhood Hits	332	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

NCF4_MOUSE
NC score	0.066383 (rank : 111)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	161	Target Neighborhood Hits	177	Shared Neighborhood Hits	15
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

CD2AP_HUMAN
NC score	0.065861 (rank : 112)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	161	Target Neighborhood Hits	315	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y5K6, Q9UG97	Gene names	CD2AP
Domain Architecture
Description	CD2-associated protein (Cas ligand with multiple SH3 domains) (Adapter protein CMS).

PKHA1_MOUSE
NC score	0.065185 (rank : 113)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	161	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

SH3G2_MOUSE
NC score	0.064980 (rank : 114)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	161	Target Neighborhood Hits	319	Shared Neighborhood Hits	27
SwissProt Accessions	Q62420	Gene names	Sh3gl2, Sh3d2a
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (SH3p4).

GRAP_MOUSE
NC score	0.064817 (rank : 115)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	161	Target Neighborhood Hits	309	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

SRBS1_HUMAN
NC score	0.064456 (rank : 116)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	161	Target Neighborhood Hits	396	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

ITSN1_HUMAN
NC score	0.063961 (rank : 117)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	161	Target Neighborhood Hits	1757	Shared Neighborhood Hits	82
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

VINEX_HUMAN
NC score	0.063920 (rank : 118)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	161	Target Neighborhood Hits	270	Shared Neighborhood Hits	22
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

MYO10_HUMAN
NC score	0.063140 (rank : 119)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	161	Target Neighborhood Hits	920	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

STAC3_MOUSE
NC score	0.062713 (rank : 120)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	161	Target Neighborhood Hits	232	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

ITSN1_MOUSE
NC score	0.062459 (rank : 121)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	161	Target Neighborhood Hits	1669	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ABI2_HUMAN
NC score	0.062314 (rank : 122)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	161	Target Neighborhood Hits	350	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ABI2_MOUSE
NC score	0.061783 (rank : 123)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	161	Target Neighborhood Hits	266	Shared Neighborhood Hits	19
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

SH3K1_HUMAN
NC score	0.061758 (rank : 124)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	161	Target Neighborhood Hits	341	Shared Neighborhood Hits	25
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

SH3G2_HUMAN
NC score	0.061747 (rank : 125)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	161	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	Q99962, Q9NQK5	Gene names	SH3GL2, CNSA2, SH3D2A
Domain Architecture
Description	SH3-containing GRB2-like protein 2 (EC 2.3.1.-) (Endophilin-1) (Endophilin-A1) (SH3 domain protein 2A) (EEN-B1).

NUPL_HUMAN
NC score	0.061687 (rank : 126)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	161	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

SRBS1_MOUSE
NC score	0.061654 (rank : 127)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	161	Target Neighborhood Hits	409	Shared Neighborhood Hits	31
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

CT2NL_HUMAN
NC score	0.061290 (rank : 128)	θ value	0.00390308 (rank : 71)
Query Neighborhood Hits	161	Target Neighborhood Hits	1059	Shared Neighborhood Hits	61
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ITSN2_HUMAN
NC score	0.061234 (rank : 129)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	161	Target Neighborhood Hits	1173	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

NCF4_HUMAN
NC score	0.061185 (rank : 130)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	161	Target Neighborhood Hits	161	Shared Neighborhood Hits	13
SwissProt Accessions	Q15080, O60808, Q86U56, Q9BU98, Q9NP45	Gene names	NCF4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

ITSN2_MOUSE
NC score	0.061093 (rank : 131)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	161	Target Neighborhood Hits	1371	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

NUPL_MOUSE
NC score	0.061067 (rank : 132)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	161	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

STAC3_HUMAN
NC score	0.060781 (rank : 133)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	161	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

FA13A_HUMAN
NC score	0.060330 (rank : 134)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	161	Target Neighborhood Hits	102	Shared Neighborhood Hits	13
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

HCLS1_HUMAN
NC score	0.060291 (rank : 135)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	161	Target Neighborhood Hits	358	Shared Neighborhood Hits	22
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

FA13A_MOUSE
NC score	0.059808 (rank : 136)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	161	Target Neighborhood Hits	83	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

GRAP2_HUMAN
NC score	0.058814 (rank : 137)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	161	Target Neighborhood Hits	304	Shared Neighborhood Hits	21
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

HCLS1_MOUSE
NC score	0.058781 (rank : 138)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	161	Target Neighborhood Hits	329	Shared Neighborhood Hits	25
SwissProt Accessions	P49710	Gene names	Hcls1, Hs1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1).

PDZD8_HUMAN
NC score	0.058470 (rank : 139)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	161	Target Neighborhood Hits	185	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

MYO1F_MOUSE
NC score	0.058392 (rank : 140)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	161	Target Neighborhood Hits	262	Shared Neighborhood Hits	23
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

CD2AP_MOUSE
NC score	0.058249 (rank : 141)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	161	Target Neighborhood Hits	336	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

MYO1F_HUMAN
NC score	0.058124 (rank : 142)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	161	Target Neighborhood Hits	275	Shared Neighborhood Hits	25
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1E_HUMAN
NC score	0.057642 (rank : 143)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	161	Target Neighborhood Hits	293	Shared Neighborhood Hits	24
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

NCK1_HUMAN
NC score	0.057097 (rank : 144)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	161	Target Neighborhood Hits	312	Shared Neighborhood Hits	20
SwissProt Accessions	P16333	Gene names	NCK1, NCK
Domain Architecture
Description	Cytoplasmic protein NCK1 (NCK adaptor protein 1) (SH2/SH3 adaptor protein NCK-alpha).

NCF2_HUMAN
NC score	0.057076 (rank : 145)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	161	Target Neighborhood Hits	229	Shared Neighborhood Hits	19
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

P55G_HUMAN
NC score	0.057021 (rank : 146)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	161	Target Neighborhood Hits	451	Shared Neighborhood Hits	35
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

GRAP2_MOUSE
NC score	0.056209 (rank : 147)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	161	Target Neighborhood Hits	297	Shared Neighborhood Hits	22
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

HRBL_HUMAN
NC score	0.056160 (rank : 148)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	161	Target Neighborhood Hits	179	Shared Neighborhood Hits	14
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

MY18A_MOUSE
NC score	0.056040 (rank : 149)	θ value	0.163984 (rank : 77)
Query Neighborhood Hits	161	Target Neighborhood Hits	1989	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

VAV3_HUMAN
NC score	0.055775 (rank : 150)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	161	Target Neighborhood Hits	398	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

PKHA6_HUMAN
NC score	0.055556 (rank : 151)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	161	Target Neighborhood Hits	556	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

DGKH_HUMAN
NC score	0.055423 (rank : 152)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	161	Target Neighborhood Hits	255	Shared Neighborhood Hits	21
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DNMBP_HUMAN
NC score	0.055287 (rank : 153)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	161	Target Neighborhood Hits	413	Shared Neighborhood Hits	30
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

STAC_MOUSE
NC score	0.055234 (rank : 154)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	161	Target Neighborhood Hits	268	Shared Neighborhood Hits	18
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

PKHA6_MOUSE
NC score	0.055182 (rank : 155)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	161	Target Neighborhood Hits	591	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MY18A_HUMAN
NC score	0.055060 (rank : 156)	θ value	0.279714 (rank : 83)
Query Neighborhood Hits	161	Target Neighborhood Hits	1929	Shared Neighborhood Hits	79
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

VAV3_MOUSE
NC score	0.054786 (rank : 157)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	161	Target Neighborhood Hits	404	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ABI1_MOUSE
NC score	0.054675 (rank : 158)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	161	Target Neighborhood Hits	246	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

HRBL_MOUSE
NC score	0.054437 (rank : 159)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	161	Target Neighborhood Hits	269	Shared Neighborhood Hits	14
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

SH3G1_HUMAN
NC score	0.054099 (rank : 160)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	161	Target Neighborhood Hits	307	Shared Neighborhood Hits	29
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

MYO5A_MOUSE
NC score	0.054004 (rank : 161)	θ value	0.125558 (rank : 75)
Query Neighborhood Hits	161	Target Neighborhood Hits	1117	Shared Neighborhood Hits	56
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

CRKL_HUMAN
NC score	0.053702 (rank : 162)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	161	Target Neighborhood Hits	313	Shared Neighborhood Hits	22
SwissProt Accessions	P46109	Gene names	CRKL
Domain Architecture
Description	Crk-like protein.

P55G_MOUSE
NC score	0.053576 (rank : 163)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	161	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

MYO5A_HUMAN
NC score	0.052787 (rank : 164)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	161	Target Neighborhood Hits	1092	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

DNMBP_MOUSE
NC score	0.052165 (rank : 165)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	161	Target Neighborhood Hits	435	Shared Neighborhood Hits	33
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

ARHG7_MOUSE
NC score	0.052066 (rank : 166)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	161	Target Neighborhood Hits	396	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

PPIP1_HUMAN
NC score	0.052025 (rank : 167)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	161	Target Neighborhood Hits	389	Shared Neighborhood Hits	39
SwissProt Accessions	O43586, O43585, O95657	Gene names	PSTPIP1, CD2BP1
Domain Architecture	No domain graphic available
Description	Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1) (CD2-binding protein 1) (H-PIP).

SH3G1_MOUSE
NC score	0.051872 (rank : 168)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	161	Target Neighborhood Hits	291	Shared Neighborhood Hits	25
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

STAC_HUMAN
NC score	0.051242 (rank : 169)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	161	Target Neighborhood Hits	276	Shared Neighborhood Hits	18
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

PCTL_MOUSE
NC score	0.051085 (rank : 170)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	161	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PKHA2_MOUSE
NC score	0.050785 (rank : 171)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	161	Target Neighborhood Hits	116	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

MYO5C_HUMAN
NC score	0.050772 (rank : 172)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	161	Target Neighborhood Hits	1206	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

UN13B_HUMAN
NC score	0.050748 (rank : 173)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	161	Target Neighborhood Hits	217	Shared Neighborhood Hits	16
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

PCTL_HUMAN
NC score	0.050498 (rank : 174)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	161	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

UN13A_HUMAN
NC score	0.050401 (rank : 175)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	161	Target Neighborhood Hits	285	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

VAV2_HUMAN
NC score	0.050222 (rank : 176)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	161	Target Neighborhood Hits	453	Shared Neighborhood Hits	27
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
NC score	0.050011 (rank : 177)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	161	Target Neighborhood Hits	456	Shared Neighborhood Hits	25
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

RAD50_MOUSE
NC score	0.049703 (rank : 178)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	161	Target Neighborhood Hits	1366	Shared Neighborhood Hits	69
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RAD50_HUMAN
NC score	0.048819 (rank : 179)	θ value	0.163984 (rank : 78)
Query Neighborhood Hits	161	Target Neighborhood Hits	1317	Shared Neighborhood Hits	66
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

MYH11_MOUSE
NC score	0.048488 (rank : 180)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	161	Target Neighborhood Hits	1777	Shared Neighborhood Hits	74
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_HUMAN
NC score	0.047765 (rank : 181)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	161	Target Neighborhood Hits	1806	Shared Neighborhood Hits	74
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MIPO1_HUMAN
NC score	0.047332 (rank : 182)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	161	Target Neighborhood Hits	486	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

NEBU_HUMAN
NC score	0.047162 (rank : 183)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	161	Target Neighborhood Hits	420	Shared Neighborhood Hits	27
SwissProt Accessions	P20929, Q15346	Gene names	NEB
Domain Architecture
Description	Nebulin.

CR034_MOUSE
NC score	0.046098 (rank : 184)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	161	Target Neighborhood Hits	643	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

BICD1_MOUSE
NC score	0.044799 (rank : 185)	θ value	0.21417 (rank : 80)
Query Neighborhood Hits	161	Target Neighborhood Hits	837	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

SYCP1_HUMAN
NC score	0.044426 (rank : 186)	θ value	0.21417 (rank : 81)
Query Neighborhood Hits	161	Target Neighborhood Hits	1313	Shared Neighborhood Hits	66
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CENPF_HUMAN
NC score	0.044195 (rank : 187)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	161	Target Neighborhood Hits	1932	Shared Neighborhood Hits	83
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CCD46_HUMAN
NC score	0.044096 (rank : 188)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	161	Target Neighborhood Hits	1430	Shared Neighborhood Hits	73
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CE290_HUMAN
NC score	0.043320 (rank : 189)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	161	Target Neighborhood Hits	1553	Shared Neighborhood Hits	68
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

LUZP1_HUMAN
NC score	0.042389 (rank : 190)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	161	Target Neighborhood Hits	739	Shared Neighborhood Hits	49
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

TXLNB_HUMAN
NC score	0.042275 (rank : 191)	θ value	0.163984 (rank : 79)
Query Neighborhood Hits	161	Target Neighborhood Hits	912	Shared Neighborhood Hits	54
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

LRC45_HUMAN
NC score	0.041411 (rank : 192)	θ value	0.163984 (rank : 76)
Query Neighborhood Hits	161	Target Neighborhood Hits	933	Shared Neighborhood Hits	55
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CCD46_MOUSE
NC score	0.041367 (rank : 193)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	161	Target Neighborhood Hits	1405	Shared Neighborhood Hits	72
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CYTSA_MOUSE
NC score	0.041302 (rank : 194)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	161	Target Neighborhood Hits	1104	Shared Neighborhood Hits	63
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

BICD1_HUMAN
NC score	0.041202 (rank : 195)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	161	Target Neighborhood Hits	844	Shared Neighborhood Hits	59
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CYTSA_HUMAN
NC score	0.040745 (rank : 196)	θ value	0.279714 (rank : 82)
Query Neighborhood Hits	161	Target Neighborhood Hits	1138	Shared Neighborhood Hits	63
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

GCC2_MOUSE
NC score	0.039453 (rank : 197)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	161	Target Neighborhood Hits	1619	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CP250_HUMAN
NC score	0.038953 (rank : 198)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	161	Target Neighborhood Hits	1805	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CP135_HUMAN
NC score	0.037282 (rank : 199)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	161	Target Neighborhood Hits	1290	Shared Neighborhood Hits	64
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

HAP1_HUMAN
NC score	0.036821 (rank : 200)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	161	Target Neighborhood Hits	606	Shared Neighborhood Hits	49
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

SYNE1_HUMAN
NC score	0.035662 (rank : 201)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	161	Target Neighborhood Hits	1484	Shared Neighborhood Hits	72
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CCHCR_MOUSE
NC score	0.035196 (rank : 202)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	161	Target Neighborhood Hits	932	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

LUZP1_MOUSE
NC score	0.034979 (rank : 203)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	161	Target Neighborhood Hits	940	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

CCD39_HUMAN
NC score	0.034749 (rank : 204)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	161	Target Neighborhood Hits	868	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

K1219_HUMAN
NC score	0.032324 (rank : 205)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	161	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

EVPL_HUMAN
NC score	0.029742 (rank : 206)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	161	Target Neighborhood Hits	895	Shared Neighborhood Hits	53
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EP400_MOUSE
NC score	0.029558 (rank : 207)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	161	Target Neighborhood Hits	592	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

RUFY2_MOUSE
NC score	0.028883 (rank : 208)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	161	Target Neighborhood Hits	820	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

MACF1_MOUSE
NC score	0.028774 (rank : 209)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	161	Target Neighborhood Hits	1313	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

SM1L2_HUMAN
NC score	0.028656 (rank : 210)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	161	Target Neighborhood Hits	1019	Shared Neighborhood Hits	60
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

ANR11_HUMAN
NC score	0.028500 (rank : 211)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	161	Target Neighborhood Hits	1289	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CF060_HUMAN
NC score	0.028481 (rank : 212)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	161	Target Neighborhood Hits	1270	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

BPA1_MOUSE
NC score	0.027610 (rank : 213)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	161	Target Neighborhood Hits	1477	Shared Neighborhood Hits	59
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

K1219_MOUSE
NC score	0.026902 (rank : 214)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	161	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BQZ4, Q80TH5, Q8BQN1	Gene names	Kiaa1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

KIF4A_HUMAN
NC score	0.026275 (rank : 215)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	161	Target Neighborhood Hits	1159	Shared Neighborhood Hits	64
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

COG7_HUMAN
NC score	0.026239 (rank : 216)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	161	Target Neighborhood Hits	108	Shared Neighborhood Hits	14
SwissProt Accessions	P83436, Q6UWU7	Gene names	COG7
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 7.

MACF1_HUMAN
NC score	0.025319 (rank : 217)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	161	Target Neighborhood Hits	1341	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

CH013_HUMAN
NC score	0.024676 (rank : 218)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	161	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KS9, Q8N3M3, Q9NSR0	Gene names	C8orf13
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C8orf13.

BRD4_HUMAN
NC score	0.023559 (rank : 219)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	161	Target Neighborhood Hits	851	Shared Neighborhood Hits	44
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

ANGP2_HUMAN
NC score	0.023230 (rank : 220)	θ value	0.47712 (rank : 89)
Query Neighborhood Hits	161	Target Neighborhood Hits	400	Shared Neighborhood Hits	38
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

RADI_MOUSE
NC score	0.023103 (rank : 221)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	161	Target Neighborhood Hits	773	Shared Neighborhood Hits	51
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

OGFR_HUMAN
NC score	0.022567 (rank : 222)	θ value	0.47712 (rank : 90)
Query Neighborhood Hits	161	Target Neighborhood Hits	1582	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NEST_HUMAN
NC score	0.021726 (rank : 223)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	161	Target Neighborhood Hits	1305	Shared Neighborhood Hits	59
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

BRD4_MOUSE
NC score	0.020973 (rank : 224)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	161	Target Neighborhood Hits	845	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

RL1D1_HUMAN
NC score	0.020161 (rank : 225)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	161	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

ATX2_HUMAN
NC score	0.019930 (rank : 226)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	161	Target Neighborhood Hits	375	Shared Neighborhood Hits	11
SwissProt Accessions	Q99700, Q6ZQZ7, Q99493	Gene names	ATXN2, ATX2, SCA2, TNRC13
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein) (Trinucleotide repeat-containing gene 13 protein).

CTRO_MOUSE
NC score	0.019911 (rank : 227)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	161	Target Neighborhood Hits	2344	Shared Neighborhood Hits	75
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ATX2_MOUSE
NC score	0.019249 (rank : 228)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	161	Target Neighborhood Hits	445	Shared Neighborhood Hits	14
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

GP153_HUMAN
NC score	0.017368 (rank : 229)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	161	Target Neighborhood Hits	332	Shared Neighborhood Hits	8
SwissProt Accessions	Q6NV75, Q5TGR5, Q6AHW8, Q86SP8	Gene names	GPR153, PGR1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

CTRO_HUMAN
NC score	0.016178 (rank : 230)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	161	Target Neighborhood Hits	2092	Shared Neighborhood Hits	67
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CRSP7_HUMAN
NC score	0.016123 (rank : 231)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	161	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

JADE2_MOUSE
NC score	0.015639 (rank : 232)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	161	Target Neighborhood Hits	560	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

FER_HUMAN
NC score	0.015324 (rank : 233)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	161	Target Neighborhood Hits	1278	Shared Neighborhood Hits	52
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

EXOC3_MOUSE
NC score	0.014301 (rank : 234)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	161	Target Neighborhood Hits	85	Shared Neighborhood Hits	7
SwissProt Accessions	Q6KAR6	Gene names	Exoc3, Sec6l1
Domain Architecture	No domain graphic available
Description	Exocyst complex component 3 (Exocyst complex component Sec6).

CHCH6_MOUSE
NC score	0.013899 (rank : 235)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	161	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	Q91VN4	Gene names	Chchd6
Domain Architecture	No domain graphic available
Description	Coiled-coil-helix-coiled-coil-helix domain-containing protein 6.

GEMI5_MOUSE
NC score	0.013843 (rank : 236)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	161	Target Neighborhood Hits	424	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

CRSP2_HUMAN
NC score	0.013608 (rank : 237)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	161	Target Neighborhood Hits	380	Shared Neighborhood Hits	10
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

NUCB2_HUMAN
NC score	0.013406 (rank : 238)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	161	Target Neighborhood Hits	321	Shared Neighborhood Hits	30
SwissProt Accessions	P80303, Q8NFT5	Gene names	NUCB2, NEFA
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4).

BXDC2_MOUSE
NC score	0.012327 (rank : 239)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	161	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCA5, Q91YS6	Gene names	Bxdc2, Brix
Domain Architecture
Description	Brix domain-containing protein 2 (Ribosome biogenesis protein Brix).

SYN2_HUMAN
NC score	0.011138 (rank : 240)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	161	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

MLL3_HUMAN
NC score	0.010735 (rank : 241)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	161	Target Neighborhood Hits	1644	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SMRC1_MOUSE
NC score	0.010389 (rank : 242)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	161	Target Neighborhood Hits	459	Shared Neighborhood Hits	22
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

EPN1_HUMAN
NC score	0.010370 (rank : 243)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	161	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

BAZ1B_HUMAN
NC score	0.009821 (rank : 244)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	161	Target Neighborhood Hits	701	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

SEP11_HUMAN
NC score	0.009804 (rank : 245)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	161	Target Neighborhood Hits	296	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NVA2, Q7L4N1	Gene names	SEPT11
Domain Architecture	No domain graphic available
Description	Septin-11.

DIAP3_MOUSE
NC score	0.009661 (rank : 246)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	161	Target Neighborhood Hits	221	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z207	Gene names	Diaph3, Diap3
Domain Architecture
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2).

PPRB_HUMAN
NC score	0.009409 (rank : 247)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	161	Target Neighborhood Hits	311	Shared Neighborhood Hits	12
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PTN23_MOUSE
NC score	0.009274 (rank : 248)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	161	Target Neighborhood Hits	726	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

BAP1_MOUSE
NC score	0.008246 (rank : 249)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	161	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

HS74L_MOUSE
NC score	0.004231 (rank : 250)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	161	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

STK10_HUMAN
NC score	0.003850 (rank : 251)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	161	Target Neighborhood Hits	1921	Shared Neighborhood Hits	62
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SEM4C_HUMAN
NC score	0.002899 (rank : 252)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	161	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0C4, Q7Z5X0	Gene names	SEMA4C, KIAA1739
Domain Architecture
Description	Semaphorin-4C precursor.

MAST4_HUMAN
NC score	0.002172 (rank : 253)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	161	Target Neighborhood Hits	1804	Shared Neighborhood Hits	38
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

LHX1_HUMAN
NC score	0.001836 (rank : 254)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	161	Target Neighborhood Hits	453	Shared Neighborhood Hits	4
SwissProt Accessions	P48742, Q3MIW0	Gene names	LHX1, LIM1
Domain Architecture
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

LHX1_MOUSE
NC score	0.001192 (rank : 255)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	161	Target Neighborhood Hits	453	Shared Neighborhood Hits	4
SwissProt Accessions	P63006, P36199	Gene names	Lhx1, Lim-1, Lim1
Domain Architecture	No domain graphic available
Description	LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1).

UTP15_MOUSE
NC score	-0.000688 (rank : 256)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	161	Target Neighborhood Hits	309	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C7V3, Q3TRG8, Q8K231	Gene names	Utp15
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW).