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Network neighborhood for query Sequence : STA13_HUMAN

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STA13_HUMAN
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RHG07_HUMAN
θ value	0 (rank : 1)	NC score	0.982960 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	108	Shared Neighborhood Hits	66
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_MOUSE
θ value	0 (rank : 2)	NC score	0.982992 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

STA13_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
θ value	0 (rank : 4)	NC score	0.997673 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

STAR8_HUMAN
θ value	0 (rank : 5)	NC score	0.960771 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	216	Shared Neighborhood Hits	64
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_MOUSE
θ value	0 (rank : 6)	NC score	0.971763 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	101	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG18_MOUSE
θ value	1.92812e-18 (rank : 7)	NC score	0.725259 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG04_HUMAN
θ value	3.07829e-16 (rank : 8)	NC score	0.608559 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG18_HUMAN
θ value	8.95645e-16 (rank : 9)	NC score	0.715308 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

3BP1_HUMAN
θ value	1.16975e-15 (rank : 10)	NC score	0.660177 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	376	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GRLF1_HUMAN
θ value	1.16975e-15 (rank : 11)	NC score	0.641241 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	167	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RBP1_MOUSE
θ value	3.40345e-15 (rank : 12)	NC score	0.616876 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	493	Shared Neighborhood Hits	61
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

MYO9B_MOUSE
θ value	1.29331e-14 (rank : 13)	NC score	0.345500 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	311	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RBP1_HUMAN
θ value	2.20605e-14 (rank : 14)	NC score	0.594601 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	521	Shared Neighborhood Hits	61
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

SRGP2_HUMAN
θ value	2.88119e-14 (rank : 15)	NC score	0.581918 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

MYO9B_HUMAN
θ value	3.76295e-14 (rank : 16)	NC score	0.340233 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	641	Shared Neighborhood Hits	61
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RHG06_MOUSE
θ value	4.91457e-14 (rank : 17)	NC score	0.691220 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SRGP2_MOUSE
θ value	3.18553e-13 (rank : 18)	NC score	0.572631 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	324	Shared Neighborhood Hits	60
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

RHG06_HUMAN
θ value	5.43371e-13 (rank : 19)	NC score	0.688082 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

SRGP1_HUMAN
θ value	5.43371e-13 (rank : 20)	NC score	0.561773 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	390	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

3BP1_MOUSE
θ value	7.09661e-13 (rank : 21)	NC score	0.673647 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	238	Shared Neighborhood Hits	59
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

FNBP2_HUMAN
θ value	7.09661e-13 (rank : 22)	NC score	0.565190 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	432	Shared Neighborhood Hits	59
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

RHG12_MOUSE
θ value	2.69671e-12 (rank : 23)	NC score	0.626906 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	204	Shared Neighborhood Hits	59
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_HUMAN
θ value	3.52202e-12 (rank : 24)	NC score	0.631003 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	190	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

ABR_HUMAN
θ value	1.02475e-11 (rank : 25)	NC score	0.576074 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	59
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG01_HUMAN
θ value	1.02475e-11 (rank : 26)	NC score	0.630814 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

TCGAP_HUMAN
θ value	1.133e-10 (rank : 27)	NC score	0.524386 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	872	Shared Neighborhood Hits	59
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	1.133e-10 (rank : 28)	NC score	0.591115 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	409	Shared Neighborhood Hits	59
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

BCR_HUMAN
θ value	1.9326e-10 (rank : 29)	NC score	0.563220 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	204	Shared Neighborhood Hits	59
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

CEND2_HUMAN
θ value	2.52405e-10 (rank : 30)	NC score	0.495949 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	57
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_MOUSE
θ value	2.52405e-10 (rank : 31)	NC score	0.486887 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CHIN_HUMAN
θ value	9.59137e-10 (rank : 32)	NC score	0.552387 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	227	Shared Neighborhood Hits	58
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CEND3_HUMAN
θ value	1.63604e-09 (rank : 33)	NC score	0.475740 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	275	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

RHG05_MOUSE
θ value	1.63604e-09 (rank : 34)	NC score	0.575009 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CHIO_MOUSE
θ value	3.64472e-09 (rank : 35)	NC score	0.576082 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

GMIP_MOUSE
θ value	4.76016e-09 (rank : 36)	NC score	0.618678 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	202	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CHIN_MOUSE
θ value	6.21693e-09 (rank : 37)	NC score	0.547177 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	229	Shared Neighborhood Hits	59
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	8.11959e-09 (rank : 38)	NC score	0.546515 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	220	Shared Neighborhood Hits	58
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG08_MOUSE
θ value	8.11959e-09 (rank : 39)	NC score	0.589957 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

OPHN1_MOUSE
θ value	1.06045e-08 (rank : 40)	NC score	0.575899 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	174	Shared Neighborhood Hits	60
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG05_HUMAN
θ value	1.06045e-08 (rank : 41)	NC score	0.563566 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	158	Shared Neighborhood Hits	60
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

GMIP_HUMAN
θ value	2.36244e-08 (rank : 42)	NC score	0.612934 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	225	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG26_HUMAN
θ value	2.36244e-08 (rank : 43)	NC score	0.551703 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	281	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

OPHN1_HUMAN
θ value	3.08544e-08 (rank : 44)	NC score	0.571896 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	161	Shared Neighborhood Hits	59
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RHG08_HUMAN
θ value	4.0297e-08 (rank : 45)	NC score	0.580045 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	88	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG09_HUMAN
θ value	7.59969e-07 (rank : 46)	NC score	0.620046 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	186	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG25_MOUSE
θ value	2.88788e-06 (rank : 47)	NC score	0.535488 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	492	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RGAP1_HUMAN
θ value	3.77169e-06 (rank : 48)	NC score	0.591726 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	189	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

PCTL_MOUSE
θ value	4.92598e-06 (rank : 49)	NC score	0.326276 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
θ value	6.43352e-06 (rank : 50)	NC score	0.323388 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

CE005_MOUSE
θ value	8.40245e-06 (rank : 51)	NC score	0.505586 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	238	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CE005_HUMAN
θ value	1.43324e-05 (rank : 52)	NC score	0.506080 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	213	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

RHG25_HUMAN
θ value	1.43324e-05 (rank : 53)	NC score	0.519816 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	550	Shared Neighborhood Hits	58
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TAGAP_MOUSE
θ value	0.000158464 (rank : 54)	NC score	0.563659 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	83	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_HUMAN
θ value	0.000270298 (rank : 55)	NC score	0.571970 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RGAP1_MOUSE
θ value	0.00298849 (rank : 56)	NC score	0.563339 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	185	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

K1688_MOUSE
θ value	0.00390308 (rank : 57)	NC score	0.408370 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	188	Shared Neighborhood Hits	56
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
θ value	0.00509761 (rank : 58)	NC score	0.396724 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	217	Shared Neighborhood Hits	56
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

STAR7_HUMAN
θ value	0.00665767 (rank : 59)	NC score	0.177036 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQZ5, Q6GU43, Q969M6	Gene names	STARD7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7) (Protein GTT1).

CEND1_MOUSE
θ value	0.0193708 (rank : 60)	NC score	0.356028 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	260	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND1_HUMAN
θ value	0.0431538 (rank : 61)	NC score	0.339933 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	284	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

STAR7_MOUSE
θ value	0.0736092 (rank : 62)	NC score	0.158636 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R1R3	Gene names	Stard7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7).

STAR_HUMAN
θ value	0.0961366 (rank : 63)	NC score	0.073298 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	P49675, Q16396	Gene names	STAR
Domain Architecture
Description	Steroidogenic acute regulatory protein, mitochondrial precursor (StAR) (StARD1).

CUL7_HUMAN
θ value	0.279714 (rank : 64)	NC score	0.022759 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

STAR_MOUSE
θ value	0.47712 (rank : 65)	NC score	0.065440 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	P51557, Q543A5, Q924Y5, Q9D2G1	Gene names	Star
Domain Architecture
Description	Steroidogenic acute regulatory protein, mitochondrial precursor (StAR) (StARD1) (Luteinizing hormone-induced protein).

ZN462_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.001281 (rank : 91)
Query Neighborhood Hits	89	Target Neighborhood Hits	740	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JM2, Q8N408	Gene names	ZNF462, KIAA1803
Domain Architecture	No domain graphic available
Description	Zinc finger protein 462.

ACO11_HUMAN
θ value	0.62314 (rank : 67)	NC score	0.048463 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXI4, O75187, Q96DI1, Q9H883	Gene names	ACOT11, BFIT, KIAA0707, THEA
Domain Architecture
Description	Acyl-coenzyme A thioesterase 11 (EC 3.1.2.-) (Acyl-CoA thioesterase 11) (Acyl-CoA thioester hydrolase 11) (Brown fat-inducible thioesterase) (BFIT) (Adipose-associated thioesterase).

STAT2_MOUSE
θ value	0.62314 (rank : 68)	NC score	0.018421 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

ACO12_MOUSE
θ value	1.06291 (rank : 69)	NC score	0.067275 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBK0, Q544M5, Q8R108	Gene names	Acot12, Cach, Cach1
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (mCACH-1).

DTBP1_MOUSE
θ value	1.06291 (rank : 70)	NC score	0.018677 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

UN45B_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.011966 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWX7, Q495Q8, Q495Q9	Gene names	UNC45B, CMYA4, UNC45
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

OSTP_MOUSE
θ value	1.81305 (rank : 72)	NC score	0.030391 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

GP149_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.015618 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

FRS3_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.009519 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	168	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

MMRN1_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.006164 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	636	Shared Neighborhood Hits	9
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MYH2_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.016412 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	1491	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

ACO12_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.045458 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WYK0	Gene names	ACOT12, CACH, CACH1, STARD12
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (hCACH-1) (START domain-containing protein 12) (StARD12).

B3GN1_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.010088 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z222, Q91V18	Gene names	B3gnt1, Beta3gnt
Domain Architecture	No domain graphic available
Description	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 (EC 2.4.1.-) (Beta3Gn-T1) (BGnT-1) (Beta-1,3-galactosyltransferase 7) (Beta-1,3-GalTase 7) (Beta3Gal-T7) (b3Gal-T7) (UDP-galactose:beta-N- acetylglucosamine beta-1,3-galactosyltransferase 7) (UDP-Gal:beta- GlcNAc beta-1,3-galactosyltransferase 7) (Beta-3-Gx-T7).

CN103_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.010541 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XK6, Q8R1H5, Q9CWK6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf103 homolog.

K2027_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.016367 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

LRP1_HUMAN
θ value	5.27518 (rank : 81)	NC score	-0.000429 (rank : 92)
Query Neighborhood Hits	89	Target Neighborhood Hits	617	Shared Neighborhood Hits	3
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

PAR14_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.007414 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

SFRIP_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.017437 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	530	Shared Neighborhood Hits	5
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

YYAP1_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.010666 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H869, Q5VYZ4, Q5VYZ7, Q7L4C3, Q7L5E2, Q8IXA6, Q8TEW5, Q8TF04, Q96HB6, Q9BQ64, Q9NV84	Gene names	YY1AP1, HCCA2, YY1AP
Domain Architecture	No domain graphic available
Description	YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2).

AMPE_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.003759 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q07075	Gene names	ENPEP
Domain Architecture
Description	Glutamyl aminopeptidase (EC 3.4.11.7) (EAP) (Aminopeptidase A) (APA) (Differentiation antigen gp160) (CD249 antigen).

MLTK_HUMAN
θ value	6.88961 (rank : 86)	NC score	-0.004934 (rank : 93)
Query Neighborhood Hits	89	Target Neighborhood Hits	911	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

P85A_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.229887 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	479	Shared Neighborhood Hits	57
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

HIRA_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.006708 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	P54198, Q8IXN2	Gene names	HIRA, DGCR1, HIR, TUPLE1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

HIRA_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.008120 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q61666, O08845, Q62365	Gene names	Hira, Tuple1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

CCD48_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.050884 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HA90	Gene names	CCDC48
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 48.

I5P2_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.219801 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	86	Shared Neighborhood Hits	49
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.189633 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

P85A_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.226580 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	435	Shared Neighborhood Hits	56
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

Hits sorted by NC score

STA13_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
NC score	0.997673 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	72
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

RHG07_MOUSE
NC score	0.982992 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	103	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_HUMAN
NC score	0.982960 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	108	Shared Neighborhood Hits	66
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

STAR8_MOUSE
NC score	0.971763 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	101	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_HUMAN
NC score	0.960771 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	216	Shared Neighborhood Hits	64
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RHG18_MOUSE
NC score	0.725259 (rank : 7)	θ value	1.92812e-18 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG18_HUMAN
NC score	0.715308 (rank : 8)	θ value	8.95645e-16 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG06_MOUSE
NC score	0.691220 (rank : 9)	θ value	4.91457e-14 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	105	Shared Neighborhood Hits	59
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_HUMAN
NC score	0.688082 (rank : 10)	θ value	5.43371e-13 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_MOUSE
NC score	0.673647 (rank : 11)	θ value	7.09661e-13 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	238	Shared Neighborhood Hits	59
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_HUMAN
NC score	0.660177 (rank : 12)	θ value	1.16975e-15 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	376	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

GRLF1_HUMAN
NC score	0.641241 (rank : 13)	θ value	1.16975e-15 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	167	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG12_HUMAN
NC score	0.631003 (rank : 14)	θ value	3.52202e-12 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	190	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG01_HUMAN
NC score	0.630814 (rank : 15)	θ value	1.02475e-11 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG12_MOUSE
NC score	0.626906 (rank : 16)	θ value	2.69671e-12 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	204	Shared Neighborhood Hits	59
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG09_HUMAN
NC score	0.620046 (rank : 17)	θ value	7.59969e-07 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	186	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

GMIP_MOUSE
NC score	0.618678 (rank : 18)	θ value	4.76016e-09 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	202	Shared Neighborhood Hits	59
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RBP1_MOUSE
NC score	0.616876 (rank : 19)	θ value	3.40345e-15 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	493	Shared Neighborhood Hits	61
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

GMIP_HUMAN
NC score	0.612934 (rank : 20)	θ value	2.36244e-08 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	225	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG04_HUMAN
NC score	0.608559 (rank : 21)	θ value	3.07829e-16 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RBP1_HUMAN
NC score	0.594601 (rank : 22)	θ value	2.20605e-14 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	521	Shared Neighborhood Hits	61
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RGAP1_HUMAN
NC score	0.591726 (rank : 23)	θ value	3.77169e-06 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	189	Shared Neighborhood Hits	60
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

TCGAP_MOUSE
NC score	0.591115 (rank : 24)	θ value	1.133e-10 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	409	Shared Neighborhood Hits	59
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG08_MOUSE
NC score	0.589957 (rank : 25)	θ value	8.11959e-09 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	73	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

SRGP2_HUMAN
NC score	0.581918 (rank : 26)	θ value	2.88119e-14 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG08_HUMAN
NC score	0.580045 (rank : 27)	θ value	4.0297e-08 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	88	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

CHIO_MOUSE
NC score	0.576082 (rank : 28)	θ value	3.64472e-09 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

ABR_HUMAN
NC score	0.576074 (rank : 29)	θ value	1.02475e-11 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	59
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

OPHN1_MOUSE
NC score	0.575899 (rank : 30)	θ value	1.06045e-08 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	174	Shared Neighborhood Hits	60
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RHG05_MOUSE
NC score	0.575009 (rank : 31)	θ value	1.63604e-09 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SRGP2_MOUSE
NC score	0.572631 (rank : 32)	θ value	3.18553e-13 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	324	Shared Neighborhood Hits	60
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

TAGAP_HUMAN
NC score	0.571970 (rank : 33)	θ value	0.000270298 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

OPHN1_HUMAN
NC score	0.571896 (rank : 34)	θ value	3.08544e-08 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	161	Shared Neighborhood Hits	59
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

FNBP2_HUMAN
NC score	0.565190 (rank : 35)	θ value	7.09661e-13 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	432	Shared Neighborhood Hits	59
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

TAGAP_MOUSE
NC score	0.563659 (rank : 36)	θ value	0.000158464 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	83	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

RHG05_HUMAN
NC score	0.563566 (rank : 37)	θ value	1.06045e-08 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	158	Shared Neighborhood Hits	60
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RGAP1_MOUSE
NC score	0.563339 (rank : 38)	θ value	0.00298849 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	185	Shared Neighborhood Hits	59
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

BCR_HUMAN
NC score	0.563220 (rank : 39)	θ value	1.9326e-10 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	204	Shared Neighborhood Hits	59
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

SRGP1_HUMAN
NC score	0.561773 (rank : 40)	θ value	5.43371e-13 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	390	Shared Neighborhood Hits	60
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

CHIN_HUMAN
NC score	0.552387 (rank : 41)	θ value	9.59137e-10 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	227	Shared Neighborhood Hits	58
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

RHG26_HUMAN
NC score	0.551703 (rank : 42)	θ value	2.36244e-08 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	281	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

CHIN_MOUSE
NC score	0.547177 (rank : 43)	θ value	6.21693e-09 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	229	Shared Neighborhood Hits	59
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
NC score	0.546515 (rank : 44)	θ value	8.11959e-09 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	220	Shared Neighborhood Hits	58
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG25_MOUSE
NC score	0.535488 (rank : 45)	θ value	2.88788e-06 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	492	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TCGAP_HUMAN
NC score	0.524386 (rank : 46)	θ value	1.133e-10 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	872	Shared Neighborhood Hits	59
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG25_HUMAN
NC score	0.519816 (rank : 47)	θ value	1.43324e-05 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	550	Shared Neighborhood Hits	58
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

CE005_HUMAN
NC score	0.506080 (rank : 48)	θ value	1.43324e-05 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	213	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.505586 (rank : 49)	θ value	8.40245e-06 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	238	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CEND2_HUMAN
NC score	0.495949 (rank : 50)	θ value	2.52405e-10 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	166	Shared Neighborhood Hits	57
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CEND3_MOUSE
NC score	0.486887 (rank : 51)	θ value	2.52405e-10 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	228	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

CEND3_HUMAN
NC score	0.475740 (rank : 52)	θ value	1.63604e-09 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	275	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

K1688_MOUSE
NC score	0.408370 (rank : 53)	θ value	0.00390308 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	188	Shared Neighborhood Hits	56
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

K1688_HUMAN
NC score	0.396724 (rank : 54)	θ value	0.00509761 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	217	Shared Neighborhood Hits	56
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CEND1_MOUSE
NC score	0.356028 (rank : 55)	θ value	0.0193708 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	260	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

MYO9B_MOUSE
NC score	0.345500 (rank : 56)	θ value	1.29331e-14 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	311	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.340233 (rank : 57)	θ value	3.76295e-14 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	641	Shared Neighborhood Hits	61
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CEND1_HUMAN
NC score	0.339933 (rank : 58)	θ value	0.0431538 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	284	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

PCTL_MOUSE
NC score	0.326276 (rank : 59)	θ value	4.92598e-06 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JMD3	Gene names	Stard10, Pctpl, Sdccag28, Sdccagg28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28 homolog).

PCTL_HUMAN
NC score	0.323388 (rank : 60)	θ value	6.43352e-06 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y365, O60532	Gene names	STARD10, SDCCAG28
Domain Architecture
Description	PCTP-like protein (PCTP-L) (StAR-related lipid transfer protein 10) (StARD10) (START domain-containing protein 10) (Serologically defined colon cancer antigen 28) (Antigen NY-CO-28).

P85A_HUMAN
NC score	0.229887 (rank : 61)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	479	Shared Neighborhood Hits	57
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.226580 (rank : 62)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	89	Target Neighborhood Hits	435	Shared Neighborhood Hits	56
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

I5P2_HUMAN
NC score	0.219801 (rank : 63)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	89	Target Neighborhood Hits	86	Shared Neighborhood Hits	49
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

OCRL_HUMAN
NC score	0.189633 (rank : 64)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	89	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

STAR7_HUMAN
NC score	0.177036 (rank : 65)	θ value	0.00665767 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NQZ5, Q6GU43, Q969M6	Gene names	STARD7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7) (Protein GTT1).

STAR7_MOUSE
NC score	0.158636 (rank : 66)	θ value	0.0736092 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R1R3	Gene names	Stard7
Domain Architecture
Description	StAR-related lipid transfer protein 7 (StARD7) (START domain- containing protein 7).

STAR_HUMAN
NC score	0.073298 (rank : 67)	θ value	0.0961366 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	16	Shared Neighborhood Hits	7
SwissProt Accessions	P49675, Q16396	Gene names	STAR
Domain Architecture
Description	Steroidogenic acute regulatory protein, mitochondrial precursor (StAR) (StARD1).

ACO12_MOUSE
NC score	0.067275 (rank : 68)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DBK0, Q544M5, Q8R108	Gene names	Acot12, Cach, Cach1
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (mCACH-1).

STAR_MOUSE
NC score	0.065440 (rank : 69)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	P51557, Q543A5, Q924Y5, Q9D2G1	Gene names	Star
Domain Architecture
Description	Steroidogenic acute regulatory protein, mitochondrial precursor (StAR) (StARD1) (Luteinizing hormone-induced protein).

CCD48_HUMAN
NC score	0.050884 (rank : 70)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HA90	Gene names	CCDC48
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 48.

ACO11_HUMAN
NC score	0.048463 (rank : 71)	θ value	0.62314 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXI4, O75187, Q96DI1, Q9H883	Gene names	ACOT11, BFIT, KIAA0707, THEA
Domain Architecture
Description	Acyl-coenzyme A thioesterase 11 (EC 3.1.2.-) (Acyl-CoA thioesterase 11) (Acyl-CoA thioester hydrolase 11) (Brown fat-inducible thioesterase) (BFIT) (Adipose-associated thioesterase).

ACO12_HUMAN
NC score	0.045458 (rank : 72)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WYK0	Gene names	ACOT12, CACH, CACH1, STARD12
Domain Architecture
Description	Acyl-coenzyme A thioesterase 12 (EC 3.1.2.1) (Acyl-CoA thioesterase 12) (Acyl-CoA thioester hydrolase 12) (Cytoplasmic acetyl-CoA hydrolase 1) (CACH-1) (hCACH-1) (START domain-containing protein 12) (StARD12).

OSTP_MOUSE
NC score	0.030391 (rank : 73)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

CUL7_HUMAN
NC score	0.022759 (rank : 74)	θ value	0.279714 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

DTBP1_MOUSE
NC score	0.018677 (rank : 75)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	209	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WZ8, Q80ZN4	Gene names	Dtnbp1
Domain Architecture
Description	Dystrobrevin-binding protein 1 (Dysbindin) (Hermansky-Pudlak syndrome 7 protein homolog).

STAT2_MOUSE
NC score	0.018421 (rank : 76)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

SFRIP_HUMAN
NC score	0.017437 (rank : 77)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	530	Shared Neighborhood Hits	5
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

MYH2_HUMAN
NC score	0.016412 (rank : 78)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	1491	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

K2027_MOUSE
NC score	0.016367 (rank : 79)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

GP149_HUMAN
NC score	0.015618 (rank : 80)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

UN45B_HUMAN
NC score	0.011966 (rank : 81)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWX7, Q495Q8, Q495Q9	Gene names	UNC45B, CMYA4, UNC45
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

YYAP1_HUMAN
NC score	0.010666 (rank : 82)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H869, Q5VYZ4, Q5VYZ7, Q7L4C3, Q7L5E2, Q8IXA6, Q8TEW5, Q8TF04, Q96HB6, Q9BQ64, Q9NV84	Gene names	YY1AP1, HCCA2, YY1AP
Domain Architecture	No domain graphic available
Description	YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2).

CN103_MOUSE
NC score	0.010541 (rank : 83)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XK6, Q8R1H5, Q9CWK6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf103 homolog.

B3GN1_MOUSE
NC score	0.010088 (rank : 84)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z222, Q91V18	Gene names	B3gnt1, Beta3gnt
Domain Architecture	No domain graphic available
Description	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 (EC 2.4.1.-) (Beta3Gn-T1) (BGnT-1) (Beta-1,3-galactosyltransferase 7) (Beta-1,3-GalTase 7) (Beta3Gal-T7) (b3Gal-T7) (UDP-galactose:beta-N- acetylglucosamine beta-1,3-galactosyltransferase 7) (UDP-Gal:beta- GlcNAc beta-1,3-galactosyltransferase 7) (Beta-3-Gx-T7).

FRS3_MOUSE
NC score	0.009519 (rank : 85)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	168	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

HIRA_MOUSE
NC score	0.008120 (rank : 86)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q61666, O08845, Q62365	Gene names	Hira, Tuple1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

PAR14_MOUSE
NC score	0.007414 (rank : 87)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

HIRA_HUMAN
NC score	0.006708 (rank : 88)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	P54198, Q8IXN2	Gene names	HIRA, DGCR1, HIR, TUPLE1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

MMRN1_HUMAN
NC score	0.006164 (rank : 89)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	636	Shared Neighborhood Hits	9
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

AMPE_HUMAN
NC score	0.003759 (rank : 90)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q07075	Gene names	ENPEP
Domain Architecture
Description	Glutamyl aminopeptidase (EC 3.4.11.7) (EAP) (Aminopeptidase A) (APA) (Differentiation antigen gp160) (CD249 antigen).

ZN462_HUMAN
NC score	0.001281 (rank : 91)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	740	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JM2, Q8N408	Gene names	ZNF462, KIAA1803
Domain Architecture	No domain graphic available
Description	Zinc finger protein 462.

LRP1_HUMAN
NC score	-0.000429 (rank : 92)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	617	Shared Neighborhood Hits	3
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MLTK_HUMAN
NC score	-0.004934 (rank : 93)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	911	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).