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Network neighborhood for query Sequence : GP149_HUMAN

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GP149_HUMAN
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GP149_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

GP149_MOUSE
θ value	0 (rank : 2)	NC score	0.963939 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	61	Shared Neighborhood Hits	18
SwissProt Accessions	Q3UVY1, Q3TMB1, Q80T52, Q8BXA3, Q8BZC0	Gene names	Gpr149, Pgr10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

OPN4_HUMAN
θ value	0.000786445 (rank : 3)	NC score	0.087204 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	923	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHM6, Q2PP22, Q8NGQ9	Gene names	OPN4, MOP
Domain Architecture
Description	Melanopsin (Opsin-4).

RGR_MOUSE
θ value	0.00102713 (rank : 4)	NC score	0.179610 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	209	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z2B3	Gene names	Rgr
Domain Architecture
Description	RPE-retinal G protein-coupled receptor.

OPN4_MOUSE
θ value	0.00134147 (rank : 5)	NC score	0.087963 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	916	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXZ9	Gene names	Opn4, Mop, Mopn
Domain Architecture
Description	Melanopsin (Opsin-4).

RGR_HUMAN
θ value	0.0148317 (rank : 6)	NC score	0.154312 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	P47804, Q96FC5	Gene names	RGR
Domain Architecture
Description	RPE-retinal G protein-coupled receptor.

OR2LD_HUMAN
θ value	0.0193708 (rank : 7)	NC score	0.014041 (rank : 77)
Query Neighborhood Hits	68	Target Neighborhood Hits	760	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N349, Q5VUR5	Gene names	OR2L13, OR2L14
Domain Architecture
Description	Olfactory receptor 2L13.

MCHR2_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.060907 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	562	Shared Neighborhood Hits	30
SwissProt Accessions	Q969V1, Q6Q377, Q9BXA8	Gene names	MCHR2, GPR145, SLT
Domain Architecture
Description	Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCHR-2) (MCH-R2) (MCH2R) (MCH-2R) (MCH2) (G-protein coupled receptor 145) (GPRv17).

5HT1A_MOUSE
θ value	0.0961366 (rank : 9)	NC score	0.063869 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	891	Shared Neighborhood Hits	39
SwissProt Accessions	Q64264, Q60956, Q61617	Gene names	Htr1a, Gpcr18
Domain Architecture
Description	5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5- HT1A).

GPBAR_MOUSE
θ value	0.163984 (rank : 10)	NC score	0.125864 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	155	Shared Neighborhood Hits	24
SwissProt Accessions	Q80SS6	Gene names	Gpbar1, Tgr5
Domain Architecture	No domain graphic available
Description	G-protein coupled bile acid receptor 1 (Membrane-type receptor for bile acids) (M-BAR).

5HT1A_HUMAN
θ value	0.279714 (rank : 11)	NC score	0.063333 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	887	Shared Neighborhood Hits	39
SwissProt Accessions	P08908, Q6LAE7	Gene names	HTR1A
Domain Architecture
Description	5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5- HT1A) (G-21).

EDG7_MOUSE
θ value	0.279714 (rank : 12)	NC score	0.055438 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	602	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EQ31	Gene names	Edg7, Lpa3
Domain Architecture
Description	Lysophosphatidic acid receptor Edg-7 (LPA receptor 3) (LPA-3).

GP162_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.113544 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	244	Shared Neighborhood Hits	25
SwissProt Accessions	Q16538, Q16664, Q59EH5, Q66K56	Gene names	GPR162, GRCA
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 162 (Gene-rich cluster gene A protein).

GP162_MOUSE
θ value	0.365318 (rank : 14)	NC score	0.113460 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	242	Shared Neighborhood Hits	25
SwissProt Accessions	Q3UN16, O88835	Gene names	Gpr162
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 162.

GP101_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.061005 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	916	Shared Neighborhood Hits	37
SwissProt Accessions	Q80T62, Q3UUI9	Gene names	Gpr101
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 101.

GP153_MOUSE
θ value	0.47712 (rank : 16)	NC score	0.104475 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K0Z9, Q80T37, Q8CFK0	Gene names	Gpr153, Pgr1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

OPSX_MOUSE
θ value	0.47712 (rank : 17)	NC score	0.071445 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	837	Shared Neighborhood Hits	33
SwissProt Accessions	O35214	Gene names	Rrh
Domain Architecture
Description	Visual pigment-like receptor peropsin.

ADA1B_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.063719 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	966	Shared Neighborhood Hits	40
SwissProt Accessions	P97717	Gene names	Adra1b
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).

EDG7_HUMAN
θ value	0.813845 (rank : 19)	NC score	0.053709 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	581	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBY5	Gene names	EDG7, LPA3
Domain Architecture
Description	Lysophosphatidic acid receptor Edg-7 (LPA receptor 3) (LPA-3).

OPSX_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.071486 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	883	Shared Neighborhood Hits	36
SwissProt Accessions	O14718, Q7RTS4	Gene names	RRH
Domain Architecture
Description	Visual pigment-like receptor peropsin.

5HT7R_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.060952 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	848	Shared Neighborhood Hits	38
SwissProt Accessions	P34969, P78336, P78372, P78516	Gene names	HTR7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

5HT7R_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.061305 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	823	Shared Neighborhood Hits	38
SwissProt Accessions	P32304	Gene names	Htr7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

ADA1A_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.052599 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	943	Shared Neighborhood Hits	38
SwissProt Accessions	P35348, O60451, Q13675, Q13729, Q6RUJ4, Q6RUJ5, Q6RUJ7, Q6RUJ8, Q6RUJ9, Q9UD63	Gene names	ADRA1A, ADRA1C
Domain Architecture
Description	Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A- adrenoreceptor) (Alpha-1C adrenergic receptor) (Alpha adrenergic receptor 1c).

ADA1A_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.054031 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	940	Shared Neighborhood Hits	39
SwissProt Accessions	P97718, O54913	Gene names	Adra1a, Adra1c
Domain Architecture
Description	Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A- adrenoreceptor) (Alpha-1C adrenergic receptor).

ADA1B_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.062135 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	978	Shared Neighborhood Hits	40
SwissProt Accessions	P35368	Gene names	ADRA1B
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).

DDX24_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.027558 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

BTBD7_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.030286 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

CNR2_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.060884 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	666	Shared Neighborhood Hits	38
SwissProt Accessions	P34972	Gene names	CNR2
Domain Architecture
Description	Cannabinoid receptor 2 (CB2) (CB-2) (CX5).

CT151_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.037967 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	382	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

PLP2_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.042373 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1Q7, Q3U4I3	Gene names	Plp2
Domain Architecture	No domain graphic available
Description	Proteolipid protein 2.

ADA2B_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.054560 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	891	Shared Neighborhood Hits	38
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).

ERCC4_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.033139 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZD4, O54810, Q8R0I3	Gene names	Ercc4
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4).

LEO1_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.016969 (rank : 73)
Query Neighborhood Hits	68	Target Neighborhood Hits	946	Shared Neighborhood Hits	7
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

RPGR_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.022096 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

AFF4_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.019118 (rank : 71)
Query Neighborhood Hits	68	Target Neighborhood Hits	611	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

LT4R1_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.037068 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	568	Shared Neighborhood Hits	33
SwissProt Accessions	O88855	Gene names	Ltb4r, Bltr, Ltb4r1
Domain Architecture
Description	Leukotriene B4 receptor 1 (LTB4-R 1).

OPSB_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.061357 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	706	Shared Neighborhood Hits	35
SwissProt Accessions	P03999, Q13877	Gene names	OPN1SW, BCP
Domain Architecture
Description	Blue-sensitive opsin (BOP) (Blue cone photoreceptor pigment).

OPSB_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.059552 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	784	Shared Neighborhood Hits	35
SwissProt Accessions	P51491, Q548Z8	Gene names	Opn1sw, Bcp
Domain Architecture
Description	Blue-sensitive opsin (BOP) (Blue cone photoreceptor pigment) (Short wavelength-sensitive cone opsin) (S opsin).

STA13_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.015618 (rank : 76)
Query Neighborhood Hits	68	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

ADA2B_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.054048 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	881	Shared Neighborhood Hits	38
SwissProt Accessions	P18089, Q4TUH9, Q53RF2, Q9BZK0	Gene names	ADRA2B
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor) (Alpha-2 adrenergic receptor subtype C2).

BRCA1_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.017692 (rank : 72)
Query Neighborhood Hits	68	Target Neighborhood Hits	436	Shared Neighborhood Hits	4
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

OPSD_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.062811 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	867	Shared Neighborhood Hits	36
SwissProt Accessions	P08100, Q16414	Gene names	RHO, OPN2
Domain Architecture
Description	Rhodopsin (Opsin-2).

PSYR_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.028246 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	744	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IYL9, O75819	Gene names	GPR65, TDAG8
Domain Architecture
Description	Psychosine receptor (G-protein coupled receptor 65) (T cell death- associated protein 8).

CYLC1_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.024750 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	408	Shared Neighborhood Hits	8
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

MYO15_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.006908 (rank : 84)
Query Neighborhood Hits	68	Target Neighborhood Hits	671	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CRSP2_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.021830 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	380	Shared Neighborhood Hits	4
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

GP135_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.051935 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	669	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZ08, Q7Z604, Q86SM3, Q8NH39	Gene names	GPR135
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 135.

GP135_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.049805 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	671	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TQP2	Gene names	Gpr135
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 135.

P2RY5_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.028353 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	630	Shared Neighborhood Hits	34
SwissProt Accessions	P43657, O15133, Q3KPF5, Q5VW44, Q7Z3S0, Q7Z3S6	Gene names	P2RY5
Domain Architecture
Description	P2Y purinoceptor 5 (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor).

PXK_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.016754 (rank : 74)
Query Neighborhood Hits	68	Target Neighborhood Hits	320	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SALL1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.001584 (rank : 89)
Query Neighborhood Hits	68	Target Neighborhood Hits	821	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSC2, Q99881, Q9NSC3, Q9P1R0	Gene names	SALL1, SAL1
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein SALL1) (Spalt-like transcription factor 1) (HSal1).

STK10_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.002609 (rank : 88)
Query Neighborhood Hits	68	Target Neighborhood Hits	1921	Shared Neighborhood Hits	8
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

CNR1_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.053663 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	751	Shared Neighborhood Hits	34
SwissProt Accessions	P21554, Q13949, Q495Z0, Q4PLI4, Q4VBM6, Q5UB37, Q9UNN0	Gene names	CNR1, CNR
Domain Architecture
Description	Cannabinoid receptor 1 (CB1) (CB-R) (CANN6).

CNR1_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.052750 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	745	Shared Neighborhood Hits	33
SwissProt Accessions	P47746, Q5SF33	Gene names	Cnr1
Domain Architecture
Description	Cannabinoid receptor 1 (CB1) (CB-R) (Brain-type cannabinoid receptor).

GP153_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.075003 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	332	Shared Neighborhood Hits	26
SwissProt Accessions	Q6NV75, Q5TGR5, Q6AHW8, Q86SP8	Gene names	GPR153, PGR1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

MLL3_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.007355 (rank : 83)
Query Neighborhood Hits	68	Target Neighborhood Hits	1644	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

OR2L5_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.012206 (rank : 79)
Query Neighborhood Hits	68	Target Neighborhood Hits	771	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NG80, Q6IF04	Gene names	OR2L5, OR2L11
Domain Architecture
Description	Olfactory receptor 2L5 (Olfactory receptor OR1-53).

TITIN_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.000148 (rank : 90)
Query Neighborhood Hits	68	Target Neighborhood Hits	2923	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ACHB4_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.003893 (rank : 86)
Query Neighborhood Hits	68	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R493, Q8VI06	Gene names	Chrnb4, Acrb4
Domain Architecture	No domain graphic available
Description	Neuronal acetylcholine receptor protein subunit beta-4 precursor.

AFAD_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.010212 (rank : 80)
Query Neighborhood Hits	68	Target Neighborhood Hits	689	Shared Neighborhood Hits	9
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

CAC1B_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.004564 (rank : 85)
Query Neighborhood Hits	68	Target Neighborhood Hits	351	Shared Neighborhood Hits	2
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CASP1_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.009021 (rank : 82)
Query Neighborhood Hits	68	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P29466, Q9UCN3	Gene names	CASP1, IL1BC, IL1BCE
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

MUC1_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.002900 (rank : 87)
Query Neighborhood Hits	68	Target Neighborhood Hits	975	Shared Neighborhood Hits	6
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MYC_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.009945 (rank : 81)
Query Neighborhood Hits	68	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

PLCB_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.013792 (rank : 78)
Query Neighborhood Hits	68	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K3K7	Gene names	Agpat2
Domain Architecture	No domain graphic available
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase beta (EC 2.3.1.51) (1- AGP acyltransferase 2) (1-AGPAT 2) (Lysophosphatidic acid acyltransferase-beta) (LPAAT-beta) (1-acylglycerol-3-phosphate O- acyltransferase 2).

SGOL1_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.016115 (rank : 75)
Query Neighborhood Hits	68	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

VIAAT_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.031687 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H598, Q8N489	Gene names	SLC32A1, VGAT, VIAAT
Domain Architecture
Description	Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Vesicular GABA transporter) (hVIAAT) (Solute carrier family 32 member 1).

VIAAT_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.033289 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O35633	Gene names	Slc32a1, Vgat, Viaat
Domain Architecture
Description	Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Vesicular GABA transporter) (mVIAAT) (mVGAT) (Solute carrier family 32 member 1).

5HT1B_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.050530 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	865	Shared Neighborhood Hits	37
SwissProt Accessions	P28222, Q4VAY7	Gene names	HTR1B, HTR1DB
Domain Architecture
Description	5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5- HT1B) (5-HT-1D-beta) (Serotonin 1D beta receptor) (S12).

5HT1B_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.050531 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	861	Shared Neighborhood Hits	37
SwissProt Accessions	P28334	Gene names	Htr1b, 5ht1b
Domain Architecture
Description	5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5- HT1B).

5HT1E_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.053681 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	759	Shared Neighborhood Hits	35
SwissProt Accessions	P28566, Q9P1Y1	Gene names	HTR1E
Domain Architecture
Description	5-hydroxytryptamine 1E receptor (5-HT-1E) (Serotonin receptor 1E) (5- HT1E) (S31).

5HT1F_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.050119 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	821	Shared Neighborhood Hits	37
SwissProt Accessions	P30939	Gene names	HTR1F, HTR1EL
Domain Architecture
Description	5-hydroxytryptamine 1F receptor (5-HT-1F) (Serotonin receptor 1F).

5HT5A_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.050429 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	578	Shared Neighborhood Hits	36
SwissProt Accessions	P47898	Gene names	HTR5A
Domain Architecture
Description	5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5- HT-5).

5HT5A_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.051412 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	615	Shared Neighborhood Hits	35
SwissProt Accessions	P30966	Gene names	Htr5a, 5ht5a
Domain Architecture
Description	5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5- HT-5).

ADA1D_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.050645 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	874	Shared Neighborhood Hits	37
SwissProt Accessions	P97714, Q61619	Gene names	Adra1d, Adra1a, Gpcr8
Domain Architecture
Description	Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D- adrenoreceptor) (Alpha-1A adrenergic receptor).

ADA2A_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.053187 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	911	Shared Neighborhood Hits	37
SwissProt Accessions	P08913, Q2XN99, Q86TH8, Q9BZK1	Gene names	ADRA2A, ADRA2R, ADRAR
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR) (Alpha-2 adrenergic receptor subtype C10).

EDG8_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.057866 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	521	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H228, Q6NW11	Gene names	EDG8
Domain Architecture	No domain graphic available
Description	Sphingosine 1-phosphate receptor Edg-8 (Endothelial differentiation sphingolipid G-protein-coupled receptor 8) (Sphingosine 1-phosphate receptor 5) (S1P5).

EDG8_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.053301 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	520	Shared Neighborhood Hits	27
SwissProt Accessions	Q91X56, Q99MN8	Gene names	Edg8, Lpb4
Domain Architecture	No domain graphic available
Description	Sphingosine 1-phosphate receptor Edg-8 (Endothelial differentiation sphingolipid G-protein-coupled receptor 8) (Sphingosine 1-phosphate receptor 5) (S1P5) (Lysophospholipid receptor B4).

GP101_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.059237 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	913	Shared Neighborhood Hits	40
SwissProt Accessions	Q96P66, Q8NG93	Gene names	GPR101
Domain Architecture
Description	Probable G-protein coupled receptor 101.

GP161_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.056775 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	690	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N6U8, O75963, Q5TGK0, Q5TGK1	Gene names	GPR161
Domain Architecture
Description	Probable G-protein coupled receptor 161 (G-protein coupled receptor RE2).

GPBAR_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.081572 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDU6	Gene names	GPBAR1, TGR5
Domain Architecture	No domain graphic available
Description	G-protein coupled bile acid receptor 1 (Membrane-type receptor for bile acids) (M-BAR) (hGPCR19) (BG37) (hBG37).

OPN3_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.061113 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	679	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H1Y3, Q8IX08, Q9Y344	Gene names	OPN3, ECPN
Domain Architecture
Description	Opsin-3 (Encephalopsin) (Panopsin).

OPN3_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.056992 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	782	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WUK7, Q3V0X3	Gene names	Opn3, Ecpn
Domain Architecture
Description	Opsin-3 (Encephalopsin) (Panopsin).

OPN5_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.067474 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	604	Shared Neighborhood Hits	34
SwissProt Accessions	Q6U736, Q5T5B9, Q5T886, Q7Z603, Q86SL5	Gene names	OPN5, GPR136, PGR12, TMEM13
Domain Architecture	No domain graphic available
Description	Opsin-5 (Neuropsin) (G-protein coupled receptor 136) (G-protein coupled receptor PGR12) (Transmembrane protein 13).

OPN5_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.063770 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	595	Shared Neighborhood Hits	31
SwissProt Accessions	Q6VZZ7, Q7TQP1, Q80T51, Q8BYI2	Gene names	Opn5, Gpr136, Pgr12
Domain Architecture	No domain graphic available
Description	Opsin-5 (Neuropsin) (G-protein coupled receptor 136) (G-protein coupled receptor PGR12).

OPSD_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.056817 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	864	Shared Neighborhood Hits	36
SwissProt Accessions	P15409	Gene names	Rho
Domain Architecture
Description	Rhodopsin.

OPSG_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.057673 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	707	Shared Neighborhood Hits	31
SwissProt Accessions	P04001	Gene names	OPN1MW, GCP
Domain Architecture
Description	Green-sensitive opsin (Green cone photoreceptor pigment).

OPSG_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.056908 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	717	Shared Neighborhood Hits	31
SwissProt Accessions	O35599, Q548Z4	Gene names	Opn1mw, Gcp
Domain Architecture
Description	Green-sensitive opsin (Green cone photoreceptor pigment) (Medium wavelength-sensitive cone opsin) (M opsin).

OPSR_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.056485 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	729	Shared Neighborhood Hits	32
SwissProt Accessions	P04000	Gene names	OPN1LW, RCP
Domain Architecture
Description	Red-sensitive opsin (Red cone photoreceptor pigment).

PE2R4_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.055975 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	525	Shared Neighborhood Hits	25
SwissProt Accessions	P32240	Gene names	Ptger4, Ptgerep4
Domain Architecture
Description	Prostaglandin E2 receptor, EP4 subtype (Prostanoid EP4 receptor) (PGE receptor, EP4 subtype).

Hits sorted by NC score

GP149_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	68	Target Neighborhood Hits	68	Shared Neighborhood Hits	68
SwissProt Accessions	Q86SP6	Gene names	GPR149, PGR10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

GP149_MOUSE
NC score	0.963939 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	68	Target Neighborhood Hits	61	Shared Neighborhood Hits	18
SwissProt Accessions	Q3UVY1, Q3TMB1, Q80T52, Q8BXA3, Q8BZC0	Gene names	Gpr149, Pgr10
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 149 (G-protein coupled receptor PGR10).

RGR_MOUSE
NC score	0.179610 (rank : 3)	θ value	0.00102713 (rank : 4)
Query Neighborhood Hits	68	Target Neighborhood Hits	209	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z2B3	Gene names	Rgr
Domain Architecture
Description	RPE-retinal G protein-coupled receptor.

RGR_HUMAN
NC score	0.154312 (rank : 4)	θ value	0.0148317 (rank : 6)
Query Neighborhood Hits	68	Target Neighborhood Hits	227	Shared Neighborhood Hits	25
SwissProt Accessions	P47804, Q96FC5	Gene names	RGR
Domain Architecture
Description	RPE-retinal G protein-coupled receptor.

GPBAR_MOUSE
NC score	0.125864 (rank : 5)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	68	Target Neighborhood Hits	155	Shared Neighborhood Hits	24
SwissProt Accessions	Q80SS6	Gene names	Gpbar1, Tgr5
Domain Architecture	No domain graphic available
Description	G-protein coupled bile acid receptor 1 (Membrane-type receptor for bile acids) (M-BAR).

GP162_HUMAN
NC score	0.113544 (rank : 6)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	68	Target Neighborhood Hits	244	Shared Neighborhood Hits	25
SwissProt Accessions	Q16538, Q16664, Q59EH5, Q66K56	Gene names	GPR162, GRCA
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 162 (Gene-rich cluster gene A protein).

GP162_MOUSE
NC score	0.113460 (rank : 7)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	68	Target Neighborhood Hits	242	Shared Neighborhood Hits	25
SwissProt Accessions	Q3UN16, O88835	Gene names	Gpr162
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 162.

GP153_MOUSE
NC score	0.104475 (rank : 8)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	68	Target Neighborhood Hits	204	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K0Z9, Q80T37, Q8CFK0	Gene names	Gpr153, Pgr1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

OPN4_MOUSE
NC score	0.087963 (rank : 9)	θ value	0.00134147 (rank : 5)
Query Neighborhood Hits	68	Target Neighborhood Hits	916	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QXZ9	Gene names	Opn4, Mop, Mopn
Domain Architecture
Description	Melanopsin (Opsin-4).

OPN4_HUMAN
NC score	0.087204 (rank : 10)	θ value	0.000786445 (rank : 3)
Query Neighborhood Hits	68	Target Neighborhood Hits	923	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UHM6, Q2PP22, Q8NGQ9	Gene names	OPN4, MOP
Domain Architecture
Description	Melanopsin (Opsin-4).

GPBAR_HUMAN
NC score	0.081572 (rank : 11)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	68	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDU6	Gene names	GPBAR1, TGR5
Domain Architecture	No domain graphic available
Description	G-protein coupled bile acid receptor 1 (Membrane-type receptor for bile acids) (M-BAR) (hGPCR19) (BG37) (hBG37).

GP153_HUMAN
NC score	0.075003 (rank : 12)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	68	Target Neighborhood Hits	332	Shared Neighborhood Hits	26
SwissProt Accessions	Q6NV75, Q5TGR5, Q6AHW8, Q86SP8	Gene names	GPR153, PGR1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 153 (G-protein coupled receptor PGR1).

OPSX_HUMAN
NC score	0.071486 (rank : 13)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	68	Target Neighborhood Hits	883	Shared Neighborhood Hits	36
SwissProt Accessions	O14718, Q7RTS4	Gene names	RRH
Domain Architecture
Description	Visual pigment-like receptor peropsin.

OPSX_MOUSE
NC score	0.071445 (rank : 14)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	68	Target Neighborhood Hits	837	Shared Neighborhood Hits	33
SwissProt Accessions	O35214	Gene names	Rrh
Domain Architecture
Description	Visual pigment-like receptor peropsin.

OPN5_HUMAN
NC score	0.067474 (rank : 15)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	68	Target Neighborhood Hits	604	Shared Neighborhood Hits	34
SwissProt Accessions	Q6U736, Q5T5B9, Q5T886, Q7Z603, Q86SL5	Gene names	OPN5, GPR136, PGR12, TMEM13
Domain Architecture	No domain graphic available
Description	Opsin-5 (Neuropsin) (G-protein coupled receptor 136) (G-protein coupled receptor PGR12) (Transmembrane protein 13).

5HT1A_MOUSE
NC score	0.063869 (rank : 16)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	68	Target Neighborhood Hits	891	Shared Neighborhood Hits	39
SwissProt Accessions	Q64264, Q60956, Q61617	Gene names	Htr1a, Gpcr18
Domain Architecture
Description	5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5- HT1A).

OPN5_MOUSE
NC score	0.063770 (rank : 17)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	68	Target Neighborhood Hits	595	Shared Neighborhood Hits	31
SwissProt Accessions	Q6VZZ7, Q7TQP1, Q80T51, Q8BYI2	Gene names	Opn5, Gpr136, Pgr12
Domain Architecture	No domain graphic available
Description	Opsin-5 (Neuropsin) (G-protein coupled receptor 136) (G-protein coupled receptor PGR12).

ADA1B_MOUSE
NC score	0.063719 (rank : 18)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	68	Target Neighborhood Hits	966	Shared Neighborhood Hits	40
SwissProt Accessions	P97717	Gene names	Adra1b
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).

5HT1A_HUMAN
NC score	0.063333 (rank : 19)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	68	Target Neighborhood Hits	887	Shared Neighborhood Hits	39
SwissProt Accessions	P08908, Q6LAE7	Gene names	HTR1A
Domain Architecture
Description	5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5- HT1A) (G-21).

OPSD_HUMAN
NC score	0.062811 (rank : 20)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	68	Target Neighborhood Hits	867	Shared Neighborhood Hits	36
SwissProt Accessions	P08100, Q16414	Gene names	RHO, OPN2
Domain Architecture
Description	Rhodopsin (Opsin-2).

ADA1B_HUMAN
NC score	0.062135 (rank : 21)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	68	Target Neighborhood Hits	978	Shared Neighborhood Hits	40
SwissProt Accessions	P35368	Gene names	ADRA1B
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).

OPSB_HUMAN
NC score	0.061357 (rank : 22)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	68	Target Neighborhood Hits	706	Shared Neighborhood Hits	35
SwissProt Accessions	P03999, Q13877	Gene names	OPN1SW, BCP
Domain Architecture
Description	Blue-sensitive opsin (BOP) (Blue cone photoreceptor pigment).

5HT7R_MOUSE
NC score	0.061305 (rank : 23)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	68	Target Neighborhood Hits	823	Shared Neighborhood Hits	38
SwissProt Accessions	P32304	Gene names	Htr7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

OPN3_HUMAN
NC score	0.061113 (rank : 24)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	68	Target Neighborhood Hits	679	Shared Neighborhood Hits	32
SwissProt Accessions	Q9H1Y3, Q8IX08, Q9Y344	Gene names	OPN3, ECPN
Domain Architecture
Description	Opsin-3 (Encephalopsin) (Panopsin).

GP101_MOUSE
NC score	0.061005 (rank : 25)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	68	Target Neighborhood Hits	916	Shared Neighborhood Hits	37
SwissProt Accessions	Q80T62, Q3UUI9	Gene names	Gpr101
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 101.

5HT7R_HUMAN
NC score	0.060952 (rank : 26)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	68	Target Neighborhood Hits	848	Shared Neighborhood Hits	38
SwissProt Accessions	P34969, P78336, P78372, P78516	Gene names	HTR7
Domain Architecture
Description	5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT- X) (5HT7).

MCHR2_HUMAN
NC score	0.060907 (rank : 27)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	68	Target Neighborhood Hits	562	Shared Neighborhood Hits	30
SwissProt Accessions	Q969V1, Q6Q377, Q9BXA8	Gene names	MCHR2, GPR145, SLT
Domain Architecture
Description	Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCHR-2) (MCH-R2) (MCH2R) (MCH-2R) (MCH2) (G-protein coupled receptor 145) (GPRv17).

CNR2_HUMAN
NC score	0.060884 (rank : 28)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	68	Target Neighborhood Hits	666	Shared Neighborhood Hits	38
SwissProt Accessions	P34972	Gene names	CNR2
Domain Architecture
Description	Cannabinoid receptor 2 (CB2) (CB-2) (CX5).

OPSB_MOUSE
NC score	0.059552 (rank : 29)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	68	Target Neighborhood Hits	784	Shared Neighborhood Hits	35
SwissProt Accessions	P51491, Q548Z8	Gene names	Opn1sw, Bcp
Domain Architecture
Description	Blue-sensitive opsin (BOP) (Blue cone photoreceptor pigment) (Short wavelength-sensitive cone opsin) (S opsin).

GP101_HUMAN
NC score	0.059237 (rank : 30)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	68	Target Neighborhood Hits	913	Shared Neighborhood Hits	40
SwissProt Accessions	Q96P66, Q8NG93	Gene names	GPR101
Domain Architecture
Description	Probable G-protein coupled receptor 101.

EDG8_HUMAN
NC score	0.057866 (rank : 31)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	68	Target Neighborhood Hits	521	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H228, Q6NW11	Gene names	EDG8
Domain Architecture	No domain graphic available
Description	Sphingosine 1-phosphate receptor Edg-8 (Endothelial differentiation sphingolipid G-protein-coupled receptor 8) (Sphingosine 1-phosphate receptor 5) (S1P5).

OPSG_HUMAN
NC score	0.057673 (rank : 32)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	68	Target Neighborhood Hits	707	Shared Neighborhood Hits	31
SwissProt Accessions	P04001	Gene names	OPN1MW, GCP
Domain Architecture
Description	Green-sensitive opsin (Green cone photoreceptor pigment).

OPN3_MOUSE
NC score	0.056992 (rank : 33)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	68	Target Neighborhood Hits	782	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WUK7, Q3V0X3	Gene names	Opn3, Ecpn
Domain Architecture
Description	Opsin-3 (Encephalopsin) (Panopsin).

OPSG_MOUSE
NC score	0.056908 (rank : 34)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	68	Target Neighborhood Hits	717	Shared Neighborhood Hits	31
SwissProt Accessions	O35599, Q548Z4	Gene names	Opn1mw, Gcp
Domain Architecture
Description	Green-sensitive opsin (Green cone photoreceptor pigment) (Medium wavelength-sensitive cone opsin) (M opsin).

OPSD_MOUSE
NC score	0.056817 (rank : 35)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	68	Target Neighborhood Hits	864	Shared Neighborhood Hits	36
SwissProt Accessions	P15409	Gene names	Rho
Domain Architecture
Description	Rhodopsin.

GP161_HUMAN
NC score	0.056775 (rank : 36)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	68	Target Neighborhood Hits	690	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N6U8, O75963, Q5TGK0, Q5TGK1	Gene names	GPR161
Domain Architecture
Description	Probable G-protein coupled receptor 161 (G-protein coupled receptor RE2).

OPSR_HUMAN
NC score	0.056485 (rank : 37)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	68	Target Neighborhood Hits	729	Shared Neighborhood Hits	32
SwissProt Accessions	P04000	Gene names	OPN1LW, RCP
Domain Architecture
Description	Red-sensitive opsin (Red cone photoreceptor pigment).

PE2R4_MOUSE
NC score	0.055975 (rank : 38)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	68	Target Neighborhood Hits	525	Shared Neighborhood Hits	25
SwissProt Accessions	P32240	Gene names	Ptger4, Ptgerep4
Domain Architecture
Description	Prostaglandin E2 receptor, EP4 subtype (Prostanoid EP4 receptor) (PGE receptor, EP4 subtype).

EDG7_MOUSE
NC score	0.055438 (rank : 39)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	68	Target Neighborhood Hits	602	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EQ31	Gene names	Edg7, Lpa3
Domain Architecture
Description	Lysophosphatidic acid receptor Edg-7 (LPA receptor 3) (LPA-3).

ADA2B_MOUSE
NC score	0.054560 (rank : 40)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	68	Target Neighborhood Hits	891	Shared Neighborhood Hits	38
SwissProt Accessions	P30545	Gene names	Adra2b
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor).

ADA2B_HUMAN
NC score	0.054048 (rank : 41)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	68	Target Neighborhood Hits	881	Shared Neighborhood Hits	38
SwissProt Accessions	P18089, Q4TUH9, Q53RF2, Q9BZK0	Gene names	ADRA2B
Domain Architecture
Description	Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2B adrenoreceptor) (Alpha-2 adrenergic receptor subtype C2).

ADA1A_MOUSE
NC score	0.054031 (rank : 42)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	68	Target Neighborhood Hits	940	Shared Neighborhood Hits	39
SwissProt Accessions	P97718, O54913	Gene names	Adra1a, Adra1c
Domain Architecture
Description	Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A- adrenoreceptor) (Alpha-1C adrenergic receptor).

EDG7_HUMAN
NC score	0.053709 (rank : 43)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	68	Target Neighborhood Hits	581	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UBY5	Gene names	EDG7, LPA3
Domain Architecture
Description	Lysophosphatidic acid receptor Edg-7 (LPA receptor 3) (LPA-3).

5HT1E_HUMAN
NC score	0.053681 (rank : 44)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	68	Target Neighborhood Hits	759	Shared Neighborhood Hits	35
SwissProt Accessions	P28566, Q9P1Y1	Gene names	HTR1E
Domain Architecture
Description	5-hydroxytryptamine 1E receptor (5-HT-1E) (Serotonin receptor 1E) (5- HT1E) (S31).

CNR1_HUMAN
NC score	0.053663 (rank : 45)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	68	Target Neighborhood Hits	751	Shared Neighborhood Hits	34
SwissProt Accessions	P21554, Q13949, Q495Z0, Q4PLI4, Q4VBM6, Q5UB37, Q9UNN0	Gene names	CNR1, CNR
Domain Architecture
Description	Cannabinoid receptor 1 (CB1) (CB-R) (CANN6).

EDG8_MOUSE
NC score	0.053301 (rank : 46)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	68	Target Neighborhood Hits	520	Shared Neighborhood Hits	27
SwissProt Accessions	Q91X56, Q99MN8	Gene names	Edg8, Lpb4
Domain Architecture	No domain graphic available
Description	Sphingosine 1-phosphate receptor Edg-8 (Endothelial differentiation sphingolipid G-protein-coupled receptor 8) (Sphingosine 1-phosphate receptor 5) (S1P5) (Lysophospholipid receptor B4).

ADA2A_HUMAN
NC score	0.053187 (rank : 47)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	68	Target Neighborhood Hits	911	Shared Neighborhood Hits	37
SwissProt Accessions	P08913, Q2XN99, Q86TH8, Q9BZK1	Gene names	ADRA2A, ADRA2R, ADRAR
Domain Architecture
Description	Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2A adrenoreceptor) (Alpha-2AAR) (Alpha-2 adrenergic receptor subtype C10).

CNR1_MOUSE
NC score	0.052750 (rank : 48)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	68	Target Neighborhood Hits	745	Shared Neighborhood Hits	33
SwissProt Accessions	P47746, Q5SF33	Gene names	Cnr1
Domain Architecture
Description	Cannabinoid receptor 1 (CB1) (CB-R) (Brain-type cannabinoid receptor).

ADA1A_HUMAN
NC score	0.052599 (rank : 49)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	68	Target Neighborhood Hits	943	Shared Neighborhood Hits	38
SwissProt Accessions	P35348, O60451, Q13675, Q13729, Q6RUJ4, Q6RUJ5, Q6RUJ7, Q6RUJ8, Q6RUJ9, Q9UD63	Gene names	ADRA1A, ADRA1C
Domain Architecture
Description	Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A- adrenoreceptor) (Alpha-1C adrenergic receptor) (Alpha adrenergic receptor 1c).

GP135_HUMAN
NC score	0.051935 (rank : 50)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	68	Target Neighborhood Hits	669	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZ08, Q7Z604, Q86SM3, Q8NH39	Gene names	GPR135
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 135.

5HT5A_MOUSE
NC score	0.051412 (rank : 51)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	68	Target Neighborhood Hits	615	Shared Neighborhood Hits	35
SwissProt Accessions	P30966	Gene names	Htr5a, 5ht5a
Domain Architecture
Description	5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5- HT-5).

ADA1D_MOUSE
NC score	0.050645 (rank : 52)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	68	Target Neighborhood Hits	874	Shared Neighborhood Hits	37
SwissProt Accessions	P97714, Q61619	Gene names	Adra1d, Adra1a, Gpcr8
Domain Architecture
Description	Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D- adrenoreceptor) (Alpha-1A adrenergic receptor).

5HT1B_MOUSE
NC score	0.050531 (rank : 53)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	68	Target Neighborhood Hits	861	Shared Neighborhood Hits	37
SwissProt Accessions	P28334	Gene names	Htr1b, 5ht1b
Domain Architecture
Description	5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5- HT1B).

5HT1B_HUMAN
NC score	0.050530 (rank : 54)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	68	Target Neighborhood Hits	865	Shared Neighborhood Hits	37
SwissProt Accessions	P28222, Q4VAY7	Gene names	HTR1B, HTR1DB
Domain Architecture
Description	5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5- HT1B) (5-HT-1D-beta) (Serotonin 1D beta receptor) (S12).

5HT5A_HUMAN
NC score	0.050429 (rank : 55)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	68	Target Neighborhood Hits	578	Shared Neighborhood Hits	36
SwissProt Accessions	P47898	Gene names	HTR5A
Domain Architecture
Description	5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5- HT-5).

5HT1F_HUMAN
NC score	0.050119 (rank : 56)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	68	Target Neighborhood Hits	821	Shared Neighborhood Hits	37
SwissProt Accessions	P30939	Gene names	HTR1F, HTR1EL
Domain Architecture
Description	5-hydroxytryptamine 1F receptor (5-HT-1F) (Serotonin receptor 1F).

GP135_MOUSE
NC score	0.049805 (rank : 57)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	68	Target Neighborhood Hits	671	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TQP2	Gene names	Gpr135
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 135.

PLP2_MOUSE
NC score	0.042373 (rank : 58)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	68	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1Q7, Q3U4I3	Gene names	Plp2
Domain Architecture	No domain graphic available
Description	Proteolipid protein 2.

CT151_HUMAN
NC score	0.037967 (rank : 59)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	68	Target Neighborhood Hits	382	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NC74, Q8N4Z9, Q9BR75, Q9H0Y9	Gene names	C20orf151
Domain Architecture
Description	Uncharacterized protein C20orf151.

LT4R1_MOUSE
NC score	0.037068 (rank : 60)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	68	Target Neighborhood Hits	568	Shared Neighborhood Hits	33
SwissProt Accessions	O88855	Gene names	Ltb4r, Bltr, Ltb4r1
Domain Architecture
Description	Leukotriene B4 receptor 1 (LTB4-R 1).

VIAAT_MOUSE
NC score	0.033289 (rank : 61)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	68	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O35633	Gene names	Slc32a1, Vgat, Viaat
Domain Architecture
Description	Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Vesicular GABA transporter) (mVIAAT) (mVGAT) (Solute carrier family 32 member 1).

ERCC4_MOUSE
NC score	0.033139 (rank : 62)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	68	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZD4, O54810, Q8R0I3	Gene names	Ercc4
Domain Architecture
Description	DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4).

VIAAT_HUMAN
NC score	0.031687 (rank : 63)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	68	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H598, Q8N489	Gene names	SLC32A1, VGAT, VIAAT
Domain Architecture
Description	Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Vesicular GABA transporter) (hVIAAT) (Solute carrier family 32 member 1).

BTBD7_HUMAN
NC score	0.030286 (rank : 64)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	68	Target Neighborhood Hits	176	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P203, Q69Z05, Q7Z308, Q86TS0, Q9HAA4, Q9NVM0	Gene names	BTBD7, KIAA1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

P2RY5_HUMAN
NC score	0.028353 (rank : 65)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	68	Target Neighborhood Hits	630	Shared Neighborhood Hits	34
SwissProt Accessions	P43657, O15133, Q3KPF5, Q5VW44, Q7Z3S0, Q7Z3S6	Gene names	P2RY5
Domain Architecture
Description	P2Y purinoceptor 5 (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor).

PSYR_HUMAN
NC score	0.028246 (rank : 66)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	68	Target Neighborhood Hits	744	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IYL9, O75819	Gene names	GPR65, TDAG8
Domain Architecture
Description	Psychosine receptor (G-protein coupled receptor 65) (T cell death- associated protein 8).

DDX24_HUMAN
NC score	0.027558 (rank : 67)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	68	Target Neighborhood Hits	190	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

CYLC1_HUMAN
NC score	0.024750 (rank : 68)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	68	Target Neighborhood Hits	408	Shared Neighborhood Hits	8
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

RPGR_HUMAN
NC score	0.022096 (rank : 69)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	68	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

CRSP2_HUMAN
NC score	0.021830 (rank : 70)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	68	Target Neighborhood Hits	380	Shared Neighborhood Hits	4
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

AFF4_HUMAN
NC score	0.019118 (rank : 71)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	68	Target Neighborhood Hits	611	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

BRCA1_MOUSE
NC score	0.017692 (rank : 72)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	68	Target Neighborhood Hits	436	Shared Neighborhood Hits	4
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

LEO1_MOUSE
NC score	0.016969 (rank : 73)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	68	Target Neighborhood Hits	946	Shared Neighborhood Hits	7
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PXK_MOUSE
NC score	0.016754 (rank : 74)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	68	Target Neighborhood Hits	320	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BX57, Q3TD60, Q3TEL7, Q3TZZ1, Q3U197, Q3U773, Q3UCS5, Q4FBH7, Q91WB6	Gene names	Pxk
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SGOL1_HUMAN
NC score	0.016115 (rank : 75)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	68	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q5FBB7, Q588H5, Q5FBB4, Q5FBB5, Q5FBB6, Q5FBB8, Q8N579, Q8WVL0, Q9BVA8, Q9H275	Gene names	SGOL1, SGO1
Domain Architecture	No domain graphic available
Description	Shugoshin-like 1 (hSgo1) (Serologically defined breast cancer antigen NY-BR-85).

STA13_HUMAN
NC score	0.015618 (rank : 76)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	68	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

OR2LD_HUMAN
NC score	0.014041 (rank : 77)	θ value	0.0193708 (rank : 7)
Query Neighborhood Hits	68	Target Neighborhood Hits	760	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N349, Q5VUR5	Gene names	OR2L13, OR2L14
Domain Architecture
Description	Olfactory receptor 2L13.

PLCB_MOUSE
NC score	0.013792 (rank : 78)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	68	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K3K7	Gene names	Agpat2
Domain Architecture	No domain graphic available
Description	1-acyl-sn-glycerol-3-phosphate acyltransferase beta (EC 2.3.1.51) (1- AGP acyltransferase 2) (1-AGPAT 2) (Lysophosphatidic acid acyltransferase-beta) (LPAAT-beta) (1-acylglycerol-3-phosphate O- acyltransferase 2).

OR2L5_HUMAN
NC score	0.012206 (rank : 79)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	68	Target Neighborhood Hits	771	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NG80, Q6IF04	Gene names	OR2L5, OR2L11
Domain Architecture
Description	Olfactory receptor 2L5 (Olfactory receptor OR1-53).

AFAD_HUMAN
NC score	0.010212 (rank : 80)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	68	Target Neighborhood Hits	689	Shared Neighborhood Hits	9
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

MYC_MOUSE
NC score	0.009945 (rank : 81)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	68	Target Neighborhood Hits	125	Shared Neighborhood Hits	2
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

CASP1_HUMAN
NC score	0.009021 (rank : 82)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	68	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	P29466, Q9UCN3	Gene names	CASP1, IL1BC, IL1BCE
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

MLL3_HUMAN
NC score	0.007355 (rank : 83)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	68	Target Neighborhood Hits	1644	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYO15_HUMAN
NC score	0.006908 (rank : 84)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	68	Target Neighborhood Hits	671	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CAC1B_MOUSE
NC score	0.004564 (rank : 85)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	68	Target Neighborhood Hits	351	Shared Neighborhood Hits	2
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

ACHB4_MOUSE
NC score	0.003893 (rank : 86)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	68	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R493, Q8VI06	Gene names	Chrnb4, Acrb4
Domain Architecture	No domain graphic available
Description	Neuronal acetylcholine receptor protein subunit beta-4 precursor.

MUC1_HUMAN
NC score	0.002900 (rank : 87)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	68	Target Neighborhood Hits	975	Shared Neighborhood Hits	6
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

STK10_HUMAN
NC score	0.002609 (rank : 88)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	68	Target Neighborhood Hits	1921	Shared Neighborhood Hits	8
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SALL1_HUMAN
NC score	0.001584 (rank : 89)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	68	Target Neighborhood Hits	821	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSC2, Q99881, Q9NSC3, Q9P1R0	Gene names	SALL1, SAL1
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein SALL1) (Spalt-like transcription factor 1) (HSal1).

TITIN_HUMAN
NC score	0.000148 (rank : 90)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	68	Target Neighborhood Hits	2923	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).