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Network neighborhood for query Sequence : OSTP_MOUSE

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OSTP_MOUSE
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OSTP_MOUSE
θ value	1.33454e-136 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

OSTP_HUMAN
θ value	7.19216e-82 (rank : 2)	NC score	0.937910 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	P10451, Q15681, Q15682, Q15683, Q8NBK2, Q96IZ1	Gene names	SPP1, OPN
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Nephropontin) (Uropontin).

LEO1_MOUSE
θ value	0.000786445 (rank : 3)	NC score	0.165527 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	946	Shared Neighborhood Hits	38
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

IWS1_HUMAN
θ value	0.00298849 (rank : 4)	NC score	0.153552 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	1241	Shared Neighborhood Hits	41
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DSPP_MOUSE
θ value	0.00665767 (rank : 5)	NC score	0.185491 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	491	Shared Neighborhood Hits	24
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_HUMAN
θ value	0.00869519 (rank : 6)	NC score	0.174733 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	645	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LEO1_HUMAN
θ value	0.00869519 (rank : 7)	NC score	0.172100 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	958	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

DMP1_HUMAN
θ value	0.0148317 (rank : 8)	NC score	0.194036 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	491	Shared Neighborhood Hits	30
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

SMRCD_HUMAN
θ value	0.0252991 (rank : 9)	NC score	0.040751 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

VPS72_HUMAN
θ value	0.0330416 (rank : 10)	NC score	0.161291 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	18
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
θ value	0.0330416 (rank : 11)	NC score	0.163512 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	286	Shared Neighborhood Hits	20
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

DMP1_MOUSE
θ value	0.21417 (rank : 12)	NC score	0.162082 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	498	Shared Neighborhood Hits	28
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

TGON2_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.094103 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	1037	Shared Neighborhood Hits	33
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

BRCA1_MOUSE
θ value	0.365318 (rank : 14)	NC score	0.062193 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	436	Shared Neighborhood Hits	17
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

ZBP1_MOUSE
θ value	0.47712 (rank : 15)	NC score	0.070331 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY24, Q8VE02, Q9D8B9	Gene names	Zbp1, Dlm1
Domain Architecture
Description	Z-DNA-binding protein 1 (Tumor stroma and activated macrophage protein DLM-1).

SPRL1_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.085495 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	403	Shared Neighborhood Hits	28
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CD2L1_MOUSE
θ value	1.06291 (rank : 17)	NC score	0.019857 (rank : 83)
Query Neighborhood Hits	60	Target Neighborhood Hits	1463	Shared Neighborhood Hits	36
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

KINH_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.016164 (rank : 87)
Query Neighborhood Hits	60	Target Neighborhood Hits	1231	Shared Neighborhood Hits	14
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

ABTAP_MOUSE
θ value	1.38821 (rank : 19)	NC score	0.080182 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	381	Shared Neighborhood Hits	21
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

PF21A_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.030549 (rank : 74)
Query Neighborhood Hits	60	Target Neighborhood Hits	303	Shared Neighborhood Hits	4
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PRP4B_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.026259 (rank : 79)
Query Neighborhood Hits	60	Target Neighborhood Hits	1040	Shared Neighborhood Hits	23
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

RBBP6_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.083938 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	1135	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

UBP26_MOUSE
θ value	1.38821 (rank : 23)	NC score	0.033466 (rank : 71)
Query Neighborhood Hits	60	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

CAC1G_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.016295 (rank : 86)
Query Neighborhood Hits	60	Target Neighborhood Hits	587	Shared Neighborhood Hits	2
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

IWS1_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.129865 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	1258	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYLK_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.006969 (rank : 93)
Query Neighborhood Hits	60	Target Neighborhood Hits	1328	Shared Neighborhood Hits	11
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

PRP4B_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.023302 (rank : 81)
Query Neighborhood Hits	60	Target Neighborhood Hits	1030	Shared Neighborhood Hits	26
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

STA13_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.030391 (rank : 75)
Query Neighborhood Hits	60	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

ANR11_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.034644 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	1289	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

PGFRA_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.010210 (rank : 90)
Query Neighborhood Hits	60	Target Neighborhood Hits	975	Shared Neighborhood Hits	7
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

RBBP6_MOUSE
θ value	2.36792 (rank : 31)	NC score	0.087869 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	1014	Shared Neighborhood Hits	32
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

THOC2_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.091921 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	337	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

AKA12_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.075513 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	825	Shared Neighborhood Hits	34
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

HELI_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.003245 (rank : 95)
Query Neighborhood Hits	60	Target Neighborhood Hits	723	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKS7, Q8N6S1	Gene names	IKZF2, HELIOS, ZNFN1A2
Domain Architecture	No domain graphic available
Description	Zinc finger protein Helios (IKAROS family zinc finger protein 2).

AFF4_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.056084 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	611	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ERCC5_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.043835 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

MYST3_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.043871 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	772	Shared Neighborhood Hits	31
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NCOA6_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.017456 (rank : 84)
Query Neighborhood Hits	60	Target Neighborhood Hits	1076	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

OSBL8_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.038517 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	289	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

STA13_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.032678 (rank : 72)
Query Neighborhood Hits	60	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

TXND2_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.098528 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	828	Shared Neighborhood Hits	34
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ANR12_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.026761 (rank : 78)
Query Neighborhood Hits	60	Target Neighborhood Hits	1081	Shared Neighborhood Hits	24
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

KINH_MOUSE
θ value	5.27518 (rank : 43)	NC score	0.013773 (rank : 89)
Query Neighborhood Hits	60	Target Neighborhood Hits	1082	Shared Neighborhood Hits	16
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

NMDE1_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.009791 (rank : 91)
Query Neighborhood Hits	60	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

TRPM3_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.015066 (rank : 88)
Query Neighborhood Hits	60	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

ZF106_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.031117 (rank : 73)
Query Neighborhood Hits	60	Target Neighborhood Hits	470	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

ALMS1_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.025311 (rank : 80)
Query Neighborhood Hits	60	Target Neighborhood Hits	356	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

BRD2_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.027367 (rank : 77)
Query Neighborhood Hits	60	Target Neighborhood Hits	242	Shared Neighborhood Hits	16
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

CCAR1_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.053642 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	444	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CLSPN_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.045343 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	292	Shared Neighborhood Hits	18
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

K0528_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.016915 (rank : 85)
Query Neighborhood Hits	60	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

PGFRA_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.008786 (rank : 92)
Query Neighborhood Hits	60	Target Neighborhood Hits	980	Shared Neighborhood Hits	7
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

RBM6_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.028398 (rank : 76)
Query Neighborhood Hits	60	Target Neighborhood Hits	221	Shared Neighborhood Hits	6
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

SEC63_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.037600 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	601	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

ZFP38_HUMAN
θ value	6.88961 (rank : 55)	NC score	-0.000109 (rank : 96)
Query Neighborhood Hits	60	Target Neighborhood Hits	766	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5A6, Q9H0B5	Gene names	ZNF38, ZFP38, ZSCAN21
Domain Architecture
Description	Zinc finger protein 38 homolog (Zfp-38) (Zinc finger and SCAN domain- containing protein 21) (NY-REN-21 antigen).

ASPH_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.047258 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

ICAL_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.037508 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	178	Shared Neighborhood Hits	12
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

LMNB1_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.005667 (rank : 94)
Query Neighborhood Hits	60	Target Neighborhood Hits	719	Shared Neighborhood Hits	9
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

NKTR_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.042990 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	658	Shared Neighborhood Hits	31
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NRIP1_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.022733 (rank : 82)
Query Neighborhood Hits	60	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

ABTAP_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.060754 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	290	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ATRX_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.060416 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	682	Shared Neighborhood Hits	33
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CTR9_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.056220 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	427	Shared Neighborhood Hits	20
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

CYLC1_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.070799 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	408	Shared Neighborhood Hits	20
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CYLC2_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.089096 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	223	Shared Neighborhood Hits	18
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

DAXX_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.051996 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

DAXX_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.051851 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	173	Shared Neighborhood Hits	18
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

ERIC1_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.056606 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	364	Shared Neighborhood Hits	21
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

FILA_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.059310 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	685	Shared Neighborhood Hits	22
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GPTC8_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.052806 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	366	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

HIRP3_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.063218 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	323	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

HTSF1_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.068867 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	408	Shared Neighborhood Hits	28
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

HTSF1_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.073197 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

LRRF1_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.050317 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	440	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

MDN1_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.058178 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	662	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NIPBL_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.066497 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	1311	Shared Neighborhood Hits	37
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.056066 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	1041	Shared Neighborhood Hits	34
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NSBP1_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.088002 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	251	Shared Neighborhood Hits	19
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NSBP1_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.068505 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	681	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NUCKS_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.098081 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	143	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

NUCKS_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.097132 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

PTMA_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.082229 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.089822 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.056725 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	111	Shared Neighborhood Hits	11
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.066878 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

RPTN_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.053864 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	650	Shared Neighborhood Hits	24
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SCG1_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.052157 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

SFR11_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.055862 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	246	Shared Neighborhood Hits	15
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SG16_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.060343 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	P02815, Q62263	Gene names	Spt1, Spt-1
Domain Architecture	No domain graphic available
Description	16.5 kDa submandibular gland glycoprotein precursor (Salivary protein 1).

SPRL1_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.056892 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SRCH_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.060317 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	16
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

T2FA_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.073637 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TGON1_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.051588 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	243	Shared Neighborhood Hits	14
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TGON2_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.052402 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	277	Shared Neighborhood Hits	14
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

UBF1_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.050248 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	415	Shared Neighborhood Hits	25
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

YTDC1_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.071037 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	458	Shared Neighborhood Hits	35
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

Hits sorted by NC score

OSTP_MOUSE
NC score	0.999962 (rank : 1)	θ value	1.33454e-136 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

OSTP_HUMAN
NC score	0.937910 (rank : 2)	θ value	7.19216e-82 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	P10451, Q15681, Q15682, Q15683, Q8NBK2, Q96IZ1	Gene names	SPP1, OPN
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Nephropontin) (Uropontin).

DMP1_HUMAN
NC score	0.194036 (rank : 3)	θ value	0.0148317 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	491	Shared Neighborhood Hits	30
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DSPP_MOUSE
NC score	0.185491 (rank : 4)	θ value	0.00665767 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	491	Shared Neighborhood Hits	24
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_HUMAN
NC score	0.174733 (rank : 5)	θ value	0.00869519 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	645	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LEO1_HUMAN
NC score	0.172100 (rank : 6)	θ value	0.00869519 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	958	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
NC score	0.165527 (rank : 7)	θ value	0.000786445 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	946	Shared Neighborhood Hits	38
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

VPS72_MOUSE
NC score	0.163512 (rank : 8)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	286	Shared Neighborhood Hits	20
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

DMP1_MOUSE
NC score	0.162082 (rank : 9)	θ value	0.21417 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	498	Shared Neighborhood Hits	28
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

VPS72_HUMAN
NC score	0.161291 (rank : 10)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	18
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

IWS1_HUMAN
NC score	0.153552 (rank : 11)	θ value	0.00298849 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	1241	Shared Neighborhood Hits	41
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
NC score	0.129865 (rank : 12)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	1258	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TXND2_MOUSE
NC score	0.098528 (rank : 13)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	828	Shared Neighborhood Hits	34
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

NUCKS_HUMAN
NC score	0.098081 (rank : 14)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	60	Target Neighborhood Hits	143	Shared Neighborhood Hits	18
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

NUCKS_MOUSE
NC score	0.097132 (rank : 15)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	60	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	Q80XU3, Q8BVD8	Gene names	Nucks1, Nucks
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (JC7).

TGON2_HUMAN
NC score	0.094103 (rank : 16)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	1037	Shared Neighborhood Hits	33
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

THOC2_HUMAN
NC score	0.091921 (rank : 17)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	337	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

PTMA_MOUSE
NC score	0.089822 (rank : 18)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	60	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

CYLC2_HUMAN
NC score	0.089096 (rank : 19)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	223	Shared Neighborhood Hits	18
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

NSBP1_HUMAN
NC score	0.088002 (rank : 20)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	60	Target Neighborhood Hits	251	Shared Neighborhood Hits	19
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

RBBP6_MOUSE
NC score	0.087869 (rank : 21)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	1014	Shared Neighborhood Hits	32
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SPRL1_MOUSE
NC score	0.085495 (rank : 22)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	403	Shared Neighborhood Hits	28
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

RBBP6_HUMAN
NC score	0.083938 (rank : 23)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	1135	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

PTMA_HUMAN
NC score	0.082229 (rank : 24)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	60	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

ABTAP_MOUSE
NC score	0.080182 (rank : 25)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	381	Shared Neighborhood Hits	21
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

AKA12_HUMAN
NC score	0.075513 (rank : 26)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	825	Shared Neighborhood Hits	34
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

T2FA_HUMAN
NC score	0.073637 (rank : 27)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	60	Target Neighborhood Hits	228	Shared Neighborhood Hits	20
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

HTSF1_MOUSE
NC score	0.073197 (rank : 28)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	60	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

YTDC1_HUMAN
NC score	0.071037 (rank : 29)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	60	Target Neighborhood Hits	458	Shared Neighborhood Hits	35
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

CYLC1_HUMAN
NC score	0.070799 (rank : 30)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	408	Shared Neighborhood Hits	20
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

ZBP1_MOUSE
NC score	0.070331 (rank : 31)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QY24, Q8VE02, Q9D8B9	Gene names	Zbp1, Dlm1
Domain Architecture
Description	Z-DNA-binding protein 1 (Tumor stroma and activated macrophage protein DLM-1).

HTSF1_HUMAN
NC score	0.068867 (rank : 32)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	60	Target Neighborhood Hits	408	Shared Neighborhood Hits	28
SwissProt Accessions	O43719, Q59G06, Q99730	Gene names	HTATSF1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 (Tat-SF1).

NSBP1_MOUSE
NC score	0.068505 (rank : 33)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	60	Target Neighborhood Hits	681	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

PTMS_MOUSE
NC score	0.066878 (rank : 34)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	60	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

NIPBL_HUMAN
NC score	0.066497 (rank : 35)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	60	Target Neighborhood Hits	1311	Shared Neighborhood Hits	37
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

HIRP3_HUMAN
NC score	0.063218 (rank : 36)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	60	Target Neighborhood Hits	323	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

BRCA1_MOUSE
NC score	0.062193 (rank : 37)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	436	Shared Neighborhood Hits	17
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

ABTAP_HUMAN
NC score	0.060754 (rank : 38)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	290	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H501, Q86X92, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6	Gene names	ABTAP, C20orf6
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

ATRX_MOUSE
NC score	0.060416 (rank : 39)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	682	Shared Neighborhood Hits	33
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SG16_MOUSE
NC score	0.060343 (rank : 40)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	8
SwissProt Accessions	P02815, Q62263	Gene names	Spt1, Spt-1
Domain Architecture	No domain graphic available
Description	16.5 kDa submandibular gland glycoprotein precursor (Salivary protein 1).

SRCH_HUMAN
NC score	0.060317 (rank : 41)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	16
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

FILA_HUMAN
NC score	0.059310 (rank : 42)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	685	Shared Neighborhood Hits	22
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

MDN1_HUMAN
NC score	0.058178 (rank : 43)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	60	Target Neighborhood Hits	662	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

SPRL1_HUMAN
NC score	0.056892 (rank : 44)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	60	Target Neighborhood Hits	231	Shared Neighborhood Hits	19
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

PTMS_HUMAN
NC score	0.056725 (rank : 45)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	60	Target Neighborhood Hits	111	Shared Neighborhood Hits	11
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

ERIC1_HUMAN
NC score	0.056606 (rank : 46)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	364	Shared Neighborhood Hits	21
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

CTR9_MOUSE
NC score	0.056220 (rank : 47)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	427	Shared Neighborhood Hits	20
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

AFF4_HUMAN
NC score	0.056084 (rank : 48)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	611	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

NPBL_MOUSE
NC score	0.056066 (rank : 49)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	60	Target Neighborhood Hits	1041	Shared Neighborhood Hits	34
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SFR11_HUMAN
NC score	0.055862 (rank : 50)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	60	Target Neighborhood Hits	246	Shared Neighborhood Hits	15
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

RPTN_MOUSE
NC score	0.053864 (rank : 51)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	60	Target Neighborhood Hits	650	Shared Neighborhood Hits	24
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

CCAR1_HUMAN
NC score	0.053642 (rank : 52)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	444	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

GPTC8_HUMAN
NC score	0.052806 (rank : 53)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	366	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

TGON2_MOUSE
NC score	0.052402 (rank : 54)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	60	Target Neighborhood Hits	277	Shared Neighborhood Hits	14
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

SCG1_HUMAN
NC score	0.052157 (rank : 55)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	60	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	P05060, Q9BQV6, Q9UJA6	Gene names	CHGB, SCG1
Domain Architecture
Description	Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide].

DAXX_HUMAN
NC score	0.051996 (rank : 56)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UER7, O14747, O15141, O15208, Q9BWI3	Gene names	DAXX, BING2, DAP6
Domain Architecture
Description	Death domain-associated protein 6 (Daxx) (hDaxx) (Fas death domain- associated protein) (ETS1-associated protein 1) (EAP1).

DAXX_MOUSE
NC score	0.051851 (rank : 57)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	173	Shared Neighborhood Hits	18
SwissProt Accessions	O35613, Q9QWT8, Q9QWV3	Gene names	Daxx
Domain Architecture
Description	Death domain-associated protein 6 (Daxx).

TGON1_MOUSE
NC score	0.051588 (rank : 58)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	60	Target Neighborhood Hits	243	Shared Neighborhood Hits	14
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

LRRF1_MOUSE
NC score	0.050317 (rank : 59)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	60	Target Neighborhood Hits	440	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

UBF1_HUMAN
NC score	0.050248 (rank : 60)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	60	Target Neighborhood Hits	415	Shared Neighborhood Hits	25
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

ASPH_HUMAN
NC score	0.047258 (rank : 61)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

CLSPN_MOUSE
NC score	0.045343 (rank : 62)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	292	Shared Neighborhood Hits	18
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

MYST3_HUMAN
NC score	0.043871 (rank : 63)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	772	Shared Neighborhood Hits	31
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

ERCC5_MOUSE
NC score	0.043835 (rank : 64)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	206	Shared Neighborhood Hits	10
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

NKTR_HUMAN
NC score	0.042990 (rank : 65)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	658	Shared Neighborhood Hits	31
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

SMRCD_HUMAN
NC score	0.040751 (rank : 66)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

OSBL8_HUMAN
NC score	0.038517 (rank : 67)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	289	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

SEC63_MOUSE
NC score	0.037600 (rank : 68)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	601	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

ICAL_MOUSE
NC score	0.037508 (rank : 69)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	178	Shared Neighborhood Hits	12
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

ANR11_HUMAN
NC score	0.034644 (rank : 70)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	1289	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

UBP26_MOUSE
NC score	0.033466 (rank : 71)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

STA13_MOUSE
NC score	0.032678 (rank : 72)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

ZF106_HUMAN
NC score	0.031117 (rank : 73)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	470	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

PF21A_HUMAN
NC score	0.030549 (rank : 74)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	303	Shared Neighborhood Hits	4
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

STA13_HUMAN
NC score	0.030391 (rank : 75)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

RBM6_HUMAN
NC score	0.028398 (rank : 76)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	221	Shared Neighborhood Hits	6
SwissProt Accessions	P78332, O60549, O75524	Gene names	RBM6, DEF3
Domain Architecture
Description	RNA-binding protein 6 (RNA-binding motif protein 6) (RNA-binding protein DEF-3) (Lung cancer antigen NY-LU-12) (Protein G16).

BRD2_HUMAN
NC score	0.027367 (rank : 77)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	242	Shared Neighborhood Hits	16
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

ANR12_HUMAN
NC score	0.026761 (rank : 78)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	1081	Shared Neighborhood Hits	24
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

PRP4B_MOUSE
NC score	0.026259 (rank : 79)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	1040	Shared Neighborhood Hits	23
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

ALMS1_HUMAN
NC score	0.025311 (rank : 80)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	356	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

PRP4B_HUMAN
NC score	0.023302 (rank : 81)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	1030	Shared Neighborhood Hits	26
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

NRIP1_MOUSE
NC score	0.022733 (rank : 82)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

CD2L1_MOUSE
NC score	0.019857 (rank : 83)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	1463	Shared Neighborhood Hits	36
SwissProt Accessions	P24788, Q3UI03, Q61399, Q7TST4, Q8BP53	Gene names	Cdc2l1
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L1 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 1).

NCOA6_MOUSE
NC score	0.017456 (rank : 84)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	1076	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

K0528_HUMAN
NC score	0.016915 (rank : 85)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

CAC1G_HUMAN
NC score	0.016295 (rank : 86)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	587	Shared Neighborhood Hits	2
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

KINH_HUMAN
NC score	0.016164 (rank : 87)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	1231	Shared Neighborhood Hits	14
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

TRPM3_HUMAN
NC score	0.015066 (rank : 88)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

KINH_MOUSE
NC score	0.013773 (rank : 89)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	1082	Shared Neighborhood Hits	16
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

PGFRA_MOUSE
NC score	0.010210 (rank : 90)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	975	Shared Neighborhood Hits	7
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

NMDE1_MOUSE
NC score	0.009791 (rank : 91)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	P35436	Gene names	Grin2a
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit epsilon 1 precursor (N-methyl D- aspartate receptor subtype 2A) (NR2A) (NMDAR2A).

PGFRA_HUMAN
NC score	0.008786 (rank : 92)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	980	Shared Neighborhood Hits	7
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

MYLK_HUMAN
NC score	0.006969 (rank : 93)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	1328	Shared Neighborhood Hits	11
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

LMNB1_MOUSE
NC score	0.005667 (rank : 94)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	719	Shared Neighborhood Hits	9
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

HELI_HUMAN
NC score	0.003245 (rank : 95)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	723	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKS7, Q8N6S1	Gene names	IKZF2, HELIOS, ZNFN1A2
Domain Architecture	No domain graphic available
Description	Zinc finger protein Helios (IKAROS family zinc finger protein 2).

ZFP38_HUMAN
NC score	-0.000109 (rank : 96)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	766	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5A6, Q9H0B5	Gene names	ZNF38, ZFP38, ZSCAN21
Domain Architecture
Description	Zinc finger protein 38 homolog (Zfp-38) (Zinc finger and SCAN domain- containing protein 21) (NY-REN-21 antigen).