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Network neighborhood for query Sequence : NRIP1_MOUSE

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NRIP1_MOUSE
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NRIP1_HUMAN
θ value	0 (rank : 1)	NC score	0.963568 (rank : 2)
Query Neighborhood Hits	110	Target Neighborhood Hits	88	Shared Neighborhood Hits	21
SwissProt Accessions	P48552, Q8IWE8	Gene names	NRIP1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

NRIP1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	110	Target Neighborhood Hits	110	Shared Neighborhood Hits	110
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

SRBS1_MOUSE
θ value	0.00390308 (rank : 3)	NC score	0.057960 (rank : 8)
Query Neighborhood Hits	110	Target Neighborhood Hits	409	Shared Neighborhood Hits	9
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SYNPO_HUMAN
θ value	0.00665767 (rank : 4)	NC score	0.081441 (rank : 4)
Query Neighborhood Hits	110	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

DSPP_HUMAN
θ value	0.0193708 (rank : 5)	NC score	0.098988 (rank : 3)
Query Neighborhood Hits	110	Target Neighborhood Hits	645	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MLL2_HUMAN
θ value	0.0431538 (rank : 6)	NC score	0.043241 (rank : 24)
Query Neighborhood Hits	110	Target Neighborhood Hits	1788	Shared Neighborhood Hits	45
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

AF9_HUMAN
θ value	0.0736092 (rank : 7)	NC score	0.072095 (rank : 5)
Query Neighborhood Hits	110	Target Neighborhood Hits	202	Shared Neighborhood Hits	14
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

LR37A_HUMAN
θ value	0.0736092 (rank : 8)	NC score	0.061070 (rank : 6)
Query Neighborhood Hits	110	Target Neighborhood Hits	720	Shared Neighborhood Hits	26
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

LR37B_HUMAN
θ value	0.0736092 (rank : 9)	NC score	0.055545 (rank : 13)
Query Neighborhood Hits	110	Target Neighborhood Hits	392	Shared Neighborhood Hits	9
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

T3JAM_HUMAN
θ value	0.0736092 (rank : 10)	NC score	0.060758 (rank : 7)
Query Neighborhood Hits	110	Target Neighborhood Hits	533	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

K0460_HUMAN
θ value	0.125558 (rank : 11)	NC score	0.056172 (rank : 12)
Query Neighborhood Hits	110	Target Neighborhood Hits	357	Shared Neighborhood Hits	15
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

MPIP1_MOUSE
θ value	0.125558 (rank : 12)	NC score	0.047114 (rank : 18)
Query Neighborhood Hits	110	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P48964	Gene names	Cdc25a, Cdc25m3
Domain Architecture
Description	M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A).

FA8_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.033699 (rank : 37)
Query Neighborhood Hits	110	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

REPS2_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.045313 (rank : 21)
Query Neighborhood Hits	110	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

MARCS_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.056629 (rank : 11)
Query Neighborhood Hits	110	Target Neighborhood Hits	204	Shared Neighborhood Hits	9
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

PRG4_MOUSE
θ value	0.21417 (rank : 16)	NC score	0.038400 (rank : 27)
Query Neighborhood Hits	110	Target Neighborhood Hits	624	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

WDR22_MOUSE
θ value	0.21417 (rank : 17)	NC score	0.047664 (rank : 17)
Query Neighborhood Hits	110	Target Neighborhood Hits	302	Shared Neighborhood Hits	6
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

APC_HUMAN
θ value	0.279714 (rank : 18)	NC score	0.057525 (rank : 9)
Query Neighborhood Hits	110	Target Neighborhood Hits	603	Shared Neighborhood Hits	24
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

SRRM2_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.052969 (rank : 15)
Query Neighborhood Hits	110	Target Neighborhood Hits	1296	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CO4A4_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.039696 (rank : 25)
Query Neighborhood Hits	110	Target Neighborhood Hits	440	Shared Neighborhood Hits	16
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

WDR22_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.045605 (rank : 20)
Query Neighborhood Hits	110	Target Neighborhood Hits	328	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

ANLN_MOUSE
θ value	0.47712 (rank : 22)	NC score	0.043280 (rank : 23)
Query Neighborhood Hits	110	Target Neighborhood Hits	297	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CHD1_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.028796 (rank : 52)
Query Neighborhood Hits	110	Target Neighborhood Hits	337	Shared Neighborhood Hits	12
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

FOXP1_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.023162 (rank : 64)
Query Neighborhood Hits	110	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H334, Q9H332, Q9H333, Q9P0R1	Gene names	FOXP1
Domain Architecture
Description	Forkhead box protein P1.

CHD1_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.027349 (rank : 58)
Query Neighborhood Hits	110	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CO4A1_MOUSE
θ value	1.06291 (rank : 26)	NC score	0.036564 (rank : 30)
Query Neighborhood Hits	110	Target Neighborhood Hits	450	Shared Neighborhood Hits	19
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

KAISO_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.007792 (rank : 95)
Query Neighborhood Hits	110	Target Neighborhood Hits	840	Shared Neighborhood Hits	8
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

BAZ2B_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.034666 (rank : 33)
Query Neighborhood Hits	110	Target Neighborhood Hits	803	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

DSPP_MOUSE
θ value	1.38821 (rank : 29)	NC score	0.057315 (rank : 10)
Query Neighborhood Hits	110	Target Neighborhood Hits	491	Shared Neighborhood Hits	24
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GOGA2_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.027634 (rank : 57)
Query Neighborhood Hits	110	Target Neighborhood Hits	856	Shared Neighborhood Hits	14
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

K0240_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.053503 (rank : 14)
Query Neighborhood Hits	110	Target Neighborhood Hits	211	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

SRRM2_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.045055 (rank : 22)
Query Neighborhood Hits	110	Target Neighborhood Hits	1470	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

AP3B1_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.022307 (rank : 69)
Query Neighborhood Hits	110	Target Neighborhood Hits	283	Shared Neighborhood Hits	12
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

APC_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.049266 (rank : 16)
Query Neighborhood Hits	110	Target Neighborhood Hits	441	Shared Neighborhood Hits	14
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

CO7A1_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.024825 (rank : 60)
Query Neighborhood Hits	110	Target Neighborhood Hits	807	Shared Neighborhood Hits	17
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

FOXP1_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.020943 (rank : 71)
Query Neighborhood Hits	110	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	P58462	Gene names	Foxp1
Domain Architecture
Description	Forkhead box protein P1 (Forkhead-related transcription factor 1).

K0240_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.046141 (rank : 19)
Query Neighborhood Hits	110	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q6AI39, Q5TFZ3, Q92514	Gene names	KIAA0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

C1QC_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.028849 (rank : 51)
Query Neighborhood Hits	110	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

CO4A1_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.033654 (rank : 38)
Query Neighborhood Hits	110	Target Neighborhood Hits	425	Shared Neighborhood Hits	17
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

DGCR8_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.035850 (rank : 32)
Query Neighborhood Hits	110	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

IF4B_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.030730 (rank : 45)
Query Neighborhood Hits	110	Target Neighborhood Hits	417	Shared Neighborhood Hits	18
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MUC5B_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.020275 (rank : 74)
Query Neighborhood Hits	110	Target Neighborhood Hits	1020	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PO121_MOUSE
θ value	2.36792 (rank : 43)	NC score	0.027670 (rank : 56)
Query Neighborhood Hits	110	Target Neighborhood Hits	345	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

RCOR2_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.038182 (rank : 28)
Query Neighborhood Hits	110	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

RCOR2_MOUSE
θ value	2.36792 (rank : 45)	NC score	0.038121 (rank : 29)
Query Neighborhood Hits	110	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

SCN5A_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.009876 (rank : 91)
Query Neighborhood Hits	110	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

TARA_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.030647 (rank : 47)
Query Neighborhood Hits	110	Target Neighborhood Hits	1133	Shared Neighborhood Hits	36
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ECHB_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.023229 (rank : 63)
Query Neighborhood Hits	110	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JY0, Q3TEH9, Q8BJI5, Q8BJM0, Q8BK52	Gene names	Hadhb
Domain Architecture	No domain graphic available
Description	Trifunctional enzyme subunit beta, mitochondrial precursor (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)].

HUWE1_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.014407 (rank : 84)
Query Neighborhood Hits	110	Target Neighborhood Hits	406	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

NCOR1_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.034404 (rank : 35)
Query Neighborhood Hits	110	Target Neighborhood Hits	577	Shared Neighborhood Hits	25
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

RIF1_MOUSE
θ value	3.0926 (rank : 51)	NC score	0.032303 (rank : 41)
Query Neighborhood Hits	110	Target Neighborhood Hits	315	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

SRPK1_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.012783 (rank : 86)
Query Neighborhood Hits	110	Target Neighborhood Hits	706	Shared Neighborhood Hits	15
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

TNIK_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.004074 (rank : 102)
Query Neighborhood Hits	110	Target Neighborhood Hits	1570	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

UBP32_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.018471 (rank : 76)
Query Neighborhood Hits	110	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

CADH1_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.004218 (rank : 101)
Query Neighborhood Hits	110	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	P09803, Q61377	Gene names	Cdh1
Domain Architecture
Description	Epithelial-cadherin precursor (E-cadherin) (Uvomorulin) (Cadherin-1) (ARC-1) (CD324 antigen) [Contains: E-Cad/CTF1; E-Cad/CTF2; E- Cad/CTF3].

CO4A2_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.031016 (rank : 44)
Query Neighborhood Hits	110	Target Neighborhood Hits	454	Shared Neighborhood Hits	18
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

KCNA6_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.006948 (rank : 97)
Query Neighborhood Hits	110	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

M3K2_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.002846 (rank : 105)
Query Neighborhood Hits	110	Target Neighborhood Hits	846	Shared Neighborhood Hits	8
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

PRDM9_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.002018 (rank : 108)
Query Neighborhood Hits	110	Target Neighborhood Hits	750	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQV7	Gene names	PRDM9, PFM6
Domain Architecture
Description	PR domain zinc finger protein 9 (PR domain-containing protein 9).

TGFR2_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.005784 (rank : 98)
Query Neighborhood Hits	110	Target Neighborhood Hits	748	Shared Neighborhood Hits	7
SwissProt Accessions	Q62312, Q63947	Gene names	Tgfbr2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

UBE4B_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.022311 (rank : 68)
Query Neighborhood Hits	110	Target Neighborhood Hits	158	Shared Neighborhood Hits	8
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

CO4A3_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.031750 (rank : 43)
Query Neighborhood Hits	110	Target Neighborhood Hits	421	Shared Neighborhood Hits	16
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO4A5_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.038900 (rank : 26)
Query Neighborhood Hits	110	Target Neighborhood Hits	383	Shared Neighborhood Hits	19
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

DACH1_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.017739 (rank : 79)
Query Neighborhood Hits	110	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

ECHB_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.020864 (rank : 72)
Query Neighborhood Hits	110	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P55084, O14969, Q53TA6, Q96C77, Q9H3F5	Gene names	HADHB
Domain Architecture
Description	Trifunctional enzyme subunit beta, mitochondrial precursor (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)].

LIMA1_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.015468 (rank : 81)
Query Neighborhood Hits	110	Target Neighborhood Hits	309	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

NCOR2_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.026823 (rank : 59)
Query Neighborhood Hits	110	Target Neighborhood Hits	790	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PHF2_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.013029 (rank : 85)
Query Neighborhood Hits	110	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

UBF1_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.015356 (rank : 83)
Query Neighborhood Hits	110	Target Neighborhood Hits	415	Shared Neighborhood Hits	10
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

VATC_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.030652 (rank : 46)
Query Neighborhood Hits	110	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P21283	Gene names	ATP6V1C1, ATP6C, ATP6D, VATC
Domain Architecture
Description	Vacuolar ATP synthase subunit C (EC 3.6.3.14) (V-ATPase C subunit) (Vacuolar proton pump C subunit).

VATC_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.030591 (rank : 48)
Query Neighborhood Hits	110	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1G3	Gene names	Atp6v1c1, Atp6c, Vatc
Domain Architecture
Description	Vacuolar ATP synthase subunit C (EC 3.6.3.14) (V-ATPase C subunit) (Vacuolar proton pump C subunit).

WNK4_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.004071 (rank : 103)
Query Neighborhood Hits	110	Target Neighborhood Hits	1043	Shared Neighborhood Hits	16
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZCH14_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.022430 (rank : 67)
Query Neighborhood Hits	110	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

CO4A6_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.030433 (rank : 49)
Query Neighborhood Hits	110	Target Neighborhood Hits	318	Shared Neighborhood Hits	15
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

COAA1_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.028621 (rank : 53)
Query Neighborhood Hits	110	Target Neighborhood Hits	316	Shared Neighborhood Hits	19
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

FYCO1_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.009853 (rank : 92)
Query Neighborhood Hits	110	Target Neighborhood Hits	1059	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

GIT2_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.007531 (rank : 96)
Query Neighborhood Hits	110	Target Neighborhood Hits	323	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

MACF1_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.011418 (rank : 89)
Query Neighborhood Hits	110	Target Neighborhood Hits	1341	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.015363 (rank : 82)
Query Neighborhood Hits	110	Target Neighborhood Hits	1321	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACOI_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.011399 (rank : 90)
Query Neighborhood Hits	110	Target Neighborhood Hits	650	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MAP1B_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.024159 (rank : 62)
Query Neighborhood Hits	110	Target Neighborhood Hits	977	Shared Neighborhood Hits	29
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MK10_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.002674 (rank : 106)
Query Neighborhood Hits	110	Target Neighborhood Hits	836	Shared Neighborhood Hits	8
SwissProt Accessions	P53779, Q15707	Gene names	MAPK10, JNK3, JNK3A, PRKM10
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

NCOA2_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.020486 (rank : 73)
Query Neighborhood Hits	110	Target Neighborhood Hits	281	Shared Neighborhood Hits	21
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NIPBL_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.032366 (rank : 39)
Query Neighborhood Hits	110	Target Neighborhood Hits	1311	Shared Neighborhood Hits	36
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NOL8_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.036041 (rank : 31)
Query Neighborhood Hits	110	Target Neighborhood Hits	210	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

NPBL_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.034266 (rank : 36)
Query Neighborhood Hits	110	Target Neighborhood Hits	1041	Shared Neighborhood Hits	35
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NU214_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.028914 (rank : 50)
Query Neighborhood Hits	110	Target Neighborhood Hits	657	Shared Neighborhood Hits	22
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PEX19_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.019697 (rank : 75)
Query Neighborhood Hits	110	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCI5, Q8CEE1, Q921H0, Q9CZC1, Q9QUQ1	Gene names	Pex19, Pxf
Domain Architecture	No domain graphic available
Description	Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein) (PxF).

PODXL_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.031883 (rank : 42)
Query Neighborhood Hits	110	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

RXRG_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.003888 (rank : 104)
Query Neighborhood Hits	110	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

S6OS1_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.016728 (rank : 80)
Query Neighborhood Hits	110	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CTN5, Q9D5F5, Q9D5Y9	Gene names	Six6os1
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

SCEL_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.034574 (rank : 34)
Query Neighborhood Hits	110	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQG3, Q9CTT9	Gene names	Scel
Domain Architecture
Description	Sciellin.

SFR17_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.024562 (rank : 61)
Query Neighborhood Hits	110	Target Neighborhood Hits	325	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

AKAP6_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.032344 (rank : 40)
Query Neighborhood Hits	110	Target Neighborhood Hits	263	Shared Neighborhood Hits	17
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

AP4E1_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.009733 (rank : 93)
Query Neighborhood Hits	110	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

ARHGC_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.005717 (rank : 99)
Query Neighborhood Hits	110	Target Neighborhood Hits	351	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CO5A1_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.027971 (rank : 55)
Query Neighborhood Hits	110	Target Neighborhood Hits	434	Shared Neighborhood Hits	19
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CO5A1_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.027985 (rank : 54)
Query Neighborhood Hits	110	Target Neighborhood Hits	419	Shared Neighborhood Hits	18
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

DJBP_MOUSE
θ value	8.99809 (rank : 99)	NC score	0.011936 (rank : 87)
Query Neighborhood Hits	110	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

MAGC1_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.011481 (rank : 88)
Query Neighborhood Hits	110	Target Neighborhood Hits	431	Shared Neighborhood Hits	12
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MINT_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.018228 (rank : 77)
Query Neighborhood Hits	110	Target Neighborhood Hits	1514	Shared Neighborhood Hits	43
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MK10_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.002562 (rank : 107)
Query Neighborhood Hits	110	Target Neighborhood Hits	849	Shared Neighborhood Hits	10
SwissProt Accessions	Q61831, Q9R0U6	Gene names	Mapk10, Jnk3, Prkm10, Serk2
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

MTF1_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.000551 (rank : 110)
Query Neighborhood Hits	110	Target Neighborhood Hits	814	Shared Neighborhood Hits	9
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

NCOA2_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.017984 (rank : 78)
Query Neighborhood Hits	110	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NFH_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.023027 (rank : 65)
Query Neighborhood Hits	110	Target Neighborhood Hits	2247	Shared Neighborhood Hits	58
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OSTP_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.022733 (rank : 66)
Query Neighborhood Hits	110	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

PLCB1_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.005654 (rank : 100)
Query Neighborhood Hits	110	Target Neighborhood Hits	531	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

SDC3_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.021567 (rank : 70)
Query Neighborhood Hits	110	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SP2_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.000878 (rank : 109)
Query Neighborhood Hits	110	Target Neighborhood Hits	747	Shared Neighborhood Hits	6
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.

SYN1_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.009600 (rank : 94)
Query Neighborhood Hits	110	Target Neighborhood Hits	363	Shared Neighborhood Hits	12
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

Hits sorted by NC score

NRIP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	110	Target Neighborhood Hits	110	Shared Neighborhood Hits	110
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

NRIP1_HUMAN
NC score	0.963568 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	110	Target Neighborhood Hits	88	Shared Neighborhood Hits	21
SwissProt Accessions	P48552, Q8IWE8	Gene names	NRIP1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

DSPP_HUMAN
NC score	0.098988 (rank : 3)	θ value	0.0193708 (rank : 5)
Query Neighborhood Hits	110	Target Neighborhood Hits	645	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SYNPO_HUMAN
NC score	0.081441 (rank : 4)	θ value	0.00665767 (rank : 4)
Query Neighborhood Hits	110	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

AF9_HUMAN
NC score	0.072095 (rank : 5)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	110	Target Neighborhood Hits	202	Shared Neighborhood Hits	14
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

LR37A_HUMAN
NC score	0.061070 (rank : 6)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	110	Target Neighborhood Hits	720	Shared Neighborhood Hits	26
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

T3JAM_HUMAN
NC score	0.060758 (rank : 7)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	110	Target Neighborhood Hits	533	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

SRBS1_MOUSE
NC score	0.057960 (rank : 8)	θ value	0.00390308 (rank : 3)
Query Neighborhood Hits	110	Target Neighborhood Hits	409	Shared Neighborhood Hits	9
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

APC_HUMAN
NC score	0.057525 (rank : 9)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	110	Target Neighborhood Hits	603	Shared Neighborhood Hits	24
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

DSPP_MOUSE
NC score	0.057315 (rank : 10)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	110	Target Neighborhood Hits	491	Shared Neighborhood Hits	24
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MARCS_HUMAN
NC score	0.056629 (rank : 11)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	110	Target Neighborhood Hits	204	Shared Neighborhood Hits	9
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

K0460_HUMAN
NC score	0.056172 (rank : 12)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	110	Target Neighborhood Hits	357	Shared Neighborhood Hits	15
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

LR37B_HUMAN
NC score	0.055545 (rank : 13)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	110	Target Neighborhood Hits	392	Shared Neighborhood Hits	9
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

K0240_MOUSE
NC score	0.053503 (rank : 14)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	110	Target Neighborhood Hits	211	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

SRRM2_HUMAN
NC score	0.052969 (rank : 15)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	110	Target Neighborhood Hits	1296	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

APC_MOUSE
NC score	0.049266 (rank : 16)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	110	Target Neighborhood Hits	441	Shared Neighborhood Hits	14
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

WDR22_MOUSE
NC score	0.047664 (rank : 17)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	110	Target Neighborhood Hits	302	Shared Neighborhood Hits	6
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

MPIP1_MOUSE
NC score	0.047114 (rank : 18)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	110	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P48964	Gene names	Cdc25a, Cdc25m3
Domain Architecture
Description	M-phase inducer phosphatase 1 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25A).

K0240_HUMAN
NC score	0.046141 (rank : 19)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	110	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q6AI39, Q5TFZ3, Q92514	Gene names	KIAA0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

WDR22_HUMAN
NC score	0.045605 (rank : 20)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	110	Target Neighborhood Hits	328	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

REPS2_HUMAN
NC score	0.045313 (rank : 21)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	110	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFH8, O43428, Q8NFI5	Gene names	REPS2, POB1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

SRRM2_MOUSE
NC score	0.045055 (rank : 22)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	110	Target Neighborhood Hits	1470	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ANLN_MOUSE
NC score	0.043280 (rank : 23)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	110	Target Neighborhood Hits	297	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

MLL2_HUMAN
NC score	0.043241 (rank : 24)	θ value	0.0431538 (rank : 6)
Query Neighborhood Hits	110	Target Neighborhood Hits	1788	Shared Neighborhood Hits	45
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CO4A4_HUMAN
NC score	0.039696 (rank : 25)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	110	Target Neighborhood Hits	440	Shared Neighborhood Hits	16
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

CO4A5_HUMAN
NC score	0.038900 (rank : 26)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	110	Target Neighborhood Hits	383	Shared Neighborhood Hits	19
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

PRG4_MOUSE
NC score	0.038400 (rank : 27)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	110	Target Neighborhood Hits	624	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RCOR2_HUMAN
NC score	0.038182 (rank : 28)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	110	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

RCOR2_MOUSE
NC score	0.038121 (rank : 29)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	110	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

CO4A1_MOUSE
NC score	0.036564 (rank : 30)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	110	Target Neighborhood Hits	450	Shared Neighborhood Hits	19
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

NOL8_MOUSE
NC score	0.036041 (rank : 31)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	110	Target Neighborhood Hits	210	Shared Neighborhood Hits	5
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

DGCR8_HUMAN
NC score	0.035850 (rank : 32)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	110	Target Neighborhood Hits	72	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WYQ5, Q6DCB2, Q6MZE9, Q6Y2L0, Q96G39, Q96GP8, Q9H6L8, Q9H6T7, Q9NRW2	Gene names	DGCR8, C22orf12, DGCRK6
Domain Architecture
Description	DGCR8 protein (DiGeorge syndrome critical region 8).

BAZ2B_HUMAN
NC score	0.034666 (rank : 33)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	110	Target Neighborhood Hits	803	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

SCEL_MOUSE
NC score	0.034574 (rank : 34)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	110	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQG3, Q9CTT9	Gene names	Scel
Domain Architecture
Description	Sciellin.

NCOR1_HUMAN
NC score	0.034404 (rank : 35)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	110	Target Neighborhood Hits	577	Shared Neighborhood Hits	25
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NPBL_MOUSE
NC score	0.034266 (rank : 36)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	110	Target Neighborhood Hits	1041	Shared Neighborhood Hits	35
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

FA8_MOUSE
NC score	0.033699 (rank : 37)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	110	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

CO4A1_HUMAN
NC score	0.033654 (rank : 38)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	110	Target Neighborhood Hits	425	Shared Neighborhood Hits	17
SwissProt Accessions	P02462	Gene names	COL4A1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

NIPBL_HUMAN
NC score	0.032366 (rank : 39)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	110	Target Neighborhood Hits	1311	Shared Neighborhood Hits	36
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

AKAP6_HUMAN
NC score	0.032344 (rank : 40)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	110	Target Neighborhood Hits	263	Shared Neighborhood Hits	17
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

RIF1_MOUSE
NC score	0.032303 (rank : 41)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	110	Target Neighborhood Hits	315	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

PODXL_HUMAN
NC score	0.031883 (rank : 42)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	110	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

CO4A3_HUMAN
NC score	0.031750 (rank : 43)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	110	Target Neighborhood Hits	421	Shared Neighborhood Hits	16
SwissProt Accessions	Q01955, Q9BQT2	Gene names	COL4A3
Domain Architecture
Description	Collagen alpha-3(IV) chain precursor (Goodpasture antigen).

CO4A2_HUMAN
NC score	0.031016 (rank : 44)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	110	Target Neighborhood Hits	454	Shared Neighborhood Hits	18
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

IF4B_HUMAN
NC score	0.030730 (rank : 45)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	110	Target Neighborhood Hits	417	Shared Neighborhood Hits	18
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

VATC_HUMAN
NC score	0.030652 (rank : 46)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	110	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P21283	Gene names	ATP6V1C1, ATP6C, ATP6D, VATC
Domain Architecture
Description	Vacuolar ATP synthase subunit C (EC 3.6.3.14) (V-ATPase C subunit) (Vacuolar proton pump C subunit).

TARA_MOUSE
NC score	0.030647 (rank : 47)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	110	Target Neighborhood Hits	1133	Shared Neighborhood Hits	36
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

VATC_MOUSE
NC score	0.030591 (rank : 48)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	110	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1G3	Gene names	Atp6v1c1, Atp6c, Vatc
Domain Architecture
Description	Vacuolar ATP synthase subunit C (EC 3.6.3.14) (V-ATPase C subunit) (Vacuolar proton pump C subunit).

CO4A6_HUMAN
NC score	0.030433 (rank : 49)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	110	Target Neighborhood Hits	318	Shared Neighborhood Hits	15
SwissProt Accessions	Q14031, Q12823, Q14053, Q5JYH6, Q9NQM5, Q9NTX3, Q9UJ76, Q9UMG6, Q9Y4L4	Gene names	COL4A6
Domain Architecture
Description	Collagen alpha-6(IV) chain precursor.

NU214_HUMAN
NC score	0.028914 (rank : 50)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	110	Target Neighborhood Hits	657	Shared Neighborhood Hits	22
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

C1QC_MOUSE
NC score	0.028849 (rank : 51)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	110	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	Q02105	Gene names	C1qc, C1qg
Domain Architecture
Description	Complement C1q subcomponent subunit C precursor.

CHD1_HUMAN
NC score	0.028796 (rank : 52)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	110	Target Neighborhood Hits	337	Shared Neighborhood Hits	12
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

COAA1_HUMAN
NC score	0.028621 (rank : 53)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	110	Target Neighborhood Hits	316	Shared Neighborhood Hits	19
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

CO5A1_MOUSE
NC score	0.027985 (rank : 54)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	110	Target Neighborhood Hits	419	Shared Neighborhood Hits	18
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CO5A1_HUMAN
NC score	0.027971 (rank : 55)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	110	Target Neighborhood Hits	434	Shared Neighborhood Hits	19
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

PO121_MOUSE
NC score	0.027670 (rank : 56)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	110	Target Neighborhood Hits	345	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

GOGA2_HUMAN
NC score	0.027634 (rank : 57)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	110	Target Neighborhood Hits	856	Shared Neighborhood Hits	14
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

CHD1_MOUSE
NC score	0.027349 (rank : 58)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	110	Target Neighborhood Hits	266	Shared Neighborhood Hits	13
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

NCOR2_MOUSE
NC score	0.026823 (rank : 59)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	110	Target Neighborhood Hits	790	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

CO7A1_HUMAN
NC score	0.024825 (rank : 60)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	110	Target Neighborhood Hits	807	Shared Neighborhood Hits	17
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

SFR17_HUMAN
NC score	0.024562 (rank : 61)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	110	Target Neighborhood Hits	325	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

MAP1B_MOUSE
NC score	0.024159 (rank : 62)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	110	Target Neighborhood Hits	977	Shared Neighborhood Hits	29
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

ECHB_MOUSE
NC score	0.023229 (rank : 63)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	110	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JY0, Q3TEH9, Q8BJI5, Q8BJM0, Q8BK52	Gene names	Hadhb
Domain Architecture	No domain graphic available
Description	Trifunctional enzyme subunit beta, mitochondrial precursor (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)].

FOXP1_HUMAN
NC score	0.023162 (rank : 64)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	110	Target Neighborhood Hits	168	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H334, Q9H332, Q9H333, Q9P0R1	Gene names	FOXP1
Domain Architecture
Description	Forkhead box protein P1.

NFH_MOUSE
NC score	0.023027 (rank : 65)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	110	Target Neighborhood Hits	2247	Shared Neighborhood Hits	58
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OSTP_MOUSE
NC score	0.022733 (rank : 66)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	110	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P10923, P19008	Gene names	Spp1, Eta-1, Op, Spp-1
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Minopontin) (Early T-lymphocyte activation 1 protein) (2AR) (Calcium oxalate crystal growth inhibitor protein).

ZCH14_HUMAN
NC score	0.022430 (rank : 67)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	110	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

UBE4B_HUMAN
NC score	0.022311 (rank : 68)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	110	Target Neighborhood Hits	158	Shared Neighborhood Hits	8
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

AP3B1_HUMAN
NC score	0.022307 (rank : 69)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	110	Target Neighborhood Hits	283	Shared Neighborhood Hits	12
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

SDC3_MOUSE
NC score	0.021567 (rank : 70)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	110	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

FOXP1_MOUSE
NC score	0.020943 (rank : 71)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	110	Target Neighborhood Hits	241	Shared Neighborhood Hits	7
SwissProt Accessions	P58462	Gene names	Foxp1
Domain Architecture
Description	Forkhead box protein P1 (Forkhead-related transcription factor 1).

ECHB_HUMAN
NC score	0.020864 (rank : 72)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	110	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P55084, O14969, Q53TA6, Q96C77, Q9H3F5	Gene names	HADHB
Domain Architecture
Description	Trifunctional enzyme subunit beta, mitochondrial precursor (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)].

NCOA2_MOUSE
NC score	0.020486 (rank : 73)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	110	Target Neighborhood Hits	281	Shared Neighborhood Hits	21
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

MUC5B_HUMAN
NC score	0.020275 (rank : 74)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	110	Target Neighborhood Hits	1020	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

PEX19_MOUSE
NC score	0.019697 (rank : 75)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	110	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCI5, Q8CEE1, Q921H0, Q9CZC1, Q9QUQ1	Gene names	Pex19, Pxf
Domain Architecture	No domain graphic available
Description	Peroxisomal biogenesis factor 19 (Peroxin-19) (Peroxisomal farnesylated protein) (PxF).

UBP32_HUMAN
NC score	0.018471 (rank : 76)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	110	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

MINT_MOUSE
NC score	0.018228 (rank : 77)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	110	Target Neighborhood Hits	1514	Shared Neighborhood Hits	43
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NCOA2_HUMAN
NC score	0.017984 (rank : 78)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	110	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

DACH1_MOUSE
NC score	0.017739 (rank : 79)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	110	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QYB2, O88716, Q8BPQ0, Q8C8D7, Q9QY47, Q9R218, Q9Z0Y5	Gene names	Dach1, Dach
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

S6OS1_MOUSE
NC score	0.016728 (rank : 80)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	110	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CTN5, Q9D5F5, Q9D5Y9	Gene names	Six6os1
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

LIMA1_HUMAN
NC score	0.015468 (rank : 81)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	110	Target Neighborhood Hits	309	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

MACF4_HUMAN
NC score	0.015363 (rank : 82)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	110	Target Neighborhood Hits	1321	Shared Neighborhood Hits	25
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

UBF1_HUMAN
NC score	0.015356 (rank : 83)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	110	Target Neighborhood Hits	415	Shared Neighborhood Hits	10
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

HUWE1_MOUSE
NC score	0.014407 (rank : 84)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	110	Target Neighborhood Hits	406	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

PHF2_HUMAN
NC score	0.013029 (rank : 85)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	110	Target Neighborhood Hits	208	Shared Neighborhood Hits	11
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

SRPK1_HUMAN
NC score	0.012783 (rank : 86)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	110	Target Neighborhood Hits	706	Shared Neighborhood Hits	15
SwissProt Accessions	Q96SB4, Q12890, Q5R364, Q5R365, Q8IY12	Gene names	SRPK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SRPK1 (EC 2.7.11.1) (Serine/arginine- rich protein-specific kinase 1) (SR-protein-specific kinase 1) (SFRS protein kinase 1).

DJBP_MOUSE
NC score	0.011936 (rank : 87)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	110	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

MAGC1_HUMAN
NC score	0.011481 (rank : 88)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	110	Target Neighborhood Hits	431	Shared Neighborhood Hits	12
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MACF1_HUMAN
NC score	0.011418 (rank : 89)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	110	Target Neighborhood Hits	1341	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACOI_HUMAN
NC score	0.011399 (rank : 90)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	110	Target Neighborhood Hits	650	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

SCN5A_HUMAN
NC score	0.009876 (rank : 91)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	110	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

FYCO1_MOUSE
NC score	0.009853 (rank : 92)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	110	Target Neighborhood Hits	1059	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

AP4E1_HUMAN
NC score	0.009733 (rank : 93)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	110	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

SYN1_MOUSE
NC score	0.009600 (rank : 94)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	110	Target Neighborhood Hits	363	Shared Neighborhood Hits	12
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

KAISO_HUMAN
NC score	0.007792 (rank : 95)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	110	Target Neighborhood Hits	840	Shared Neighborhood Hits	8
SwissProt Accessions	Q86T24, O00319, Q7Z361, Q8IVP6, Q8N3P0	Gene names	ZBTB33, KAISO, ZNF348
Domain Architecture	No domain graphic available
Description	Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33).

GIT2_MOUSE
NC score	0.007531 (rank : 96)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	110	Target Neighborhood Hits	323	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

KCNA6_MOUSE
NC score	0.006948 (rank : 97)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	110	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

TGFR2_MOUSE
NC score	0.005784 (rank : 98)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	110	Target Neighborhood Hits	748	Shared Neighborhood Hits	7
SwissProt Accessions	Q62312, Q63947	Gene names	Tgfbr2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

ARHGC_HUMAN
NC score	0.005717 (rank : 99)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	110	Target Neighborhood Hits	351	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

PLCB1_MOUSE
NC score	0.005654 (rank : 100)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	110	Target Neighborhood Hits	531	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

CADH1_MOUSE
NC score	0.004218 (rank : 101)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	110	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	P09803, Q61377	Gene names	Cdh1
Domain Architecture
Description	Epithelial-cadherin precursor (E-cadherin) (Uvomorulin) (Cadherin-1) (ARC-1) (CD324 antigen) [Contains: E-Cad/CTF1; E-Cad/CTF2; E- Cad/CTF3].

TNIK_HUMAN
NC score	0.004074 (rank : 102)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	110	Target Neighborhood Hits	1570	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

WNK4_HUMAN
NC score	0.004071 (rank : 103)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	110	Target Neighborhood Hits	1043	Shared Neighborhood Hits	16
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

RXRG_HUMAN
NC score	0.003888 (rank : 104)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	110	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

M3K2_MOUSE
NC score	0.002846 (rank : 105)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	110	Target Neighborhood Hits	846	Shared Neighborhood Hits	8
SwissProt Accessions	Q61083	Gene names	Map3k2, Mekk2
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 2 (EC 2.7.11.25) (MAPK/ERK kinase kinase 2) (MEK kinase 2) (MEKK 2).

MK10_HUMAN
NC score	0.002674 (rank : 106)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	110	Target Neighborhood Hits	836	Shared Neighborhood Hits	8
SwissProt Accessions	P53779, Q15707	Gene names	MAPK10, JNK3, JNK3A, PRKM10
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

MK10_MOUSE
NC score	0.002562 (rank : 107)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	110	Target Neighborhood Hits	849	Shared Neighborhood Hits	10
SwissProt Accessions	Q61831, Q9R0U6	Gene names	Mapk10, Jnk3, Prkm10, Serk2
Domain Architecture
Description	Mitogen-activated protein kinase 10 (EC 2.7.11.24) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12).

PRDM9_HUMAN
NC score	0.002018 (rank : 108)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	110	Target Neighborhood Hits	750	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQV7	Gene names	PRDM9, PFM6
Domain Architecture
Description	PR domain zinc finger protein 9 (PR domain-containing protein 9).

SP2_HUMAN
NC score	0.000878 (rank : 109)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	110	Target Neighborhood Hits	747	Shared Neighborhood Hits	6
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.

MTF1_HUMAN
NC score	0.000551 (rank : 110)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	110	Target Neighborhood Hits	814	Shared Neighborhood Hits	9
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).