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Network neighborhood for query Sequence : AP4E1_HUMAN

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AP4E1_HUMAN
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

AP4E1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	57	Target Neighborhood Hits	57	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP4E1_MOUSE
θ value	0 (rank : 2)	NC score	0.995346 (rank : 2)
Query Neighborhood Hits	57	Target Neighborhood Hits	59	Shared Neighborhood Hits	36
SwissProt Accessions	Q80V94	Gene names	Ap4e1
Domain Architecture	No domain graphic available
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP1G1_HUMAN
θ value	1.15626e-55 (rank : 3)	NC score	0.837974 (rank : 4)
Query Neighborhood Hits	57	Target Neighborhood Hits	65	Shared Neighborhood Hits	25
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_MOUSE
θ value	1.15626e-55 (rank : 4)	NC score	0.840682 (rank : 3)
Query Neighborhood Hits	57	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G2_MOUSE
θ value	2.75849e-49 (rank : 5)	NC score	0.830024 (rank : 6)
Query Neighborhood Hits	57	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP1G2_HUMAN
θ value	1.56636e-44 (rank : 6)	NC score	0.830530 (rank : 5)
Query Neighborhood Hits	57	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP2A1_HUMAN
θ value	1.12253e-42 (rank : 7)	NC score	0.814428 (rank : 7)
Query Neighborhood Hits	57	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A1_MOUSE
θ value	1.46607e-42 (rank : 8)	NC score	0.809083 (rank : 11)
Query Neighborhood Hits	57	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A2_HUMAN
θ value	3.61106e-41 (rank : 9)	NC score	0.810742 (rank : 8)
Query Neighborhood Hits	57	Target Neighborhood Hits	39	Shared Neighborhood Hits	16
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP2A2_MOUSE
θ value	8.04462e-41 (rank : 10)	NC score	0.809434 (rank : 10)
Query Neighborhood Hits	57	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP3D1_MOUSE
θ value	3.99248e-40 (rank : 11)	NC score	0.809650 (rank : 9)
Query Neighborhood Hits	57	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

AP3D1_HUMAN
θ value	1.6774e-38 (rank : 12)	NC score	0.783073 (rank : 12)
Query Neighborhood Hits	57	Target Neighborhood Hits	254	Shared Neighborhood Hits	29
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

AP1B1_MOUSE
θ value	2.13673e-09 (rank : 13)	NC score	0.469197 (rank : 13)
Query Neighborhood Hits	57	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	O35643, Q922E2	Gene names	Ap1b1, Adtb1
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

AP1B1_HUMAN
θ value	2.79066e-09 (rank : 14)	NC score	0.467699 (rank : 14)
Query Neighborhood Hits	57	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	Q10567, P78436	Gene names	AP1B1, ADTB1, BAM22
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

COPB_HUMAN
θ value	4.0297e-08 (rank : 15)	NC score	0.413888 (rank : 18)
Query Neighborhood Hits	57	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	P53618, Q6GTT7, Q9NTK2, Q9UNW7	Gene names	COPB1, COPB
Domain Architecture
Description	Coatomer subunit beta (Beta-coat protein) (Beta-COP).

COPB_MOUSE
θ value	4.0297e-08 (rank : 16)	NC score	0.414214 (rank : 17)
Query Neighborhood Hits	57	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JIF7	Gene names	Copb1, Copb
Domain Architecture
Description	Coatomer subunit beta (Beta-coat protein) (Beta-COP).

AP2B1_HUMAN
θ value	8.97725e-08 (rank : 17)	NC score	0.458027 (rank : 16)
Query Neighborhood Hits	57	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_MOUSE
θ value	8.97725e-08 (rank : 18)	NC score	0.458041 (rank : 15)
Query Neighborhood Hits	57	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP3B1_HUMAN
θ value	0.000158464 (rank : 19)	NC score	0.292749 (rank : 19)
Query Neighborhood Hits	57	Target Neighborhood Hits	283	Shared Neighborhood Hits	23
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP3B1_MOUSE
θ value	0.000270298 (rank : 20)	NC score	0.291879 (rank : 20)
Query Neighborhood Hits	57	Target Neighborhood Hits	302	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP3B2_HUMAN
θ value	0.0252991 (rank : 21)	NC score	0.246941 (rank : 22)
Query Neighborhood Hits	57	Target Neighborhood Hits	246	Shared Neighborhood Hits	19
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

AP3B2_MOUSE
θ value	0.0252991 (rank : 22)	NC score	0.245681 (rank : 23)
Query Neighborhood Hits	57	Target Neighborhood Hits	246	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

COPG_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.162392 (rank : 27)
Query Neighborhood Hits	57	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y678	Gene names	COPG
Domain Architecture
Description	Coatomer subunit gamma (Gamma-coat protein) (Gamma-COP).

SUFU_HUMAN
θ value	0.21417 (rank : 24)	NC score	0.057557 (rank : 38)
Query Neighborhood Hits	57	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMX1, Q7LCP7, Q9NT90, Q9NZ07, Q9UHK2, Q9UHM8, Q9UMY0	Gene names	SUFU
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog (SUFUH).

COPG2_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.178279 (rank : 26)
Query Neighborhood Hits	57	Target Neighborhood Hits	33	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBF2	Gene names	COPG2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

DDX27_HUMAN
θ value	0.279714 (rank : 26)	NC score	0.010794 (rank : 53)
Query Neighborhood Hits	57	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

COPG2_MOUSE
θ value	0.365318 (rank : 27)	NC score	0.186652 (rank : 25)
Query Neighborhood Hits	57	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

TNPO1_HUMAN
θ value	0.47712 (rank : 28)	NC score	0.061008 (rank : 37)
Query Neighborhood Hits	57	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	0.47712 (rank : 29)	NC score	0.061081 (rank : 36)
Query Neighborhood Hits	57	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO2_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.061494 (rank : 34)
Query Neighborhood Hits	57	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	0.47712 (rank : 31)	NC score	0.061406 (rank : 35)
Query Neighborhood Hits	57	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

NOP5_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.028641 (rank : 43)
Query Neighborhood Hits	57	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2X3, Q6PK08, Q9P036, Q9UFN3	Gene names	NOP5
Domain Architecture
Description	Nucleolar protein NOP5 (Nucleolar protein 5) (NOP58).

CEP35_HUMAN
θ value	0.813845 (rank : 33)	NC score	0.029989 (rank : 42)
Query Neighborhood Hits	57	Target Neighborhood Hits	811	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

OLR1_MOUSE
θ value	0.813845 (rank : 34)	NC score	0.012770 (rank : 50)
Query Neighborhood Hits	57	Target Neighborhood Hits	596	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

APOA4_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.025811 (rank : 45)
Query Neighborhood Hits	57	Target Neighborhood Hits	399	Shared Neighborhood Hits	6
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

CI039_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.008230 (rank : 57)
Query Neighborhood Hits	57	Target Neighborhood Hits	1171	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

SUFU_MOUSE
θ value	1.38821 (rank : 37)	NC score	0.044245 (rank : 39)
Query Neighborhood Hits	57	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0P7, Q8C8B4, Q99JG0, Q9D521, Q9JLU1	Gene names	Sufu
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog.

MLL3_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.016409 (rank : 47)
Query Neighborhood Hits	57	Target Neighborhood Hits	1644	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

BCL6_HUMAN
θ value	3.0926 (rank : 39)	NC score	-0.001440 (rank : 64)
Query Neighborhood Hits	57	Target Neighborhood Hits	922	Shared Neighborhood Hits	3
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

PP1R8_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.026884 (rank : 44)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

BBS7_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.036700 (rank : 41)
Query Neighborhood Hits	57	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWZ6, Q4W5P8, Q8N581, Q9NVI4	Gene names	BBS7, BBS2L1
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 7 protein (BBS2-like protein 1).

BBS7_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.036830 (rank : 40)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2G4, Q8C7G3, Q8CH00, Q9CXC2	Gene names	Bbs7, Bbs2l1
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1).

RFC1_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.015012 (rank : 48)
Query Neighborhood Hits	57	Target Neighborhood Hits	352	Shared Neighborhood Hits	3
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

RPGR_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.012144 (rank : 51)
Query Neighborhood Hits	57	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

C8AP2_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.014193 (rank : 49)
Query Neighborhood Hits	57	Target Neighborhood Hits	405	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

FMN2_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.007376 (rank : 58)
Query Neighborhood Hits	57	Target Neighborhood Hits	349	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

MMRN2_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.010226 (rank : 55)
Query Neighborhood Hits	57	Target Neighborhood Hits	400	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

SELS_MOUSE
θ value	5.27518 (rank : 48)	NC score	0.019189 (rank : 46)
Query Neighborhood Hits	57	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BCZ4, Q921S1, Q9DB55	Gene names	Sels, H47, Vimp
Domain Architecture
Description	Selenoprotein S (VCP-interacting membrane protein) (Minor histocompatibility antigen H47).

CCD39_MOUSE
θ value	6.88961 (rank : 49)	NC score	0.002164 (rank : 63)
Query Neighborhood Hits	57	Target Neighborhood Hits	1026	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CJ006_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.011700 (rank : 52)
Query Neighborhood Hits	57	Target Neighborhood Hits	122	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX21, Q5W0L8, Q9NPE8	Gene names	C10orf6
Domain Architecture	No domain graphic available
Description	Protein C10orf6.

IFNA2_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.004360 (rank : 60)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P01563, P01564, Q14606, Q96KI6	Gene names	IFNA2
Domain Architecture
Description	Interferon alpha-2 precursor (Interferon alpha-A) (LeIF A).

STX12_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.006305 (rank : 59)
Query Neighborhood Hits	57	Target Neighborhood Hits	283	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

ZNF8_HUMAN
θ value	6.88961 (rank : 53)	NC score	-0.002361 (rank : 65)
Query Neighborhood Hits	57	Target Neighborhood Hits	748	Shared Neighborhood Hits	3
SwissProt Accessions	P17098, Q6PI99	Gene names	ZNF8
Domain Architecture	No domain graphic available
Description	Zinc finger protein 8 (Zinc finger protein HF.18).

CLMN_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.003480 (rank : 61)
Query Neighborhood Hits	57	Target Neighborhood Hits	205	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

NRIP1_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.009733 (rank : 56)
Query Neighborhood Hits	57	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

NUFP2_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.010473 (rank : 54)
Query Neighborhood Hits	57	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z417, Q9P2M5	Gene names	NUFIP2, KIAA1321, PIG1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 2 (FMRP- interacting protein 2) (82 kDa FMRP-interacting protein) (82-FIP) (Proliferation-inducing gene 1 protein).

TR107_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.002523 (rank : 62)
Query Neighborhood Hits	57	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	Q7M725, Q71QD3	Gene names	Tas2r107, T2r4, T2r43
Domain Architecture	No domain graphic available
Description	Taste receptor type 2 member 107 (T2R107) (mT2R43) (T2R4) (STC5-1).

AP4B1_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.233926 (rank : 24)
Query Neighborhood Hits	57	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6B7	Gene names	AP4B1
Domain Architecture
Description	AP-4 complex subunit beta-1 (Adapter-related protein complex 4 beta 1 subunit) (Beta subunit of AP-4) (AP-4 adapter complex beta subunit).

AP4B1_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.256861 (rank : 21)
Query Neighborhood Hits	57	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WV76	Gene names	Ap4b1
Domain Architecture
Description	AP-4 complex subunit beta-1 (Adapter-related protein complex 4 beta-1 subunit) (Beta subunit of AP-4) (AP-4 adapter complex beta subunit).

GGA1_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.095177 (rank : 32)
Query Neighborhood Hits	57	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA1_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.090660 (rank : 33)
Query Neighborhood Hits	57	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA2_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.108309 (rank : 29)
Query Neighborhood Hits	57	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA2_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.111394 (rank : 28)
Query Neighborhood Hits	57	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

GGA3_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.103789 (rank : 31)
Query Neighborhood Hits	57	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA3_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.103845 (rank : 30)
Query Neighborhood Hits	57	Target Neighborhood Hits	148	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

Hits sorted by NC score

AP4E1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	57	Target Neighborhood Hits	57	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP4E1_MOUSE
NC score	0.995346 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	57	Target Neighborhood Hits	59	Shared Neighborhood Hits	36
SwissProt Accessions	Q80V94	Gene names	Ap4e1
Domain Architecture	No domain graphic available
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP1G1_MOUSE
NC score	0.840682 (rank : 3)	θ value	1.15626e-55 (rank : 4)
Query Neighborhood Hits	57	Target Neighborhood Hits	67	Shared Neighborhood Hits	25
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_HUMAN
NC score	0.837974 (rank : 4)	θ value	1.15626e-55 (rank : 3)
Query Neighborhood Hits	57	Target Neighborhood Hits	65	Shared Neighborhood Hits	25
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G2_HUMAN
NC score	0.830530 (rank : 5)	θ value	1.56636e-44 (rank : 6)
Query Neighborhood Hits	57	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP1G2_MOUSE
NC score	0.830024 (rank : 6)	θ value	2.75849e-49 (rank : 5)
Query Neighborhood Hits	57	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP2A1_HUMAN
NC score	0.814428 (rank : 7)	θ value	1.12253e-42 (rank : 7)
Query Neighborhood Hits	57	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A2_HUMAN
NC score	0.810742 (rank : 8)	θ value	3.61106e-41 (rank : 9)
Query Neighborhood Hits	57	Target Neighborhood Hits	39	Shared Neighborhood Hits	16
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP3D1_MOUSE
NC score	0.809650 (rank : 9)	θ value	3.99248e-40 (rank : 11)
Query Neighborhood Hits	57	Target Neighborhood Hits	144	Shared Neighborhood Hits	25
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

AP2A2_MOUSE
NC score	0.809434 (rank : 10)	θ value	8.04462e-41 (rank : 10)
Query Neighborhood Hits	57	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP2A1_MOUSE
NC score	0.809083 (rank : 11)	θ value	1.46607e-42 (rank : 8)
Query Neighborhood Hits	57	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP3D1_HUMAN
NC score	0.783073 (rank : 12)	θ value	1.6774e-38 (rank : 12)
Query Neighborhood Hits	57	Target Neighborhood Hits	254	Shared Neighborhood Hits	29
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

AP1B1_MOUSE
NC score	0.469197 (rank : 13)	θ value	2.13673e-09 (rank : 13)
Query Neighborhood Hits	57	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	O35643, Q922E2	Gene names	Ap1b1, Adtb1
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

AP1B1_HUMAN
NC score	0.467699 (rank : 14)	θ value	2.79066e-09 (rank : 14)
Query Neighborhood Hits	57	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	Q10567, P78436	Gene names	AP1B1, ADTB1, BAM22
Domain Architecture
Description	AP-1 complex subunit beta-1 (Adapter-related protein complex 1 beta-1 subunit) (Beta-adaptin 1) (Adaptor protein complex AP-1 beta-1 subunit) (Golgi adaptor HA1/AP1 adaptin beta subunit) (Clathrin assembly protein complex 1 beta large chain).

AP2B1_MOUSE
NC score	0.458041 (rank : 15)	θ value	8.97725e-08 (rank : 18)
Query Neighborhood Hits	57	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_HUMAN
NC score	0.458027 (rank : 16)	θ value	8.97725e-08 (rank : 17)
Query Neighborhood Hits	57	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

COPB_MOUSE
NC score	0.414214 (rank : 17)	θ value	4.0297e-08 (rank : 16)
Query Neighborhood Hits	57	Target Neighborhood Hits	50	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JIF7	Gene names	Copb1, Copb
Domain Architecture
Description	Coatomer subunit beta (Beta-coat protein) (Beta-COP).

COPB_HUMAN
NC score	0.413888 (rank : 18)	θ value	4.0297e-08 (rank : 15)
Query Neighborhood Hits	57	Target Neighborhood Hits	47	Shared Neighborhood Hits	22
SwissProt Accessions	P53618, Q6GTT7, Q9NTK2, Q9UNW7	Gene names	COPB1, COPB
Domain Architecture
Description	Coatomer subunit beta (Beta-coat protein) (Beta-COP).

AP3B1_HUMAN
NC score	0.292749 (rank : 19)	θ value	0.000158464 (rank : 19)
Query Neighborhood Hits	57	Target Neighborhood Hits	283	Shared Neighborhood Hits	23
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP3B1_MOUSE
NC score	0.291879 (rank : 20)	θ value	0.000270298 (rank : 20)
Query Neighborhood Hits	57	Target Neighborhood Hits	302	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP4B1_MOUSE
NC score	0.256861 (rank : 21)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	57	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WV76	Gene names	Ap4b1
Domain Architecture
Description	AP-4 complex subunit beta-1 (Adapter-related protein complex 4 beta-1 subunit) (Beta subunit of AP-4) (AP-4 adapter complex beta subunit).

AP3B2_HUMAN
NC score	0.246941 (rank : 22)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	57	Target Neighborhood Hits	246	Shared Neighborhood Hits	19
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

AP3B2_MOUSE
NC score	0.245681 (rank : 23)	θ value	0.0252991 (rank : 22)
Query Neighborhood Hits	57	Target Neighborhood Hits	246	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

AP4B1_HUMAN
NC score	0.233926 (rank : 24)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	57	Target Neighborhood Hits	41	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y6B7	Gene names	AP4B1
Domain Architecture
Description	AP-4 complex subunit beta-1 (Adapter-related protein complex 4 beta 1 subunit) (Beta subunit of AP-4) (AP-4 adapter complex beta subunit).

COPG2_MOUSE
NC score	0.186652 (rank : 25)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	57	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

COPG2_HUMAN
NC score	0.178279 (rank : 26)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	57	Target Neighborhood Hits	33	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UBF2	Gene names	COPG2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

COPG_HUMAN
NC score	0.162392 (rank : 27)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	57	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y678	Gene names	COPG
Domain Architecture
Description	Coatomer subunit gamma (Gamma-coat protein) (Gamma-COP).

GGA2_MOUSE
NC score	0.111394 (rank : 28)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	57	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

GGA2_HUMAN
NC score	0.108309 (rank : 29)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	57	Target Neighborhood Hits	114	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA3_MOUSE
NC score	0.103845 (rank : 30)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	57	Target Neighborhood Hits	148	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA3_HUMAN
NC score	0.103789 (rank : 31)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	57	Target Neighborhood Hits	127	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA1_HUMAN
NC score	0.095177 (rank : 32)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	57	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA1_MOUSE
NC score	0.090660 (rank : 33)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	57	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

TNPO2_HUMAN
NC score	0.061494 (rank : 34)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	57	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
NC score	0.061406 (rank : 35)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	57	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO1_MOUSE
NC score	0.061081 (rank : 36)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	57	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO1_HUMAN
NC score	0.061008 (rank : 37)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	57	Target Neighborhood Hits	64	Shared Neighborhood Hits	6
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

SUFU_HUMAN
NC score	0.057557 (rank : 38)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	57	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMX1, Q7LCP7, Q9NT90, Q9NZ07, Q9UHK2, Q9UHM8, Q9UMY0	Gene names	SUFU
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog (SUFUH).

SUFU_MOUSE
NC score	0.044245 (rank : 39)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	57	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0P7, Q8C8B4, Q99JG0, Q9D521, Q9JLU1	Gene names	Sufu
Domain Architecture	No domain graphic available
Description	Suppressor of fused homolog.

BBS7_MOUSE
NC score	0.036830 (rank : 40)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2G4, Q8C7G3, Q8CH00, Q9CXC2	Gene names	Bbs7, Bbs2l1
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 7 protein homolog (BBS2-like protein 1).

BBS7_HUMAN
NC score	0.036700 (rank : 41)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	57	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWZ6, Q4W5P8, Q8N581, Q9NVI4	Gene names	BBS7, BBS2L1
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 7 protein (BBS2-like protein 1).

CEP35_HUMAN
NC score	0.029989 (rank : 42)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	57	Target Neighborhood Hits	811	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

NOP5_HUMAN
NC score	0.028641 (rank : 43)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	57	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2X3, Q6PK08, Q9P036, Q9UFN3	Gene names	NOP5
Domain Architecture
Description	Nucleolar protein NOP5 (Nucleolar protein 5) (NOP58).

PP1R8_MOUSE
NC score	0.026884 (rank : 44)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3G1, Q8C087	Gene names	Ppp1r8, Nipp1
Domain Architecture	No domain graphic available
Description	Nuclear inhibitor of protein phosphatase 1 (NIPP-1) (Protein phosphatase 1 regulatory inhibitor subunit 8).

APOA4_HUMAN
NC score	0.025811 (rank : 45)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	57	Target Neighborhood Hits	399	Shared Neighborhood Hits	6
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

SELS_MOUSE
NC score	0.019189 (rank : 46)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	57	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BCZ4, Q921S1, Q9DB55	Gene names	Sels, H47, Vimp
Domain Architecture
Description	Selenoprotein S (VCP-interacting membrane protein) (Minor histocompatibility antigen H47).

MLL3_HUMAN
NC score	0.016409 (rank : 47)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	57	Target Neighborhood Hits	1644	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RFC1_HUMAN
NC score	0.015012 (rank : 48)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	57	Target Neighborhood Hits	352	Shared Neighborhood Hits	3
SwissProt Accessions	P35251, Q5XKF5, Q6PKU0, Q86V41, Q86V46	Gene names	RFC1, RFC140
Domain Architecture
Description	Replication factor C subunit 1 (Replication factor C large subunit) (RF-C 140 kDa subunit) (Activator 1 140 kDa subunit) (Activator 1 large subunit) (A1 140 kDa subunit) (DNA-binding protein PO-GA).

C8AP2_MOUSE
NC score	0.014193 (rank : 49)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	57	Target Neighborhood Hits	405	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

OLR1_MOUSE
NC score	0.012770 (rank : 50)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	57	Target Neighborhood Hits	596	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

RPGR_HUMAN
NC score	0.012144 (rank : 51)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	57	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

CJ006_HUMAN
NC score	0.011700 (rank : 52)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	57	Target Neighborhood Hits	122	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IX21, Q5W0L8, Q9NPE8	Gene names	C10orf6
Domain Architecture	No domain graphic available
Description	Protein C10orf6.

DDX27_HUMAN
NC score	0.010794 (rank : 53)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	57	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q96GQ7, Q5VXM7, Q8WYG4, Q969N7, Q96F57, Q96L97, Q9BWY9, Q9BXF0, Q9H990, Q9NWU3, Q9P0C2, Q9UGD6	Gene names	DDX27, RHLP
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX27 (EC 3.6.1.-) (DEAD box protein 27).

NUFP2_HUMAN
NC score	0.010473 (rank : 54)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	57	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z417, Q9P2M5	Gene names	NUFIP2, KIAA1321, PIG1
Domain Architecture	No domain graphic available
Description	Nuclear fragile X mental retardation-interacting protein 2 (FMRP- interacting protein 2) (82 kDa FMRP-interacting protein) (82-FIP) (Proliferation-inducing gene 1 protein).

MMRN2_HUMAN
NC score	0.010226 (rank : 55)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	57	Target Neighborhood Hits	400	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8L6, Q6P2N2	Gene names	MMRN2, EMILIN3
Domain Architecture
Description	Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit).

NRIP1_MOUSE
NC score	0.009733 (rank : 56)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	57	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CBD1, Q8C3Y8, Q9Z2K2	Gene names	Nrip1
Domain Architecture	No domain graphic available
Description	Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140).

CI039_HUMAN
NC score	0.008230 (rank : 57)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	57	Target Neighborhood Hits	1171	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

FMN2_MOUSE
NC score	0.007376 (rank : 58)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	57	Target Neighborhood Hits	349	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

STX12_MOUSE
NC score	0.006305 (rank : 59)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	57	Target Neighborhood Hits	283	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ER00, Q3UIV9, Q921T9	Gene names	Stx12
Domain Architecture
Description	Syntaxin-12.

IFNA2_HUMAN
NC score	0.004360 (rank : 60)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P01563, P01564, Q14606, Q96KI6	Gene names	IFNA2
Domain Architecture
Description	Interferon alpha-2 precursor (Interferon alpha-A) (LeIF A).

CLMN_HUMAN
NC score	0.003480 (rank : 61)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	57	Target Neighborhood Hits	205	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

TR107_MOUSE
NC score	0.002523 (rank : 62)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	57	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	Q7M725, Q71QD3	Gene names	Tas2r107, T2r4, T2r43
Domain Architecture	No domain graphic available
Description	Taste receptor type 2 member 107 (T2R107) (mT2R43) (T2R4) (STC5-1).

CCD39_MOUSE
NC score	0.002164 (rank : 63)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	57	Target Neighborhood Hits	1026	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

BCL6_HUMAN
NC score	-0.001440 (rank : 64)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	57	Target Neighborhood Hits	922	Shared Neighborhood Hits	3
SwissProt Accessions	P41182	Gene names	BCL6, BCL5, LAZ3, ZBTB27, ZNF51
Domain Architecture
Description	B-cell lymphoma 6 protein (BCL-6) (Zinc finger protein 51) (LAZ-3 protein) (BCL-5) (Zinc finger and BTB domain-containing protein 27).

ZNF8_HUMAN
NC score	-0.002361 (rank : 65)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	57	Target Neighborhood Hits	748	Shared Neighborhood Hits	3
SwissProt Accessions	P17098, Q6PI99	Gene names	ZNF8
Domain Architecture	No domain graphic available
Description	Zinc finger protein 8 (Zinc finger protein HF.18).