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Network neighborhood for query Sequence : GGA2_MOUSE

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GGA2_MOUSE
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GGA2_HUMAN
θ value	0 (rank : 1)	NC score	0.988972 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	114	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

GGA1_MOUSE
θ value	3.4095e-124 (rank : 3)	NC score	0.952732 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	128	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA1_HUMAN
θ value	2.06847e-121 (rank : 4)	NC score	0.952646 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	169	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA3_HUMAN
θ value	2.02215e-84 (rank : 5)	NC score	0.936838 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	127	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA3_MOUSE
θ value	1.00358e-83 (rank : 6)	NC score	0.925488 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	148	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

TM1L1_MOUSE
θ value	3.40345e-15 (rank : 7)	NC score	0.645011 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

AP1G1_HUMAN
θ value	7.58209e-15 (rank : 8)	NC score	0.396207 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

TOM1_MOUSE
θ value	1.68911e-14 (rank : 9)	NC score	0.662699 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

AP1G1_MOUSE
θ value	3.76295e-14 (rank : 10)	NC score	0.388645 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

TOM1_HUMAN
θ value	4.91457e-14 (rank : 11)	NC score	0.657628 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	16
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

AP1G2_MOUSE
θ value	1.86753e-13 (rank : 12)	NC score	0.381169 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

TM1L1_HUMAN
θ value	1.86753e-13 (rank : 13)	NC score	0.631511 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

AP1G2_HUMAN
θ value	1.47974e-10 (rank : 14)	NC score	0.371195 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

HGS_MOUSE
θ value	1.9326e-10 (rank : 15)	NC score	0.391938 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	589	Shared Neighborhood Hits	25
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HGS_HUMAN
θ value	3.29651e-10 (rank : 16)	NC score	0.392918 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	517	Shared Neighborhood Hits	23
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

STAM2_HUMAN
θ value	1.63604e-09 (rank : 17)	NC score	0.392372 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
θ value	3.64472e-09 (rank : 18)	NC score	0.377008 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	285	Shared Neighborhood Hits	18
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STAM1_HUMAN
θ value	1.06045e-08 (rank : 19)	NC score	0.381971 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	271	Shared Neighborhood Hits	18
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	1.38499e-08 (rank : 20)	NC score	0.377046 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

SRBP1_HUMAN
θ value	0.0961366 (rank : 21)	NC score	0.048823 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

K0555_HUMAN
θ value	0.125558 (rank : 22)	NC score	0.022184 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	880	Shared Neighborhood Hits	11
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

HNF1A_HUMAN
θ value	0.163984 (rank : 23)	NC score	0.051917 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

HNF1A_MOUSE
θ value	0.21417 (rank : 24)	NC score	0.045457 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

SMCA4_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.022361 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	597	Shared Neighborhood Hits	9
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

IRX4_MOUSE
θ value	0.47712 (rank : 26)	NC score	0.023125 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY61	Gene names	Irx4, Irxa3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

RAPH1_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.024654 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	593	Shared Neighborhood Hits	6
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

ABL1_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.006093 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	1178	Shared Neighborhood Hits	13
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

SWP70_MOUSE
θ value	0.813845 (rank : 29)	NC score	0.017765 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	1097	Shared Neighborhood Hits	12
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CCD96_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.022615 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	704	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

LDB3_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.018824 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	497	Shared Neighborhood Hits	11
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

SYNE1_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.011434 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	1484	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

COBA2_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.005837 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	408	Shared Neighborhood Hits	3
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

PASK_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.000872 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	857	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).

SREC2_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.004932 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	605	Shared Neighborhood Hits	4
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

ALEX_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.047946 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CCDC7_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.022133 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	253	Shared Neighborhood Hits	5
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

SPTN2_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.011889 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	535	Shared Neighborhood Hits	10
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

T240L_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.024448 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	132	Shared Neighborhood Hits	4
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

T240L_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.024647 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

GNDS_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.010598 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	201	Shared Neighborhood Hits	4
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

LRC8C_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.007860 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R502, Q3TEP9, Q8C296, Q8R0N7, Q8R3G5	Gene names	Lrrc8c, Ad158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

RUNX2_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.031620 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.031732 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

ITSN2_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.020473 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	1173	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

LDB3_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.012600 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	510	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

RGS3_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.014554 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	1375	Shared Neighborhood Hits	20
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

AP2B1_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.049631 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.049634 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

CEP68_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.014816 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

CRBB1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.009532 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P53674	Gene names	CRYBB1
Domain Architecture
Description	Beta crystallin B1.

MRP2_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.005946 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

PEX1_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.005526 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

CD248_MOUSE
θ value	6.88961 (rank : 54)	NC score	0.004769 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	578	Shared Neighborhood Hits	11
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CN092_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.023309 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

SORC3_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.005899 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

CE290_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.014044 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	1553	Shared Neighborhood Hits	18
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

KLC4_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.003923 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	336	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

RFIP3_HUMAN
θ value	8.99809 (rank : 59)	NC score	0.013471 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	1055	Shared Neighborhood Hits	16
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

SPB6_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.001366 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	P35237, Q96J44	Gene names	SERPINB6, PI6, PTI
Domain Architecture
Description	Serpin B6 (Placental thrombin inhibitor) (Cytoplasmic antiproteinase) (CAP) (Protease inhibitor 6) (PI-6).

AP2A1_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.110720 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A1_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.108116 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A2_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.107777 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP2A2_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.107941 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP3D1_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.095340 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	254	Shared Neighborhood Hits	6
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

AP3D1_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.100562 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

AP4E1_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.111394 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP4E1_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.110644 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q80V94	Gene names	Ap4e1
Domain Architecture	No domain graphic available
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

Hits sorted by NC score

GGA2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

GGA2_HUMAN
NC score	0.988972 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	114	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA1_MOUSE
NC score	0.952732 (rank : 3)	θ value	3.4095e-124 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	128	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA1_HUMAN
NC score	0.952646 (rank : 4)	θ value	2.06847e-121 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	169	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA3_HUMAN
NC score	0.936838 (rank : 5)	θ value	2.02215e-84 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	127	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA3_MOUSE
NC score	0.925488 (rank : 6)	θ value	1.00358e-83 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	148	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

TOM1_MOUSE
NC score	0.662699 (rank : 7)	θ value	1.68911e-14 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

TOM1_HUMAN
NC score	0.657628 (rank : 8)	θ value	4.91457e-14 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	55	Shared Neighborhood Hits	16
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

TM1L1_MOUSE
NC score	0.645011 (rank : 9)	θ value	3.40345e-15 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

TM1L1_HUMAN
NC score	0.631511 (rank : 10)	θ value	1.86753e-13 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

AP1G1_HUMAN
NC score	0.396207 (rank : 11)	θ value	7.58209e-15 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	65	Shared Neighborhood Hits	12
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

HGS_HUMAN
NC score	0.392918 (rank : 12)	θ value	3.29651e-10 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	517	Shared Neighborhood Hits	23
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

STAM2_HUMAN
NC score	0.392372 (rank : 13)	θ value	1.63604e-09 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	288	Shared Neighborhood Hits	18
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

HGS_MOUSE
NC score	0.391938 (rank : 14)	θ value	1.9326e-10 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	589	Shared Neighborhood Hits	25
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

AP1G1_MOUSE
NC score	0.388645 (rank : 15)	θ value	3.76295e-14 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	67	Shared Neighborhood Hits	13
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

STAM1_HUMAN
NC score	0.381971 (rank : 16)	θ value	1.06045e-08 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	271	Shared Neighborhood Hits	18
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

AP1G2_MOUSE
NC score	0.381169 (rank : 17)	θ value	1.86753e-13 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	52	Shared Neighborhood Hits	12
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

STAM1_MOUSE
NC score	0.377046 (rank : 18)	θ value	1.38499e-08 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	273	Shared Neighborhood Hits	18
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
NC score	0.377008 (rank : 19)	θ value	3.64472e-09 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	285	Shared Neighborhood Hits	18
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

AP1G2_HUMAN
NC score	0.371195 (rank : 20)	θ value	1.47974e-10 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP4E1_HUMAN
NC score	0.111394 (rank : 21)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPM8, Q9Y588	Gene names	AP4E1
Domain Architecture
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP2A1_HUMAN
NC score	0.110720 (rank : 22)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP4E1_MOUSE
NC score	0.110644 (rank : 23)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	59	Shared Neighborhood Hits	6
SwissProt Accessions	Q80V94	Gene names	Ap4e1
Domain Architecture	No domain graphic available
Description	AP-4 complex subunit epsilon-1 (Adapter-related protein complex 4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit).

AP2A1_MOUSE
NC score	0.108116 (rank : 24)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

AP2A2_MOUSE
NC score	0.107941 (rank : 25)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

AP2A2_HUMAN
NC score	0.107777 (rank : 26)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP3D1_MOUSE
NC score	0.100562 (rank : 27)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

AP3D1_HUMAN
NC score	0.095340 (rank : 28)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	254	Shared Neighborhood Hits	6
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

HNF1A_HUMAN
NC score	0.051917 (rank : 29)	θ value	0.163984 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	P20823, Q99861	Gene names	TCF1, HNF1A
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1).

AP2B1_MOUSE
NC score	0.049634 (rank : 30)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_HUMAN
NC score	0.049631 (rank : 31)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

SRBP1_HUMAN
NC score	0.048823 (rank : 32)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ALEX_MOUSE
NC score	0.047946 (rank : 33)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

HNF1A_MOUSE
NC score	0.045457 (rank : 34)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

RUNX2_MOUSE
NC score	0.031732 (rank : 35)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q08775, O35183, Q08776, Q9JLN0, Q9QUQ6, Q9QY29, Q9R0U4, Q9Z2J7	Gene names	Runx2, Aml3, Cbfa1, Osf2, Pebp2a
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RUNX2_HUMAN
NC score	0.031620 (rank : 36)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q13950, O14614, O14615, O95181	Gene names	RUNX2, AML3, CBFA1, OSF2, PEBP2A
Domain Architecture
Description	Runt-related transcription factor 2 (Core-binding factor, alpha 1 subunit) (CBF-alpha 1) (Acute myeloid leukemia 3 protein) (Oncogene AML-3) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEBP2-alpha A) (PEA2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit) (Osteoblast- specific transcription factor 2) (OSF-2).

RAPH1_HUMAN
NC score	0.024654 (rank : 37)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	593	Shared Neighborhood Hits	6
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

T240L_MOUSE
NC score	0.024647 (rank : 38)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

T240L_HUMAN
NC score	0.024448 (rank : 39)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	132	Shared Neighborhood Hits	4
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

CN092_MOUSE
NC score	0.023309 (rank : 40)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BU11, Q80UI2, Q99PN9, Q9CS16	Gene names
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

IRX4_MOUSE
NC score	0.023125 (rank : 41)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	286	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QY61	Gene names	Irx4, Irxa3
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3).

CCD96_MOUSE
NC score	0.022615 (rank : 42)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	704	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

SMCA4_HUMAN
NC score	0.022361 (rank : 43)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	597	Shared Neighborhood Hits	9
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

K0555_HUMAN
NC score	0.022184 (rank : 44)	θ value	0.125558 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	880	Shared Neighborhood Hits	11
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

CCDC7_HUMAN
NC score	0.022133 (rank : 45)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	253	Shared Neighborhood Hits	5
SwissProt Accessions	Q96M83, Q8IVQ0, Q8NEQ0	Gene names	CCDC7
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 7.

ITSN2_HUMAN
NC score	0.020473 (rank : 46)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	1173	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

LDB3_HUMAN
NC score	0.018824 (rank : 47)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	497	Shared Neighborhood Hits	11
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

SWP70_MOUSE
NC score	0.017765 (rank : 48)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	1097	Shared Neighborhood Hits	12
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CEP68_MOUSE
NC score	0.014816 (rank : 49)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0D9, Q3US49, Q5SW85, Q8R2V0	Gene names	Cep68
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

RGS3_HUMAN
NC score	0.014554 (rank : 50)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	1375	Shared Neighborhood Hits	20
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CE290_HUMAN
NC score	0.014044 (rank : 51)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	1553	Shared Neighborhood Hits	18
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

RFIP3_HUMAN
NC score	0.013471 (rank : 52)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	1055	Shared Neighborhood Hits	16
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

LDB3_MOUSE
NC score	0.012600 (rank : 53)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	510	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

SPTN2_HUMAN
NC score	0.011889 (rank : 54)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	535	Shared Neighborhood Hits	10
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SYNE1_HUMAN
NC score	0.011434 (rank : 55)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	1484	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

GNDS_HUMAN
NC score	0.010598 (rank : 56)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	201	Shared Neighborhood Hits	4
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

CRBB1_HUMAN
NC score	0.009532 (rank : 57)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P53674	Gene names	CRYBB1
Domain Architecture
Description	Beta crystallin B1.

LRC8C_MOUSE
NC score	0.007860 (rank : 58)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R502, Q3TEP9, Q8C296, Q8R0N7, Q8R3G5	Gene names	Lrrc8c, Ad158
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 8C (Protein AD158).

ABL1_MOUSE
NC score	0.006093 (rank : 59)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	1178	Shared Neighborhood Hits	13
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

MRP2_MOUSE
NC score	0.005946 (rank : 60)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

SORC3_HUMAN
NC score	0.005899 (rank : 61)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPU3, Q5VXF9, Q9NQJ2	Gene names	SORCS3, KIAA1059
Domain Architecture
Description	VPS10 domain-containing receptor SorCS3 precursor.

COBA2_HUMAN
NC score	0.005837 (rank : 62)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	408	Shared Neighborhood Hits	3
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

PEX1_HUMAN
NC score	0.005526 (rank : 63)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	O43933, Q96S71, Q96S72, Q96S73, Q99994	Gene names	PEX1
Domain Architecture
Description	Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1).

SREC2_MOUSE
NC score	0.004932 (rank : 64)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	605	Shared Neighborhood Hits	4
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CD248_MOUSE
NC score	0.004769 (rank : 65)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	578	Shared Neighborhood Hits	11
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

KLC4_MOUSE
NC score	0.003923 (rank : 66)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	336	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

SPB6_HUMAN
NC score	0.001366 (rank : 67)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	P35237, Q96J44	Gene names	SERPINB6, PI6, PTI
Domain Architecture
Description	Serpin B6 (Placental thrombin inhibitor) (Cytoplasmic antiproteinase) (CAP) (Protease inhibitor 6) (PI-6).

PASK_HUMAN
NC score	0.000872 (rank : 68)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	857	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RG2, Q86XH6, Q99763, Q9UFR7	Gene names	PASK, KIAA0135
Domain Architecture
Description	PAS domain-containing serine/threonine-protein kinase (EC 2.7.11.1) (PAS-kinase) (PASKIN) (hPASK).