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Network neighborhood for query Sequence : TOM1_MOUSE

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TOM1_MOUSE
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TOM1_HUMAN
θ value	0 (rank : 1)	NC score	0.991669 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

TOM1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

TM1L1_HUMAN
θ value	3.71096e-62 (rank : 3)	NC score	0.913547 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	52	Shared Neighborhood Hits	18
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

TM1L1_MOUSE
θ value	2.03627e-60 (rank : 4)	NC score	0.910587 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

GGA3_HUMAN
θ value	1.24688e-25 (rank : 5)	NC score	0.720624 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	127	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA1_MOUSE
θ value	7.56453e-23 (rank : 6)	NC score	0.690628 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA3_MOUSE
θ value	7.56453e-23 (rank : 7)	NC score	0.699684 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	148	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

STAM1_HUMAN
θ value	2.20094e-22 (rank : 8)	NC score	0.532609 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM1_MOUSE
θ value	2.87452e-22 (rank : 9)	NC score	0.525793 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	273	Shared Neighborhood Hits	17
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

GGA1_HUMAN
θ value	7.0802e-21 (rank : 10)	NC score	0.687548 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

STAM2_HUMAN
θ value	2.69047e-20 (rank : 11)	NC score	0.541267 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	17
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM2_MOUSE
θ value	2.69047e-20 (rank : 12)	NC score	0.526130 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

HGS_HUMAN
θ value	8.10077e-17 (rank : 13)	NC score	0.485882 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	517	Shared Neighborhood Hits	18
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
θ value	8.10077e-17 (rank : 14)	NC score	0.483619 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	589	Shared Neighborhood Hits	20
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

GGA2_HUMAN
θ value	3.07829e-16 (rank : 15)	NC score	0.666493 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	114	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA2_MOUSE
θ value	1.68911e-14 (rank : 16)	NC score	0.662699 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

CKAP4_HUMAN
θ value	0.0330416 (rank : 17)	NC score	0.031773 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	592	Shared Neighborhood Hits	11
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

DESP_HUMAN
θ value	0.279714 (rank : 18)	NC score	0.015912 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	1470	Shared Neighborhood Hits	15
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

CMGA_HUMAN
θ value	0.62314 (rank : 19)	NC score	0.031678 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	238	Shared Neighborhood Hits	2
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

GOGA1_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.021075 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	1222	Shared Neighborhood Hits	17
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

TCOF_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.032017 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	471	Shared Neighborhood Hits	5
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ESAM_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.018916 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	251	Shared Neighborhood Hits	2
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

SSNA1_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.053894 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	182	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJ94	Gene names	Ssna1
Domain Architecture	No domain graphic available
Description	Sjoegren syndrome nuclear autoantigen 1 homolog.

UBP34_MOUSE
θ value	1.38821 (rank : 24)	NC score	0.031005 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	189	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

RTN4_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.024419 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	341	Shared Neighborhood Hits	7
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

UBP34_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.029863 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

WRN_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.014711 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

RLA1_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.045606 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P05386	Gene names	RPLP1, RRP1
Domain Architecture
Description	60S acidic ribosomal protein P1.

SPTA2_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.030848 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	888	Shared Neighborhood Hits	14
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SSNA1_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.044605 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	175	Shared Neighborhood Hits	7
SwissProt Accessions	O43805, Q6FG70, Q9BVW8	Gene names	SSNA1, NA14
Domain Architecture
Description	Sjoegren syndrome nuclear autoantigen 1 (Nuclear autoantigen of 14 kDa).

NCOA6_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.025521 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	1202	Shared Neighborhood Hits	9
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PCBP4_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.014736 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

STRC_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.017577 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q7RTU9	Gene names	STRC
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

TPR_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.007461 (rank : 63)
Query Neighborhood Hits	53	Target Neighborhood Hits	1921	Shared Neighborhood Hits	15
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CHD4_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.005358 (rank : 67)
Query Neighborhood Hits	53	Target Neighborhood Hits	365	Shared Neighborhood Hits	4
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

GOG8A_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.016967 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	635	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

LRCH3_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.006204 (rank : 65)
Query Neighborhood Hits	53	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	Q96II8, Q96FP9, Q9NT52	Gene names	LRCH3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

LRP10_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.008912 (rank : 61)
Query Neighborhood Hits	53	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

RGL2_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.011231 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

SPTB2_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.015977 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	748	Shared Neighborhood Hits	12
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.015929 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	770	Shared Neighborhood Hits	13
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

CENPK_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.014598 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	273	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

GP1BA_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.005016 (rank : 68)
Query Neighborhood Hits	53	Target Neighborhood Hits	407	Shared Neighborhood Hits	4
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

RLA1_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.037791 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	P47955	Gene names	Rplp1
Domain Architecture
Description	60S acidic ribosomal protein P1.

IF4G1_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.007016 (rank : 64)
Query Neighborhood Hits	53	Target Neighborhood Hits	534	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PCBP4_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.012504 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

U171_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.018762 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q12980, Q4TT56, Q92469	Gene names	CGTHBA, C16orf35
Domain Architecture
Description	CGTHBA protein (-14 gene protein).

VDP_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.018788 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	645	Shared Neighborhood Hits	14
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

CHM4B_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.009773 (rank : 60)
Query Neighborhood Hits	53	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D8B3, Q3TXM7, Q91VM7, Q922P1	Gene names	Chmp4b
Domain Architecture
Description	Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b).

CLOCK_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.004661 (rank : 69)
Query Neighborhood Hits	53	Target Neighborhood Hits	127	Shared Neighborhood Hits	2
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

DYSF_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.005435 (rank : 66)
Query Neighborhood Hits	53	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

LZTS1_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.007957 (rank : 62)
Query Neighborhood Hits	53	Target Neighborhood Hits	532	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

ZFP91_HUMAN
θ value	8.99809 (rank : 53)	NC score	-0.002118 (rank : 70)
Query Neighborhood Hits	53	Target Neighborhood Hits	769	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JP5, Q86V47, Q96JP4, Q96QA3	Gene names	ZFP91
Domain Architecture	No domain graphic available
Description	Zinc finger protein 91 homolog (Zfp-91).

ABI1_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.051258 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	246	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI3_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.050083 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

AP1G1_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.102626 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.098897 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G2_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.088499 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP1G2_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.093879 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

DBNL_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.058651 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	244	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

DBNL_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.055329 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	306	Shared Neighborhood Hits	5
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

GRAP2_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.057735 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	304	Shared Neighborhood Hits	6
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.057603 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

NCF2_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.059043 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	229	Shared Neighborhood Hits	5
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

NCF4_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.053545 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SRC8_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.052694 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	269	Shared Neighborhood Hits	7
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

STAC3_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.064022 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.064994 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.054725 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.054514 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	268	Shared Neighborhood Hits	6
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

Hits sorted by NC score

TOM1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

TOM1_HUMAN
NC score	0.991669 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	O60784, Q5TIJ6	Gene names	TOM1
Domain Architecture
Description	Target of Myb protein 1.

TM1L1_HUMAN
NC score	0.913547 (rank : 3)	θ value	3.71096e-62 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	52	Shared Neighborhood Hits	18
SwissProt Accessions	O75674	Gene names	TOM1L1, SRCASM
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

TM1L1_MOUSE
NC score	0.910587 (rank : 4)	θ value	2.03627e-60 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	Q923U0, Q99KE0, Q9D6Y5	Gene names	Tom1l1, Srcasm
Domain Architecture
Description	TOM1-like 1 protein (Target of myb-like 1 protein) (Src-activating and signaling molecule protein).

GGA3_HUMAN
NC score	0.720624 (rank : 5)	θ value	1.24688e-25 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	127	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZ52, Q15017, Q6IS16, Q9UJY3	Gene names	GGA3, KIAA0154
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA3_MOUSE
NC score	0.699684 (rank : 6)	θ value	7.56453e-23 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	148	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BMI3, Q80U71	Gene names	Gga3, Kiaa0154
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3).

GGA1_MOUSE
NC score	0.690628 (rank : 7)	θ value	7.56453e-23 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA1_HUMAN
NC score	0.687548 (rank : 8)	θ value	7.0802e-21 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UJY5, Q5TG07, Q9BW94, Q9UG00, Q9UGW0, Q9UGW1	Gene names	GGA1
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GGA2_HUMAN
NC score	0.666493 (rank : 9)	θ value	3.07829e-16 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	114	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA2_MOUSE
NC score	0.662699 (rank : 10)	θ value	1.68911e-14 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	60	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

STAM2_HUMAN
NC score	0.541267 (rank : 11)	θ value	2.69047e-20 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	17
SwissProt Accessions	O75886, Q7LDQ0, Q9UF58	Gene names	STAM2
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2).

STAM1_HUMAN
NC score	0.532609 (rank : 12)	θ value	2.20094e-22 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q92783, Q8N6D9	Gene names	STAM, STAM1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

STAM2_MOUSE
NC score	0.526130 (rank : 13)	θ value	2.69047e-20 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

STAM1_MOUSE
NC score	0.525793 (rank : 14)	θ value	2.87452e-22 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	273	Shared Neighborhood Hits	17
SwissProt Accessions	P70297	Gene names	Stam, Stam1
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 1 (STAM-1).

HGS_HUMAN
NC score	0.485882 (rank : 15)	θ value	8.10077e-17 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	517	Shared Neighborhood Hits	18
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HGS_MOUSE
NC score	0.483619 (rank : 16)	θ value	8.10077e-17 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	589	Shared Neighborhood Hits	20
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

AP1G1_HUMAN
NC score	0.102626 (rank : 17)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	O43747, O75709, O75842, Q9UG09, Q9Y3U4	Gene names	AP1G1, ADTG, CLAPG1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G1_MOUSE
NC score	0.098897 (rank : 18)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	P22892	Gene names	Ap1g1, Adtg, Clapg1
Domain Architecture
Description	AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 gamma- 1 subunit) (Gamma-adaptin) (Adaptor protein complex AP-1 gamma-1 subunit) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain).

AP1G2_MOUSE
NC score	0.093879 (rank : 19)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	O88512	Gene names	Ap1g2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

AP1G2_HUMAN
NC score	0.088499 (rank : 20)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	O75843, O75504	Gene names	AP1G2
Domain Architecture
Description	AP-1 complex subunit gamma-2 (Adapter-related protein complex 1 gamma- 2 subunit) (Gamma2-adaptin) (Adaptor protein complex AP-1 gamma-2 subunit) (G2ad).

STAC3_MOUSE
NC score	0.064994 (rank : 21)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	53	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_HUMAN
NC score	0.064022 (rank : 22)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	53	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

NCF2_HUMAN
NC score	0.059043 (rank : 23)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	53	Target Neighborhood Hits	229	Shared Neighborhood Hits	5
SwissProt Accessions	P19878, Q2PP06, Q8NFC7, Q9BV51	Gene names	NCF2
Domain Architecture
Description	Neutrophil cytosol factor 2 (NCF-2) (Neutrophil NADPH oxidase factor 2) (67 kDa neutrophil oxidase factor) (p67-phox) (NOXA2).

DBNL_HUMAN
NC score	0.058651 (rank : 24)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	53	Target Neighborhood Hits	244	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UJU6, P84070, Q6IAI8, Q96F30, Q96K74, Q9HBN8, Q9NR72	Gene names	DBNL, CMAP, SH3P7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F) (Cervical SH3P7) (HPK1-interacting protein of 55 kDa) (HIP-55) (Cervical mucin-associated protein).

GRAP2_HUMAN
NC score	0.057735 (rank : 25)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	53	Target Neighborhood Hits	304	Shared Neighborhood Hits	6
SwissProt Accessions	O75791, O43726	Gene names	GRAP2, GADS, GRB2L, GRID
Domain Architecture
Description	GRB2-related adapter protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (Grf40 adapter protein) (Grf-40) (GRB-2-like protein) (GRB2L) (GRBX) (P38) (Hematopoietic cell-associated adapter protein GrpL) (Adapter protein GRID) (SH3-SH2-SH3 adapter Mona).

GRAP2_MOUSE
NC score	0.057603 (rank : 26)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	53	Target Neighborhood Hits	297	Shared Neighborhood Hits	5
SwissProt Accessions	O89100	Gene names	Grap2, Gads, Grb2l, Grid, Mona
Domain Architecture
Description	GRB2-related adaptor protein 2 (GADS protein) (Growth factor receptor- binding protein) (GRBLG) (GRB-2-like protein) (GRB2L) (Hematopoietic cell-associated adaptor protein GrpL) (GRB-2-related monocytic adapter protein) (Monocytic adapter) (MONA) (Adapter protein GRID).

DBNL_MOUSE
NC score	0.055329 (rank : 27)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	53	Target Neighborhood Hits	306	Shared Neighborhood Hits	5
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

STAC_HUMAN
NC score	0.054725 (rank : 28)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	53	Target Neighborhood Hits	276	Shared Neighborhood Hits	5
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
NC score	0.054514 (rank : 29)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	53	Target Neighborhood Hits	268	Shared Neighborhood Hits	6
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

SSNA1_MOUSE
NC score	0.053894 (rank : 30)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	182	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJ94	Gene names	Ssna1
Domain Architecture	No domain graphic available
Description	Sjoegren syndrome nuclear autoantigen 1 homolog.

NCF4_MOUSE
NC score	0.053545 (rank : 31)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	53	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	P97369	Gene names	Ncf4
Domain Architecture
Description	Neutrophil cytosol factor 4 (NCF-4) (Neutrophil NADPH oxidase factor 4) (p40-phox) (p40phox).

SRC8_HUMAN
NC score	0.052694 (rank : 32)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	53	Target Neighborhood Hits	269	Shared Neighborhood Hits	7
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

ABI1_MOUSE
NC score	0.051258 (rank : 33)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	246	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CBW3, Q60747, Q91ZM5, Q923I9, Q99KH4	Gene names	Abi1, Ssh3bp1
Domain Architecture	No domain graphic available
Description	Abl interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3 domain- binding protein 1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (e3B1) (Ablphilin-1).

ABI3_MOUSE
NC score	0.050083 (rank : 34)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BYZ1, Q6PE63, Q9D7S4	Gene names	Abi3, Nesh
Domain Architecture	No domain graphic available
Description	ABI gene family member 3 (New molecule including SH3) (Nesh).

RLA1_HUMAN
NC score	0.045606 (rank : 35)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P05386	Gene names	RPLP1, RRP1
Domain Architecture
Description	60S acidic ribosomal protein P1.

SSNA1_HUMAN
NC score	0.044605 (rank : 36)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	175	Shared Neighborhood Hits	7
SwissProt Accessions	O43805, Q6FG70, Q9BVW8	Gene names	SSNA1, NA14
Domain Architecture
Description	Sjoegren syndrome nuclear autoantigen 1 (Nuclear autoantigen of 14 kDa).

RLA1_MOUSE
NC score	0.037791 (rank : 37)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	P47955	Gene names	Rplp1
Domain Architecture
Description	60S acidic ribosomal protein P1.

TCOF_MOUSE
NC score	0.032017 (rank : 38)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	471	Shared Neighborhood Hits	5
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

CKAP4_HUMAN
NC score	0.031773 (rank : 39)	θ value	0.0330416 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	592	Shared Neighborhood Hits	11
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CMGA_HUMAN
NC score	0.031678 (rank : 40)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	238	Shared Neighborhood Hits	2
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

UBP34_MOUSE
NC score	0.031005 (rank : 41)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	189	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

SPTA2_HUMAN
NC score	0.030848 (rank : 42)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	888	Shared Neighborhood Hits	14
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

UBP34_HUMAN
NC score	0.029863 (rank : 43)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	210	Shared Neighborhood Hits	4
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

NCOA6_HUMAN
NC score	0.025521 (rank : 44)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	1202	Shared Neighborhood Hits	9
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RTN4_MOUSE
NC score	0.024419 (rank : 45)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	341	Shared Neighborhood Hits	7
SwissProt Accessions	Q99P72, Q5DTK9, Q7TNB7, Q80W95, Q8BGK7, Q8BGM9, Q8K290, Q8K3G8, Q9CTE3	Gene names	Rtn4, Kiaa0886, Nogo
Domain Architecture
Description	Reticulon-4 (Neurite outgrowth inhibitor) (Nogo protein).

GOGA1_HUMAN
NC score	0.021075 (rank : 46)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	1222	Shared Neighborhood Hits	17
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

ESAM_HUMAN
NC score	0.018916 (rank : 47)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	251	Shared Neighborhood Hits	2
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

VDP_HUMAN
NC score	0.018788 (rank : 48)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	645	Shared Neighborhood Hits	14
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

U171_HUMAN
NC score	0.018762 (rank : 49)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q12980, Q4TT56, Q92469	Gene names	CGTHBA, C16orf35
Domain Architecture
Description	CGTHBA protein (-14 gene protein).

STRC_HUMAN
NC score	0.017577 (rank : 50)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q7RTU9	Gene names	STRC
Domain Architecture	No domain graphic available
Description	Stereocilin precursor.

GOG8A_HUMAN
NC score	0.016967 (rank : 51)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	635	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

SPTB2_HUMAN
NC score	0.015977 (rank : 52)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	748	Shared Neighborhood Hits	12
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
NC score	0.015929 (rank : 53)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	770	Shared Neighborhood Hits	13
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

DESP_HUMAN
NC score	0.015912 (rank : 54)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	1470	Shared Neighborhood Hits	15
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

PCBP4_HUMAN
NC score	0.014736 (rank : 55)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	P57723, Q96AH7	Gene names	PCBP4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

WRN_MOUSE
NC score	0.014711 (rank : 56)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	295	Shared Neighborhood Hits	4
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

CENPK_HUMAN
NC score	0.014598 (rank : 57)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	273	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BS16, Q9H4L0	Gene names	CENPK, ICEN37
Domain Architecture	No domain graphic available
Description	Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33).

PCBP4_MOUSE
NC score	0.012504 (rank : 58)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P57724, Q91VR3	Gene names	Pcbp4
Domain Architecture
Description	Poly(rC)-binding protein 4 (Alpha-CP4).

RGL2_MOUSE
NC score	0.011231 (rank : 59)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

CHM4B_MOUSE
NC score	0.009773 (rank : 60)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D8B3, Q3TXM7, Q91VM7, Q922P1	Gene names	Chmp4b
Domain Architecture
Description	Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b).

LRP10_MOUSE
NC score	0.008912 (rank : 61)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LZTS1_HUMAN
NC score	0.007957 (rank : 62)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	532	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

TPR_HUMAN
NC score	0.007461 (rank : 63)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	1921	Shared Neighborhood Hits	15
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

IF4G1_MOUSE
NC score	0.007016 (rank : 64)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	534	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

LRCH3_HUMAN
NC score	0.006204 (rank : 65)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	270	Shared Neighborhood Hits	3
SwissProt Accessions	Q96II8, Q96FP9, Q9NT52	Gene names	LRCH3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

DYSF_MOUSE
NC score	0.005435 (rank : 66)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

CHD4_HUMAN
NC score	0.005358 (rank : 67)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	365	Shared Neighborhood Hits	4
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

GP1BA_HUMAN
NC score	0.005016 (rank : 68)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	407	Shared Neighborhood Hits	4
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

CLOCK_HUMAN
NC score	0.004661 (rank : 69)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	127	Shared Neighborhood Hits	2
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

ZFP91_HUMAN
NC score	-0.002118 (rank : 70)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	769	Shared Neighborhood Hits	2
SwissProt Accessions	Q96JP5, Q86V47, Q96JP4, Q96QA3	Gene names	ZFP91
Domain Architecture	No domain graphic available
Description	Zinc finger protein 91 homolog (Zfp-91).