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Network neighborhood for query Sequence : DYSF_MOUSE

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DYSF_MOUSE
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DYSF_HUMAN
θ value	0 (rank : 1)	NC score	0.993568 (rank : 2)
Query Neighborhood Hits	162	Target Neighborhood Hits	170	Shared Neighborhood Hits	133
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DYSF_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	162	Target Neighborhood Hits	162	Shared Neighborhood Hits	162
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

MYOF_HUMAN
θ value	0 (rank : 3)	NC score	0.979873 (rank : 3)
Query Neighborhood Hits	162	Target Neighborhood Hits	147	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

OTOF_HUMAN
θ value	0 (rank : 4)	NC score	0.912931 (rank : 4)
Query Neighborhood Hits	162	Target Neighborhood Hits	168	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
θ value	0 (rank : 5)	NC score	0.910911 (rank : 5)
Query Neighborhood Hits	162	Target Neighborhood Hits	196	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

RASL1_HUMAN
θ value	1.25267e-09 (rank : 6)	NC score	0.422919 (rank : 13)
Query Neighborhood Hits	162	Target Neighborhood Hits	142	Shared Neighborhood Hits	103
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

RASL1_MOUSE
θ value	5.26297e-08 (rank : 7)	NC score	0.405712 (rank : 30)
Query Neighborhood Hits	162	Target Neighborhood Hits	148	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

PCLO_HUMAN
θ value	7.59969e-07 (rank : 8)	NC score	0.310725 (rank : 51)
Query Neighborhood Hits	162	Target Neighborhood Hits	2046	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SYT10_MOUSE
θ value	7.59969e-07 (rank : 9)	NC score	0.421659 (rank : 14)
Query Neighborhood Hits	162	Target Neighborhood Hits	133	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

DOC2A_MOUSE
θ value	1.69304e-06 (rank : 10)	NC score	0.431373 (rank : 6)
Query Neighborhood Hits	162	Target Neighborhood Hits	140	Shared Neighborhood Hits	118
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2B_HUMAN
θ value	3.77169e-06 (rank : 11)	NC score	0.428566 (rank : 8)
Query Neighborhood Hits	162	Target Neighborhood Hits	150	Shared Neighborhood Hits	119
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT3_HUMAN
θ value	3.77169e-06 (rank : 12)	NC score	0.424453 (rank : 11)
Query Neighborhood Hits	162	Target Neighborhood Hits	145	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

KPCG_MOUSE
θ value	6.43352e-06 (rank : 13)	NC score	0.134858 (rank : 113)
Query Neighborhood Hits	162	Target Neighborhood Hits	1123	Shared Neighborhood Hits	116
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

RP3A_MOUSE
θ value	6.43352e-06 (rank : 14)	NC score	0.418211 (rank : 17)
Query Neighborhood Hits	162	Target Neighborhood Hits	510	Shared Neighborhood Hits	123
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT6_HUMAN
θ value	6.43352e-06 (rank : 15)	NC score	0.412245 (rank : 22)
Query Neighborhood Hits	162	Target Neighborhood Hits	138	Shared Neighborhood Hits	115
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_MOUSE
θ value	6.43352e-06 (rank : 16)	NC score	0.412643 (rank : 21)
Query Neighborhood Hits	162	Target Neighborhood Hits	132	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

DOC2A_HUMAN
θ value	8.40245e-06 (rank : 17)	NC score	0.428797 (rank : 7)
Query Neighborhood Hits	162	Target Neighborhood Hits	144	Shared Neighborhood Hits	117
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

SYT3_MOUSE
θ value	8.40245e-06 (rank : 18)	NC score	0.424701 (rank : 10)
Query Neighborhood Hits	162	Target Neighborhood Hits	147	Shared Neighborhood Hits	119
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

RASL2_HUMAN
θ value	1.09739e-05 (rank : 19)	NC score	0.409769 (rank : 26)
Query Neighborhood Hits	162	Target Neighborhood Hits	161	Shared Neighborhood Hits	114
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

DOC2B_MOUSE
θ value	1.43324e-05 (rank : 20)	NC score	0.426754 (rank : 9)
Query Neighborhood Hits	162	Target Neighborhood Hits	169	Shared Neighborhood Hits	118
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

KPCA_HUMAN
θ value	1.43324e-05 (rank : 21)	NC score	0.127363 (rank : 117)
Query Neighborhood Hits	162	Target Neighborhood Hits	1070	Shared Neighborhood Hits	119
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_MOUSE
θ value	1.43324e-05 (rank : 22)	NC score	0.125320 (rank : 120)
Query Neighborhood Hits	162	Target Neighborhood Hits	1067	Shared Neighborhood Hits	119
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCG_HUMAN
θ value	1.43324e-05 (rank : 23)	NC score	0.134568 (rank : 114)
Query Neighborhood Hits	162	Target Neighborhood Hits	1126	Shared Neighborhood Hits	117
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SYT10_HUMAN
θ value	1.43324e-05 (rank : 24)	NC score	0.416975 (rank : 18)
Query Neighborhood Hits	162	Target Neighborhood Hits	134	Shared Neighborhood Hits	116
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

PCLO_MOUSE
θ value	1.87187e-05 (rank : 25)	NC score	0.292964 (rank : 58)
Query Neighborhood Hits	162	Target Neighborhood Hits	2275	Shared Neighborhood Hits	130
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SYT9_MOUSE
θ value	1.87187e-05 (rank : 26)	NC score	0.409852 (rank : 25)
Query Neighborhood Hits	162	Target Neighborhood Hits	148	Shared Neighborhood Hits	117
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

FA62A_HUMAN
θ value	2.44474e-05 (rank : 27)	NC score	0.421318 (rank : 15)
Query Neighborhood Hits	162	Target Neighborhood Hits	168	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_MOUSE
θ value	2.44474e-05 (rank : 28)	NC score	0.424102 (rank : 12)
Query Neighborhood Hits	162	Target Neighborhood Hits	155	Shared Neighborhood Hits	118
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

ITSN2_HUMAN
θ value	2.44474e-05 (rank : 29)	NC score	0.172998 (rank : 97)
Query Neighborhood Hits	162	Target Neighborhood Hits	1173	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

SYT9_HUMAN
θ value	3.19293e-05 (rank : 30)	NC score	0.410029 (rank : 24)
Query Neighborhood Hits	162	Target Neighborhood Hits	144	Shared Neighborhood Hits	116
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

RP3A_HUMAN
θ value	4.1701e-05 (rank : 31)	NC score	0.419185 (rank : 16)
Query Neighborhood Hits	162	Target Neighborhood Hits	305	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

ITSN2_MOUSE
θ value	7.1131e-05 (rank : 32)	NC score	0.161424 (rank : 102)
Query Neighborhood Hits	162	Target Neighborhood Hits	1371	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

KPCB_HUMAN
θ value	7.1131e-05 (rank : 33)	NC score	0.125627 (rank : 119)
Query Neighborhood Hits	162	Target Neighborhood Hits	1121	Shared Neighborhood Hits	117
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

SYT1_HUMAN
θ value	9.29e-05 (rank : 34)	NC score	0.407811 (rank : 28)
Query Neighborhood Hits	162	Target Neighborhood Hits	150	Shared Neighborhood Hits	119
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	9.29e-05 (rank : 35)	NC score	0.407804 (rank : 29)
Query Neighborhood Hits	162	Target Neighborhood Hits	150	Shared Neighborhood Hits	119
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT5_HUMAN
θ value	0.000121331 (rank : 36)	NC score	0.413212 (rank : 20)
Query Neighborhood Hits	162	Target Neighborhood Hits	138	Shared Neighborhood Hits	119
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT5_MOUSE
θ value	0.000121331 (rank : 37)	NC score	0.413725 (rank : 19)
Query Neighborhood Hits	162	Target Neighborhood Hits	140	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYTL1_HUMAN
θ value	0.000121331 (rank : 38)	NC score	0.346325 (rank : 43)
Query Neighborhood Hits	162	Target Neighborhood Hits	227	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

KPCB_MOUSE
θ value	0.000158464 (rank : 39)	NC score	0.127198 (rank : 118)
Query Neighborhood Hits	162	Target Neighborhood Hits	1117	Shared Neighborhood Hits	117
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

SYT7_HUMAN
θ value	0.000158464 (rank : 40)	NC score	0.411416 (rank : 23)
Query Neighborhood Hits	162	Target Neighborhood Hits	137	Shared Neighborhood Hits	119
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

BAIP3_HUMAN
θ value	0.000270298 (rank : 41)	NC score	0.360251 (rank : 40)
Query Neighborhood Hits	162	Target Neighborhood Hits	108	Shared Neighborhood Hits	87
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

BAIP3_MOUSE
θ value	0.000461057 (rank : 42)	NC score	0.360502 (rank : 38)
Query Neighborhood Hits	162	Target Neighborhood Hits	112	Shared Neighborhood Hits	95
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

SYT7_MOUSE
θ value	0.000461057 (rank : 43)	NC score	0.408912 (rank : 27)
Query Neighborhood Hits	162	Target Neighborhood Hits	137	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

K0528_HUMAN
θ value	0.000786445 (rank : 44)	NC score	0.338108 (rank : 45)
Query Neighborhood Hits	162	Target Neighborhood Hits	96	Shared Neighborhood Hits	82
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	0.000786445 (rank : 45)	NC score	0.337700 (rank : 46)
Query Neighborhood Hits	162	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

SYT2_HUMAN
θ value	0.000786445 (rank : 46)	NC score	0.403822 (rank : 32)
Query Neighborhood Hits	162	Target Neighborhood Hits	142	Shared Neighborhood Hits	119
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_MOUSE
θ value	0.000786445 (rank : 47)	NC score	0.404815 (rank : 31)
Query Neighborhood Hits	162	Target Neighborhood Hits	143	Shared Neighborhood Hits	119
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT4_HUMAN
θ value	0.000786445 (rank : 48)	NC score	0.365717 (rank : 34)
Query Neighborhood Hits	162	Target Neighborhood Hits	121	Shared Neighborhood Hits	107
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

PA24B_MOUSE
θ value	0.00102713 (rank : 49)	NC score	0.225480 (rank : 69)
Query Neighborhood Hits	162	Target Neighborhood Hits	102	Shared Neighborhood Hits	80
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

SYTL1_MOUSE
θ value	0.00102713 (rank : 50)	NC score	0.323647 (rank : 50)
Query Neighborhood Hits	162	Target Neighborhood Hits	314	Shared Neighborhood Hits	89
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

UN13A_HUMAN
θ value	0.00175202 (rank : 51)	NC score	0.292534 (rank : 59)
Query Neighborhood Hits	162	Target Neighborhood Hits	285	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_MOUSE
θ value	0.00228821 (rank : 52)	NC score	0.290434 (rank : 60)
Query Neighborhood Hits	162	Target Neighborhood Hits	210	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13D_HUMAN
θ value	0.00228821 (rank : 53)	NC score	0.365045 (rank : 35)
Query Neighborhood Hits	162	Target Neighborhood Hits	117	Shared Neighborhood Hits	98
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

CPNE2_MOUSE
θ value	0.00390308 (rank : 54)	NC score	0.195774 (rank : 85)
Query Neighborhood Hits	162	Target Neighborhood Hits	82	Shared Neighborhood Hits	70
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE7_HUMAN
θ value	0.00390308 (rank : 55)	NC score	0.191987 (rank : 87)
Query Neighborhood Hits	162	Target Neighborhood Hits	92	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

SYTL2_HUMAN
θ value	0.00509761 (rank : 56)	NC score	0.359101 (rank : 41)
Query Neighborhood Hits	162	Target Neighborhood Hits	248	Shared Neighborhood Hits	98
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
θ value	0.00509761 (rank : 57)	NC score	0.358971 (rank : 42)
Query Neighborhood Hits	162	Target Neighborhood Hits	253	Shared Neighborhood Hits	104
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYT4_MOUSE
θ value	0.00665767 (rank : 58)	NC score	0.361804 (rank : 37)
Query Neighborhood Hits	162	Target Neighborhood Hits	123	Shared Neighborhood Hits	105
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYTL4_HUMAN
θ value	0.00665767 (rank : 59)	NC score	0.325828 (rank : 49)
Query Neighborhood Hits	162	Target Neighborhood Hits	138	Shared Neighborhood Hits	91
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

NEDD4_MOUSE
θ value	0.00869519 (rank : 60)	NC score	0.201202 (rank : 84)
Query Neighborhood Hits	162	Target Neighborhood Hits	212	Shared Neighborhood Hits	117
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

SYT11_MOUSE
θ value	0.00869519 (rank : 61)	NC score	0.361941 (rank : 36)
Query Neighborhood Hits	162	Target Neighborhood Hits	116	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_HUMAN
θ value	0.0113563 (rank : 62)	NC score	0.360326 (rank : 39)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYTL3_MOUSE
θ value	0.0113563 (rank : 63)	NC score	0.301168 (rank : 54)
Query Neighborhood Hits	162	Target Neighborhood Hits	110	Shared Neighborhood Hits	80
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYTL4_MOUSE
θ value	0.0113563 (rank : 64)	NC score	0.326036 (rank : 48)
Query Neighborhood Hits	162	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

UN13B_HUMAN
θ value	0.0113563 (rank : 65)	NC score	0.273112 (rank : 62)
Query Neighborhood Hits	162	Target Neighborhood Hits	217	Shared Neighborhood Hits	106
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

DOC2G_MOUSE
θ value	0.0148317 (rank : 66)	NC score	0.401752 (rank : 33)
Query Neighborhood Hits	162	Target Neighborhood Hits	125	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

CPNE6_HUMAN
θ value	0.0193708 (rank : 67)	NC score	0.179567 (rank : 94)
Query Neighborhood Hits	162	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

NED4L_HUMAN
θ value	0.0193708 (rank : 68)	NC score	0.209860 (rank : 74)
Query Neighborhood Hits	162	Target Neighborhood Hits	238	Shared Neighborhood Hits	118
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	0.0193708 (rank : 69)	NC score	0.205981 (rank : 77)
Query Neighborhood Hits	162	Target Neighborhood Hits	231	Shared Neighborhood Hits	116
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

PLCD1_HUMAN
θ value	0.0193708 (rank : 70)	NC score	0.130611 (rank : 116)
Query Neighborhood Hits	162	Target Neighborhood Hits	93	Shared Neighborhood Hits	56
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

SYTL5_HUMAN
θ value	0.0193708 (rank : 71)	NC score	0.334652 (rank : 47)
Query Neighborhood Hits	162	Target Neighborhood Hits	237	Shared Neighborhood Hits	111
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

CPNE6_MOUSE
θ value	0.0252991 (rank : 72)	NC score	0.175119 (rank : 96)
Query Neighborhood Hits	162	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

RFIP2_HUMAN
θ value	0.0252991 (rank : 73)	NC score	0.309215 (rank : 52)
Query Neighborhood Hits	162	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

NEDD4_HUMAN
θ value	0.0330416 (rank : 74)	NC score	0.202007 (rank : 83)
Query Neighborhood Hits	162	Target Neighborhood Hits	214	Shared Neighborhood Hits	117
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

SNPC4_MOUSE
θ value	0.0330416 (rank : 75)	NC score	0.042920 (rank : 137)
Query Neighborhood Hits	162	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

RFIP1_HUMAN
θ value	0.0431538 (rank : 76)	NC score	0.148606 (rank : 106)
Query Neighborhood Hits	162	Target Neighborhood Hits	236	Shared Neighborhood Hits	44
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

ASPP1_MOUSE
θ value	0.0736092 (rank : 77)	NC score	0.031900 (rank : 139)
Query Neighborhood Hits	162	Target Neighborhood Hits	1244	Shared Neighborhood Hits	17
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PA24D_MOUSE
θ value	0.0736092 (rank : 78)	NC score	0.256728 (rank : 64)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	93
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

P3C2B_HUMAN
θ value	0.0961366 (rank : 79)	NC score	0.191720 (rank : 88)
Query Neighborhood Hits	162	Target Neighborhood Hits	148	Shared Neighborhood Hits	78
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

PLCD1_MOUSE
θ value	0.0961366 (rank : 80)	NC score	0.102963 (rank : 126)
Query Neighborhood Hits	162	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

SYTL5_MOUSE
θ value	0.125558 (rank : 81)	NC score	0.338634 (rank : 44)
Query Neighborhood Hits	162	Target Neighborhood Hits	154	Shared Neighborhood Hits	107
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

CPNE8_HUMAN
θ value	0.163984 (rank : 82)	NC score	0.205832 (rank : 78)
Query Neighborhood Hits	162	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_MOUSE
θ value	0.163984 (rank : 83)	NC score	0.202879 (rank : 82)
Query Neighborhood Hits	162	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

ITSN1_HUMAN
θ value	0.163984 (rank : 84)	NC score	0.113246 (rank : 124)
Query Neighborhood Hits	162	Target Neighborhood Hits	1757	Shared Neighborhood Hits	101
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

ITSN1_MOUSE
θ value	0.163984 (rank : 85)	NC score	0.114369 (rank : 123)
Query Neighborhood Hits	162	Target Neighborhood Hits	1669	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

SYT15_MOUSE
θ value	0.163984 (rank : 86)	NC score	0.287885 (rank : 61)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

CPNE5_HUMAN
θ value	0.279714 (rank : 87)	NC score	0.202992 (rank : 81)
Query Neighborhood Hits	162	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
θ value	0.279714 (rank : 88)	NC score	0.203449 (rank : 80)
Query Neighborhood Hits	162	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

PRRT3_HUMAN
θ value	0.279714 (rank : 89)	NC score	0.029347 (rank : 140)
Query Neighborhood Hits	162	Target Neighborhood Hits	998	Shared Neighborhood Hits	20
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CPNE2_HUMAN
θ value	0.365318 (rank : 90)	NC score	0.186206 (rank : 90)
Query Neighborhood Hits	162	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

PA24A_MOUSE
θ value	0.365318 (rank : 91)	NC score	0.191520 (rank : 89)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	77
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24F_MOUSE
θ value	0.365318 (rank : 92)	NC score	0.134880 (rank : 112)
Query Neighborhood Hits	162	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

SYT13_HUMAN
θ value	0.365318 (rank : 93)	NC score	0.267427 (rank : 63)
Query Neighborhood Hits	162	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

PA24A_HUMAN
θ value	0.47712 (rank : 94)	NC score	0.185577 (rank : 91)
Query Neighborhood Hits	162	Target Neighborhood Hits	88	Shared Neighborhood Hits	78
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

RFIP1_MOUSE
θ value	0.47712 (rank : 95)	NC score	0.134312 (rank : 115)
Query Neighborhood Hits	162	Target Neighborhood Hits	152	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

RPGR1_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.033276 (rank : 138)
Query Neighborhood Hits	162	Target Neighborhood Hits	578	Shared Neighborhood Hits	16
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SYT15_HUMAN
θ value	0.47712 (rank : 97)	NC score	0.298134 (rank : 55)
Query Neighborhood Hits	162	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

CPNE1_MOUSE
θ value	0.62314 (rank : 98)	NC score	0.181462 (rank : 92)
Query Neighborhood Hits	162	Target Neighborhood Hits	83	Shared Neighborhood Hits	73
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE3_HUMAN
θ value	0.62314 (rank : 99)	NC score	0.206588 (rank : 76)
Query Neighborhood Hits	162	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
θ value	0.813845 (rank : 100)	NC score	0.208887 (rank : 75)
Query Neighborhood Hits	162	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

RIMS2_HUMAN
θ value	0.813845 (rank : 101)	NC score	0.232859 (rank : 66)
Query Neighborhood Hits	162	Target Neighborhood Hits	342	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	0.813845 (rank : 102)	NC score	0.230453 (rank : 67)
Query Neighborhood Hits	162	Target Neighborhood Hits	376	Shared Neighborhood Hits	101
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

PA24F_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.139271 (rank : 111)
Query Neighborhood Hits	162	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

RASA2_MOUSE
θ value	1.06291 (rank : 104)	NC score	0.225806 (rank : 68)
Query Neighborhood Hits	162	Target Neighborhood Hits	159	Shared Neighborhood Hits	83
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

PUNC_MOUSE
θ value	1.38821 (rank : 105)	NC score	0.005725 (rank : 169)
Query Neighborhood Hits	162	Target Neighborhood Hits	501	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

CT077_HUMAN
θ value	1.81305 (rank : 106)	NC score	0.025672 (rank : 144)
Query Neighborhood Hits	162	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQG5	Gene names	C20orf77
Domain Architecture
Description	Uncharacterized protein C20orf77.

CT077_MOUSE
θ value	1.81305 (rank : 107)	NC score	0.025996 (rank : 143)
Query Neighborhood Hits	162	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CSU0, Q3U8H1, Q3UGH1, Q3USX3, Q6GTJ6	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf77 homolog.

P3C2A_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.155613 (rank : 103)
Query Neighborhood Hits	162	Target Neighborhood Hits	188	Shared Neighborhood Hits	73
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

PTPRG_MOUSE
θ value	1.81305 (rank : 109)	NC score	0.005026 (rank : 171)
Query Neighborhood Hits	162	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

RGS3_HUMAN
θ value	1.81305 (rank : 110)	NC score	0.093661 (rank : 127)
Query Neighborhood Hits	162	Target Neighborhood Hits	1375	Shared Neighborhood Hits	83
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SYT13_MOUSE
θ value	1.81305 (rank : 111)	NC score	0.254934 (rank : 65)
Query Neighborhood Hits	162	Target Neighborhood Hits	69	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT8_MOUSE
θ value	1.81305 (rank : 112)	NC score	0.297054 (rank : 56)
Query Neighborhood Hits	162	Target Neighborhood Hits	94	Shared Neighborhood Hits	86
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

FYCO1_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.006572 (rank : 167)
Query Neighborhood Hits	162	Target Neighborhood Hits	1149	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

LRTM2_HUMAN
θ value	2.36792 (rank : 114)	NC score	0.003677 (rank : 175)
Query Neighborhood Hits	162	Target Neighborhood Hits	282	Shared Neighborhood Hits	3
SwissProt Accessions	O43300, Q7L770	Gene names	LRRTM2, KIAA0416, LRRN2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor (Leucine-rich repeat neuronal 2 protein).

P3C2A_MOUSE
θ value	2.36792 (rank : 115)	NC score	0.154165 (rank : 104)
Query Neighborhood Hits	162	Target Neighborhood Hits	181	Shared Neighborhood Hits	73
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

PLXB1_MOUSE
θ value	2.36792 (rank : 116)	NC score	0.006497 (rank : 168)
Query Neighborhood Hits	162	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

ARHGC_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.028768 (rank : 141)
Query Neighborhood Hits	162	Target Neighborhood Hits	344	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

CPNE1_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.163169 (rank : 100)
Query Neighborhood Hits	162	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

MIA2_MOUSE
θ value	3.0926 (rank : 119)	NC score	0.027901 (rank : 142)
Query Neighborhood Hits	162	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

PF21A_MOUSE
θ value	3.0926 (rank : 120)	NC score	0.008745 (rank : 159)
Query Neighborhood Hits	162	Target Neighborhood Hits	285	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

RASA3_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.195408 (rank : 86)
Query Neighborhood Hits	162	Target Neighborhood Hits	166	Shared Neighborhood Hits	80
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RIMS4_MOUSE
θ value	3.0926 (rank : 122)	NC score	0.180907 (rank : 93)
Query Neighborhood Hits	162	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

SCN8A_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.007133 (rank : 164)
Query Neighborhood Hits	162	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	3.0926 (rank : 124)	NC score	0.007077 (rank : 165)
Query Neighborhood Hits	162	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SRRM1_MOUSE
θ value	3.0926 (rank : 125)	NC score	0.020636 (rank : 147)
Query Neighborhood Hits	162	Target Neighborhood Hits	966	Shared Neighborhood Hits	18
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SSBP4_HUMAN
θ value	3.0926 (rank : 126)	NC score	0.012446 (rank : 153)
Query Neighborhood Hits	162	Target Neighborhood Hits	753	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SYT12_MOUSE
θ value	3.0926 (rank : 127)	NC score	0.303031 (rank : 53)
Query Neighborhood Hits	162	Target Neighborhood Hits	102	Shared Neighborhood Hits	90
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

AMPH_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.018679 (rank : 148)
Query Neighborhood Hits	162	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

HPS3_HUMAN
θ value	4.03905 (rank : 129)	NC score	0.023603 (rank : 145)
Query Neighborhood Hits	162	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q969F9, Q8WTV6, Q96AP1, Q96MR3, Q9H608	Gene names	HPS3
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein.

KRHB1_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.003925 (rank : 173)
Query Neighborhood Hits	162	Target Neighborhood Hits	461	Shared Neighborhood Hits	6
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

KRHB3_HUMAN
θ value	4.03905 (rank : 131)	NC score	0.004037 (rank : 172)
Query Neighborhood Hits	162	Target Neighborhood Hits	438	Shared Neighborhood Hits	6
SwissProt Accessions	P78385, Q9NSB3	Gene names	KRTHB3
Domain Architecture
Description	Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3).

KRHB6_HUMAN
θ value	4.03905 (rank : 132)	NC score	0.003887 (rank : 174)
Query Neighborhood Hits	162	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

RASA3_MOUSE
θ value	4.03905 (rank : 133)	NC score	0.172626 (rank : 98)
Query Neighborhood Hits	162	Target Neighborhood Hits	144	Shared Neighborhood Hits	73
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RIMS4_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.179146 (rank : 95)
Query Neighborhood Hits	162	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

SMUF2_HUMAN
θ value	4.03905 (rank : 135)	NC score	0.091752 (rank : 128)
Query Neighborhood Hits	162	Target Neighborhood Hits	142	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

THSD1_MOUSE
θ value	4.03905 (rank : 136)	NC score	0.010238 (rank : 158)
Query Neighborhood Hits	162	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

DOT1L_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.017364 (rank : 149)
Query Neighborhood Hits	162	Target Neighborhood Hits	660	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

FLNB_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.011493 (rank : 154)
Query Neighborhood Hits	162	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

FLNB_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.011437 (rank : 155)
Query Neighborhood Hits	162	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

FYCO1_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.007621 (rank : 162)
Query Neighborhood Hits	162	Target Neighborhood Hits	1059	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

ITCH_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.046731 (rank : 136)
Query Neighborhood Hits	162	Target Neighborhood Hits	162	Shared Neighborhood Hits	29
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

LRTM2_MOUSE
θ value	5.27518 (rank : 142)	NC score	0.002672 (rank : 177)
Query Neighborhood Hits	162	Target Neighborhood Hits	279	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGA3, Q80U08	Gene names	Lrrtm2, Kiaa0416
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor.

MYBB_MOUSE
θ value	5.27518 (rank : 143)	NC score	0.016886 (rank : 150)
Query Neighborhood Hits	162	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P48972	Gene names	Mybl2, Bmyb
Domain Architecture
Description	Myb-related protein B (B-Myb).

NU214_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.013234 (rank : 152)
Query Neighborhood Hits	162	Target Neighborhood Hits	657	Shared Neighborhood Hits	14
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PA24B_HUMAN
θ value	5.27518 (rank : 145)	NC score	0.149989 (rank : 105)
Query Neighborhood Hits	162	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24E_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.162131 (rank : 101)
Query Neighborhood Hits	162	Target Neighborhood Hits	95	Shared Neighborhood Hits	80
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

SYT12_HUMAN
θ value	5.27518 (rank : 147)	NC score	0.294262 (rank : 57)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

DCC_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.003026 (rank : 176)
Query Neighborhood Hits	162	Target Neighborhood Hits	896	Shared Neighborhood Hits	14
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

ELK4_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.010474 (rank : 157)
Query Neighborhood Hits	162	Target Neighborhood Hits	184	Shared Neighborhood Hits	7
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

PA24D_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.204276 (rank : 79)
Query Neighborhood Hits	162	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PA24E_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.163540 (rank : 99)
Query Neighborhood Hits	162	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

RASA2_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.210202 (rank : 73)
Query Neighborhood Hits	162	Target Neighborhood Hits	157	Shared Neighborhood Hits	82
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RIMS1_HUMAN
θ value	6.88961 (rank : 153)	NC score	0.215630 (rank : 72)
Query Neighborhood Hits	162	Target Neighborhood Hits	437	Shared Neighborhood Hits	93
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

WWP1_MOUSE
θ value	6.88961 (rank : 154)	NC score	0.052556 (rank : 135)
Query Neighborhood Hits	162	Target Neighborhood Hits	138	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

BCR_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.020659 (rank : 146)
Query Neighborhood Hits	162	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

DCDC2_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.010727 (rank : 156)
Query Neighborhood Hits	162	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

DMD_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.008149 (rank : 160)
Query Neighborhood Hits	162	Target Neighborhood Hits	1111	Shared Neighborhood Hits	20
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DZIP3_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.007679 (rank : 161)
Query Neighborhood Hits	162	Target Neighborhood Hits	399	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.007445 (rank : 163)
Query Neighborhood Hits	162	Target Neighborhood Hits	414	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

KAD4_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.007014 (rank : 166)
Query Neighborhood Hits	162	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P27144	Gene names	AK3L1, AK3, AK4
Domain Architecture
Description	Adenylate kinase isoenzyme 4, mitochondrial (EC 2.7.4.3) (Adenylate kinase 3-like 1) (ATP-AMP transphosphorylase).

TOM1_MOUSE
θ value	8.99809 (rank : 161)	NC score	0.005435 (rank : 170)
Query Neighborhood Hits	162	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

ZP3_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.013998 (rank : 151)
Query Neighborhood Hits	162	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P21754, Q06633	Gene names	ZP3, ZP3A, ZPC
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Zona pellucida protein C) (Sperm receptor) (ZP3A/ZP3B).

CPNE4_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.146268 (rank : 107)
Query Neighborhood Hits	162	Target Neighborhood Hits	70	Shared Neighborhood Hits	62
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.145442 (rank : 108)
Query Neighborhood Hits	162	Target Neighborhood Hits	67	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

P3C2G_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.055399 (rank : 133)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

PERF_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.086127 (rank : 131)
Query Neighborhood Hits	162	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

PERF_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.106451 (rank : 125)
Query Neighborhood Hits	162	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

RASA1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.058396 (rank : 132)
Query Neighborhood Hits	162	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RIMS3_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.142478 (rank : 109)
Query Neighborhood Hits	162	Target Neighborhood Hits	66	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.140116 (rank : 110)
Query Neighborhood Hits	162	Target Neighborhood Hits	67	Shared Neighborhood Hits	62
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

SMUF1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.090722 (rank : 129)
Query Neighborhood Hits	162	Target Neighborhood Hits	135	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.089903 (rank : 130)
Query Neighborhood Hits	162	Target Neighborhood Hits	142	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SYT14_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.221785 (rank : 71)
Query Neighborhood Hits	162	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.224788 (rank : 70)
Query Neighborhood Hits	162	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

TAC2N_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.116594 (rank : 121)
Query Neighborhood Hits	162	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.114925 (rank : 122)
Query Neighborhood Hits	162	Target Neighborhood Hits	43	Shared Neighborhood Hits	34
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

WWC1_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.053721 (rank : 134)
Query Neighborhood Hits	162	Target Neighborhood Hits	290	Shared Neighborhood Hits	35
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

Hits sorted by NC score

DYSF_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	162	Target Neighborhood Hits	162	Shared Neighborhood Hits	162
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

DYSF_HUMAN
NC score	0.993568 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	162	Target Neighborhood Hits	170	Shared Neighborhood Hits	133
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

MYOF_HUMAN
NC score	0.979873 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	162	Target Neighborhood Hits	147	Shared Neighborhood Hits	107
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

OTOF_HUMAN
NC score	0.912931 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	162	Target Neighborhood Hits	168	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
NC score	0.910911 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	162	Target Neighborhood Hits	196	Shared Neighborhood Hits	97
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

DOC2A_MOUSE
NC score	0.431373 (rank : 6)	θ value	1.69304e-06 (rank : 10)
Query Neighborhood Hits	162	Target Neighborhood Hits	140	Shared Neighborhood Hits	118
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2A_HUMAN
NC score	0.428797 (rank : 7)	θ value	8.40245e-06 (rank : 17)
Query Neighborhood Hits	162	Target Neighborhood Hits	144	Shared Neighborhood Hits	117
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2B_HUMAN
NC score	0.428566 (rank : 8)	θ value	3.77169e-06 (rank : 11)
Query Neighborhood Hits	162	Target Neighborhood Hits	150	Shared Neighborhood Hits	119
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

DOC2B_MOUSE
NC score	0.426754 (rank : 9)	θ value	1.43324e-05 (rank : 20)
Query Neighborhood Hits	162	Target Neighborhood Hits	169	Shared Neighborhood Hits	118
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT3_MOUSE
NC score	0.424701 (rank : 10)	θ value	8.40245e-06 (rank : 18)
Query Neighborhood Hits	162	Target Neighborhood Hits	147	Shared Neighborhood Hits	119
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT3_HUMAN
NC score	0.424453 (rank : 11)	θ value	3.77169e-06 (rank : 12)
Query Neighborhood Hits	162	Target Neighborhood Hits	145	Shared Neighborhood Hits	118
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

FA62A_MOUSE
NC score	0.424102 (rank : 12)	θ value	2.44474e-05 (rank : 28)
Query Neighborhood Hits	162	Target Neighborhood Hits	155	Shared Neighborhood Hits	118
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

RASL1_HUMAN
NC score	0.422919 (rank : 13)	θ value	1.25267e-09 (rank : 6)
Query Neighborhood Hits	162	Target Neighborhood Hits	142	Shared Neighborhood Hits	103
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

SYT10_MOUSE
NC score	0.421659 (rank : 14)	θ value	7.59969e-07 (rank : 9)
Query Neighborhood Hits	162	Target Neighborhood Hits	133	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

FA62A_HUMAN
NC score	0.421318 (rank : 15)	θ value	2.44474e-05 (rank : 27)
Query Neighborhood Hits	162	Target Neighborhood Hits	168	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

RP3A_HUMAN
NC score	0.419185 (rank : 16)	θ value	4.1701e-05 (rank : 31)
Query Neighborhood Hits	162	Target Neighborhood Hits	305	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RP3A_MOUSE
NC score	0.418211 (rank : 17)	θ value	6.43352e-06 (rank : 14)
Query Neighborhood Hits	162	Target Neighborhood Hits	510	Shared Neighborhood Hits	123
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SYT10_HUMAN
NC score	0.416975 (rank : 18)	θ value	1.43324e-05 (rank : 24)
Query Neighborhood Hits	162	Target Neighborhood Hits	134	Shared Neighborhood Hits	116
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT5_MOUSE
NC score	0.413725 (rank : 19)	θ value	0.000121331 (rank : 37)
Query Neighborhood Hits	162	Target Neighborhood Hits	140	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT5_HUMAN
NC score	0.413212 (rank : 20)	θ value	0.000121331 (rank : 36)
Query Neighborhood Hits	162	Target Neighborhood Hits	138	Shared Neighborhood Hits	119
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT6_MOUSE
NC score	0.412643 (rank : 21)	θ value	6.43352e-06 (rank : 16)
Query Neighborhood Hits	162	Target Neighborhood Hits	132	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_HUMAN
NC score	0.412245 (rank : 22)	θ value	6.43352e-06 (rank : 15)
Query Neighborhood Hits	162	Target Neighborhood Hits	138	Shared Neighborhood Hits	115
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT7_HUMAN
NC score	0.411416 (rank : 23)	θ value	0.000158464 (rank : 40)
Query Neighborhood Hits	162	Target Neighborhood Hits	137	Shared Neighborhood Hits	119
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT9_HUMAN
NC score	0.410029 (rank : 24)	θ value	3.19293e-05 (rank : 30)
Query Neighborhood Hits	162	Target Neighborhood Hits	144	Shared Neighborhood Hits	116
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT9_MOUSE
NC score	0.409852 (rank : 25)	θ value	1.87187e-05 (rank : 26)
Query Neighborhood Hits	162	Target Neighborhood Hits	148	Shared Neighborhood Hits	117
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

RASL2_HUMAN
NC score	0.409769 (rank : 26)	θ value	1.09739e-05 (rank : 19)
Query Neighborhood Hits	162	Target Neighborhood Hits	161	Shared Neighborhood Hits	114
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

SYT7_MOUSE
NC score	0.408912 (rank : 27)	θ value	0.000461057 (rank : 43)
Query Neighborhood Hits	162	Target Neighborhood Hits	137	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT1_HUMAN
NC score	0.407811 (rank : 28)	θ value	9.29e-05 (rank : 34)
Query Neighborhood Hits	162	Target Neighborhood Hits	150	Shared Neighborhood Hits	119
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.407804 (rank : 29)	θ value	9.29e-05 (rank : 35)
Query Neighborhood Hits	162	Target Neighborhood Hits	150	Shared Neighborhood Hits	119
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

RASL1_MOUSE
NC score	0.405712 (rank : 30)	θ value	5.26297e-08 (rank : 7)
Query Neighborhood Hits	162	Target Neighborhood Hits	148	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

SYT2_MOUSE
NC score	0.404815 (rank : 31)	θ value	0.000786445 (rank : 47)
Query Neighborhood Hits	162	Target Neighborhood Hits	143	Shared Neighborhood Hits	119
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
NC score	0.403822 (rank : 32)	θ value	0.000786445 (rank : 46)
Query Neighborhood Hits	162	Target Neighborhood Hits	142	Shared Neighborhood Hits	119
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

DOC2G_MOUSE
NC score	0.401752 (rank : 33)	θ value	0.0148317 (rank : 66)
Query Neighborhood Hits	162	Target Neighborhood Hits	125	Shared Neighborhood Hits	106
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

SYT4_HUMAN
NC score	0.365717 (rank : 34)	θ value	0.000786445 (rank : 48)
Query Neighborhood Hits	162	Target Neighborhood Hits	121	Shared Neighborhood Hits	107
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

UN13D_HUMAN
NC score	0.365045 (rank : 35)	θ value	0.00228821 (rank : 53)
Query Neighborhood Hits	162	Target Neighborhood Hits	117	Shared Neighborhood Hits	98
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

SYT11_MOUSE
NC score	0.361941 (rank : 36)	θ value	0.00869519 (rank : 61)
Query Neighborhood Hits	162	Target Neighborhood Hits	116	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT4_MOUSE
NC score	0.361804 (rank : 37)	θ value	0.00665767 (rank : 58)
Query Neighborhood Hits	162	Target Neighborhood Hits	123	Shared Neighborhood Hits	105
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

BAIP3_MOUSE
NC score	0.360502 (rank : 38)	θ value	0.000461057 (rank : 42)
Query Neighborhood Hits	162	Target Neighborhood Hits	112	Shared Neighborhood Hits	95
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

SYT11_HUMAN
NC score	0.360326 (rank : 39)	θ value	0.0113563 (rank : 62)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	100
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

BAIP3_HUMAN
NC score	0.360251 (rank : 40)	θ value	0.000270298 (rank : 41)
Query Neighborhood Hits	162	Target Neighborhood Hits	108	Shared Neighborhood Hits	87
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

SYTL2_HUMAN
NC score	0.359101 (rank : 41)	θ value	0.00509761 (rank : 56)
Query Neighborhood Hits	162	Target Neighborhood Hits	248	Shared Neighborhood Hits	98
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
NC score	0.358971 (rank : 42)	θ value	0.00509761 (rank : 57)
Query Neighborhood Hits	162	Target Neighborhood Hits	253	Shared Neighborhood Hits	104
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL1_HUMAN
NC score	0.346325 (rank : 43)	θ value	0.000121331 (rank : 38)
Query Neighborhood Hits	162	Target Neighborhood Hits	227	Shared Neighborhood Hits	95
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL5_MOUSE
NC score	0.338634 (rank : 44)	θ value	0.125558 (rank : 81)
Query Neighborhood Hits	162	Target Neighborhood Hits	154	Shared Neighborhood Hits	107
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

K0528_HUMAN
NC score	0.338108 (rank : 45)	θ value	0.000786445 (rank : 44)
Query Neighborhood Hits	162	Target Neighborhood Hits	96	Shared Neighborhood Hits	82
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
NC score	0.337700 (rank : 46)	θ value	0.000786445 (rank : 45)
Query Neighborhood Hits	162	Target Neighborhood Hits	102	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

SYTL5_HUMAN
NC score	0.334652 (rank : 47)	θ value	0.0193708 (rank : 71)
Query Neighborhood Hits	162	Target Neighborhood Hits	237	Shared Neighborhood Hits	111
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYTL4_MOUSE
NC score	0.326036 (rank : 48)	θ value	0.0113563 (rank : 64)
Query Neighborhood Hits	162	Target Neighborhood Hits	137	Shared Neighborhood Hits	93
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_HUMAN
NC score	0.325828 (rank : 49)	θ value	0.00665767 (rank : 59)
Query Neighborhood Hits	162	Target Neighborhood Hits	138	Shared Neighborhood Hits	91
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL1_MOUSE
NC score	0.323647 (rank : 50)	θ value	0.00102713 (rank : 50)
Query Neighborhood Hits	162	Target Neighborhood Hits	314	Shared Neighborhood Hits	89
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

PCLO_HUMAN
NC score	0.310725 (rank : 51)	θ value	7.59969e-07 (rank : 8)
Query Neighborhood Hits	162	Target Neighborhood Hits	2046	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RFIP2_HUMAN
NC score	0.309215 (rank : 52)	θ value	0.0252991 (rank : 73)
Query Neighborhood Hits	162	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

SYT12_MOUSE
NC score	0.303031 (rank : 53)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	162	Target Neighborhood Hits	102	Shared Neighborhood Hits	90
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYTL3_MOUSE
NC score	0.301168 (rank : 54)	θ value	0.0113563 (rank : 63)
Query Neighborhood Hits	162	Target Neighborhood Hits	110	Shared Neighborhood Hits	80
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYT15_HUMAN
NC score	0.298134 (rank : 55)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	162	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT8_MOUSE
NC score	0.297054 (rank : 56)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	162	Target Neighborhood Hits	94	Shared Neighborhood Hits	86
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYT12_HUMAN
NC score	0.294262 (rank : 57)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

PCLO_MOUSE
NC score	0.292964 (rank : 58)	θ value	1.87187e-05 (rank : 25)
Query Neighborhood Hits	162	Target Neighborhood Hits	2275	Shared Neighborhood Hits	130
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

UN13A_HUMAN
NC score	0.292534 (rank : 59)	θ value	0.00175202 (rank : 51)
Query Neighborhood Hits	162	Target Neighborhood Hits	285	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_MOUSE
NC score	0.290434 (rank : 60)	θ value	0.00228821 (rank : 52)
Query Neighborhood Hits	162	Target Neighborhood Hits	210	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

SYT15_MOUSE
NC score	0.287885 (rank : 61)	θ value	0.163984 (rank : 86)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

UN13B_HUMAN
NC score	0.273112 (rank : 62)	θ value	0.0113563 (rank : 65)
Query Neighborhood Hits	162	Target Neighborhood Hits	217	Shared Neighborhood Hits	106
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

SYT13_HUMAN
NC score	0.267427 (rank : 63)	θ value	0.365318 (rank : 93)
Query Neighborhood Hits	162	Target Neighborhood Hits	76	Shared Neighborhood Hits	65
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

PA24D_MOUSE
NC score	0.256728 (rank : 64)	θ value	0.0736092 (rank : 78)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	93
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SYT13_MOUSE
NC score	0.254934 (rank : 65)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	162	Target Neighborhood Hits	69	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

RIMS2_HUMAN
NC score	0.232859 (rank : 66)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	162	Target Neighborhood Hits	342	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.230453 (rank : 67)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	162	Target Neighborhood Hits	376	Shared Neighborhood Hits	101
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RASA2_MOUSE
NC score	0.225806 (rank : 68)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	162	Target Neighborhood Hits	159	Shared Neighborhood Hits	83
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

PA24B_MOUSE
NC score	0.225480 (rank : 69)	θ value	0.00102713 (rank : 49)
Query Neighborhood Hits	162	Target Neighborhood Hits	102	Shared Neighborhood Hits	80
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

SYT14_MOUSE
NC score	0.224788 (rank : 70)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	162	Target Neighborhood Hits	82	Shared Neighborhood Hits	59
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_HUMAN
NC score	0.221785 (rank : 71)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	162	Target Neighborhood Hits	81	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

RIMS1_HUMAN
NC score	0.215630 (rank : 72)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	162	Target Neighborhood Hits	437	Shared Neighborhood Hits	93
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RASA2_HUMAN
NC score	0.210202 (rank : 73)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	162	Target Neighborhood Hits	157	Shared Neighborhood Hits	82
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

NED4L_HUMAN
NC score	0.209860 (rank : 74)	θ value	0.0193708 (rank : 68)
Query Neighborhood Hits	162	Target Neighborhood Hits	238	Shared Neighborhood Hits	118
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

CPNE3_MOUSE
NC score	0.208887 (rank : 75)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	162	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_HUMAN
NC score	0.206588 (rank : 76)	θ value	0.62314 (rank : 99)
Query Neighborhood Hits	162	Target Neighborhood Hits	90	Shared Neighborhood Hits	76
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

NED4L_MOUSE
NC score	0.205981 (rank : 77)	θ value	0.0193708 (rank : 69)
Query Neighborhood Hits	162	Target Neighborhood Hits	231	Shared Neighborhood Hits	116
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

CPNE8_HUMAN
NC score	0.205832 (rank : 78)	θ value	0.163984 (rank : 82)
Query Neighborhood Hits	162	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

PA24D_HUMAN
NC score	0.204276 (rank : 79)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	162	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

CPNE5_MOUSE
NC score	0.203449 (rank : 80)	θ value	0.279714 (rank : 88)
Query Neighborhood Hits	162	Target Neighborhood Hits	86	Shared Neighborhood Hits	74
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_HUMAN
NC score	0.202992 (rank : 81)	θ value	0.279714 (rank : 87)
Query Neighborhood Hits	162	Target Neighborhood Hits	88	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE8_MOUSE
NC score	0.202879 (rank : 82)	θ value	0.163984 (rank : 83)
Query Neighborhood Hits	162	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

NEDD4_HUMAN
NC score	0.202007 (rank : 83)	θ value	0.0330416 (rank : 74)
Query Neighborhood Hits	162	Target Neighborhood Hits	214	Shared Neighborhood Hits	117
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NEDD4_MOUSE
NC score	0.201202 (rank : 84)	θ value	0.00869519 (rank : 60)
Query Neighborhood Hits	162	Target Neighborhood Hits	212	Shared Neighborhood Hits	117
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

CPNE2_MOUSE
NC score	0.195774 (rank : 85)	θ value	0.00390308 (rank : 54)
Query Neighborhood Hits	162	Target Neighborhood Hits	82	Shared Neighborhood Hits	70
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

RASA3_HUMAN
NC score	0.195408 (rank : 86)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	162	Target Neighborhood Hits	166	Shared Neighborhood Hits	80
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

CPNE7_HUMAN
NC score	0.191987 (rank : 87)	θ value	0.00390308 (rank : 55)
Query Neighborhood Hits	162	Target Neighborhood Hits	92	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

P3C2B_HUMAN
NC score	0.191720 (rank : 88)	θ value	0.0961366 (rank : 79)
Query Neighborhood Hits	162	Target Neighborhood Hits	148	Shared Neighborhood Hits	78
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

PA24A_MOUSE
NC score	0.191520 (rank : 89)	θ value	0.365318 (rank : 91)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	77
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

CPNE2_HUMAN
NC score	0.186206 (rank : 90)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	162	Target Neighborhood Hits	75	Shared Neighborhood Hits	67
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

PA24A_HUMAN
NC score	0.185577 (rank : 91)	θ value	0.47712 (rank : 94)
Query Neighborhood Hits	162	Target Neighborhood Hits	88	Shared Neighborhood Hits	78
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

CPNE1_MOUSE
NC score	0.181462 (rank : 92)	θ value	0.62314 (rank : 98)
Query Neighborhood Hits	162	Target Neighborhood Hits	83	Shared Neighborhood Hits	73
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

RIMS4_MOUSE
NC score	0.180907 (rank : 93)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	162	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

CPNE6_HUMAN
NC score	0.179567 (rank : 94)	θ value	0.0193708 (rank : 67)
Query Neighborhood Hits	162	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

RIMS4_HUMAN
NC score	0.179146 (rank : 95)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	162	Target Neighborhood Hits	76	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

CPNE6_MOUSE
NC score	0.175119 (rank : 96)	θ value	0.0252991 (rank : 72)
Query Neighborhood Hits	162	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

ITSN2_HUMAN
NC score	0.172998 (rank : 97)	θ value	2.44474e-05 (rank : 29)
Query Neighborhood Hits	162	Target Neighborhood Hits	1173	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

RASA3_MOUSE
NC score	0.172626 (rank : 98)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	162	Target Neighborhood Hits	144	Shared Neighborhood Hits	73
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

PA24E_HUMAN
NC score	0.163540 (rank : 99)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	162	Target Neighborhood Hits	89	Shared Neighborhood Hits	78
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

CPNE1_HUMAN
NC score	0.163169 (rank : 100)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	162	Target Neighborhood Hits	70	Shared Neighborhood Hits	65
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

PA24E_MOUSE
NC score	0.162131 (rank : 101)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	162	Target Neighborhood Hits	95	Shared Neighborhood Hits	80
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

ITSN2_MOUSE
NC score	0.161424 (rank : 102)	θ value	7.1131e-05 (rank : 32)
Query Neighborhood Hits	162	Target Neighborhood Hits	1371	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

P3C2A_HUMAN
NC score	0.155613 (rank : 103)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	162	Target Neighborhood Hits	188	Shared Neighborhood Hits	73
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
NC score	0.154165 (rank : 104)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	162	Target Neighborhood Hits	181	Shared Neighborhood Hits	73
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

PA24B_HUMAN
NC score	0.149989 (rank : 105)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	162	Target Neighborhood Hits	89	Shared Neighborhood Hits	73
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

RFIP1_HUMAN
NC score	0.148606 (rank : 106)	θ value	0.0431538 (rank : 76)
Query Neighborhood Hits	162	Target Neighborhood Hits	236	Shared Neighborhood Hits	44
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

CPNE4_HUMAN
NC score	0.146268 (rank : 107)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	162	Target Neighborhood Hits	70	Shared Neighborhood Hits	62
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
NC score	0.145442 (rank : 108)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	162	Target Neighborhood Hits	67	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

RIMS3_HUMAN
NC score	0.142478 (rank : 109)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	162	Target Neighborhood Hits	66	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
NC score	0.140116 (rank : 110)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	162	Target Neighborhood Hits	67	Shared Neighborhood Hits	62
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

PA24F_HUMAN
NC score	0.139271 (rank : 111)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	162	Target Neighborhood Hits	78	Shared Neighborhood Hits	67
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PA24F_MOUSE
NC score	0.134880 (rank : 112)	θ value	0.365318 (rank : 92)
Query Neighborhood Hits	162	Target Neighborhood Hits	93	Shared Neighborhood Hits	70
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

KPCG_MOUSE
NC score	0.134858 (rank : 113)	θ value	6.43352e-06 (rank : 13)
Query Neighborhood Hits	162	Target Neighborhood Hits	1123	Shared Neighborhood Hits	116
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_HUMAN
NC score	0.134568 (rank : 114)	θ value	1.43324e-05 (rank : 23)
Query Neighborhood Hits	162	Target Neighborhood Hits	1126	Shared Neighborhood Hits	117
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

RFIP1_MOUSE
NC score	0.134312 (rank : 115)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	162	Target Neighborhood Hits	152	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D620, Q3UBC2, Q8BN24	Gene names	Rab11fip1, Rcp
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

PLCD1_HUMAN
NC score	0.130611 (rank : 116)	θ value	0.0193708 (rank : 70)
Query Neighborhood Hits	162	Target Neighborhood Hits	93	Shared Neighborhood Hits	56
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

KPCA_HUMAN
NC score	0.127363 (rank : 117)	θ value	1.43324e-05 (rank : 21)
Query Neighborhood Hits	162	Target Neighborhood Hits	1070	Shared Neighborhood Hits	119
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_MOUSE
NC score	0.127198 (rank : 118)	θ value	0.000158464 (rank : 39)
Query Neighborhood Hits	162	Target Neighborhood Hits	1117	Shared Neighborhood Hits	117
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_HUMAN
NC score	0.125627 (rank : 119)	θ value	7.1131e-05 (rank : 33)
Query Neighborhood Hits	162	Target Neighborhood Hits	1121	Shared Neighborhood Hits	117
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_MOUSE
NC score	0.125320 (rank : 120)	θ value	1.43324e-05 (rank : 22)
Query Neighborhood Hits	162	Target Neighborhood Hits	1067	Shared Neighborhood Hits	119
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

TAC2N_HUMAN
NC score	0.116594 (rank : 121)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	162	Target Neighborhood Hits	47	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
NC score	0.114925 (rank : 122)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	162	Target Neighborhood Hits	43	Shared Neighborhood Hits	34
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

ITSN1_MOUSE
NC score	0.114369 (rank : 123)	θ value	0.163984 (rank : 85)
Query Neighborhood Hits	162	Target Neighborhood Hits	1669	Shared Neighborhood Hits	104
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.113246 (rank : 124)	θ value	0.163984 (rank : 84)
Query Neighborhood Hits	162	Target Neighborhood Hits	1757	Shared Neighborhood Hits	101
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

PERF_MOUSE
NC score	0.106451 (rank : 125)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	162	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

PLCD1_MOUSE
NC score	0.102963 (rank : 126)	θ value	0.0961366 (rank : 80)
Query Neighborhood Hits	162	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RGS3_HUMAN
NC score	0.093661 (rank : 127)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	162	Target Neighborhood Hits	1375	Shared Neighborhood Hits	83
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SMUF2_HUMAN
NC score	0.091752 (rank : 128)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	162	Target Neighborhood Hits	142	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SMUF1_HUMAN
NC score	0.090722 (rank : 129)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	162	Target Neighborhood Hits	135	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
NC score	0.089903 (rank : 130)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	162	Target Neighborhood Hits	142	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

PERF_HUMAN
NC score	0.086127 (rank : 131)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	162	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

RASA1_HUMAN
NC score	0.058396 (rank : 132)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	162	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

P3C2G_MOUSE
NC score	0.055399 (rank : 133)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	59
SwissProt Accessions	O70167, O70168	Gene names	Pik3c2g
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-gamma) (PtdIns-3-kinase C2 gamma) (PI3K-C2gamma).

WWC1_MOUSE
NC score	0.053721 (rank : 134)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	162	Target Neighborhood Hits	290	Shared Neighborhood Hits	35
SwissProt Accessions	Q5SXA9, Q571D0, Q8K1Y3, Q8VD17, Q922W3	Gene names	Wwc1, Kiaa0869
Domain Architecture	No domain graphic available
Description	WW domain-containing protein 1 (Kidney and brain protein) (KIBRA).

WWP1_MOUSE
NC score	0.052556 (rank : 135)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	162	Target Neighborhood Hits	138	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

ITCH_HUMAN
NC score	0.046731 (rank : 136)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	162	Target Neighborhood Hits	162	Shared Neighborhood Hits	29
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

SNPC4_MOUSE
NC score	0.042920 (rank : 137)	θ value	0.0330416 (rank : 75)
Query Neighborhood Hits	162	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

RPGR1_HUMAN
NC score	0.033276 (rank : 138)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	162	Target Neighborhood Hits	578	Shared Neighborhood Hits	16
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

ASPP1_MOUSE
NC score	0.031900 (rank : 139)	θ value	0.0736092 (rank : 77)
Query Neighborhood Hits	162	Target Neighborhood Hits	1244	Shared Neighborhood Hits	17
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

PRRT3_HUMAN
NC score	0.029347 (rank : 140)	θ value	0.279714 (rank : 89)
Query Neighborhood Hits	162	Target Neighborhood Hits	998	Shared Neighborhood Hits	20
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ARHGC_MOUSE
NC score	0.028768 (rank : 141)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	162	Target Neighborhood Hits	344	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R4H2, Q80U18	Gene names	Arhgef12, Kiaa0382, Larg
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

MIA2_MOUSE
NC score	0.027901 (rank : 142)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	162	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZV0	Gene names	Mia2
Domain Architecture	No domain graphic available
Description	Melanoma inhibitory activity protein 2 precursor.

CT077_MOUSE
NC score	0.025996 (rank : 143)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	162	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CSU0, Q3U8H1, Q3UGH1, Q3USX3, Q6GTJ6	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf77 homolog.

CT077_HUMAN
NC score	0.025672 (rank : 144)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	162	Target Neighborhood Hits	155	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQG5	Gene names	C20orf77
Domain Architecture
Description	Uncharacterized protein C20orf77.

HPS3_HUMAN
NC score	0.023603 (rank : 145)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	162	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q969F9, Q8WTV6, Q96AP1, Q96MR3, Q9H608	Gene names	HPS3
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 3 protein.

BCR_HUMAN
NC score	0.020659 (rank : 146)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	162	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

SRRM1_MOUSE
NC score	0.020636 (rank : 147)	θ value	3.0926 (rank : 125)
Query Neighborhood Hits	162	Target Neighborhood Hits	966	Shared Neighborhood Hits	18
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

AMPH_HUMAN
NC score	0.018679 (rank : 148)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	162	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

DOT1L_HUMAN
NC score	0.017364 (rank : 149)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	162	Target Neighborhood Hits	660	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

MYBB_MOUSE
NC score	0.016886 (rank : 150)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	162	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P48972	Gene names	Mybl2, Bmyb
Domain Architecture
Description	Myb-related protein B (B-Myb).

ZP3_HUMAN
NC score	0.013998 (rank : 151)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	162	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	P21754, Q06633	Gene names	ZP3, ZP3A, ZPC
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Zona pellucida protein C) (Sperm receptor) (ZP3A/ZP3B).

NU214_HUMAN
NC score	0.013234 (rank : 152)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	162	Target Neighborhood Hits	657	Shared Neighborhood Hits	14
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

SSBP4_HUMAN
NC score	0.012446 (rank : 153)	θ value	3.0926 (rank : 126)
Query Neighborhood Hits	162	Target Neighborhood Hits	753	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

FLNB_HUMAN
NC score	0.011493 (rank : 154)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	162	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

FLNB_MOUSE
NC score	0.011437 (rank : 155)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	162	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

DCDC2_HUMAN
NC score	0.010727 (rank : 156)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	162	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

ELK4_HUMAN
NC score	0.010474 (rank : 157)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	162	Target Neighborhood Hits	184	Shared Neighborhood Hits	7
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

THSD1_MOUSE
NC score	0.010238 (rank : 158)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	162	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

PF21A_MOUSE
NC score	0.008745 (rank : 159)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	162	Target Neighborhood Hits	285	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

DMD_MOUSE
NC score	0.008149 (rank : 160)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	162	Target Neighborhood Hits	1111	Shared Neighborhood Hits	20
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DZIP3_HUMAN
NC score	0.007679 (rank : 161)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	162	Target Neighborhood Hits	399	Shared Neighborhood Hits	8
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

FYCO1_MOUSE
NC score	0.007621 (rank : 162)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	162	Target Neighborhood Hits	1059	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

DZIP3_MOUSE
NC score	0.007445 (rank : 163)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	162	Target Neighborhood Hits	414	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

SCN8A_HUMAN
NC score	0.007133 (rank : 164)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	162	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
NC score	0.007077 (rank : 165)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	162	Target Neighborhood Hits	136	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

KAD4_HUMAN
NC score	0.007014 (rank : 166)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	162	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	P27144	Gene names	AK3L1, AK3, AK4
Domain Architecture
Description	Adenylate kinase isoenzyme 4, mitochondrial (EC 2.7.4.3) (Adenylate kinase 3-like 1) (ATP-AMP transphosphorylase).

FYCO1_HUMAN
NC score	0.006572 (rank : 167)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	162	Target Neighborhood Hits	1149	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

PLXB1_MOUSE
NC score	0.006497 (rank : 168)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	162	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

PUNC_MOUSE
NC score	0.005725 (rank : 169)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	162	Target Neighborhood Hits	501	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

TOM1_MOUSE
NC score	0.005435 (rank : 170)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	162	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	O88746, Q3V4C6, Q9D120	Gene names	Tom1
Domain Architecture
Description	Target of Myb protein 1.

PTPRG_MOUSE
NC score	0.005026 (rank : 171)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	162	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

KRHB3_HUMAN
NC score	0.004037 (rank : 172)	θ value	4.03905 (rank : 131)
Query Neighborhood Hits	162	Target Neighborhood Hits	438	Shared Neighborhood Hits	6
SwissProt Accessions	P78385, Q9NSB3	Gene names	KRTHB3
Domain Architecture
Description	Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3).

KRHB1_HUMAN
NC score	0.003925 (rank : 173)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	162	Target Neighborhood Hits	461	Shared Neighborhood Hits	6
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

KRHB6_HUMAN
NC score	0.003887 (rank : 174)	θ value	4.03905 (rank : 132)
Query Neighborhood Hits	162	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	O43790, P78387	Gene names	KRTHB6
Domain Architecture
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6).

LRTM2_HUMAN
NC score	0.003677 (rank : 175)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	162	Target Neighborhood Hits	282	Shared Neighborhood Hits	3
SwissProt Accessions	O43300, Q7L770	Gene names	LRRTM2, KIAA0416, LRRN2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor (Leucine-rich repeat neuronal 2 protein).

DCC_MOUSE
NC score	0.003026 (rank : 176)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	162	Target Neighborhood Hits	896	Shared Neighborhood Hits	14
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

LRTM2_MOUSE
NC score	0.002672 (rank : 177)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	162	Target Neighborhood Hits	279	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGA3, Q80U08	Gene names	Lrrtm2, Kiaa0416
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat transmembrane neuronal protein 2 precursor.