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Network neighborhood for query Sequence : CPNE3_HUMAN

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CPNE3_HUMAN
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CPNE1_HUMAN
θ value	0 (rank : 1)	NC score	0.990012 (rank : 5)
Query Neighborhood Hits	90	Target Neighborhood Hits	70	Shared Neighborhood Hits	66
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE1_MOUSE
θ value	0 (rank : 2)	NC score	0.991534 (rank : 3)
Query Neighborhood Hits	90	Target Neighborhood Hits	83	Shared Neighborhood Hits	73
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
θ value	0 (rank : 3)	NC score	0.990830 (rank : 4)
Query Neighborhood Hits	90	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE2_MOUSE
θ value	0 (rank : 4)	NC score	0.988968 (rank : 6)
Query Neighborhood Hits	90	Target Neighborhood Hits	82	Shared Neighborhood Hits	69
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	90
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
θ value	0 (rank : 6)	NC score	0.998031 (rank : 2)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE4_MOUSE
θ value	3.60074e-166 (rank : 7)	NC score	0.978294 (rank : 14)
Query Neighborhood Hits	90	Target Neighborhood Hits	67	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

CPNE4_HUMAN
θ value	3.04821e-165 (rank : 8)	NC score	0.978513 (rank : 13)
Query Neighborhood Hits	90	Target Neighborhood Hits	70	Shared Neighborhood Hits	61
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE6_MOUSE
θ value	9.80574e-164 (rank : 9)	NC score	0.979315 (rank : 12)
Query Neighborhood Hits	90	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_HUMAN
θ value	8.30107e-163 (rank : 10)	NC score	0.979879 (rank : 11)
Query Neighborhood Hits	90	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE8_MOUSE
θ value	3.61748e-150 (rank : 11)	NC score	0.983257 (rank : 9)
Query Neighborhood Hits	90	Target Neighborhood Hits	85	Shared Neighborhood Hits	72
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_HUMAN
θ value	6.17048e-150 (rank : 12)	NC score	0.983224 (rank : 10)
Query Neighborhood Hits	90	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE5_HUMAN
θ value	1.28662e-147 (rank : 13)	NC score	0.983815 (rank : 8)
Query Neighborhood Hits	90	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_MOUSE
θ value	3.7435e-147 (rank : 14)	NC score	0.983908 (rank : 7)
Query Neighborhood Hits	90	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE7_HUMAN
θ value	1.12976e-135 (rank : 15)	NC score	0.977879 (rank : 15)
Query Neighborhood Hits	90	Target Neighborhood Hits	92	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

SYT2_MOUSE
θ value	7.34386e-10 (rank : 16)	NC score	0.346277 (rank : 21)
Query Neighborhood Hits	90	Target Neighborhood Hits	143	Shared Neighborhood Hits	80
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT2_HUMAN
θ value	9.59137e-10 (rank : 17)	NC score	0.342339 (rank : 26)
Query Neighborhood Hits	90	Target Neighborhood Hits	142	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT5_HUMAN
θ value	6.21693e-09 (rank : 18)	NC score	0.329808 (rank : 31)
Query Neighborhood Hits	90	Target Neighborhood Hits	138	Shared Neighborhood Hits	80
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

SYT5_MOUSE
θ value	8.11959e-09 (rank : 19)	NC score	0.333441 (rank : 29)
Query Neighborhood Hits	90	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

SYT10_HUMAN
θ value	1.80886e-08 (rank : 20)	NC score	0.356581 (rank : 18)
Query Neighborhood Hits	90	Target Neighborhood Hits	134	Shared Neighborhood Hits	80
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT1_HUMAN
θ value	1.80886e-08 (rank : 21)	NC score	0.348647 (rank : 19)
Query Neighborhood Hits	90	Target Neighborhood Hits	150	Shared Neighborhood Hits	80
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
θ value	1.80886e-08 (rank : 22)	NC score	0.348627 (rank : 20)
Query Neighborhood Hits	90	Target Neighborhood Hits	150	Shared Neighborhood Hits	80
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT10_MOUSE
θ value	4.0297e-08 (rank : 23)	NC score	0.343310 (rank : 22)
Query Neighborhood Hits	90	Target Neighborhood Hits	133	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT9_MOUSE
θ value	5.26297e-08 (rank : 24)	NC score	0.368598 (rank : 16)
Query Neighborhood Hits	90	Target Neighborhood Hits	148	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYT9_HUMAN
θ value	1.17247e-07 (rank : 25)	NC score	0.359598 (rank : 17)
Query Neighborhood Hits	90	Target Neighborhood Hits	144	Shared Neighborhood Hits	80
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT3_HUMAN
θ value	1.99992e-07 (rank : 26)	NC score	0.342363 (rank : 25)
Query Neighborhood Hits	90	Target Neighborhood Hits	145	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT6_HUMAN
θ value	2.61198e-07 (rank : 27)	NC score	0.342488 (rank : 24)
Query Neighborhood Hits	90	Target Neighborhood Hits	138	Shared Neighborhood Hits	80
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

KPCG_MOUSE
θ value	5.81887e-07 (rank : 28)	NC score	0.125736 (rank : 90)
Query Neighborhood Hits	90	Target Neighborhood Hits	1123	Shared Neighborhood Hits	81
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

SYT3_MOUSE
θ value	5.81887e-07 (rank : 29)	NC score	0.340418 (rank : 27)
Query Neighborhood Hits	90	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT6_MOUSE
θ value	5.81887e-07 (rank : 30)	NC score	0.343003 (rank : 23)
Query Neighborhood Hits	90	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

KPCG_HUMAN
θ value	7.59969e-07 (rank : 31)	NC score	0.124276 (rank : 91)
Query Neighborhood Hits	90	Target Neighborhood Hits	1126	Shared Neighborhood Hits	81
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

DOC2B_MOUSE
θ value	1.29631e-06 (rank : 32)	NC score	0.338129 (rank : 28)
Query Neighborhood Hits	90	Target Neighborhood Hits	169	Shared Neighborhood Hits	80
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

KPCB_HUMAN
θ value	1.69304e-06 (rank : 33)	NC score	0.112858 (rank : 98)
Query Neighborhood Hits	90	Target Neighborhood Hits	1121	Shared Neighborhood Hits	81
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

DOC2B_HUMAN
θ value	8.40245e-06 (rank : 34)	NC score	0.330944 (rank : 30)
Query Neighborhood Hits	90	Target Neighborhood Hits	150	Shared Neighborhood Hits	81
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

KPCB_MOUSE
θ value	3.19293e-05 (rank : 35)	NC score	0.111038 (rank : 100)
Query Neighborhood Hits	90	Target Neighborhood Hits	1117	Shared Neighborhood Hits	81
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_MOUSE
θ value	4.1701e-05 (rank : 36)	NC score	0.111042 (rank : 99)
Query Neighborhood Hits	90	Target Neighborhood Hits	1067	Shared Neighborhood Hits	81
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

PCLO_MOUSE
θ value	9.29e-05 (rank : 37)	NC score	0.218635 (rank : 54)
Query Neighborhood Hits	90	Target Neighborhood Hits	2275	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

KPCA_HUMAN
θ value	0.00020696 (rank : 38)	NC score	0.109855 (rank : 101)
Query Neighborhood Hits	90	Target Neighborhood Hits	1070	Shared Neighborhood Hits	81
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

RP3A_MOUSE
θ value	0.00020696 (rank : 39)	NC score	0.308564 (rank : 35)
Query Neighborhood Hits	90	Target Neighborhood Hits	510	Shared Neighborhood Hits	79
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RP3A_HUMAN
θ value	0.000461057 (rank : 40)	NC score	0.305257 (rank : 37)
Query Neighborhood Hits	90	Target Neighborhood Hits	305	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

PCLO_HUMAN
θ value	0.00228821 (rank : 41)	NC score	0.225769 (rank : 52)
Query Neighborhood Hits	90	Target Neighborhood Hits	2046	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RASL1_HUMAN
θ value	0.00509761 (rank : 42)	NC score	0.317333 (rank : 32)
Query Neighborhood Hits	90	Target Neighborhood Hits	142	Shared Neighborhood Hits	78
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

DOC2A_HUMAN
θ value	0.00665767 (rank : 43)	NC score	0.301893 (rank : 38)
Query Neighborhood Hits	90	Target Neighborhood Hits	144	Shared Neighborhood Hits	79
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

PA24D_MOUSE
θ value	0.00665767 (rank : 44)	NC score	0.161318 (rank : 78)
Query Neighborhood Hits	90	Target Neighborhood Hits	100	Shared Neighborhood Hits	67
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

FA62A_MOUSE
θ value	0.00869519 (rank : 45)	NC score	0.267979 (rank : 41)
Query Neighborhood Hits	90	Target Neighborhood Hits	155	Shared Neighborhood Hits	78
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

RASL2_HUMAN
θ value	0.00869519 (rank : 46)	NC score	0.274738 (rank : 40)
Query Neighborhood Hits	90	Target Neighborhood Hits	161	Shared Neighborhood Hits	78
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

DOC2A_MOUSE
θ value	0.0113563 (rank : 47)	NC score	0.301335 (rank : 39)
Query Neighborhood Hits	90	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

MYOF_HUMAN
θ value	0.0148317 (rank : 48)	NC score	0.236700 (rank : 44)
Query Neighborhood Hits	90	Target Neighborhood Hits	147	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

SYT7_HUMAN
θ value	0.0148317 (rank : 49)	NC score	0.309181 (rank : 34)
Query Neighborhood Hits	90	Target Neighborhood Hits	137	Shared Neighborhood Hits	78
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

NED4L_HUMAN
θ value	0.0193708 (rank : 50)	NC score	0.182585 (rank : 66)
Query Neighborhood Hits	90	Target Neighborhood Hits	238	Shared Neighborhood Hits	79
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

NED4L_MOUSE
θ value	0.0193708 (rank : 51)	NC score	0.180661 (rank : 68)
Query Neighborhood Hits	90	Target Neighborhood Hits	231	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

OTOF_HUMAN
θ value	0.0193708 (rank : 52)	NC score	0.235104 (rank : 46)
Query Neighborhood Hits	90	Target Neighborhood Hits	168	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

RASL1_MOUSE
θ value	0.0252991 (rank : 53)	NC score	0.305281 (rank : 36)
Query Neighborhood Hits	90	Target Neighborhood Hits	148	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

UN13A_HUMAN
θ value	0.0252991 (rank : 54)	NC score	0.225835 (rank : 51)
Query Neighborhood Hits	90	Target Neighborhood Hits	285	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	0.0252991 (rank : 55)	NC score	0.237119 (rank : 43)
Query Neighborhood Hits	90	Target Neighborhood Hits	217	Shared Neighborhood Hits	78
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

SYT7_MOUSE
θ value	0.0330416 (rank : 56)	NC score	0.317299 (rank : 33)
Query Neighborhood Hits	90	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

UN13B_MOUSE
θ value	0.0431538 (rank : 57)	NC score	0.234351 (rank : 47)
Query Neighborhood Hits	90	Target Neighborhood Hits	210	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

DYSF_HUMAN
θ value	0.0563607 (rank : 58)	NC score	0.222838 (rank : 53)
Query Neighborhood Hits	90	Target Neighborhood Hits	170	Shared Neighborhood Hits	80
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

OTOF_MOUSE
θ value	0.0563607 (rank : 59)	NC score	0.232462 (rank : 48)
Query Neighborhood Hits	90	Target Neighborhood Hits	196	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

PA24E_MOUSE
θ value	0.0563607 (rank : 60)	NC score	0.113910 (rank : 95)
Query Neighborhood Hits	90	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

UVRAG_HUMAN
θ value	0.0961366 (rank : 61)	NC score	0.096228 (rank : 108)
Query Neighborhood Hits	90	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2Y5, O00392	Gene names	UVRAG
Domain Architecture	No domain graphic available
Description	UV radiation resistance-associated gene protein (p63).

PA24B_MOUSE
θ value	0.125558 (rank : 62)	NC score	0.137457 (rank : 85)
Query Neighborhood Hits	90	Target Neighborhood Hits	102	Shared Neighborhood Hits	67
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

DOC2G_MOUSE
θ value	0.163984 (rank : 63)	NC score	0.236648 (rank : 45)
Query Neighborhood Hits	90	Target Neighborhood Hits	125	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

FA62A_HUMAN
θ value	0.163984 (rank : 64)	NC score	0.240495 (rank : 42)
Query Neighborhood Hits	90	Target Neighborhood Hits	168	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

PA24D_HUMAN
θ value	0.21417 (rank : 65)	NC score	0.143574 (rank : 82)
Query Neighborhood Hits	90	Target Neighborhood Hits	97	Shared Neighborhood Hits	65
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

CAD13_MOUSE
θ value	0.47712 (rank : 66)	NC score	0.006232 (rank : 129)
Query Neighborhood Hits	90	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTR5	Gene names	Cdh13
Domain Architecture
Description	Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin).

ITSN2_HUMAN
θ value	0.47712 (rank : 67)	NC score	0.062498 (rank : 125)
Query Neighborhood Hits	90	Target Neighborhood Hits	1173	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

PA24E_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.113634 (rank : 96)
Query Neighborhood Hits	90	Target Neighborhood Hits	89	Shared Neighborhood Hits	62
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

DYSF_MOUSE
θ value	0.62314 (rank : 69)	NC score	0.206588 (rank : 57)
Query Neighborhood Hits	90	Target Neighborhood Hits	162	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

NEDD4_MOUSE
θ value	0.813845 (rank : 70)	NC score	0.140984 (rank : 84)
Query Neighborhood Hits	90	Target Neighborhood Hits	212	Shared Neighborhood Hits	78
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

NEDD4_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.142010 (rank : 83)
Query Neighborhood Hits	90	Target Neighborhood Hits	214	Shared Neighborhood Hits	77
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

PA24B_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.107032 (rank : 103)
Query Neighborhood Hits	90	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

SMUF1_HUMAN
θ value	1.81305 (rank : 73)	NC score	0.119486 (rank : 93)
Query Neighborhood Hits	90	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
θ value	1.81305 (rank : 74)	NC score	0.118756 (rank : 94)
Query Neighborhood Hits	90	Target Neighborhood Hits	142	Shared Neighborhood Hits	64
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

SMUF2_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.113251 (rank : 97)
Query Neighborhood Hits	90	Target Neighborhood Hits	142	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

SYTL5_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.199255 (rank : 62)
Query Neighborhood Hits	90	Target Neighborhood Hits	154	Shared Neighborhood Hits	71
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

HXD3_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.001898 (rank : 134)
Query Neighborhood Hits	90	Target Neighborhood Hits	433	Shared Neighborhood Hits	3
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

ITSN2_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.056788 (rank : 126)
Query Neighborhood Hits	90	Target Neighborhood Hits	1371	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

INP4B_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.063651 (rank : 124)
Query Neighborhood Hits	90	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P1Y8	Gene names	Inpp4b
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

TITIN_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.004917 (rank : 130)
Query Neighborhood Hits	90	Target Neighborhood Hits	2923	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

HXD3_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.001425 (rank : 135)
Query Neighborhood Hits	90	Target Neighborhood Hits	435	Shared Neighborhood Hits	3
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

UN13D_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.202732 (rank : 58)
Query Neighborhood Hits	90	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

BAIP3_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.181264 (rank : 67)
Query Neighborhood Hits	90	Target Neighborhood Hits	112	Shared Neighborhood Hits	68
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

GANC_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.009059 (rank : 128)
Query Neighborhood Hits	90	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TET4, Q52LQ4, Q8IWZ0, Q8IZM4, Q8IZM5	Gene names	GANC
Domain Architecture
Description	Neutral alpha-glucosidase C (EC 3.2.1.20).

PA24F_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.076572 (rank : 120)
Query Neighborhood Hits	90	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

UBP4_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.003173 (rank : 132)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

ANGL4_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.004124 (rank : 131)
Query Neighborhood Hits	90	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

CAD13_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.002709 (rank : 133)
Query Neighborhood Hits	90	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	P55290, Q8TBX3	Gene names	CDH13, CDHH
Domain Architecture
Description	Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin) (P105).

SYT8_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.214336 (rank : 55)
Query Neighborhood Hits	90	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYTL5_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.194495 (rank : 64)
Query Neighborhood Hits	90	Target Neighborhood Hits	237	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

BAIP3_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.157683 (rank : 80)
Query Neighborhood Hits	90	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

K0528_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.125903 (rank : 88)
Query Neighborhood Hits	90	Target Neighborhood Hits	96	Shared Neighborhood Hits	53
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.125813 (rank : 89)
Query Neighborhood Hits	90	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

P3C2A_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.081548 (rank : 119)
Query Neighborhood Hits	90	Target Neighborhood Hits	188	Shared Neighborhood Hits	45
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

P3C2A_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.082230 (rank : 118)
Query Neighborhood Hits	90	Target Neighborhood Hits	181	Shared Neighborhood Hits	45
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

P3C2B_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.097106 (rank : 107)
Query Neighborhood Hits	90	Target Neighborhood Hits	148	Shared Neighborhood Hits	47
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

PA24A_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.085902 (rank : 114)
Query Neighborhood Hits	90	Target Neighborhood Hits	88	Shared Neighborhood Hits	58
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24A_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.089449 (rank : 112)
Query Neighborhood Hits	90	Target Neighborhood Hits	100	Shared Neighborhood Hits	58
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

PA24F_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.084852 (rank : 117)
Query Neighborhood Hits	90	Target Neighborhood Hits	93	Shared Neighborhood Hits	63
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

PLCD1_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.085067 (rank : 116)
Query Neighborhood Hits	90	Target Neighborhood Hits	93	Shared Neighborhood Hits	46
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PLCD1_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.072708 (rank : 122)
Query Neighborhood Hits	90	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RASA2_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.097181 (rank : 106)
Query Neighborhood Hits	90	Target Neighborhood Hits	157	Shared Neighborhood Hits	54
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.102045 (rank : 105)
Query Neighborhood Hits	90	Target Neighborhood Hits	159	Shared Neighborhood Hits	55
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA3_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.103811 (rank : 104)
Query Neighborhood Hits	90	Target Neighborhood Hits	166	Shared Neighborhood Hits	51
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.085185 (rank : 115)
Query Neighborhood Hits	90	Target Neighborhood Hits	144	Shared Neighborhood Hits	51
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RFIP2_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.109208 (rank : 102)
Query Neighborhood Hits	90	Target Neighborhood Hits	97	Shared Neighborhood Hits	52
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

RGS3_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.053066 (rank : 127)
Query Neighborhood Hits	90	Target Neighborhood Hits	1375	Shared Neighborhood Hits	43
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

RIMS1_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.121999 (rank : 92)
Query Neighborhood Hits	90	Target Neighborhood Hits	437	Shared Neighborhood Hits	61
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

RIMS2_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.128177 (rank : 86)
Query Neighborhood Hits	90	Target Neighborhood Hits	342	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.126512 (rank : 87)
Query Neighborhood Hits	90	Target Neighborhood Hits	376	Shared Neighborhood Hits	65
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

RIMS3_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.076536 (rank : 121)
Query Neighborhood Hits	90	Target Neighborhood Hits	66	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS3_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.071545 (rank : 123)
Query Neighborhood Hits	90	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

RIMS4_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.092685 (rank : 110)
Query Neighborhood Hits	90	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.093256 (rank : 109)
Query Neighborhood Hits	90	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

SYT11_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.202348 (rank : 60)
Query Neighborhood Hits	90	Target Neighborhood Hits	113	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT11_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.208111 (rank : 56)
Query Neighborhood Hits	90	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT12_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.200647 (rank : 61)
Query Neighborhood Hits	90	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT12_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.202536 (rank : 59)
Query Neighborhood Hits	90	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT13_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.178204 (rank : 69)
Query Neighborhood Hits	90	Target Neighborhood Hits	76	Shared Neighborhood Hits	45
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT13_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.177209 (rank : 71)
Query Neighborhood Hits	90	Target Neighborhood Hits	69	Shared Neighborhood Hits	42
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYT14_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.160627 (rank : 79)
Query Neighborhood Hits	90	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT14_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.163276 (rank : 76)
Query Neighborhood Hits	90	Target Neighborhood Hits	82	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYT15_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.196239 (rank : 63)
Query Neighborhood Hits	90	Target Neighborhood Hits	112	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYT15_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.187690 (rank : 65)
Query Neighborhood Hits	90	Target Neighborhood Hits	100	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

SYT4_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.231313 (rank : 49)
Query Neighborhood Hits	90	Target Neighborhood Hits	121	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT4_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.229575 (rank : 50)
Query Neighborhood Hits	90	Target Neighborhood Hits	123	Shared Neighborhood Hits	68
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYTL1_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.169677 (rank : 73)
Query Neighborhood Hits	90	Target Neighborhood Hits	227	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL1_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.163065 (rank : 77)
Query Neighborhood Hits	90	Target Neighborhood Hits	314	Shared Neighborhood Hits	53
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SYTL2_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.169383 (rank : 75)
Query Neighborhood Hits	90	Target Neighborhood Hits	248	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL2_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.172657 (rank : 72)
Query Neighborhood Hits	90	Target Neighborhood Hits	253	Shared Neighborhood Hits	64
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL3_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.150114 (rank : 81)
Query Neighborhood Hits	90	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

SYTL4_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.169615 (rank : 74)
Query Neighborhood Hits	90	Target Neighborhood Hits	138	Shared Neighborhood Hits	52
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL4_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.178126 (rank : 70)
Query Neighborhood Hits	90	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

TAC2N_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.092331 (rank : 111)
Query Neighborhood Hits	90	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

TAC2N_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.088001 (rank : 113)
Query Neighborhood Hits	90	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

Hits sorted by NC score

CPNE3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	90
SwissProt Accessions	O75131, Q8IYA1	Gene names	CPNE3, CPN3, KIAA0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE3_MOUSE
NC score	0.998031 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BT60, Q5CZX9, Q5DU22	Gene names	Cpne3, Kiaa0636
Domain Architecture
Description	Copine-3 (Copine III).

CPNE1_MOUSE
NC score	0.991534 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	90	Target Neighborhood Hits	83	Shared Neighborhood Hits	73
SwissProt Accessions	Q8C166, Q925K4, Q925K5	Gene names	Cpne1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_HUMAN
NC score	0.990830 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	90	Target Neighborhood Hits	75	Shared Neighborhood Hits	68
SwissProt Accessions	Q96FN4, Q68D19, Q86XP9	Gene names	CPNE2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE1_HUMAN
NC score	0.990012 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	90	Target Neighborhood Hits	70	Shared Neighborhood Hits	66
SwissProt Accessions	Q99829, Q6IBL3, Q9H243, Q9NTZ7	Gene names	CPNE1, CPN1
Domain Architecture
Description	Copine-1 (Copine I).

CPNE2_MOUSE
NC score	0.988968 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	90	Target Neighborhood Hits	82	Shared Neighborhood Hits	69
SwissProt Accessions	P59108, Q8K1D7	Gene names	Cpne2
Domain Architecture
Description	Copine-2 (Copine II).

CPNE5_MOUSE
NC score	0.983908 (rank : 7)	θ value	3.7435e-147 (rank : 14)
Query Neighborhood Hits	90	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	Q8JZW4	Gene names	Cpne5
Domain Architecture
Description	Copine-5 (Copine V).

CPNE5_HUMAN
NC score	0.983815 (rank : 8)	θ value	1.28662e-147 (rank : 13)
Query Neighborhood Hits	90	Target Neighborhood Hits	88	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

CPNE8_MOUSE
NC score	0.983257 (rank : 9)	θ value	3.61748e-150 (rank : 11)
Query Neighborhood Hits	90	Target Neighborhood Hits	85	Shared Neighborhood Hits	72
SwissProt Accessions	Q9DC53, Q9CUZ8	Gene names	Cpne8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE8_HUMAN
NC score	0.983224 (rank : 10)	θ value	6.17048e-150 (rank : 12)
Query Neighborhood Hits	90	Target Neighborhood Hits	86	Shared Neighborhood Hits	72
SwissProt Accessions	Q86YQ8, Q2TB41	Gene names	CPNE8
Domain Architecture
Description	Copine-8 (Copine VIII).

CPNE6_HUMAN
NC score	0.979879 (rank : 11)	θ value	8.30107e-163 (rank : 10)
Query Neighborhood Hits	90	Target Neighborhood Hits	85	Shared Neighborhood Hits	67
SwissProt Accessions	O95741, Q53HA6, Q8WVG1	Gene names	CPNE6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE6_MOUSE
NC score	0.979315 (rank : 12)	θ value	9.80574e-164 (rank : 9)
Query Neighborhood Hits	90	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z140	Gene names	Cpne6
Domain Architecture
Description	Copine-6 (Copine VI) (Neuronal-copine) (N-copine).

CPNE4_HUMAN
NC score	0.978513 (rank : 13)	θ value	3.04821e-165 (rank : 8)
Query Neighborhood Hits	90	Target Neighborhood Hits	70	Shared Neighborhood Hits	61
SwissProt Accessions	Q96A23, Q8TEX1	Gene names	CPNE4
Domain Architecture
Description	Copine-4 (Copine IV) (Copine-8).

CPNE4_MOUSE
NC score	0.978294 (rank : 14)	θ value	3.60074e-166 (rank : 7)
Query Neighborhood Hits	90	Target Neighborhood Hits	67	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BLR2	Gene names	Cpne4
Domain Architecture	No domain graphic available
Description	Copine-4 (Copine IV).

CPNE7_HUMAN
NC score	0.977879 (rank : 15)	θ value	1.12976e-135 (rank : 15)
Query Neighborhood Hits	90	Target Neighborhood Hits	92	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

SYT9_MOUSE
NC score	0.368598 (rank : 16)	θ value	5.26297e-08 (rank : 24)
Query Neighborhood Hits	90	Target Neighborhood Hits	148	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0N9, Q8C280	Gene names	Syt9, Syt5
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX) (Synaptotagmin V).

SYT9_HUMAN
NC score	0.359598 (rank : 17)	θ value	1.17247e-07 (rank : 25)
Query Neighborhood Hits	90	Target Neighborhood Hits	144	Shared Neighborhood Hits	80
SwissProt Accessions	Q86SS6	Gene names	SYT9
Domain Architecture
Description	Synaptotagmin-9 (Synaptotagmin IX) (SytIX).

SYT10_HUMAN
NC score	0.356581 (rank : 18)	θ value	1.80886e-08 (rank : 20)
Query Neighborhood Hits	90	Target Neighborhood Hits	134	Shared Neighborhood Hits	80
SwissProt Accessions	Q6XYQ8	Gene names	SYT10
Domain Architecture	No domain graphic available
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT1_HUMAN
NC score	0.348647 (rank : 19)	θ value	1.80886e-08 (rank : 21)
Query Neighborhood Hits	90	Target Neighborhood Hits	150	Shared Neighborhood Hits	80
SwissProt Accessions	P21579	Gene names	SYT1, SYT
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT1_MOUSE
NC score	0.348627 (rank : 20)	θ value	1.80886e-08 (rank : 22)
Query Neighborhood Hits	90	Target Neighborhood Hits	150	Shared Neighborhood Hits	80
SwissProt Accessions	P46096	Gene names	Syt1
Domain Architecture
Description	Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65).

SYT2_MOUSE
NC score	0.346277 (rank : 21)	θ value	7.34386e-10 (rank : 16)
Query Neighborhood Hits	90	Target Neighborhood Hits	143	Shared Neighborhood Hits	80
SwissProt Accessions	P46097, Q8R0E1	Gene names	Syt2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT10_MOUSE
NC score	0.343310 (rank : 22)	θ value	4.0297e-08 (rank : 23)
Query Neighborhood Hits	90	Target Neighborhood Hits	133	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0N4	Gene names	Syt10
Domain Architecture
Description	Synaptotagmin-10 (Synaptotagmin X) (SytX).

SYT6_MOUSE
NC score	0.343003 (rank : 23)	θ value	5.81887e-07 (rank : 30)
Query Neighborhood Hits	90	Target Neighborhood Hits	132	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0N8	Gene names	Syt6
Domain Architecture
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT6_HUMAN
NC score	0.342488 (rank : 24)	θ value	2.61198e-07 (rank : 27)
Query Neighborhood Hits	90	Target Neighborhood Hits	138	Shared Neighborhood Hits	80
SwissProt Accessions	Q5T7P8	Gene names	SYT6
Domain Architecture	No domain graphic available
Description	Synaptotagmin-6 (Synaptotagmin VI) (SytVI).

SYT3_HUMAN
NC score	0.342363 (rank : 25)	θ value	1.99992e-07 (rank : 26)
Query Neighborhood Hits	90	Target Neighborhood Hits	145	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BQG1, Q8N5Z1, Q8N640	Gene names	SYT3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

SYT2_HUMAN
NC score	0.342339 (rank : 26)	θ value	9.59137e-10 (rank : 17)
Query Neighborhood Hits	90	Target Neighborhood Hits	142	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N9I0, Q496K5, Q8NBE5	Gene names	SYT2
Domain Architecture
Description	Synaptotagmin-2 (Synaptotagmin II) (SytII).

SYT3_MOUSE
NC score	0.340418 (rank : 27)	θ value	5.81887e-07 (rank : 29)
Query Neighborhood Hits	90	Target Neighborhood Hits	147	Shared Neighborhood Hits	77
SwissProt Accessions	O35681, P97791, Q80WV1	Gene names	Syt3
Domain Architecture
Description	Synaptotagmin-3 (Synaptotagmin III) (SytIII).

DOC2B_MOUSE
NC score	0.338129 (rank : 28)	θ value	1.29631e-06 (rank : 32)
Query Neighborhood Hits	90	Target Neighborhood Hits	169	Shared Neighborhood Hits	80
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT5_MOUSE
NC score	0.333441 (rank : 29)	θ value	8.11959e-09 (rank : 19)
Query Neighborhood Hits	90	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0N5	Gene names	Syt5, Syt9
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV) (Synaptotagmin IX).

DOC2B_HUMAN
NC score	0.330944 (rank : 30)	θ value	8.40245e-06 (rank : 34)
Query Neighborhood Hits	90	Target Neighborhood Hits	150	Shared Neighborhood Hits	81
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SYT5_HUMAN
NC score	0.329808 (rank : 31)	θ value	6.21693e-09 (rank : 18)
Query Neighborhood Hits	90	Target Neighborhood Hits	138	Shared Neighborhood Hits	80
SwissProt Accessions	O00445, Q86X72	Gene names	SYT5
Domain Architecture
Description	Synaptotagmin-5 (Synaptotagmin V) (SytV).

RASL1_HUMAN
NC score	0.317333 (rank : 32)	θ value	0.00509761 (rank : 42)
Query Neighborhood Hits	90	Target Neighborhood Hits	142	Shared Neighborhood Hits	78
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

SYT7_MOUSE
NC score	0.317299 (rank : 33)	θ value	0.0330416 (rank : 56)
Query Neighborhood Hits	90	Target Neighborhood Hits	137	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0N7	Gene names	Syt7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

SYT7_HUMAN
NC score	0.309181 (rank : 34)	θ value	0.0148317 (rank : 49)
Query Neighborhood Hits	90	Target Neighborhood Hits	137	Shared Neighborhood Hits	78
SwissProt Accessions	O43581	Gene names	SYT7
Domain Architecture
Description	Synaptotagmin-7 (Synaptotagmin VII) (SytVII).

RP3A_MOUSE
NC score	0.308564 (rank : 35)	θ value	0.00020696 (rank : 39)
Query Neighborhood Hits	90	Target Neighborhood Hits	510	Shared Neighborhood Hits	79
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RASL1_MOUSE
NC score	0.305281 (rank : 36)	θ value	0.0252991 (rank : 53)
Query Neighborhood Hits	90	Target Neighborhood Hits	148	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

RP3A_HUMAN
NC score	0.305257 (rank : 37)	θ value	0.000461057 (rank : 40)
Query Neighborhood Hits	90	Target Neighborhood Hits	305	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

DOC2A_HUMAN
NC score	0.301893 (rank : 38)	θ value	0.00665767 (rank : 43)
Query Neighborhood Hits	90	Target Neighborhood Hits	144	Shared Neighborhood Hits	79
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2A_MOUSE
NC score	0.301335 (rank : 39)	θ value	0.0113563 (rank : 47)
Query Neighborhood Hits	90	Target Neighborhood Hits	140	Shared Neighborhood Hits	80
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

RASL2_HUMAN
NC score	0.274738 (rank : 40)	θ value	0.00869519 (rank : 46)
Query Neighborhood Hits	90	Target Neighborhood Hits	161	Shared Neighborhood Hits	78
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

FA62A_MOUSE
NC score	0.267979 (rank : 41)	θ value	0.00869519 (rank : 45)
Query Neighborhood Hits	90	Target Neighborhood Hits	155	Shared Neighborhood Hits	78
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

FA62A_HUMAN
NC score	0.240495 (rank : 42)	θ value	0.163984 (rank : 64)
Query Neighborhood Hits	90	Target Neighborhood Hits	168	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

UN13B_HUMAN
NC score	0.237119 (rank : 43)	θ value	0.0252991 (rank : 55)
Query Neighborhood Hits	90	Target Neighborhood Hits	217	Shared Neighborhood Hits	78
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

MYOF_HUMAN
NC score	0.236700 (rank : 44)	θ value	0.0148317 (rank : 48)
Query Neighborhood Hits	90	Target Neighborhood Hits	147	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

DOC2G_MOUSE
NC score	0.236648 (rank : 45)	θ value	0.163984 (rank : 63)
Query Neighborhood Hits	90	Target Neighborhood Hits	125	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ESN1, Q6P8R8	Gene names	Doc2g
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein gamma (Doc2-gamma).

OTOF_HUMAN
NC score	0.235104 (rank : 46)	θ value	0.0193708 (rank : 52)
Query Neighborhood Hits	90	Target Neighborhood Hits	168	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

UN13B_MOUSE
NC score	0.234351 (rank : 47)	θ value	0.0431538 (rank : 57)
Query Neighborhood Hits	90	Target Neighborhood Hits	210	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

OTOF_MOUSE
NC score	0.232462 (rank : 48)	θ value	0.0563607 (rank : 59)
Query Neighborhood Hits	90	Target Neighborhood Hits	196	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

SYT4_HUMAN
NC score	0.231313 (rank : 49)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	90	Target Neighborhood Hits	121	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2B2, Q9P2K4	Gene names	SYT4, KIAA1342
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

SYT4_MOUSE
NC score	0.229575 (rank : 50)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	90	Target Neighborhood Hits	123	Shared Neighborhood Hits	68
SwissProt Accessions	P40749, Q3UFC1, Q8BGH3, Q8BRL6	Gene names	Syt4, Syt3
Domain Architecture
Description	Synaptotagmin-4 (Synaptotagmin IV) (SytIV).

UN13A_HUMAN
NC score	0.225835 (rank : 51)	θ value	0.0252991 (rank : 54)
Query Neighborhood Hits	90	Target Neighborhood Hits	285	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

PCLO_HUMAN
NC score	0.225769 (rank : 52)	θ value	0.00228821 (rank : 41)
Query Neighborhood Hits	90	Target Neighborhood Hits	2046	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

DYSF_HUMAN
NC score	0.222838 (rank : 53)	θ value	0.0563607 (rank : 58)
Query Neighborhood Hits	90	Target Neighborhood Hits	170	Shared Neighborhood Hits	80
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

PCLO_MOUSE
NC score	0.218635 (rank : 54)	θ value	9.29e-05 (rank : 37)
Query Neighborhood Hits	90	Target Neighborhood Hits	2275	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SYT8_MOUSE
NC score	0.214336 (rank : 55)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	90	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R0N6, Q64366, Q8C6E7	Gene names	Syt8
Domain Architecture
Description	Synaptotagmin-8 (Synaptotagmin VIII) (SytVIII).

SYT11_MOUSE
NC score	0.208111 (rank : 56)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	90	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9R0N3	Gene names	Syt11
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

DYSF_MOUSE
NC score	0.206588 (rank : 57)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	90	Target Neighborhood Hits	162	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

UN13D_HUMAN
NC score	0.202732 (rank : 58)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	90	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

SYT12_MOUSE
NC score	0.202536 (rank : 59)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	90	Target Neighborhood Hits	102	Shared Neighborhood Hits	56
SwissProt Accessions	Q920N7	Gene names	Syt12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYT11_HUMAN
NC score	0.202348 (rank : 60)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	90	Target Neighborhood Hits	113	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BT88, Q14998, Q68CT5, Q8IXU3, Q96SU2	Gene names	SYT11, KIAA0080
Domain Architecture
Description	Synaptotagmin-11 (Synaptotagmin XI) (SytXI).

SYT12_HUMAN
NC score	0.200647 (rank : 61)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	90	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q8IV01	Gene names	SYT12
Domain Architecture
Description	Synaptotagmin-12 (Synaptotagmin XII) (SytXII).

SYTL5_MOUSE
NC score	0.199255 (rank : 62)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	90	Target Neighborhood Hits	154	Shared Neighborhood Hits	71
SwissProt Accessions	Q80T23, Q812E5	Gene names	Sytl5, Slp5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYT15_HUMAN
NC score	0.196239 (rank : 63)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	90	Target Neighborhood Hits	112	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BQS2, Q7Z439, Q7Z440	Gene names	SYT15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV) (Chr10Syt).

SYTL5_HUMAN
NC score	0.194495 (rank : 64)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	90	Target Neighborhood Hits	237	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TDW5	Gene names	SYTL5, SLP5
Domain Architecture
Description	Synaptotagmin-like protein 5.

SYT15_MOUSE
NC score	0.187690 (rank : 65)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	90	Target Neighborhood Hits	100	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C6N3, Q7TN81, Q7TN82, Q8C999	Gene names	Syt15
Domain Architecture
Description	Synaptotagmin-15 (Synaptotagmin XV) (SytXV).

NED4L_HUMAN
NC score	0.182585 (rank : 66)	θ value	0.0193708 (rank : 50)
Query Neighborhood Hits	90	Target Neighborhood Hits	238	Shared Neighborhood Hits	79
SwissProt Accessions	Q96PU5, O43165, Q7Z5F1, Q7Z5F2, Q7Z5N3, Q8N5A7, Q8WUU9, Q9BW58, Q9H2W4, Q9NT88	Gene names	NEDD4L, KIAA0439, NEDL3
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

BAIP3_MOUSE
NC score	0.181264 (rank : 67)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	90	Target Neighborhood Hits	112	Shared Neighborhood Hits	68
SwissProt Accessions	Q80TT2, Q6RUT4	Gene names	Baiap3, Gm937, Kiaa0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

NED4L_MOUSE
NC score	0.180661 (rank : 68)	θ value	0.0193708 (rank : 51)
Query Neighborhood Hits	90	Target Neighborhood Hits	231	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CFI0, Q8BRT9, Q8BS42, Q99PK2	Gene names	Nedd4l, Kiaa0439, Nedd4b
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase NEDD4-like protein (EC 6.3.2.-) (Nedd4-2) (NEDD4.2).

SYT13_HUMAN
NC score	0.178204 (rank : 69)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	90	Target Neighborhood Hits	76	Shared Neighborhood Hits	45
SwissProt Accessions	Q7L8C5, Q9BQS3, Q9H041, Q9P2C0	Gene names	SYT13, KIAA1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYTL4_MOUSE
NC score	0.178126 (rank : 70)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	90	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYT13_MOUSE
NC score	0.177209 (rank : 71)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	90	Target Neighborhood Hits	69	Shared Neighborhood Hits	42
SwissProt Accessions	Q9EQT6, Q6ZPR2, Q8BRK6	Gene names	Syt13, Kiaa1427
Domain Architecture	No domain graphic available
Description	Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII).

SYTL2_MOUSE
NC score	0.172657 (rank : 72)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	90	Target Neighborhood Hits	253	Shared Neighborhood Hits	64
SwissProt Accessions	Q99N50, Q8BT37, Q99J89, Q99J90, Q99N51, Q99N52, Q99N55, Q99N56	Gene names	Sytl2, Slp2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYTL1_HUMAN
NC score	0.169677 (rank : 73)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	90	Target Neighborhood Hits	227	Shared Neighborhood Hits	56
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

SYTL4_HUMAN
NC score	0.169615 (rank : 74)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	90	Target Neighborhood Hits	138	Shared Neighborhood Hits	52
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

SYTL2_HUMAN
NC score	0.169383 (rank : 75)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	90	Target Neighborhood Hits	248	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

SYT14_MOUSE
NC score	0.163276 (rank : 76)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	90	Target Neighborhood Hits	82	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TN84	Gene names	Syt14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

SYTL1_MOUSE
NC score	0.163065 (rank : 77)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	90	Target Neighborhood Hits	314	Shared Neighborhood Hits	53
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

PA24D_MOUSE
NC score	0.161318 (rank : 78)	θ value	0.00665767 (rank : 44)
Query Neighborhood Hits	90	Target Neighborhood Hits	100	Shared Neighborhood Hits	67
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SYT14_HUMAN
NC score	0.160627 (rank : 79)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	90	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NB59, Q5THX7, Q707N3, Q707N4, Q707N5, Q707N6, Q707N7	Gene names	SYT14
Domain Architecture	No domain graphic available
Description	Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV).

BAIP3_HUMAN
NC score	0.157683 (rank : 80)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	90	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

SYTL3_MOUSE
NC score	0.150114 (rank : 81)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	90	Target Neighborhood Hits	110	Shared Neighborhood Hits	45
SwissProt Accessions	Q99N48, Q8C506, Q99N47, Q99N49, Q99N54, Q99N79	Gene names	Sytl3, Slp3
Domain Architecture
Description	Synaptotagmin-like protein 3 (Exophilin-6).

PA24D_HUMAN
NC score	0.143574 (rank : 82)	θ value	0.21417 (rank : 65)
Query Neighborhood Hits	90	Target Neighborhood Hits	97	Shared Neighborhood Hits	65
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

NEDD4_HUMAN
NC score	0.142010 (rank : 83)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	90	Target Neighborhood Hits	214	Shared Neighborhood Hits	77
SwissProt Accessions	P46934	Gene names	NEDD4, KIAA0093
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-).

NEDD4_MOUSE
NC score	0.140984 (rank : 84)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	90	Target Neighborhood Hits	212	Shared Neighborhood Hits	78
SwissProt Accessions	P46935, O08758, Q3UZI2, Q8BGB3	Gene names	Nedd4, Kiaa0093, Nedd-4, Nedd4a
Domain Architecture
Description	E3 ubiquitin-protein ligase NEDD4 (EC 6.3.2.-) (Neural precursor cell expressed developmentally down-regulated protein 4).

PA24B_MOUSE
NC score	0.137457 (rank : 85)	θ value	0.125558 (rank : 62)
Query Neighborhood Hits	90	Target Neighborhood Hits	102	Shared Neighborhood Hits	67
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

RIMS2_HUMAN
NC score	0.128177 (rank : 86)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	90	Target Neighborhood Hits	342	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

RIMS2_MOUSE
NC score	0.126512 (rank : 87)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	90	Target Neighborhood Hits	376	Shared Neighborhood Hits	65
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

K0528_HUMAN
NC score	0.125903 (rank : 88)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	90	Target Neighborhood Hits	96	Shared Neighborhood Hits	53
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
NC score	0.125813 (rank : 89)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	90	Target Neighborhood Hits	102	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

KPCG_MOUSE
NC score	0.125736 (rank : 90)	θ value	5.81887e-07 (rank : 28)
Query Neighborhood Hits	90	Target Neighborhood Hits	1123	Shared Neighborhood Hits	81
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_HUMAN
NC score	0.124276 (rank : 91)	θ value	7.59969e-07 (rank : 31)
Query Neighborhood Hits	90	Target Neighborhood Hits	1126	Shared Neighborhood Hits	81
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

RIMS1_HUMAN
NC score	0.121999 (rank : 92)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	90	Target Neighborhood Hits	437	Shared Neighborhood Hits	61
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

SMUF1_HUMAN
NC score	0.119486 (rank : 93)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	90	Target Neighborhood Hits	135	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HCE7, O75853, Q9UJT8	Gene names	SMURF1, KIAA1625
Domain Architecture
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) (hSMURF1).

SMUF1_MOUSE
NC score	0.118756 (rank : 94)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	90	Target Neighborhood Hits	142	Shared Neighborhood Hits	64
SwissProt Accessions	Q9CUN6, Q3U412, Q8K300	Gene names	Smurf1
Domain Architecture	No domain graphic available
Description	Smad ubiquitination regulatory factor 1 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1).

PA24E_MOUSE
NC score	0.113910 (rank : 95)	θ value	0.0563607 (rank : 60)
Query Neighborhood Hits	90	Target Neighborhood Hits	95	Shared Neighborhood Hits	61
SwissProt Accessions	Q50L42, Q8BX44	Gene names	Pla2g4e
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

PA24E_HUMAN
NC score	0.113634 (rank : 96)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	90	Target Neighborhood Hits	89	Shared Neighborhood Hits	62
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

SMUF2_HUMAN
NC score	0.113251 (rank : 97)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	90	Target Neighborhood Hits	142	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

KPCB_HUMAN
NC score	0.112858 (rank : 98)	θ value	1.69304e-06 (rank : 33)
Query Neighborhood Hits	90	Target Neighborhood Hits	1121	Shared Neighborhood Hits	81
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_MOUSE
NC score	0.111042 (rank : 99)	θ value	4.1701e-05 (rank : 36)
Query Neighborhood Hits	90	Target Neighborhood Hits	1067	Shared Neighborhood Hits	81
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCB_MOUSE
NC score	0.111038 (rank : 100)	θ value	3.19293e-05 (rank : 35)
Query Neighborhood Hits	90	Target Neighborhood Hits	1117	Shared Neighborhood Hits	81
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_HUMAN
NC score	0.109855 (rank : 101)	θ value	0.00020696 (rank : 38)
Query Neighborhood Hits	90	Target Neighborhood Hits	1070	Shared Neighborhood Hits	81
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

RFIP2_HUMAN
NC score	0.109208 (rank : 102)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	90	Target Neighborhood Hits	97	Shared Neighborhood Hits	52
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

PA24B_HUMAN
NC score	0.107032 (rank : 103)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	90	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

RASA3_HUMAN
NC score	0.103811 (rank : 104)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	90	Target Neighborhood Hits	166	Shared Neighborhood Hits	51
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA2_MOUSE
NC score	0.102045 (rank : 105)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	90	Target Neighborhood Hits	159	Shared Neighborhood Hits	55
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_HUMAN
NC score	0.097181 (rank : 106)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	90	Target Neighborhood Hits	157	Shared Neighborhood Hits	54
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

P3C2B_HUMAN
NC score	0.097106 (rank : 107)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	90	Target Neighborhood Hits	148	Shared Neighborhood Hits	47
SwissProt Accessions	O00750, O95666, Q5SW99	Gene names	PIK3C2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-beta) (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K).

UVRAG_HUMAN
NC score	0.096228 (rank : 108)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	90	Target Neighborhood Hits	150	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2Y5, O00392	Gene names	UVRAG
Domain Architecture	No domain graphic available
Description	UV radiation resistance-associated gene protein (p63).

RIMS4_MOUSE
NC score	0.093256 (rank : 109)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	90	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	P60191	Gene names	Rims4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

RIMS4_HUMAN
NC score	0.092685 (rank : 110)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	90	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H426, Q5JWT7	Gene names	RIMS4
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 4 (Rab3-interacting molecule 4) (RIM 4) (RIM4 gamma).

TAC2N_HUMAN
NC score	0.092331 (rank : 111)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	90	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N9U0	Gene names	MTAC2D1, C14orf47
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

PA24A_MOUSE
NC score	0.089449 (rank : 112)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	90	Target Neighborhood Hits	100	Shared Neighborhood Hits	58
SwissProt Accessions	P47713	Gene names	Pla2g4a, Cpla2, Pla2g4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

TAC2N_MOUSE
NC score	0.088001 (rank : 113)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	90	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q91XT6, Q9D4A0	Gene names	Mtac2d1
Domain Architecture
Description	Membrane targeting tandem C2 domain-containing protein 1 (Tandem C2 protein in nucleus) (Tac2-N).

PA24A_HUMAN
NC score	0.085902 (rank : 114)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	90	Target Neighborhood Hits	88	Shared Neighborhood Hits	58
SwissProt Accessions	P47712	Gene names	PLA2G4A, CPLA2, PLA2G4
Domain Architecture
Description	Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2- acylhydrolase); Lysophospholipase (EC 3.1.1.5)].

RASA3_MOUSE
NC score	0.085185 (rank : 115)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	90	Target Neighborhood Hits	144	Shared Neighborhood Hits	51
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

PLCD1_HUMAN
NC score	0.085067 (rank : 116)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	90	Target Neighborhood Hits	93	Shared Neighborhood Hits	46
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

PA24F_MOUSE
NC score	0.084852 (rank : 117)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	90	Target Neighborhood Hits	93	Shared Neighborhood Hits	63
SwissProt Accessions	Q50L41, Q80VQ8, Q80VV9	Gene names	Pla2g4f
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

P3C2A_MOUSE
NC score	0.082230 (rank : 118)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	90	Target Neighborhood Hits	181	Shared Neighborhood Hits	45
SwissProt Accessions	Q61194, Q61182	Gene names	Pik3c2a, Cpk
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) (Cpk-m) (p170).

P3C2A_HUMAN
NC score	0.081548 (rank : 119)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	90	Target Neighborhood Hits	188	Shared Neighborhood Hits	45
SwissProt Accessions	O00443	Gene names	PIK3C2A
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide (EC 2.7.1.154) (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha).

PA24F_HUMAN
NC score	0.076572 (rank : 120)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	90	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	Q68DD2, Q6ZMC8	Gene names	PLA2G4F
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 zeta (EC 3.1.1.4) (cPLA2-zeta) (Phospholipase A2 group IVF).

RIMS3_HUMAN
NC score	0.076536 (rank : 121)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	90	Target Neighborhood Hits	66	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UJD0, Q92511	Gene names	RIMS3, KIAA0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

PLCD1_MOUSE
NC score	0.072708 (rank : 122)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	90	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R3B1	Gene names	Plcd1, Plcd
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

RIMS3_MOUSE
NC score	0.071545 (rank : 123)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	90	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	Q80U57	Gene names	Rims3, Kiaa0237
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 3 (Nim3) (Rab-3- interacting molecule 3) (RIM 3) (RIM3 gamma).

INP4B_MOUSE
NC score	0.063651 (rank : 124)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	90	Target Neighborhood Hits	29	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P1Y8	Gene names	Inpp4b
Domain Architecture	No domain graphic available
Description	Type II inositol-3,4-bisphosphate 4-phosphatase (EC 3.1.3.66) (Inositol polyphosphate 4-phosphatase type II).

ITSN2_HUMAN
NC score	0.062498 (rank : 125)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	90	Target Neighborhood Hits	1173	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

ITSN2_MOUSE
NC score	0.056788 (rank : 126)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	90	Target Neighborhood Hits	1371	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

RGS3_HUMAN
NC score	0.053066 (rank : 127)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	90	Target Neighborhood Hits	1375	Shared Neighborhood Hits	43
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GANC_HUMAN
NC score	0.009059 (rank : 128)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	90	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TET4, Q52LQ4, Q8IWZ0, Q8IZM4, Q8IZM5	Gene names	GANC
Domain Architecture
Description	Neutral alpha-glucosidase C (EC 3.2.1.20).

CAD13_MOUSE
NC score	0.006232 (rank : 129)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	90	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTR5	Gene names	Cdh13
Domain Architecture
Description	Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin).

TITIN_HUMAN
NC score	0.004917 (rank : 130)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	90	Target Neighborhood Hits	2923	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ANGL4_HUMAN
NC score	0.004124 (rank : 131)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	90	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

UBP4_MOUSE
NC score	0.003173 (rank : 132)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	90	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

CAD13_HUMAN
NC score	0.002709 (rank : 133)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	90	Target Neighborhood Hits	156	Shared Neighborhood Hits	4
SwissProt Accessions	P55290, Q8TBX3	Gene names	CDH13, CDHH
Domain Architecture
Description	Cadherin-13 precursor (Truncated-cadherin) (T-cadherin) (T-cad) (Heart-cadherin) (H-cadherin) (P105).

HXD3_HUMAN
NC score	0.001898 (rank : 134)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	90	Target Neighborhood Hits	433	Shared Neighborhood Hits	3
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

HXD3_MOUSE
NC score	0.001425 (rank : 135)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	90	Target Neighborhood Hits	435	Shared Neighborhood Hits	3
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).