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Network neighborhood for query Sequence : PERF_HUMAN

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PERF_HUMAN
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PERF_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

PERF_MOUSE
θ value	0 (rank : 2)	NC score	0.976970 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

CO6_HUMAN
θ value	6.20254e-17 (rank : 3)	NC score	0.380613 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	331	Shared Neighborhood Hits	15
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO8A_MOUSE
θ value	2.69671e-12 (rank : 4)	NC score	0.406534 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	182	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_HUMAN
θ value	5.62301e-10 (rank : 5)	NC score	0.386702 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	200	Shared Neighborhood Hits	17
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO7_HUMAN
θ value	3.08544e-08 (rank : 6)	NC score	0.344235 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	278	Shared Neighborhood Hits	19
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8B_MOUSE
θ value	5.44631e-05 (rank : 7)	NC score	0.341186 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	224	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

RASL1_HUMAN
θ value	0.000121331 (rank : 8)	NC score	0.153469 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	142	Shared Neighborhood Hits	24
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

CO9_MOUSE
θ value	0.000786445 (rank : 9)	NC score	0.358435 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	153	Shared Neighborhood Hits	16
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

RASL1_MOUSE
θ value	0.000786445 (rank : 10)	NC score	0.147003 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

UN13B_MOUSE
θ value	0.00509761 (rank : 11)	NC score	0.160168 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	210	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

PA24D_HUMAN
θ value	0.00665767 (rank : 12)	NC score	0.084507 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

UN13A_HUMAN
θ value	0.00665767 (rank : 13)	NC score	0.153298 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	285	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	0.0252991 (rank : 14)	NC score	0.147600 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	217	Shared Neighborhood Hits	27
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CO8B_HUMAN
θ value	0.0431538 (rank : 15)	NC score	0.321945 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	199	Shared Neighborhood Hits	19
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

OTOF_HUMAN
θ value	0.0431538 (rank : 16)	NC score	0.143017 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	168	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
θ value	0.0431538 (rank : 17)	NC score	0.142653 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	196	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

FA62A_HUMAN
θ value	0.0563607 (rank : 18)	NC score	0.150585 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	168	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

CO9_HUMAN
θ value	0.0736092 (rank : 19)	NC score	0.335276 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

FA62A_MOUSE
θ value	0.0736092 (rank : 20)	NC score	0.146251 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	155	Shared Neighborhood Hits	27
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

ITCH_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.028588 (rank : 64)
Query Neighborhood Hits	48	Target Neighborhood Hits	162	Shared Neighborhood Hits	16
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

SSPO_MOUSE
θ value	0.62314 (rank : 22)	NC score	0.055940 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	800	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

BAI1_MOUSE
θ value	0.813845 (rank : 23)	NC score	0.054621 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	340	Shared Neighborhood Hits	13
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ITCH_MOUSE
θ value	0.813845 (rank : 24)	NC score	0.026419 (rank : 66)
Query Neighborhood Hits	48	Target Neighborhood Hits	127	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

RP3A_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.063102 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	510	Shared Neighborhood Hits	25
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

BAI1_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.054702 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

MYOF_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.110721 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	147	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

FAM5A_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.059225 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	O60477, Q6IPV6, Q6P1A0, Q8WU22	Gene names	FAM5A, DBC1, DBCCR1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein).

FAM5A_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.059132 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q920P3, Q80ZL2, Q812F0, Q8C1C9, Q920P4, Q9QXL0	Gene names	Fam5a, Brinp, Brinp1, Dbccr1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein homolog) (BMP/retinoic acid-inducible neural-specific protein 1).

RP3A_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.061028 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	305	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

PA24E_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.054137 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

DYSF_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.111725 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	170	Shared Neighborhood Hits	27
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

TSP2_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.057038 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	352	Shared Neighborhood Hits	14
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

CPNE7_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.024048 (rank : 67)
Query Neighborhood Hits	48	Target Neighborhood Hits	92	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

ITSN2_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.030208 (rank : 62)
Query Neighborhood Hits	48	Target Neighborhood Hits	1173	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

B2L10_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.028695 (rank : 63)
Query Neighborhood Hits	48	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0F3	Gene names	Bcl2l10, Boo, Diva
Domain Architecture
Description	Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti- apoptotic protein Boo) (Bcl-2 homolog Diva).

DOC2B_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.056477 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	150	Shared Neighborhood Hits	25
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

FA55D_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.021650 (rank : 68)
Query Neighborhood Hits	48	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q52KP5, Q8BKY4	Gene names	Fam55d
Domain Architecture	No domain graphic available
Description	Protein FAM55D precursor.

FAM5B_MOUSE
θ value	5.27518 (rank : 39)	NC score	0.057577 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

PA24B_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.063511 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

FAM5B_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.055115 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	55	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

TNR6_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.015141 (rank : 69)
Query Neighborhood Hits	48	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

BAI3_MOUSE
θ value	8.99809 (rank : 43)	NC score	0.049730 (rank : 61)
Query Neighborhood Hits	48	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

DOC2B_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.054016 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	169	Shared Neighborhood Hits	25
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

ITSN2_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.026795 (rank : 65)
Query Neighborhood Hits	48	Target Neighborhood Hits	1371	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

K0528_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.067467 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	96	Shared Neighborhood Hits	21
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_MOUSE
θ value	8.99809 (rank : 47)	NC score	0.067528 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

NARG1_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.010092 (rank : 70)
Query Neighborhood Hits	48	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

BAIP3_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.052221 (rank : 53)
Query Neighborhood Hits	48	Target Neighborhood Hits	108	Shared Neighborhood Hits	22
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

DOC2A_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.058481 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

DOC2A_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.056507 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	140	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DYSF_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.086127 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	162	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

PA24B_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.053141 (rank : 50)
Query Neighborhood Hits	48	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

PA24D_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.065718 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	100	Shared Neighborhood Hits	21
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PROP_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.058567 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	126	Shared Neighborhood Hits	13
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.062829 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

RASA2_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.051304 (rank : 59)
Query Neighborhood Hits	48	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA2_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.052454 (rank : 52)
Query Neighborhood Hits	48	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RASA3_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.053179 (rank : 49)
Query Neighborhood Hits	48	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.051998 (rank : 54)
Query Neighborhood Hits	48	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RASL2_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.096069 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

RFIP2_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.054216 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

TSP2_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.052932 (rank : 51)
Query Neighborhood Hits	48	Target Neighborhood Hits	359	Shared Neighborhood Hits	14
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

UN13D_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.058082 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	117	Shared Neighborhood Hits	21
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

UNC5A_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.051994 (rank : 55)
Query Neighborhood Hits	48	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5A_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.054428 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	203	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.051015 (rank : 60)
Query Neighborhood Hits	48	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.051416 (rank : 58)
Query Neighborhood Hits	48	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.051830 (rank : 56)
Query Neighborhood Hits	48	Target Neighborhood Hits	226	Shared Neighborhood Hits	12
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.051624 (rank : 57)
Query Neighborhood Hits	48	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

Hits sorted by NC score

PERF_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

PERF_MOUSE
NC score	0.976970 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	45	Shared Neighborhood Hits	27
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

CO8A_MOUSE
NC score	0.406534 (rank : 3)	θ value	2.69671e-12 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	182	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_HUMAN
NC score	0.386702 (rank : 4)	θ value	5.62301e-10 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	200	Shared Neighborhood Hits	17
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO6_HUMAN
NC score	0.380613 (rank : 5)	θ value	6.20254e-17 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	331	Shared Neighborhood Hits	15
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO9_MOUSE
NC score	0.358435 (rank : 6)	θ value	0.000786445 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	153	Shared Neighborhood Hits	16
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CO7_HUMAN
NC score	0.344235 (rank : 7)	θ value	3.08544e-08 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	278	Shared Neighborhood Hits	19
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8B_MOUSE
NC score	0.341186 (rank : 8)	θ value	5.44631e-05 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	224	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
NC score	0.335276 (rank : 9)	θ value	0.0736092 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO8B_HUMAN
NC score	0.321945 (rank : 10)	θ value	0.0431538 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	199	Shared Neighborhood Hits	19
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

UN13B_MOUSE
NC score	0.160168 (rank : 11)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	210	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

RASL1_HUMAN
NC score	0.153469 (rank : 12)	θ value	0.000121331 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	142	Shared Neighborhood Hits	24
SwissProt Accessions	O95294, Q52M03, Q96CC7	Gene names	RASAL1, RASAL
Domain Architecture
Description	RasGAP-activating-like protein 1.

UN13A_HUMAN
NC score	0.153298 (rank : 13)	θ value	0.00665767 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	285	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

FA62A_HUMAN
NC score	0.150585 (rank : 14)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	168	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BSJ8, O94848, Q6PJN4, Q9H6J1, Q9H6W2, Q9Y416	Gene names	FAM62A, KIAA0747, MBC2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

UN13B_HUMAN
NC score	0.147600 (rank : 15)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	217	Shared Neighborhood Hits	27
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

RASL1_MOUSE
NC score	0.147003 (rank : 16)	θ value	0.000786445 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	148	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z268	Gene names	Rasal1, Rasal
Domain Architecture
Description	RasGAP-activating-like protein 1.

FA62A_MOUSE
NC score	0.146251 (rank : 17)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	155	Shared Neighborhood Hits	27
SwissProt Accessions	Q3U7R1, Q8C8R1, Q91X62, Q9CVH0, Q9Z1X5, Q9Z1X6	Gene names	Fam62a, Mbc2
Domain Architecture	No domain graphic available
Description	Protein FAM62A (Membrane-bound C2 domain-containing protein).

OTOF_HUMAN
NC score	0.143017 (rank : 18)	θ value	0.0431538 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	168	Shared Neighborhood Hits	26
SwissProt Accessions	Q9HC10, Q9HC08, Q9HC09, Q9Y650	Gene names	OTOF, FER1L2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

OTOF_MOUSE
NC score	0.142653 (rank : 19)	θ value	0.0431538 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	196	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESF1, Q9ESF2	Gene names	Otof, Fer1l2
Domain Architecture
Description	Otoferlin (Fer-1-like protein 2).

DYSF_HUMAN
NC score	0.111725 (rank : 20)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	170	Shared Neighborhood Hits	27
SwissProt Accessions	O75923, O75696, Q9UEN7	Gene names	DYSF, FER1L1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

MYOF_HUMAN
NC score	0.110721 (rank : 21)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	147	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZM1, Q9HBU3, Q9NZM0, Q9ULL3, Q9Y4U4	Gene names	FER1L3, KIAA1207, MYOF
Domain Architecture
Description	Myoferlin (Fer-1-like protein 3).

RASL2_HUMAN
NC score	0.096069 (rank : 22)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	48	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	O43374, O60286, Q86UW3, Q96QU0	Gene names	RASA4, CAPRI, GAPL, KIAA0538
Domain Architecture
Description	Ras GTPase-activating protein 4 (RasGAP-activating-like protein 2) (Calcium-promoted Ras inactivator).

DYSF_MOUSE
NC score	0.086127 (rank : 23)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	48	Target Neighborhood Hits	162	Shared Neighborhood Hits	24
SwissProt Accessions	Q9ESD7, Q9QXC0	Gene names	Dysf, Fer1l1
Domain Architecture
Description	Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).

PA24D_HUMAN
NC score	0.084507 (rank : 24)	θ value	0.00665767 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	97	Shared Neighborhood Hits	21
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

K0528_MOUSE
NC score	0.067528 (rank : 25)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPS5, Q3TQY6, Q6A052, Q80VA1, Q8C0U3, Q8CID5, Q9CS85	Gene names	Kiaa0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

K0528_HUMAN
NC score	0.067467 (rank : 26)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	96	Shared Neighborhood Hits	21
SwissProt Accessions	Q86YS7, O60280, Q7Z619, Q86SU3	Gene names	KIAA0528
Domain Architecture	No domain graphic available
Description	Protein KIAA0528.

PA24D_MOUSE
NC score	0.065718 (rank : 27)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	48	Target Neighborhood Hits	100	Shared Neighborhood Hits	21
SwissProt Accessions	Q50L43, Q3TJC5	Gene names	Pla2g4d
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PA24B_MOUSE
NC score	0.063511 (rank : 28)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	Q4QQM1, Q80VV8, Q91W88	Gene names	Pla2g4b
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

RP3A_MOUSE
NC score	0.063102 (rank : 29)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	510	Shared Neighborhood Hits	25
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

PROP_MOUSE
NC score	0.062829 (rank : 30)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	48	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

RP3A_HUMAN
NC score	0.061028 (rank : 31)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	305	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

FAM5A_HUMAN
NC score	0.059225 (rank : 32)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	O60477, Q6IPV6, Q6P1A0, Q8WU22	Gene names	FAM5A, DBC1, DBCCR1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein).

FAM5A_MOUSE
NC score	0.059132 (rank : 33)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q920P3, Q80ZL2, Q812F0, Q8C1C9, Q920P4, Q9QXL0	Gene names	Fam5a, Brinp, Brinp1, Dbccr1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein homolog) (BMP/retinoic acid-inducible neural-specific protein 1).

PROP_HUMAN
NC score	0.058567 (rank : 34)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	48	Target Neighborhood Hits	126	Shared Neighborhood Hits	13
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

DOC2A_HUMAN
NC score	0.058481 (rank : 35)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	48	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q14183, Q6P4G4, Q7Z5G0, Q8IVX0	Gene names	DOC2A
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2).

UN13D_HUMAN
NC score	0.058082 (rank : 36)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	48	Target Neighborhood Hits	117	Shared Neighborhood Hits	21
SwissProt Accessions	Q70J99, Q9H7K5	Gene names	UNC13D
Domain Architecture	No domain graphic available
Description	Unc-13 homolog D (Munc13-4).

FAM5B_MOUSE
NC score	0.057577 (rank : 37)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

TSP2_MOUSE
NC score	0.057038 (rank : 38)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	352	Shared Neighborhood Hits	14
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

DOC2A_MOUSE
NC score	0.056507 (rank : 39)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	48	Target Neighborhood Hits	140	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TNF0	Gene names	Doc2a
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein alpha (Doc2-alpha).

DOC2B_HUMAN
NC score	0.056477 (rank : 40)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	150	Shared Neighborhood Hits	25
SwissProt Accessions	Q14184	Gene names	DOC2B
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

SSPO_MOUSE
NC score	0.055940 (rank : 41)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	800	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

FAM5B_HUMAN
NC score	0.055115 (rank : 42)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	55	Shared Neighborhood Hits	13
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

BAI1_HUMAN
NC score	0.054702 (rank : 43)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	375	Shared Neighborhood Hits	14
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
NC score	0.054621 (rank : 44)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	340	Shared Neighborhood Hits	13
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

UNC5A_MOUSE
NC score	0.054428 (rank : 45)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	48	Target Neighborhood Hits	203	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

RFIP2_HUMAN
NC score	0.054216 (rank : 46)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	48	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q7L804, Q9Y2F0	Gene names	RAB11FIP2, KIAA0941
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11).

PA24E_HUMAN
NC score	0.054137 (rank : 47)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q3MJ16, Q6ZSC0	Gene names	PLA2G4E
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 epsilon (EC 3.1.1.4) (cPLA2-epsilon) (Phospholipase A2 group IVE).

DOC2B_MOUSE
NC score	0.054016 (rank : 48)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	169	Shared Neighborhood Hits	25
SwissProt Accessions	P70169, Q6NXK3	Gene names	Doc2b
Domain Architecture	No domain graphic available
Description	Double C2-like domain-containing protein beta (Doc2-beta).

RASA3_HUMAN
NC score	0.053179 (rank : 49)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	48	Target Neighborhood Hits	166	Shared Neighborhood Hits	15
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

PA24B_HUMAN
NC score	0.053141 (rank : 50)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	48	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	O95712, Q59GF9, Q8TB10, Q9UKV7	Gene names	PLA2G4B
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 beta (EC 3.1.1.4) (cPLA2-beta) (Phospholipase A2 group IVB).

TSP2_HUMAN
NC score	0.052932 (rank : 51)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	48	Target Neighborhood Hits	359	Shared Neighborhood Hits	14
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

RASA2_MOUSE
NC score	0.052454 (rank : 52)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	48	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

BAIP3_HUMAN
NC score	0.052221 (rank : 53)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	48	Target Neighborhood Hits	108	Shared Neighborhood Hits	22
SwissProt Accessions	O94812, O94839, Q2M226, Q658J2, Q76N05, Q96RZ3, Q9UJK1	Gene names	BAIAP3, KIAA0734
Domain Architecture	No domain graphic available
Description	BAI1-associated protein 3 (BAP3).

RASA3_MOUSE
NC score	0.051998 (rank : 54)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	48	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

UNC5A_HUMAN
NC score	0.051994 (rank : 55)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	48	Target Neighborhood Hits	198	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5C_HUMAN
NC score	0.051830 (rank : 56)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	48	Target Neighborhood Hits	226	Shared Neighborhood Hits	12
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
NC score	0.051624 (rank : 57)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	48	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5B_MOUSE
NC score	0.051416 (rank : 58)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	48	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

RASA2_HUMAN
NC score	0.051304 (rank : 59)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	48	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

UNC5B_HUMAN
NC score	0.051015 (rank : 60)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	48	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

BAI3_MOUSE
NC score	0.049730 (rank : 61)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

ITSN2_HUMAN
NC score	0.030208 (rank : 62)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	1173	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

B2L10_MOUSE
NC score	0.028695 (rank : 63)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0F3	Gene names	Bcl2l10, Boo, Diva
Domain Architecture
Description	Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti- apoptotic protein Boo) (Bcl-2 homolog Diva).

ITCH_HUMAN
NC score	0.028588 (rank : 64)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	162	Shared Neighborhood Hits	16
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

ITSN2_MOUSE
NC score	0.026795 (rank : 65)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	1371	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

ITCH_MOUSE
NC score	0.026419 (rank : 66)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	127	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C863, O54971	Gene names	Itch
Domain Architecture
Description	Itchy E3 ubiquitin protein ligase (EC 6.3.2.-).

CPNE7_HUMAN
NC score	0.024048 (rank : 67)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	92	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UBL6	Gene names	CPNE7
Domain Architecture
Description	Copine-7 (Copine VII).

FA55D_MOUSE
NC score	0.021650 (rank : 68)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q52KP5, Q8BKY4	Gene names	Fam55d
Domain Architecture	No domain graphic available
Description	Protein FAM55D precursor.

TNR6_HUMAN
NC score	0.015141 (rank : 69)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

NARG1_MOUSE
NC score	0.010092 (rank : 70)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).