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Network neighborhood for query Sequence : CO9_MOUSE

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CO9_MOUSE
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CO9_HUMAN
θ value	0 (rank : 1)	NC score	0.982218 (rank : 2)
Query Neighborhood Hits	153	Target Neighborhood Hits	147	Shared Neighborhood Hits	119
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	153	Target Neighborhood Hits	153	Shared Neighborhood Hits	153
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CO8A_HUMAN
θ value	2.17053e-70 (rank : 3)	NC score	0.822315 (rank : 5)
Query Neighborhood Hits	153	Target Neighborhood Hits	200	Shared Neighborhood Hits	116
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	2.3998e-69 (rank : 4)	NC score	0.832474 (rank : 4)
Query Neighborhood Hits	153	Target Neighborhood Hits	182	Shared Neighborhood Hits	108
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_MOUSE
θ value	2.10232e-65 (rank : 5)	NC score	0.818822 (rank : 6)
Query Neighborhood Hits	153	Target Neighborhood Hits	224	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_HUMAN
θ value	8.83269e-64 (rank : 6)	NC score	0.835156 (rank : 3)
Query Neighborhood Hits	153	Target Neighborhood Hits	199	Shared Neighborhood Hits	110
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO6_HUMAN
θ value	5.0155e-59 (rank : 7)	NC score	0.740820 (rank : 7)
Query Neighborhood Hits	153	Target Neighborhood Hits	331	Shared Neighborhood Hits	121
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	2.18062e-54 (rank : 8)	NC score	0.725225 (rank : 8)
Query Neighborhood Hits	153	Target Neighborhood Hits	278	Shared Neighborhood Hits	116
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

VLDLR_HUMAN
θ value	1.38499e-08 (rank : 9)	NC score	0.413808 (rank : 11)
Query Neighborhood Hits	153	Target Neighborhood Hits	383	Shared Neighborhood Hits	107
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

PERF_MOUSE
θ value	1.53129e-07 (rank : 10)	NC score	0.422343 (rank : 10)
Query Neighborhood Hits	153	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

CORIN_HUMAN
θ value	1.99992e-07 (rank : 11)	NC score	0.261253 (rank : 39)
Query Neighborhood Hits	153	Target Neighborhood Hits	453	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

LRP4_MOUSE
θ value	4.45536e-07 (rank : 12)	NC score	0.408732 (rank : 14)
Query Neighborhood Hits	153	Target Neighborhood Hits	351	Shared Neighborhood Hits	107
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

SORL_HUMAN
θ value	4.45536e-07 (rank : 13)	NC score	0.395814 (rank : 22)
Query Neighborhood Hits	153	Target Neighborhood Hits	440	Shared Neighborhood Hits	103
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	4.45536e-07 (rank : 14)	NC score	0.398130 (rank : 20)
Query Neighborhood Hits	153	Target Neighborhood Hits	439	Shared Neighborhood Hits	103
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

VLDLR_MOUSE
θ value	5.81887e-07 (rank : 15)	NC score	0.410339 (rank : 12)
Query Neighborhood Hits	153	Target Neighborhood Hits	360	Shared Neighborhood Hits	107
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LDLR_HUMAN
θ value	9.92553e-07 (rank : 16)	NC score	0.398745 (rank : 18)
Query Neighborhood Hits	153	Target Neighborhood Hits	375	Shared Neighborhood Hits	112
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP2_HUMAN
θ value	9.92553e-07 (rank : 17)	NC score	0.393334 (rank : 23)
Query Neighborhood Hits	153	Target Neighborhood Hits	573	Shared Neighborhood Hits	124
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

CORIN_MOUSE
θ value	1.69304e-06 (rank : 18)	NC score	0.255880 (rank : 40)
Query Neighborhood Hits	153	Target Neighborhood Hits	451	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LRP4_HUMAN
θ value	2.21117e-06 (rank : 19)	NC score	0.409663 (rank : 13)
Query Neighborhood Hits	153	Target Neighborhood Hits	355	Shared Neighborhood Hits	110
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LDLR_MOUSE
θ value	2.88788e-06 (rank : 20)	NC score	0.407622 (rank : 15)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	110
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1_HUMAN
θ value	2.88788e-06 (rank : 21)	NC score	0.387794 (rank : 28)
Query Neighborhood Hits	153	Target Neighborhood Hits	617	Shared Neighborhood Hits	128
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP1B_HUMAN
θ value	4.92598e-06 (rank : 22)	NC score	0.389096 (rank : 27)
Query Neighborhood Hits	153	Target Neighborhood Hits	602	Shared Neighborhood Hits	126
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	1.09739e-05 (rank : 23)	NC score	0.389152 (rank : 26)
Query Neighborhood Hits	153	Target Neighborhood Hits	606	Shared Neighborhood Hits	127
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP6_HUMAN
θ value	1.43324e-05 (rank : 24)	NC score	0.406735 (rank : 16)
Query Neighborhood Hits	153	Target Neighborhood Hits	235	Shared Neighborhood Hits	89
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	1.87187e-05 (rank : 25)	NC score	0.406482 (rank : 17)
Query Neighborhood Hits	153	Target Neighborhood Hits	232	Shared Neighborhood Hits	88
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

ST14_HUMAN
θ value	3.19293e-05 (rank : 26)	NC score	0.253741 (rank : 42)
Query Neighborhood Hits	153	Target Neighborhood Hits	409	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	3.19293e-05 (rank : 27)	NC score	0.249997 (rank : 43)
Query Neighborhood Hits	153	Target Neighborhood Hits	419	Shared Neighborhood Hits	104
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

LRP5_HUMAN
θ value	4.1701e-05 (rank : 28)	NC score	0.398400 (rank : 19)
Query Neighborhood Hits	153	Target Neighborhood Hits	224	Shared Neighborhood Hits	82
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	0.000121331 (rank : 29)	NC score	0.397017 (rank : 21)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

PGBM_MOUSE
θ value	0.000461057 (rank : 30)	NC score	0.211631 (rank : 48)
Query Neighborhood Hits	153	Target Neighborhood Hits	1073	Shared Neighborhood Hits	131
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TSP2_HUMAN
θ value	0.000461057 (rank : 31)	NC score	0.192524 (rank : 58)
Query Neighborhood Hits	153	Target Neighborhood Hits	359	Shared Neighborhood Hits	80
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

CFAI_MOUSE
θ value	0.000602161 (rank : 32)	NC score	0.190423 (rank : 61)
Query Neighborhood Hits	153	Target Neighborhood Hits	290	Shared Neighborhood Hits	77
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

LRP8_MOUSE
θ value	0.000602161 (rank : 33)	NC score	0.389340 (rank : 25)
Query Neighborhood Hits	153	Target Neighborhood Hits	385	Shared Neighborhood Hits	108
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

PERF_HUMAN
θ value	0.000786445 (rank : 34)	NC score	0.358435 (rank : 34)
Query Neighborhood Hits	153	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

SSPO_MOUSE
θ value	0.000786445 (rank : 35)	NC score	0.340799 (rank : 35)
Query Neighborhood Hits	153	Target Neighborhood Hits	800	Shared Neighborhood Hits	133
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

LRP12_MOUSE
θ value	0.00134147 (rank : 36)	NC score	0.362697 (rank : 32)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

TSP2_MOUSE
θ value	0.00134147 (rank : 37)	NC score	0.194626 (rank : 56)
Query Neighborhood Hits	153	Target Neighborhood Hits	352	Shared Neighborhood Hits	84
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

SPON1_MOUSE
θ value	0.00175202 (rank : 38)	NC score	0.161882 (rank : 84)
Query Neighborhood Hits	153	Target Neighborhood Hits	123	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

LRP12_HUMAN
θ value	0.00298849 (rank : 39)	NC score	0.360694 (rank : 33)
Query Neighborhood Hits	153	Target Neighborhood Hits	205	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP8_HUMAN
θ value	0.00298849 (rank : 40)	NC score	0.389708 (rank : 24)
Query Neighborhood Hits	153	Target Neighborhood Hits	346	Shared Neighborhood Hits	111
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

NOTC3_MOUSE
θ value	0.00390308 (rank : 41)	NC score	0.156698 (rank : 90)
Query Neighborhood Hits	153	Target Neighborhood Hits	975	Shared Neighborhood Hits	107
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PGBM_HUMAN
θ value	0.00390308 (rank : 42)	NC score	0.205497 (rank : 49)
Query Neighborhood Hits	153	Target Neighborhood Hits	1113	Shared Neighborhood Hits	130
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LRP10_MOUSE
θ value	0.00665767 (rank : 43)	NC score	0.382692 (rank : 30)
Query Neighborhood Hits	153	Target Neighborhood Hits	169	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

NETO1_HUMAN
θ value	0.00665767 (rank : 44)	NC score	0.175465 (rank : 68)
Query Neighborhood Hits	153	Target Neighborhood Hits	110	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	0.00665767 (rank : 45)	NC score	0.175074 (rank : 69)
Query Neighborhood Hits	153	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

TMPS6_MOUSE
θ value	0.00665767 (rank : 46)	NC score	0.179623 (rank : 67)
Query Neighborhood Hits	153	Target Neighborhood Hits	341	Shared Neighborhood Hits	87
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

CR001_HUMAN
θ value	0.0113563 (rank : 47)	NC score	0.295447 (rank : 36)
Query Neighborhood Hits	153	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
θ value	0.0113563 (rank : 48)	NC score	0.293256 (rank : 37)
Query Neighborhood Hits	153	Target Neighborhood Hits	67	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

LRP10_HUMAN
θ value	0.0113563 (rank : 49)	NC score	0.386212 (rank : 29)
Query Neighborhood Hits	153	Target Neighborhood Hits	197	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP3_HUMAN
θ value	0.0113563 (rank : 50)	NC score	0.378915 (rank : 31)
Query Neighborhood Hits	153	Target Neighborhood Hits	280	Shared Neighborhood Hits	85
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

CFAI_HUMAN
θ value	0.0193708 (rank : 51)	NC score	0.197043 (rank : 52)
Query Neighborhood Hits	153	Target Neighborhood Hits	289	Shared Neighborhood Hits	76
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

ENTK_HUMAN
θ value	0.0193708 (rank : 52)	NC score	0.145227 (rank : 102)
Query Neighborhood Hits	153	Target Neighborhood Hits	310	Shared Neighborhood Hits	71
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

RXFP1_HUMAN
θ value	0.0193708 (rank : 53)	NC score	0.095038 (rank : 241)
Query Neighborhood Hits	153	Target Neighborhood Hits	816	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HBX9	Gene names	RXFP1, LGR7
Domain Architecture
Description	Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-rich repeat-containing G-protein coupled receptor 7).

RXFP2_HUMAN
θ value	0.0193708 (rank : 54)	NC score	0.117705 (rank : 162)
Query Neighborhood Hits	153	Target Neighborhood Hits	736	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

SPON1_HUMAN
θ value	0.0193708 (rank : 55)	NC score	0.149527 (rank : 99)
Query Neighborhood Hits	153	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

NOTC3_HUMAN
θ value	0.0252991 (rank : 56)	NC score	0.155618 (rank : 92)
Query Neighborhood Hits	153	Target Neighborhood Hits	1062	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

MFRP_MOUSE
θ value	0.0330416 (rank : 57)	NC score	0.198605 (rank : 51)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

TMPS6_HUMAN
θ value	0.0330416 (rank : 58)	NC score	0.189205 (rank : 62)
Query Neighborhood Hits	153	Target Neighborhood Hits	338	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

FA12_HUMAN
θ value	0.0431538 (rank : 59)	NC score	0.106124 (rank : 204)
Query Neighborhood Hits	153	Target Neighborhood Hits	425	Shared Neighborhood Hits	79
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

TMPS9_MOUSE
θ value	0.0431538 (rank : 60)	NC score	0.120881 (rank : 156)
Query Neighborhood Hits	153	Target Neighborhood Hits	296	Shared Neighborhood Hits	62
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMPS7_MOUSE
θ value	0.0563607 (rank : 61)	NC score	0.196388 (rank : 53)
Query Neighborhood Hits	153	Target Neighborhood Hits	275	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

CUBN_HUMAN
θ value	0.0736092 (rank : 62)	NC score	0.154848 (rank : 93)
Query Neighborhood Hits	153	Target Neighborhood Hits	482	Shared Neighborhood Hits	107
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

HGFA_HUMAN
θ value	0.0736092 (rank : 63)	NC score	0.111380 (rank : 189)
Query Neighborhood Hits	153	Target Neighborhood Hits	436	Shared Neighborhood Hits	87
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

NOTC1_MOUSE
θ value	0.0736092 (rank : 64)	NC score	0.172785 (rank : 71)
Query Neighborhood Hits	153	Target Neighborhood Hits	916	Shared Neighborhood Hits	104
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	0.0736092 (rank : 65)	NC score	0.167389 (rank : 77)
Query Neighborhood Hits	153	Target Neighborhood Hits	1113	Shared Neighborhood Hits	105
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	0.0736092 (rank : 66)	NC score	0.168450 (rank : 75)
Query Neighborhood Hits	153	Target Neighborhood Hits	1069	Shared Neighborhood Hits	104
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CD320_HUMAN
θ value	0.0961366 (rank : 67)	NC score	0.456380 (rank : 9)
Query Neighborhood Hits	153	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

NOTC1_HUMAN
θ value	0.0961366 (rank : 68)	NC score	0.166179 (rank : 78)
Query Neighborhood Hits	153	Target Neighborhood Hits	906	Shared Neighborhood Hits	100
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DLL4_HUMAN
θ value	0.125558 (rank : 69)	NC score	0.170366 (rank : 73)
Query Neighborhood Hits	153	Target Neighborhood Hits	435	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

TMPS7_HUMAN
θ value	0.125558 (rank : 70)	NC score	0.194685 (rank : 55)
Query Neighborhood Hits	153	Target Neighborhood Hits	275	Shared Neighborhood Hits	71
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

HGFA_MOUSE
θ value	0.163984 (rank : 71)	NC score	0.110845 (rank : 192)
Query Neighborhood Hits	153	Target Neighborhood Hits	419	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

CUBN_MOUSE
θ value	0.21417 (rank : 72)	NC score	0.161146 (rank : 85)
Query Neighborhood Hits	153	Target Neighborhood Hits	477	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

ENTK_MOUSE
θ value	0.21417 (rank : 73)	NC score	0.139596 (rank : 109)
Query Neighborhood Hits	153	Target Neighborhood Hits	338	Shared Neighborhood Hits	75
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FAT2_HUMAN
θ value	0.21417 (rank : 74)	NC score	0.066388 (rank : 358)
Query Neighborhood Hits	153	Target Neighborhood Hits	507	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

DLL3_MOUSE
θ value	0.279714 (rank : 75)	NC score	0.163835 (rank : 82)
Query Neighborhood Hits	153	Target Neighborhood Hits	399	Shared Neighborhood Hits	90
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

NOTC4_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.155877 (rank : 91)
Query Neighborhood Hits	153	Target Neighborhood Hits	905	Shared Neighborhood Hits	102
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

RXFP2_MOUSE
θ value	0.47712 (rank : 77)	NC score	0.102232 (rank : 220)
Query Neighborhood Hits	153	Target Neighborhood Hits	760	Shared Neighborhood Hits	62
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

SLIT3_HUMAN
θ value	0.47712 (rank : 78)	NC score	0.116153 (rank : 168)
Query Neighborhood Hits	153	Target Neighborhood Hits	682	Shared Neighborhood Hits	94
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

DLL4_MOUSE
θ value	0.62314 (rank : 79)	NC score	0.164751 (rank : 79)
Query Neighborhood Hits	153	Target Neighborhood Hits	440	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

JAG2_MOUSE
θ value	0.62314 (rank : 80)	NC score	0.171341 (rank : 72)
Query Neighborhood Hits	153	Target Neighborhood Hits	504	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LRP11_MOUSE
θ value	0.62314 (rank : 81)	NC score	0.281954 (rank : 38)
Query Neighborhood Hits	153	Target Neighborhood Hits	81	Shared Neighborhood Hits	65
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

NETO2_HUMAN
θ value	0.62314 (rank : 82)	NC score	0.149918 (rank : 98)
Query Neighborhood Hits	153	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	0.62314 (rank : 83)	NC score	0.150782 (rank : 95)
Query Neighborhood Hits	153	Target Neighborhood Hits	113	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

SLIT1_MOUSE
θ value	0.62314 (rank : 84)	NC score	0.122368 (rank : 154)
Query Neighborhood Hits	153	Target Neighborhood Hits	715	Shared Neighborhood Hits	100
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SPIT1_MOUSE
θ value	0.62314 (rank : 85)	NC score	0.203345 (rank : 50)
Query Neighborhood Hits	153	Target Neighborhood Hits	96	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

CRUM2_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.159192 (rank : 88)
Query Neighborhood Hits	153	Target Neighborhood Hits	453	Shared Neighborhood Hits	91
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DLL1_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.174022 (rank : 70)
Query Neighborhood Hits	153	Target Neighborhood Hits	455	Shared Neighborhood Hits	103
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

FATH_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.089916 (rank : 261)
Query Neighborhood Hits	153	Target Neighborhood Hits	570	Shared Neighborhood Hits	87
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

KPCA_MOUSE
θ value	0.813845 (rank : 89)	NC score	-0.000675 (rank : 559)
Query Neighborhood Hits	153	Target Neighborhood Hits	1067	Shared Neighborhood Hits	6
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

SEM5B_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.101273 (rank : 222)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SLIT1_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.118006 (rank : 160)
Query Neighborhood Hits	153	Target Neighborhood Hits	700	Shared Neighborhood Hits	95
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SPON2_MOUSE
θ value	0.813845 (rank : 92)	NC score	0.124064 (rank : 151)
Query Neighborhood Hits	153	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

TIE1_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.035358 (rank : 550)
Query Neighborhood Hits	153	Target Neighborhood Hits	1241	Shared Neighborhood Hits	76
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

LRP11_HUMAN
θ value	1.06291 (rank : 94)	NC score	0.254288 (rank : 41)
Query Neighborhood Hits	153	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

NOTC4_MOUSE
θ value	1.06291 (rank : 95)	NC score	0.145873 (rank : 101)
Query Neighborhood Hits	153	Target Neighborhood Hits	872	Shared Neighborhood Hits	101
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PROP_MOUSE
θ value	1.06291 (rank : 96)	NC score	0.160593 (rank : 86)
Query Neighborhood Hits	153	Target Neighborhood Hits	165	Shared Neighborhood Hits	32
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SPIT1_HUMAN
θ value	1.06291 (rank : 97)	NC score	0.217567 (rank : 45)
Query Neighborhood Hits	153	Target Neighborhood Hits	100	Shared Neighborhood Hits	57
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

ADAM7_MOUSE
θ value	1.38821 (rank : 98)	NC score	0.026458 (rank : 552)
Query Neighborhood Hits	153	Target Neighborhood Hits	200	Shared Neighborhood Hits	39
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

BAI1_HUMAN
θ value	1.38821 (rank : 99)	NC score	0.100797 (rank : 225)
Query Neighborhood Hits	153	Target Neighborhood Hits	375	Shared Neighborhood Hits	38
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CELR1_HUMAN
θ value	1.38821 (rank : 100)	NC score	0.060504 (rank : 415)
Query Neighborhood Hits	153	Target Neighborhood Hits	613	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

LTB1L_MOUSE
θ value	1.38821 (rank : 101)	NC score	0.140533 (rank : 108)
Query Neighborhood Hits	153	Target Neighborhood Hits	514	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.38821 (rank : 102)	NC score	0.134086 (rank : 120)
Query Neighborhood Hits	153	Target Neighborhood Hits	479	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MMRN1_HUMAN
θ value	1.38821 (rank : 103)	NC score	0.073685 (rank : 313)
Query Neighborhood Hits	153	Target Neighborhood Hits	636	Shared Neighborhood Hits	61
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

TMPS9_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.122674 (rank : 153)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

CELR1_MOUSE
θ value	1.81305 (rank : 105)	NC score	0.059388 (rank : 425)
Query Neighborhood Hits	153	Target Neighborhood Hits	617	Shared Neighborhood Hits	81
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

KPCA_HUMAN
θ value	1.81305 (rank : 106)	NC score	-0.001280 (rank : 560)
Query Neighborhood Hits	153	Target Neighborhood Hits	1070	Shared Neighborhood Hits	6
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

TDGF2_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.091286 (rank : 250)
Query Neighborhood Hits	153	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TSP1_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.187214 (rank : 63)
Query Neighborhood Hits	153	Target Neighborhood Hits	389	Shared Neighborhood Hits	86
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	1.81305 (rank : 109)	NC score	0.186162 (rank : 64)
Query Neighborhood Hits	153	Target Neighborhood Hits	396	Shared Neighborhood Hits	87
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

AGRIN_HUMAN
θ value	2.36792 (rank : 110)	NC score	0.128401 (rank : 139)
Query Neighborhood Hits	153	Target Neighborhood Hits	582	Shared Neighborhood Hits	91
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CRUM1_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.160466 (rank : 87)
Query Neighborhood Hits	153	Target Neighborhood Hits	444	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

HABP2_MOUSE
θ value	2.36792 (rank : 112)	NC score	0.125921 (rank : 147)
Query Neighborhood Hits	153	Target Neighborhood Hits	445	Shared Neighborhood Hits	95
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

SLIT3_MOUSE
θ value	2.36792 (rank : 113)	NC score	0.109515 (rank : 196)
Query Neighborhood Hits	153	Target Neighborhood Hits	700	Shared Neighborhood Hits	89
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TDGF1_MOUSE
θ value	2.36792 (rank : 114)	NC score	0.099904 (rank : 229)
Query Neighborhood Hits	153	Target Neighborhood Hits	146	Shared Neighborhood Hits	62
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

CSPG2_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.100889 (rank : 224)
Query Neighborhood Hits	153	Target Neighborhood Hits	711	Shared Neighborhood Hits	79
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DLL3_HUMAN
θ value	3.0926 (rank : 116)	NC score	0.158248 (rank : 89)
Query Neighborhood Hits	153	Target Neighborhood Hits	419	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

SEM5B_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.104025 (rank : 211)
Query Neighborhood Hits	153	Target Neighborhood Hits	190	Shared Neighborhood Hits	38
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SPON2_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.103895 (rank : 212)
Query Neighborhood Hits	153	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

CSPG2_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.100766 (rank : 226)
Query Neighborhood Hits	153	Target Neighborhood Hits	681	Shared Neighborhood Hits	78
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

DLL1_MOUSE
θ value	4.03905 (rank : 120)	NC score	0.170206 (rank : 74)
Query Neighborhood Hits	153	Target Neighborhood Hits	456	Shared Neighborhood Hits	99
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

JAG2_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.168349 (rank : 76)
Query Neighborhood Hits	153	Target Neighborhood Hits	491	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

MFRP_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.190884 (rank : 59)
Query Neighborhood Hits	153	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NAL10_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.007974 (rank : 555)
Query Neighborhood Hits	153	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

PROP_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.150722 (rank : 96)
Query Neighborhood Hits	153	Target Neighborhood Hits	126	Shared Neighborhood Hits	31
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

CRUM1_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.164714 (rank : 80)
Query Neighborhood Hits	153	Target Neighborhood Hits	457	Shared Neighborhood Hits	96
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FA9_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.112335 (rank : 183)
Query Neighborhood Hits	153	Target Neighborhood Hits	421	Shared Neighborhood Hits	97
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FAM5B_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.047980 (rank : 546)
Query Neighborhood Hits	153	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

NRX1A_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.056023 (rank : 464)
Query Neighborhood Hits	153	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.056252 (rank : 462)
Query Neighborhood Hits	153	Target Neighborhood Hits	164	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

TDGF1_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.086222 (rank : 275)
Query Neighborhood Hits	153	Target Neighborhood Hits	132	Shared Neighborhood Hits	59
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TIE1_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.034829 (rank : 551)
Query Neighborhood Hits	153	Target Neighborhood Hits	1266	Shared Neighborhood Hits	75
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

BAI1_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.097959 (rank : 233)
Query Neighborhood Hits	153	Target Neighborhood Hits	340	Shared Neighborhood Hits	32
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CELR3_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.062617 (rank : 391)
Query Neighborhood Hits	153	Target Neighborhood Hits	680	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CLUS_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.011373 (rank : 554)
Query Neighborhood Hits	153	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P10909, P11380, P11381, Q7Z5B9	Gene names	CLU
Domain Architecture
Description	Clusterin precursor (Complement-associated protein SP-40,40) (Complement cytolysis inhibitor) (CLI) (NA1/NA2) (Apolipoprotein J) (Apo-J) (Testosterone-repressed prostate message 2) (TRPM-2) [Contains: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)].

DDX49_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.002956 (rank : 558)
Query Neighborhood Hits	153	Target Neighborhood Hits	223	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

MEGF6_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.143859 (rank : 103)
Query Neighborhood Hits	153	Target Neighborhood Hits	671	Shared Neighborhood Hits	105
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MFGM_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.083207 (rank : 282)
Query Neighborhood Hits	153	Target Neighborhood Hits	233	Shared Neighborhood Hits	66
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

UNC5C_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.116126 (rank : 169)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	25
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

CFC1_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.098455 (rank : 232)
Query Neighborhood Hits	153	Target Neighborhood Hits	148	Shared Neighborhood Hits	64
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.097034 (rank : 235)
Query Neighborhood Hits	153	Target Neighborhood Hits	125	Shared Neighborhood Hits	62
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

DLK_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.141148 (rank : 106)
Query Neighborhood Hits	153	Target Neighborhood Hits	374	Shared Neighborhood Hits	85
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

FAM5B_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.046068 (rank : 547)
Query Neighborhood Hits	153	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

FAM5C_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.035546 (rank : 549)
Query Neighborhood Hits	153	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q76B58, O95726	Gene names	FAM5C, DBCCR1L, DBCCR1L1
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor (DBCCR1-like protein 1).

FAM5C_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.036789 (rank : 548)
Query Neighborhood Hits	153	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q499E0, Q8K0R9	Gene names	Fam5c
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor.

JAG1_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.164574 (rank : 81)
Query Neighborhood Hits	153	Target Neighborhood Hits	514	Shared Neighborhood Hits	95
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

NID1_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.195267 (rank : 54)
Query Neighborhood Hits	153	Target Neighborhood Hits	335	Shared Neighborhood Hits	74
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PIWL1_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.004120 (rank : 557)
Query Neighborhood Hits	153	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JMB7	Gene names	Piwil1, Miwi
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

RSPO2_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.023762 (rank : 553)
Query Neighborhood Hits	153	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

SHE_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.004178 (rank : 556)
Query Neighborhood Hits	153	Target Neighborhood Hits	164	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

TENA_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.133881 (rank : 122)
Query Neighborhood Hits	153	Target Neighborhood Hits	631	Shared Neighborhood Hits	95
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.134004 (rank : 121)
Query Neighborhood Hits	153	Target Neighborhood Hits	596	Shared Neighborhood Hits	98
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TMPS3_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.104431 (rank : 209)
Query Neighborhood Hits	153	Target Neighborhood Hits	245	Shared Neighborhood Hits	64
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

UROK_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.076889 (rank : 297)
Query Neighborhood Hits	153	Target Neighborhood Hits	272	Shared Neighborhood Hits	73
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ACRO_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.063508 (rank : 375)
Query Neighborhood Hits	153	Target Neighborhood Hits	291	Shared Neighborhood Hits	22
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.061960 (rank : 399)
Query Neighborhood Hits	153	Target Neighborhood Hits	185	Shared Neighborhood Hits	21
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

APOA_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.056434 (rank : 460)
Query Neighborhood Hits	153	Target Neighborhood Hits	221	Shared Neighborhood Hits	24
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

ASTN_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.050469 (rank : 538)
Query Neighborhood Hits	153	Target Neighborhood Hits	98	Shared Neighborhood Hits	29
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATRN_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.082827 (rank : 283)
Query Neighborhood Hits	153	Target Neighborhood Hits	525	Shared Neighborhood Hits	87
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.078852 (rank : 293)
Query Neighborhood Hits	153	Target Neighborhood Hits	519	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ATS12_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.067523 (rank : 349)
Query Neighborhood Hits	153	Target Neighborhood Hits	251	Shared Neighborhood Hits	23
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.070243 (rank : 336)
Query Neighborhood Hits	153	Target Neighborhood Hits	220	Shared Neighborhood Hits	24
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS13_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.089637 (rank : 263)
Query Neighborhood Hits	153	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.082273 (rank : 288)
Query Neighborhood Hits	153	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS14_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.064291 (rank : 370)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS15_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.065266 (rank : 364)
Query Neighborhood Hits	153	Target Neighborhood Hits	151	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS16_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.075778 (rank : 302)
Query Neighborhood Hits	153	Target Neighborhood Hits	208	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.070841 (rank : 330)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	25
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS17_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.068953 (rank : 342)
Query Neighborhood Hits	153	Target Neighborhood Hits	194	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS18_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.073682 (rank : 314)
Query Neighborhood Hits	153	Target Neighborhood Hits	169	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.073764 (rank : 312)
Query Neighborhood Hits	153	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.069948 (rank : 339)
Query Neighborhood Hits	153	Target Neighborhood Hits	159	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.069690 (rank : 340)
Query Neighborhood Hits	153	Target Neighborhood Hits	158	Shared Neighborhood Hits	25
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS20_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.072304 (rank : 322)
Query Neighborhood Hits	153	Target Neighborhood Hits	192	Shared Neighborhood Hits	35
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.076206 (rank : 299)
Query Neighborhood Hits	153	Target Neighborhood Hits	225	Shared Neighborhood Hits	38
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.072563 (rank : 318)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	25
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.069661 (rank : 341)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.070256 (rank : 335)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	26
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS4_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.054023 (rank : 488)
Query Neighborhood Hits	153	Target Neighborhood Hits	138	Shared Neighborhood Hits	26
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.056222 (rank : 463)
Query Neighborhood Hits	153	Target Neighborhood Hits	145	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS5_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.054121 (rank : 487)
Query Neighborhood Hits	153	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS5_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.066503 (rank : 357)
Query Neighborhood Hits	153	Target Neighborhood Hits	147	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS6_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.074593 (rank : 307)
Query Neighborhood Hits	153	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS7_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.063851 (rank : 373)
Query Neighborhood Hits	153	Target Neighborhood Hits	169	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS8_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.072411 (rank : 321)
Query Neighborhood Hits	153	Target Neighborhood Hits	145	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS8_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.076777 (rank : 298)
Query Neighborhood Hits	153	Target Neighborhood Hits	139	Shared Neighborhood Hits	25
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS9_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.081218 (rank : 289)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

BAI2_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.082539 (rank : 285)
Query Neighborhood Hits	153	Target Neighborhood Hits	332	Shared Neighborhood Hits	33
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.082618 (rank : 284)
Query Neighborhood Hits	153	Target Neighborhood Hits	323	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.095268 (rank : 239)
Query Neighborhood Hits	153	Target Neighborhood Hits	246	Shared Neighborhood Hits	32
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.099404 (rank : 231)
Query Neighborhood Hits	153	Target Neighborhood Hits	250	Shared Neighborhood Hits	35
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BMP1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.091051 (rank : 254)
Query Neighborhood Hits	153	Target Neighborhood Hits	233	Shared Neighborhood Hits	61
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.091750 (rank : 247)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BSSP4_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.061238 (rank : 408)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BSSP4_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.060272 (rank : 418)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

C1QR1_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.131347 (rank : 127)
Query Neighborhood Hits	153	Target Neighborhood Hits	493	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.130753 (rank : 130)
Query Neighborhood Hits	153	Target Neighborhood Hits	342	Shared Neighborhood Hits	76
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1RA_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.090754 (rank : 257)
Query Neighborhood Hits	153	Target Neighborhood Hits	379	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.087733 (rank : 270)
Query Neighborhood Hits	153	Target Neighborhood Hits	380	Shared Neighborhood Hits	70
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.086584 (rank : 274)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	66
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.084496 (rank : 279)
Query Neighborhood Hits	153	Target Neighborhood Hits	359	Shared Neighborhood Hits	69
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CAP7_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.053274 (rank : 503)
Query Neighborhood Hits	153	Target Neighborhood Hits	169	Shared Neighborhood Hits	21
SwissProt Accessions	P20160, P80014, Q52LG4	Gene names	AZU1
Domain Architecture
Description	Azurocidin precursor (Cationic antimicrobial protein CAP37) (Heparin- binding protein) (HBP).

CATG_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.051911 (rank : 519)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

CATG_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.051267 (rank : 524)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

CD248_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.107596 (rank : 201)
Query Neighborhood Hits	153	Target Neighborhood Hits	679	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.109415 (rank : 197)
Query Neighborhood Hits	153	Target Neighborhood Hits	578	Shared Neighborhood Hits	65
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.091634 (rank : 248)
Query Neighborhood Hits	153	Target Neighborhood Hits	353	Shared Neighborhood Hits	71
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.073492 (rank : 316)
Query Neighborhood Hits	153	Target Neighborhood Hits	295	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CELR2_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.061168 (rank : 410)
Query Neighborhood Hits	153	Target Neighborhood Hits	657	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR2_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.052756 (rank : 509)
Query Neighborhood Hits	153	Target Neighborhood Hits	584	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR3_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.058798 (rank : 433)
Query Neighborhood Hits	153	Target Neighborhood Hits	687	Shared Neighborhood Hits	80
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CFAB_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.064292 (rank : 369)
Query Neighborhood Hits	153	Target Neighborhood Hits	251	Shared Neighborhood Hits	25
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.061507 (rank : 404)
Query Neighborhood Hits	153	Target Neighborhood Hits	262	Shared Neighborhood Hits	25
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAD_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.054398 (rank : 482)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

CFAD_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.053857 (rank : 493)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

CILP2_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.062220 (rank : 394)
Query Neighborhood Hits	153	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CLC14_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.053527 (rank : 497)
Query Neighborhood Hits	153	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CLCR_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.060130 (rank : 421)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CO2_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.070098 (rank : 337)
Query Neighborhood Hits	153	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.063458 (rank : 377)
Query Neighborhood Hits	153	Target Neighborhood Hits	250	Shared Neighborhood Hits	25
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

COMP_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.095498 (rank : 238)
Query Neighborhood Hits	153	Target Neighborhood Hits	258	Shared Neighborhood Hits	61
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.100083 (rank : 228)
Query Neighborhood Hits	153	Target Neighborhood Hits	290	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.111714 (rank : 187)
Query Neighborhood Hits	153	Target Neighborhood Hits	441	Shared Neighborhood Hits	65
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.111869 (rank : 186)
Query Neighborhood Hits	153	Target Neighborhood Hits	524	Shared Neighborhood Hits	69
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.067877 (rank : 346)
Query Neighborhood Hits	153	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CS1A_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.082415 (rank : 286)
Query Neighborhood Hits	153	Target Neighborhood Hits	360	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.083968 (rank : 281)
Query Neighborhood Hits	153	Target Neighborhood Hits	361	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSMD1_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.059663 (rank : 422)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.059230 (rank : 429)
Query Neighborhood Hits	153	Target Neighborhood Hits	193	Shared Neighborhood Hits	29
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.062738 (rank : 387)
Query Neighborhood Hits	153	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.054948 (rank : 472)
Query Neighborhood Hits	153	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSPG3_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.089146 (rank : 265)
Query Neighborhood Hits	153	Target Neighborhood Hits	676	Shared Neighborhood Hits	72
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.089943 (rank : 259)
Query Neighborhood Hits	153	Target Neighborhood Hits	657	Shared Neighborhood Hits	72
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CTRB1_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.059315 (rank : 427)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CTRL_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.059434 (rank : 424)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

CUZD1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.051854 (rank : 521)
Query Neighborhood Hits	153	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.051859 (rank : 520)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DESC4_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.064428 (rank : 368)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

DLK_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.150568 (rank : 97)
Query Neighborhood Hits	153	Target Neighborhood Hits	401	Shared Neighborhood Hits	88
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DNER_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.152791 (rank : 94)
Query Neighborhood Hits	153	Target Neighborhood Hits	460	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.147041 (rank : 100)
Query Neighborhood Hits	153	Target Neighborhood Hits	413	Shared Neighborhood Hits	86
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.115445 (rank : 172)
Query Neighborhood Hits	153	Target Neighborhood Hits	292	Shared Neighborhood Hits	76
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.112288 (rank : 184)
Query Neighborhood Hits	153	Target Neighborhood Hits	317	Shared Neighborhood Hits	74
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFB2_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.050331 (rank : 541)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

EGFL7_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.115206 (rank : 173)
Query Neighborhood Hits	153	Target Neighborhood Hits	325	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.103615 (rank : 214)
Query Neighborhood Hits	153	Target Neighborhood Hits	287	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.110643 (rank : 194)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	71
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.112817 (rank : 182)
Query Neighborhood Hits	153	Target Neighborhood Hits	266	Shared Neighborhood Hits	72
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.132343 (rank : 124)
Query Neighborhood Hits	153	Target Neighborhood Hits	365	Shared Neighborhood Hits	84
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.134219 (rank : 119)
Query Neighborhood Hits	153	Target Neighborhood Hits	379	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.214725 (rank : 47)
Query Neighborhood Hits	153	Target Neighborhood Hits	343	Shared Neighborhood Hits	75
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.216380 (rank : 46)
Query Neighborhood Hits	153	Target Neighborhood Hits	358	Shared Neighborhood Hits	83
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELA1_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.055753 (rank : 466)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

ELA2A_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.057886 (rank : 442)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2A_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.059217 (rank : 430)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ELA2B_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.057524 (rank : 450)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

ELA3A_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.056331 (rank : 461)
Query Neighborhood Hits	153	Target Neighborhood Hits	173	Shared Neighborhood Hits	21
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

ELA3B_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.056803 (rank : 455)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

ELNE_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.050564 (rank : 534)
Query Neighborhood Hits	153	Target Neighborhood Hits	164	Shared Neighborhood Hits	21
SwissProt Accessions	P08246, P09649, Q6B0D9, Q6LDP5	Gene names	ELA2
Domain Architecture
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase) (PMN elastase) (Bone marrow serine protease) (Medullasin) (Human leukocyte elastase) (HLE).

ELNE_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.051011 (rank : 527)
Query Neighborhood Hits	153	Target Neighborhood Hits	167	Shared Neighborhood Hits	21
SwissProt Accessions	Q3UP87, Q61515	Gene names	Ela2
Domain Architecture	No domain graphic available
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase).

ELTD1_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.057617 (rank : 448)
Query Neighborhood Hits	153	Target Neighborhood Hits	269	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.079107 (rank : 292)
Query Neighborhood Hits	153	Target Neighborhood Hits	288	Shared Neighborhood Hits	62
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.101751 (rank : 221)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	82
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.091177 (rank : 252)
Query Neighborhood Hits	153	Target Neighborhood Hits	349	Shared Neighborhood Hits	72
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.092170 (rank : 246)
Query Neighborhood Hits	153	Target Neighborhood Hits	345	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FA10_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.102477 (rank : 219)
Query Neighborhood Hits	153	Target Neighborhood Hits	431	Shared Neighborhood Hits	89
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.104364 (rank : 210)
Query Neighborhood Hits	153	Target Neighborhood Hits	435	Shared Neighborhood Hits	92
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA11_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.062196 (rank : 395)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.062706 (rank : 388)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.100247 (rank : 227)
Query Neighborhood Hits	153	Target Neighborhood Hits	404	Shared Neighborhood Hits	89
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.096781 (rank : 236)
Query Neighborhood Hits	153	Target Neighborhood Hits	374	Shared Neighborhood Hits	87
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FBLN1_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.128539 (rank : 138)
Query Neighborhood Hits	153	Target Neighborhood Hits	324	Shared Neighborhood Hits	78
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.130896 (rank : 128)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	79
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.126889 (rank : 145)
Query Neighborhood Hits	153	Target Neighborhood Hits	392	Shared Neighborhood Hits	74
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.128878 (rank : 136)
Query Neighborhood Hits	153	Target Neighborhood Hits	505	Shared Neighborhood Hits	77
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.117677 (rank : 163)
Query Neighborhood Hits	153	Target Neighborhood Hits	293	Shared Neighborhood Hits	72
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.114215 (rank : 175)
Query Neighborhood Hits	153	Target Neighborhood Hits	279	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.117858 (rank : 161)
Query Neighborhood Hits	153	Target Neighborhood Hits	278	Shared Neighborhood Hits	75
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.117123 (rank : 165)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.121500 (rank : 155)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.118970 (rank : 158)
Query Neighborhood Hits	153	Target Neighborhood Hits	317	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.138578 (rank : 112)
Query Neighborhood Hits	153	Target Neighborhood Hits	557	Shared Neighborhood Hits	94
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.139562 (rank : 110)
Query Neighborhood Hits	153	Target Neighborhood Hits	563	Shared Neighborhood Hits	99
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.137720 (rank : 115)
Query Neighborhood Hits	153	Target Neighborhood Hits	560	Shared Neighborhood Hits	98
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.138139 (rank : 114)
Query Neighborhood Hits	153	Target Neighborhood Hits	549	Shared Neighborhood Hits	97
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.138481 (rank : 113)
Query Neighborhood Hits	153	Target Neighborhood Hits	543	Shared Neighborhood Hits	89
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FRAS1_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.073224 (rank : 317)
Query Neighborhood Hits	153	Target Neighborhood Hits	759	Shared Neighborhood Hits	80
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.070900 (rank : 329)
Query Neighborhood Hits	153	Target Neighborhood Hits	747	Shared Neighborhood Hits	72
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.130713 (rank : 132)
Query Neighborhood Hits	153	Target Neighborhood Hits	348	Shared Neighborhood Hits	81
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.132607 (rank : 123)
Query Neighborhood Hits	153	Target Neighborhood Hits	343	Shared Neighborhood Hits	77
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GLU2B_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.124976 (rank : 150)
Query Neighborhood Hits	153	Target Neighborhood Hits	377	Shared Neighborhood Hits	44
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GLU2B_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.115523 (rank : 171)
Query Neighborhood Hits	153	Target Neighborhood Hits	357	Shared Neighborhood Hits	42
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GRAH_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.050647 (rank : 533)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

GRAK_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.053384 (rank : 500)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

GRAM_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.057071 (rank : 451)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

GRN_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.128389 (rank : 140)
Query Neighborhood Hits	153	Target Neighborhood Hits	268	Shared Neighborhood Hits	59
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.107214 (rank : 203)
Query Neighborhood Hits	153	Target Neighborhood Hits	248	Shared Neighborhood Hits	53
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HABP2_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.112891 (rank : 181)
Query Neighborhood Hits	153	Target Neighborhood Hits	431	Shared Neighborhood Hits	83
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HEPS_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.062704 (rank : 389)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.063244 (rank : 380)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HGFL_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.054497 (rank : 480)
Query Neighborhood Hits	153	Target Neighborhood Hits	190	Shared Neighborhood Hits	22
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.054687 (rank : 475)
Query Neighborhood Hits	153	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGF_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.051120 (rank : 525)
Query Neighborhood Hits	153	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HGF_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.051107 (rank : 526)
Query Neighborhood Hits	153	Target Neighborhood Hits	192	Shared Neighborhood Hits	22
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HHIP_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.070054 (rank : 338)
Query Neighborhood Hits	153	Target Neighborhood Hits	249	Shared Neighborhood Hits	52
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.067689 (rank : 348)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HMCN1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.137481 (rank : 116)
Query Neighborhood Hits	153	Target Neighborhood Hits	983	Shared Neighborhood Hits	94
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HPTR_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.052991 (rank : 507)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	21
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.055303 (rank : 469)
Query Neighborhood Hits	153	Target Neighborhood Hits	184	Shared Neighborhood Hits	22
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.055369 (rank : 467)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

IDD_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.219311 (rank : 44)
Query Neighborhood Hits	153	Target Neighborhood Hits	127	Shared Neighborhood Hits	59
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.193923 (rank : 57)
Query Neighborhood Hits	153	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

ITB1_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.071060 (rank : 328)
Query Neighborhood Hits	153	Target Neighborhood Hits	298	Shared Neighborhood Hits	67
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.057887 (rank : 441)
Query Neighborhood Hits	153	Target Neighborhood Hits	283	Shared Neighborhood Hits	62
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.054006 (rank : 490)
Query Neighborhood Hits	153	Target Neighborhood Hits	326	Shared Neighborhood Hits	62
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.067040 (rank : 353)
Query Neighborhood Hits	153	Target Neighborhood Hits	325	Shared Neighborhood Hits	68
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.059502 (rank : 423)
Query Neighborhood Hits	153	Target Neighborhood Hits	319	Shared Neighborhood Hits	63
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB4_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.054503 (rank : 479)
Query Neighborhood Hits	153	Target Neighborhood Hits	458	Shared Neighborhood Hits	65
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.060748 (rank : 413)
Query Neighborhood Hits	153	Target Neighborhood Hits	310	Shared Neighborhood Hits	71
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.065639 (rank : 362)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	72
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.062787 (rank : 386)
Query Neighborhood Hits	153	Target Neighborhood Hits	318	Shared Neighborhood Hits	68
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.067441 (rank : 351)
Query Neighborhood Hits	153	Target Neighborhood Hits	341	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.058922 (rank : 431)
Query Neighborhood Hits	153	Target Neighborhood Hits	290	Shared Neighborhood Hits	66
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.067131 (rank : 352)
Query Neighborhood Hits	153	Target Neighborhood Hits	277	Shared Neighborhood Hits	67
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.051709 (rank : 522)
Query Neighborhood Hits	153	Target Neighborhood Hits	280	Shared Neighborhood Hits	65
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

JAG1_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.163324 (rank : 83)
Query Neighborhood Hits	153	Target Neighborhood Hits	518	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

K1B11_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.050067 (rank : 544)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

K1B21_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.050408 (rank : 540)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

K1B22_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.050682 (rank : 532)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1B26_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.050531 (rank : 535)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1KB1_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.052031 (rank : 516)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	23
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

K1KB3_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.050927 (rank : 528)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

K1KB5_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.050417 (rank : 539)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

K1KB9_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.050922 (rank : 529)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

KLK10_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.053300 (rank : 502)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK11_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.052406 (rank : 511)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

KLK11_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.051395 (rank : 523)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

KLK12_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.052369 (rank : 512)
Query Neighborhood Hits	153	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK13_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.054637 (rank : 477)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK14_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.054824 (rank : 473)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK15_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.053096 (rank : 505)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KLK1_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.050502 (rank : 537)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

KLK2_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.050321 (rank : 542)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

KLK4_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.053908 (rank : 492)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK5_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.053676 (rank : 496)
Query Neighborhood Hits	153	Target Neighborhood Hits	182	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK6_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.054378 (rank : 484)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK7_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.053324 (rank : 501)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK7_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.053747 (rank : 495)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK9_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.052075 (rank : 515)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLKB1_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.062109 (rank : 397)
Query Neighborhood Hits	153	Target Neighborhood Hits	183	Shared Neighborhood Hits	21
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.063065 (rank : 384)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KR101_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.077747 (rank : 296)
Query Neighborhood Hits	153	Target Neighborhood Hits	261	Shared Neighborhood Hits	51
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.074397 (rank : 309)
Query Neighborhood Hits	153	Target Neighborhood Hits	264	Shared Neighborhood Hits	50
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.105318 (rank : 207)
Query Neighborhood Hits	153	Target Neighborhood Hits	313	Shared Neighborhood Hits	58
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.057640 (rank : 447)
Query Neighborhood Hits	153	Target Neighborhood Hits	271	Shared Neighborhood Hits	46
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.108242 (rank : 199)
Query Neighborhood Hits	153	Target Neighborhood Hits	347	Shared Neighborhood Hits	66
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.113722 (rank : 178)
Query Neighborhood Hits	153	Target Neighborhood Hits	330	Shared Neighborhood Hits	64
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.066238 (rank : 359)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	43
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.077944 (rank : 295)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	52
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.070303 (rank : 334)
Query Neighborhood Hits	153	Target Neighborhood Hits	269	Shared Neighborhood Hits	50
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.067482 (rank : 350)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	42
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.055025 (rank : 471)
Query Neighborhood Hits	153	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR412_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.063061 (rank : 385)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.060173 (rank : 420)
Query Neighborhood Hits	153	Target Neighborhood Hits	199	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR511_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.068692 (rank : 343)
Query Neighborhood Hits	153	Target Neighborhood Hits	231	Shared Neighborhood Hits	37
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.054530 (rank : 478)
Query Neighborhood Hits	153	Target Neighborhood Hits	155	Shared Neighborhood Hits	29
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.054011 (rank : 489)
Query Neighborhood Hits	153	Target Neighborhood Hits	144	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA44_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.060859 (rank : 412)
Query Neighborhood Hits	153	Target Neighborhood Hits	162	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA47_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.053803 (rank : 494)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.082359 (rank : 287)
Query Neighborhood Hits	153	Target Neighborhood Hits	288	Shared Neighborhood Hits	56
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.090664 (rank : 258)
Query Neighborhood Hits	153	Target Neighborhood Hits	331	Shared Neighborhood Hits	59
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.053387 (rank : 499)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.055322 (rank : 468)
Query Neighborhood Hits	153	Target Neighborhood Hits	257	Shared Neighborhood Hits	46
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA57_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.067761 (rank : 347)
Query Neighborhood Hits	153	Target Neighborhood Hits	269	Shared Neighborhood Hits	45
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.085340 (rank : 277)
Query Neighborhood Hits	153	Target Neighborhood Hits	324	Shared Neighborhood Hits	55
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.087871 (rank : 268)
Query Neighborhood Hits	153	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.050200 (rank : 543)
Query Neighborhood Hits	153	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.050049 (rank : 545)
Query Neighborhood Hits	153	Target Neighborhood Hits	203	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.054251 (rank : 486)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.052514 (rank : 510)
Query Neighborhood Hits	153	Target Neighborhood Hits	185	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.052808 (rank : 508)
Query Neighborhood Hits	153	Target Neighborhood Hits	173	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA1_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.080286 (rank : 290)
Query Neighborhood Hits	153	Target Neighborhood Hits	804	Shared Neighborhood Hits	83
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.087496 (rank : 272)
Query Neighborhood Hits	153	Target Neighborhood Hits	838	Shared Neighborhood Hits	81
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.072533 (rank : 319)
Query Neighborhood Hits	153	Target Neighborhood Hits	1092	Shared Neighborhood Hits	80
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.073630 (rank : 315)
Query Neighborhood Hits	153	Target Neighborhood Hits	1198	Shared Neighborhood Hits	85
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.053404 (rank : 498)
Query Neighborhood Hits	153	Target Neighborhood Hits	760	Shared Neighborhood Hits	66
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA3_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.070586 (rank : 333)
Query Neighborhood Hits	153	Target Neighborhood Hits	859	Shared Neighborhood Hits	84
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.056606 (rank : 458)
Query Neighborhood Hits	153	Target Neighborhood Hits	708	Shared Neighborhood Hits	67
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.058424 (rank : 437)
Query Neighborhood Hits	153	Target Neighborhood Hits	584	Shared Neighborhood Hits	64
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.088867 (rank : 266)
Query Neighborhood Hits	153	Target Neighborhood Hits	976	Shared Neighborhood Hits	91
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.092375 (rank : 245)
Query Neighborhood Hits	153	Target Neighborhood Hits	828	Shared Neighborhood Hits	89
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.070783 (rank : 331)
Query Neighborhood Hits	153	Target Neighborhood Hits	1018	Shared Neighborhood Hits	74
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.068415 (rank : 345)
Query Neighborhood Hits	153	Target Neighborhood Hits	919	Shared Neighborhood Hits	69
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.074052 (rank : 311)
Query Neighborhood Hits	153	Target Neighborhood Hits	692	Shared Neighborhood Hits	81
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.071546 (rank : 326)
Query Neighborhood Hits	153	Target Neighborhood Hits	722	Shared Neighborhood Hits	73
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.056880 (rank : 454)
Query Neighborhood Hits	153	Target Neighborhood Hits	461	Shared Neighborhood Hits	55
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.059361 (rank : 426)
Query Neighborhood Hits	153	Target Neighborhood Hits	444	Shared Neighborhood Hits	61
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.072435 (rank : 320)
Query Neighborhood Hits	153	Target Neighborhood Hits	922	Shared Neighborhood Hits	78
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.075358 (rank : 304)
Query Neighborhood Hits	153	Target Neighborhood Hits	856	Shared Neighborhood Hits	77
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.074710 (rank : 306)
Query Neighborhood Hits	153	Target Neighborhood Hits	715	Shared Neighborhood Hits	76
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.066089 (rank : 360)
Query Neighborhood Hits	153	Target Neighborhood Hits	614	Shared Neighborhood Hits	67
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.075538 (rank : 303)
Query Neighborhood Hits	153	Target Neighborhood Hits	588	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.078840 (rank : 294)
Query Neighborhood Hits	153	Target Neighborhood Hits	624	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE3B_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.071726 (rank : 324)
Query Neighborhood Hits	153	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LTB1L_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.141725 (rank : 104)
Query Neighborhood Hits	153	Target Neighborhood Hits	553	Shared Neighborhood Hits	92
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.136028 (rank : 118)
Query Neighborhood Hits	153	Target Neighborhood Hits	502	Shared Neighborhood Hits	91
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.138981 (rank : 111)
Query Neighborhood Hits	153	Target Neighborhood Hits	552	Shared Neighborhood Hits	90
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.129455 (rank : 135)
Query Neighborhood Hits	153	Target Neighborhood Hits	617	Shared Neighborhood Hits	87
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.125707 (rank : 148)
Query Neighborhood Hits	153	Target Neighborhood Hits	502	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.127193 (rank : 143)
Query Neighborhood Hits	153	Target Neighborhood Hits	475	Shared Neighborhood Hits	90
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.136137 (rank : 117)
Query Neighborhood Hits	153	Target Neighborhood Hits	607	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LYAM2_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.057530 (rank : 449)
Query Neighborhood Hits	153	Target Neighborhood Hits	394	Shared Neighborhood Hits	64
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.061975 (rank : 398)
Query Neighborhood Hits	153	Target Neighborhood Hits	420	Shared Neighborhood Hits	66
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.062134 (rank : 396)
Query Neighborhood Hits	153	Target Neighborhood Hits	378	Shared Neighborhood Hits	64
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.063162 (rank : 382)
Query Neighborhood Hits	153	Target Neighborhood Hits	390	Shared Neighborhood Hits	67
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MASP1_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.091181 (rank : 251)
Query Neighborhood Hits	153	Target Neighborhood Hits	369	Shared Neighborhood Hits	62
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.087614 (rank : 271)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	62
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.089750 (rank : 262)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	64
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.089501 (rank : 264)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	67
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN2_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.113377 (rank : 179)
Query Neighborhood Hits	153	Target Neighborhood Hits	365	Shared Neighborhood Hits	74
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.103740 (rank : 213)
Query Neighborhood Hits	153	Target Neighborhood Hits	356	Shared Neighborhood Hits	68
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.091065 (rank : 253)
Query Neighborhood Hits	153	Target Neighborhood Hits	268	Shared Neighborhood Hits	56
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.091616 (rank : 249)
Query Neighborhood Hits	153	Target Neighborhood Hits	261	Shared Neighborhood Hits	57
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.092963 (rank : 244)
Query Neighborhood Hits	153	Target Neighborhood Hits	287	Shared Neighborhood Hits	65
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 424)	NC score	0.088213 (rank : 267)
Query Neighborhood Hits	153	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCPT1_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.051972 (rank : 518)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

MCPT2_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.050528 (rank : 536)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

MCPT4_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.050766 (rank : 530)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

MCPT6_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.058716 (rank : 434)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

MEGF8_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.105750 (rank : 206)
Query Neighborhood Hits	153	Target Neighborhood Hits	528	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.103250 (rank : 217)
Query Neighborhood Hits	153	Target Neighborhood Hits	520	Shared Neighborhood Hits	87
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.074375 (rank : 310)
Query Neighborhood Hits	153	Target Neighborhood Hits	557	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.064610 (rank : 366)
Query Neighborhood Hits	153	Target Neighborhood Hits	896	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MUC5B_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.050715 (rank : 531)
Query Neighborhood Hits	153	Target Neighborhood Hits	1020	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NAGPA_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.090769 (rank : 256)
Query Neighborhood Hits	153	Target Neighborhood Hits	282	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.079425 (rank : 291)
Query Neighborhood Hits	153	Target Neighborhood Hits	308	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.127703 (rank : 141)
Query Neighborhood Hits	153	Target Neighborhood Hits	451	Shared Neighborhood Hits	84
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.131642 (rank : 126)
Query Neighborhood Hits	153	Target Neighborhood Hits	449	Shared Neighborhood Hits	91
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.131657 (rank : 125)
Query Neighborhood Hits	153	Target Neighborhood Hits	436	Shared Neighborhood Hits	86
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NETR_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.057787 (rank : 445)
Query Neighborhood Hits	153	Target Neighborhood Hits	218	Shared Neighborhood Hits	21
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NETR_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.058701 (rank : 435)
Query Neighborhood Hits	153	Target Neighborhood Hits	216	Shared Neighborhood Hits	21
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

NFX1_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.062573 (rank : 392)
Query Neighborhood Hits	153	Target Neighborhood Hits	405	Shared Neighborhood Hits	45
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.190577 (rank : 60)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	73
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.181790 (rank : 66)
Query Neighborhood Hits	153	Target Neighborhood Hits	456	Shared Neighborhood Hits	77
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.183774 (rank : 65)
Query Neighborhood Hits	153	Target Neighborhood Hits	338	Shared Neighborhood Hits	76
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NRG4_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.060296 (rank : 417)
Query Neighborhood Hits	153	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.053197 (rank : 504)
Query Neighborhood Hits	153	Target Neighborhood Hits	79	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRPN_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.054002 (rank : 491)
Query Neighborhood Hits	153	Target Neighborhood Hits	182	Shared Neighborhood Hits	21
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

NRPN_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.052345 (rank : 513)
Query Neighborhood Hits	153	Target Neighborhood Hits	186	Shared Neighborhood Hits	22
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

NRX3A_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.052206 (rank : 514)
Query Neighborhood Hits	153	Target Neighborhood Hits	164	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NTNG1_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.066036 (rank : 361)
Query Neighborhood Hits	153	Target Neighborhood Hits	247	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.070611 (rank : 332)
Query Neighborhood Hits	153	Target Neighborhood Hits	246	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.074907 (rank : 305)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	73
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.071984 (rank : 323)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PCOC1_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.058888 (rank : 432)
Query Neighborhood Hits	153	Target Neighborhood Hits	146	Shared Neighborhood Hits	20
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.058493 (rank : 436)
Query Neighborhood Hits	153	Target Neighborhood Hits	100	Shared Neighborhood Hits	20
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.060216 (rank : 419)
Query Neighborhood Hits	153	Target Neighborhood Hits	73	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.060866 (rank : 411)
Query Neighborhood Hits	153	Target Neighborhood Hits	73	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCSK5_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.075801 (rank : 301)
Query Neighborhood Hits	153	Target Neighborhood Hits	613	Shared Neighborhood Hits	79
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PHXR5_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.052994 (rank : 506)
Query Neighborhood Hits	153	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PLMN_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.056461 (rank : 459)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.057870 (rank : 444)
Query Neighborhood Hits	153	Target Neighborhood Hits	208	Shared Neighborhood Hits	26
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

POLS2_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.064584 (rank : 367)
Query Neighborhood Hits	153	Target Neighborhood Hits	192	Shared Neighborhood Hits	22
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.063730 (rank : 374)
Query Neighborhood Hits	153	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PROC_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.096549 (rank : 237)
Query Neighborhood Hits	153	Target Neighborhood Hits	406	Shared Neighborhood Hits	88
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.104509 (rank : 208)
Query Neighborhood Hits	153	Target Neighborhood Hits	426	Shared Neighborhood Hits	93
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROS_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.130818 (rank : 129)
Query Neighborhood Hits	153	Target Neighborhood Hits	340	Shared Neighborhood Hits	79
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.125996 (rank : 146)
Query Neighborhood Hits	153	Target Neighborhood Hits	330	Shared Neighborhood Hits	77
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.130279 (rank : 133)
Query Neighborhood Hits	153	Target Neighborhood Hits	422	Shared Neighborhood Hits	91
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.117599 (rank : 164)
Query Neighborhood Hits	153	Target Neighborhood Hits	410	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRS27_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.061936 (rank : 400)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.061794 (rank : 402)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRSS8_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.061842 (rank : 401)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	22
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.062669 (rank : 390)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

RECK_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.066737 (rank : 356)
Query Neighborhood Hits	153	Target Neighborhood Hits	189	Shared Neighborhood Hits	46
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.056907 (rank : 453)
Query Neighborhood Hits	153	Target Neighborhood Hits	158	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

SCUB3_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.141261 (rank : 105)
Query Neighborhood Hits	153	Target Neighborhood Hits	428	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.140805 (rank : 107)
Query Neighborhood Hits	153	Target Neighborhood Hits	442	Shared Neighborhood Hits	90
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SEM5A_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.103219 (rank : 218)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	40
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.101132 (rank : 223)
Query Neighborhood Hits	153	Target Neighborhood Hits	162	Shared Neighborhood Hits	25
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.059288 (rank : 428)
Query Neighborhood Hits	153	Target Neighborhood Hits	289	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SLIT2_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.114860 (rank : 174)
Query Neighborhood Hits	153	Target Neighborhood Hits	708	Shared Neighborhood Hits	97
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.111188 (rank : 191)
Query Neighborhood Hits	153	Target Neighborhood Hits	684	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SMDF_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.060740 (rank : 414)
Query Neighborhood Hits	153	Target Neighborhood Hits	117	Shared Neighborhood Hits	50
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SREC2_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.116561 (rank : 167)
Query Neighborhood Hits	153	Target Neighborhood Hits	645	Shared Neighborhood Hits	82
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.113319 (rank : 180)
Query Neighborhood Hits	153	Target Neighborhood Hits	605	Shared Neighborhood Hits	82
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.122899 (rank : 152)
Query Neighborhood Hits	153	Target Neighborhood Hits	645	Shared Neighborhood Hits	97
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.108065 (rank : 200)
Query Neighborhood Hits	153	Target Neighborhood Hits	546	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.108570 (rank : 198)
Query Neighborhood Hits	153	Target Neighborhood Hits	566	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.113936 (rank : 177)
Query Neighborhood Hits	153	Target Neighborhood Hits	534	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.118475 (rank : 159)
Query Neighborhood Hits	153	Target Neighborhood Hits	528	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SUSD1_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.111599 (rank : 188)
Query Neighborhood Hits	153	Target Neighborhood Hits	285	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.062504 (rank : 393)
Query Neighborhood Hits	153	Target Neighborhood Hits	211	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.063506 (rank : 376)
Query Neighborhood Hits	153	Target Neighborhood Hits	214	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENN_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.060380 (rank : 416)
Query Neighborhood Hits	153	Target Neighborhood Hits	453	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.063095 (rank : 383)
Query Neighborhood Hits	153	Target Neighborhood Hits	484	Shared Neighborhood Hits	71
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.084125 (rank : 280)
Query Neighborhood Hits	153	Target Neighborhood Hits	526	Shared Neighborhood Hits	84
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.085567 (rank : 276)
Query Neighborhood Hits	153	Target Neighborhood Hits	531	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENX_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.126990 (rank : 144)
Query Neighborhood Hits	153	Target Neighborhood Hits	789	Shared Neighborhood Hits	99
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TEST_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.064099 (rank : 371)
Query Neighborhood Hits	153	Target Neighborhood Hits	172	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TEST_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.061646 (rank : 403)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

THRB_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.058046 (rank : 440)
Query Neighborhood Hits	153	Target Neighborhood Hits	196	Shared Neighborhood Hits	21
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.056712 (rank : 456)
Query Neighborhood Hits	153	Target Neighborhood Hits	195	Shared Neighborhood Hits	21
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THSD1_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.051977 (rank : 517)
Query Neighborhood Hits	153	Target Neighborhood Hits	153	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TLL1_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.094226 (rank : 242)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.095183 (rank : 240)
Query Neighborhood Hits	153	Target Neighborhood Hits	237	Shared Neighborhood Hits	63
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.090865 (rank : 255)
Query Neighborhood Hits	153	Target Neighborhood Hits	241	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.089937 (rank : 260)
Query Neighborhood Hits	153	Target Neighborhood Hits	240	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TM11D_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.063430 (rank : 378)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.065222 (rank : 365)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.066930 (rank : 354)
Query Neighborhood Hits	153	Target Neighborhood Hits	181	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.065472 (rank : 363)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS2_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.087815 (rank : 269)
Query Neighborhood Hits	153	Target Neighborhood Hits	252	Shared Neighborhood Hits	56
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.103501 (rank : 216)
Query Neighborhood Hits	153	Target Neighborhood Hits	243	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.093764 (rank : 243)
Query Neighborhood Hits	153	Target Neighborhood Hits	239	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS4_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.075954 (rank : 300)
Query Neighborhood Hits	153	Target Neighborhood Hits	203	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.071681 (rank : 325)
Query Neighborhood Hits	153	Target Neighborhood Hits	210	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.063886 (rank : 372)
Query Neighborhood Hits	153	Target Neighborhood Hits	181	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.063403 (rank : 379)
Query Neighborhood Hits	153	Target Neighborhood Hits	185	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPSD_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.068587 (rank : 344)
Query Neighborhood Hits	153	Target Neighborhood Hits	333	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.066772 (rank : 355)
Query Neighborhood Hits	153	Target Neighborhood Hits	334	Shared Neighborhood Hits	28
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMSP8_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.061308 (rank : 406)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TPA_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.086957 (rank : 273)
Query Neighborhood Hits	153	Target Neighborhood Hits	324	Shared Neighborhood Hits	79
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.084590 (rank : 278)
Query Neighborhood Hits	153	Target Neighborhood Hits	335	Shared Neighborhood Hits	81
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRBM_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.127221 (rank : 142)
Query Neighborhood Hits	153	Target Neighborhood Hits	339	Shared Neighborhood Hits	72
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.125517 (rank : 149)
Query Neighborhood Hits	153	Target Neighborhood Hits	361	Shared Neighborhood Hits	72
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRY1_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.054770 (rank : 474)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	22
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

TRY2_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.054436 (rank : 481)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY2_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.055062 (rank : 470)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TRY3_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.054389 (rank : 483)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TRYA1_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.057885 (rank : 443)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TRYB1_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.058094 (rank : 438)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB1_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.057739 (rank : 446)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB2_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.058094 (rank : 439)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYD_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.056606 (rank : 457)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRYG1_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.061291 (rank : 407)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.061331 (rank : 405)
Query Neighborhood Hits	153	Target Neighborhood Hits	181	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TSG6_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.054341 (rank : 485)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.054680 (rank : 476)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP3_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.097236 (rank : 234)
Query Neighborhood Hits	153	Target Neighborhood Hits	250	Shared Neighborhood Hits	65
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.099440 (rank : 230)
Query Neighborhood Hits	153	Target Neighborhood Hits	247	Shared Neighborhood Hits	66
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.112010 (rank : 185)
Query Neighborhood Hits	153	Target Neighborhood Hits	277	Shared Neighborhood Hits	70
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 542)	NC score	0.111350 (rank : 190)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP50_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.061169 (rank : 409)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

UNC5A_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.107439 (rank : 202)
Query Neighborhood Hits	153	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5A_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.120013 (rank : 157)
Query Neighborhood Hits	153	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.115939 (rank : 170)
Query Neighborhood Hits	153	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.116941 (rank : 166)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.114030 (rank : 176)
Query Neighborhood Hits	153	Target Neighborhood Hits	225	Shared Neighborhood Hits	23
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.110711 (rank : 193)
Query Neighborhood Hits	153	Target Neighborhood Hits	267	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.109918 (rank : 195)
Query Neighborhood Hits	153	Target Neighborhood Hits	268	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UROK_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.074464 (rank : 308)
Query Neighborhood Hits	153	Target Neighborhood Hits	273	Shared Neighborhood Hits	68
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROM_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.103584 (rank : 215)
Query Neighborhood Hits	153	Target Neighborhood Hits	284	Shared Neighborhood Hits	72
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.105870 (rank : 205)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	71
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.063243 (rank : 381)
Query Neighborhood Hits	153	Target Neighborhood Hits	600	Shared Neighborhood Hits	71
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.071383 (rank : 327)
Query Neighborhood Hits	153	Target Neighborhood Hits	626	Shared Neighborhood Hits	70
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VWF_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.055841 (rank : 465)
Query Neighborhood Hits	153	Target Neighborhood Hits	396	Shared Neighborhood Hits	61
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WIF1_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.130718 (rank : 131)
Query Neighborhood Hits	153	Target Neighborhood Hits	392	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.128627 (rank : 137)
Query Neighborhood Hits	153	Target Neighborhood Hits	393	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ZAN_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.056961 (rank : 452)
Query Neighborhood Hits	153	Target Neighborhood Hits	679	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.129674 (rank : 134)
Query Neighborhood Hits	153	Target Neighborhood Hits	808	Shared Neighborhood Hits	95
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

CO9_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	153	Target Neighborhood Hits	153	Shared Neighborhood Hits	153
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CO9_HUMAN
NC score	0.982218 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	153	Target Neighborhood Hits	147	Shared Neighborhood Hits	119
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO8B_HUMAN
NC score	0.835156 (rank : 3)	θ value	8.83269e-64 (rank : 6)
Query Neighborhood Hits	153	Target Neighborhood Hits	199	Shared Neighborhood Hits	110
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8A_MOUSE
NC score	0.832474 (rank : 4)	θ value	2.3998e-69 (rank : 4)
Query Neighborhood Hits	153	Target Neighborhood Hits	182	Shared Neighborhood Hits	108
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_HUMAN
NC score	0.822315 (rank : 5)	θ value	2.17053e-70 (rank : 3)
Query Neighborhood Hits	153	Target Neighborhood Hits	200	Shared Neighborhood Hits	116
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_MOUSE
NC score	0.818822 (rank : 6)	θ value	2.10232e-65 (rank : 5)
Query Neighborhood Hits	153	Target Neighborhood Hits	224	Shared Neighborhood Hits	118
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO6_HUMAN
NC score	0.740820 (rank : 7)	θ value	5.0155e-59 (rank : 7)
Query Neighborhood Hits	153	Target Neighborhood Hits	331	Shared Neighborhood Hits	121
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
NC score	0.725225 (rank : 8)	θ value	2.18062e-54 (rank : 8)
Query Neighborhood Hits	153	Target Neighborhood Hits	278	Shared Neighborhood Hits	116
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CD320_HUMAN
NC score	0.456380 (rank : 9)	θ value	0.0961366 (rank : 67)
Query Neighborhood Hits	153	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

PERF_MOUSE
NC score	0.422343 (rank : 10)	θ value	1.53129e-07 (rank : 10)
Query Neighborhood Hits	153	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

VLDLR_HUMAN
NC score	0.413808 (rank : 11)	θ value	1.38499e-08 (rank : 9)
Query Neighborhood Hits	153	Target Neighborhood Hits	383	Shared Neighborhood Hits	107
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
NC score	0.410339 (rank : 12)	θ value	5.81887e-07 (rank : 15)
Query Neighborhood Hits	153	Target Neighborhood Hits	360	Shared Neighborhood Hits	107
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP4_HUMAN
NC score	0.409663 (rank : 13)	θ value	2.21117e-06 (rank : 19)
Query Neighborhood Hits	153	Target Neighborhood Hits	355	Shared Neighborhood Hits	110
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
NC score	0.408732 (rank : 14)	θ value	4.45536e-07 (rank : 12)
Query Neighborhood Hits	153	Target Neighborhood Hits	351	Shared Neighborhood Hits	107
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LDLR_MOUSE
NC score	0.407622 (rank : 15)	θ value	2.88788e-06 (rank : 20)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	110
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP6_HUMAN
NC score	0.406735 (rank : 16)	θ value	1.43324e-05 (rank : 24)
Query Neighborhood Hits	153	Target Neighborhood Hits	235	Shared Neighborhood Hits	89
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
NC score	0.406482 (rank : 17)	θ value	1.87187e-05 (rank : 25)
Query Neighborhood Hits	153	Target Neighborhood Hits	232	Shared Neighborhood Hits	88
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LDLR_HUMAN
NC score	0.398745 (rank : 18)	θ value	9.92553e-07 (rank : 16)
Query Neighborhood Hits	153	Target Neighborhood Hits	375	Shared Neighborhood Hits	112
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP5_HUMAN
NC score	0.398400 (rank : 19)	θ value	4.1701e-05 (rank : 28)
Query Neighborhood Hits	153	Target Neighborhood Hits	224	Shared Neighborhood Hits	82
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

SORL_MOUSE
NC score	0.398130 (rank : 20)	θ value	4.45536e-07 (rank : 14)
Query Neighborhood Hits	153	Target Neighborhood Hits	439	Shared Neighborhood Hits	103
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LRP5_MOUSE
NC score	0.397017 (rank : 21)	θ value	0.000121331 (rank : 29)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	86
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

SORL_HUMAN
NC score	0.395814 (rank : 22)	θ value	4.45536e-07 (rank : 13)
Query Neighborhood Hits	153	Target Neighborhood Hits	440	Shared Neighborhood Hits	103
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

LRP2_HUMAN
NC score	0.393334 (rank : 23)	θ value	9.92553e-07 (rank : 17)
Query Neighborhood Hits	153	Target Neighborhood Hits	573	Shared Neighborhood Hits	124
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP8_HUMAN
NC score	0.389708 (rank : 24)	θ value	0.00298849 (rank : 40)
Query Neighborhood Hits	153	Target Neighborhood Hits	346	Shared Neighborhood Hits	111
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
NC score	0.389340 (rank : 25)	θ value	0.000602161 (rank : 33)
Query Neighborhood Hits	153	Target Neighborhood Hits	385	Shared Neighborhood Hits	108
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP1B_MOUSE
NC score	0.389152 (rank : 26)	θ value	1.09739e-05 (rank : 23)
Query Neighborhood Hits	153	Target Neighborhood Hits	606	Shared Neighborhood Hits	127
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_HUMAN
NC score	0.389096 (rank : 27)	θ value	4.92598e-06 (rank : 22)
Query Neighborhood Hits	153	Target Neighborhood Hits	602	Shared Neighborhood Hits	126
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
NC score	0.387794 (rank : 28)	θ value	2.88788e-06 (rank : 21)
Query Neighborhood Hits	153	Target Neighborhood Hits	617	Shared Neighborhood Hits	128
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP10_HUMAN
NC score	0.386212 (rank : 29)	θ value	0.0113563 (rank : 49)
Query Neighborhood Hits	153	Target Neighborhood Hits	197	Shared Neighborhood Hits	74
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
NC score	0.382692 (rank : 30)	θ value	0.00665767 (rank : 43)
Query Neighborhood Hits	153	Target Neighborhood Hits	169	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP3_HUMAN
NC score	0.378915 (rank : 31)	θ value	0.0113563 (rank : 50)
Query Neighborhood Hits	153	Target Neighborhood Hits	280	Shared Neighborhood Hits	85
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP12_MOUSE
NC score	0.362697 (rank : 32)	θ value	0.00134147 (rank : 36)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.360694 (rank : 33)	θ value	0.00298849 (rank : 39)
Query Neighborhood Hits	153	Target Neighborhood Hits	205	Shared Neighborhood Hits	80
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

PERF_HUMAN
NC score	0.358435 (rank : 34)	θ value	0.000786445 (rank : 34)
Query Neighborhood Hits	153	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

SSPO_MOUSE
NC score	0.340799 (rank : 35)	θ value	0.000786445 (rank : 35)
Query Neighborhood Hits	153	Target Neighborhood Hits	800	Shared Neighborhood Hits	133
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CR001_HUMAN
NC score	0.295447 (rank : 36)	θ value	0.0113563 (rank : 47)
Query Neighborhood Hits	153	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
NC score	0.293256 (rank : 37)	θ value	0.0113563 (rank : 48)
Query Neighborhood Hits	153	Target Neighborhood Hits	67	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

LRP11_MOUSE
NC score	0.281954 (rank : 38)	θ value	0.62314 (rank : 81)
Query Neighborhood Hits	153	Target Neighborhood Hits	81	Shared Neighborhood Hits	65
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

CORIN_HUMAN
NC score	0.261253 (rank : 39)	θ value	1.99992e-07 (rank : 11)
Query Neighborhood Hits	153	Target Neighborhood Hits	453	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
NC score	0.255880 (rank : 40)	θ value	1.69304e-06 (rank : 18)
Query Neighborhood Hits	153	Target Neighborhood Hits	451	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LRP11_HUMAN
NC score	0.254288 (rank : 41)	θ value	1.06291 (rank : 94)
Query Neighborhood Hits	153	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

ST14_HUMAN
NC score	0.253741 (rank : 42)	θ value	3.19293e-05 (rank : 26)
Query Neighborhood Hits	153	Target Neighborhood Hits	409	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
NC score	0.249997 (rank : 43)	θ value	3.19293e-05 (rank : 27)
Query Neighborhood Hits	153	Target Neighborhood Hits	419	Shared Neighborhood Hits	104
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

IDD_HUMAN
NC score	0.219311 (rank : 44)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	153	Target Neighborhood Hits	127	Shared Neighborhood Hits	59
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

SPIT1_HUMAN
NC score	0.217567 (rank : 45)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	153	Target Neighborhood Hits	100	Shared Neighborhood Hits	57
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

EGF_MOUSE
NC score	0.216380 (rank : 46)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	153	Target Neighborhood Hits	358	Shared Neighborhood Hits	83
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

EGF_HUMAN
NC score	0.214725 (rank : 47)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	153	Target Neighborhood Hits	343	Shared Neighborhood Hits	75
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

PGBM_MOUSE
NC score	0.211631 (rank : 48)	θ value	0.000461057 (rank : 30)
Query Neighborhood Hits	153	Target Neighborhood Hits	1073	Shared Neighborhood Hits	131
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_HUMAN
NC score	0.205497 (rank : 49)	θ value	0.00390308 (rank : 42)
Query Neighborhood Hits	153	Target Neighborhood Hits	1113	Shared Neighborhood Hits	130
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SPIT1_MOUSE
NC score	0.203345 (rank : 50)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	153	Target Neighborhood Hits	96	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

MFRP_MOUSE
NC score	0.198605 (rank : 51)	θ value	0.0330416 (rank : 57)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CFAI_HUMAN
NC score	0.197043 (rank : 52)	θ value	0.0193708 (rank : 51)
Query Neighborhood Hits	153	Target Neighborhood Hits	289	Shared Neighborhood Hits	76
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TMPS7_MOUSE
NC score	0.196388 (rank : 53)	θ value	0.0563607 (rank : 61)
Query Neighborhood Hits	153	Target Neighborhood Hits	275	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

NID1_MOUSE
NC score	0.195267 (rank : 54)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	153	Target Neighborhood Hits	335	Shared Neighborhood Hits	74
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TMPS7_HUMAN
NC score	0.194685 (rank : 55)	θ value	0.125558 (rank : 70)
Query Neighborhood Hits	153	Target Neighborhood Hits	275	Shared Neighborhood Hits	71
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TSP2_MOUSE
NC score	0.194626 (rank : 56)	θ value	0.00134147 (rank : 37)
Query Neighborhood Hits	153	Target Neighborhood Hits	352	Shared Neighborhood Hits	84
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

IDD_MOUSE
NC score	0.193923 (rank : 57)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	153	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

TSP2_HUMAN
NC score	0.192524 (rank : 58)	θ value	0.000461057 (rank : 31)
Query Neighborhood Hits	153	Target Neighborhood Hits	359	Shared Neighborhood Hits	80
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

MFRP_HUMAN
NC score	0.190884 (rank : 59)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	153	Target Neighborhood Hits	165	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NID1_HUMAN
NC score	0.190577 (rank : 60)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	73
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

CFAI_MOUSE
NC score	0.190423 (rank : 61)	θ value	0.000602161 (rank : 32)
Query Neighborhood Hits	153	Target Neighborhood Hits	290	Shared Neighborhood Hits	77
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TMPS6_HUMAN
NC score	0.189205 (rank : 62)	θ value	0.0330416 (rank : 58)
Query Neighborhood Hits	153	Target Neighborhood Hits	338	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TSP1_HUMAN
NC score	0.187214 (rank : 63)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	153	Target Neighborhood Hits	389	Shared Neighborhood Hits	86
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
NC score	0.186162 (rank : 64)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	153	Target Neighborhood Hits	396	Shared Neighborhood Hits	87
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

NID2_MOUSE
NC score	0.183774 (rank : 65)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	153	Target Neighborhood Hits	338	Shared Neighborhood Hits	76
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID2_HUMAN
NC score	0.181790 (rank : 66)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	153	Target Neighborhood Hits	456	Shared Neighborhood Hits	77
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

TMPS6_MOUSE
NC score	0.179623 (rank : 67)	θ value	0.00665767 (rank : 46)
Query Neighborhood Hits	153	Target Neighborhood Hits	341	Shared Neighborhood Hits	87
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

NETO1_HUMAN
NC score	0.175465 (rank : 68)	θ value	0.00665767 (rank : 44)
Query Neighborhood Hits	153	Target Neighborhood Hits	110	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
NC score	0.175074 (rank : 69)	θ value	0.00665767 (rank : 45)
Query Neighborhood Hits	153	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

DLL1_HUMAN
NC score	0.174022 (rank : 70)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	153	Target Neighborhood Hits	455	Shared Neighborhood Hits	103
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

NOTC1_MOUSE
NC score	0.172785 (rank : 71)	θ value	0.0736092 (rank : 64)
Query Neighborhood Hits	153	Target Neighborhood Hits	916	Shared Neighborhood Hits	104
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

JAG2_MOUSE
NC score	0.171341 (rank : 72)	θ value	0.62314 (rank : 80)
Query Neighborhood Hits	153	Target Neighborhood Hits	504	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DLL4_HUMAN
NC score	0.170366 (rank : 73)	θ value	0.125558 (rank : 69)
Query Neighborhood Hits	153	Target Neighborhood Hits	435	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL1_MOUSE
NC score	0.170206 (rank : 74)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	153	Target Neighborhood Hits	456	Shared Neighborhood Hits	99
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

NOTC2_MOUSE
NC score	0.168450 (rank : 75)	θ value	0.0736092 (rank : 66)
Query Neighborhood Hits	153	Target Neighborhood Hits	1069	Shared Neighborhood Hits	104
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

JAG2_HUMAN
NC score	0.168349 (rank : 76)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	153	Target Neighborhood Hits	491	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NOTC2_HUMAN
NC score	0.167389 (rank : 77)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	153	Target Neighborhood Hits	1113	Shared Neighborhood Hits	105
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
NC score	0.166179 (rank : 78)	θ value	0.0961366 (rank : 68)
Query Neighborhood Hits	153	Target Neighborhood Hits	906	Shared Neighborhood Hits	100
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DLL4_MOUSE
NC score	0.164751 (rank : 79)	θ value	0.62314 (rank : 79)
Query Neighborhood Hits	153	Target Neighborhood Hits	440	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

CRUM1_HUMAN
NC score	0.164714 (rank : 80)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	153	Target Neighborhood Hits	457	Shared Neighborhood Hits	96
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

JAG1_HUMAN
NC score	0.164574 (rank : 81)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	153	Target Neighborhood Hits	514	Shared Neighborhood Hits	95
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

DLL3_MOUSE
NC score	0.163835 (rank : 82)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	153	Target Neighborhood Hits	399	Shared Neighborhood Hits	90
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

JAG1_MOUSE
NC score	0.163324 (rank : 83)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	153	Target Neighborhood Hits	518	Shared Neighborhood Hits	94
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

SPON1_MOUSE
NC score	0.161882 (rank : 84)	θ value	0.00175202 (rank : 38)
Query Neighborhood Hits	153	Target Neighborhood Hits	123	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

CUBN_MOUSE
NC score	0.161146 (rank : 85)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	153	Target Neighborhood Hits	477	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

PROP_MOUSE
NC score	0.160593 (rank : 86)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	153	Target Neighborhood Hits	165	Shared Neighborhood Hits	32
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

CRUM1_MOUSE
NC score	0.160466 (rank : 87)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	153	Target Neighborhood Hits	444	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
NC score	0.159192 (rank : 88)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	153	Target Neighborhood Hits	453	Shared Neighborhood Hits	91
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DLL3_HUMAN
NC score	0.158248 (rank : 89)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	153	Target Neighborhood Hits	419	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

NOTC3_MOUSE
NC score	0.156698 (rank : 90)	θ value	0.00390308 (rank : 41)
Query Neighborhood Hits	153	Target Neighborhood Hits	975	Shared Neighborhood Hits	107
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
NC score	0.155877 (rank : 91)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	153	Target Neighborhood Hits	905	Shared Neighborhood Hits	102
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC3_HUMAN
NC score	0.155618 (rank : 92)	θ value	0.0252991 (rank : 56)
Query Neighborhood Hits	153	Target Neighborhood Hits	1062	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CUBN_HUMAN
NC score	0.154848 (rank : 93)	θ value	0.0736092 (rank : 62)
Query Neighborhood Hits	153	Target Neighborhood Hits	482	Shared Neighborhood Hits	107
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

DNER_HUMAN
NC score	0.152791 (rank : 94)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	153	Target Neighborhood Hits	460	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

NETO2_MOUSE
NC score	0.150782 (rank : 95)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	153	Target Neighborhood Hits	113	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

PROP_HUMAN
NC score	0.150722 (rank : 96)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	153	Target Neighborhood Hits	126	Shared Neighborhood Hits	31
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

DLK_HUMAN
NC score	0.150568 (rank : 97)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	153	Target Neighborhood Hits	401	Shared Neighborhood Hits	88
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

NETO2_HUMAN
NC score	0.149918 (rank : 98)	θ value	0.62314 (rank : 82)
Query Neighborhood Hits	153	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

SPON1_HUMAN
NC score	0.149527 (rank : 99)	θ value	0.0193708 (rank : 55)
Query Neighborhood Hits	153	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

DNER_MOUSE
NC score	0.147041 (rank : 100)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	153	Target Neighborhood Hits	413	Shared Neighborhood Hits	86
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

NOTC4_MOUSE
NC score	0.145873 (rank : 101)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	153	Target Neighborhood Hits	872	Shared Neighborhood Hits	101
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ENTK_HUMAN
NC score	0.145227 (rank : 102)	θ value	0.0193708 (rank : 52)
Query Neighborhood Hits	153	Target Neighborhood Hits	310	Shared Neighborhood Hits	71
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

MEGF6_HUMAN
NC score	0.143859 (rank : 103)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	153	Target Neighborhood Hits	671	Shared Neighborhood Hits	105
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LTB1L_HUMAN
NC score	0.141725 (rank : 104)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	153	Target Neighborhood Hits	553	Shared Neighborhood Hits	92
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SCUB3_HUMAN
NC score	0.141261 (rank : 105)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	153	Target Neighborhood Hits	428	Shared Neighborhood Hits	89
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

DLK_MOUSE
NC score	0.141148 (rank : 106)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	153	Target Neighborhood Hits	374	Shared Neighborhood Hits	85
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

SCUB3_MOUSE
NC score	0.140805 (rank : 107)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	153	Target Neighborhood Hits	442	Shared Neighborhood Hits	90
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LTB1L_MOUSE
NC score	0.140533 (rank : 108)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	153	Target Neighborhood Hits	514	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ENTK_MOUSE
NC score	0.139596 (rank : 109)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	153	Target Neighborhood Hits	338	Shared Neighborhood Hits	75
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

FBN1_MOUSE
NC score	0.139562 (rank : 110)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	153	Target Neighborhood Hits	563	Shared Neighborhood Hits	99
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP2_HUMAN
NC score	0.138981 (rank : 111)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	153	Target Neighborhood Hits	552	Shared Neighborhood Hits	90
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN1_HUMAN
NC score	0.138578 (rank : 112)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	153	Target Neighborhood Hits	557	Shared Neighborhood Hits	94
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN3_HUMAN
NC score	0.138481 (rank : 113)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	153	Target Neighborhood Hits	543	Shared Neighborhood Hits	89
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN2_MOUSE
NC score	0.138139 (rank : 114)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	153	Target Neighborhood Hits	549	Shared Neighborhood Hits	97
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
NC score	0.137720 (rank : 115)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	153	Target Neighborhood Hits	560	Shared Neighborhood Hits	98
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

HMCN1_HUMAN
NC score	0.137481 (rank : 116)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	153	Target Neighborhood Hits	983	Shared Neighborhood Hits	94
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LTBP4_MOUSE
NC score	0.136137 (rank : 117)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	153	Target Neighborhood Hits	607	Shared Neighborhood Hits	92
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTB1S_HUMAN
NC score	0.136028 (rank : 118)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	153	Target Neighborhood Hits	502	Shared Neighborhood Hits	91
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

EGFL9_MOUSE
NC score	0.134219 (rank : 119)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	153	Target Neighborhood Hits	379	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

LTB1S_MOUSE
NC score	0.134086 (rank : 120)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	153	Target Neighborhood Hits	479	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TENA_MOUSE
NC score	0.134004 (rank : 121)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	153	Target Neighborhood Hits	596	Shared Neighborhood Hits	98
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENA_HUMAN
NC score	0.133881 (rank : 122)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	153	Target Neighborhood Hits	631	Shared Neighborhood Hits	95
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

GAS6_MOUSE
NC score	0.132607 (rank : 123)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	153	Target Neighborhood Hits	343	Shared Neighborhood Hits	77
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

EGFL9_HUMAN
NC score	0.132343 (rank : 124)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	153	Target Neighborhood Hits	365	Shared Neighborhood Hits	84
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

NELL2_MOUSE
NC score	0.131657 (rank : 125)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	153	Target Neighborhood Hits	436	Shared Neighborhood Hits	86
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NELL2_HUMAN
NC score	0.131642 (rank : 126)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	153	Target Neighborhood Hits	449	Shared Neighborhood Hits	91
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

C1QR1_HUMAN
NC score	0.131347 (rank : 127)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	153	Target Neighborhood Hits	493	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

FBLN1_MOUSE
NC score	0.130896 (rank : 128)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	79
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

PROS_HUMAN
NC score	0.130818 (rank : 129)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	153	Target Neighborhood Hits	340	Shared Neighborhood Hits	79
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

C1QR1_MOUSE
NC score	0.130753 (rank : 130)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	153	Target Neighborhood Hits	342	Shared Neighborhood Hits	76
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

WIF1_HUMAN
NC score	0.130718 (rank : 131)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	153	Target Neighborhood Hits	392	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

GAS6_HUMAN
NC score	0.130713 (rank : 132)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	153	Target Neighborhood Hits	348	Shared Neighborhood Hits	81
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

PROZ_HUMAN
NC score	0.130279 (rank : 133)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	153	Target Neighborhood Hits	422	Shared Neighborhood Hits	91
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

ZAN_MOUSE
NC score	0.129674 (rank : 134)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	153	Target Neighborhood Hits	808	Shared Neighborhood Hits	95
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LTBP2_MOUSE
NC score	0.129455 (rank : 135)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	153	Target Neighborhood Hits	617	Shared Neighborhood Hits	87
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBLN2_MOUSE
NC score	0.128878 (rank : 136)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	153	Target Neighborhood Hits	505	Shared Neighborhood Hits	77
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

WIF1_MOUSE
NC score	0.128627 (rank : 137)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	153	Target Neighborhood Hits	393	Shared Neighborhood Hits	75
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

FBLN1_HUMAN
NC score	0.128539 (rank : 138)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	153	Target Neighborhood Hits	324	Shared Neighborhood Hits	78
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

AGRIN_HUMAN
NC score	0.128401 (rank : 139)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	153	Target Neighborhood Hits	582	Shared Neighborhood Hits	91
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

GRN_HUMAN
NC score	0.128389 (rank : 140)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	153	Target Neighborhood Hits	268	Shared Neighborhood Hits	59
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

NELL1_HUMAN
NC score	0.127703 (rank : 141)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	153	Target Neighborhood Hits	451	Shared Neighborhood Hits	84
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

TRBM_HUMAN
NC score	0.127221 (rank : 142)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	153	Target Neighborhood Hits	339	Shared Neighborhood Hits	72
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LTBP3_MOUSE
NC score	0.127193 (rank : 143)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	153	Target Neighborhood Hits	475	Shared Neighborhood Hits	90
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TENX_HUMAN
NC score	0.126990 (rank : 144)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	153	Target Neighborhood Hits	789	Shared Neighborhood Hits	99
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

FBLN2_HUMAN
NC score	0.126889 (rank : 145)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	153	Target Neighborhood Hits	392	Shared Neighborhood Hits	74
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

PROS_MOUSE
NC score	0.125996 (rank : 146)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	153	Target Neighborhood Hits	330	Shared Neighborhood Hits	77
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

HABP2_MOUSE
NC score	0.125921 (rank : 147)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	153	Target Neighborhood Hits	445	Shared Neighborhood Hits	95
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LTBP3_HUMAN
NC score	0.125707 (rank : 148)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	153	Target Neighborhood Hits	502	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TRBM_MOUSE
NC score	0.125517 (rank : 149)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	153	Target Neighborhood Hits	361	Shared Neighborhood Hits	72
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

GLU2B_HUMAN
NC score	0.124976 (rank : 150)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	153	Target Neighborhood Hits	377	Shared Neighborhood Hits	44
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

SPON2_MOUSE
NC score	0.124064 (rank : 151)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	153	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

SREC_HUMAN
NC score	0.122899 (rank : 152)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	153	Target Neighborhood Hits	645	Shared Neighborhood Hits	97
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

TMPS9_HUMAN
NC score	0.122674 (rank : 153)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

SLIT1_MOUSE
NC score	0.122368 (rank : 154)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	153	Target Neighborhood Hits	715	Shared Neighborhood Hits	100
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

FBLN5_HUMAN
NC score	0.121500 (rank : 155)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

TMPS9_MOUSE
NC score	0.120881 (rank : 156)	θ value	0.0431538 (rank : 60)
Query Neighborhood Hits	153	Target Neighborhood Hits	296	Shared Neighborhood Hits	62
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

UNC5A_MOUSE
NC score	0.120013 (rank : 157)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	153	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

FBLN5_MOUSE
NC score	0.118970 (rank : 158)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	153	Target Neighborhood Hits	317	Shared Neighborhood Hits	73
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

STAB2_MOUSE
NC score	0.118475 (rank : 159)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	153	Target Neighborhood Hits	528	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SLIT1_HUMAN
NC score	0.118006 (rank : 160)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	153	Target Neighborhood Hits	700	Shared Neighborhood Hits	95
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

FBLN4_HUMAN
NC score	0.117858 (rank : 161)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	153	Target Neighborhood Hits	278	Shared Neighborhood Hits	75
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

RXFP2_HUMAN
NC score	0.117705 (rank : 162)	θ value	0.0193708 (rank : 54)
Query Neighborhood Hits	153	Target Neighborhood Hits	736	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

FBLN3_HUMAN
NC score	0.117677 (rank : 163)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	153	Target Neighborhood Hits	293	Shared Neighborhood Hits	72
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

PROZ_MOUSE
NC score	0.117599 (rank : 164)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	153	Target Neighborhood Hits	410	Shared Neighborhood Hits	87
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FBLN4_MOUSE
NC score	0.117123 (rank : 165)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

UNC5B_MOUSE
NC score	0.116941 (rank : 166)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

SREC2_HUMAN
NC score	0.116561 (rank : 167)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	153	Target Neighborhood Hits	645	Shared Neighborhood Hits	82
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SLIT3_HUMAN
NC score	0.116153 (rank : 168)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	153	Target Neighborhood Hits	682	Shared Neighborhood Hits	94
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

UNC5C_HUMAN
NC score	0.116126 (rank : 169)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	25
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5B_HUMAN
NC score	0.115939 (rank : 170)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	153	Target Neighborhood Hits	225	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

GLU2B_MOUSE
NC score	0.115523 (rank : 171)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	153	Target Neighborhood Hits	357	Shared Neighborhood Hits	42
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

EDIL3_HUMAN
NC score	0.115445 (rank : 172)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	153	Target Neighborhood Hits	292	Shared Neighborhood Hits	76
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
NC score	0.115206 (rank : 173)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	153	Target Neighborhood Hits	325	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

SLIT2_HUMAN
NC score	0.114860 (rank : 174)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	153	Target Neighborhood Hits	708	Shared Neighborhood Hits	97
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

FBLN3_MOUSE
NC score	0.114215 (rank : 175)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	153	Target Neighborhood Hits	279	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

UNC5C_MOUSE
NC score	0.114030 (rank : 176)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	153	Target Neighborhood Hits	225	Shared Neighborhood Hits	23
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

STAB2_HUMAN
NC score	0.113936 (rank : 177)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	153	Target Neighborhood Hits	534	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

KR107_HUMAN
NC score	0.113722 (rank : 178)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	153	Target Neighborhood Hits	330	Shared Neighborhood Hits	64
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

MATN2_HUMAN
NC score	0.113377 (rank : 179)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	153	Target Neighborhood Hits	365	Shared Neighborhood Hits	74
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

SREC2_MOUSE
NC score	0.113319 (rank : 180)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	153	Target Neighborhood Hits	605	Shared Neighborhood Hits	82
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

HABP2_HUMAN
NC score	0.112891 (rank : 181)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	153	Target Neighborhood Hits	431	Shared Neighborhood Hits	83
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

EGFL8_MOUSE
NC score	0.112817 (rank : 182)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	153	Target Neighborhood Hits	266	Shared Neighborhood Hits	72
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

FA9_HUMAN
NC score	0.112335 (rank : 183)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	153	Target Neighborhood Hits	421	Shared Neighborhood Hits	97
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

EDIL3_MOUSE
NC score	0.112288 (rank : 184)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	153	Target Neighborhood Hits	317	Shared Neighborhood Hits	74
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

TSP4_HUMAN
NC score	0.112010 (rank : 185)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	153	Target Neighborhood Hits	277	Shared Neighborhood Hits	70
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

CREL1_MOUSE
NC score	0.111869 (rank : 186)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	153	Target Neighborhood Hits	524	Shared Neighborhood Hits	69
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_HUMAN
NC score	0.111714 (rank : 187)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	153	Target Neighborhood Hits	441	Shared Neighborhood Hits	65
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

SUSD1_HUMAN
NC score	0.111599 (rank : 188)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	153	Target Neighborhood Hits	285	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

HGFA_HUMAN
NC score	0.111380 (rank : 189)	θ value	0.0736092 (rank : 63)
Query Neighborhood Hits	153	Target Neighborhood Hits	436	Shared Neighborhood Hits	87
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TSP4_MOUSE
NC score	0.111350 (rank : 190)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

SLIT2_MOUSE
NC score	0.111188 (rank : 191)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	153	Target Neighborhood Hits	684	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

HGFA_MOUSE
NC score	0.110845 (rank : 192)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	153	Target Neighborhood Hits	419	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

UNC5D_HUMAN
NC score	0.110711 (rank : 193)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	153	Target Neighborhood Hits	267	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

EGFL8_HUMAN
NC score	0.110643 (rank : 194)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	71
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

UNC5D_MOUSE
NC score	0.109918 (rank : 195)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	153	Target Neighborhood Hits	268	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

SLIT3_MOUSE
NC score	0.109515 (rank : 196)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	153	Target Neighborhood Hits	700	Shared Neighborhood Hits	89
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

CD248_MOUSE
NC score	0.109415 (rank : 197)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	153	Target Neighborhood Hits	578	Shared Neighborhood Hits	65
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

STAB1_MOUSE
NC score	0.108570 (rank : 198)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	153	Target Neighborhood Hits	566	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

KR106_HUMAN
NC score	0.108242 (rank : 199)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	153	Target Neighborhood Hits	347	Shared Neighborhood Hits	66
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

STAB1_HUMAN
NC score	0.108065 (rank : 200)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	153	Target Neighborhood Hits	546	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

CD248_HUMAN
NC score	0.107596 (rank : 201)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	153	Target Neighborhood Hits	679	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

UNC5A_HUMAN
NC score	0.107439 (rank : 202)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	153	Target Neighborhood Hits	198	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

GRN_MOUSE
NC score	0.107214 (rank : 203)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	153	Target Neighborhood Hits	248	Shared Neighborhood Hits	53
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

FA12_HUMAN
NC score	0.106124 (rank : 204)	θ value	0.0431538 (rank : 59)
Query Neighborhood Hits	153	Target Neighborhood Hits	425	Shared Neighborhood Hits	79
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

UROM_MOUSE
NC score	0.105870 (rank : 205)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	71
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

MEGF8_HUMAN
NC score	0.105750 (rank : 206)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	153	Target Neighborhood Hits	528	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KR104_HUMAN
NC score	0.105318 (rank : 207)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	153	Target Neighborhood Hits	313	Shared Neighborhood Hits	58
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

PROC_MOUSE
NC score	0.104509 (rank : 208)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	153	Target Neighborhood Hits	426	Shared Neighborhood Hits	93
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TMPS3_HUMAN
NC score	0.104431 (rank : 209)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	153	Target Neighborhood Hits	245	Shared Neighborhood Hits	64
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

FA10_MOUSE
NC score	0.104364 (rank : 210)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	153	Target Neighborhood Hits	435	Shared Neighborhood Hits	92
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

SEM5B_MOUSE
NC score	0.104025 (rank : 211)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	153	Target Neighborhood Hits	190	Shared Neighborhood Hits	38
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SPON2_HUMAN
NC score	0.103895 (rank : 212)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	153	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

MATN2_MOUSE
NC score	0.103740 (rank : 213)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	153	Target Neighborhood Hits	356	Shared Neighborhood Hits	68
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

EGFL7_MOUSE
NC score	0.103615 (rank : 214)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	153	Target Neighborhood Hits	287	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

UROM_HUMAN
NC score	0.103584 (rank : 215)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	153	Target Neighborhood Hits	284	Shared Neighborhood Hits	72
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

TMPS2_MOUSE
NC score	0.103501 (rank : 216)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	153	Target Neighborhood Hits	243	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

MEGF8_MOUSE
NC score	0.103250 (rank : 217)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	153	Target Neighborhood Hits	520	Shared Neighborhood Hits	87
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SEM5A_HUMAN
NC score	0.103219 (rank : 218)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	40
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

FA10_HUMAN
NC score	0.102477 (rank : 219)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	153	Target Neighborhood Hits	431	Shared Neighborhood Hits	89
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

RXFP2_MOUSE
NC score	0.102232 (rank : 220)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	153	Target Neighborhood Hits	760	Shared Neighborhood Hits	62
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

EMR1_HUMAN
NC score	0.101751 (rank : 221)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	82
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

SEM5B_HUMAN
NC score	0.101273 (rank : 222)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5A_MOUSE
NC score	0.101132 (rank : 223)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	153	Target Neighborhood Hits	162	Shared Neighborhood Hits	25
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

CSPG2_MOUSE
NC score	0.100889 (rank : 224)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	153	Target Neighborhood Hits	711	Shared Neighborhood Hits	79
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

BAI1_HUMAN
NC score	0.100797 (rank : 225)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	153	Target Neighborhood Hits	375	Shared Neighborhood Hits	38
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CSPG2_HUMAN
NC score	0.100766 (rank : 226)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	153	Target Neighborhood Hits	681	Shared Neighborhood Hits	78
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

FA7_HUMAN
NC score	0.100247 (rank : 227)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	153	Target Neighborhood Hits	404	Shared Neighborhood Hits	89
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

COMP_MOUSE
NC score	0.100083 (rank : 228)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	153	Target Neighborhood Hits	290	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TDGF1_MOUSE
NC score	0.099904 (rank : 229)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	153	Target Neighborhood Hits	146	Shared Neighborhood Hits	62
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TSP3_MOUSE
NC score	0.099440 (rank : 230)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	153	Target Neighborhood Hits	247	Shared Neighborhood Hits	66
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

BAI3_MOUSE
NC score	0.099404 (rank : 231)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	153	Target Neighborhood Hits	250	Shared Neighborhood Hits	35
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CFC1_HUMAN
NC score	0.098455 (rank : 232)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	153	Target Neighborhood Hits	148	Shared Neighborhood Hits	64
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

BAI1_MOUSE
NC score	0.097959 (rank : 233)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	153	Target Neighborhood Hits	340	Shared Neighborhood Hits	32
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

TSP3_HUMAN
NC score	0.097236 (rank : 234)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	153	Target Neighborhood Hits	250	Shared Neighborhood Hits	65
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

CFC1_MOUSE
NC score	0.097034 (rank : 235)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	153	Target Neighborhood Hits	125	Shared Neighborhood Hits	62
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

FA7_MOUSE
NC score	0.096781 (rank : 236)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	153	Target Neighborhood Hits	374	Shared Neighborhood Hits	87
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

PROC_HUMAN
NC score	0.096549 (rank : 237)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	153	Target Neighborhood Hits	406	Shared Neighborhood Hits	88
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

COMP_HUMAN
NC score	0.095498 (rank : 238)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	153	Target Neighborhood Hits	258	Shared Neighborhood Hits	61
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

BAI3_HUMAN
NC score	0.095268 (rank : 239)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	153	Target Neighborhood Hits	246	Shared Neighborhood Hits	32
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

TLL1_MOUSE
NC score	0.095183 (rank : 240)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	153	Target Neighborhood Hits	237	Shared Neighborhood Hits	63
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

RXFP1_HUMAN
NC score	0.095038 (rank : 241)	θ value	0.0193708 (rank : 53)
Query Neighborhood Hits	153	Target Neighborhood Hits	816	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HBX9	Gene names	RXFP1, LGR7
Domain Architecture
Description	Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-rich repeat-containing G-protein coupled receptor 7).

TLL1_HUMAN
NC score	0.094226 (rank : 242)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TMPS3_MOUSE
NC score	0.093764 (rank : 243)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	153	Target Neighborhood Hits	239	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

MATN4_HUMAN
NC score	0.092963 (rank : 244)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	153	Target Neighborhood Hits	287	Shared Neighborhood Hits	65
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

LAMA5_MOUSE
NC score	0.092375 (rank : 245)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	153	Target Neighborhood Hits	828	Shared Neighborhood Hits	89
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

EMR2_HUMAN
NC score	0.092170 (rank : 246)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	153	Target Neighborhood Hits	345	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

BMP1_MOUSE
NC score	0.091750 (rank : 247)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	153	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CD97_HUMAN
NC score	0.091634 (rank : 248)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	153	Target Neighborhood Hits	353	Shared Neighborhood Hits	71
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

MATN3_MOUSE
NC score	0.091616 (rank : 249)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	153	Target Neighborhood Hits	261	Shared Neighborhood Hits	57
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

TDGF2_HUMAN
NC score	0.091286 (rank : 250)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	153	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

MASP1_HUMAN
NC score	0.091181 (rank : 251)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	153	Target Neighborhood Hits	369	Shared Neighborhood Hits	62
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

EMR1_MOUSE
NC score	0.091177 (rank : 252)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	153	Target Neighborhood Hits	349	Shared Neighborhood Hits	72
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

MATN3_HUMAN
NC score	0.091065 (rank : 253)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	153	Target Neighborhood Hits	268	Shared Neighborhood Hits	56
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

BMP1_HUMAN
NC score	0.091051 (rank : 254)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	153	Target Neighborhood Hits	233	Shared Neighborhood Hits	61
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_HUMAN
NC score	0.090865 (rank : 255)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	153	Target Neighborhood Hits	241	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

NAGPA_HUMAN
NC score	0.090769 (rank : 256)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	153	Target Neighborhood Hits	282	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

C1RA_MOUSE
NC score	0.090754 (rank : 257)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	153	Target Neighborhood Hits	379	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

KRA53_HUMAN
NC score	0.090664 (rank : 258)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	153	Target Neighborhood Hits	331	Shared Neighborhood Hits	59
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

CSPG3_MOUSE
NC score	0.089943 (rank : 259)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	153	Target Neighborhood Hits	657	Shared Neighborhood Hits	72
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TLL2_MOUSE
NC score	0.089937 (rank : 260)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	153	Target Neighborhood Hits	240	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

FATH_HUMAN
NC score	0.089916 (rank : 261)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	153	Target Neighborhood Hits	570	Shared Neighborhood Hits	87
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

MASP2_HUMAN
NC score	0.089750 (rank : 262)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	64
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

ATS13_HUMAN
NC score	0.089637 (rank : 263)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	153	Target Neighborhood Hits	238	Shared Neighborhood Hits	26
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

MASP2_MOUSE
NC score	0.089501 (rank : 264)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	67
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CSPG3_HUMAN
NC score	0.089146 (rank : 265)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	153	Target Neighborhood Hits	676	Shared Neighborhood Hits	72
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LAMA5_HUMAN
NC score	0.088867 (rank : 266)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	153	Target Neighborhood Hits	976	Shared Neighborhood Hits	91
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MATN4_MOUSE
NC score	0.088213 (rank : 267)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	153	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

KRA59_HUMAN
NC score	0.087871 (rank : 268)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	153	Target Neighborhood Hits	310	Shared Neighborhood Hits	51
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

TMPS2_HUMAN
NC score	0.087815 (rank : 269)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	153	Target Neighborhood Hits	252	Shared Neighborhood Hits	56
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

C1RB_MOUSE
NC score	0.087733 (rank : 270)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	153	Target Neighborhood Hits	380	Shared Neighborhood Hits	70
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

MASP1_MOUSE
NC score	0.087614 (rank : 271)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	62
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

LAMA1_MOUSE
NC score	0.087496 (rank : 272)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	153	Target Neighborhood Hits	838	Shared Neighborhood Hits	81
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

TPA_HUMAN
NC score	0.086957 (rank : 273)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	153	Target Neighborhood Hits	324	Shared Neighborhood Hits	79
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

C1R_HUMAN
NC score	0.086584 (rank : 274)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	153	Target Neighborhood Hits	364	Shared Neighborhood Hits	66
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

TDGF1_HUMAN
NC score	0.086222 (rank : 275)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	153	Target Neighborhood Hits	132	Shared Neighborhood Hits	59
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TENR_MOUSE
NC score	0.085567 (rank : 276)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	153	Target Neighborhood Hits	531	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

KRA58_HUMAN
NC score	0.085340 (rank : 277)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	153	Target Neighborhood Hits	324	Shared Neighborhood Hits	55
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

TPA_MOUSE
NC score	0.084590 (rank : 278)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	153	Target Neighborhood Hits	335	Shared Neighborhood Hits	81
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

C1S_HUMAN
NC score	0.084496 (rank : 279)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	153	Target Neighborhood Hits	359	Shared Neighborhood Hits	69
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

TENR_HUMAN
NC score	0.084125 (rank : 280)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	153	Target Neighborhood Hits	526	Shared Neighborhood Hits	84
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

CS1B_MOUSE
NC score	0.083968 (rank : 281)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	153	Target Neighborhood Hits	361	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MFGM_MOUSE
NC score	0.083207 (rank : 282)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	153	Target Neighborhood Hits	233	Shared Neighborhood Hits	66
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

ATRN_HUMAN
NC score	0.082827 (rank : 283)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	153	Target Neighborhood Hits	525	Shared Neighborhood Hits	87
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

BAI2_MOUSE
NC score	0.082618 (rank : 284)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	153	Target Neighborhood Hits	323	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
NC score	0.082539 (rank : 285)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	153	Target Neighborhood Hits	332	Shared Neighborhood Hits	33
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CS1A_MOUSE
NC score	0.082415 (rank : 286)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	153	Target Neighborhood Hits	360	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

KRA51_HUMAN
NC score	0.082359 (rank : 287)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	153	Target Neighborhood Hits	288	Shared Neighborhood Hits	56
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

ATS13_MOUSE
NC score	0.082273 (rank : 288)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	153	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS9_HUMAN
NC score	0.081218 (rank : 289)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	44
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

LAMA1_HUMAN
NC score	0.080286 (rank : 290)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	153	Target Neighborhood Hits	804	Shared Neighborhood Hits	83
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NAGPA_MOUSE
NC score	0.079425 (rank : 291)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	153	Target Neighborhood Hits	308	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

ELTD1_MOUSE
NC score	0.079107 (rank : 292)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	153	Target Neighborhood Hits	288	Shared Neighborhood Hits	62
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ATRN_MOUSE
NC score	0.078852 (rank : 293)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	153	Target Neighborhood Hits	519	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

LAMC3_MOUSE
NC score	0.078840 (rank : 294)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	153	Target Neighborhood Hits	624	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

KR109_HUMAN
NC score	0.077944 (rank : 295)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	52
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR101_HUMAN
NC score	0.077747 (rank : 296)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	153	Target Neighborhood Hits	261	Shared Neighborhood Hits	51
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

UROK_HUMAN
NC score	0.076889 (rank : 297)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	153	Target Neighborhood Hits	272	Shared Neighborhood Hits	73
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ATS8_MOUSE
NC score	0.076777 (rank : 298)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	153	Target Neighborhood Hits	139	Shared Neighborhood Hits	25
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS20_MOUSE
NC score	0.076206 (rank : 299)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	153	Target Neighborhood Hits	225	Shared Neighborhood Hits	38
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

TMPS4_HUMAN
NC score	0.075954 (rank : 300)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	153	Target Neighborhood Hits	203	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

PCSK5_MOUSE
NC score	0.075801 (rank : 301)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	153	Target Neighborhood Hits	613	Shared Neighborhood Hits	79
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

ATS16_HUMAN
NC score	0.075778 (rank : 302)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	153	Target Neighborhood Hits	208	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

LAMC3_HUMAN
NC score	0.075538 (rank : 303)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	153	Target Neighborhood Hits	588	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC1_MOUSE
NC score	0.075358 (rank : 304)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	153	Target Neighborhood Hits	856	Shared Neighborhood Hits	77
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NTNG2_HUMAN
NC score	0.074907 (rank : 305)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	73
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMC2_HUMAN
NC score	0.074710 (rank : 306)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	153	Target Neighborhood Hits	715	Shared Neighborhood Hits	76
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

ATS6_HUMAN
NC score	0.074593 (rank : 307)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	153	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

UROK_MOUSE
NC score	0.074464 (rank : 308)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	153	Target Neighborhood Hits	273	Shared Neighborhood Hits	68
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

KR102_HUMAN
NC score	0.074397 (rank : 309)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	153	Target Neighborhood Hits	264	Shared Neighborhood Hits	50
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

MEGF9_HUMAN
NC score	0.074375 (rank : 310)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	153	Target Neighborhood Hits	557	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMB2_HUMAN
NC score	0.074052 (rank : 311)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	153	Target Neighborhood Hits	692	Shared Neighborhood Hits	81
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

ATS18_MOUSE
NC score	0.073764 (rank : 312)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	153	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

MMRN1_HUMAN
NC score	0.073685 (rank : 313)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	153	Target Neighborhood Hits	636	Shared Neighborhood Hits	61
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

ATS18_HUMAN
NC score	0.073682 (rank : 314)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	153	Target Neighborhood Hits	169	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

LAMA2_MOUSE
NC score	0.073630 (rank : 315)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	153	Target Neighborhood Hits	1198	Shared Neighborhood Hits	85
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CD97_MOUSE
NC score	0.073492 (rank : 316)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	153	Target Neighborhood Hits	295	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

FRAS1_HUMAN
NC score	0.073224 (rank : 317)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	153	Target Neighborhood Hits	759	Shared Neighborhood Hits	80
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ATS2_HUMAN
NC score	0.072563 (rank : 318)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	25
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

LAMA2_HUMAN
NC score	0.072533 (rank : 319)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	153	Target Neighborhood Hits	1092	Shared Neighborhood Hits	80
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC1_HUMAN
NC score	0.072435 (rank : 320)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	153	Target Neighborhood Hits	922	Shared Neighborhood Hits	78
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ATS8_HUMAN
NC score	0.072411 (rank : 321)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	153	Target Neighborhood Hits	145	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS20_HUMAN
NC score	0.072304 (rank : 322)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	153	Target Neighborhood Hits	192	Shared Neighborhood Hits	35
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

NTNG2_MOUSE
NC score	0.071984 (rank : 323)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	153	Target Neighborhood Hits	276	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LCE3B_HUMAN
NC score	0.071726 (rank : 324)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	153	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

TMPS4_MOUSE
NC score	0.071681 (rank : 325)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	153	Target Neighborhood Hits	210	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

LAMB2_MOUSE
NC score	0.071546 (rank : 326)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	153	Target Neighborhood Hits	722	Shared Neighborhood Hits	73
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

USH2A_MOUSE
NC score	0.071383 (rank : 327)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	153	Target Neighborhood Hits	626	Shared Neighborhood Hits	70
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ITB1_HUMAN
NC score	0.071060 (rank : 328)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	153	Target Neighborhood Hits	298	Shared Neighborhood Hits	67
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

FRAS1_MOUSE
NC score	0.070900 (rank : 329)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	153	Target Neighborhood Hits	747	Shared Neighborhood Hits	72
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ATS16_MOUSE
NC score	0.070841 (rank : 330)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	25
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

LAMB1_HUMAN
NC score	0.070783 (rank : 331)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	153	Target Neighborhood Hits	1018	Shared Neighborhood Hits	74
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NTNG1_MOUSE
NC score	0.070611 (rank : 332)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	153	Target Neighborhood Hits	246	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMA3_MOUSE
NC score	0.070586 (rank : 333)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	153	Target Neighborhood Hits	859	Shared Neighborhood Hits	84
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

KR10B_HUMAN
NC score	0.070303 (rank : 334)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	153	Target Neighborhood Hits	269	Shared Neighborhood Hits	50
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

ATS3_HUMAN
NC score	0.070256 (rank : 335)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	26
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS12_MOUSE
NC score	0.070243 (rank : 336)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	153	Target Neighborhood Hits	220	Shared Neighborhood Hits	24
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

CO2_HUMAN
NC score	0.070098 (rank : 337)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	153	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

HHIP_HUMAN
NC score	0.070054 (rank : 338)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	153	Target Neighborhood Hits	249	Shared Neighborhood Hits	52
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ATS1_HUMAN
NC score	0.069948 (rank : 339)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	153	Target Neighborhood Hits	159	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS1_MOUSE
NC score	0.069690 (rank : 340)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	153	Target Neighborhood Hits	158	Shared Neighborhood Hits	25
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS2_MOUSE
NC score	0.069661 (rank : 341)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS17_HUMAN
NC score	0.068953 (rank : 342)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	153	Target Neighborhood Hits	194	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

KR511_HUMAN
NC score	0.068692 (rank : 343)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	153	Target Neighborhood Hits	231	Shared Neighborhood Hits	37
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

TMPSD_HUMAN
NC score	0.068587 (rank : 344)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	153	Target Neighborhood Hits	333	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

LAMB1_MOUSE
NC score	0.068415 (rank : 345)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	153	Target Neighborhood Hits	919	Shared Neighborhood Hits	69
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

CRIM1_HUMAN
NC score	0.067877 (rank : 346)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	153	Target Neighborhood Hits	362	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KRA57_HUMAN
NC score	0.067761 (rank : 347)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	153	Target Neighborhood Hits	269	Shared Neighborhood Hits	45
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

HHIP_MOUSE
NC score	0.067689 (rank : 348)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	51
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ATS12_HUMAN
NC score	0.067523 (rank : 349)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	153	Target Neighborhood Hits	251	Shared Neighborhood Hits	23
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

KR10C_HUMAN
NC score	0.067482 (rank : 350)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	153	Target Neighborhood Hits	219	Shared Neighborhood Hits	42
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

ITB6_MOUSE
NC score	0.067441 (rank : 351)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	153	Target Neighborhood Hits	341	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_MOUSE
NC score	0.067131 (rank : 352)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	153	Target Neighborhood Hits	277	Shared Neighborhood Hits	67
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB3_HUMAN
NC score	0.067040 (rank : 353)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	153	Target Neighborhood Hits	325	Shared Neighborhood Hits	68
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

TM11E_HUMAN
NC score	0.066930 (rank : 354)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	153	Target Neighborhood Hits	181	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPSD_MOUSE
NC score	0.066772 (rank : 355)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	153	Target Neighborhood Hits	334	Shared Neighborhood Hits	28
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

RECK_HUMAN
NC score	0.066737 (rank : 356)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	153	Target Neighborhood Hits	189	Shared Neighborhood Hits	46
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

ATS5_MOUSE
NC score	0.066503 (rank : 357)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	153	Target Neighborhood Hits	147	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

FAT2_HUMAN
NC score	0.066388 (rank : 358)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	153	Target Neighborhood Hits	507	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

KR108_HUMAN
NC score	0.066238 (rank : 359)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	153	Target Neighborhood Hits	226	Shared Neighborhood Hits	43
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LAMC2_MOUSE
NC score	0.066089 (rank : 360)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	153	Target Neighborhood Hits	614	Shared Neighborhood Hits	67
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

NTNG1_HUMAN
NC score	0.066036 (rank : 361)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	153	Target Neighborhood Hits	247	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

ITB5_MOUSE
NC score	0.065639 (rank : 362)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	153	Target Neighborhood Hits	329	Shared Neighborhood Hits	72
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

TM11E_MOUSE
NC score	0.065472 (rank : 363)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

ATS15_HUMAN
NC score	0.065266 (rank : 364)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	153	Target Neighborhood Hits	151	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

TM11D_MOUSE
NC score	0.065222 (rank : 365)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

MEGF9_MOUSE
NC score	0.064610 (rank : 366)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	153	Target Neighborhood Hits	896	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

POLS2_HUMAN
NC score	0.064584 (rank : 367)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	153	Target Neighborhood Hits	192	Shared Neighborhood Hits	22
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

DESC4_MOUSE
NC score	0.064428 (rank : 368)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

CFAB_HUMAN
NC score	0.064292 (rank : 369)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	153	Target Neighborhood Hits	251	Shared Neighborhood Hits	25
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

ATS14_HUMAN
NC score	0.064291 (rank : 370)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	153	Target Neighborhood Hits	382	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

TEST_HUMAN
NC score	0.064099 (rank : 371)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	153	Target Neighborhood Hits	172	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TMPS5_HUMAN
NC score	0.063886 (rank : 372)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	153	Target Neighborhood Hits	181	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

ATS7_HUMAN
NC score	0.063851 (rank : 373)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	153	Target Neighborhood Hits	169	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

POLS2_MOUSE
NC score	0.063730 (rank : 374)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	153	Target Neighborhood Hits	188	Shared Neighborhood Hits	21
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

ACRO_HUMAN
NC score	0.063508 (rank : 375)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	153	Target Neighborhood Hits	291	Shared Neighborhood Hits	22
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TEFF2_MOUSE
NC score	0.063506 (rank : 376)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	153	Target Neighborhood Hits	214	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

CO2_MOUSE
NC score	0.063458 (rank : 377)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	153	Target Neighborhood Hits	250	Shared Neighborhood Hits	25
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

TM11D_HUMAN
NC score	0.063430 (rank : 378)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TMPS5_MOUSE
NC score	0.063403 (rank : 379)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	153	Target Neighborhood Hits	185	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

HEPS_MOUSE
NC score	0.063244 (rank : 380)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

USH2A_HUMAN
NC score	0.063243 (rank : 381)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	153	Target Neighborhood Hits	600	Shared Neighborhood Hits	71
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LYAM3_MOUSE
NC score	0.063162 (rank : 382)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	153	Target Neighborhood Hits	390	Shared Neighborhood Hits	67
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TENN_MOUSE
NC score	0.063095 (rank : 383)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	153	Target Neighborhood Hits	484	Shared Neighborhood Hits	71
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

KLKB1_MOUSE
NC score	0.063065 (rank : 384)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KR412_HUMAN
NC score	0.063061 (rank : 385)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

ITB6_HUMAN
NC score	0.062787 (rank : 386)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	153	Target Neighborhood Hits	318	Shared Neighborhood Hits	68
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

CSMD2_HUMAN
NC score	0.062738 (rank : 387)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	153	Target Neighborhood Hits	188	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

FA11_MOUSE
NC score	0.062706 (rank : 388)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

HEPS_HUMAN
NC score	0.062704 (rank : 389)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

PRSS8_MOUSE
NC score	0.062669 (rank : 390)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

CELR3_HUMAN
NC score	0.062617 (rank : 391)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	153	Target Neighborhood Hits	680	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

NFX1_HUMAN
NC score	0.062573 (rank : 392)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	153	Target Neighborhood Hits	405	Shared Neighborhood Hits	45
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

TEFF2_HUMAN
NC score	0.062504 (rank : 393)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	153	Target Neighborhood Hits	211	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

CILP2_HUMAN
NC score	0.062220 (rank : 394)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	153	Target Neighborhood Hits	307	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

FA11_HUMAN
NC score	0.062196 (rank : 395)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

LYAM3_HUMAN
NC score	0.062134 (rank : 396)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	153	Target Neighborhood Hits	378	Shared Neighborhood Hits	64
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

KLKB1_HUMAN
NC score	0.062109 (rank : 397)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	153	Target Neighborhood Hits	183	Shared Neighborhood Hits	21
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

LYAM2_MOUSE
NC score	0.061975 (rank : 398)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	153	Target Neighborhood Hits	420	Shared Neighborhood Hits	66
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ACRO_MOUSE
NC score	0.061960 (rank : 399)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	153	Target Neighborhood Hits	185	Shared Neighborhood Hits	21
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

PRS27_HUMAN
NC score	0.061936 (rank : 400)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRSS8_HUMAN
NC score	0.061842 (rank : 401)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	22
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRS27_MOUSE
NC score	0.061794 (rank : 402)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

TEST_MOUSE
NC score	0.061646 (rank : 403)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

CFAB_MOUSE
NC score	0.061507 (rank : 404)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	153	Target Neighborhood Hits	262	Shared Neighborhood Hits	25
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

TRYG1_MOUSE
NC score	0.061331 (rank : 405)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	153	Target Neighborhood Hits	181	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TMSP8_MOUSE
NC score	0.061308 (rank : 406)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TRYG1_HUMAN
NC score	0.061291 (rank : 407)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

BSSP4_HUMAN
NC score	0.061238 (rank : 408)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

TSP50_HUMAN
NC score	0.061169 (rank : 409)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

CELR2_HUMAN
NC score	0.061168 (rank : 410)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	153	Target Neighborhood Hits	657	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

PCOC2_MOUSE
NC score	0.060866 (rank : 411)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	153	Target Neighborhood Hits	73	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

KRA44_HUMAN
NC score	0.060859 (rank : 412)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	153	Target Neighborhood Hits	162	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

ITB5_HUMAN
NC score	0.060748 (rank : 413)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	153	Target Neighborhood Hits	310	Shared Neighborhood Hits	71
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

SMDF_HUMAN
NC score	0.060740 (rank : 414)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	153	Target Neighborhood Hits	117	Shared Neighborhood Hits	50
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

CELR1_HUMAN
NC score	0.060504 (rank : 415)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	153	Target Neighborhood Hits	613	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

TENN_HUMAN
NC score	0.060380 (rank : 416)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	153	Target Neighborhood Hits	453	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

NRG4_HUMAN
NC score	0.060296 (rank : 417)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	153	Target Neighborhood Hits	85	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

BSSP4_MOUSE
NC score	0.060272 (rank : 418)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

PCOC2_HUMAN
NC score	0.060216 (rank : 419)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	153	Target Neighborhood Hits	73	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

KR414_HUMAN
NC score	0.060173 (rank : 420)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	153	Target Neighborhood Hits	199	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

CLCR_HUMAN
NC score	0.060130 (rank : 421)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CSMD1_HUMAN
NC score	0.059663 (rank : 422)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

ITB3_MOUSE
NC score	0.059502 (rank : 423)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	153	Target Neighborhood Hits	319	Shared Neighborhood Hits	63
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

CTRL_HUMAN
NC score	0.059434 (rank : 424)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

CELR1_MOUSE
NC score	0.059388 (rank : 425)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	153	Target Neighborhood Hits	617	Shared Neighborhood Hits	81
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

LAMB3_MOUSE
NC score	0.059361 (rank : 426)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	153	Target Neighborhood Hits	444	Shared Neighborhood Hits	61
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

CTRB1_HUMAN
NC score	0.059315 (rank : 427)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

SEZ6L_HUMAN
NC score	0.059288 (rank : 428)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	153	Target Neighborhood Hits	289	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CSMD1_MOUSE
NC score	0.059230 (rank : 429)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	153	Target Neighborhood Hits	193	Shared Neighborhood Hits	29
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

ELA2A_MOUSE
NC score	0.059217 (rank : 430)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ITB7_HUMAN
NC score	0.058922 (rank : 431)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	153	Target Neighborhood Hits	290	Shared Neighborhood Hits	66
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

PCOC1_HUMAN
NC score	0.058888 (rank : 432)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	153	Target Neighborhood Hits	146	Shared Neighborhood Hits	20
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

CELR3_MOUSE
NC score	0.058798 (rank : 433)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	153	Target Neighborhood Hits	687	Shared Neighborhood Hits	80
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

MCPT6_MOUSE
NC score	0.058716 (rank : 434)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

NETR_MOUSE
NC score	0.058701 (rank : 435)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	153	Target Neighborhood Hits	216	Shared Neighborhood Hits	21
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

PCOC1_MOUSE
NC score	0.058493 (rank : 436)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	153	Target Neighborhood Hits	100	Shared Neighborhood Hits	20
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

LAMA4_MOUSE
NC score	0.058424 (rank : 437)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	153	Target Neighborhood Hits	584	Shared Neighborhood Hits	64
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TRYB1_HUMAN
NC score	0.058094 (rank : 438)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.058094 (rank : 439)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

THRB_HUMAN
NC score	0.058046 (rank : 440)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	153	Target Neighborhood Hits	196	Shared Neighborhood Hits	21
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

ITB1_MOUSE
NC score	0.057887 (rank : 441)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	153	Target Neighborhood Hits	283	Shared Neighborhood Hits	62
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ELA2A_HUMAN
NC score	0.057886 (rank : 442)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

TRYA1_HUMAN
NC score	0.057885 (rank : 443)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

PLMN_MOUSE
NC score	0.057870 (rank : 444)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	153	Target Neighborhood Hits	208	Shared Neighborhood Hits	26
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

NETR_HUMAN
NC score	0.057787 (rank : 445)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	153	Target Neighborhood Hits	218	Shared Neighborhood Hits	21
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

TRYB1_MOUSE
NC score	0.057739 (rank : 446)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

KR105_HUMAN
NC score	0.057640 (rank : 447)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	153	Target Neighborhood Hits	271	Shared Neighborhood Hits	46
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

ELTD1_HUMAN
NC score	0.057617 (rank : 448)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	153	Target Neighborhood Hits	269	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

LYAM2_HUMAN
NC score	0.057530 (rank : 449)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	153	Target Neighborhood Hits	394	Shared Neighborhood Hits	64
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ELA2B_HUMAN
NC score	0.057524 (rank : 450)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

GRAM_HUMAN
NC score	0.057071 (rank : 451)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

ZAN_HUMAN
NC score	0.056961 (rank : 452)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	153	Target Neighborhood Hits	679	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

RECK_MOUSE
NC score	0.056907 (rank : 453)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	153	Target Neighborhood Hits	158	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

LAMB3_HUMAN
NC score	0.056880 (rank : 454)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	153	Target Neighborhood Hits	461	Shared Neighborhood Hits	55
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

ELA3B_HUMAN
NC score	0.056803 (rank : 455)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

THRB_MOUSE
NC score	0.056712 (rank : 456)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	153	Target Neighborhood Hits	195	Shared Neighborhood Hits	21
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TRYD_HUMAN
NC score	0.056606 (rank : 457)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

LAMA4_HUMAN
NC score	0.056606 (rank : 458)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	153	Target Neighborhood Hits	708	Shared Neighborhood Hits	67
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

PLMN_HUMAN
NC score	0.056461 (rank : 459)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

APOA_HUMAN
NC score	0.056434 (rank : 460)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	153	Target Neighborhood Hits	221	Shared Neighborhood Hits	24
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

ELA3A_HUMAN
NC score	0.056331 (rank : 461)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	153	Target Neighborhood Hits	173	Shared Neighborhood Hits	21
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

NRX1A_MOUSE
NC score	0.056252 (rank : 462)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	153	Target Neighborhood Hits	164	Shared Neighborhood Hits	54
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

ATS4_MOUSE
NC score	0.056222 (rank : 463)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	153	Target Neighborhood Hits	145	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

NRX1A_HUMAN
NC score	0.056023 (rank : 464)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	153	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

VWF_HUMAN
NC score	0.055841 (rank : 465)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	153	Target Neighborhood Hits	396	Shared Neighborhood Hits	61
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ELA1_HUMAN
NC score	0.055753 (rank : 466)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

HPT_MOUSE
NC score	0.055369 (rank : 467)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

KRA55_HUMAN
NC score	0.055322 (rank : 468)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	153	Target Neighborhood Hits	257	Shared Neighborhood Hits	46
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

HPT_HUMAN
NC score	0.055303 (rank : 469)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	153	Target Neighborhood Hits	184	Shared Neighborhood Hits	22
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

TRY2_MOUSE
NC score	0.055062 (rank : 470)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

KR171_HUMAN
NC score	0.055025 (rank : 471)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	153	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

CSMD3_HUMAN
NC score	0.054948 (rank : 472)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	153	Target Neighborhood Hits	199	Shared Neighborhood Hits	31
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

KLK14_HUMAN
NC score	0.054824 (rank : 473)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

TRY1_HUMAN
NC score	0.054770 (rank : 474)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	22
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

HGFL_MOUSE
NC score	0.054687 (rank : 475)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	153	Target Neighborhood Hits	188	Shared Neighborhood Hits	22
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

TSG6_MOUSE
NC score	0.054680 (rank : 476)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

KLK13_HUMAN
NC score	0.054637 (rank : 477)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KRA11_HUMAN
NC score	0.054530 (rank : 478)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	153	Target Neighborhood Hits	155	Shared Neighborhood Hits	29
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

ITB4_HUMAN
NC score	0.054503 (rank : 479)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	153	Target Neighborhood Hits	458	Shared Neighborhood Hits	65
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

HGFL_HUMAN
NC score	0.054497 (rank : 480)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	153	Target Neighborhood Hits	190	Shared Neighborhood Hits	22
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

TRY2_HUMAN
NC score	0.054436 (rank : 481)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

CFAD_HUMAN
NC score	0.054398 (rank : 482)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

TRY3_HUMAN
NC score	0.054389 (rank : 483)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

KLK6_HUMAN
NC score	0.054378 (rank : 484)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

TSG6_HUMAN
NC score	0.054341 (rank : 485)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

KRA94_HUMAN
NC score	0.054251 (rank : 486)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

ATS5_HUMAN
NC score	0.054121 (rank : 487)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	153	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS4_HUMAN
NC score	0.054023 (rank : 488)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	153	Target Neighborhood Hits	138	Shared Neighborhood Hits	26
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

KRA13_HUMAN
NC score	0.054011 (rank : 489)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	153	Target Neighborhood Hits	144	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

ITB2_MOUSE
NC score	0.054006 (rank : 490)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	153	Target Neighborhood Hits	326	Shared Neighborhood Hits	62
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

NRPN_HUMAN
NC score	0.054002 (rank : 491)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	153	Target Neighborhood Hits	182	Shared Neighborhood Hits	21
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

KLK4_HUMAN
NC score	0.053908 (rank : 492)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

CFAD_MOUSE
NC score	0.053857 (rank : 493)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

KRA47_HUMAN
NC score	0.053803 (rank : 494)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	153	Target Neighborhood Hits	204	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KLK7_MOUSE
NC score	0.053747 (rank : 495)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK5_HUMAN
NC score	0.053676 (rank : 496)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	153	Target Neighborhood Hits	182	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

CLC14_MOUSE
NC score	0.053527 (rank : 497)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	153	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

LAMA3_HUMAN
NC score	0.053404 (rank : 498)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	153	Target Neighborhood Hits	760	Shared Neighborhood Hits	66
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

KRA54_HUMAN
NC score	0.053387 (rank : 499)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	153	Target Neighborhood Hits	270	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

GRAK_MOUSE
NC score	0.053384 (rank : 500)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

KLK7_HUMAN
NC score	0.053324 (rank : 501)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK10_HUMAN
NC score	0.053300 (rank : 502)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	153	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

CAP7_HUMAN
NC score	0.053274 (rank : 503)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	153	Target Neighborhood Hits	169	Shared Neighborhood Hits	21
SwissProt Accessions	P20160, P80014, Q52LG4	Gene names	AZU1
Domain Architecture
Description	Azurocidin precursor (Cationic antimicrobial protein CAP37) (Heparin- binding protein) (HBP).

NRG4_MOUSE
NC score	0.053197 (rank : 504)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	153	Target Neighborhood Hits	79	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

KLK15_HUMAN
NC score	0.053096 (rank : 505)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

PHXR5_MOUSE
NC score	0.052994 (rank : 506)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	153	Target Neighborhood Hits	102	Shared Neighborhood Hits	19
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

HPTR_HUMAN
NC score	0.052991 (rank : 507)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	153	Target Neighborhood Hits	166	Shared Neighborhood Hits	21
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

KRA99_HUMAN
NC score	0.052808 (rank : 508)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	153	Target Neighborhood Hits	173	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

CELR2_MOUSE
NC score	0.052756 (rank : 509)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	153	Target Neighborhood Hits	584	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

KRA98_HUMAN
NC score	0.052514 (rank : 510)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	153	Target Neighborhood Hits	185	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KLK11_HUMAN
NC score	0.052406 (rank : 511)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

KLK12_HUMAN
NC score	0.052369 (rank : 512)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	153	Target Neighborhood Hits	197	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

NRPN_MOUSE
NC score	0.052345 (rank : 513)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	153	Target Neighborhood Hits	186	Shared Neighborhood Hits	22
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

NRX3A_HUMAN
NC score	0.052206 (rank : 514)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	153	Target Neighborhood Hits	164	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

KLK9_HUMAN
NC score	0.052075 (rank : 515)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

K1KB1_MOUSE
NC score	0.052031 (rank : 516)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	23
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

THSD1_MOUSE
NC score	0.051977 (rank : 517)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	153	Target Neighborhood Hits	153	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

MCPT1_MOUSE
NC score	0.051972 (rank : 518)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

CATG_HUMAN
NC score	0.051911 (rank : 519)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

CUZD1_MOUSE
NC score	0.051859 (rank : 520)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	153	Target Neighborhood Hits	91	Shared Neighborhood Hits	18
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

CUZD1_HUMAN
NC score	0.051854 (rank : 521)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	153	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

ITB8_HUMAN
NC score	0.051709 (rank : 522)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	153	Target Neighborhood Hits	280	Shared Neighborhood Hits	65
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KLK11_MOUSE
NC score	0.051395 (rank : 523)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

CATG_MOUSE
NC score	0.051267 (rank : 524)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

HGF_HUMAN
NC score	0.051120 (rank : 525)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	153	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HGF_MOUSE
NC score	0.051107 (rank : 526)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	153	Target Neighborhood Hits	192	Shared Neighborhood Hits	22
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

ELNE_MOUSE
NC score	0.051011 (rank : 527)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	153	Target Neighborhood Hits	167	Shared Neighborhood Hits	21
SwissProt Accessions	Q3UP87, Q61515	Gene names	Ela2
Domain Architecture	No domain graphic available
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase).

K1KB3_MOUSE
NC score	0.050927 (rank : 528)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

K1KB9_MOUSE
NC score	0.050922 (rank : 529)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

MCPT4_MOUSE
NC score	0.050766 (rank : 530)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

MUC5B_HUMAN
NC score	0.050715 (rank : 531)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	153	Target Neighborhood Hits	1020	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

K1B22_MOUSE
NC score	0.050682 (rank : 532)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	153	Target Neighborhood Hits	174	Shared Neighborhood Hits	21
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

GRAH_HUMAN
NC score	0.050647 (rank : 533)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

ELNE_HUMAN
NC score	0.050564 (rank : 534)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	153	Target Neighborhood Hits	164	Shared Neighborhood Hits	21
SwissProt Accessions	P08246, P09649, Q6B0D9, Q6LDP5	Gene names	ELA2
Domain Architecture
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase) (PMN elastase) (Bone marrow serine protease) (Medullasin) (Human leukocyte elastase) (HLE).

K1B26_MOUSE
NC score	0.050531 (rank : 535)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

MCPT2_MOUSE
NC score	0.050528 (rank : 536)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	153	Target Neighborhood Hits	175	Shared Neighborhood Hits	21
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

KLK1_MOUSE
NC score	0.050502 (rank : 537)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

ASTN_MOUSE
NC score	0.050469 (rank : 538)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	153	Target Neighborhood Hits	98	Shared Neighborhood Hits	29
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

K1KB5_MOUSE
NC score	0.050417 (rank : 539)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	153	Target Neighborhood Hits	177	Shared Neighborhood Hits	21
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

K1B21_MOUSE
NC score	0.050408 (rank : 540)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	153	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

EGFB2_MOUSE
NC score	0.050331 (rank : 541)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

KLK2_HUMAN
NC score	0.050321 (rank : 542)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	153	Target Neighborhood Hits	176	Shared Neighborhood Hits	21
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

KRA92_HUMAN
NC score	0.050200 (rank : 543)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	153	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

K1B11_MOUSE
NC score	0.050067 (rank : 544)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	153	Target Neighborhood Hits	180	Shared Neighborhood Hits	21
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

KRA93_HUMAN
NC score	0.050049 (rank : 545)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	153	Target Neighborhood Hits	203	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

FAM5B_MOUSE
NC score	0.047980 (rank : 546)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	153	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

FAM5B_HUMAN
NC score	0.046068 (rank : 547)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	153	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

FAM5C_MOUSE
NC score	0.036789 (rank : 548)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	153	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q499E0, Q8K0R9	Gene names	Fam5c
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor.

FAM5C_HUMAN
NC score	0.035546 (rank : 549)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	153	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q76B58, O95726	Gene names	FAM5C, DBCCR1L, DBCCR1L1
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor (DBCCR1-like protein 1).

TIE1_HUMAN
NC score	0.035358 (rank : 550)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	153	Target Neighborhood Hits	1241	Shared Neighborhood Hits	76
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
NC score	0.034829 (rank : 551)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	153	Target Neighborhood Hits	1266	Shared Neighborhood Hits	75
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

ADAM7_MOUSE
NC score	0.026458 (rank : 552)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	153	Target Neighborhood Hits	200	Shared Neighborhood Hits	39
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

RSPO2_HUMAN
NC score	0.023762 (rank : 553)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	153	Target Neighborhood Hits	90	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

CLUS_HUMAN
NC score	0.011373 (rank : 554)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	153	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P10909, P11380, P11381, Q7Z5B9	Gene names	CLU
Domain Architecture
Description	Clusterin precursor (Complement-associated protein SP-40,40) (Complement cytolysis inhibitor) (CLI) (NA1/NA2) (Apolipoprotein J) (Apo-J) (Testosterone-repressed prostate message 2) (TRPM-2) [Contains: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain)].

NAL10_MOUSE
NC score	0.007974 (rank : 555)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	153	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CCN1	Gene names	Nalp10, Pynod
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 10.

SHE_HUMAN
NC score	0.004178 (rank : 556)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	153	Target Neighborhood Hits	164	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VZ18, Q8TEQ5	Gene names	SHE
Domain Architecture	No domain graphic available
Description	SH2 domain-containing adapter protein E.

PIWL1_MOUSE
NC score	0.004120 (rank : 557)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	153	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JMB7	Gene names	Piwil1, Miwi
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

DDX49_HUMAN
NC score	0.002956 (rank : 558)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	153	Target Neighborhood Hits	223	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

KPCA_MOUSE
NC score	-0.000675 (rank : 559)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	153	Target Neighborhood Hits	1067	Shared Neighborhood Hits	6
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_HUMAN
NC score	-0.001280 (rank : 560)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	153	Target Neighborhood Hits	1070	Shared Neighborhood Hits	6
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).