Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : ATS2_HUMAN

For an explanation of this page, click here

ATS2_HUMAN
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ATS14_HUMAN
θ value	0 (rank : 1)	NC score	0.980931 (rank : 4)
Query Neighborhood Hits	179	Target Neighborhood Hits	382	Shared Neighborhood Hits	134
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS2_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	179	Target Neighborhood Hits	179	Shared Neighborhood Hits	179
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
θ value	0 (rank : 3)	NC score	0.997925 (rank : 2)
Query Neighborhood Hits	179	Target Neighborhood Hits	179	Shared Neighborhood Hits	145
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
θ value	0 (rank : 4)	NC score	0.992395 (rank : 3)
Query Neighborhood Hits	179	Target Neighborhood Hits	179	Shared Neighborhood Hits	140
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS18_HUMAN
θ value	5.59392e-143 (rank : 5)	NC score	0.971080 (rank : 6)
Query Neighborhood Hits	179	Target Neighborhood Hits	169	Shared Neighborhood Hits	127
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
θ value	2.12569e-142 (rank : 6)	NC score	0.972317 (rank : 5)
Query Neighborhood Hits	179	Target Neighborhood Hits	163	Shared Neighborhood Hits	127
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_HUMAN
θ value	2.51683e-135 (rank : 7)	NC score	0.968176 (rank : 8)
Query Neighborhood Hits	179	Target Neighborhood Hits	208	Shared Neighborhood Hits	130
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS12_MOUSE
θ value	7.33985e-127 (rank : 8)	NC score	0.967357 (rank : 10)
Query Neighborhood Hits	179	Target Neighborhood Hits	220	Shared Neighborhood Hits	128
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS20_HUMAN
θ value	1.63515e-126 (rank : 9)	NC score	0.960374 (rank : 22)
Query Neighborhood Hits	179	Target Neighborhood Hits	192	Shared Neighborhood Hits	132
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	2.78914e-126 (rank : 10)	NC score	0.961767 (rank : 19)
Query Neighborhood Hits	179	Target Neighborhood Hits	225	Shared Neighborhood Hits	132
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS16_MOUSE
θ value	8.97236e-125 (rank : 11)	NC score	0.967946 (rank : 9)
Query Neighborhood Hits	179	Target Neighborhood Hits	179	Shared Neighborhood Hits	128
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS9_HUMAN
θ value	1.99884e-124 (rank : 12)	NC score	0.961545 (rank : 20)
Query Neighborhood Hits	179	Target Neighborhood Hits	219	Shared Neighborhood Hits	133
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS12_HUMAN
θ value	7.86017e-121 (rank : 13)	NC score	0.964939 (rank : 14)
Query Neighborhood Hits	179	Target Neighborhood Hits	251	Shared Neighborhood Hits	129
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS19_HUMAN
θ value	9.60843e-119 (rank : 14)	NC score	0.961005 (rank : 21)
Query Neighborhood Hits	179	Target Neighborhood Hits	203	Shared Neighborhood Hits	126
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS17_HUMAN
θ value	3.65119e-118 (rank : 15)	NC score	0.969328 (rank : 7)
Query Neighborhood Hits	179	Target Neighborhood Hits	194	Shared Neighborhood Hits	137
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS15_HUMAN
θ value	7.6132e-116 (rank : 16)	NC score	0.966870 (rank : 11)
Query Neighborhood Hits	179	Target Neighborhood Hits	151	Shared Neighborhood Hits	125
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS19_MOUSE
θ value	9.94316e-116 (rank : 17)	NC score	0.961948 (rank : 18)
Query Neighborhood Hits	179	Target Neighborhood Hits	188	Shared Neighborhood Hits	128
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS1_MOUSE
θ value	1.53757e-108 (rank : 18)	NC score	0.963868 (rank : 16)
Query Neighborhood Hits	179	Target Neighborhood Hits	158	Shared Neighborhood Hits	129
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS6_HUMAN
θ value	5.46864e-106 (rank : 19)	NC score	0.965753 (rank : 12)
Query Neighborhood Hits	179	Target Neighborhood Hits	141	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS1_HUMAN
θ value	7.39111e-103 (rank : 20)	NC score	0.964300 (rank : 15)
Query Neighborhood Hits	179	Target Neighborhood Hits	159	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS7_HUMAN
θ value	4.05562e-101 (rank : 21)	NC score	0.965379 (rank : 13)
Query Neighborhood Hits	179	Target Neighborhood Hits	169	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS8_HUMAN
θ value	1.22112e-97 (rank : 22)	NC score	0.963447 (rank : 17)
Query Neighborhood Hits	179	Target Neighborhood Hits	145	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS8_MOUSE
θ value	5.30912e-93 (rank : 23)	NC score	0.959096 (rank : 24)
Query Neighborhood Hits	179	Target Neighborhood Hits	139	Shared Neighborhood Hits	117
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS13_MOUSE
θ value	2.63489e-92 (rank : 24)	NC score	0.944861 (rank : 28)
Query Neighborhood Hits	179	Target Neighborhood Hits	227	Shared Neighborhood Hits	128
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS5_MOUSE
θ value	4.96919e-91 (rank : 25)	NC score	0.959289 (rank : 23)
Query Neighborhood Hits	179	Target Neighborhood Hits	147	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS5_HUMAN
θ value	2.46618e-90 (rank : 26)	NC score	0.956915 (rank : 25)
Query Neighborhood Hits	179	Target Neighborhood Hits	141	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS13_HUMAN
θ value	9.37149e-90 (rank : 27)	NC score	0.944352 (rank : 29)
Query Neighborhood Hits	179	Target Neighborhood Hits	238	Shared Neighborhood Hits	129
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS4_HUMAN
θ value	4.07447e-85 (rank : 28)	NC score	0.951837 (rank : 27)
Query Neighborhood Hits	179	Target Neighborhood Hits	138	Shared Neighborhood Hits	114
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS4_MOUSE
θ value	4.07447e-85 (rank : 29)	NC score	0.951955 (rank : 26)
Query Neighborhood Hits	179	Target Neighborhood Hits	145	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATL1_HUMAN
θ value	1.15626e-55 (rank : 30)	NC score	0.907442 (rank : 30)
Query Neighborhood Hits	179	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL3_HUMAN
θ value	5.55816e-50 (rank : 31)	NC score	0.760285 (rank : 35)
Query Neighborhood Hits	179	Target Neighborhood Hits	414	Shared Neighborhood Hits	90
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATL1_MOUSE
θ value	1.12253e-42 (rank : 32)	NC score	0.900461 (rank : 31)
Query Neighborhood Hits	179	Target Neighborhood Hits	80	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL2_HUMAN
θ value	2.19075e-38 (rank : 33)	NC score	0.866379 (rank : 34)
Query Neighborhood Hits	179	Target Neighborhood Hits	125	Shared Neighborhood Hits	81
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	8.32485e-38 (rank : 34)	NC score	0.866669 (rank : 33)
Query Neighborhood Hits	179	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL5_HUMAN
θ value	7.54701e-31 (rank : 35)	NC score	0.896899 (rank : 32)
Query Neighborhood Hits	179	Target Neighborhood Hits	103	Shared Neighborhood Hits	76
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ADA19_HUMAN
θ value	1.86321e-21 (rank : 36)	NC score	0.538414 (rank : 45)
Query Neighborhood Hits	179	Target Neighborhood Hits	381	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
θ value	2.06002e-20 (rank : 37)	NC score	0.545881 (rank : 44)
Query Neighborhood Hits	179	Target Neighborhood Hits	315	Shared Neighborhood Hits	90
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA28_MOUSE
θ value	3.51386e-20 (rank : 38)	NC score	0.547663 (rank : 42)
Query Neighborhood Hits	179	Target Neighborhood Hits	241	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADAM8_HUMAN
θ value	4.58923e-20 (rank : 39)	NC score	0.550345 (rank : 41)
Query Neighborhood Hits	179	Target Neighborhood Hits	327	Shared Neighborhood Hits	87
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADA28_HUMAN
θ value	2.7842e-17 (rank : 40)	NC score	0.535086 (rank : 46)
Query Neighborhood Hits	179	Target Neighborhood Hits	244	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADAM8_MOUSE
θ value	1.16975e-15 (rank : 41)	NC score	0.547280 (rank : 43)
Query Neighborhood Hits	179	Target Neighborhood Hits	326	Shared Neighborhood Hits	91
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CI094_HUMAN
θ value	1.52774e-15 (rank : 42)	NC score	0.575801 (rank : 40)
Query Neighborhood Hits	179	Target Neighborhood Hits	310	Shared Neighborhood Hits	75
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

BAI2_HUMAN
θ value	9.90251e-15 (rank : 43)	NC score	0.471555 (rank : 61)
Query Neighborhood Hits	179	Target Neighborhood Hits	332	Shared Neighborhood Hits	87
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ADA12_HUMAN
θ value	1.29331e-14 (rank : 44)	NC score	0.523046 (rank : 50)
Query Neighborhood Hits	179	Target Neighborhood Hits	224	Shared Neighborhood Hits	83
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BAI2_MOUSE
θ value	1.68911e-14 (rank : 45)	NC score	0.468921 (rank : 67)
Query Neighborhood Hits	179	Target Neighborhood Hits	323	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ADA12_MOUSE
θ value	2.20605e-14 (rank : 46)	NC score	0.514746 (rank : 51)
Query Neighborhood Hits	179	Target Neighborhood Hits	474	Shared Neighborhood Hits	92
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM7_HUMAN
θ value	2.88119e-14 (rank : 47)	NC score	0.511248 (rank : 52)
Query Neighborhood Hits	179	Target Neighborhood Hits	221	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

BAI3_HUMAN
θ value	6.41864e-14 (rank : 48)	NC score	0.470346 (rank : 63)
Query Neighborhood Hits	179	Target Neighborhood Hits	246	Shared Neighborhood Hits	84
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	2.43908e-13 (rank : 49)	NC score	0.469142 (rank : 66)
Query Neighborhood Hits	179	Target Neighborhood Hits	250	Shared Neighborhood Hits	85
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

ADAM7_MOUSE
θ value	4.16044e-13 (rank : 50)	NC score	0.509139 (rank : 53)
Query Neighborhood Hits	179	Target Neighborhood Hits	200	Shared Neighborhood Hits	81
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

SEM5A_HUMAN
θ value	5.43371e-13 (rank : 51)	NC score	0.436388 (rank : 88)
Query Neighborhood Hits	179	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ADAM9_HUMAN
θ value	7.09661e-13 (rank : 52)	NC score	0.492478 (rank : 58)
Query Neighborhood Hits	179	Target Neighborhood Hits	243	Shared Neighborhood Hits	84
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

TSP1_HUMAN
θ value	9.26847e-13 (rank : 53)	NC score	0.470330 (rank : 64)
Query Neighborhood Hits	179	Target Neighborhood Hits	389	Shared Neighborhood Hits	96
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	1.2105e-12 (rank : 54)	NC score	0.469747 (rank : 65)
Query Neighborhood Hits	179	Target Neighborhood Hits	396	Shared Neighborhood Hits	98
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

SEM5A_MOUSE
θ value	2.69671e-12 (rank : 55)	NC score	0.427257 (rank : 93)
Query Neighborhood Hits	179	Target Neighborhood Hits	162	Shared Neighborhood Hits	86
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

HMCN1_HUMAN
θ value	3.52202e-12 (rank : 56)	NC score	0.286978 (rank : 119)
Query Neighborhood Hits	179	Target Neighborhood Hits	983	Shared Neighborhood Hits	112
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

TSP2_HUMAN
θ value	3.52202e-12 (rank : 57)	NC score	0.463981 (rank : 71)
Query Neighborhood Hits	179	Target Neighborhood Hits	359	Shared Neighborhood Hits	94
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADA33_HUMAN
θ value	4.59992e-12 (rank : 58)	NC score	0.524156 (rank : 49)
Query Neighborhood Hits	179	Target Neighborhood Hits	264	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

TSP2_MOUSE
θ value	6.00763e-12 (rank : 59)	NC score	0.467294 (rank : 69)
Query Neighborhood Hits	179	Target Neighborhood Hits	352	Shared Neighborhood Hits	93
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADA15_HUMAN
θ value	7.84624e-12 (rank : 60)	NC score	0.501269 (rank : 54)
Query Neighborhood Hits	179	Target Neighborhood Hits	288	Shared Neighborhood Hits	87
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

PROP_HUMAN
θ value	1.33837e-11 (rank : 61)	NC score	0.639512 (rank : 36)
Query Neighborhood Hits	179	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

SEM5B_HUMAN
θ value	1.33837e-11 (rank : 62)	NC score	0.421783 (rank : 97)
Query Neighborhood Hits	179	Target Neighborhood Hits	178	Shared Neighborhood Hits	82
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ADEC1_HUMAN
θ value	1.74796e-11 (rank : 63)	NC score	0.532832 (rank : 47)
Query Neighborhood Hits	179	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

SEM5B_MOUSE
θ value	2.98157e-11 (rank : 64)	NC score	0.423327 (rank : 96)
Query Neighborhood Hits	179	Target Neighborhood Hits	190	Shared Neighborhood Hits	82
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

ADAM9_MOUSE
θ value	3.89403e-11 (rank : 65)	NC score	0.500337 (rank : 55)
Query Neighborhood Hits	179	Target Neighborhood Hits	325	Shared Neighborhood Hits	85
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

BAI1_MOUSE
θ value	6.64225e-11 (rank : 66)	NC score	0.468433 (rank : 68)
Query Neighborhood Hits	179	Target Neighborhood Hits	340	Shared Neighborhood Hits	86
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_HUMAN
θ value	1.133e-10 (rank : 67)	NC score	0.466139 (rank : 70)
Query Neighborhood Hits	179	Target Neighborhood Hits	375	Shared Neighborhood Hits	86
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

PROP_MOUSE
θ value	1.133e-10 (rank : 68)	NC score	0.632383 (rank : 37)
Query Neighborhood Hits	179	Target Neighborhood Hits	165	Shared Neighborhood Hits	83
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

ADA29_HUMAN
θ value	1.47974e-10 (rank : 69)	NC score	0.449956 (rank : 79)
Query Neighborhood Hits	179	Target Neighborhood Hits	247	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

SSPO_MOUSE
θ value	5.62301e-10 (rank : 70)	NC score	0.419920 (rank : 99)
Query Neighborhood Hits	179	Target Neighborhood Hits	800	Shared Neighborhood Hits	130
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SPON1_MOUSE
θ value	1.63604e-09 (rank : 71)	NC score	0.583813 (rank : 39)
Query Neighborhood Hits	179	Target Neighborhood Hits	123	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

ADA15_MOUSE
θ value	2.13673e-09 (rank : 72)	NC score	0.470645 (rank : 62)
Query Neighborhood Hits	179	Target Neighborhood Hits	324	Shared Neighborhood Hits	92
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

SPON1_HUMAN
θ value	3.64472e-09 (rank : 73)	NC score	0.585588 (rank : 38)
Query Neighborhood Hits	179	Target Neighborhood Hits	117	Shared Neighborhood Hits	84
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

ADA21_MOUSE
θ value	1.06045e-08 (rank : 74)	NC score	0.458632 (rank : 75)
Query Neighborhood Hits	179	Target Neighborhood Hits	172	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA33_MOUSE
θ value	1.06045e-08 (rank : 75)	NC score	0.494685 (rank : 56)
Query Neighborhood Hits	179	Target Neighborhood Hits	231	Shared Neighborhood Hits	84
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CILP2_HUMAN
θ value	1.06045e-08 (rank : 76)	NC score	0.420696 (rank : 98)
Query Neighborhood Hits	179	Target Neighborhood Hits	307	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CO6_HUMAN
θ value	3.08544e-08 (rank : 77)	NC score	0.427427 (rank : 92)
Query Neighborhood Hits	179	Target Neighborhood Hits	331	Shared Neighborhood Hits	83
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

UNC5B_MOUSE
θ value	4.0297e-08 (rank : 78)	NC score	0.462245 (rank : 72)
Query Neighborhood Hits	179	Target Neighborhood Hits	226	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
θ value	5.26297e-08 (rank : 79)	NC score	0.459759 (rank : 74)
Query Neighborhood Hits	179	Target Neighborhood Hits	225	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5A_MOUSE
θ value	6.87365e-08 (rank : 80)	NC score	0.472397 (rank : 60)
Query Neighborhood Hits	179	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ADA24_MOUSE
θ value	8.97725e-08 (rank : 81)	NC score	0.452365 (rank : 77)
Query Neighborhood Hits	179	Target Neighborhood Hits	230	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
θ value	1.53129e-07 (rank : 82)	NC score	0.447102 (rank : 80)
Query Neighborhood Hits	179	Target Neighborhood Hits	213	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

CO8A_HUMAN
θ value	1.53129e-07 (rank : 83)	NC score	0.434210 (rank : 90)
Query Neighborhood Hits	179	Target Neighborhood Hits	200	Shared Neighborhood Hits	73
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

UNC5C_MOUSE
θ value	7.59969e-07 (rank : 84)	NC score	0.444951 (rank : 83)
Query Neighborhood Hits	179	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

THSD1_HUMAN
θ value	9.92553e-07 (rank : 85)	NC score	0.528546 (rank : 48)
Query Neighborhood Hits	179	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

UNC5C_HUMAN
θ value	9.92553e-07 (rank : 86)	NC score	0.444414 (rank : 84)
Query Neighborhood Hits	179	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5D_MOUSE
θ value	9.92553e-07 (rank : 87)	NC score	0.432742 (rank : 91)
Query Neighborhood Hits	179	Target Neighborhood Hits	268	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ADA21_HUMAN
θ value	1.29631e-06 (rank : 88)	NC score	0.443628 (rank : 85)
Query Neighborhood Hits	179	Target Neighborhood Hits	181	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

UNC5D_HUMAN
θ value	1.29631e-06 (rank : 89)	NC score	0.436333 (rank : 89)
Query Neighborhood Hits	179	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5A_HUMAN
θ value	2.88788e-06 (rank : 90)	NC score	0.387034 (rank : 106)
Query Neighborhood Hits	179	Target Neighborhood Hits	198	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

THSD1_MOUSE
θ value	3.77169e-06 (rank : 91)	NC score	0.494560 (rank : 57)
Query Neighborhood Hits	179	Target Neighborhood Hits	153	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADEC1_MOUSE
θ value	4.92598e-06 (rank : 92)	NC score	0.477632 (rank : 59)
Query Neighborhood Hits	179	Target Neighborhood Hits	85	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

AD26A_MOUSE
θ value	6.43352e-06 (rank : 93)	NC score	0.438185 (rank : 86)
Query Neighborhood Hits	179	Target Neighborhood Hits	165	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

CO8B_HUMAN
θ value	6.43352e-06 (rank : 94)	NC score	0.372755 (rank : 109)
Query Neighborhood Hits	179	Target Neighborhood Hits	199	Shared Neighborhood Hits	67
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	1.09739e-05 (rank : 95)	NC score	0.409874 (rank : 100)
Query Neighborhood Hits	179	Target Neighborhood Hits	224	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADA22_MOUSE
θ value	1.43324e-05 (rank : 96)	NC score	0.445444 (rank : 81)
Query Neighborhood Hits	179	Target Neighborhood Hits	225	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

CILP1_HUMAN
θ value	1.43324e-05 (rank : 97)	NC score	0.312468 (rank : 118)
Query Neighborhood Hits	179	Target Neighborhood Hits	266	Shared Neighborhood Hits	76
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	1.87187e-05 (rank : 98)	NC score	0.313598 (rank : 117)
Query Neighborhood Hits	179	Target Neighborhood Hits	282	Shared Neighborhood Hits	75
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

ADA11_MOUSE
θ value	2.44474e-05 (rank : 99)	NC score	0.425645 (rank : 94)
Query Neighborhood Hits	179	Target Neighborhood Hits	263	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CO7_HUMAN
θ value	2.44474e-05 (rank : 100)	NC score	0.379237 (rank : 107)
Query Neighborhood Hits	179	Target Neighborhood Hits	278	Shared Neighborhood Hits	75
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

ADA22_HUMAN
θ value	3.19293e-05 (rank : 101)	NC score	0.454954 (rank : 76)
Query Neighborhood Hits	179	Target Neighborhood Hits	211	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADM1A_MOUSE
θ value	9.29e-05 (rank : 102)	NC score	0.452242 (rank : 78)
Query Neighborhood Hits	179	Target Neighborhood Hits	230	Shared Neighborhood Hits	84
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA23_MOUSE
θ value	0.000121331 (rank : 103)	NC score	0.445032 (rank : 82)
Query Neighborhood Hits	179	Target Neighborhood Hits	245	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_HUMAN
θ value	0.000158464 (rank : 104)	NC score	0.437086 (rank : 87)
Query Neighborhood Hits	179	Target Neighborhood Hits	235	Shared Neighborhood Hits	83
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADM1B_MOUSE
θ value	0.000158464 (rank : 105)	NC score	0.460183 (rank : 73)
Query Neighborhood Hits	179	Target Neighborhood Hits	236	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

CO8A_MOUSE
θ value	0.00020696 (rank : 106)	NC score	0.425114 (rank : 95)
Query Neighborhood Hits	179	Target Neighborhood Hits	182	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ADA11_HUMAN
θ value	0.000461057 (rank : 107)	NC score	0.400995 (rank : 101)
Query Neighborhood Hits	179	Target Neighborhood Hits	259	Shared Neighborhood Hits	82
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA32_HUMAN
θ value	0.000786445 (rank : 108)	NC score	0.392666 (rank : 104)
Query Neighborhood Hits	179	Target Neighborhood Hits	216	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	0.00228821 (rank : 109)	NC score	0.389412 (rank : 105)
Query Neighborhood Hits	179	Target Neighborhood Hits	219	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADAM2_MOUSE
θ value	0.00228821 (rank : 110)	NC score	0.398365 (rank : 103)
Query Neighborhood Hits	179	Target Neighborhood Hits	209	Shared Neighborhood Hits	81
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADA18_MOUSE
θ value	0.00509761 (rank : 111)	NC score	0.374590 (rank : 108)
Query Neighborhood Hits	179	Target Neighborhood Hits	227	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA20_HUMAN
θ value	0.00665767 (rank : 112)	NC score	0.400442 (rank : 102)
Query Neighborhood Hits	179	Target Neighborhood Hits	143	Shared Neighborhood Hits	83
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA30_HUMAN
θ value	0.00869519 (rank : 113)	NC score	0.346269 (rank : 112)
Query Neighborhood Hits	179	Target Neighborhood Hits	391	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA10_MOUSE
θ value	0.0736092 (rank : 114)	NC score	0.342648 (rank : 113)
Query Neighborhood Hits	179	Target Neighborhood Hits	194	Shared Neighborhood Hits	80
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA10_HUMAN
θ value	0.0961366 (rank : 115)	NC score	0.339784 (rank : 115)
Query Neighborhood Hits	179	Target Neighborhood Hits	189	Shared Neighborhood Hits	81
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADAM2_HUMAN
θ value	0.125558 (rank : 116)	NC score	0.361413 (rank : 110)
Query Neighborhood Hits	179	Target Neighborhood Hits	175	Shared Neighborhood Hits	78
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

PAPD1_MOUSE
θ value	0.125558 (rank : 117)	NC score	0.027102 (rank : 170)
Query Neighborhood Hits	179	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0D3, Q3UXJ1, Q8C651	Gene names	Papd1
Domain Architecture	No domain graphic available
Description	Poly(A) RNA polymerase, mitochondrial precursor (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase) (PAP-associated domain-containing protein 1).

CFAI_HUMAN
θ value	0.163984 (rank : 118)	NC score	0.009778 (rank : 189)
Query Neighborhood Hits	179	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CTGF_MOUSE
θ value	0.47712 (rank : 119)	NC score	0.084652 (rank : 130)
Query Neighborhood Hits	179	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

FBN2_HUMAN
θ value	0.47712 (rank : 120)	NC score	0.037483 (rank : 164)
Query Neighborhood Hits	179	Target Neighborhood Hits	560	Shared Neighborhood Hits	72
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

ZNFX1_MOUSE
θ value	0.62314 (rank : 121)	NC score	0.018108 (rank : 175)
Query Neighborhood Hits	179	Target Neighborhood Hits	407	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

MMP26_HUMAN
θ value	0.813845 (rank : 122)	NC score	0.046643 (rank : 159)
Query Neighborhood Hits	179	Target Neighborhood Hits	56	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

ADA18_HUMAN
θ value	1.06291 (rank : 123)	NC score	0.346439 (rank : 111)
Query Neighborhood Hits	179	Target Neighborhood Hits	184	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

CTGF_HUMAN
θ value	1.06291 (rank : 124)	NC score	0.080742 (rank : 134)
Query Neighborhood Hits	179	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

FRAS1_MOUSE
θ value	1.06291 (rank : 125)	NC score	0.088305 (rank : 128)
Query Neighborhood Hits	179	Target Neighborhood Hits	747	Shared Neighborhood Hits	91
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

IBP4_HUMAN
θ value	1.06291 (rank : 126)	NC score	0.009829 (rank : 188)
Query Neighborhood Hits	179	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

FAS_MOUSE
θ value	1.38821 (rank : 127)	NC score	0.010408 (rank : 187)
Query Neighborhood Hits	179	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	P19096, Q6PB72, Q8C4Z0, Q9EQR0	Gene names	Fasn
Domain Architecture	No domain graphic available
Description	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S- malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)].

TRIM1_HUMAN
θ value	1.38821 (rank : 128)	NC score	0.003825 (rank : 201)
Query Neighborhood Hits	179	Target Neighborhood Hits	345	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

FBN2_MOUSE
θ value	1.81305 (rank : 129)	NC score	0.038376 (rank : 163)
Query Neighborhood Hits	179	Target Neighborhood Hits	549	Shared Neighborhood Hits	72
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LRP1_HUMAN
θ value	1.81305 (rank : 130)	NC score	0.045963 (rank : 160)
Query Neighborhood Hits	179	Target Neighborhood Hits	617	Shared Neighborhood Hits	77
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MMP21_MOUSE
θ value	1.81305 (rank : 131)	NC score	0.020078 (rank : 172)
Query Neighborhood Hits	179	Target Neighborhood Hits	59	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3F2	Gene names	Mmp21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

PCLO_MOUSE
θ value	1.81305 (rank : 132)	NC score	0.004174 (rank : 200)
Query Neighborhood Hits	179	Target Neighborhood Hits	2275	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PRG4_MOUSE
θ value	1.81305 (rank : 133)	NC score	0.012532 (rank : 186)
Query Neighborhood Hits	179	Target Neighborhood Hits	624	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

VOME_MOUSE
θ value	1.81305 (rank : 134)	NC score	0.016114 (rank : 181)
Query Neighborhood Hits	179	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XI7, Q5XK13, Q8CDY1	Gene names
Domain Architecture	No domain graphic available
Description	Vomeromodulin precursor.

ADA17_HUMAN
θ value	2.36792 (rank : 135)	NC score	0.331591 (rank : 116)
Query Neighborhood Hits	179	Target Neighborhood Hits	223	Shared Neighborhood Hits	90
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	2.36792 (rank : 136)	NC score	0.342342 (rank : 114)
Query Neighborhood Hits	179	Target Neighborhood Hits	201	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

G3BP2_HUMAN
θ value	2.36792 (rank : 137)	NC score	0.006073 (rank : 194)
Query Neighborhood Hits	179	Target Neighborhood Hits	260	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

MMP2_HUMAN
θ value	2.36792 (rank : 138)	NC score	0.031042 (rank : 167)
Query Neighborhood Hits	179	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

MMP2_MOUSE
θ value	2.36792 (rank : 139)	NC score	0.029378 (rank : 169)
Query Neighborhood Hits	179	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

CS007_MOUSE
θ value	3.0926 (rank : 140)	NC score	0.006780 (rank : 191)
Query Neighborhood Hits	179	Target Neighborhood Hits	464	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

G3BP2_MOUSE
θ value	4.03905 (rank : 141)	NC score	0.005240 (rank : 198)
Query Neighborhood Hits	179	Target Neighborhood Hits	258	Shared Neighborhood Hits	3
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

LRP1B_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.047044 (rank : 158)
Query Neighborhood Hits	179	Target Neighborhood Hits	602	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MMP14_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.016129 (rank : 180)
Query Neighborhood Hits	179	Target Neighborhood Hits	60	Shared Neighborhood Hits	25
SwissProt Accessions	P50281, Q92678	Gene names	MMP14
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP- X1).

RSPO4_HUMAN
θ value	4.03905 (rank : 144)	NC score	0.062575 (rank : 145)
Query Neighborhood Hits	179	Target Neighborhood Hits	110	Shared Neighborhood Hits	33
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

TRI18_HUMAN
θ value	4.03905 (rank : 145)	NC score	0.002837 (rank : 203)
Query Neighborhood Hits	179	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	4.03905 (rank : 146)	NC score	0.003072 (rank : 202)
Query Neighborhood Hits	179	Target Neighborhood Hits	292	Shared Neighborhood Hits	4
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

ZN221_HUMAN
θ value	4.03905 (rank : 147)	NC score	-0.007461 (rank : 206)
Query Neighborhood Hits	179	Target Neighborhood Hits	784	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UK13, Q9P1U8	Gene names	ZNF221
Domain Architecture
Description	Zinc finger protein 221.

CAN12_MOUSE
θ value	5.27518 (rank : 148)	NC score	0.001392 (rank : 204)
Query Neighborhood Hits	179	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

CYR61_HUMAN
θ value	5.27518 (rank : 149)	NC score	0.107160 (rank : 124)
Query Neighborhood Hits	179	Target Neighborhood Hits	159	Shared Neighborhood Hits	65
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

LRP8_MOUSE
θ value	5.27518 (rank : 150)	NC score	0.031985 (rank : 165)
Query Neighborhood Hits	179	Target Neighborhood Hits	385	Shared Neighborhood Hits	51
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MMP21_HUMAN
θ value	5.27518 (rank : 151)	NC score	0.016428 (rank : 178)
Query Neighborhood Hits	179	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

SYMM_MOUSE
θ value	5.27518 (rank : 152)	NC score	0.005713 (rank : 195)
Query Neighborhood Hits	179	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

WISP1_MOUSE
θ value	5.27518 (rank : 153)	NC score	0.120396 (rank : 122)
Query Neighborhood Hits	179	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP3_HUMAN
θ value	5.27518 (rank : 154)	NC score	0.101218 (rank : 125)
Query Neighborhood Hits	179	Target Neighborhood Hits	87	Shared Neighborhood Hits	40
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

BTBDA_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.005658 (rank : 196)
Query Neighborhood Hits	179	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BSF8, Q86WG1	Gene names	BTBD10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

CPSF7_MOUSE
θ value	6.88961 (rank : 156)	NC score	0.006781 (rank : 190)
Query Neighborhood Hits	179	Target Neighborhood Hits	123	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

IBP4_MOUSE
θ value	6.88961 (rank : 157)	NC score	0.006708 (rank : 192)
Query Neighborhood Hits	179	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

MMP24_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.015889 (rank : 182)
Query Neighborhood Hits	179	Target Neighborhood Hits	66	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5R2, Q9H440	Gene names	MMP24, MT5MMP
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP).

MMP24_MOUSE
θ value	6.88961 (rank : 159)	NC score	0.017575 (rank : 176)
Query Neighborhood Hits	179	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R0S2, Q9Z0J9	Gene names	Mmp24, Mmp21, Mt5mmp
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MMP-21).

MMP9_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.018537 (rank : 174)
Query Neighborhood Hits	179	Target Neighborhood Hits	125	Shared Neighborhood Hits	24
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

MMP9_MOUSE
θ value	6.88961 (rank : 161)	NC score	0.021779 (rank : 171)
Query Neighborhood Hits	179	Target Neighborhood Hits	151	Shared Neighborhood Hits	27
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

NMDE3_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.004553 (rank : 199)
Query Neighborhood Hits	179	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

O2T34_HUMAN
θ value	6.88961 (rank : 163)	NC score	-0.008100 (rank : 207)
Query Neighborhood Hits	179	Target Neighborhood Hits	863	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGX1, Q6IEY5, Q96R31	Gene names	OR2T34
Domain Architecture	No domain graphic available
Description	Olfactory receptor 2T34 (Olfactory receptor OR1-63).

RSPO4_MOUSE
θ value	6.88961 (rank : 164)	NC score	0.083895 (rank : 132)
Query Neighborhood Hits	179	Target Neighborhood Hits	110	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

CPSF7_HUMAN
θ value	8.99809 (rank : 165)	NC score	0.006152 (rank : 193)
Query Neighborhood Hits	179	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

LTB1L_HUMAN
θ value	8.99809 (rank : 166)	NC score	0.031584 (rank : 166)
Query Neighborhood Hits	179	Target Neighborhood Hits	553	Shared Neighborhood Hits	61
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.030036 (rank : 168)
Query Neighborhood Hits	179	Target Neighborhood Hits	502	Shared Neighborhood Hits	58
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MMP11_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.017359 (rank : 177)
Query Neighborhood Hits	179	Target Neighborhood Hits	65	Shared Neighborhood Hits	27
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP15_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.015515 (rank : 183)
Query Neighborhood Hits	179	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

MMP16_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.014494 (rank : 185)
Query Neighborhood Hits	179	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

MMP16_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.014517 (rank : 184)
Query Neighborhood Hits	179	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

MMP1A_MOUSE
θ value	8.99809 (rank : 172)	NC score	0.016200 (rank : 179)
Query Neighborhood Hits	179	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

MMP1B_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.019723 (rank : 173)
Query Neighborhood Hits	179	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

PCSK5_MOUSE
θ value	8.99809 (rank : 174)	NC score	0.044415 (rank : 161)
Query Neighborhood Hits	179	Target Neighborhood Hits	613	Shared Neighborhood Hits	65
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

RSPO2_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.040708 (rank : 162)
Query Neighborhood Hits	179	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO3_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.058248 (rank : 149)
Query Neighborhood Hits	179	Target Neighborhood Hits	128	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

SOX13_HUMAN
θ value	8.99809 (rank : 177)	NC score	-0.001429 (rank : 205)
Query Neighborhood Hits	179	Target Neighborhood Hits	464	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

UBE4B_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.005643 (rank : 197)
Query Neighborhood Hits	179	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

ZAN_MOUSE
θ value	8.99809 (rank : 179)	NC score	0.055590 (rank : 151)
Query Neighborhood Hits	179	Target Neighborhood Hits	808	Shared Neighborhood Hits	82
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CO9_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.065370 (rank : 143)
Query Neighborhood Hits	179	Target Neighborhood Hits	147	Shared Neighborhood Hits	19
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.072563 (rank : 138)
Query Neighborhood Hits	179	Target Neighborhood Hits	153	Shared Neighborhood Hits	25
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.050105 (rank : 157)
Query Neighborhood Hits	179	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CYR61_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.090105 (rank : 127)
Query Neighborhood Hits	179	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

FRAS1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.073047 (rank : 137)
Query Neighborhood Hits	179	Target Neighborhood Hits	759	Shared Neighborhood Hits	88
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KR101_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.054657 (rank : 152)
Query Neighborhood Hits	179	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.069903 (rank : 140)
Query Neighborhood Hits	179	Target Neighborhood Hits	264	Shared Neighborhood Hits	47
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.080092 (rank : 135)
Query Neighborhood Hits	179	Target Neighborhood Hits	313	Shared Neighborhood Hits	55
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR106_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.083962 (rank : 131)
Query Neighborhood Hits	179	Target Neighborhood Hits	347	Shared Neighborhood Hits	61
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.063994 (rank : 144)
Query Neighborhood Hits	179	Target Neighborhood Hits	330	Shared Neighborhood Hits	49
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.061312 (rank : 147)
Query Neighborhood Hits	179	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.056111 (rank : 150)
Query Neighborhood Hits	179	Target Neighborhood Hits	331	Shared Neighborhood Hits	56
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA57_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.050224 (rank : 156)
Query Neighborhood Hits	179	Target Neighborhood Hits	269	Shared Neighborhood Hits	47
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.053123 (rank : 154)
Query Neighborhood Hits	179	Target Neighborhood Hits	324	Shared Neighborhood Hits	55
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA92_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.061953 (rank : 146)
Query Neighborhood Hits	179	Target Neighborhood Hits	198	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.059684 (rank : 148)
Query Neighborhood Hits	179	Target Neighborhood Hits	203	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA98_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.065930 (rank : 142)
Query Neighborhood Hits	179	Target Neighborhood Hits	185	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

NOV_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.086233 (rank : 129)
Query Neighborhood Hits	179	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.099001 (rank : 126)
Query Neighborhood Hits	179	Target Neighborhood Hits	130	Shared Neighborhood Hits	51
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

RSPO1_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.081609 (rank : 133)
Query Neighborhood Hits	179	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO1_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.070281 (rank : 139)
Query Neighborhood Hits	179	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO3_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.052396 (rank : 155)
Query Neighborhood Hits	179	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

SPON2_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.078309 (rank : 136)
Query Neighborhood Hits	179	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON2_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.066366 (rank : 141)
Query Neighborhood Hits	179	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

TENX_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.053501 (rank : 153)
Query Neighborhood Hits	179	Target Neighborhood Hits	789	Shared Neighborhood Hits	82
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

WISP1_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.111266 (rank : 123)
Query Neighborhood Hits	179	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP2_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.137696 (rank : 120)
Query Neighborhood Hits	179	Target Neighborhood Hits	126	Shared Neighborhood Hits	60
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.134077 (rank : 121)
Query Neighborhood Hits	179	Target Neighborhood Hits	129	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

Hits sorted by NC score

ATS2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	179	Target Neighborhood Hits	179	Shared Neighborhood Hits	179
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
NC score	0.997925 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	179	Target Neighborhood Hits	179	Shared Neighborhood Hits	145
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
NC score	0.992395 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	179	Target Neighborhood Hits	179	Shared Neighborhood Hits	140
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS14_HUMAN
NC score	0.980931 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	179	Target Neighborhood Hits	382	Shared Neighborhood Hits	134
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS18_MOUSE
NC score	0.972317 (rank : 5)	θ value	2.12569e-142 (rank : 6)
Query Neighborhood Hits	179	Target Neighborhood Hits	163	Shared Neighborhood Hits	127
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_HUMAN
NC score	0.971080 (rank : 6)	θ value	5.59392e-143 (rank : 5)
Query Neighborhood Hits	179	Target Neighborhood Hits	169	Shared Neighborhood Hits	127
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS17_HUMAN
NC score	0.969328 (rank : 7)	θ value	3.65119e-118 (rank : 15)
Query Neighborhood Hits	179	Target Neighborhood Hits	194	Shared Neighborhood Hits	137
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS16_HUMAN
NC score	0.968176 (rank : 8)	θ value	2.51683e-135 (rank : 7)
Query Neighborhood Hits	179	Target Neighborhood Hits	208	Shared Neighborhood Hits	130
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_MOUSE
NC score	0.967946 (rank : 9)	θ value	8.97236e-125 (rank : 11)
Query Neighborhood Hits	179	Target Neighborhood Hits	179	Shared Neighborhood Hits	128
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS12_MOUSE
NC score	0.967357 (rank : 10)	θ value	7.33985e-127 (rank : 8)
Query Neighborhood Hits	179	Target Neighborhood Hits	220	Shared Neighborhood Hits	128
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS15_HUMAN
NC score	0.966870 (rank : 11)	θ value	7.6132e-116 (rank : 16)
Query Neighborhood Hits	179	Target Neighborhood Hits	151	Shared Neighborhood Hits	125
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS6_HUMAN
NC score	0.965753 (rank : 12)	θ value	5.46864e-106 (rank : 19)
Query Neighborhood Hits	179	Target Neighborhood Hits	141	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS7_HUMAN
NC score	0.965379 (rank : 13)	θ value	4.05562e-101 (rank : 21)
Query Neighborhood Hits	179	Target Neighborhood Hits	169	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS12_HUMAN
NC score	0.964939 (rank : 14)	θ value	7.86017e-121 (rank : 13)
Query Neighborhood Hits	179	Target Neighborhood Hits	251	Shared Neighborhood Hits	129
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS1_HUMAN
NC score	0.964300 (rank : 15)	θ value	7.39111e-103 (rank : 20)
Query Neighborhood Hits	179	Target Neighborhood Hits	159	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS1_MOUSE
NC score	0.963868 (rank : 16)	θ value	1.53757e-108 (rank : 18)
Query Neighborhood Hits	179	Target Neighborhood Hits	158	Shared Neighborhood Hits	129
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS8_HUMAN
NC score	0.963447 (rank : 17)	θ value	1.22112e-97 (rank : 22)
Query Neighborhood Hits	179	Target Neighborhood Hits	145	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS19_MOUSE
NC score	0.961948 (rank : 18)	θ value	9.94316e-116 (rank : 17)
Query Neighborhood Hits	179	Target Neighborhood Hits	188	Shared Neighborhood Hits	128
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS20_MOUSE
NC score	0.961767 (rank : 19)	θ value	2.78914e-126 (rank : 10)
Query Neighborhood Hits	179	Target Neighborhood Hits	225	Shared Neighborhood Hits	132
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS9_HUMAN
NC score	0.961545 (rank : 20)	θ value	1.99884e-124 (rank : 12)
Query Neighborhood Hits	179	Target Neighborhood Hits	219	Shared Neighborhood Hits	133
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS19_HUMAN
NC score	0.961005 (rank : 21)	θ value	9.60843e-119 (rank : 14)
Query Neighborhood Hits	179	Target Neighborhood Hits	203	Shared Neighborhood Hits	126
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS20_HUMAN
NC score	0.960374 (rank : 22)	θ value	1.63515e-126 (rank : 9)
Query Neighborhood Hits	179	Target Neighborhood Hits	192	Shared Neighborhood Hits	132
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS5_MOUSE
NC score	0.959289 (rank : 23)	θ value	4.96919e-91 (rank : 25)
Query Neighborhood Hits	179	Target Neighborhood Hits	147	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS8_MOUSE
NC score	0.959096 (rank : 24)	θ value	5.30912e-93 (rank : 23)
Query Neighborhood Hits	179	Target Neighborhood Hits	139	Shared Neighborhood Hits	117
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS5_HUMAN
NC score	0.956915 (rank : 25)	θ value	2.46618e-90 (rank : 26)
Query Neighborhood Hits	179	Target Neighborhood Hits	141	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS4_MOUSE
NC score	0.951955 (rank : 26)	θ value	4.07447e-85 (rank : 29)
Query Neighborhood Hits	179	Target Neighborhood Hits	145	Shared Neighborhood Hits	116
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS4_HUMAN
NC score	0.951837 (rank : 27)	θ value	4.07447e-85 (rank : 28)
Query Neighborhood Hits	179	Target Neighborhood Hits	138	Shared Neighborhood Hits	114
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS13_MOUSE
NC score	0.944861 (rank : 28)	θ value	2.63489e-92 (rank : 24)
Query Neighborhood Hits	179	Target Neighborhood Hits	227	Shared Neighborhood Hits	128
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_HUMAN
NC score	0.944352 (rank : 29)	θ value	9.37149e-90 (rank : 27)
Query Neighborhood Hits	179	Target Neighborhood Hits	238	Shared Neighborhood Hits	129
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATL1_HUMAN
NC score	0.907442 (rank : 30)	θ value	1.15626e-55 (rank : 30)
Query Neighborhood Hits	179	Target Neighborhood Hits	93	Shared Neighborhood Hits	80
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
NC score	0.900461 (rank : 31)	θ value	1.12253e-42 (rank : 32)
Query Neighborhood Hits	179	Target Neighborhood Hits	80	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL5_HUMAN
NC score	0.896899 (rank : 32)	θ value	7.54701e-31 (rank : 35)
Query Neighborhood Hits	179	Target Neighborhood Hits	103	Shared Neighborhood Hits	76
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATL2_MOUSE
NC score	0.866669 (rank : 33)	θ value	8.32485e-38 (rank : 34)
Query Neighborhood Hits	179	Target Neighborhood Hits	137	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL2_HUMAN
NC score	0.866379 (rank : 34)	θ value	2.19075e-38 (rank : 33)
Query Neighborhood Hits	179	Target Neighborhood Hits	125	Shared Neighborhood Hits	81
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL3_HUMAN
NC score	0.760285 (rank : 35)	θ value	5.55816e-50 (rank : 31)
Query Neighborhood Hits	179	Target Neighborhood Hits	414	Shared Neighborhood Hits	90
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

PROP_HUMAN
NC score	0.639512 (rank : 36)	θ value	1.33837e-11 (rank : 61)
Query Neighborhood Hits	179	Target Neighborhood Hits	126	Shared Neighborhood Hits	78
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
NC score	0.632383 (rank : 37)	θ value	1.133e-10 (rank : 68)
Query Neighborhood Hits	179	Target Neighborhood Hits	165	Shared Neighborhood Hits	83
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

SPON1_HUMAN
NC score	0.585588 (rank : 38)	θ value	3.64472e-09 (rank : 73)
Query Neighborhood Hits	179	Target Neighborhood Hits	117	Shared Neighborhood Hits	84
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
NC score	0.583813 (rank : 39)	θ value	1.63604e-09 (rank : 71)
Query Neighborhood Hits	179	Target Neighborhood Hits	123	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

CI094_HUMAN
NC score	0.575801 (rank : 40)	θ value	1.52774e-15 (rank : 42)
Query Neighborhood Hits	179	Target Neighborhood Hits	310	Shared Neighborhood Hits	75
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ADAM8_HUMAN
NC score	0.550345 (rank : 41)	θ value	4.58923e-20 (rank : 39)
Query Neighborhood Hits	179	Target Neighborhood Hits	327	Shared Neighborhood Hits	87
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADA28_MOUSE
NC score	0.547663 (rank : 42)	θ value	3.51386e-20 (rank : 38)
Query Neighborhood Hits	179	Target Neighborhood Hits	241	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADAM8_MOUSE
NC score	0.547280 (rank : 43)	θ value	1.16975e-15 (rank : 41)
Query Neighborhood Hits	179	Target Neighborhood Hits	326	Shared Neighborhood Hits	91
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADA19_MOUSE
NC score	0.545881 (rank : 44)	θ value	2.06002e-20 (rank : 37)
Query Neighborhood Hits	179	Target Neighborhood Hits	315	Shared Neighborhood Hits	90
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA19_HUMAN
NC score	0.538414 (rank : 45)	θ value	1.86321e-21 (rank : 36)
Query Neighborhood Hits	179	Target Neighborhood Hits	381	Shared Neighborhood Hits	89
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA28_HUMAN
NC score	0.535086 (rank : 46)	θ value	2.7842e-17 (rank : 40)
Query Neighborhood Hits	179	Target Neighborhood Hits	244	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADEC1_HUMAN
NC score	0.532832 (rank : 47)	θ value	1.74796e-11 (rank : 63)
Query Neighborhood Hits	179	Target Neighborhood Hits	80	Shared Neighborhood Hits	71
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

THSD1_HUMAN
NC score	0.528546 (rank : 48)	θ value	9.92553e-07 (rank : 85)
Query Neighborhood Hits	179	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADA33_HUMAN
NC score	0.524156 (rank : 49)	θ value	4.59992e-12 (rank : 58)
Query Neighborhood Hits	179	Target Neighborhood Hits	264	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA12_HUMAN
NC score	0.523046 (rank : 50)	θ value	1.29331e-14 (rank : 44)
Query Neighborhood Hits	179	Target Neighborhood Hits	224	Shared Neighborhood Hits	83
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_MOUSE
NC score	0.514746 (rank : 51)	θ value	2.20605e-14 (rank : 46)
Query Neighborhood Hits	179	Target Neighborhood Hits	474	Shared Neighborhood Hits	92
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM7_HUMAN
NC score	0.511248 (rank : 52)	θ value	2.88119e-14 (rank : 47)
Query Neighborhood Hits	179	Target Neighborhood Hits	221	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
NC score	0.509139 (rank : 53)	θ value	4.16044e-13 (rank : 50)
Query Neighborhood Hits	179	Target Neighborhood Hits	200	Shared Neighborhood Hits	81
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADA15_HUMAN
NC score	0.501269 (rank : 54)	θ value	7.84624e-12 (rank : 60)
Query Neighborhood Hits	179	Target Neighborhood Hits	288	Shared Neighborhood Hits	87
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADAM9_MOUSE
NC score	0.500337 (rank : 55)	θ value	3.89403e-11 (rank : 65)
Query Neighborhood Hits	179	Target Neighborhood Hits	325	Shared Neighborhood Hits	85
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADA33_MOUSE
NC score	0.494685 (rank : 56)	θ value	1.06045e-08 (rank : 75)
Query Neighborhood Hits	179	Target Neighborhood Hits	231	Shared Neighborhood Hits	84
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

THSD1_MOUSE
NC score	0.494560 (rank : 57)	θ value	3.77169e-06 (rank : 91)
Query Neighborhood Hits	179	Target Neighborhood Hits	153	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADAM9_HUMAN
NC score	0.492478 (rank : 58)	θ value	7.09661e-13 (rank : 52)
Query Neighborhood Hits	179	Target Neighborhood Hits	243	Shared Neighborhood Hits	84
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADEC1_MOUSE
NC score	0.477632 (rank : 59)	θ value	4.92598e-06 (rank : 92)
Query Neighborhood Hits	179	Target Neighborhood Hits	85	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

UNC5A_MOUSE
NC score	0.472397 (rank : 60)	θ value	6.87365e-08 (rank : 80)
Query Neighborhood Hits	179	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

BAI2_HUMAN
NC score	0.471555 (rank : 61)	θ value	9.90251e-15 (rank : 43)
Query Neighborhood Hits	179	Target Neighborhood Hits	332	Shared Neighborhood Hits	87
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ADA15_MOUSE
NC score	0.470645 (rank : 62)	θ value	2.13673e-09 (rank : 72)
Query Neighborhood Hits	179	Target Neighborhood Hits	324	Shared Neighborhood Hits	92
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

BAI3_HUMAN
NC score	0.470346 (rank : 63)	θ value	6.41864e-14 (rank : 48)
Query Neighborhood Hits	179	Target Neighborhood Hits	246	Shared Neighborhood Hits	84
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

TSP1_HUMAN
NC score	0.470330 (rank : 64)	θ value	9.26847e-13 (rank : 53)
Query Neighborhood Hits	179	Target Neighborhood Hits	389	Shared Neighborhood Hits	96
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
NC score	0.469747 (rank : 65)	θ value	1.2105e-12 (rank : 54)
Query Neighborhood Hits	179	Target Neighborhood Hits	396	Shared Neighborhood Hits	98
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

BAI3_MOUSE
NC score	0.469142 (rank : 66)	θ value	2.43908e-13 (rank : 49)
Query Neighborhood Hits	179	Target Neighborhood Hits	250	Shared Neighborhood Hits	85
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI2_MOUSE
NC score	0.468921 (rank : 67)	θ value	1.68911e-14 (rank : 45)
Query Neighborhood Hits	179	Target Neighborhood Hits	323	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI1_MOUSE
NC score	0.468433 (rank : 68)	θ value	6.64225e-11 (rank : 66)
Query Neighborhood Hits	179	Target Neighborhood Hits	340	Shared Neighborhood Hits	86
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

TSP2_MOUSE
NC score	0.467294 (rank : 69)	θ value	6.00763e-12 (rank : 59)
Query Neighborhood Hits	179	Target Neighborhood Hits	352	Shared Neighborhood Hits	93
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

BAI1_HUMAN
NC score	0.466139 (rank : 70)	θ value	1.133e-10 (rank : 67)
Query Neighborhood Hits	179	Target Neighborhood Hits	375	Shared Neighborhood Hits	86
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

TSP2_HUMAN
NC score	0.463981 (rank : 71)	θ value	3.52202e-12 (rank : 57)
Query Neighborhood Hits	179	Target Neighborhood Hits	359	Shared Neighborhood Hits	94
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

UNC5B_MOUSE
NC score	0.462245 (rank : 72)	θ value	4.0297e-08 (rank : 78)
Query Neighborhood Hits	179	Target Neighborhood Hits	226	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

ADM1B_MOUSE
NC score	0.460183 (rank : 73)	θ value	0.000158464 (rank : 105)
Query Neighborhood Hits	179	Target Neighborhood Hits	236	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

UNC5B_HUMAN
NC score	0.459759 (rank : 74)	θ value	5.26297e-08 (rank : 79)
Query Neighborhood Hits	179	Target Neighborhood Hits	225	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

ADA21_MOUSE
NC score	0.458632 (rank : 75)	θ value	1.06045e-08 (rank : 74)
Query Neighborhood Hits	179	Target Neighborhood Hits	172	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
NC score	0.454954 (rank : 76)	θ value	3.19293e-05 (rank : 101)
Query Neighborhood Hits	179	Target Neighborhood Hits	211	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA24_MOUSE
NC score	0.452365 (rank : 77)	θ value	8.97725e-08 (rank : 81)
Query Neighborhood Hits	179	Target Neighborhood Hits	230	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADM1A_MOUSE
NC score	0.452242 (rank : 78)	θ value	9.29e-05 (rank : 102)
Query Neighborhood Hits	179	Target Neighborhood Hits	230	Shared Neighborhood Hits	84
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA29_HUMAN
NC score	0.449956 (rank : 79)	θ value	1.47974e-10 (rank : 69)
Query Neighborhood Hits	179	Target Neighborhood Hits	247	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA25_MOUSE
NC score	0.447102 (rank : 80)	θ value	1.53129e-07 (rank : 82)
Query Neighborhood Hits	179	Target Neighborhood Hits	213	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA22_MOUSE
NC score	0.445444 (rank : 81)	θ value	1.43324e-05 (rank : 96)
Query Neighborhood Hits	179	Target Neighborhood Hits	225	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_MOUSE
NC score	0.445032 (rank : 82)	θ value	0.000121331 (rank : 103)
Query Neighborhood Hits	179	Target Neighborhood Hits	245	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

UNC5C_MOUSE
NC score	0.444951 (rank : 83)	θ value	7.59969e-07 (rank : 84)
Query Neighborhood Hits	179	Target Neighborhood Hits	225	Shared Neighborhood Hits	77
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.444414 (rank : 84)	θ value	9.92553e-07 (rank : 86)
Query Neighborhood Hits	179	Target Neighborhood Hits	226	Shared Neighborhood Hits	77
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

ADA21_HUMAN
NC score	0.443628 (rank : 85)	θ value	1.29631e-06 (rank : 88)
Query Neighborhood Hits	179	Target Neighborhood Hits	181	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

AD26A_MOUSE
NC score	0.438185 (rank : 86)	θ value	6.43352e-06 (rank : 93)
Query Neighborhood Hits	179	Target Neighborhood Hits	165	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA23_HUMAN
NC score	0.437086 (rank : 87)	θ value	0.000158464 (rank : 104)
Query Neighborhood Hits	179	Target Neighborhood Hits	235	Shared Neighborhood Hits	83
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

SEM5A_HUMAN
NC score	0.436388 (rank : 88)	θ value	5.43371e-13 (rank : 51)
Query Neighborhood Hits	179	Target Neighborhood Hits	177	Shared Neighborhood Hits	84
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

UNC5D_HUMAN
NC score	0.436333 (rank : 89)	θ value	1.29631e-06 (rank : 89)
Query Neighborhood Hits	179	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

CO8A_HUMAN
NC score	0.434210 (rank : 90)	θ value	1.53129e-07 (rank : 83)
Query Neighborhood Hits	179	Target Neighborhood Hits	200	Shared Neighborhood Hits	73
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

UNC5D_MOUSE
NC score	0.432742 (rank : 91)	θ value	9.92553e-07 (rank : 87)
Query Neighborhood Hits	179	Target Neighborhood Hits	268	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

CO6_HUMAN
NC score	0.427427 (rank : 92)	θ value	3.08544e-08 (rank : 77)
Query Neighborhood Hits	179	Target Neighborhood Hits	331	Shared Neighborhood Hits	83
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

SEM5A_MOUSE
NC score	0.427257 (rank : 93)	θ value	2.69671e-12 (rank : 55)
Query Neighborhood Hits	179	Target Neighborhood Hits	162	Shared Neighborhood Hits	86
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ADA11_MOUSE
NC score	0.425645 (rank : 94)	θ value	2.44474e-05 (rank : 99)
Query Neighborhood Hits	179	Target Neighborhood Hits	263	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CO8A_MOUSE
NC score	0.425114 (rank : 95)	θ value	0.00020696 (rank : 106)
Query Neighborhood Hits	179	Target Neighborhood Hits	182	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

SEM5B_MOUSE
NC score	0.423327 (rank : 96)	θ value	2.98157e-11 (rank : 64)
Query Neighborhood Hits	179	Target Neighborhood Hits	190	Shared Neighborhood Hits	82
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5B_HUMAN
NC score	0.421783 (rank : 97)	θ value	1.33837e-11 (rank : 62)
Query Neighborhood Hits	179	Target Neighborhood Hits	178	Shared Neighborhood Hits	82
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

CILP2_HUMAN
NC score	0.420696 (rank : 98)	θ value	1.06045e-08 (rank : 76)
Query Neighborhood Hits	179	Target Neighborhood Hits	307	Shared Neighborhood Hits	75
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

SSPO_MOUSE
NC score	0.419920 (rank : 99)	θ value	5.62301e-10 (rank : 70)
Query Neighborhood Hits	179	Target Neighborhood Hits	800	Shared Neighborhood Hits	130
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CO8B_MOUSE
NC score	0.409874 (rank : 100)	θ value	1.09739e-05 (rank : 95)
Query Neighborhood Hits	179	Target Neighborhood Hits	224	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADA11_HUMAN
NC score	0.400995 (rank : 101)	θ value	0.000461057 (rank : 107)
Query Neighborhood Hits	179	Target Neighborhood Hits	259	Shared Neighborhood Hits	82
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA20_HUMAN
NC score	0.400442 (rank : 102)	θ value	0.00665767 (rank : 112)
Query Neighborhood Hits	179	Target Neighborhood Hits	143	Shared Neighborhood Hits	83
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADAM2_MOUSE
NC score	0.398365 (rank : 103)	θ value	0.00228821 (rank : 110)
Query Neighborhood Hits	179	Target Neighborhood Hits	209	Shared Neighborhood Hits	81
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADA32_HUMAN
NC score	0.392666 (rank : 104)	θ value	0.000786445 (rank : 108)
Query Neighborhood Hits	179	Target Neighborhood Hits	216	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
NC score	0.389412 (rank : 105)	θ value	0.00228821 (rank : 109)
Query Neighborhood Hits	179	Target Neighborhood Hits	219	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

UNC5A_HUMAN
NC score	0.387034 (rank : 106)	θ value	2.88788e-06 (rank : 90)
Query Neighborhood Hits	179	Target Neighborhood Hits	198	Shared Neighborhood Hits	73
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

CO7_HUMAN
NC score	0.379237 (rank : 107)	θ value	2.44474e-05 (rank : 100)
Query Neighborhood Hits	179	Target Neighborhood Hits	278	Shared Neighborhood Hits	75
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

ADA18_MOUSE
NC score	0.374590 (rank : 108)	θ value	0.00509761 (rank : 111)
Query Neighborhood Hits	179	Target Neighborhood Hits	227	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

CO8B_HUMAN
NC score	0.372755 (rank : 109)	θ value	6.43352e-06 (rank : 94)
Query Neighborhood Hits	179	Target Neighborhood Hits	199	Shared Neighborhood Hits	67
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADAM2_HUMAN
NC score	0.361413 (rank : 110)	θ value	0.125558 (rank : 116)
Query Neighborhood Hits	179	Target Neighborhood Hits	175	Shared Neighborhood Hits	78
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADA18_HUMAN
NC score	0.346439 (rank : 111)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	179	Target Neighborhood Hits	184	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA30_HUMAN
NC score	0.346269 (rank : 112)	θ value	0.00869519 (rank : 113)
Query Neighborhood Hits	179	Target Neighborhood Hits	391	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA10_MOUSE
NC score	0.342648 (rank : 113)	θ value	0.0736092 (rank : 114)
Query Neighborhood Hits	179	Target Neighborhood Hits	194	Shared Neighborhood Hits	80
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA17_MOUSE
NC score	0.342342 (rank : 114)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	179	Target Neighborhood Hits	201	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA10_HUMAN
NC score	0.339784 (rank : 115)	θ value	0.0961366 (rank : 115)
Query Neighborhood Hits	179	Target Neighborhood Hits	189	Shared Neighborhood Hits	81
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA17_HUMAN
NC score	0.331591 (rank : 116)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	179	Target Neighborhood Hits	223	Shared Neighborhood Hits	90
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

CILP1_MOUSE
NC score	0.313598 (rank : 117)	θ value	1.87187e-05 (rank : 98)
Query Neighborhood Hits	179	Target Neighborhood Hits	282	Shared Neighborhood Hits	75
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_HUMAN
NC score	0.312468 (rank : 118)	θ value	1.43324e-05 (rank : 97)
Query Neighborhood Hits	179	Target Neighborhood Hits	266	Shared Neighborhood Hits	76
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

HMCN1_HUMAN
NC score	0.286978 (rank : 119)	θ value	3.52202e-12 (rank : 56)
Query Neighborhood Hits	179	Target Neighborhood Hits	983	Shared Neighborhood Hits	112
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

WISP2_HUMAN
NC score	0.137696 (rank : 120)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	179	Target Neighborhood Hits	126	Shared Neighborhood Hits	60
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
NC score	0.134077 (rank : 121)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	179	Target Neighborhood Hits	129	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

WISP1_MOUSE
NC score	0.120396 (rank : 122)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	179	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP1_HUMAN
NC score	0.111266 (rank : 123)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	179	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

CYR61_HUMAN
NC score	0.107160 (rank : 124)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	179	Target Neighborhood Hits	159	Shared Neighborhood Hits	65
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

WISP3_HUMAN
NC score	0.101218 (rank : 125)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	179	Target Neighborhood Hits	87	Shared Neighborhood Hits	40
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

NOV_MOUSE
NC score	0.099001 (rank : 126)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	179	Target Neighborhood Hits	130	Shared Neighborhood Hits	51
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

CYR61_MOUSE
NC score	0.090105 (rank : 127)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	179	Target Neighborhood Hits	156	Shared Neighborhood Hits	56
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

FRAS1_MOUSE
NC score	0.088305 (rank : 128)	θ value	1.06291 (rank : 125)
Query Neighborhood Hits	179	Target Neighborhood Hits	747	Shared Neighborhood Hits	91
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NOV_HUMAN
NC score	0.086233 (rank : 129)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	179	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

CTGF_MOUSE
NC score	0.084652 (rank : 130)	θ value	0.47712 (rank : 119)
Query Neighborhood Hits	179	Target Neighborhood Hits	124	Shared Neighborhood Hits	46
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

KR106_HUMAN
NC score	0.083962 (rank : 131)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	179	Target Neighborhood Hits	347	Shared Neighborhood Hits	61
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

RSPO4_MOUSE
NC score	0.083895 (rank : 132)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	179	Target Neighborhood Hits	110	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RSPO1_HUMAN
NC score	0.081609 (rank : 133)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	179	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

CTGF_HUMAN
NC score	0.080742 (rank : 134)	θ value	1.06291 (rank : 124)
Query Neighborhood Hits	179	Target Neighborhood Hits	128	Shared Neighborhood Hits	48
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

KR104_HUMAN
NC score	0.080092 (rank : 135)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	179	Target Neighborhood Hits	313	Shared Neighborhood Hits	55
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

SPON2_HUMAN
NC score	0.078309 (rank : 136)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	179	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

FRAS1_HUMAN
NC score	0.073047 (rank : 137)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	179	Target Neighborhood Hits	759	Shared Neighborhood Hits	88
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CO9_MOUSE
NC score	0.072563 (rank : 138)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	179	Target Neighborhood Hits	153	Shared Neighborhood Hits	25
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

RSPO1_MOUSE
NC score	0.070281 (rank : 139)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	179	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

KR102_HUMAN
NC score	0.069903 (rank : 140)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	179	Target Neighborhood Hits	264	Shared Neighborhood Hits	47
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

SPON2_MOUSE
NC score	0.066366 (rank : 141)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	179	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

KRA98_HUMAN
NC score	0.065930 (rank : 142)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	179	Target Neighborhood Hits	185	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

CO9_HUMAN
NC score	0.065370 (rank : 143)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	179	Target Neighborhood Hits	147	Shared Neighborhood Hits	19
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

KR107_HUMAN
NC score	0.063994 (rank : 144)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	179	Target Neighborhood Hits	330	Shared Neighborhood Hits	49
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

RSPO4_HUMAN
NC score	0.062575 (rank : 145)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	179	Target Neighborhood Hits	110	Shared Neighborhood Hits	33
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

KRA92_HUMAN
NC score	0.061953 (rank : 146)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	179	Target Neighborhood Hits	198	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA51_HUMAN
NC score	0.061312 (rank : 147)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	179	Target Neighborhood Hits	288	Shared Neighborhood Hits	61
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA93_HUMAN
NC score	0.059684 (rank : 148)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	179	Target Neighborhood Hits	203	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

RSPO3_HUMAN
NC score	0.058248 (rank : 149)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	179	Target Neighborhood Hits	128	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

KRA53_HUMAN
NC score	0.056111 (rank : 150)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	179	Target Neighborhood Hits	331	Shared Neighborhood Hits	56
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

ZAN_MOUSE
NC score	0.055590 (rank : 151)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	179	Target Neighborhood Hits	808	Shared Neighborhood Hits	82
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KR101_HUMAN
NC score	0.054657 (rank : 152)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	179	Target Neighborhood Hits	261	Shared Neighborhood Hits	44
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

TENX_HUMAN
NC score	0.053501 (rank : 153)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	179	Target Neighborhood Hits	789	Shared Neighborhood Hits	82
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

KRA58_HUMAN
NC score	0.053123 (rank : 154)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	179	Target Neighborhood Hits	324	Shared Neighborhood Hits	55
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

RSPO3_MOUSE
NC score	0.052396 (rank : 155)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	179	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

KRA57_HUMAN
NC score	0.050224 (rank : 156)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	179	Target Neighborhood Hits	269	Shared Neighborhood Hits	47
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

COMP_HUMAN
NC score	0.050105 (rank : 157)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	179	Target Neighborhood Hits	258	Shared Neighborhood Hits	22
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

LRP1B_HUMAN
NC score	0.047044 (rank : 158)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	179	Target Neighborhood Hits	602	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MMP26_HUMAN
NC score	0.046643 (rank : 159)	θ value	0.813845 (rank : 122)
Query Neighborhood Hits	179	Target Neighborhood Hits	56	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

LRP1_HUMAN
NC score	0.045963 (rank : 160)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	179	Target Neighborhood Hits	617	Shared Neighborhood Hits	77
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

PCSK5_MOUSE
NC score	0.044415 (rank : 161)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	179	Target Neighborhood Hits	613	Shared Neighborhood Hits	65
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

RSPO2_MOUSE
NC score	0.040708 (rank : 162)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	179	Target Neighborhood Hits	88	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

FBN2_MOUSE
NC score	0.038376 (rank : 163)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	179	Target Neighborhood Hits	549	Shared Neighborhood Hits	72
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
NC score	0.037483 (rank : 164)	θ value	0.47712 (rank : 120)
Query Neighborhood Hits	179	Target Neighborhood Hits	560	Shared Neighborhood Hits	72
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

LRP8_MOUSE
NC score	0.031985 (rank : 165)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	179	Target Neighborhood Hits	385	Shared Neighborhood Hits	51
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
NC score	0.031584 (rank : 166)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	179	Target Neighborhood Hits	553	Shared Neighborhood Hits	61
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MMP2_HUMAN
NC score	0.031042 (rank : 167)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	179	Target Neighborhood Hits	79	Shared Neighborhood Hits	29
SwissProt Accessions	P08253	Gene names	MMP2, CLG4A
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A) (TBE- 1).

LTB1S_HUMAN
NC score	0.030036 (rank : 168)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	179	Target Neighborhood Hits	502	Shared Neighborhood Hits	58
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MMP2_MOUSE
NC score	0.029378 (rank : 169)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	179	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	P33434	Gene names	Mmp2
Domain Architecture
Description	72 kDa type IV collagenase precursor (EC 3.4.24.24) (72 kDa gelatinase) (Matrix metalloproteinase-2) (MMP-2) (Gelatinase A).

PAPD1_MOUSE
NC score	0.027102 (rank : 170)	θ value	0.125558 (rank : 117)
Query Neighborhood Hits	179	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0D3, Q3UXJ1, Q8C651	Gene names	Papd1
Domain Architecture	No domain graphic available
Description	Poly(A) RNA polymerase, mitochondrial precursor (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase) (PAP-associated domain-containing protein 1).

MMP9_MOUSE
NC score	0.021779 (rank : 171)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	179	Target Neighborhood Hits	151	Shared Neighborhood Hits	27
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

MMP21_MOUSE
NC score	0.020078 (rank : 172)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	179	Target Neighborhood Hits	59	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K3F2	Gene names	Mmp21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP1B_MOUSE
NC score	0.019723 (rank : 173)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	179	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

MMP9_HUMAN
NC score	0.018537 (rank : 174)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	179	Target Neighborhood Hits	125	Shared Neighborhood Hits	24
SwissProt Accessions	P14780, Q3LR70, Q8N725, Q9H4Z1	Gene names	MMP9, CLG4B
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB) [Contains: 67 kDa matrix metalloproteinase-9; 82 kDa matrix metalloproteinase-9].

ZNFX1_MOUSE
NC score	0.018108 (rank : 175)	θ value	0.62314 (rank : 121)
Query Neighborhood Hits	179	Target Neighborhood Hits	407	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

MMP24_MOUSE
NC score	0.017575 (rank : 176)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	179	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R0S2, Q9Z0J9	Gene names	Mmp24, Mmp21, Mt5mmp
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP) (MMP-21).

MMP11_HUMAN
NC score	0.017359 (rank : 177)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	179	Target Neighborhood Hits	65	Shared Neighborhood Hits	27
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP21_HUMAN
NC score	0.016428 (rank : 178)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	179	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

MMP1A_MOUSE
NC score	0.016200 (rank : 179)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	179	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EPL5	Gene names	Mmp1a, McolA
Domain Architecture	No domain graphic available
Description	Interstitial collagenase A precursor (EC 3.4.24.7) (Matrix metalloproteinase-1a) (MMP-1a) (Mcol-A).

MMP14_HUMAN
NC score	0.016129 (rank : 180)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	179	Target Neighborhood Hits	60	Shared Neighborhood Hits	25
SwissProt Accessions	P50281, Q92678	Gene names	MMP14
Domain Architecture
Description	Matrix metalloproteinase-14 precursor (EC 3.4.24.80) (MMP-14) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP) (MMP- X1).

VOME_MOUSE
NC score	0.016114 (rank : 181)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	179	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XI7, Q5XK13, Q8CDY1	Gene names
Domain Architecture	No domain graphic available
Description	Vomeromodulin precursor.

MMP24_HUMAN
NC score	0.015889 (rank : 182)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	179	Target Neighborhood Hits	66	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5R2, Q9H440	Gene names	MMP24, MT5MMP
Domain Architecture
Description	Matrix metalloproteinase-24 precursor (EC 3.4.24.-) (MMP-24) (Membrane-type matrix metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix metalloproteinase) (MT5-MMP).

MMP15_MOUSE
NC score	0.015515 (rank : 183)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	179	Target Neighborhood Hits	102	Shared Neighborhood Hits	22
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

MMP16_MOUSE
NC score	0.014517 (rank : 184)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	179	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WTR0, Q9ERT6	Gene names	Mmp16
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP).

MMP16_HUMAN
NC score	0.014494 (rank : 185)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	179	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	P51512, Q14824, Q52H48	Gene names	MMP16, MMPX2
Domain Architecture
Description	Matrix metalloproteinase-16 precursor (EC 3.4.24.-) (MMP-16) (Membrane-type matrix metalloproteinase 3) (MT-MMP 3) (MTMMP3) (Membrane-type-3 matrix metalloproteinase) (MT3-MMP) (MT3MMP) (MMP- X2).

PRG4_MOUSE
NC score	0.012532 (rank : 186)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	179	Target Neighborhood Hits	624	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

FAS_MOUSE
NC score	0.010408 (rank : 187)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	179	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	P19096, Q6PB72, Q8C4Z0, Q9EQR0	Gene names	Fasn
Domain Architecture	No domain graphic available
Description	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S- malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)].

IBP4_HUMAN
NC score	0.009829 (rank : 188)	θ value	1.06291 (rank : 126)
Query Neighborhood Hits	179	Target Neighborhood Hits	52	Shared Neighborhood Hits	5
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

CFAI_HUMAN
NC score	0.009778 (rank : 189)	θ value	0.163984 (rank : 118)
Query Neighborhood Hits	179	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CPSF7_MOUSE
NC score	0.006781 (rank : 190)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	179	Target Neighborhood Hits	123	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

CS007_MOUSE
NC score	0.006780 (rank : 191)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	179	Target Neighborhood Hits	464	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

IBP4_MOUSE
NC score	0.006708 (rank : 192)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	179	Target Neighborhood Hits	55	Shared Neighborhood Hits	5
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

CPSF7_HUMAN
NC score	0.006152 (rank : 193)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	179	Target Neighborhood Hits	125	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N684, Q7Z3H9, Q9H025, Q9H9V1	Gene names	CPSF7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7 (Cleavage and polyadenylation specificity factor 59 kDa subunit) (CPSF 59 kDa subunit) (Pre-mRNA cleavage factor Im 59 kDa subunit).

G3BP2_HUMAN
NC score	0.006073 (rank : 194)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	179	Target Neighborhood Hits	260	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

SYMM_MOUSE
NC score	0.005713 (rank : 195)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	179	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

BTBDA_HUMAN
NC score	0.005658 (rank : 196)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	179	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BSF8, Q86WG1	Gene names	BTBD10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 10.

UBE4B_HUMAN
NC score	0.005643 (rank : 197)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	179	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

G3BP2_MOUSE
NC score	0.005240 (rank : 198)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	179	Target Neighborhood Hits	258	Shared Neighborhood Hits	3
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

NMDE3_HUMAN
NC score	0.004553 (rank : 199)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	179	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q14957	Gene names	GRIN2C
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl D- aspartate receptor subtype 2C) (NR2C) (NMDAR2C).

PCLO_MOUSE
NC score	0.004174 (rank : 200)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	179	Target Neighborhood Hits	2275	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TRIM1_HUMAN
NC score	0.003825 (rank : 201)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	179	Target Neighborhood Hits	345	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI18_MOUSE
NC score	0.003072 (rank : 202)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	179	Target Neighborhood Hits	292	Shared Neighborhood Hits	4
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI18_HUMAN
NC score	0.002837 (rank : 203)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	179	Target Neighborhood Hits	307	Shared Neighborhood Hits	4
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

CAN12_MOUSE
NC score	0.001392 (rank : 204)	θ value	5.27518 (rank : 148)
Query Neighborhood Hits	179	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ER56, Q9ER53, Q9ER54, Q9ER55	Gene names	Capn12
Domain Architecture
Description	Calpain-12 (EC 3.4.22.-).

SOX13_HUMAN
NC score	-0.001429 (rank : 205)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	179	Target Neighborhood Hits	464	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

ZN221_HUMAN
NC score	-0.007461 (rank : 206)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	179	Target Neighborhood Hits	784	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UK13, Q9P1U8	Gene names	ZNF221
Domain Architecture
Description	Zinc finger protein 221.

O2T34_HUMAN
NC score	-0.008100 (rank : 207)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	179	Target Neighborhood Hits	863	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGX1, Q6IEY5, Q96R31	Gene names	OR2T34
Domain Architecture	No domain graphic available
Description	Olfactory receptor 2T34 (Olfactory receptor OR1-63).