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Network neighborhood for query Sequence : ATS12_HUMAN

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ATS12_HUMAN
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ATS12_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	251	Target Neighborhood Hits	251	Shared Neighborhood Hits	251
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_MOUSE
θ value	0 (rank : 2)	NC score	0.994926 (rank : 2)
Query Neighborhood Hits	251	Target Neighborhood Hits	220	Shared Neighborhood Hits	158
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS18_HUMAN
θ value	0 (rank : 3)	NC score	0.979052 (rank : 4)
Query Neighborhood Hits	251	Target Neighborhood Hits	169	Shared Neighborhood Hits	136
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS7_HUMAN
θ value	0 (rank : 4)	NC score	0.984404 (rank : 3)
Query Neighborhood Hits	251	Target Neighborhood Hits	169	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS18_MOUSE
θ value	3.82926e-184 (rank : 5)	NC score	0.978484 (rank : 5)
Query Neighborhood Hits	251	Target Neighborhood Hits	163	Shared Neighborhood Hits	137
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_HUMAN
θ value	1.50931e-172 (rank : 6)	NC score	0.976829 (rank : 7)
Query Neighborhood Hits	251	Target Neighborhood Hits	208	Shared Neighborhood Hits	142
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_MOUSE
θ value	2.57449e-172 (rank : 7)	NC score	0.977625 (rank : 6)
Query Neighborhood Hits	251	Target Neighborhood Hits	179	Shared Neighborhood Hits	139
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS19_HUMAN
θ value	6.80647e-157 (rank : 8)	NC score	0.968380 (rank : 13)
Query Neighborhood Hits	251	Target Neighborhood Hits	203	Shared Neighborhood Hits	130
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS6_HUMAN
θ value	5.3931e-154 (rank : 9)	NC score	0.975731 (rank : 8)
Query Neighborhood Hits	251	Target Neighborhood Hits	141	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS19_MOUSE
θ value	9.19922e-154 (rank : 10)	NC score	0.969494 (rank : 11)
Query Neighborhood Hits	251	Target Neighborhood Hits	188	Shared Neighborhood Hits	130
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS20_HUMAN
θ value	7.28896e-151 (rank : 11)	NC score	0.968633 (rank : 12)
Query Neighborhood Hits	251	Target Neighborhood Hits	192	Shared Neighborhood Hits	135
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	1.24331e-150 (rank : 12)	NC score	0.967907 (rank : 14)
Query Neighborhood Hits	251	Target Neighborhood Hits	225	Shared Neighborhood Hits	138
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS9_HUMAN
θ value	2.34478e-149 (rank : 13)	NC score	0.966812 (rank : 16)
Query Neighborhood Hits	251	Target Neighborhood Hits	219	Shared Neighborhood Hits	141
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS17_HUMAN
θ value	1.33145e-144 (rank : 14)	NC score	0.974003 (rank : 9)
Query Neighborhood Hits	251	Target Neighborhood Hits	194	Shared Neighborhood Hits	136
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS3_HUMAN
θ value	4.29305e-135 (rank : 15)	NC score	0.969545 (rank : 10)
Query Neighborhood Hits	251	Target Neighborhood Hits	179	Shared Neighborhood Hits	135
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS1_MOUSE
θ value	4.74654e-134 (rank : 16)	NC score	0.966211 (rank : 17)
Query Neighborhood Hits	251	Target Neighborhood Hits	158	Shared Neighborhood Hits	133
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS1_HUMAN
θ value	9.92011e-124 (rank : 17)	NC score	0.964575 (rank : 20)
Query Neighborhood Hits	251	Target Neighborhood Hits	159	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS2_HUMAN
θ value	7.86017e-121 (rank : 18)	NC score	0.964939 (rank : 18)
Query Neighborhood Hits	251	Target Neighborhood Hits	179	Shared Neighborhood Hits	129
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
θ value	1.34075e-120 (rank : 19)	NC score	0.964744 (rank : 19)
Query Neighborhood Hits	251	Target Neighborhood Hits	179	Shared Neighborhood Hits	129
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS15_HUMAN
θ value	8.69046e-120 (rank : 20)	NC score	0.967469 (rank : 15)
Query Neighborhood Hits	251	Target Neighborhood Hits	151	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS14_HUMAN
θ value	4.03687e-117 (rank : 21)	NC score	0.959357 (rank : 24)
Query Neighborhood Hits	251	Target Neighborhood Hits	382	Shared Neighborhood Hits	135
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS8_HUMAN
θ value	8.71062e-112 (rank : 22)	NC score	0.961151 (rank : 22)
Query Neighborhood Hits	251	Target Neighborhood Hits	145	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS5_MOUSE
θ value	3.31772e-103 (rank : 23)	NC score	0.962080 (rank : 21)
Query Neighborhood Hits	251	Target Neighborhood Hits	147	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS13_HUMAN
θ value	2.15048e-102 (rank : 24)	NC score	0.933467 (rank : 28)
Query Neighborhood Hits	251	Target Neighborhood Hits	238	Shared Neighborhood Hits	116
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS5_HUMAN
θ value	1.3939e-101 (rank : 25)	NC score	0.959735 (rank : 23)
Query Neighborhood Hits	251	Target Neighborhood Hits	141	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS8_MOUSE
θ value	6.91785e-101 (rank : 26)	NC score	0.953434 (rank : 25)
Query Neighborhood Hits	251	Target Neighborhood Hits	139	Shared Neighborhood Hits	115
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS13_MOUSE
θ value	5.85632e-100 (rank : 27)	NC score	0.932223 (rank : 29)
Query Neighborhood Hits	251	Target Neighborhood Hits	227	Shared Neighborhood Hits	123
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS4_MOUSE
θ value	9.98939e-100 (rank : 28)	NC score	0.947124 (rank : 26)
Query Neighborhood Hits	251	Target Neighborhood Hits	145	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS4_HUMAN
θ value	1.44246e-98 (rank : 29)	NC score	0.945624 (rank : 27)
Query Neighborhood Hits	251	Target Neighborhood Hits	138	Shared Neighborhood Hits	113
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATL3_HUMAN
θ value	4.53632e-60 (rank : 30)	NC score	0.751390 (rank : 35)
Query Neighborhood Hits	251	Target Neighborhood Hits	414	Shared Neighborhood Hits	101
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATL1_HUMAN
θ value	5.19021e-56 (rank : 31)	NC score	0.889345 (rank : 31)
Query Neighborhood Hits	251	Target Neighborhood Hits	93	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL2_HUMAN
θ value	3.04986e-48 (rank : 32)	NC score	0.859303 (rank : 34)
Query Neighborhood Hits	251	Target Neighborhood Hits	125	Shared Neighborhood Hits	86
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	1.15895e-47 (rank : 33)	NC score	0.859896 (rank : 33)
Query Neighborhood Hits	251	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL1_MOUSE
θ value	7.77379e-44 (rank : 34)	NC score	0.882483 (rank : 32)
Query Neighborhood Hits	251	Target Neighborhood Hits	80	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL5_HUMAN
θ value	1.46607e-42 (rank : 35)	NC score	0.892735 (rank : 30)
Query Neighborhood Hits	251	Target Neighborhood Hits	103	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

CI094_HUMAN
θ value	8.91499e-32 (rank : 36)	NC score	0.577568 (rank : 48)
Query Neighborhood Hits	251	Target Neighborhood Hits	310	Shared Neighborhood Hits	77
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ADA28_HUMAN
θ value	1.47289e-26 (rank : 37)	NC score	0.588293 (rank : 42)
Query Neighborhood Hits	251	Target Neighborhood Hits	244	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA28_MOUSE
θ value	1.24688e-25 (rank : 38)	NC score	0.598347 (rank : 40)
Query Neighborhood Hits	251	Target Neighborhood Hits	241	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADAM8_MOUSE
θ value	7.56453e-23 (rank : 39)	NC score	0.599358 (rank : 38)
Query Neighborhood Hits	251	Target Neighborhood Hits	326	Shared Neighborhood Hits	108
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADA19_HUMAN
θ value	1.09232e-21 (rank : 40)	NC score	0.587829 (rank : 43)
Query Neighborhood Hits	251	Target Neighborhood Hits	381	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA12_HUMAN
θ value	2.69047e-20 (rank : 41)	NC score	0.578158 (rank : 46)
Query Neighborhood Hits	251	Target Neighborhood Hits	224	Shared Neighborhood Hits	80
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM8_HUMAN
θ value	3.51386e-20 (rank : 42)	NC score	0.598467 (rank : 39)
Query Neighborhood Hits	251	Target Neighborhood Hits	327	Shared Neighborhood Hits	99
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM9_MOUSE
θ value	7.82807e-20 (rank : 43)	NC score	0.559364 (rank : 53)
Query Neighborhood Hits	251	Target Neighborhood Hits	325	Shared Neighborhood Hits	93
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADA12_MOUSE
θ value	1.33526e-19 (rank : 44)	NC score	0.569756 (rank : 50)
Query Neighborhood Hits	251	Target Neighborhood Hits	474	Shared Neighborhood Hits	89
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM7_MOUSE
θ value	1.92812e-18 (rank : 45)	NC score	0.563071 (rank : 52)
Query Neighborhood Hits	251	Target Neighborhood Hits	200	Shared Neighborhood Hits	80
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM7_HUMAN
θ value	7.32683e-18 (rank : 46)	NC score	0.564571 (rank : 51)
Query Neighborhood Hits	251	Target Neighborhood Hits	221	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADA19_MOUSE
θ value	1.24977e-17 (rank : 47)	NC score	0.594104 (rank : 41)
Query Neighborhood Hits	251	Target Neighborhood Hits	315	Shared Neighborhood Hits	90
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

HMCN1_HUMAN
θ value	2.13179e-17 (rank : 48)	NC score	0.285715 (rank : 117)
Query Neighborhood Hits	251	Target Neighborhood Hits	983	Shared Neighborhood Hits	120
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

TSP1_HUMAN
θ value	1.38178e-16 (rank : 49)	NC score	0.468413 (rank : 74)
Query Neighborhood Hits	251	Target Neighborhood Hits	389	Shared Neighborhood Hits	110
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ADA33_HUMAN
θ value	1.80466e-16 (rank : 50)	NC score	0.576022 (rank : 49)
Query Neighborhood Hits	251	Target Neighborhood Hits	264	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

TSP1_MOUSE
θ value	4.02038e-16 (rank : 51)	NC score	0.467505 (rank : 75)
Query Neighborhood Hits	251	Target Neighborhood Hits	396	Shared Neighborhood Hits	111
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

ADM1A_MOUSE
θ value	8.95645e-16 (rank : 52)	NC score	0.520216 (rank : 60)
Query Neighborhood Hits	251	Target Neighborhood Hits	230	Shared Neighborhood Hits	91
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

SSPO_MOUSE
θ value	8.95645e-16 (rank : 53)	NC score	0.426404 (rank : 97)
Query Neighborhood Hits	251	Target Neighborhood Hits	800	Shared Neighborhood Hits	151
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ADAM9_HUMAN
θ value	1.16975e-15 (rank : 54)	NC score	0.549093 (rank : 56)
Query Neighborhood Hits	251	Target Neighborhood Hits	243	Shared Neighborhood Hits	85
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

AD26A_MOUSE
θ value	1.52774e-15 (rank : 55)	NC score	0.504648 (rank : 70)
Query Neighborhood Hits	251	Target Neighborhood Hits	165	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADM1B_MOUSE
θ value	9.90251e-15 (rank : 56)	NC score	0.527061 (rank : 59)
Query Neighborhood Hits	251	Target Neighborhood Hits	236	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

TSP2_HUMAN
θ value	9.90251e-15 (rank : 57)	NC score	0.462768 (rank : 80)
Query Neighborhood Hits	251	Target Neighborhood Hits	359	Shared Neighborhood Hits	115
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

SEM5A_HUMAN
θ value	2.20605e-14 (rank : 58)	NC score	0.429577 (rank : 96)
Query Neighborhood Hits	251	Target Neighborhood Hits	177	Shared Neighborhood Hits	87
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	2.88119e-14 (rank : 59)	NC score	0.420821 (rank : 100)
Query Neighborhood Hits	251	Target Neighborhood Hits	162	Shared Neighborhood Hits	88
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

TSP2_MOUSE
θ value	3.76295e-14 (rank : 60)	NC score	0.464612 (rank : 77)
Query Neighborhood Hits	251	Target Neighborhood Hits	352	Shared Neighborhood Hits	110
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADA23_MOUSE
θ value	1.09485e-13 (rank : 61)	NC score	0.509996 (rank : 65)
Query Neighborhood Hits	251	Target Neighborhood Hits	245	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA22_HUMAN
θ value	1.42992e-13 (rank : 62)	NC score	0.518419 (rank : 62)
Query Neighborhood Hits	251	Target Neighborhood Hits	211	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

BAI2_HUMAN
θ value	2.43908e-13 (rank : 63)	NC score	0.459950 (rank : 81)
Query Neighborhood Hits	251	Target Neighborhood Hits	332	Shared Neighborhood Hits	94
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ADA15_MOUSE
θ value	3.18553e-13 (rank : 64)	NC score	0.528134 (rank : 57)
Query Neighborhood Hits	251	Target Neighborhood Hits	324	Shared Neighborhood Hits	93
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

BAI3_HUMAN
θ value	4.16044e-13 (rank : 65)	NC score	0.456482 (rank : 87)
Query Neighborhood Hits	251	Target Neighborhood Hits	246	Shared Neighborhood Hits	90
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

ADA21_MOUSE
θ value	5.43371e-13 (rank : 66)	NC score	0.519020 (rank : 61)
Query Neighborhood Hits	251	Target Neighborhood Hits	172	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA15_HUMAN
θ value	9.26847e-13 (rank : 67)	NC score	0.554926 (rank : 54)
Query Neighborhood Hits	251	Target Neighborhood Hits	288	Shared Neighborhood Hits	95
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

BAI2_MOUSE
θ value	1.2105e-12 (rank : 68)	NC score	0.457573 (rank : 84)
Query Neighborhood Hits	251	Target Neighborhood Hits	323	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ADA21_HUMAN
θ value	1.58096e-12 (rank : 69)	NC score	0.505153 (rank : 69)
Query Neighborhood Hits	251	Target Neighborhood Hits	181	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

SEM5B_HUMAN
θ value	1.58096e-12 (rank : 70)	NC score	0.414958 (rank : 104)
Query Neighborhood Hits	251	Target Neighborhood Hits	178	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SEM5B_MOUSE
θ value	1.58096e-12 (rank : 71)	NC score	0.416780 (rank : 103)
Query Neighborhood Hits	251	Target Neighborhood Hits	190	Shared Neighborhood Hits	88
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

BAI3_MOUSE
θ value	2.0648e-12 (rank : 72)	NC score	0.455515 (rank : 89)
Query Neighborhood Hits	251	Target Neighborhood Hits	250	Shared Neighborhood Hits	92
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

ADA23_HUMAN
θ value	4.59992e-12 (rank : 73)	NC score	0.501584 (rank : 71)
Query Neighborhood Hits	251	Target Neighborhood Hits	235	Shared Neighborhood Hits	79
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA33_MOUSE
θ value	1.02475e-11 (rank : 74)	NC score	0.549481 (rank : 55)
Query Neighborhood Hits	251	Target Neighborhood Hits	231	Shared Neighborhood Hits	86
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

PROP_MOUSE
θ value	1.33837e-11 (rank : 75)	NC score	0.622381 (rank : 37)
Query Neighborhood Hits	251	Target Neighborhood Hits	165	Shared Neighborhood Hits	86
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

ADA24_MOUSE
θ value	2.28291e-11 (rank : 76)	NC score	0.512923 (rank : 63)
Query Neighborhood Hits	251	Target Neighborhood Hits	230	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

SPON1_HUMAN
θ value	3.89403e-11 (rank : 77)	NC score	0.580450 (rank : 44)
Query Neighborhood Hits	251	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

PROP_HUMAN
θ value	6.64225e-11 (rank : 78)	NC score	0.629001 (rank : 36)
Query Neighborhood Hits	251	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

ADA22_MOUSE
θ value	8.67504e-11 (rank : 79)	NC score	0.508452 (rank : 66)
Query Neighborhood Hits	251	Target Neighborhood Hits	225	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA29_HUMAN
θ value	1.133e-10 (rank : 80)	NC score	0.507563 (rank : 67)
Query Neighborhood Hits	251	Target Neighborhood Hits	247	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

SPON1_MOUSE
θ value	1.47974e-10 (rank : 81)	NC score	0.578090 (rank : 47)
Query Neighborhood Hits	251	Target Neighborhood Hits	123	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

ADEC1_HUMAN
θ value	1.9326e-10 (rank : 82)	NC score	0.578237 (rank : 45)
Query Neighborhood Hits	251	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

BAI1_HUMAN
θ value	9.59137e-10 (rank : 83)	NC score	0.455661 (rank : 88)
Query Neighborhood Hits	251	Target Neighborhood Hits	375	Shared Neighborhood Hits	96
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	9.59137e-10 (rank : 84)	NC score	0.457692 (rank : 83)
Query Neighborhood Hits	251	Target Neighborhood Hits	340	Shared Neighborhood Hits	99
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ADA11_MOUSE
θ value	2.13673e-09 (rank : 85)	NC score	0.489111 (rank : 72)
Query Neighborhood Hits	251	Target Neighborhood Hits	263	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA25_MOUSE
θ value	2.79066e-09 (rank : 86)	NC score	0.505599 (rank : 68)
Query Neighborhood Hits	251	Target Neighborhood Hits	213	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA32_MOUSE
θ value	2.79066e-09 (rank : 87)	NC score	0.456625 (rank : 86)
Query Neighborhood Hits	251	Target Neighborhood Hits	219	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

UNC5A_MOUSE
θ value	1.80886e-08 (rank : 88)	NC score	0.459779 (rank : 82)
Query Neighborhood Hits	251	Target Neighborhood Hits	203	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	3.08544e-08 (rank : 89)	NC score	0.446909 (rank : 91)
Query Neighborhood Hits	251	Target Neighborhood Hits	225	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	3.08544e-08 (rank : 90)	NC score	0.449227 (rank : 90)
Query Neighborhood Hits	251	Target Neighborhood Hits	226	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

ADA20_HUMAN
θ value	5.26297e-08 (rank : 91)	NC score	0.464452 (rank : 78)
Query Neighborhood Hits	251	Target Neighborhood Hits	143	Shared Neighborhood Hits	79
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADAM2_MOUSE
θ value	5.26297e-08 (rank : 92)	NC score	0.464098 (rank : 79)
Query Neighborhood Hits	251	Target Neighborhood Hits	209	Shared Neighborhood Hits	83
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

UNC5C_HUMAN
θ value	6.87365e-08 (rank : 93)	NC score	0.433120 (rank : 94)
Query Neighborhood Hits	251	Target Neighborhood Hits	226	Shared Neighborhood Hits	79
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	6.87365e-08 (rank : 94)	NC score	0.433486 (rank : 93)
Query Neighborhood Hits	251	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

ADA18_HUMAN
θ value	8.97725e-08 (rank : 95)	NC score	0.417793 (rank : 102)
Query Neighborhood Hits	251	Target Neighborhood Hits	184	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

CO6_HUMAN
θ value	1.17247e-07 (rank : 96)	NC score	0.413630 (rank : 105)
Query Neighborhood Hits	251	Target Neighborhood Hits	331	Shared Neighborhood Hits	83
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

ADAM2_HUMAN
θ value	1.99992e-07 (rank : 97)	NC score	0.429610 (rank : 95)
Query Neighborhood Hits	251	Target Neighborhood Hits	175	Shared Neighborhood Hits	74
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

CO7_HUMAN
θ value	1.99992e-07 (rank : 98)	NC score	0.372540 (rank : 114)
Query Neighborhood Hits	251	Target Neighborhood Hits	278	Shared Neighborhood Hits	72
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

ADA11_HUMAN
θ value	3.41135e-07 (rank : 99)	NC score	0.464986 (rank : 76)
Query Neighborhood Hits	251	Target Neighborhood Hits	259	Shared Neighborhood Hits	77
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

UNC5D_HUMAN
θ value	3.41135e-07 (rank : 100)	NC score	0.425514 (rank : 98)
Query Neighborhood Hits	251	Target Neighborhood Hits	267	Shared Neighborhood Hits	77
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	3.41135e-07 (rank : 101)	NC score	0.421937 (rank : 99)
Query Neighborhood Hits	251	Target Neighborhood Hits	268	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

THSD1_HUMAN
θ value	1.29631e-06 (rank : 102)	NC score	0.510446 (rank : 64)
Query Neighborhood Hits	251	Target Neighborhood Hits	136	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADA32_HUMAN
θ value	1.69304e-06 (rank : 103)	NC score	0.456991 (rank : 85)
Query Neighborhood Hits	251	Target Neighborhood Hits	216	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA18_MOUSE
θ value	2.21117e-06 (rank : 104)	NC score	0.440553 (rank : 92)
Query Neighborhood Hits	251	Target Neighborhood Hits	227	Shared Neighborhood Hits	91
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

CO8A_MOUSE
θ value	2.21117e-06 (rank : 105)	NC score	0.413094 (rank : 106)
Query Neighborhood Hits	251	Target Neighborhood Hits	182	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_HUMAN
θ value	1.87187e-05 (rank : 106)	NC score	0.418519 (rank : 101)
Query Neighborhood Hits	251	Target Neighborhood Hits	200	Shared Neighborhood Hits	73
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ADA30_HUMAN
θ value	2.44474e-05 (rank : 107)	NC score	0.407295 (rank : 107)
Query Neighborhood Hits	251	Target Neighborhood Hits	391	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

THSD1_MOUSE
θ value	5.44631e-05 (rank : 108)	NC score	0.477366 (rank : 73)
Query Neighborhood Hits	251	Target Neighborhood Hits	153	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADEC1_MOUSE
θ value	0.000121331 (rank : 109)	NC score	0.528086 (rank : 58)
Query Neighborhood Hits	251	Target Neighborhood Hits	85	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

CO8B_MOUSE
θ value	0.000121331 (rank : 110)	NC score	0.393100 (rank : 109)
Query Neighborhood Hits	251	Target Neighborhood Hits	224	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_HUMAN
θ value	0.000461057 (rank : 111)	NC score	0.357276 (rank : 116)
Query Neighborhood Hits	251	Target Neighborhood Hits	199	Shared Neighborhood Hits	67
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ADA17_MOUSE
θ value	0.00228821 (rank : 112)	NC score	0.393168 (rank : 108)
Query Neighborhood Hits	251	Target Neighborhood Hits	201	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

MAGE1_HUMAN
θ value	0.00228821 (rank : 113)	NC score	0.012962 (rank : 208)
Query Neighborhood Hits	251	Target Neighborhood Hits	1389	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

UNC5A_HUMAN
θ value	0.00228821 (rank : 114)	NC score	0.371121 (rank : 115)
Query Neighborhood Hits	251	Target Neighborhood Hits	198	Shared Neighborhood Hits	75
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

MDC1_HUMAN
θ value	0.00298849 (rank : 115)	NC score	0.017191 (rank : 200)
Query Neighborhood Hits	251	Target Neighborhood Hits	1446	Shared Neighborhood Hits	40
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CILP2_HUMAN
θ value	0.00665767 (rank : 116)	NC score	0.386538 (rank : 110)
Query Neighborhood Hits	251	Target Neighborhood Hits	307	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

NACAM_MOUSE
θ value	0.00665767 (rank : 117)	NC score	0.020692 (rank : 194)
Query Neighborhood Hits	251	Target Neighborhood Hits	1866	Shared Neighborhood Hits	57
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CILP1_HUMAN
θ value	0.00869519 (rank : 118)	NC score	0.283088 (rank : 119)
Query Neighborhood Hits	251	Target Neighborhood Hits	266	Shared Neighborhood Hits	78
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

SPESP_MOUSE
θ value	0.0113563 (rank : 119)	NC score	0.036952 (rank : 185)
Query Neighborhood Hits	251	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.

SYNJ2_MOUSE
θ value	0.0148317 (rank : 120)	NC score	0.016727 (rank : 201)
Query Neighborhood Hits	251	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

CILP1_MOUSE
θ value	0.0193708 (rank : 121)	NC score	0.283692 (rank : 118)
Query Neighborhood Hits	251	Target Neighborhood Hits	282	Shared Neighborhood Hits	78
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

NOV_HUMAN
θ value	0.0252991 (rank : 122)	NC score	0.119538 (rank : 128)
Query Neighborhood Hits	251	Target Neighborhood Hits	128	Shared Neighborhood Hits	58
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

RSPO4_MOUSE
θ value	0.0252991 (rank : 123)	NC score	0.099407 (rank : 133)
Query Neighborhood Hits	251	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

ADA17_HUMAN
θ value	0.0431538 (rank : 124)	NC score	0.379060 (rank : 111)
Query Neighborhood Hits	251	Target Neighborhood Hits	223	Shared Neighborhood Hits	84
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

GMEB2_HUMAN
θ value	0.0563607 (rank : 125)	NC score	0.025964 (rank : 189)
Query Neighborhood Hits	251	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

CRIM1_HUMAN
θ value	0.0736092 (rank : 126)	NC score	0.065920 (rank : 151)
Query Neighborhood Hits	251	Target Neighborhood Hits	362	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

NOV_MOUSE
θ value	0.0961366 (rank : 127)	NC score	0.132524 (rank : 125)
Query Neighborhood Hits	251	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

CTGF_MOUSE
θ value	0.125558 (rank : 128)	NC score	0.112814 (rank : 129)
Query Neighborhood Hits	251	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

GMEB2_MOUSE
θ value	0.125558 (rank : 129)	NC score	0.024838 (rank : 190)
Query Neighborhood Hits	251	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

TJAP1_MOUSE
θ value	0.125558 (rank : 130)	NC score	0.017516 (rank : 198)
Query Neighborhood Hits	251	Target Neighborhood Hits	295	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

WISP1_MOUSE
θ value	0.125558 (rank : 131)	NC score	0.152479 (rank : 122)
Query Neighborhood Hits	251	Target Neighborhood Hits	123	Shared Neighborhood Hits	61
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

CYR61_HUMAN
θ value	0.163984 (rank : 132)	NC score	0.136116 (rank : 124)
Query Neighborhood Hits	251	Target Neighborhood Hits	159	Shared Neighborhood Hits	69
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

FRAS1_MOUSE
θ value	0.163984 (rank : 133)	NC score	0.100082 (rank : 132)
Query Neighborhood Hits	251	Target Neighborhood Hits	747	Shared Neighborhood Hits	109
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

WISP1_HUMAN
θ value	0.21417 (rank : 134)	NC score	0.145315 (rank : 123)
Query Neighborhood Hits	251	Target Neighborhood Hits	121	Shared Neighborhood Hits	64
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

EMIL3_HUMAN
θ value	0.279714 (rank : 135)	NC score	0.015060 (rank : 205)
Query Neighborhood Hits	251	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

EMIL3_MOUSE
θ value	0.279714 (rank : 136)	NC score	0.015189 (rank : 204)
Query Neighborhood Hits	251	Target Neighborhood Hits	240	Shared Neighborhood Hits	6
SwissProt Accessions	P59900	Gene names	Emilin3, Emilin5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5).

GP1BA_HUMAN
θ value	0.279714 (rank : 137)	NC score	0.004390 (rank : 255)
Query Neighborhood Hits	251	Target Neighborhood Hits	407	Shared Neighborhood Hits	13
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

KRA13_HUMAN
θ value	0.279714 (rank : 138)	NC score	0.048830 (rank : 178)
Query Neighborhood Hits	251	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

NOTC1_HUMAN
θ value	0.365318 (rank : 139)	NC score	0.048975 (rank : 177)
Query Neighborhood Hits	251	Target Neighborhood Hits	906	Shared Neighborhood Hits	96
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

WISP2_MOUSE
θ value	0.365318 (rank : 140)	NC score	0.166626 (rank : 120)
Query Neighborhood Hits	251	Target Neighborhood Hits	129	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

CTGF_HUMAN
θ value	0.47712 (rank : 141)	NC score	0.106149 (rank : 130)
Query Neighborhood Hits	251	Target Neighborhood Hits	128	Shared Neighborhood Hits	53
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CYR61_MOUSE
θ value	0.47712 (rank : 142)	NC score	0.120220 (rank : 127)
Query Neighborhood Hits	251	Target Neighborhood Hits	156	Shared Neighborhood Hits	63
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

KR102_HUMAN
θ value	0.47712 (rank : 143)	NC score	0.088207 (rank : 135)
Query Neighborhood Hits	251	Target Neighborhood Hits	264	Shared Neighborhood Hits	59
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

RGS3_MOUSE
θ value	0.47712 (rank : 144)	NC score	0.008230 (rank : 234)
Query Neighborhood Hits	251	Target Neighborhood Hits	1621	Shared Neighborhood Hits	47
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

RSPO4_HUMAN
θ value	0.47712 (rank : 145)	NC score	0.075465 (rank : 143)
Query Neighborhood Hits	251	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

CREB5_HUMAN
θ value	0.62314 (rank : 146)	NC score	0.009919 (rank : 224)
Query Neighborhood Hits	251	Target Neighborhood Hits	222	Shared Neighborhood Hits	2
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

KRA11_HUMAN
θ value	0.62314 (rank : 147)	NC score	0.045008 (rank : 180)
Query Neighborhood Hits	251	Target Neighborhood Hits	155	Shared Neighborhood Hits	37
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

WISP3_HUMAN
θ value	0.62314 (rank : 148)	NC score	0.129938 (rank : 126)
Query Neighborhood Hits	251	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

CM031_MOUSE
θ value	0.813845 (rank : 149)	NC score	0.022242 (rank : 192)
Query Neighborhood Hits	251	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZT9, Q3U600	Gene names
Domain Architecture
Description	UPF0124 protein C13orf31 homolog.

CT012_MOUSE
θ value	0.813845 (rank : 150)	NC score	0.012360 (rank : 211)
Query Neighborhood Hits	251	Target Neighborhood Hits	229	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

MEFV_HUMAN
θ value	0.813845 (rank : 151)	NC score	0.001474 (rank : 267)
Query Neighborhood Hits	251	Target Neighborhood Hits	431	Shared Neighborhood Hits	11
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MMP26_HUMAN
θ value	0.813845 (rank : 152)	NC score	0.039390 (rank : 182)
Query Neighborhood Hits	251	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

NCOA2_HUMAN
θ value	0.813845 (rank : 153)	NC score	0.005823 (rank : 249)
Query Neighborhood Hits	251	Target Neighborhood Hits	281	Shared Neighborhood Hits	11
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PLMN_HUMAN
θ value	0.813845 (rank : 154)	NC score	0.001614 (rank : 265)
Query Neighborhood Hits	251	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

APBB1_MOUSE
θ value	1.06291 (rank : 155)	NC score	0.010450 (rank : 218)
Query Neighborhood Hits	251	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

KR106_HUMAN
θ value	1.06291 (rank : 156)	NC score	0.102169 (rank : 131)
Query Neighborhood Hits	251	Target Neighborhood Hits	347	Shared Neighborhood Hits	75
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

MUC1_HUMAN
θ value	1.06291 (rank : 157)	NC score	0.007929 (rank : 237)
Query Neighborhood Hits	251	Target Neighborhood Hits	975	Shared Neighborhood Hits	31
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PCSK5_MOUSE
θ value	1.06291 (rank : 158)	NC score	0.049740 (rank : 176)
Query Neighborhood Hits	251	Target Neighborhood Hits	613	Shared Neighborhood Hits	79
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PER3_HUMAN
θ value	1.06291 (rank : 159)	NC score	0.010080 (rank : 223)
Query Neighborhood Hits	251	Target Neighborhood Hits	479	Shared Neighborhood Hits	23
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PLMN_MOUSE
θ value	1.06291 (rank : 160)	NC score	0.000820 (rank : 270)
Query Neighborhood Hits	251	Target Neighborhood Hits	208	Shared Neighborhood Hits	5
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

SKIL_MOUSE
θ value	1.06291 (rank : 161)	NC score	0.000878 (rank : 269)
Query Neighborhood Hits	251	Target Neighborhood Hits	719	Shared Neighborhood Hits	5
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

TCF7_MOUSE
θ value	1.06291 (rank : 162)	NC score	0.006551 (rank : 244)
Query Neighborhood Hits	251	Target Neighborhood Hits	277	Shared Neighborhood Hits	8
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

CA106_HUMAN
θ value	1.38821 (rank : 163)	NC score	0.012760 (rank : 209)
Query Neighborhood Hits	251	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

FANCJ_MOUSE
θ value	1.38821 (rank : 164)	NC score	0.008382 (rank : 233)
Query Neighborhood Hits	251	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

KR104_HUMAN
θ value	1.38821 (rank : 165)	NC score	0.097583 (rank : 134)
Query Neighborhood Hits	251	Target Neighborhood Hits	313	Shared Neighborhood Hits	64
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KRA93_HUMAN
θ value	1.38821 (rank : 166)	NC score	0.080109 (rank : 140)
Query Neighborhood Hits	251	Target Neighborhood Hits	203	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

ZCHC5_HUMAN
θ value	1.38821 (rank : 167)	NC score	0.019498 (rank : 196)
Query Neighborhood Hits	251	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

AFF2_HUMAN
θ value	1.81305 (rank : 168)	NC score	0.010437 (rank : 220)
Query Neighborhood Hits	251	Target Neighborhood Hits	218	Shared Neighborhood Hits	12
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

CCNT2_HUMAN
θ value	1.81305 (rank : 169)	NC score	0.007320 (rank : 241)
Query Neighborhood Hits	251	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

EVI2B_HUMAN
θ value	1.81305 (rank : 170)	NC score	0.012423 (rank : 210)
Query Neighborhood Hits	251	Target Neighborhood Hits	135	Shared Neighborhood Hits	10
SwissProt Accessions	P34910	Gene names	EVI2B, EVDB
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

KR105_HUMAN
θ value	1.81305 (rank : 171)	NC score	0.060423 (rank : 159)
Query Neighborhood Hits	251	Target Neighborhood Hits	271	Shared Neighborhood Hits	55
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KRA15_HUMAN
θ value	1.81305 (rank : 172)	NC score	0.054494 (rank : 165)
Query Neighborhood Hits	251	Target Neighborhood Hits	126	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

MUC2_HUMAN
θ value	1.81305 (rank : 173)	NC score	0.042242 (rank : 181)
Query Neighborhood Hits	251	Target Neighborhood Hits	906	Shared Neighborhood Hits	72
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC7_HUMAN
θ value	1.81305 (rank : 174)	NC score	0.017470 (rank : 199)
Query Neighborhood Hits	251	Target Neighborhood Hits	538	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PRG3_HUMAN
θ value	1.81305 (rank : 175)	NC score	0.007964 (rank : 236)
Query Neighborhood Hits	251	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

WISP2_HUMAN
θ value	1.81305 (rank : 176)	NC score	0.166250 (rank : 121)
Query Neighborhood Hits	251	Target Neighborhood Hits	126	Shared Neighborhood Hits	61
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

CEND1_MOUSE
θ value	2.36792 (rank : 177)	NC score	0.001497 (rank : 266)
Query Neighborhood Hits	251	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

KRA92_HUMAN
θ value	2.36792 (rank : 178)	NC score	0.080093 (rank : 141)
Query Neighborhood Hits	251	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA98_HUMAN
θ value	2.36792 (rank : 179)	NC score	0.085051 (rank : 137)
Query Neighborhood Hits	251	Target Neighborhood Hits	185	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

MAP1A_HUMAN
θ value	2.36792 (rank : 180)	NC score	0.004414 (rank : 254)
Query Neighborhood Hits	251	Target Neighborhood Hits	1626	Shared Neighborhood Hits	32
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PODXL_HUMAN
θ value	2.36792 (rank : 181)	NC score	0.020787 (rank : 193)
Query Neighborhood Hits	251	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

RT35_HUMAN
θ value	2.36792 (rank : 182)	NC score	0.010393 (rank : 221)
Query Neighborhood Hits	251	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).

RXRB_HUMAN
θ value	2.36792 (rank : 183)	NC score	0.003566 (rank : 256)
Query Neighborhood Hits	251	Target Neighborhood Hits	280	Shared Neighborhood Hits	13
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

TARA_HUMAN
θ value	2.36792 (rank : 184)	NC score	0.003348 (rank : 258)
Query Neighborhood Hits	251	Target Neighborhood Hits	1626	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TM16H_HUMAN
θ value	2.36792 (rank : 185)	NC score	0.009016 (rank : 229)
Query Neighborhood Hits	251	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

TTLL5_HUMAN
θ value	2.36792 (rank : 186)	NC score	0.005137 (rank : 250)
Query Neighborhood Hits	251	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

ELK4_HUMAN
θ value	3.0926 (rank : 187)	NC score	0.003071 (rank : 260)
Query Neighborhood Hits	251	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

IPO13_HUMAN
θ value	3.0926 (rank : 188)	NC score	0.010462 (rank : 217)
Query Neighborhood Hits	251	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	O94829, Q7LC04, Q96HS3, Q9H8N3, Q9UFR1	Gene names	IPO13, KIAA0724, RANBP13
Domain Architecture	No domain graphic available
Description	Importin-13 (Imp13) (Ran-binding protein 13) (RanBP13) (Karyopherin 13) (Kap13).

IPO13_MOUSE
θ value	3.0926 (rank : 189)	NC score	0.010447 (rank : 219)
Query Neighborhood Hits	251	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0C1, Q6ZQ60	Gene names	Ipo13, Kiaa0724
Domain Architecture	No domain graphic available
Description	Importin-13 (Imp13).

MMP10_MOUSE
θ value	3.0926 (rank : 190)	NC score	0.008435 (rank : 232)
Query Neighborhood Hits	251	Target Neighborhood Hits	57	Shared Neighborhood Hits	12
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

PKHA3_MOUSE
θ value	3.0926 (rank : 191)	NC score	0.006768 (rank : 243)
Query Neighborhood Hits	251	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

TAF9_MOUSE
θ value	3.0926 (rank : 192)	NC score	0.009011 (rank : 230)
Query Neighborhood Hits	251	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

TNR8_HUMAN
θ value	3.0926 (rank : 193)	NC score	0.016687 (rank : 202)
Query Neighborhood Hits	251	Target Neighborhood Hits	198	Shared Neighborhood Hits	23
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

APBB1_HUMAN
θ value	4.03905 (rank : 194)	NC score	0.008838 (rank : 231)
Query Neighborhood Hits	251	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

BRWD1_MOUSE
θ value	4.03905 (rank : 195)	NC score	-0.000255 (rank : 274)
Query Neighborhood Hits	251	Target Neighborhood Hits	478	Shared Neighborhood Hits	5
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

EPHAA_HUMAN
θ value	4.03905 (rank : 196)	NC score	-0.004515 (rank : 280)
Query Neighborhood Hits	251	Target Neighborhood Hits	960	Shared Neighborhood Hits	10
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

KRA42_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.038322 (rank : 183)
Query Neighborhood Hits	251	Target Neighborhood Hits	149	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

MMP7_MOUSE
θ value	4.03905 (rank : 198)	NC score	0.032707 (rank : 188)
Query Neighborhood Hits	251	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

MUCDL_HUMAN
θ value	4.03905 (rank : 199)	NC score	0.016110 (rank : 203)
Query Neighborhood Hits	251	Target Neighborhood Hits	777	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MY116_MOUSE
θ value	4.03905 (rank : 200)	NC score	0.010705 (rank : 215)
Query Neighborhood Hits	251	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	P17564	Gene names	Myd116
Domain Architecture	No domain graphic available
Description	Myeloid differentiation primary response protein MyD116.

PCNT_HUMAN
θ value	4.03905 (rank : 201)	NC score	-0.006725 (rank : 281)
Query Neighborhood Hits	251	Target Neighborhood Hits	1551	Shared Neighborhood Hits	15
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RSPO1_HUMAN
θ value	4.03905 (rank : 202)	NC score	0.087981 (rank : 136)
Query Neighborhood Hits	251	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

STAB1_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.033569 (rank : 187)
Query Neighborhood Hits	251	Target Neighborhood Hits	546	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TITIN_HUMAN
θ value	4.03905 (rank : 204)	NC score	0.009248 (rank : 228)
Query Neighborhood Hits	251	Target Neighborhood Hits	2923	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ALKB1_HUMAN
θ value	5.27518 (rank : 205)	NC score	0.010138 (rank : 222)
Query Neighborhood Hits	251	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q13686, Q8TAU1, Q9ULA7	Gene names	ALKBH1, ABH, ALKBH
Domain Architecture	No domain graphic available
Description	Alkylated DNA repair protein alkB homolog 1.

CCD37_HUMAN
θ value	5.27518 (rank : 206)	NC score	0.002736 (rank : 261)
Query Neighborhood Hits	251	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

CSPG3_HUMAN
θ value	5.27518 (rank : 207)	NC score	0.007350 (rank : 240)
Query Neighborhood Hits	251	Target Neighborhood Hits	676	Shared Neighborhood Hits	34
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CT012_HUMAN
θ value	5.27518 (rank : 208)	NC score	0.007913 (rank : 238)
Query Neighborhood Hits	251	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DAAM1_MOUSE
θ value	5.27518 (rank : 209)	NC score	0.000489 (rank : 271)
Query Neighborhood Hits	251	Target Neighborhood Hits	443	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

JIP3_HUMAN
θ value	5.27518 (rank : 210)	NC score	-0.000952 (rank : 276)
Query Neighborhood Hits	251	Target Neighborhood Hits	1039	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

KRA94_HUMAN
θ value	5.27518 (rank : 211)	NC score	0.053903 (rank : 168)
Query Neighborhood Hits	251	Target Neighborhood Hits	204	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

MEP1B_MOUSE
θ value	5.27518 (rank : 212)	NC score	0.007354 (rank : 239)
Query Neighborhood Hits	251	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

RERE_MOUSE
θ value	5.27518 (rank : 213)	NC score	0.012095 (rank : 212)
Query Neighborhood Hits	251	Target Neighborhood Hits	785	Shared Neighborhood Hits	23
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

SOX30_HUMAN
θ value	5.27518 (rank : 214)	NC score	0.002670 (rank : 262)
Query Neighborhood Hits	251	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

TJAP1_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.011632 (rank : 213)
Query Neighborhood Hits	251	Target Neighborhood Hits	214	Shared Neighborhood Hits	8
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

WFDC3_HUMAN
θ value	5.27518 (rank : 216)	NC score	0.019685 (rank : 195)
Query Neighborhood Hits	251	Target Neighborhood Hits	138	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ANR11_HUMAN
θ value	6.88961 (rank : 217)	NC score	-0.003302 (rank : 278)
Query Neighborhood Hits	251	Target Neighborhood Hits	1289	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CN037_HUMAN
θ value	6.88961 (rank : 218)	NC score	0.007145 (rank : 242)
Query Neighborhood Hits	251	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

FINC_MOUSE
θ value	6.88961 (rank : 219)	NC score	0.000265 (rank : 273)
Query Neighborhood Hits	251	Target Neighborhood Hits	309	Shared Neighborhood Hits	14
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

ITB6_HUMAN
θ value	6.88961 (rank : 220)	NC score	0.023622 (rank : 191)
Query Neighborhood Hits	251	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

KR10A_HUMAN
θ value	6.88961 (rank : 221)	NC score	0.035589 (rank : 186)
Query Neighborhood Hits	251	Target Neighborhood Hits	232	Shared Neighborhood Hits	45
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KRA99_HUMAN
θ value	6.88961 (rank : 222)	NC score	0.053049 (rank : 169)
Query Neighborhood Hits	251	Target Neighborhood Hits	173	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LGR5_MOUSE
θ value	6.88961 (rank : 223)	NC score	-0.004211 (rank : 279)
Query Neighborhood Hits	251	Target Neighborhood Hits	484	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1P4	Gene names	Lgr5, Fex, Gpr49
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (G-protein coupled receptor 49) (Orphan G-protein coupled receptor FEX).

MEP1B_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.004779 (rank : 252)
Query Neighborhood Hits	251	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

RAI1_MOUSE
θ value	6.88961 (rank : 225)	NC score	0.009294 (rank : 227)
Query Neighborhood Hits	251	Target Neighborhood Hits	344	Shared Neighborhood Hits	17
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SRRM2_MOUSE
θ value	6.88961 (rank : 226)	NC score	0.005996 (rank : 245)
Query Neighborhood Hits	251	Target Neighborhood Hits	1470	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCOF_MOUSE
θ value	6.88961 (rank : 227)	NC score	0.010666 (rank : 216)
Query Neighborhood Hits	251	Target Neighborhood Hits	471	Shared Neighborhood Hits	19
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TCPH_HUMAN
θ value	6.88961 (rank : 228)	NC score	0.001082 (rank : 268)
Query Neighborhood Hits	251	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

ZCH14_HUMAN
θ value	6.88961 (rank : 229)	NC score	0.009389 (rank : 226)
Query Neighborhood Hits	251	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

ZN131_HUMAN
θ value	6.88961 (rank : 230)	NC score	-0.009022 (rank : 282)
Query Neighborhood Hits	251	Target Neighborhood Hits	833	Shared Neighborhood Hits	2
SwissProt Accessions	P52739, Q6PIF0	Gene names	ZNF131
Domain Architecture	No domain graphic available
Description	Zinc finger protein 131.

AFF2_MOUSE
θ value	8.99809 (rank : 231)	NC score	0.008182 (rank : 235)
Query Neighborhood Hits	251	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

BAP1_HUMAN
θ value	8.99809 (rank : 232)	NC score	0.003461 (rank : 257)
Query Neighborhood Hits	251	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

COHA1_HUMAN
θ value	8.99809 (rank : 233)	NC score	0.005850 (rank : 247)
Query Neighborhood Hits	251	Target Neighborhood Hits	400	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

DNM3A_HUMAN
θ value	8.99809 (rank : 234)	NC score	0.002330 (rank : 264)
Query Neighborhood Hits	251	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

DSCL1_HUMAN
θ value	8.99809 (rank : 235)	NC score	0.013287 (rank : 206)
Query Neighborhood Hits	251	Target Neighborhood Hits	589	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

HGFL_HUMAN
θ value	8.99809 (rank : 236)	NC score	-0.000665 (rank : 275)
Query Neighborhood Hits	251	Target Neighborhood Hits	190	Shared Neighborhood Hits	5
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

K0999_MOUSE
θ value	8.99809 (rank : 237)	NC score	-0.009145 (rank : 283)
Query Neighborhood Hits	251	Target Neighborhood Hits	931	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

LRP1B_MOUSE
θ value	8.99809 (rank : 238)	NC score	0.046667 (rank : 179)
Query Neighborhood Hits	251	Target Neighborhood Hits	606	Shared Neighborhood Hits	87
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MADCA_MOUSE
θ value	8.99809 (rank : 239)	NC score	0.010960 (rank : 214)
Query Neighborhood Hits	251	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	Q61826, O35530, Q61278, Q64275, Q8R1M6	Gene names	Madcam1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (mMAdCAM-1).

MAML1_HUMAN
θ value	8.99809 (rank : 240)	NC score	0.004588 (rank : 253)
Query Neighborhood Hits	251	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MBB1A_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.000283 (rank : 272)
Query Neighborhood Hits	251	Target Neighborhood Hits	665	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MMP11_HUMAN
θ value	8.99809 (rank : 242)	NC score	0.009660 (rank : 225)
Query Neighborhood Hits	251	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

MMP1B_MOUSE
θ value	8.99809 (rank : 243)	NC score	0.013143 (rank : 207)
Query Neighborhood Hits	251	Target Neighborhood Hits	64	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

MUC1_MOUSE
θ value	8.99809 (rank : 244)	NC score	0.018729 (rank : 197)
Query Neighborhood Hits	251	Target Neighborhood Hits	388	Shared Neighborhood Hits	21
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PF21B_MOUSE
θ value	8.99809 (rank : 245)	NC score	0.005013 (rank : 251)
Query Neighborhood Hits	251	Target Neighborhood Hits	278	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

SH2D5_MOUSE
θ value	8.99809 (rank : 246)	NC score	0.005837 (rank : 248)
Query Neighborhood Hits	251	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZW5	Gene names	Sh2d5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

SMG1_HUMAN
θ value	8.99809 (rank : 247)	NC score	0.002574 (rank : 263)
Query Neighborhood Hits	251	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

SMG1_MOUSE
θ value	8.99809 (rank : 248)	NC score	0.003119 (rank : 259)
Query Neighborhood Hits	251	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SPA3K_MOUSE
θ value	8.99809 (rank : 249)	NC score	-0.001925 (rank : 277)
Query Neighborhood Hits	251	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	P07759, Q91W80, Q91X80	Gene names	Serpina3k, Mcm2, Spi2
Domain Architecture
Description	Serine protease inhibitor A3K precursor (Contrapsin) (Serpin A3K).

TF3C1_HUMAN
θ value	8.99809 (rank : 250)	NC score	0.005959 (rank : 246)
Query Neighborhood Hits	251	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

ZAN_HUMAN
θ value	8.99809 (rank : 251)	NC score	0.037454 (rank : 184)
Query Neighborhood Hits	251	Target Neighborhood Hits	679	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ADA10_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.376917 (rank : 113)
Query Neighborhood Hits	251	Target Neighborhood Hits	189	Shared Neighborhood Hits	79
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.378211 (rank : 112)
Query Neighborhood Hits	251	Target Neighborhood Hits	194	Shared Neighborhood Hits	83
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

CO9_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.060333 (rank : 160)
Query Neighborhood Hits	251	Target Neighborhood Hits	147	Shared Neighborhood Hits	18
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.067523 (rank : 149)
Query Neighborhood Hits	251	Target Neighborhood Hits	153	Shared Neighborhood Hits	23
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.054005 (rank : 167)
Query Neighborhood Hits	251	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.052110 (rank : 171)
Query Neighborhood Hits	251	Target Neighborhood Hits	290	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

FRAS1_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.084337 (rank : 138)
Query Neighborhood Hits	251	Target Neighborhood Hits	759	Shared Neighborhood Hits	107
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KR101_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.068877 (rank : 148)
Query Neighborhood Hits	251	Target Neighborhood Hits	261	Shared Neighborhood Hits	54
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR107_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.080897 (rank : 139)
Query Neighborhood Hits	251	Target Neighborhood Hits	330	Shared Neighborhood Hits	64
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR109_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.060263 (rank : 161)
Query Neighborhood Hits	251	Target Neighborhood Hits	226	Shared Neighborhood Hits	45
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.063433 (rank : 155)
Query Neighborhood Hits	251	Target Neighborhood Hits	269	Shared Neighborhood Hits	55
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.061004 (rank : 158)
Query Neighborhood Hits	251	Target Neighborhood Hits	219	Shared Neighborhood Hits	46
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR412_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.054430 (rank : 166)
Query Neighborhood Hits	251	Target Neighborhood Hits	178	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA51_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.071712 (rank : 146)
Query Neighborhood Hits	251	Target Neighborhood Hits	288	Shared Neighborhood Hits	67
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.054995 (rank : 164)
Query Neighborhood Hits	251	Target Neighborhood Hits	236	Shared Neighborhood Hits	45
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.067436 (rank : 150)
Query Neighborhood Hits	251	Target Neighborhood Hits	331	Shared Neighborhood Hits	63
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.064649 (rank : 152)
Query Neighborhood Hits	251	Target Neighborhood Hits	270	Shared Neighborhood Hits	57
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA57_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.062749 (rank : 156)
Query Neighborhood Hits	251	Target Neighborhood Hits	269	Shared Neighborhood Hits	54
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.069948 (rank : 147)
Query Neighborhood Hits	251	Target Neighborhood Hits	324	Shared Neighborhood Hits	63
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LRP1B_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.050674 (rank : 175)
Query Neighborhood Hits	251	Target Neighborhood Hits	602	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MEGF6_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.050869 (rank : 174)
Query Neighborhood Hits	251	Target Neighborhood Hits	671	Shared Neighborhood Hits	106
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NFX1_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.059165 (rank : 162)
Query Neighborhood Hits	251	Target Neighborhood Hits	405	Shared Neighborhood Hits	52
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

RSPO1_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.074477 (rank : 144)
Query Neighborhood Hits	251	Target Neighborhood Hits	85	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO2_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.051645 (rank : 172)
Query Neighborhood Hits	251	Target Neighborhood Hits	90	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO3_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.061657 (rank : 157)
Query Neighborhood Hits	251	Target Neighborhood Hits	128	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.056192 (rank : 163)
Query Neighborhood Hits	251	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

SPON2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.075672 (rank : 142)
Query Neighborhood Hits	251	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON2_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.063922 (rank : 154)
Query Neighborhood Hits	251	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

TENX_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.063947 (rank : 153)
Query Neighborhood Hits	251	Target Neighborhood Hits	789	Shared Neighborhood Hits	100
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TSP3_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.052627 (rank : 170)
Query Neighborhood Hits	251	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.051397 (rank : 173)
Query Neighborhood Hits	251	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.072448 (rank : 145)
Query Neighborhood Hits	251	Target Neighborhood Hits	808	Shared Neighborhood Hits	116
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

ATS12_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	251	Target Neighborhood Hits	251	Shared Neighborhood Hits	251
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_MOUSE
NC score	0.994926 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	251	Target Neighborhood Hits	220	Shared Neighborhood Hits	158
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS7_HUMAN
NC score	0.984404 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	251	Target Neighborhood Hits	169	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS18_HUMAN
NC score	0.979052 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	251	Target Neighborhood Hits	169	Shared Neighborhood Hits	136
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
NC score	0.978484 (rank : 5)	θ value	3.82926e-184 (rank : 5)
Query Neighborhood Hits	251	Target Neighborhood Hits	163	Shared Neighborhood Hits	137
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_MOUSE
NC score	0.977625 (rank : 6)	θ value	2.57449e-172 (rank : 7)
Query Neighborhood Hits	251	Target Neighborhood Hits	179	Shared Neighborhood Hits	139
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_HUMAN
NC score	0.976829 (rank : 7)	θ value	1.50931e-172 (rank : 6)
Query Neighborhood Hits	251	Target Neighborhood Hits	208	Shared Neighborhood Hits	142
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS6_HUMAN
NC score	0.975731 (rank : 8)	θ value	5.3931e-154 (rank : 9)
Query Neighborhood Hits	251	Target Neighborhood Hits	141	Shared Neighborhood Hits	124
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS17_HUMAN
NC score	0.974003 (rank : 9)	θ value	1.33145e-144 (rank : 14)
Query Neighborhood Hits	251	Target Neighborhood Hits	194	Shared Neighborhood Hits	136
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS3_HUMAN
NC score	0.969545 (rank : 10)	θ value	4.29305e-135 (rank : 15)
Query Neighborhood Hits	251	Target Neighborhood Hits	179	Shared Neighborhood Hits	135
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS19_MOUSE
NC score	0.969494 (rank : 11)	θ value	9.19922e-154 (rank : 10)
Query Neighborhood Hits	251	Target Neighborhood Hits	188	Shared Neighborhood Hits	130
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS20_HUMAN
NC score	0.968633 (rank : 12)	θ value	7.28896e-151 (rank : 11)
Query Neighborhood Hits	251	Target Neighborhood Hits	192	Shared Neighborhood Hits	135
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS19_HUMAN
NC score	0.968380 (rank : 13)	θ value	6.80647e-157 (rank : 8)
Query Neighborhood Hits	251	Target Neighborhood Hits	203	Shared Neighborhood Hits	130
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS20_MOUSE
NC score	0.967907 (rank : 14)	θ value	1.24331e-150 (rank : 12)
Query Neighborhood Hits	251	Target Neighborhood Hits	225	Shared Neighborhood Hits	138
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS15_HUMAN
NC score	0.967469 (rank : 15)	θ value	8.69046e-120 (rank : 20)
Query Neighborhood Hits	251	Target Neighborhood Hits	151	Shared Neighborhood Hits	128
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS9_HUMAN
NC score	0.966812 (rank : 16)	θ value	2.34478e-149 (rank : 13)
Query Neighborhood Hits	251	Target Neighborhood Hits	219	Shared Neighborhood Hits	141
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS1_MOUSE
NC score	0.966211 (rank : 17)	θ value	4.74654e-134 (rank : 16)
Query Neighborhood Hits	251	Target Neighborhood Hits	158	Shared Neighborhood Hits	133
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS2_HUMAN
NC score	0.964939 (rank : 18)	θ value	7.86017e-121 (rank : 18)
Query Neighborhood Hits	251	Target Neighborhood Hits	179	Shared Neighborhood Hits	129
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
NC score	0.964744 (rank : 19)	θ value	1.34075e-120 (rank : 19)
Query Neighborhood Hits	251	Target Neighborhood Hits	179	Shared Neighborhood Hits	129
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS1_HUMAN
NC score	0.964575 (rank : 20)	θ value	9.92011e-124 (rank : 17)
Query Neighborhood Hits	251	Target Neighborhood Hits	159	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS5_MOUSE
NC score	0.962080 (rank : 21)	θ value	3.31772e-103 (rank : 23)
Query Neighborhood Hits	251	Target Neighborhood Hits	147	Shared Neighborhood Hits	123
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS8_HUMAN
NC score	0.961151 (rank : 22)	θ value	8.71062e-112 (rank : 22)
Query Neighborhood Hits	251	Target Neighborhood Hits	145	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS5_HUMAN
NC score	0.959735 (rank : 23)	θ value	1.3939e-101 (rank : 25)
Query Neighborhood Hits	251	Target Neighborhood Hits	141	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS14_HUMAN
NC score	0.959357 (rank : 24)	θ value	4.03687e-117 (rank : 21)
Query Neighborhood Hits	251	Target Neighborhood Hits	382	Shared Neighborhood Hits	135
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS8_MOUSE
NC score	0.953434 (rank : 25)	θ value	6.91785e-101 (rank : 26)
Query Neighborhood Hits	251	Target Neighborhood Hits	139	Shared Neighborhood Hits	115
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

ATS4_MOUSE
NC score	0.947124 (rank : 26)	θ value	9.98939e-100 (rank : 28)
Query Neighborhood Hits	251	Target Neighborhood Hits	145	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS4_HUMAN
NC score	0.945624 (rank : 27)	θ value	1.44246e-98 (rank : 29)
Query Neighborhood Hits	251	Target Neighborhood Hits	138	Shared Neighborhood Hits	113
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS13_HUMAN
NC score	0.933467 (rank : 28)	θ value	2.15048e-102 (rank : 24)
Query Neighborhood Hits	251	Target Neighborhood Hits	238	Shared Neighborhood Hits	116
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
NC score	0.932223 (rank : 29)	θ value	5.85632e-100 (rank : 27)
Query Neighborhood Hits	251	Target Neighborhood Hits	227	Shared Neighborhood Hits	123
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATL5_HUMAN
NC score	0.892735 (rank : 30)	θ value	1.46607e-42 (rank : 35)
Query Neighborhood Hits	251	Target Neighborhood Hits	103	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATL1_HUMAN
NC score	0.889345 (rank : 31)	θ value	5.19021e-56 (rank : 31)
Query Neighborhood Hits	251	Target Neighborhood Hits	93	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
NC score	0.882483 (rank : 32)	θ value	7.77379e-44 (rank : 34)
Query Neighborhood Hits	251	Target Neighborhood Hits	80	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL2_MOUSE
NC score	0.859896 (rank : 33)	θ value	1.15895e-47 (rank : 33)
Query Neighborhood Hits	251	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL2_HUMAN
NC score	0.859303 (rank : 34)	θ value	3.04986e-48 (rank : 32)
Query Neighborhood Hits	251	Target Neighborhood Hits	125	Shared Neighborhood Hits	86
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL3_HUMAN
NC score	0.751390 (rank : 35)	θ value	4.53632e-60 (rank : 30)
Query Neighborhood Hits	251	Target Neighborhood Hits	414	Shared Neighborhood Hits	101
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

PROP_HUMAN
NC score	0.629001 (rank : 36)	θ value	6.64225e-11 (rank : 78)
Query Neighborhood Hits	251	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
NC score	0.622381 (rank : 37)	θ value	1.33837e-11 (rank : 75)
Query Neighborhood Hits	251	Target Neighborhood Hits	165	Shared Neighborhood Hits	86
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

ADAM8_MOUSE
NC score	0.599358 (rank : 38)	θ value	7.56453e-23 (rank : 39)
Query Neighborhood Hits	251	Target Neighborhood Hits	326	Shared Neighborhood Hits	108
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM8_HUMAN
NC score	0.598467 (rank : 39)	θ value	3.51386e-20 (rank : 42)
Query Neighborhood Hits	251	Target Neighborhood Hits	327	Shared Neighborhood Hits	99
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADA28_MOUSE
NC score	0.598347 (rank : 40)	θ value	1.24688e-25 (rank : 38)
Query Neighborhood Hits	251	Target Neighborhood Hits	241	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA19_MOUSE
NC score	0.594104 (rank : 41)	θ value	1.24977e-17 (rank : 47)
Query Neighborhood Hits	251	Target Neighborhood Hits	315	Shared Neighborhood Hits	90
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA28_HUMAN
NC score	0.588293 (rank : 42)	θ value	1.47289e-26 (rank : 37)
Query Neighborhood Hits	251	Target Neighborhood Hits	244	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA19_HUMAN
NC score	0.587829 (rank : 43)	θ value	1.09232e-21 (rank : 40)
Query Neighborhood Hits	251	Target Neighborhood Hits	381	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

SPON1_HUMAN
NC score	0.580450 (rank : 44)	θ value	3.89403e-11 (rank : 77)
Query Neighborhood Hits	251	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

ADEC1_HUMAN
NC score	0.578237 (rank : 45)	θ value	1.9326e-10 (rank : 82)
Query Neighborhood Hits	251	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADA12_HUMAN
NC score	0.578158 (rank : 46)	θ value	2.69047e-20 (rank : 41)
Query Neighborhood Hits	251	Target Neighborhood Hits	224	Shared Neighborhood Hits	80
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

SPON1_MOUSE
NC score	0.578090 (rank : 47)	θ value	1.47974e-10 (rank : 81)
Query Neighborhood Hits	251	Target Neighborhood Hits	123	Shared Neighborhood Hits	94
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

CI094_HUMAN
NC score	0.577568 (rank : 48)	θ value	8.91499e-32 (rank : 36)
Query Neighborhood Hits	251	Target Neighborhood Hits	310	Shared Neighborhood Hits	77
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ADA33_HUMAN
NC score	0.576022 (rank : 49)	θ value	1.80466e-16 (rank : 50)
Query Neighborhood Hits	251	Target Neighborhood Hits	264	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA12_MOUSE
NC score	0.569756 (rank : 50)	θ value	1.33526e-19 (rank : 44)
Query Neighborhood Hits	251	Target Neighborhood Hits	474	Shared Neighborhood Hits	89
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADAM7_HUMAN
NC score	0.564571 (rank : 51)	θ value	7.32683e-18 (rank : 46)
Query Neighborhood Hits	251	Target Neighborhood Hits	221	Shared Neighborhood Hits	81
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
NC score	0.563071 (rank : 52)	θ value	1.92812e-18 (rank : 45)
Query Neighborhood Hits	251	Target Neighborhood Hits	200	Shared Neighborhood Hits	80
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM9_MOUSE
NC score	0.559364 (rank : 53)	θ value	7.82807e-20 (rank : 43)
Query Neighborhood Hits	251	Target Neighborhood Hits	325	Shared Neighborhood Hits	93
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADA15_HUMAN
NC score	0.554926 (rank : 54)	θ value	9.26847e-13 (rank : 67)
Query Neighborhood Hits	251	Target Neighborhood Hits	288	Shared Neighborhood Hits	95
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA33_MOUSE
NC score	0.549481 (rank : 55)	θ value	1.02475e-11 (rank : 74)
Query Neighborhood Hits	251	Target Neighborhood Hits	231	Shared Neighborhood Hits	86
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM9_HUMAN
NC score	0.549093 (rank : 56)	θ value	1.16975e-15 (rank : 54)
Query Neighborhood Hits	251	Target Neighborhood Hits	243	Shared Neighborhood Hits	85
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADA15_MOUSE
NC score	0.528134 (rank : 57)	θ value	3.18553e-13 (rank : 64)
Query Neighborhood Hits	251	Target Neighborhood Hits	324	Shared Neighborhood Hits	93
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADEC1_MOUSE
NC score	0.528086 (rank : 58)	θ value	0.000121331 (rank : 109)
Query Neighborhood Hits	251	Target Neighborhood Hits	85	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADM1B_MOUSE
NC score	0.527061 (rank : 59)	θ value	9.90251e-15 (rank : 56)
Query Neighborhood Hits	251	Target Neighborhood Hits	236	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADM1A_MOUSE
NC score	0.520216 (rank : 60)	θ value	8.95645e-16 (rank : 52)
Query Neighborhood Hits	251	Target Neighborhood Hits	230	Shared Neighborhood Hits	91
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA21_MOUSE
NC score	0.519020 (rank : 61)	θ value	5.43371e-13 (rank : 66)
Query Neighborhood Hits	251	Target Neighborhood Hits	172	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
NC score	0.518419 (rank : 62)	θ value	1.42992e-13 (rank : 62)
Query Neighborhood Hits	251	Target Neighborhood Hits	211	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA24_MOUSE
NC score	0.512923 (rank : 63)	θ value	2.28291e-11 (rank : 76)
Query Neighborhood Hits	251	Target Neighborhood Hits	230	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

THSD1_HUMAN
NC score	0.510446 (rank : 64)	θ value	1.29631e-06 (rank : 102)
Query Neighborhood Hits	251	Target Neighborhood Hits	136	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

ADA23_MOUSE
NC score	0.509996 (rank : 65)	θ value	1.09485e-13 (rank : 61)
Query Neighborhood Hits	251	Target Neighborhood Hits	245	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA22_MOUSE
NC score	0.508452 (rank : 66)	θ value	8.67504e-11 (rank : 79)
Query Neighborhood Hits	251	Target Neighborhood Hits	225	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA29_HUMAN
NC score	0.507563 (rank : 67)	θ value	1.133e-10 (rank : 80)
Query Neighborhood Hits	251	Target Neighborhood Hits	247	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA25_MOUSE
NC score	0.505599 (rank : 68)	θ value	2.79066e-09 (rank : 86)
Query Neighborhood Hits	251	Target Neighborhood Hits	213	Shared Neighborhood Hits	85
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA21_HUMAN
NC score	0.505153 (rank : 69)	θ value	1.58096e-12 (rank : 69)
Query Neighborhood Hits	251	Target Neighborhood Hits	181	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

AD26A_MOUSE
NC score	0.504648 (rank : 70)	θ value	1.52774e-15 (rank : 55)
Query Neighborhood Hits	251	Target Neighborhood Hits	165	Shared Neighborhood Hits	82
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA23_HUMAN
NC score	0.501584 (rank : 71)	θ value	4.59992e-12 (rank : 73)
Query Neighborhood Hits	251	Target Neighborhood Hits	235	Shared Neighborhood Hits	79
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA11_MOUSE
NC score	0.489111 (rank : 72)	θ value	2.13673e-09 (rank : 85)
Query Neighborhood Hits	251	Target Neighborhood Hits	263	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

THSD1_MOUSE
NC score	0.477366 (rank : 73)	θ value	5.44631e-05 (rank : 108)
Query Neighborhood Hits	251	Target Neighborhood Hits	153	Shared Neighborhood Hits	79
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TSP1_HUMAN
NC score	0.468413 (rank : 74)	θ value	1.38178e-16 (rank : 49)
Query Neighborhood Hits	251	Target Neighborhood Hits	389	Shared Neighborhood Hits	110
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
NC score	0.467505 (rank : 75)	θ value	4.02038e-16 (rank : 51)
Query Neighborhood Hits	251	Target Neighborhood Hits	396	Shared Neighborhood Hits	111
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

ADA11_HUMAN
NC score	0.464986 (rank : 76)	θ value	3.41135e-07 (rank : 99)
Query Neighborhood Hits	251	Target Neighborhood Hits	259	Shared Neighborhood Hits	77
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

TSP2_MOUSE
NC score	0.464612 (rank : 77)	θ value	3.76295e-14 (rank : 60)
Query Neighborhood Hits	251	Target Neighborhood Hits	352	Shared Neighborhood Hits	110
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADA20_HUMAN
NC score	0.464452 (rank : 78)	θ value	5.26297e-08 (rank : 91)
Query Neighborhood Hits	251	Target Neighborhood Hits	143	Shared Neighborhood Hits	79
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADAM2_MOUSE
NC score	0.464098 (rank : 79)	θ value	5.26297e-08 (rank : 92)
Query Neighborhood Hits	251	Target Neighborhood Hits	209	Shared Neighborhood Hits	83
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

TSP2_HUMAN
NC score	0.462768 (rank : 80)	θ value	9.90251e-15 (rank : 57)
Query Neighborhood Hits	251	Target Neighborhood Hits	359	Shared Neighborhood Hits	115
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

BAI2_HUMAN
NC score	0.459950 (rank : 81)	θ value	2.43908e-13 (rank : 63)
Query Neighborhood Hits	251	Target Neighborhood Hits	332	Shared Neighborhood Hits	94
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

UNC5A_MOUSE
NC score	0.459779 (rank : 82)	θ value	1.80886e-08 (rank : 88)
Query Neighborhood Hits	251	Target Neighborhood Hits	203	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

BAI1_MOUSE
NC score	0.457692 (rank : 83)	θ value	9.59137e-10 (rank : 84)
Query Neighborhood Hits	251	Target Neighborhood Hits	340	Shared Neighborhood Hits	99
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_MOUSE
NC score	0.457573 (rank : 84)	θ value	1.2105e-12 (rank : 68)
Query Neighborhood Hits	251	Target Neighborhood Hits	323	Shared Neighborhood Hits	97
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ADA32_HUMAN
NC score	0.456991 (rank : 85)	θ value	1.69304e-06 (rank : 103)
Query Neighborhood Hits	251	Target Neighborhood Hits	216	Shared Neighborhood Hits	77
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
NC score	0.456625 (rank : 86)	θ value	2.79066e-09 (rank : 87)
Query Neighborhood Hits	251	Target Neighborhood Hits	219	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

BAI3_HUMAN
NC score	0.456482 (rank : 87)	θ value	4.16044e-13 (rank : 65)
Query Neighborhood Hits	251	Target Neighborhood Hits	246	Shared Neighborhood Hits	90
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI1_HUMAN
NC score	0.455661 (rank : 88)	θ value	9.59137e-10 (rank : 83)
Query Neighborhood Hits	251	Target Neighborhood Hits	375	Shared Neighborhood Hits	96
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI3_MOUSE
NC score	0.455515 (rank : 89)	θ value	2.0648e-12 (rank : 72)
Query Neighborhood Hits	251	Target Neighborhood Hits	250	Shared Neighborhood Hits	92
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

UNC5B_MOUSE
NC score	0.449227 (rank : 90)	θ value	3.08544e-08 (rank : 90)
Query Neighborhood Hits	251	Target Neighborhood Hits	226	Shared Neighborhood Hits	79
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5B_HUMAN
NC score	0.446909 (rank : 91)	θ value	3.08544e-08 (rank : 89)
Query Neighborhood Hits	251	Target Neighborhood Hits	225	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

ADA18_MOUSE
NC score	0.440553 (rank : 92)	θ value	2.21117e-06 (rank : 104)
Query Neighborhood Hits	251	Target Neighborhood Hits	227	Shared Neighborhood Hits	91
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

UNC5C_MOUSE
NC score	0.433486 (rank : 93)	θ value	6.87365e-08 (rank : 94)
Query Neighborhood Hits	251	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.433120 (rank : 94)	θ value	6.87365e-08 (rank : 93)
Query Neighborhood Hits	251	Target Neighborhood Hits	226	Shared Neighborhood Hits	79
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

ADAM2_HUMAN
NC score	0.429610 (rank : 95)	θ value	1.99992e-07 (rank : 97)
Query Neighborhood Hits	251	Target Neighborhood Hits	175	Shared Neighborhood Hits	74
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

SEM5A_HUMAN
NC score	0.429577 (rank : 96)	θ value	2.20605e-14 (rank : 58)
Query Neighborhood Hits	251	Target Neighborhood Hits	177	Shared Neighborhood Hits	87
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SSPO_MOUSE
NC score	0.426404 (rank : 97)	θ value	8.95645e-16 (rank : 53)
Query Neighborhood Hits	251	Target Neighborhood Hits	800	Shared Neighborhood Hits	151
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

UNC5D_HUMAN
NC score	0.425514 (rank : 98)	θ value	3.41135e-07 (rank : 100)
Query Neighborhood Hits	251	Target Neighborhood Hits	267	Shared Neighborhood Hits	77
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
NC score	0.421937 (rank : 99)	θ value	3.41135e-07 (rank : 101)
Query Neighborhood Hits	251	Target Neighborhood Hits	268	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

SEM5A_MOUSE
NC score	0.420821 (rank : 100)	θ value	2.88119e-14 (rank : 59)
Query Neighborhood Hits	251	Target Neighborhood Hits	162	Shared Neighborhood Hits	88
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

CO8A_HUMAN
NC score	0.418519 (rank : 101)	θ value	1.87187e-05 (rank : 106)
Query Neighborhood Hits	251	Target Neighborhood Hits	200	Shared Neighborhood Hits	73
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ADA18_HUMAN
NC score	0.417793 (rank : 102)	θ value	8.97725e-08 (rank : 95)
Query Neighborhood Hits	251	Target Neighborhood Hits	184	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

SEM5B_MOUSE
NC score	0.416780 (rank : 103)	θ value	1.58096e-12 (rank : 71)
Query Neighborhood Hits	251	Target Neighborhood Hits	190	Shared Neighborhood Hits	88
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5B_HUMAN
NC score	0.414958 (rank : 104)	θ value	1.58096e-12 (rank : 70)
Query Neighborhood Hits	251	Target Neighborhood Hits	178	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

CO6_HUMAN
NC score	0.413630 (rank : 105)	θ value	1.17247e-07 (rank : 96)
Query Neighborhood Hits	251	Target Neighborhood Hits	331	Shared Neighborhood Hits	83
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO8A_MOUSE
NC score	0.413094 (rank : 106)	θ value	2.21117e-06 (rank : 105)
Query Neighborhood Hits	251	Target Neighborhood Hits	182	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ADA30_HUMAN
NC score	0.407295 (rank : 107)	θ value	2.44474e-05 (rank : 107)
Query Neighborhood Hits	251	Target Neighborhood Hits	391	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA17_MOUSE
NC score	0.393168 (rank : 108)	θ value	0.00228821 (rank : 112)
Query Neighborhood Hits	251	Target Neighborhood Hits	201	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

CO8B_MOUSE
NC score	0.393100 (rank : 109)	θ value	0.000121331 (rank : 110)
Query Neighborhood Hits	251	Target Neighborhood Hits	224	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CILP2_HUMAN
NC score	0.386538 (rank : 110)	θ value	0.00665767 (rank : 116)
Query Neighborhood Hits	251	Target Neighborhood Hits	307	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

ADA17_HUMAN
NC score	0.379060 (rank : 111)	θ value	0.0431538 (rank : 124)
Query Neighborhood Hits	251	Target Neighborhood Hits	223	Shared Neighborhood Hits	84
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA10_MOUSE
NC score	0.378211 (rank : 112)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	251	Target Neighborhood Hits	194	Shared Neighborhood Hits	83
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA10_HUMAN
NC score	0.376917 (rank : 113)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	251	Target Neighborhood Hits	189	Shared Neighborhood Hits	79
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

CO7_HUMAN
NC score	0.372540 (rank : 114)	θ value	1.99992e-07 (rank : 98)
Query Neighborhood Hits	251	Target Neighborhood Hits	278	Shared Neighborhood Hits	72
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

UNC5A_HUMAN
NC score	0.371121 (rank : 115)	θ value	0.00228821 (rank : 114)
Query Neighborhood Hits	251	Target Neighborhood Hits	198	Shared Neighborhood Hits	75
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

CO8B_HUMAN
NC score	0.357276 (rank : 116)	θ value	0.000461057 (rank : 111)
Query Neighborhood Hits	251	Target Neighborhood Hits	199	Shared Neighborhood Hits	67
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

HMCN1_HUMAN
NC score	0.285715 (rank : 117)	θ value	2.13179e-17 (rank : 48)
Query Neighborhood Hits	251	Target Neighborhood Hits	983	Shared Neighborhood Hits	120
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CILP1_MOUSE
NC score	0.283692 (rank : 118)	θ value	0.0193708 (rank : 121)
Query Neighborhood Hits	251	Target Neighborhood Hits	282	Shared Neighborhood Hits	78
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_HUMAN
NC score	0.283088 (rank : 119)	θ value	0.00869519 (rank : 118)
Query Neighborhood Hits	251	Target Neighborhood Hits	266	Shared Neighborhood Hits	78
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

WISP2_MOUSE
NC score	0.166626 (rank : 120)	θ value	0.365318 (rank : 140)
Query Neighborhood Hits	251	Target Neighborhood Hits	129	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

WISP2_HUMAN
NC score	0.166250 (rank : 121)	θ value	1.81305 (rank : 176)
Query Neighborhood Hits	251	Target Neighborhood Hits	126	Shared Neighborhood Hits	61
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP1_MOUSE
NC score	0.152479 (rank : 122)	θ value	0.125558 (rank : 131)
Query Neighborhood Hits	251	Target Neighborhood Hits	123	Shared Neighborhood Hits	61
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP1_HUMAN
NC score	0.145315 (rank : 123)	θ value	0.21417 (rank : 134)
Query Neighborhood Hits	251	Target Neighborhood Hits	121	Shared Neighborhood Hits	64
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

CYR61_HUMAN
NC score	0.136116 (rank : 124)	θ value	0.163984 (rank : 132)
Query Neighborhood Hits	251	Target Neighborhood Hits	159	Shared Neighborhood Hits	69
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

NOV_MOUSE
NC score	0.132524 (rank : 125)	θ value	0.0961366 (rank : 127)
Query Neighborhood Hits	251	Target Neighborhood Hits	130	Shared Neighborhood Hits	61
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

WISP3_HUMAN
NC score	0.129938 (rank : 126)	θ value	0.62314 (rank : 148)
Query Neighborhood Hits	251	Target Neighborhood Hits	87	Shared Neighborhood Hits	48
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

CYR61_MOUSE
NC score	0.120220 (rank : 127)	θ value	0.47712 (rank : 142)
Query Neighborhood Hits	251	Target Neighborhood Hits	156	Shared Neighborhood Hits	63
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

NOV_HUMAN
NC score	0.119538 (rank : 128)	θ value	0.0252991 (rank : 122)
Query Neighborhood Hits	251	Target Neighborhood Hits	128	Shared Neighborhood Hits	58
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

CTGF_MOUSE
NC score	0.112814 (rank : 129)	θ value	0.125558 (rank : 128)
Query Neighborhood Hits	251	Target Neighborhood Hits	124	Shared Neighborhood Hits	56
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CTGF_HUMAN
NC score	0.106149 (rank : 130)	θ value	0.47712 (rank : 141)
Query Neighborhood Hits	251	Target Neighborhood Hits	128	Shared Neighborhood Hits	53
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

KR106_HUMAN
NC score	0.102169 (rank : 131)	θ value	1.06291 (rank : 156)
Query Neighborhood Hits	251	Target Neighborhood Hits	347	Shared Neighborhood Hits	75
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

FRAS1_MOUSE
NC score	0.100082 (rank : 132)	θ value	0.163984 (rank : 133)
Query Neighborhood Hits	251	Target Neighborhood Hits	747	Shared Neighborhood Hits	109
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

RSPO4_MOUSE
NC score	0.099407 (rank : 133)	θ value	0.0252991 (rank : 123)
Query Neighborhood Hits	251	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

KR104_HUMAN
NC score	0.097583 (rank : 134)	θ value	1.38821 (rank : 165)
Query Neighborhood Hits	251	Target Neighborhood Hits	313	Shared Neighborhood Hits	64
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR102_HUMAN
NC score	0.088207 (rank : 135)	θ value	0.47712 (rank : 143)
Query Neighborhood Hits	251	Target Neighborhood Hits	264	Shared Neighborhood Hits	59
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

RSPO1_HUMAN
NC score	0.087981 (rank : 136)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	251	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

KRA98_HUMAN
NC score	0.085051 (rank : 137)	θ value	2.36792 (rank : 179)
Query Neighborhood Hits	251	Target Neighborhood Hits	185	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

FRAS1_HUMAN
NC score	0.084337 (rank : 138)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	251	Target Neighborhood Hits	759	Shared Neighborhood Hits	107
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KR107_HUMAN
NC score	0.080897 (rank : 139)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	251	Target Neighborhood Hits	330	Shared Neighborhood Hits	64
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA93_HUMAN
NC score	0.080109 (rank : 140)	θ value	1.38821 (rank : 166)
Query Neighborhood Hits	251	Target Neighborhood Hits	203	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA92_HUMAN
NC score	0.080093 (rank : 141)	θ value	2.36792 (rank : 178)
Query Neighborhood Hits	251	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

SPON2_HUMAN
NC score	0.075672 (rank : 142)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	251	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

RSPO4_HUMAN
NC score	0.075465 (rank : 143)	θ value	0.47712 (rank : 145)
Query Neighborhood Hits	251	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO1_MOUSE
NC score	0.074477 (rank : 144)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	251	Target Neighborhood Hits	85	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

ZAN_MOUSE
NC score	0.072448 (rank : 145)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	251	Target Neighborhood Hits	808	Shared Neighborhood Hits	116
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KRA51_HUMAN
NC score	0.071712 (rank : 146)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	251	Target Neighborhood Hits	288	Shared Neighborhood Hits	67
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA58_HUMAN
NC score	0.069948 (rank : 147)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	251	Target Neighborhood Hits	324	Shared Neighborhood Hits	63
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KR101_HUMAN
NC score	0.068877 (rank : 148)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	251	Target Neighborhood Hits	261	Shared Neighborhood Hits	54
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

CO9_MOUSE
NC score	0.067523 (rank : 149)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	251	Target Neighborhood Hits	153	Shared Neighborhood Hits	23
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

KRA53_HUMAN
NC score	0.067436 (rank : 150)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	251	Target Neighborhood Hits	331	Shared Neighborhood Hits	63
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

CRIM1_HUMAN
NC score	0.065920 (rank : 151)	θ value	0.0736092 (rank : 126)
Query Neighborhood Hits	251	Target Neighborhood Hits	362	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KRA54_HUMAN
NC score	0.064649 (rank : 152)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	251	Target Neighborhood Hits	270	Shared Neighborhood Hits	57
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

TENX_HUMAN
NC score	0.063947 (rank : 153)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	251	Target Neighborhood Hits	789	Shared Neighborhood Hits	100
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

SPON2_MOUSE
NC score	0.063922 (rank : 154)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	251	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

KR10B_HUMAN
NC score	0.063433 (rank : 155)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	251	Target Neighborhood Hits	269	Shared Neighborhood Hits	55
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KRA57_HUMAN
NC score	0.062749 (rank : 156)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	251	Target Neighborhood Hits	269	Shared Neighborhood Hits	54
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

RSPO3_HUMAN
NC score	0.061657 (rank : 157)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	251	Target Neighborhood Hits	128	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

KR10C_HUMAN
NC score	0.061004 (rank : 158)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	251	Target Neighborhood Hits	219	Shared Neighborhood Hits	46
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR105_HUMAN
NC score	0.060423 (rank : 159)	θ value	1.81305 (rank : 171)
Query Neighborhood Hits	251	Target Neighborhood Hits	271	Shared Neighborhood Hits	55
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

CO9_HUMAN
NC score	0.060333 (rank : 160)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	251	Target Neighborhood Hits	147	Shared Neighborhood Hits	18
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

KR109_HUMAN
NC score	0.060263 (rank : 161)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	251	Target Neighborhood Hits	226	Shared Neighborhood Hits	45
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

NFX1_HUMAN
NC score	0.059165 (rank : 162)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	251	Target Neighborhood Hits	405	Shared Neighborhood Hits	52
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

RSPO3_MOUSE
NC score	0.056192 (rank : 163)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	251	Target Neighborhood Hits	120	Shared Neighborhood Hits	32
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

KRA52_HUMAN
NC score	0.054995 (rank : 164)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	251	Target Neighborhood Hits	236	Shared Neighborhood Hits	45
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA15_HUMAN
NC score	0.054494 (rank : 165)	θ value	1.81305 (rank : 172)
Query Neighborhood Hits	251	Target Neighborhood Hits	126	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KR412_HUMAN
NC score	0.054430 (rank : 166)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	251	Target Neighborhood Hits	178	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

COMP_HUMAN
NC score	0.054005 (rank : 167)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	251	Target Neighborhood Hits	258	Shared Neighborhood Hits	20
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KRA94_HUMAN
NC score	0.053903 (rank : 168)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	251	Target Neighborhood Hits	204	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA99_HUMAN
NC score	0.053049 (rank : 169)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	251	Target Neighborhood Hits	173	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

TSP3_HUMAN
NC score	0.052627 (rank : 170)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	251	Target Neighborhood Hits	250	Shared Neighborhood Hits	14
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

COMP_MOUSE
NC score	0.052110 (rank : 171)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	251	Target Neighborhood Hits	290	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

RSPO2_HUMAN
NC score	0.051645 (rank : 172)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	251	Target Neighborhood Hits	90	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

TSP3_MOUSE
NC score	0.051397 (rank : 173)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	251	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

MEGF6_HUMAN
NC score	0.050869 (rank : 174)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	251	Target Neighborhood Hits	671	Shared Neighborhood Hits	106
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LRP1B_HUMAN
NC score	0.050674 (rank : 175)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	251	Target Neighborhood Hits	602	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

PCSK5_MOUSE
NC score	0.049740 (rank : 176)	θ value	1.06291 (rank : 158)
Query Neighborhood Hits	251	Target Neighborhood Hits	613	Shared Neighborhood Hits	79
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

NOTC1_HUMAN
NC score	0.048975 (rank : 177)	θ value	0.365318 (rank : 139)
Query Neighborhood Hits	251	Target Neighborhood Hits	906	Shared Neighborhood Hits	96
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KRA13_HUMAN
NC score	0.048830 (rank : 178)	θ value	0.279714 (rank : 138)
Query Neighborhood Hits	251	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

LRP1B_MOUSE
NC score	0.046667 (rank : 179)	θ value	8.99809 (rank : 238)
Query Neighborhood Hits	251	Target Neighborhood Hits	606	Shared Neighborhood Hits	87
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KRA11_HUMAN
NC score	0.045008 (rank : 180)	θ value	0.62314 (rank : 147)
Query Neighborhood Hits	251	Target Neighborhood Hits	155	Shared Neighborhood Hits	37
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

MUC2_HUMAN
NC score	0.042242 (rank : 181)	θ value	1.81305 (rank : 173)
Query Neighborhood Hits	251	Target Neighborhood Hits	906	Shared Neighborhood Hits	72
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MMP26_HUMAN
NC score	0.039390 (rank : 182)	θ value	0.813845 (rank : 152)
Query Neighborhood Hits	251	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRE1, Q9GZS2, Q9NR87	Gene names	MMP26
Domain Architecture
Description	Matrix metalloproteinase-26 precursor (EC 3.4.24.-) (MMP-26) (Matrilysin-2) (Endometase).

KRA42_HUMAN
NC score	0.038322 (rank : 183)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	251	Target Neighborhood Hits	149	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

ZAN_HUMAN
NC score	0.037454 (rank : 184)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	251	Target Neighborhood Hits	679	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

SPESP_MOUSE
NC score	0.036952 (rank : 185)	θ value	0.0113563 (rank : 119)
Query Neighborhood Hits	251	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D5A0, Q9D5X8	Gene names	Spesp1
Domain Architecture	No domain graphic available
Description	Sperm equatorial segment protein 1 precursor.

KR10A_HUMAN
NC score	0.035589 (rank : 186)	θ value	6.88961 (rank : 221)
Query Neighborhood Hits	251	Target Neighborhood Hits	232	Shared Neighborhood Hits	45
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

STAB1_HUMAN
NC score	0.033569 (rank : 187)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	251	Target Neighborhood Hits	546	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

MMP7_MOUSE
NC score	0.032707 (rank : 188)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	251	Target Neighborhood Hits	60	Shared Neighborhood Hits	24
SwissProt Accessions	Q10738	Gene names	Mmp7
Domain Architecture
Description	Matrilysin precursor (EC 3.4.24.23) (Pump-1 protease) (Uterine metalloproteinase) (Matrix metalloproteinase-7) (MMP-7) (Matrin).

GMEB2_HUMAN
NC score	0.025964 (rank : 189)	θ value	0.0563607 (rank : 125)
Query Neighborhood Hits	251	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

GMEB2_MOUSE
NC score	0.024838 (rank : 190)	θ value	0.125558 (rank : 129)
Query Neighborhood Hits	251	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

ITB6_HUMAN
NC score	0.023622 (rank : 191)	θ value	6.88961 (rank : 220)
Query Neighborhood Hits	251	Target Neighborhood Hits	318	Shared Neighborhood Hits	52
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

CM031_MOUSE
NC score	0.022242 (rank : 192)	θ value	0.813845 (rank : 149)
Query Neighborhood Hits	251	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZT9, Q3U600	Gene names
Domain Architecture
Description	UPF0124 protein C13orf31 homolog.

PODXL_HUMAN
NC score	0.020787 (rank : 193)	θ value	2.36792 (rank : 181)
Query Neighborhood Hits	251	Target Neighborhood Hits	191	Shared Neighborhood Hits	14
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

NACAM_MOUSE
NC score	0.020692 (rank : 194)	θ value	0.00665767 (rank : 117)
Query Neighborhood Hits	251	Target Neighborhood Hits	1866	Shared Neighborhood Hits	57
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

WFDC3_HUMAN
NC score	0.019685 (rank : 195)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	251	Target Neighborhood Hits	138	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ZCHC5_HUMAN
NC score	0.019498 (rank : 196)	θ value	1.38821 (rank : 167)
Query Neighborhood Hits	251	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8U3	Gene names	ZCCHC5
Domain Architecture
Description	Zinc finger CCHC domain-containing protein 5.

MUC1_MOUSE
NC score	0.018729 (rank : 197)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	251	Target Neighborhood Hits	388	Shared Neighborhood Hits	21
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

TJAP1_MOUSE
NC score	0.017516 (rank : 198)	θ value	0.125558 (rank : 130)
Query Neighborhood Hits	251	Target Neighborhood Hits	295	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

MUC7_HUMAN
NC score	0.017470 (rank : 199)	θ value	1.81305 (rank : 174)
Query Neighborhood Hits	251	Target Neighborhood Hits	538	Shared Neighborhood Hits	29
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MDC1_HUMAN
NC score	0.017191 (rank : 200)	θ value	0.00298849 (rank : 115)
Query Neighborhood Hits	251	Target Neighborhood Hits	1446	Shared Neighborhood Hits	40
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

SYNJ2_MOUSE
NC score	0.016727 (rank : 201)	θ value	0.0148317 (rank : 120)
Query Neighborhood Hits	251	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2G5, O35404, O88399, O88400, O88401, O88402, O88403, O88404	Gene names	Synj2, Kiaa0348
Domain Architecture
Description	Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 2).

TNR8_HUMAN
NC score	0.016687 (rank : 202)	θ value	3.0926 (rank : 193)
Query Neighborhood Hits	251	Target Neighborhood Hits	198	Shared Neighborhood Hits	23
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

MUCDL_HUMAN
NC score	0.016110 (rank : 203)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	251	Target Neighborhood Hits	777	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

EMIL3_MOUSE
NC score	0.015189 (rank : 204)	θ value	0.279714 (rank : 136)
Query Neighborhood Hits	251	Target Neighborhood Hits	240	Shared Neighborhood Hits	6
SwissProt Accessions	P59900	Gene names	Emilin3, Emilin5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5).

EMIL3_HUMAN
NC score	0.015060 (rank : 205)	θ value	0.279714 (rank : 135)
Query Neighborhood Hits	251	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

DSCL1_HUMAN
NC score	0.013287 (rank : 206)	θ value	8.99809 (rank : 235)
Query Neighborhood Hits	251	Target Neighborhood Hits	589	Shared Neighborhood Hits	26
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

MMP1B_MOUSE
NC score	0.013143 (rank : 207)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	251	Target Neighborhood Hits	64	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EPL6	Gene names	Mmp1b, McolB
Domain Architecture	No domain graphic available
Description	Interstitial collagenase B precursor (EC 3.4.24.7) (Matrix metalloproteinase-1b) (MMP-1b) (Mcol-B).

MAGE1_HUMAN
NC score	0.012962 (rank : 208)	θ value	0.00228821 (rank : 113)
Query Neighborhood Hits	251	Target Neighborhood Hits	1389	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CA106_HUMAN
NC score	0.012760 (rank : 209)	θ value	1.38821 (rank : 163)
Query Neighborhood Hits	251	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

EVI2B_HUMAN
NC score	0.012423 (rank : 210)	θ value	1.81305 (rank : 170)
Query Neighborhood Hits	251	Target Neighborhood Hits	135	Shared Neighborhood Hits	10
SwissProt Accessions	P34910	Gene names	EVI2B, EVDB
Domain Architecture	No domain graphic available
Description	EVI2B protein precursor (Ecotropic viral integration site 2B protein).

CT012_MOUSE
NC score	0.012360 (rank : 211)	θ value	0.813845 (rank : 150)
Query Neighborhood Hits	251	Target Neighborhood Hits	229	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

RERE_MOUSE
NC score	0.012095 (rank : 212)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	251	Target Neighborhood Hits	785	Shared Neighborhood Hits	23
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

TJAP1_HUMAN
NC score	0.011632 (rank : 213)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	251	Target Neighborhood Hits	214	Shared Neighborhood Hits	8
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

MADCA_MOUSE
NC score	0.010960 (rank : 214)	θ value	8.99809 (rank : 239)
Query Neighborhood Hits	251	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	Q61826, O35530, Q61278, Q64275, Q8R1M6	Gene names	Madcam1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (mMAdCAM-1).

MY116_MOUSE
NC score	0.010705 (rank : 215)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	251	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	P17564	Gene names	Myd116
Domain Architecture	No domain graphic available
Description	Myeloid differentiation primary response protein MyD116.

TCOF_MOUSE
NC score	0.010666 (rank : 216)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	251	Target Neighborhood Hits	471	Shared Neighborhood Hits	19
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

IPO13_HUMAN
NC score	0.010462 (rank : 217)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	251	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	O94829, Q7LC04, Q96HS3, Q9H8N3, Q9UFR1	Gene names	IPO13, KIAA0724, RANBP13
Domain Architecture	No domain graphic available
Description	Importin-13 (Imp13) (Ran-binding protein 13) (RanBP13) (Karyopherin 13) (Kap13).

APBB1_MOUSE
NC score	0.010450 (rank : 218)	θ value	1.06291 (rank : 155)
Query Neighborhood Hits	251	Target Neighborhood Hits	75	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QXJ1, O08642, Q3TPU0, Q8BNF4, Q8BSR9	Gene names	Apbb1, Fe65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

IPO13_MOUSE
NC score	0.010447 (rank : 219)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	251	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0C1, Q6ZQ60	Gene names	Ipo13, Kiaa0724
Domain Architecture	No domain graphic available
Description	Importin-13 (Imp13).

AFF2_HUMAN
NC score	0.010437 (rank : 220)	θ value	1.81305 (rank : 168)
Query Neighborhood Hits	251	Target Neighborhood Hits	218	Shared Neighborhood Hits	12
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

RT35_HUMAN
NC score	0.010393 (rank : 221)	θ value	2.36792 (rank : 182)
Query Neighborhood Hits	251	Target Neighborhood Hits	73	Shared Neighborhood Hits	3
SwissProt Accessions	P82673, Q32LZ1, Q6P4C6, Q7L1M6, Q96AI0, Q9H044, Q9HC14, Q9P1R5	Gene names	MRPS35, MRPS28
Domain Architecture	No domain graphic available
Description	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28).

ALKB1_HUMAN
NC score	0.010138 (rank : 222)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	251	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q13686, Q8TAU1, Q9ULA7	Gene names	ALKBH1, ABH, ALKBH
Domain Architecture	No domain graphic available
Description	Alkylated DNA repair protein alkB homolog 1.

PER3_HUMAN
NC score	0.010080 (rank : 223)	θ value	1.06291 (rank : 159)
Query Neighborhood Hits	251	Target Neighborhood Hits	479	Shared Neighborhood Hits	23
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CREB5_HUMAN
NC score	0.009919 (rank : 224)	θ value	0.62314 (rank : 146)
Query Neighborhood Hits	251	Target Neighborhood Hits	222	Shared Neighborhood Hits	2
SwissProt Accessions	Q02930, Q05886, Q06246	Gene names	CREB5, CREBPA
Domain Architecture
Description	cAMP response element-binding protein 5 (CRE-BPa).

MMP11_HUMAN
NC score	0.009660 (rank : 225)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	251	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	P24347, Q5FX24, Q6PEZ6, Q9UC26	Gene names	MMP11, STMY3
Domain Architecture
Description	Stromelysin-3 precursor (EC 3.4.24.-) (ST3) (SL-3) (Matrix metalloproteinase-11) (MMP-11).

ZCH14_HUMAN
NC score	0.009389 (rank : 226)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	251	Target Neighborhood Hits	117	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WYQ9, O60324, Q9UFP0	Gene names	ZCCHC14, KIAA0579
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 14 (BDG-29).

RAI1_MOUSE
NC score	0.009294 (rank : 227)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	251	Target Neighborhood Hits	344	Shared Neighborhood Hits	17
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TITIN_HUMAN
NC score	0.009248 (rank : 228)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	251	Target Neighborhood Hits	2923	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TM16H_HUMAN
NC score	0.009016 (rank : 229)	θ value	2.36792 (rank : 185)
Query Neighborhood Hits	251	Target Neighborhood Hits	139	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCE9	Gene names	TMEM16H, KIAA1623
Domain Architecture	No domain graphic available
Description	Transmembrane protein 16H.

TAF9_MOUSE
NC score	0.009011 (rank : 230)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	251	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

APBB1_HUMAN
NC score	0.008838 (rank : 231)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	251	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	O00213, Q96A93	Gene names	APBB1, FE65
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family B member 1 (Fe65 protein).

MMP10_MOUSE
NC score	0.008435 (rank : 232)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	251	Target Neighborhood Hits	57	Shared Neighborhood Hits	12
SwissProt Accessions	O55123	Gene names	Mmp10
Domain Architecture
Description	Stromelysin-2 precursor (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2) (SL-2).

FANCJ_MOUSE
NC score	0.008382 (rank : 233)	θ value	1.38821 (rank : 164)
Query Neighborhood Hits	251	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

RGS3_MOUSE
NC score	0.008230 (rank : 234)	θ value	0.47712 (rank : 144)
Query Neighborhood Hits	251	Target Neighborhood Hits	1621	Shared Neighborhood Hits	47
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

AFF2_MOUSE
NC score	0.008182 (rank : 235)	θ value	8.99809 (rank : 231)
Query Neighborhood Hits	251	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

PRG3_HUMAN
NC score	0.007964 (rank : 236)	θ value	1.81305 (rank : 175)
Query Neighborhood Hits	251	Target Neighborhood Hits	74	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2Y8	Gene names	PRG3, MBPH
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein homolog) (Prepro-major basic protein homolog) (Prepro-MBPH).

MUC1_HUMAN
NC score	0.007929 (rank : 237)	θ value	1.06291 (rank : 157)
Query Neighborhood Hits	251	Target Neighborhood Hits	975	Shared Neighborhood Hits	31
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CT012_HUMAN
NC score	0.007913 (rank : 238)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	251	Target Neighborhood Hits	205	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

MEP1B_MOUSE
NC score	0.007354 (rank : 239)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	251	Target Neighborhood Hits	127	Shared Neighborhood Hits	8
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

CSPG3_HUMAN
NC score	0.007350 (rank : 240)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	251	Target Neighborhood Hits	676	Shared Neighborhood Hits	34
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CCNT2_HUMAN
NC score	0.007320 (rank : 241)	θ value	1.81305 (rank : 169)
Query Neighborhood Hits	251	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	O60583, O60582, Q5I1Y0	Gene names	CCNT2
Domain Architecture
Description	Cyclin-T2 (CycT2).

CN037_HUMAN
NC score	0.007145 (rank : 242)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	251	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

PKHA3_MOUSE
NC score	0.006768 (rank : 243)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	251	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

TCF7_MOUSE
NC score	0.006551 (rank : 244)	θ value	1.06291 (rank : 162)
Query Neighborhood Hits	251	Target Neighborhood Hits	277	Shared Neighborhood Hits	8
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

SRRM2_MOUSE
NC score	0.005996 (rank : 245)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	251	Target Neighborhood Hits	1470	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TF3C1_HUMAN
NC score	0.005959 (rank : 246)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	251	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q12789, Q12838, Q9Y4W9	Gene names	GTF3C1
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 1 (Transcription factor IIIC-subunit alpha) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit).

COHA1_HUMAN
NC score	0.005850 (rank : 247)	θ value	8.99809 (rank : 233)
Query Neighborhood Hits	251	Target Neighborhood Hits	400	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

SH2D5_MOUSE
NC score	0.005837 (rank : 248)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	251	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	Q8JZW5	Gene names	Sh2d5
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 5.

NCOA2_HUMAN
NC score	0.005823 (rank : 249)	θ value	0.813845 (rank : 153)
Query Neighborhood Hits	251	Target Neighborhood Hits	281	Shared Neighborhood Hits	11
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

TTLL5_HUMAN
NC score	0.005137 (rank : 250)	θ value	2.36792 (rank : 186)
Query Neighborhood Hits	251	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

PF21B_MOUSE
NC score	0.005013 (rank : 251)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	251	Target Neighborhood Hits	278	Shared Neighborhood Hits	14
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MEP1B_HUMAN
NC score	0.004779 (rank : 252)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	251	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MAML1_HUMAN
NC score	0.004588 (rank : 253)	θ value	8.99809 (rank : 240)
Query Neighborhood Hits	251	Target Neighborhood Hits	228	Shared Neighborhood Hits	13
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MAP1A_HUMAN
NC score	0.004414 (rank : 254)	θ value	2.36792 (rank : 180)
Query Neighborhood Hits	251	Target Neighborhood Hits	1626	Shared Neighborhood Hits	32
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

GP1BA_HUMAN
NC score	0.004390 (rank : 255)	θ value	0.279714 (rank : 137)
Query Neighborhood Hits	251	Target Neighborhood Hits	407	Shared Neighborhood Hits	13
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

RXRB_HUMAN
NC score	0.003566 (rank : 256)	θ value	2.36792 (rank : 183)
Query Neighborhood Hits	251	Target Neighborhood Hits	280	Shared Neighborhood Hits	13
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

BAP1_HUMAN
NC score	0.003461 (rank : 257)	θ value	8.99809 (rank : 232)
Query Neighborhood Hits	251	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

TARA_HUMAN
NC score	0.003348 (rank : 258)	θ value	2.36792 (rank : 184)
Query Neighborhood Hits	251	Target Neighborhood Hits	1626	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SMG1_MOUSE
NC score	0.003119 (rank : 259)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	251	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

ELK4_HUMAN
NC score	0.003071 (rank : 260)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	251	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

CCD37_HUMAN
NC score	0.002736 (rank : 261)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	251	Target Neighborhood Hits	248	Shared Neighborhood Hits	3
SwissProt Accessions	Q494V2, Q494V1, Q494V4, Q8N838	Gene names	CCDC37
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 37.

SOX30_HUMAN
NC score	0.002670 (rank : 262)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	251	Target Neighborhood Hits	305	Shared Neighborhood Hits	12
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

SMG1_HUMAN
NC score	0.002574 (rank : 263)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	251	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

DNM3A_HUMAN
NC score	0.002330 (rank : 264)	θ value	8.99809 (rank : 234)
Query Neighborhood Hits	251	Target Neighborhood Hits	104	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

PLMN_HUMAN
NC score	0.001614 (rank : 265)	θ value	0.813845 (rank : 154)
Query Neighborhood Hits	251	Target Neighborhood Hits	204	Shared Neighborhood Hits	5
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

CEND1_MOUSE
NC score	0.001497 (rank : 266)	θ value	2.36792 (rank : 177)
Query Neighborhood Hits	251	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

MEFV_HUMAN
NC score	0.001474 (rank : 267)	θ value	0.813845 (rank : 151)
Query Neighborhood Hits	251	Target Neighborhood Hits	431	Shared Neighborhood Hits	11
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TCPH_HUMAN
NC score	0.001082 (rank : 268)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	251	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q99832, O14871	Gene names	CCT7, CCTH, NIP7-1
Domain Architecture
Description	T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (HIV-1 Nef- interacting protein).

SKIL_MOUSE
NC score	0.000878 (rank : 269)	θ value	1.06291 (rank : 161)
Query Neighborhood Hits	251	Target Neighborhood Hits	719	Shared Neighborhood Hits	5
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

PLMN_MOUSE
NC score	0.000820 (rank : 270)	θ value	1.06291 (rank : 160)
Query Neighborhood Hits	251	Target Neighborhood Hits	208	Shared Neighborhood Hits	5
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

DAAM1_MOUSE
NC score	0.000489 (rank : 271)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	251	Target Neighborhood Hits	443	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BPM0, Q80Y68, Q9CQQ2	Gene names	Daam1
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

MBB1A_HUMAN
NC score	0.000283 (rank : 272)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	251	Target Neighborhood Hits	665	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

FINC_MOUSE
NC score	0.000265 (rank : 273)	θ value	6.88961 (rank : 219)
Query Neighborhood Hits	251	Target Neighborhood Hits	309	Shared Neighborhood Hits	14
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

BRWD1_MOUSE
NC score	-0.000255 (rank : 274)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	251	Target Neighborhood Hits	478	Shared Neighborhood Hits	5
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

HGFL_HUMAN
NC score	-0.000665 (rank : 275)	θ value	8.99809 (rank : 236)
Query Neighborhood Hits	251	Target Neighborhood Hits	190	Shared Neighborhood Hits	5
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

JIP3_HUMAN
NC score	-0.000952 (rank : 276)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	251	Target Neighborhood Hits	1039	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

SPA3K_MOUSE
NC score	-0.001925 (rank : 277)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	251	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	P07759, Q91W80, Q91X80	Gene names	Serpina3k, Mcm2, Spi2
Domain Architecture
Description	Serine protease inhibitor A3K precursor (Contrapsin) (Serpin A3K).

ANR11_HUMAN
NC score	-0.003302 (rank : 278)	θ value	6.88961 (rank : 217)
Query Neighborhood Hits	251	Target Neighborhood Hits	1289	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

LGR5_MOUSE
NC score	-0.004211 (rank : 279)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	251	Target Neighborhood Hits	484	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1P4	Gene names	Lgr5, Fex, Gpr49
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 5 precursor (G-protein coupled receptor 49) (Orphan G-protein coupled receptor FEX).

EPHAA_HUMAN
NC score	-0.004515 (rank : 280)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	251	Target Neighborhood Hits	960	Shared Neighborhood Hits	10
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

PCNT_HUMAN
NC score	-0.006725 (rank : 281)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	251	Target Neighborhood Hits	1551	Shared Neighborhood Hits	15
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

ZN131_HUMAN
NC score	-0.009022 (rank : 282)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	251	Target Neighborhood Hits	833	Shared Neighborhood Hits	2
SwissProt Accessions	P52739, Q6PIF0	Gene names	ZNF131
Domain Architecture	No domain graphic available
Description	Zinc finger protein 131.

K0999_MOUSE
NC score	-0.009145 (rank : 283)	θ value	8.99809 (rank : 237)
Query Neighborhood Hits	251	Target Neighborhood Hits	931	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).