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Network neighborhood for query Sequence : CO8A_MOUSE

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CO8A_MOUSE
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CO8A_HUMAN
θ value	0 (rank : 1)	NC score	0.983998 (rank : 2)
Query Neighborhood Hits	182	Target Neighborhood Hits	200	Shared Neighborhood Hits	159
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	182	Target Neighborhood Hits	182	Shared Neighborhood Hits	182
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	4.95767e-99 (rank : 3)	NC score	0.942575 (rank : 4)
Query Neighborhood Hits	182	Target Neighborhood Hits	199	Shared Neighborhood Hits	152
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	1.76329e-96 (rank : 4)	NC score	0.950028 (rank : 3)
Query Neighborhood Hits	182	Target Neighborhood Hits	224	Shared Neighborhood Hits	162
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO6_HUMAN
θ value	1.10959e-82 (rank : 5)	NC score	0.870011 (rank : 5)
Query Neighborhood Hits	182	Target Neighborhood Hits	331	Shared Neighborhood Hits	163
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	7.97034e-73 (rank : 6)	NC score	0.842269 (rank : 6)
Query Neighborhood Hits	182	Target Neighborhood Hits	278	Shared Neighborhood Hits	156
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO9_MOUSE
θ value	2.3998e-69 (rank : 7)	NC score	0.832474 (rank : 7)
Query Neighborhood Hits	182	Target Neighborhood Hits	153	Shared Neighborhood Hits	108
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CO9_HUMAN
θ value	5.7252e-63 (rank : 8)	NC score	0.816197 (rank : 8)
Query Neighborhood Hits	182	Target Neighborhood Hits	147	Shared Neighborhood Hits	96
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

PERF_MOUSE
θ value	8.38298e-14 (rank : 9)	NC score	0.443990 (rank : 16)
Query Neighborhood Hits	182	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

PERF_HUMAN
θ value	2.69671e-12 (rank : 10)	NC score	0.406534 (rank : 51)
Query Neighborhood Hits	182	Target Neighborhood Hits	48	Shared Neighborhood Hits	19
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

ATS13_HUMAN
θ value	2.52405e-10 (rank : 11)	NC score	0.464448 (rank : 12)
Query Neighborhood Hits	182	Target Neighborhood Hits	238	Shared Neighborhood Hits	71
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

SEM5A_HUMAN
θ value	2.13673e-09 (rank : 12)	NC score	0.350851 (rank : 61)
Query Neighborhood Hits	182	Target Neighborhood Hits	177	Shared Neighborhood Hits	86
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	2.79066e-09 (rank : 13)	NC score	0.345775 (rank : 65)
Query Neighborhood Hits	182	Target Neighborhood Hits	162	Shared Neighborhood Hits	70
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATS13_MOUSE
θ value	3.64472e-09 (rank : 14)	NC score	0.456106 (rank : 13)
Query Neighborhood Hits	182	Target Neighborhood Hits	227	Shared Neighborhood Hits	75
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

TSP2_MOUSE
θ value	3.08544e-08 (rank : 15)	NC score	0.423650 (rank : 32)
Query Neighborhood Hits	182	Target Neighborhood Hits	352	Shared Neighborhood Hits	126
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATS17_HUMAN
θ value	4.0297e-08 (rank : 16)	NC score	0.417977 (rank : 41)
Query Neighborhood Hits	182	Target Neighborhood Hits	194	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

TSP2_HUMAN
θ value	5.26297e-08 (rank : 17)	NC score	0.419240 (rank : 40)
Query Neighborhood Hits	182	Target Neighborhood Hits	359	Shared Neighborhood Hits	122
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATS4_MOUSE
θ value	6.87365e-08 (rank : 18)	NC score	0.428173 (rank : 25)
Query Neighborhood Hits	182	Target Neighborhood Hits	145	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

HMCN1_HUMAN
θ value	6.87365e-08 (rank : 19)	NC score	0.276034 (rank : 97)
Query Neighborhood Hits	182	Target Neighborhood Hits	983	Shared Neighborhood Hits	132
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

SSPO_MOUSE
θ value	6.87365e-08 (rank : 20)	NC score	0.491467 (rank : 11)
Query Neighborhood Hits	182	Target Neighborhood Hits	800	Shared Neighborhood Hits	169
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ATS20_HUMAN
θ value	1.99992e-07 (rank : 21)	NC score	0.420524 (rank : 36)
Query Neighborhood Hits	182	Target Neighborhood Hits	192	Shared Neighborhood Hits	79
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS8_HUMAN
θ value	2.61198e-07 (rank : 22)	NC score	0.437645 (rank : 18)
Query Neighborhood Hits	182	Target Neighborhood Hits	145	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

LRP4_MOUSE
θ value	2.61198e-07 (rank : 23)	NC score	0.335941 (rank : 72)
Query Neighborhood Hits	182	Target Neighborhood Hits	351	Shared Neighborhood Hits	116
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

TSP1_HUMAN
θ value	2.61198e-07 (rank : 24)	NC score	0.417191 (rank : 42)
Query Neighborhood Hits	182	Target Neighborhood Hits	389	Shared Neighborhood Hits	129
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	2.61198e-07 (rank : 25)	NC score	0.416012 (rank : 45)
Query Neighborhood Hits	182	Target Neighborhood Hits	396	Shared Neighborhood Hits	130
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

UNC5A_MOUSE
θ value	2.61198e-07 (rank : 26)	NC score	0.448411 (rank : 14)
Query Neighborhood Hits	182	Target Neighborhood Hits	203	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ATS4_HUMAN
θ value	3.41135e-07 (rank : 27)	NC score	0.426562 (rank : 27)
Query Neighborhood Hits	182	Target Neighborhood Hits	138	Shared Neighborhood Hits	74
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

SEM5B_MOUSE
θ value	3.41135e-07 (rank : 28)	NC score	0.345894 (rank : 64)
Query Neighborhood Hits	182	Target Neighborhood Hits	190	Shared Neighborhood Hits	82
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

ATS16_HUMAN
θ value	4.45536e-07 (rank : 29)	NC score	0.424067 (rank : 31)
Query Neighborhood Hits	182	Target Neighborhood Hits	208	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

LRP4_HUMAN
θ value	4.45536e-07 (rank : 30)	NC score	0.337132 (rank : 71)
Query Neighborhood Hits	182	Target Neighborhood Hits	355	Shared Neighborhood Hits	114
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

ATS20_MOUSE
θ value	5.81887e-07 (rank : 31)	NC score	0.426413 (rank : 28)
Query Neighborhood Hits	182	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS14_HUMAN
θ value	7.59969e-07 (rank : 32)	NC score	0.412517 (rank : 49)
Query Neighborhood Hits	182	Target Neighborhood Hits	382	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS5_HUMAN
θ value	7.59969e-07 (rank : 33)	NC score	0.408940 (rank : 50)
Query Neighborhood Hits	182	Target Neighborhood Hits	141	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

ATS12_MOUSE
θ value	9.92553e-07 (rank : 34)	NC score	0.416132 (rank : 44)
Query Neighborhood Hits	182	Target Neighborhood Hits	220	Shared Neighborhood Hits	71
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

SEM5B_HUMAN
θ value	9.92553e-07 (rank : 35)	NC score	0.342734 (rank : 69)
Query Neighborhood Hits	182	Target Neighborhood Hits	178	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ATS1_HUMAN
θ value	1.29631e-06 (rank : 36)	NC score	0.430513 (rank : 23)
Query Neighborhood Hits	182	Target Neighborhood Hits	159	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS8_MOUSE
θ value	1.29631e-06 (rank : 37)	NC score	0.445789 (rank : 15)
Query Neighborhood Hits	182	Target Neighborhood Hits	139	Shared Neighborhood Hits	71
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

LRP1_HUMAN
θ value	1.29631e-06 (rank : 38)	NC score	0.315332 (rank : 87)
Query Neighborhood Hits	182	Target Neighborhood Hits	617	Shared Neighborhood Hits	124
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

SORL_HUMAN
θ value	1.29631e-06 (rank : 39)	NC score	0.324534 (rank : 81)
Query Neighborhood Hits	182	Target Neighborhood Hits	440	Shared Neighborhood Hits	109
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

UNC5C_HUMAN
θ value	1.29631e-06 (rank : 40)	NC score	0.431489 (rank : 21)
Query Neighborhood Hits	182	Target Neighborhood Hits	226	Shared Neighborhood Hits	71
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	1.29631e-06 (rank : 41)	NC score	0.430607 (rank : 22)
Query Neighborhood Hits	182	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

ATS16_MOUSE
θ value	1.69304e-06 (rank : 42)	NC score	0.420449 (rank : 37)
Query Neighborhood Hits	182	Target Neighborhood Hits	179	Shared Neighborhood Hits	70
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS12_HUMAN
θ value	2.21117e-06 (rank : 43)	NC score	0.413094 (rank : 47)
Query Neighborhood Hits	182	Target Neighborhood Hits	251	Shared Neighborhood Hits	69
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS1_MOUSE
θ value	2.21117e-06 (rank : 44)	NC score	0.428917 (rank : 24)
Query Neighborhood Hits	182	Target Neighborhood Hits	158	Shared Neighborhood Hits	72
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS15_HUMAN
θ value	2.88788e-06 (rank : 45)	NC score	0.427442 (rank : 26)
Query Neighborhood Hits	182	Target Neighborhood Hits	151	Shared Neighborhood Hits	69
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS18_HUMAN
θ value	2.88788e-06 (rank : 46)	NC score	0.423105 (rank : 33)
Query Neighborhood Hits	182	Target Neighborhood Hits	169	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS3_HUMAN
θ value	2.88788e-06 (rank : 47)	NC score	0.419793 (rank : 38)
Query Neighborhood Hits	182	Target Neighborhood Hits	179	Shared Neighborhood Hits	70
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS5_MOUSE
θ value	2.88788e-06 (rank : 48)	NC score	0.420835 (rank : 35)
Query Neighborhood Hits	182	Target Neighborhood Hits	147	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

SORL_MOUSE
θ value	2.88788e-06 (rank : 49)	NC score	0.325975 (rank : 80)
Query Neighborhood Hits	182	Target Neighborhood Hits	439	Shared Neighborhood Hits	104
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

ST14_HUMAN
θ value	2.88788e-06 (rank : 50)	NC score	0.206615 (rank : 106)
Query Neighborhood Hits	182	Target Neighborhood Hits	409	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

UNC5B_HUMAN
θ value	2.88788e-06 (rank : 51)	NC score	0.437075 (rank : 19)
Query Neighborhood Hits	182	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	2.88788e-06 (rank : 52)	NC score	0.439059 (rank : 17)
Query Neighborhood Hits	182	Target Neighborhood Hits	226	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

LDLR_MOUSE
θ value	3.77169e-06 (rank : 53)	NC score	0.334514 (rank : 73)
Query Neighborhood Hits	182	Target Neighborhood Hits	382	Shared Neighborhood Hits	111
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_MOUSE
θ value	4.92598e-06 (rank : 54)	NC score	0.315711 (rank : 86)
Query Neighborhood Hits	182	Target Neighborhood Hits	606	Shared Neighborhood Hits	124
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

UNC5A_HUMAN
θ value	6.43352e-06 (rank : 55)	NC score	0.404272 (rank : 52)
Query Neighborhood Hits	182	Target Neighborhood Hits	198	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ATS9_HUMAN
θ value	8.40245e-06 (rank : 56)	NC score	0.431666 (rank : 20)
Query Neighborhood Hits	182	Target Neighborhood Hits	219	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

LDLR_HUMAN
θ value	8.40245e-06 (rank : 57)	NC score	0.328811 (rank : 77)
Query Neighborhood Hits	182	Target Neighborhood Hits	375	Shared Neighborhood Hits	109
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

UNC5D_HUMAN
θ value	1.09739e-05 (rank : 58)	NC score	0.417029 (rank : 43)
Query Neighborhood Hits	182	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	1.09739e-05 (rank : 59)	NC score	0.414643 (rank : 46)
Query Neighborhood Hits	182	Target Neighborhood Hits	268	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

VLDLR_HUMAN
θ value	1.09739e-05 (rank : 60)	NC score	0.334470 (rank : 74)
Query Neighborhood Hits	182	Target Neighborhood Hits	383	Shared Neighborhood Hits	110
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

TMPS6_HUMAN
θ value	1.43324e-05 (rank : 61)	NC score	0.158787 (rank : 119)
Query Neighborhood Hits	182	Target Neighborhood Hits	338	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ATS18_MOUSE
θ value	2.44474e-05 (rank : 62)	NC score	0.425100 (rank : 30)
Query Neighborhood Hits	182	Target Neighborhood Hits	163	Shared Neighborhood Hits	68
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

LRP1B_HUMAN
θ value	2.44474e-05 (rank : 63)	NC score	0.316134 (rank : 85)
Query Neighborhood Hits	182	Target Neighborhood Hits	602	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

VLDLR_MOUSE
θ value	2.44474e-05 (rank : 64)	NC score	0.330652 (rank : 75)
Query Neighborhood Hits	182	Target Neighborhood Hits	360	Shared Neighborhood Hits	108
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ATS6_HUMAN
θ value	3.19293e-05 (rank : 65)	NC score	0.419720 (rank : 39)
Query Neighborhood Hits	182	Target Neighborhood Hits	141	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

CORIN_HUMAN
θ value	3.19293e-05 (rank : 66)	NC score	0.210007 (rank : 105)
Query Neighborhood Hits	182	Target Neighborhood Hits	453	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

PROP_MOUSE
θ value	4.1701e-05 (rank : 67)	NC score	0.499682 (rank : 9)
Query Neighborhood Hits	182	Target Neighborhood Hits	165	Shared Neighborhood Hits	77
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

ST14_MOUSE
θ value	5.44631e-05 (rank : 68)	NC score	0.201079 (rank : 108)
Query Neighborhood Hits	182	Target Neighborhood Hits	419	Shared Neighborhood Hits	101
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ATS7_HUMAN
θ value	9.29e-05 (rank : 69)	NC score	0.412919 (rank : 48)
Query Neighborhood Hits	182	Target Neighborhood Hits	169	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

BAI1_HUMAN
θ value	0.000121331 (rank : 70)	NC score	0.343102 (rank : 68)
Query Neighborhood Hits	182	Target Neighborhood Hits	375	Shared Neighborhood Hits	76
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	0.000121331 (rank : 71)	NC score	0.343109 (rank : 67)
Query Neighborhood Hits	182	Target Neighborhood Hits	340	Shared Neighborhood Hits	74
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

PROP_HUMAN
θ value	0.000121331 (rank : 72)	NC score	0.492034 (rank : 10)
Query Neighborhood Hits	182	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

CORIN_MOUSE
θ value	0.000158464 (rank : 73)	NC score	0.205487 (rank : 107)
Query Neighborhood Hits	182	Target Neighborhood Hits	451	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LRP8_MOUSE
θ value	0.000158464 (rank : 74)	NC score	0.321926 (rank : 83)
Query Neighborhood Hits	182	Target Neighborhood Hits	385	Shared Neighborhood Hits	112
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

ATS2_HUMAN
θ value	0.00020696 (rank : 75)	NC score	0.425114 (rank : 29)
Query Neighborhood Hits	182	Target Neighborhood Hits	179	Shared Neighborhood Hits	73
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

LRP2_HUMAN
θ value	0.000270298 (rank : 76)	NC score	0.322266 (rank : 82)
Query Neighborhood Hits	182	Target Neighborhood Hits	573	Shared Neighborhood Hits	123
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ATS2_MOUSE
θ value	0.00035302 (rank : 77)	NC score	0.421825 (rank : 34)
Query Neighborhood Hits	182	Target Neighborhood Hits	179	Shared Neighborhood Hits	72
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

TMPS6_MOUSE
θ value	0.00035302 (rank : 78)	NC score	0.148834 (rank : 128)
Query Neighborhood Hits	182	Target Neighborhood Hits	341	Shared Neighborhood Hits	84
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

BAI2_HUMAN
θ value	0.000461057 (rank : 79)	NC score	0.326845 (rank : 78)
Query Neighborhood Hits	182	Target Neighborhood Hits	332	Shared Neighborhood Hits	78
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	0.000461057 (rank : 80)	NC score	0.326552 (rank : 79)
Query Neighborhood Hits	182	Target Neighborhood Hits	323	Shared Neighborhood Hits	76
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

PGBM_HUMAN
θ value	0.000602161 (rank : 81)	NC score	0.174643 (rank : 113)
Query Neighborhood Hits	182	Target Neighborhood Hits	1113	Shared Neighborhood Hits	126
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	0.000786445 (rank : 82)	NC score	0.176188 (rank : 112)
Query Neighborhood Hits	182	Target Neighborhood Hits	1073	Shared Neighborhood Hits	122
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LRP8_HUMAN
θ value	0.00228821 (rank : 83)	NC score	0.320709 (rank : 84)
Query Neighborhood Hits	182	Target Neighborhood Hits	346	Shared Neighborhood Hits	109
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

TMPS7_MOUSE
θ value	0.00228821 (rank : 84)	NC score	0.160433 (rank : 117)
Query Neighborhood Hits	182	Target Neighborhood Hits	275	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

LRP5_HUMAN
θ value	0.00298849 (rank : 85)	NC score	0.309043 (rank : 91)
Query Neighborhood Hits	182	Target Neighborhood Hits	224	Shared Neighborhood Hits	80
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

BAI3_HUMAN
θ value	0.00390308 (rank : 86)	NC score	0.339977 (rank : 70)
Query Neighborhood Hits	182	Target Neighborhood Hits	246	Shared Neighborhood Hits	73
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CD320_HUMAN
θ value	0.00390308 (rank : 87)	NC score	0.380884 (rank : 54)
Query Neighborhood Hits	182	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

LRP3_HUMAN
θ value	0.00390308 (rank : 88)	NC score	0.303504 (rank : 94)
Query Neighborhood Hits	182	Target Neighborhood Hits	280	Shared Neighborhood Hits	84
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

CFAI_HUMAN
θ value	0.00509761 (rank : 89)	NC score	0.160002 (rank : 118)
Query Neighborhood Hits	182	Target Neighborhood Hits	289	Shared Neighborhood Hits	77
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

LRP6_HUMAN
θ value	0.00509761 (rank : 90)	NC score	0.314925 (rank : 88)
Query Neighborhood Hits	182	Target Neighborhood Hits	235	Shared Neighborhood Hits	85
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	0.00509761 (rank : 91)	NC score	0.314748 (rank : 89)
Query Neighborhood Hits	182	Target Neighborhood Hits	232	Shared Neighborhood Hits	83
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

NOTC1_HUMAN
θ value	0.00509761 (rank : 92)	NC score	0.141362 (rank : 140)
Query Neighborhood Hits	182	Target Neighborhood Hits	906	Shared Neighborhood Hits	93
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

BAI3_MOUSE
θ value	0.00665767 (rank : 93)	NC score	0.345523 (rank : 66)
Query Neighborhood Hits	182	Target Neighborhood Hits	250	Shared Neighborhood Hits	77
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

LRP10_HUMAN
θ value	0.00665767 (rank : 94)	NC score	0.311437 (rank : 90)
Query Neighborhood Hits	182	Target Neighborhood Hits	197	Shared Neighborhood Hits	78
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	0.00869519 (rank : 95)	NC score	0.307453 (rank : 92)
Query Neighborhood Hits	182	Target Neighborhood Hits	169	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_MOUSE
θ value	0.0113563 (rank : 96)	NC score	0.284697 (rank : 95)
Query Neighborhood Hits	182	Target Neighborhood Hits	180	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

CFAI_MOUSE
θ value	0.0148317 (rank : 97)	NC score	0.150457 (rank : 126)
Query Neighborhood Hits	182	Target Neighborhood Hits	290	Shared Neighborhood Hits	75
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

LRP12_HUMAN
θ value	0.0148317 (rank : 98)	NC score	0.282840 (rank : 96)
Query Neighborhood Hits	182	Target Neighborhood Hits	205	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

TMPS7_HUMAN
θ value	0.0148317 (rank : 99)	NC score	0.157841 (rank : 121)
Query Neighborhood Hits	182	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

CILP2_HUMAN
θ value	0.0330416 (rank : 100)	NC score	0.258794 (rank : 100)
Query Neighborhood Hits	182	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

NOTC1_MOUSE
θ value	0.0330416 (rank : 101)	NC score	0.145070 (rank : 132)
Query Neighborhood Hits	182	Target Neighborhood Hits	916	Shared Neighborhood Hits	92
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LRP5_MOUSE
θ value	0.0431538 (rank : 102)	NC score	0.307003 (rank : 93)
Query Neighborhood Hits	182	Target Neighborhood Hits	236	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

MFRP_MOUSE
θ value	0.0431538 (rank : 103)	NC score	0.153151 (rank : 124)
Query Neighborhood Hits	182	Target Neighborhood Hits	166	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

RXFP2_HUMAN
θ value	0.0736092 (rank : 104)	NC score	0.093065 (rank : 268)
Query Neighborhood Hits	182	Target Neighborhood Hits	736	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

DNER_HUMAN
θ value	0.0961366 (rank : 105)	NC score	0.135534 (rank : 145)
Query Neighborhood Hits	182	Target Neighborhood Hits	460	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

JAG1_MOUSE
θ value	0.0961366 (rank : 106)	NC score	0.142888 (rank : 136)
Query Neighborhood Hits	182	Target Neighborhood Hits	518	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

TMPS3_HUMAN
θ value	0.0961366 (rank : 107)	NC score	0.087304 (rank : 284)
Query Neighborhood Hits	182	Target Neighborhood Hits	245	Shared Neighborhood Hits	63
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

DNER_MOUSE
θ value	0.125558 (rank : 108)	NC score	0.129937 (rank : 152)
Query Neighborhood Hits	182	Target Neighborhood Hits	413	Shared Neighborhood Hits	76
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

ENTK_HUMAN
θ value	0.125558 (rank : 109)	NC score	0.112106 (rank : 202)
Query Neighborhood Hits	182	Target Neighborhood Hits	310	Shared Neighborhood Hits	66
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

JAG1_HUMAN
θ value	0.125558 (rank : 110)	NC score	0.144017 (rank : 135)
Query Neighborhood Hits	182	Target Neighborhood Hits	514	Shared Neighborhood Hits	83
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

NOTC4_HUMAN
θ value	0.125558 (rank : 111)	NC score	0.132658 (rank : 149)
Query Neighborhood Hits	182	Target Neighborhood Hits	905	Shared Neighborhood Hits	91
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

RXFP2_MOUSE
θ value	0.125558 (rank : 112)	NC score	0.082367 (rank : 306)
Query Neighborhood Hits	182	Target Neighborhood Hits	760	Shared Neighborhood Hits	63
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

NOTC4_MOUSE
θ value	0.21417 (rank : 113)	NC score	0.123699 (rank : 160)
Query Neighborhood Hits	182	Target Neighborhood Hits	872	Shared Neighborhood Hits	90
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

FATH_HUMAN
θ value	0.279714 (rank : 114)	NC score	0.065894 (rank : 359)
Query Neighborhood Hits	182	Target Neighborhood Hits	570	Shared Neighborhood Hits	73
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TMPS9_HUMAN
θ value	0.279714 (rank : 115)	NC score	0.097602 (rank : 251)
Query Neighborhood Hits	182	Target Neighborhood Hits	276	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

RXFP1_HUMAN
θ value	0.365318 (rank : 116)	NC score	0.072330 (rank : 339)
Query Neighborhood Hits	182	Target Neighborhood Hits	816	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HBX9	Gene names	RXFP1, LGR7
Domain Architecture
Description	Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-rich repeat-containing G-protein coupled receptor 7).

DLK_HUMAN
θ value	0.47712 (rank : 117)	NC score	0.127394 (rank : 156)
Query Neighborhood Hits	182	Target Neighborhood Hits	401	Shared Neighborhood Hits	75
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

FAM5B_HUMAN
θ value	0.47712 (rank : 118)	NC score	0.065733 (rank : 360)
Query Neighborhood Hits	182	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

NOTC2_HUMAN
θ value	0.47712 (rank : 119)	NC score	0.140704 (rank : 142)
Query Neighborhood Hits	182	Target Neighborhood Hits	1113	Shared Neighborhood Hits	96
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	0.47712 (rank : 120)	NC score	0.142189 (rank : 138)
Query Neighborhood Hits	182	Target Neighborhood Hits	1069	Shared Neighborhood Hits	97
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	0.47712 (rank : 121)	NC score	0.132542 (rank : 150)
Query Neighborhood Hits	182	Target Neighborhood Hits	1062	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	0.47712 (rank : 122)	NC score	0.133500 (rank : 147)
Query Neighborhood Hits	182	Target Neighborhood Hits	975	Shared Neighborhood Hits	108
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TNR26_MOUSE
θ value	0.47712 (rank : 123)	NC score	0.057749 (rank : 416)
Query Neighborhood Hits	182	Target Neighborhood Hits	106	Shared Neighborhood Hits	17
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

ATL3_HUMAN
θ value	0.62314 (rank : 124)	NC score	0.328979 (rank : 76)
Query Neighborhood Hits	182	Target Neighborhood Hits	414	Shared Neighborhood Hits	73
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

CR001_HUMAN
θ value	0.62314 (rank : 125)	NC score	0.226259 (rank : 102)
Query Neighborhood Hits	182	Target Neighborhood Hits	68	Shared Neighborhood Hits	52
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
θ value	0.62314 (rank : 126)	NC score	0.224233 (rank : 103)
Query Neighborhood Hits	182	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

DLL4_HUMAN
θ value	0.62314 (rank : 127)	NC score	0.141336 (rank : 141)
Query Neighborhood Hits	182	Target Neighborhood Hits	435	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

ENTK_MOUSE
θ value	0.62314 (rank : 128)	NC score	0.105323 (rank : 227)
Query Neighborhood Hits	182	Target Neighborhood Hits	338	Shared Neighborhood Hits	68
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

UROM_MOUSE
θ value	0.62314 (rank : 129)	NC score	0.100803 (rank : 241)
Query Neighborhood Hits	182	Target Neighborhood Hits	276	Shared Neighborhood Hits	66
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

JAG2_MOUSE
θ value	0.813845 (rank : 130)	NC score	0.144235 (rank : 134)
Query Neighborhood Hits	182	Target Neighborhood Hits	504	Shared Neighborhood Hits	90
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

ATL1_HUMAN
θ value	1.06291 (rank : 131)	NC score	0.361441 (rank : 57)
Query Neighborhood Hits	182	Target Neighborhood Hits	93	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
θ value	1.06291 (rank : 132)	NC score	0.357952 (rank : 58)
Query Neighborhood Hits	182	Target Neighborhood Hits	80	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATS19_MOUSE
θ value	1.06291 (rank : 133)	NC score	0.350427 (rank : 62)
Query Neighborhood Hits	182	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

CSPG2_HUMAN
θ value	1.06291 (rank : 134)	NC score	0.084446 (rank : 295)
Query Neighborhood Hits	182	Target Neighborhood Hits	681	Shared Neighborhood Hits	66
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	1.06291 (rank : 135)	NC score	0.084423 (rank : 296)
Query Neighborhood Hits	182	Target Neighborhood Hits	711	Shared Neighborhood Hits	68
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

DLL1_HUMAN
θ value	1.06291 (rank : 136)	NC score	0.145074 (rank : 131)
Query Neighborhood Hits	182	Target Neighborhood Hits	455	Shared Neighborhood Hits	93
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

FAM5B_MOUSE
θ value	1.06291 (rank : 137)	NC score	0.067000 (rank : 354)
Query Neighborhood Hits	182	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

SLIT2_HUMAN
θ value	1.06291 (rank : 138)	NC score	0.089739 (rank : 276)
Query Neighborhood Hits	182	Target Neighborhood Hits	708	Shared Neighborhood Hits	83
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

MFRP_HUMAN
θ value	1.38821 (rank : 139)	NC score	0.144554 (rank : 133)
Query Neighborhood Hits	182	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

C209D_MOUSE
θ value	1.81305 (rank : 140)	NC score	0.010624 (rank : 487)
Query Neighborhood Hits	182	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZW8, Q8VIK4	Gene names	Cd209d
Domain Architecture
Description	CD209 antigen-like protein D (DC-SIGN-related protein 3) (DC-SIGNR3).

FAM5C_MOUSE
θ value	1.81305 (rank : 141)	NC score	0.056507 (rank : 427)
Query Neighborhood Hits	182	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q499E0, Q8K0R9	Gene names	Fam5c
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor.

ITB4_HUMAN
θ value	1.81305 (rank : 142)	NC score	0.052379 (rank : 460)
Query Neighborhood Hits	182	Target Neighborhood Hits	458	Shared Neighborhood Hits	62
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

JAG2_HUMAN
θ value	1.81305 (rank : 143)	NC score	0.142485 (rank : 137)
Query Neighborhood Hits	182	Target Neighborhood Hits	491	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

LRP11_MOUSE
θ value	1.81305 (rank : 144)	NC score	0.219257 (rank : 104)
Query Neighborhood Hits	182	Target Neighborhood Hits	81	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

NETO1_HUMAN
θ value	1.81305 (rank : 145)	NC score	0.104396 (rank : 229)
Query Neighborhood Hits	182	Target Neighborhood Hits	110	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	1.81305 (rank : 146)	NC score	0.104186 (rank : 231)
Query Neighborhood Hits	182	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

TENN_HUMAN
θ value	1.81305 (rank : 147)	NC score	0.054994 (rank : 434)
Query Neighborhood Hits	182	Target Neighborhood Hits	453	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

DLL1_MOUSE
θ value	2.36792 (rank : 148)	NC score	0.141944 (rank : 139)
Query Neighborhood Hits	182	Target Neighborhood Hits	456	Shared Neighborhood Hits	90
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

FAM5C_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.055213 (rank : 432)
Query Neighborhood Hits	182	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q76B58, O95726	Gene names	FAM5C, DBCCR1L, DBCCR1L1
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor (DBCCR1-like protein 1).

TMPS9_MOUSE
θ value	2.36792 (rank : 150)	NC score	0.094368 (rank : 264)
Query Neighborhood Hits	182	Target Neighborhood Hits	296	Shared Neighborhood Hits	61
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

ATL5_HUMAN
θ value	3.0926 (rank : 151)	NC score	0.363867 (rank : 56)
Query Neighborhood Hits	182	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

CRUM1_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.131715 (rank : 151)
Query Neighborhood Hits	182	Target Neighborhood Hits	444	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

LRP11_HUMAN
θ value	3.0926 (rank : 153)	NC score	0.193548 (rank : 109)
Query Neighborhood Hits	182	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

SLIT2_MOUSE
θ value	3.0926 (rank : 154)	NC score	0.086330 (rank : 287)
Query Neighborhood Hits	182	Target Neighborhood Hits	684	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TMPS2_MOUSE
θ value	3.0926 (rank : 155)	NC score	0.084356 (rank : 297)
Query Neighborhood Hits	182	Target Neighborhood Hits	243	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

DOCK4_HUMAN
θ value	4.03905 (rank : 156)	NC score	0.011238 (rank : 486)
Query Neighborhood Hits	182	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_MOUSE
θ value	4.03905 (rank : 157)	NC score	0.011316 (rank : 485)
Query Neighborhood Hits	182	Target Neighborhood Hits	210	Shared Neighborhood Hits	7
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

IDD_HUMAN
θ value	4.03905 (rank : 158)	NC score	0.183188 (rank : 111)
Query Neighborhood Hits	182	Target Neighborhood Hits	127	Shared Neighborhood Hits	60
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

LAMB1_HUMAN
θ value	4.03905 (rank : 159)	NC score	0.060703 (rank : 392)
Query Neighborhood Hits	182	Target Neighborhood Hits	1018	Shared Neighborhood Hits	68
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SPON1_MOUSE
θ value	4.03905 (rank : 160)	NC score	0.383613 (rank : 53)
Query Neighborhood Hits	182	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

TMPS3_MOUSE
θ value	4.03905 (rank : 161)	NC score	0.076949 (rank : 326)
Query Neighborhood Hits	182	Target Neighborhood Hits	239	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

C209E_MOUSE
θ value	5.27518 (rank : 162)	NC score	0.008426 (rank : 488)
Query Neighborhood Hits	182	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZW7	Gene names	Cd209e
Domain Architecture
Description	CD209 antigen-like protein E (DC-SIGN-related protein 4) (DC-SIGNR4).

CRUM1_HUMAN
θ value	5.27518 (rank : 163)	NC score	0.135544 (rank : 144)
Query Neighborhood Hits	182	Target Neighborhood Hits	457	Shared Neighborhood Hits	86
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.129050 (rank : 154)
Query Neighborhood Hits	182	Target Neighborhood Hits	453	Shared Neighborhood Hits	77
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

FA9_HUMAN
θ value	5.27518 (rank : 165)	NC score	0.086318 (rank : 288)
Query Neighborhood Hits	182	Target Neighborhood Hits	421	Shared Neighborhood Hits	83
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FAM5A_HUMAN
θ value	5.27518 (rank : 166)	NC score	0.050905 (rank : 474)
Query Neighborhood Hits	182	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O60477, Q6IPV6, Q6P1A0, Q8WU22	Gene names	FAM5A, DBC1, DBCCR1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein).

FAM5A_MOUSE
θ value	5.27518 (rank : 167)	NC score	0.050831 (rank : 477)
Query Neighborhood Hits	182	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q920P3, Q80ZL2, Q812F0, Q8C1C9, Q920P4, Q9QXL0	Gene names	Fam5a, Brinp, Brinp1, Dbccr1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein homolog) (BMP/retinoic acid-inducible neural-specific protein 1).

HGFA_MOUSE
θ value	5.27518 (rank : 168)	NC score	0.080562 (rank : 312)
Query Neighborhood Hits	182	Target Neighborhood Hits	419	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LYAM2_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.057868 (rank : 414)
Query Neighborhood Hits	182	Target Neighborhood Hits	394	Shared Neighborhood Hits	67
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NAGPA_HUMAN
θ value	5.27518 (rank : 170)	NC score	0.076264 (rank : 327)
Query Neighborhood Hits	182	Target Neighborhood Hits	282	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

DLL4_MOUSE
θ value	6.88961 (rank : 171)	NC score	0.135975 (rank : 143)
Query Neighborhood Hits	182	Target Neighborhood Hits	440	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

HABP2_MOUSE
θ value	6.88961 (rank : 172)	NC score	0.097103 (rank : 254)
Query Neighborhood Hits	182	Target Neighborhood Hits	445	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LAMA5_MOUSE
θ value	6.88961 (rank : 173)	NC score	0.080154 (rank : 314)
Query Neighborhood Hits	182	Target Neighborhood Hits	828	Shared Neighborhood Hits	85
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LTB1L_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.123135 (rank : 163)
Query Neighborhood Hits	182	Target Neighborhood Hits	553	Shared Neighborhood Hits	88
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	6.88961 (rank : 175)	NC score	0.116548 (rank : 184)
Query Neighborhood Hits	182	Target Neighborhood Hits	502	Shared Neighborhood Hits	84
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SPON2_MOUSE
θ value	6.88961 (rank : 176)	NC score	0.094503 (rank : 261)
Query Neighborhood Hits	182	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

TENX_HUMAN
θ value	6.88961 (rank : 177)	NC score	0.118985 (rank : 172)
Query Neighborhood Hits	182	Target Neighborhood Hits	789	Shared Neighborhood Hits	100
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

DLK_MOUSE
θ value	8.99809 (rank : 178)	NC score	0.118727 (rank : 173)
Query Neighborhood Hits	182	Target Neighborhood Hits	374	Shared Neighborhood Hits	75
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

SPIT1_MOUSE
θ value	8.99809 (rank : 179)	NC score	0.145834 (rank : 130)
Query Neighborhood Hits	182	Target Neighborhood Hits	96	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPON1_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.373873 (rank : 55)
Query Neighborhood Hits	182	Target Neighborhood Hits	117	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

STAB2_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.103004 (rank : 237)
Query Neighborhood Hits	182	Target Neighborhood Hits	534	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TENA_MOUSE
θ value	8.99809 (rank : 182)	NC score	0.110573 (rank : 206)
Query Neighborhood Hits	182	Target Neighborhood Hits	596	Shared Neighborhood Hits	90
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

AD26A_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.078612 (rank : 320)
Query Neighborhood Hits	182	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA10_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.068909 (rank : 347)
Query Neighborhood Hits	182	Target Neighborhood Hits	189	Shared Neighborhood Hits	55
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.062394 (rank : 381)
Query Neighborhood Hits	182	Target Neighborhood Hits	194	Shared Neighborhood Hits	49
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA11_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.082318 (rank : 307)
Query Neighborhood Hits	182	Target Neighborhood Hits	259	Shared Neighborhood Hits	72
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.092315 (rank : 271)
Query Neighborhood Hits	182	Target Neighborhood Hits	263	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA12_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.115097 (rank : 188)
Query Neighborhood Hits	182	Target Neighborhood Hits	224	Shared Neighborhood Hits	66
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA12_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.109691 (rank : 211)
Query Neighborhood Hits	182	Target Neighborhood Hits	474	Shared Neighborhood Hits	67
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.114263 (rank : 193)
Query Neighborhood Hits	182	Target Neighborhood Hits	288	Shared Neighborhood Hits	76
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.102950 (rank : 238)
Query Neighborhood Hits	182	Target Neighborhood Hits	324	Shared Neighborhood Hits	80
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.074801 (rank : 330)
Query Neighborhood Hits	182	Target Neighborhood Hits	223	Shared Neighborhood Hits	62
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.067677 (rank : 350)
Query Neighborhood Hits	182	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.050872 (rank : 475)
Query Neighborhood Hits	182	Target Neighborhood Hits	184	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA18_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.063667 (rank : 372)
Query Neighborhood Hits	182	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA19_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.123606 (rank : 161)
Query Neighborhood Hits	182	Target Neighborhood Hits	381	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.128776 (rank : 155)
Query Neighborhood Hits	182	Target Neighborhood Hits	315	Shared Neighborhood Hits	87
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA20_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.060862 (rank : 391)
Query Neighborhood Hits	182	Target Neighborhood Hits	143	Shared Neighborhood Hits	51
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.084185 (rank : 299)
Query Neighborhood Hits	182	Target Neighborhood Hits	181	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA21_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.092760 (rank : 270)
Query Neighborhood Hits	182	Target Neighborhood Hits	172	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA22_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.094483 (rank : 262)
Query Neighborhood Hits	182	Target Neighborhood Hits	211	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADA22_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.093454 (rank : 267)
Query Neighborhood Hits	182	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA23_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.093982 (rank : 266)
Query Neighborhood Hits	182	Target Neighborhood Hits	235	Shared Neighborhood Hits	78
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.096441 (rank : 256)
Query Neighborhood Hits	182	Target Neighborhood Hits	245	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA24_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.096168 (rank : 258)
Query Neighborhood Hits	182	Target Neighborhood Hits	230	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADA25_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.083652 (rank : 303)
Query Neighborhood Hits	182	Target Neighborhood Hits	213	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.121536 (rank : 167)
Query Neighborhood Hits	182	Target Neighborhood Hits	244	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA28_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.124293 (rank : 159)
Query Neighborhood Hits	182	Target Neighborhood Hits	241	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA29_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.082578 (rank : 305)
Query Neighborhood Hits	182	Target Neighborhood Hits	247	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA32_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.073091 (rank : 337)
Query Neighborhood Hits	182	Target Neighborhood Hits	216	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.067401 (rank : 352)
Query Neighborhood Hits	182	Target Neighborhood Hits	219	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA33_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.114416 (rank : 191)
Query Neighborhood Hits	182	Target Neighborhood Hits	264	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.103956 (rank : 232)
Query Neighborhood Hits	182	Target Neighborhood Hits	231	Shared Neighborhood Hits	65
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.065219 (rank : 363)
Query Neighborhood Hits	182	Target Neighborhood Hits	175	Shared Neighborhood Hits	67
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM2_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.083977 (rank : 301)
Query Neighborhood Hits	182	Target Neighborhood Hits	209	Shared Neighborhood Hits	78
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.119026 (rank : 171)
Query Neighborhood Hits	182	Target Neighborhood Hits	221	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.112247 (rank : 200)
Query Neighborhood Hits	182	Target Neighborhood Hits	200	Shared Neighborhood Hits	67
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM8_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.135494 (rank : 146)
Query Neighborhood Hits	182	Target Neighborhood Hits	327	Shared Neighborhood Hits	81
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.132788 (rank : 148)
Query Neighborhood Hits	182	Target Neighborhood Hits	326	Shared Neighborhood Hits	88
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.112197 (rank : 201)
Query Neighborhood Hits	182	Target Neighborhood Hits	243	Shared Neighborhood Hits	75
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.118278 (rank : 176)
Query Neighborhood Hits	182	Target Neighborhood Hits	325	Shared Neighborhood Hits	78
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADEC1_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.099774 (rank : 244)
Query Neighborhood Hits	182	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.078746 (rank : 319)
Query Neighborhood Hits	182	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADM1A_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.100518 (rank : 242)
Query Neighborhood Hits	182	Target Neighborhood Hits	230	Shared Neighborhood Hits	71
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.107132 (rank : 221)
Query Neighborhood Hits	182	Target Neighborhood Hits	236	Shared Neighborhood Hits	80
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

AGRIN_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.096976 (rank : 255)
Query Neighborhood Hits	182	Target Neighborhood Hits	582	Shared Neighborhood Hits	84
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ATL2_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.354569 (rank : 59)
Query Neighborhood Hits	182	Target Neighborhood Hits	125	Shared Neighborhood Hits	69
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.353947 (rank : 60)
Query Neighborhood Hits	182	Target Neighborhood Hits	137	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATRN_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.063219 (rank : 375)
Query Neighborhood Hits	182	Target Neighborhood Hits	525	Shared Neighborhood Hits	77
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.058389 (rank : 410)
Query Neighborhood Hits	182	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ATS19_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.349938 (rank : 63)
Query Neighborhood Hits	182	Target Neighborhood Hits	203	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

BMP1_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.060521 (rank : 394)
Query Neighborhood Hits	182	Target Neighborhood Hits	233	Shared Neighborhood Hits	55
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.061010 (rank : 389)
Query Neighborhood Hits	182	Target Neighborhood Hits	236	Shared Neighborhood Hits	56
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

C1QR1_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.112292 (rank : 198)
Query Neighborhood Hits	182	Target Neighborhood Hits	493	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.111086 (rank : 205)
Query Neighborhood Hits	182	Target Neighborhood Hits	342	Shared Neighborhood Hits	68
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1RA_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.067911 (rank : 349)
Query Neighborhood Hits	182	Target Neighborhood Hits	379	Shared Neighborhood Hits	69
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.065167 (rank : 365)
Query Neighborhood Hits	182	Target Neighborhood Hits	380	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.064316 (rank : 368)
Query Neighborhood Hits	182	Target Neighborhood Hits	364	Shared Neighborhood Hits	62
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.064650 (rank : 366)
Query Neighborhood Hits	182	Target Neighborhood Hits	359	Shared Neighborhood Hits	69
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CD248_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.084223 (rank : 298)
Query Neighborhood Hits	182	Target Neighborhood Hits	679	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.087704 (rank : 283)
Query Neighborhood Hits	182	Target Neighborhood Hits	578	Shared Neighborhood Hits	62
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.099437 (rank : 245)
Query Neighborhood Hits	182	Target Neighborhood Hits	353	Shared Neighborhood Hits	72
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.084564 (rank : 294)
Query Neighborhood Hits	182	Target Neighborhood Hits	295	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CELR1_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.052714 (rank : 458)
Query Neighborhood Hits	182	Target Neighborhood Hits	613	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.051716 (rank : 466)
Query Neighborhood Hits	182	Target Neighborhood Hits	617	Shared Neighborhood Hits	71
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.057535 (rank : 419)
Query Neighborhood Hits	182	Target Neighborhood Hits	657	Shared Neighborhood Hits	83
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.054526 (rank : 439)
Query Neighborhood Hits	182	Target Neighborhood Hits	680	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.051556 (rank : 468)
Query Neighborhood Hits	182	Target Neighborhood Hits	687	Shared Neighborhood Hits	72
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CFAB_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.054776 (rank : 437)
Query Neighborhood Hits	182	Target Neighborhood Hits	251	Shared Neighborhood Hits	25
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.051828 (rank : 465)
Query Neighborhood Hits	182	Target Neighborhood Hits	262	Shared Neighborhood Hits	25
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFC1_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.052504 (rank : 459)
Query Neighborhood Hits	182	Target Neighborhood Hits	148	Shared Neighborhood Hits	44
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.052729 (rank : 457)
Query Neighborhood Hits	182	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CI094_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.240340 (rank : 101)
Query Neighborhood Hits	182	Target Neighborhood Hits	310	Shared Neighborhood Hits	64
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CILP1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.172842 (rank : 114)
Query Neighborhood Hits	182	Target Neighborhood Hits	266	Shared Neighborhood Hits	68
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.183980 (rank : 110)
Query Neighborhood Hits	182	Target Neighborhood Hits	282	Shared Neighborhood Hits	69
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CO2_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.061347 (rank : 386)
Query Neighborhood Hits	182	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.054196 (rank : 445)
Query Neighborhood Hits	182	Target Neighborhood Hits	250	Shared Neighborhood Hits	25
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

COMP_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.113363 (rank : 195)
Query Neighborhood Hits	182	Target Neighborhood Hits	258	Shared Neighborhood Hits	56
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.117175 (rank : 181)
Query Neighborhood Hits	182	Target Neighborhood Hits	290	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.098126 (rank : 249)
Query Neighborhood Hits	182	Target Neighborhood Hits	441	Shared Neighborhood Hits	62
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.098516 (rank : 246)
Query Neighborhood Hits	182	Target Neighborhood Hits	524	Shared Neighborhood Hits	63
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.077176 (rank : 325)
Query Neighborhood Hits	182	Target Neighborhood Hits	362	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CS1A_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.061636 (rank : 385)
Query Neighborhood Hits	182	Target Neighborhood Hits	360	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.062931 (rank : 378)
Query Neighborhood Hits	182	Target Neighborhood Hits	361	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSPG3_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.071340 (rank : 341)
Query Neighborhood Hits	182	Target Neighborhood Hits	676	Shared Neighborhood Hits	62
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.073598 (rank : 334)
Query Neighborhood Hits	182	Target Neighborhood Hits	657	Shared Neighborhood Hits	61
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CUBN_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.115198 (rank : 187)
Query Neighborhood Hits	182	Target Neighborhood Hits	482	Shared Neighborhood Hits	90
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.122827 (rank : 164)
Query Neighborhood Hits	182	Target Neighborhood Hits	477	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CYR61_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.051514 (rank : 469)
Query Neighborhood Hits	182	Target Neighborhood Hits	159	Shared Neighborhood Hits	51
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

DESC4_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.051152 (rank : 472)
Query Neighborhood Hits	182	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

DLL3_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.125003 (rank : 157)
Query Neighborhood Hits	182	Target Neighborhood Hits	419	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.129513 (rank : 153)
Query Neighborhood Hits	182	Target Neighborhood Hits	399	Shared Neighborhood Hits	78
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EDIL3_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.084139 (rank : 300)
Query Neighborhood Hits	182	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.081083 (rank : 310)
Query Neighborhood Hits	182	Target Neighborhood Hits	317	Shared Neighborhood Hits	61
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.089382 (rank : 278)
Query Neighborhood Hits	182	Target Neighborhood Hits	325	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.079938 (rank : 315)
Query Neighborhood Hits	182	Target Neighborhood Hits	287	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.082224 (rank : 308)
Query Neighborhood Hits	182	Target Neighborhood Hits	270	Shared Neighborhood Hits	59
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.083956 (rank : 302)
Query Neighborhood Hits	182	Target Neighborhood Hits	266	Shared Neighborhood Hits	58
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.107031 (rank : 222)
Query Neighborhood Hits	182	Target Neighborhood Hits	365	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.108063 (rank : 217)
Query Neighborhood Hits	182	Target Neighborhood Hits	379	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.172666 (rank : 115)
Query Neighborhood Hits	182	Target Neighborhood Hits	343	Shared Neighborhood Hits	72
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.171738 (rank : 116)
Query Neighborhood Hits	182	Target Neighborhood Hits	358	Shared Neighborhood Hits	75
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELTD1_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.077279 (rank : 324)
Query Neighborhood Hits	182	Target Neighborhood Hits	269	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.091897 (rank : 273)
Query Neighborhood Hits	182	Target Neighborhood Hits	288	Shared Neighborhood Hits	63
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.106996 (rank : 223)
Query Neighborhood Hits	182	Target Neighborhood Hits	382	Shared Neighborhood Hits	81
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.098474 (rank : 247)
Query Neighborhood Hits	182	Target Neighborhood Hits	349	Shared Neighborhood Hits	76
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.098213 (rank : 248)
Query Neighborhood Hits	182	Target Neighborhood Hits	345	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.059944 (rank : 397)
Query Neighborhood Hits	182	Target Neighborhood Hits	245	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

FA10_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.079613 (rank : 318)
Query Neighborhood Hits	182	Target Neighborhood Hits	431	Shared Neighborhood Hits	79
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.082153 (rank : 309)
Query Neighborhood Hits	182	Target Neighborhood Hits	435	Shared Neighborhood Hits	79
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA12_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.074019 (rank : 332)
Query Neighborhood Hits	182	Target Neighborhood Hits	425	Shared Neighborhood Hits	66
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.077864 (rank : 322)
Query Neighborhood Hits	182	Target Neighborhood Hits	404	Shared Neighborhood Hits	76
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.073027 (rank : 338)
Query Neighborhood Hits	182	Target Neighborhood Hits	374	Shared Neighborhood Hits	68
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FBLN1_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.112251 (rank : 199)
Query Neighborhood Hits	182	Target Neighborhood Hits	324	Shared Neighborhood Hits	71
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.114776 (rank : 189)
Query Neighborhood Hits	182	Target Neighborhood Hits	329	Shared Neighborhood Hits	72
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.110523 (rank : 207)
Query Neighborhood Hits	182	Target Neighborhood Hits	392	Shared Neighborhood Hits	74
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.113604 (rank : 194)
Query Neighborhood Hits	182	Target Neighborhood Hits	505	Shared Neighborhood Hits	79
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.106897 (rank : 225)
Query Neighborhood Hits	182	Target Neighborhood Hits	293	Shared Neighborhood Hits	69
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.103240 (rank : 235)
Query Neighborhood Hits	182	Target Neighborhood Hits	279	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.103564 (rank : 233)
Query Neighborhood Hits	182	Target Neighborhood Hits	278	Shared Neighborhood Hits	69
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.103351 (rank : 234)
Query Neighborhood Hits	182	Target Neighborhood Hits	270	Shared Neighborhood Hits	65
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.106947 (rank : 224)
Query Neighborhood Hits	182	Target Neighborhood Hits	329	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.103010 (rank : 236)
Query Neighborhood Hits	182	Target Neighborhood Hits	317	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.117383 (rank : 179)
Query Neighborhood Hits	182	Target Neighborhood Hits	557	Shared Neighborhood Hits	86
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.117127 (rank : 182)
Query Neighborhood Hits	182	Target Neighborhood Hits	563	Shared Neighborhood Hits	89
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.118296 (rank : 175)
Query Neighborhood Hits	182	Target Neighborhood Hits	560	Shared Neighborhood Hits	90
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.118676 (rank : 174)
Query Neighborhood Hits	182	Target Neighborhood Hits	549	Shared Neighborhood Hits	90
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.116514 (rank : 185)
Query Neighborhood Hits	182	Target Neighborhood Hits	543	Shared Neighborhood Hits	81
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FRAS1_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.085946 (rank : 290)
Query Neighborhood Hits	182	Target Neighborhood Hits	759	Shared Neighborhood Hits	99
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.090769 (rank : 275)
Query Neighborhood Hits	182	Target Neighborhood Hits	747	Shared Neighborhood Hits	96
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.109303 (rank : 213)
Query Neighborhood Hits	182	Target Neighborhood Hits	348	Shared Neighborhood Hits	75
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.110456 (rank : 209)
Query Neighborhood Hits	182	Target Neighborhood Hits	343	Shared Neighborhood Hits	71
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GLU2B_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.102427 (rank : 240)
Query Neighborhood Hits	182	Target Neighborhood Hits	377	Shared Neighborhood Hits	44
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GLU2B_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.094017 (rank : 265)
Query Neighborhood Hits	182	Target Neighborhood Hits	357	Shared Neighborhood Hits	42
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GRN_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.105750 (rank : 226)
Query Neighborhood Hits	182	Target Neighborhood Hits	268	Shared Neighborhood Hits	63
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.088335 (rank : 280)
Query Neighborhood Hits	182	Target Neighborhood Hits	248	Shared Neighborhood Hits	55
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HABP2_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.086574 (rank : 285)
Query Neighborhood Hits	182	Target Neighborhood Hits	431	Shared Neighborhood Hits	76
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HGFA_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.078282 (rank : 321)
Query Neighborhood Hits	182	Target Neighborhood Hits	436	Shared Neighborhood Hits	72
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HHIP_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.056208 (rank : 429)
Query Neighborhood Hits	182	Target Neighborhood Hits	249	Shared Neighborhood Hits	47
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.053718 (rank : 449)
Query Neighborhood Hits	182	Target Neighborhood Hits	219	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

IDD_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.156701 (rank : 122)
Query Neighborhood Hits	182	Target Neighborhood Hits	151	Shared Neighborhood Hits	55
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

ITB1_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.064186 (rank : 369)
Query Neighborhood Hits	182	Target Neighborhood Hits	298	Shared Neighborhood Hits	67
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.051201 (rank : 471)
Query Neighborhood Hits	182	Target Neighborhood Hits	283	Shared Neighborhood Hits	61
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.059502 (rank : 403)
Query Neighborhood Hits	182	Target Neighborhood Hits	325	Shared Neighborhood Hits	68
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.050206 (rank : 481)
Query Neighborhood Hits	182	Target Neighborhood Hits	319	Shared Neighborhood Hits	61
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.054776 (rank : 438)
Query Neighborhood Hits	182	Target Neighborhood Hits	310	Shared Neighborhood Hits	69
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.058261 (rank : 411)
Query Neighborhood Hits	182	Target Neighborhood Hits	329	Shared Neighborhood Hits	70
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.054867 (rank : 436)
Query Neighborhood Hits	182	Target Neighborhood Hits	318	Shared Neighborhood Hits	68
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.057331 (rank : 422)
Query Neighborhood Hits	182	Target Neighborhood Hits	341	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.050174 (rank : 483)
Query Neighborhood Hits	182	Target Neighborhood Hits	290	Shared Neighborhood Hits	60
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.056649 (rank : 425)
Query Neighborhood Hits	182	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

KR101_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.079626 (rank : 317)
Query Neighborhood Hits	182	Target Neighborhood Hits	261	Shared Neighborhood Hits	55
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.088171 (rank : 281)
Query Neighborhood Hits	182	Target Neighborhood Hits	264	Shared Neighborhood Hits	59
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.108236 (rank : 216)
Query Neighborhood Hits	182	Target Neighborhood Hits	313	Shared Neighborhood Hits	68
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.060531 (rank : 393)
Query Neighborhood Hits	182	Target Neighborhood Hits	271	Shared Neighborhood Hits	49
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.114400 (rank : 192)
Query Neighborhood Hits	182	Target Neighborhood Hits	347	Shared Neighborhood Hits	80
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.109652 (rank : 212)
Query Neighborhood Hits	182	Target Neighborhood Hits	330	Shared Neighborhood Hits	70
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.059711 (rank : 400)
Query Neighborhood Hits	182	Target Neighborhood Hits	226	Shared Neighborhood Hits	47
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.073129 (rank : 336)
Query Neighborhood Hits	182	Target Neighborhood Hits	226	Shared Neighborhood Hits	53
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.066769 (rank : 357)
Query Neighborhood Hits	182	Target Neighborhood Hits	269	Shared Neighborhood Hits	55
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.059874 (rank : 398)
Query Neighborhood Hits	182	Target Neighborhood Hits	219	Shared Neighborhood Hits	46
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR412_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.056450 (rank : 428)
Query Neighborhood Hits	182	Target Neighborhood Hits	178	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.054972 (rank : 435)
Query Neighborhood Hits	182	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR511_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.053209 (rank : 452)
Query Neighborhood Hits	182	Target Neighborhood Hits	231	Shared Neighborhood Hits	33
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.052326 (rank : 461)
Query Neighborhood Hits	182	Target Neighborhood Hits	155	Shared Neighborhood Hits	34
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.057890 (rank : 413)
Query Neighborhood Hits	182	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.053691 (rank : 450)
Query Neighborhood Hits	182	Target Neighborhood Hits	126	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA44_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.052997 (rank : 455)
Query Neighborhood Hits	182	Target Neighborhood Hits	162	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA51_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.085294 (rank : 293)
Query Neighborhood Hits	182	Target Neighborhood Hits	288	Shared Neighborhood Hits	63
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.080580 (rank : 311)
Query Neighborhood Hits	182	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA57_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.054436 (rank : 441)
Query Neighborhood Hits	182	Target Neighborhood Hits	269	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.073505 (rank : 335)
Query Neighborhood Hits	182	Target Neighborhood Hits	324	Shared Neighborhood Hits	53
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.069092 (rank : 345)
Query Neighborhood Hits	182	Target Neighborhood Hits	310	Shared Neighborhood Hits	47
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.058859 (rank : 406)
Query Neighborhood Hits	182	Target Neighborhood Hits	198	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.061940 (rank : 383)
Query Neighborhood Hits	182	Target Neighborhood Hits	203	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.057450 (rank : 421)
Query Neighborhood Hits	182	Target Neighborhood Hits	204	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.065584 (rank : 361)
Query Neighborhood Hits	182	Target Neighborhood Hits	185	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.052799 (rank : 456)
Query Neighborhood Hits	182	Target Neighborhood Hits	173	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA1_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.066254 (rank : 358)
Query Neighborhood Hits	182	Target Neighborhood Hits	804	Shared Neighborhood Hits	74
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.072030 (rank : 340)
Query Neighborhood Hits	182	Target Neighborhood Hits	838	Shared Neighborhood Hits	76
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.059579 (rank : 401)
Query Neighborhood Hits	182	Target Neighborhood Hits	1092	Shared Neighborhood Hits	70
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.061209 (rank : 388)
Query Neighborhood Hits	182	Target Neighborhood Hits	1198	Shared Neighborhood Hits	75
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.057520 (rank : 420)
Query Neighborhood Hits	182	Target Neighborhood Hits	859	Shared Neighborhood Hits	77
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA5_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.075830 (rank : 328)
Query Neighborhood Hits	182	Target Neighborhood Hits	976	Shared Neighborhood Hits	82
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.057860 (rank : 415)
Query Neighborhood Hits	182	Target Neighborhood Hits	919	Shared Neighborhood Hits	64
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.064088 (rank : 371)
Query Neighborhood Hits	182	Target Neighborhood Hits	692	Shared Neighborhood Hits	71
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.059871 (rank : 399)
Query Neighborhood Hits	182	Target Neighborhood Hits	722	Shared Neighborhood Hits	67
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.050114 (rank : 484)
Query Neighborhood Hits	182	Target Neighborhood Hits	444	Shared Neighborhood Hits	59
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.059569 (rank : 402)
Query Neighborhood Hits	182	Target Neighborhood Hits	922	Shared Neighborhood Hits	73
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.062782 (rank : 379)
Query Neighborhood Hits	182	Target Neighborhood Hits	856	Shared Neighborhood Hits	73
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.058687 (rank : 407)
Query Neighborhood Hits	182	Target Neighborhood Hits	715	Shared Neighborhood Hits	68
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.051065 (rank : 473)
Query Neighborhood Hits	182	Target Neighborhood Hits	614	Shared Neighborhood Hits	61
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.062372 (rank : 382)
Query Neighborhood Hits	182	Target Neighborhood Hits	588	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.066776 (rank : 356)
Query Neighborhood Hits	182	Target Neighborhood Hits	624	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE3B_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.054168 (rank : 446)
Query Neighborhood Hits	182	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LTB1L_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.119536 (rank : 170)
Query Neighborhood Hits	182	Target Neighborhood Hits	514	Shared Neighborhood Hits	88
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.112892 (rank : 197)
Query Neighborhood Hits	182	Target Neighborhood Hits	479	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.120277 (rank : 168)
Query Neighborhood Hits	182	Target Neighborhood Hits	552	Shared Neighborhood Hits	84
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.111232 (rank : 204)
Query Neighborhood Hits	182	Target Neighborhood Hits	617	Shared Neighborhood Hits	82
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.107941 (rank : 218)
Query Neighborhood Hits	182	Target Neighborhood Hits	502	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.110339 (rank : 210)
Query Neighborhood Hits	182	Target Neighborhood Hits	475	Shared Neighborhood Hits	84
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.117094 (rank : 183)
Query Neighborhood Hits	182	Target Neighborhood Hits	607	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LYAM2_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.059048 (rank : 405)
Query Neighborhood Hits	182	Target Neighborhood Hits	420	Shared Neighborhood Hits	71
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.057084 (rank : 424)
Query Neighborhood Hits	182	Target Neighborhood Hits	378	Shared Neighborhood Hits	61
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.056618 (rank : 426)
Query Neighborhood Hits	182	Target Neighborhood Hits	390	Shared Neighborhood Hits	58
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MASP1_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.066838 (rank : 355)
Query Neighborhood Hits	182	Target Neighborhood Hits	369	Shared Neighborhood Hits	58
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.064506 (rank : 367)
Query Neighborhood Hits	182	Target Neighborhood Hits	364	Shared Neighborhood Hits	58
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.067487 (rank : 351)
Query Neighborhood Hits	182	Target Neighborhood Hits	364	Shared Neighborhood Hits	61
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.067016 (rank : 353)
Query Neighborhood Hits	182	Target Neighborhood Hits	382	Shared Neighborhood Hits	62
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN2_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.095368 (rank : 260)
Query Neighborhood Hits	182	Target Neighborhood Hits	365	Shared Neighborhood Hits	71
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.086358 (rank : 286)
Query Neighborhood Hits	182	Target Neighborhood Hits	356	Shared Neighborhood Hits	65
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.075650 (rank : 329)
Query Neighborhood Hits	182	Target Neighborhood Hits	268	Shared Neighborhood Hits	54
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.079635 (rank : 316)
Query Neighborhood Hits	182	Target Neighborhood Hits	261	Shared Neighborhood Hits	57
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.073929 (rank : 333)
Query Neighborhood Hits	182	Target Neighborhood Hits	287	Shared Neighborhood Hits	60
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.070756 (rank : 343)
Query Neighborhood Hits	182	Target Neighborhood Hits	277	Shared Neighborhood Hits	61
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MEGF6_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.124505 (rank : 158)
Query Neighborhood Hits	182	Target Neighborhood Hits	671	Shared Neighborhood Hits	98
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF8_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.089592 (rank : 277)
Query Neighborhood Hits	182	Target Neighborhood Hits	528	Shared Neighborhood Hits	81
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.085936 (rank : 291)
Query Neighborhood Hits	182	Target Neighborhood Hits	520	Shared Neighborhood Hits	82
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.063003 (rank : 377)
Query Neighborhood Hits	182	Target Neighborhood Hits	557	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.053208 (rank : 453)
Query Neighborhood Hits	182	Target Neighborhood Hits	896	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MFGM_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.057663 (rank : 418)
Query Neighborhood Hits	182	Target Neighborhood Hits	233	Shared Neighborhood Hits	51
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MUC5B_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.054332 (rank : 444)
Query Neighborhood Hits	182	Target Neighborhood Hits	1020	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NAGPA_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.065421 (rank : 362)
Query Neighborhood Hits	182	Target Neighborhood Hits	308	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.113002 (rank : 196)
Query Neighborhood Hits	182	Target Neighborhood Hits	451	Shared Neighborhood Hits	72
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.114653 (rank : 190)
Query Neighborhood Hits	182	Target Neighborhood Hits	449	Shared Neighborhood Hits	77
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.116280 (rank : 186)
Query Neighborhood Hits	182	Target Neighborhood Hits	436	Shared Neighborhood Hits	74
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NETO2_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.085710 (rank : 292)
Query Neighborhood Hits	182	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.086065 (rank : 289)
Query Neighborhood Hits	182	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NFX1_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.063217 (rank : 376)
Query Neighborhood Hits	182	Target Neighborhood Hits	405	Shared Neighborhood Hits	53
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.155600 (rank : 123)
Query Neighborhood Hits	182	Target Neighborhood Hits	329	Shared Neighborhood Hits	67
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.158542 (rank : 120)
Query Neighborhood Hits	182	Target Neighborhood Hits	335	Shared Neighborhood Hits	70
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.148674 (rank : 129)
Query Neighborhood Hits	182	Target Neighborhood Hits	456	Shared Neighborhood Hits	71
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.149327 (rank : 127)
Query Neighborhood Hits	182	Target Neighborhood Hits	338	Shared Neighborhood Hits	71
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NTNG1_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.051668 (rank : 467)
Query Neighborhood Hits	182	Target Neighborhood Hits	247	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.055260 (rank : 431)
Query Neighborhood Hits	182	Target Neighborhood Hits	246	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.058059 (rank : 412)
Query Neighborhood Hits	182	Target Neighborhood Hits	276	Shared Neighborhood Hits	61
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.055667 (rank : 430)
Query Neighborhood Hits	182	Target Neighborhood Hits	276	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PCSK5_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.077563 (rank : 323)
Query Neighborhood Hits	182	Target Neighborhood Hits	613	Shared Neighborhood Hits	93
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

POLS2_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.050731 (rank : 479)
Query Neighborhood Hits	182	Target Neighborhood Hits	192	Shared Neighborhood Hits	21
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PROC_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.074465 (rank : 331)
Query Neighborhood Hits	182	Target Neighborhood Hits	406	Shared Neighborhood Hits	80
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.080219 (rank : 313)
Query Neighborhood Hits	182	Target Neighborhood Hits	426	Shared Neighborhood Hits	81
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROS_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.107866 (rank : 219)
Query Neighborhood Hits	182	Target Neighborhood Hits	340	Shared Neighborhood Hits	74
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.104583 (rank : 228)
Query Neighborhood Hits	182	Target Neighborhood Hits	330	Shared Neighborhood Hits	70
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.102935 (rank : 239)
Query Neighborhood Hits	182	Target Neighborhood Hits	422	Shared Neighborhood Hits	79
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.091617 (rank : 274)
Query Neighborhood Hits	182	Target Neighborhood Hits	410	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RECK_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.059235 (rank : 404)
Query Neighborhood Hits	182	Target Neighborhood Hits	189	Shared Neighborhood Hits	46
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RSPO1_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.058681 (rank : 408)
Query Neighborhood Hits	182	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO1_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.054370 (rank : 442)
Query Neighborhood Hits	182	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

SCUB3_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.118014 (rank : 178)
Query Neighborhood Hits	182	Target Neighborhood Hits	428	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.117347 (rank : 180)
Query Neighborhood Hits	182	Target Neighborhood Hits	442	Shared Neighborhood Hits	82
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SLIT1_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.088895 (rank : 279)
Query Neighborhood Hits	182	Target Neighborhood Hits	700	Shared Neighborhood Hits	82
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.092832 (rank : 269)
Query Neighborhood Hits	182	Target Neighborhood Hits	715	Shared Neighborhood Hits	88
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT3_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.087963 (rank : 282)
Query Neighborhood Hits	182	Target Neighborhood Hits	682	Shared Neighborhood Hits	81
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.082619 (rank : 304)
Query Neighborhood Hits	182	Target Neighborhood Hits	700	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SPIT1_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.153046 (rank : 125)
Query Neighborhood Hits	182	Target Neighborhood Hits	100	Shared Neighborhood Hits	56
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPON2_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.092156 (rank : 272)
Query Neighborhood Hits	182	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SREC2_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.096404 (rank : 257)
Query Neighborhood Hits	182	Target Neighborhood Hits	645	Shared Neighborhood Hits	79
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.094450 (rank : 263)
Query Neighborhood Hits	182	Target Neighborhood Hits	605	Shared Neighborhood Hits	77
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.107623 (rank : 220)
Query Neighborhood Hits	182	Target Neighborhood Hits	645	Shared Neighborhood Hits	91
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.097165 (rank : 253)
Query Neighborhood Hits	182	Target Neighborhood Hits	546	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.096144 (rank : 259)
Query Neighborhood Hits	182	Target Neighborhood Hits	566	Shared Neighborhood Hits	80
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.111960 (rank : 203)
Query Neighborhood Hits	182	Target Neighborhood Hits	528	Shared Neighborhood Hits	90
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SUSD1_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.098113 (rank : 250)
Query Neighborhood Hits	182	Target Neighborhood Hits	285	Shared Neighborhood Hits	61
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.052270 (rank : 462)
Query Neighborhood Hits	182	Target Neighborhood Hits	146	Shared Neighborhood Hits	43
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TENA_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.110514 (rank : 208)
Query Neighborhood Hits	182	Target Neighborhood Hits	631	Shared Neighborhood Hits	90
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENN_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.054064 (rank : 447)
Query Neighborhood Hits	182	Target Neighborhood Hits	484	Shared Neighborhood Hits	70
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.068746 (rank : 348)
Query Neighborhood Hits	182	Target Neighborhood Hits	526	Shared Neighborhood Hits	77
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.070088 (rank : 344)
Query Neighborhood Hits	182	Target Neighborhood Hits	531	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TEST_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.050766 (rank : 478)
Query Neighborhood Hits	182	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

THSD1_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.271097 (rank : 98)
Query Neighborhood Hits	182	Target Neighborhood Hits	136	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

THSD1_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.264769 (rank : 99)
Query Neighborhood Hits	182	Target Neighborhood Hits	153	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TLL1_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.062719 (rank : 380)
Query Neighborhood Hits	182	Target Neighborhood Hits	236	Shared Neighborhood Hits	57
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.063409 (rank : 374)
Query Neighborhood Hits	182	Target Neighborhood Hits	237	Shared Neighborhood Hits	59
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.060933 (rank : 390)
Query Neighborhood Hits	182	Target Neighborhood Hits	241	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.059991 (rank : 396)
Query Neighborhood Hits	182	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TM11D_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.051284 (rank : 470)
Query Neighborhood Hits	182	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.053265 (rank : 451)
Query Neighborhood Hits	182	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.052117 (rank : 463)
Query Neighborhood Hits	182	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS2_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.071047 (rank : 342)
Query Neighborhood Hits	182	Target Neighborhood Hits	252	Shared Neighborhood Hits	54
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS4_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.061271 (rank : 387)
Query Neighborhood Hits	182	Target Neighborhood Hits	203	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.057737 (rank : 417)
Query Neighborhood Hits	182	Target Neighborhood Hits	210	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.050546 (rank : 480)
Query Neighborhood Hits	182	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS5_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.050176 (rank : 482)
Query Neighborhood Hits	182	Target Neighborhood Hits	185	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPSD_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.054338 (rank : 443)
Query Neighborhood Hits	182	Target Neighborhood Hits	333	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TMPSD_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.053029 (rank : 454)
Query Neighborhood Hits	182	Target Neighborhood Hits	334	Shared Neighborhood Hits	27
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TPA_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.063587 (rank : 373)
Query Neighborhood Hits	182	Target Neighborhood Hits	324	Shared Neighborhood Hits	65
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.061861 (rank : 384)
Query Neighborhood Hits	182	Target Neighborhood Hits	335	Shared Neighborhood Hits	62
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRBM_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.108673 (rank : 215)
Query Neighborhood Hits	182	Target Neighborhood Hits	339	Shared Neighborhood Hits	69
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.109250 (rank : 214)
Query Neighborhood Hits	182	Target Neighborhood Hits	361	Shared Neighborhood Hits	70
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP3_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.118051 (rank : 177)
Query Neighborhood Hits	182	Target Neighborhood Hits	250	Shared Neighborhood Hits	58
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.119607 (rank : 169)
Query Neighborhood Hits	182	Target Neighborhood Hits	247	Shared Neighborhood Hits	59
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.123413 (rank : 162)
Query Neighborhood Hits	182	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.122622 (rank : 165)
Query Neighborhood Hits	182	Target Neighborhood Hits	276	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROK_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.054442 (rank : 440)
Query Neighborhood Hits	182	Target Neighborhood Hits	272	Shared Neighborhood Hits	56
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROK_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.053907 (rank : 448)
Query Neighborhood Hits	182	Target Neighborhood Hits	273	Shared Neighborhood Hits	55
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROM_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.097401 (rank : 252)
Query Neighborhood Hits	182	Target Neighborhood Hits	284	Shared Neighborhood Hits	65
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.052053 (rank : 464)
Query Neighborhood Hits	182	Target Neighborhood Hits	600	Shared Neighborhood Hits	67
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.060458 (rank : 395)
Query Neighborhood Hits	182	Target Neighborhood Hits	626	Shared Neighborhood Hits	64
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VWF_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.065215 (rank : 364)
Query Neighborhood Hits	182	Target Neighborhood Hits	396	Shared Neighborhood Hits	72
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.050864 (rank : 476)
Query Neighborhood Hits	182	Target Neighborhood Hits	381	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WIF1_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.104351 (rank : 230)
Query Neighborhood Hits	182	Target Neighborhood Hits	392	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.100469 (rank : 243)
Query Neighborhood Hits	182	Target Neighborhood Hits	393	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WISP1_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.057085 (rank : 423)
Query Neighborhood Hits	182	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP1_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.058453 (rank : 409)
Query Neighborhood Hits	182	Target Neighborhood Hits	123	Shared Neighborhood Hits	43
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP2_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.064133 (rank : 370)
Query Neighborhood Hits	182	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.069020 (rank : 346)
Query Neighborhood Hits	182	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ZAN_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.055089 (rank : 433)
Query Neighborhood Hits	182	Target Neighborhood Hits	679	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZAN_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.121983 (rank : 166)
Query Neighborhood Hits	182	Target Neighborhood Hits	808	Shared Neighborhood Hits	101
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

CO8A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	182	Target Neighborhood Hits	182	Shared Neighborhood Hits	182
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_HUMAN
NC score	0.983998 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	182	Target Neighborhood Hits	200	Shared Neighborhood Hits	159
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_MOUSE
NC score	0.950028 (rank : 3)	θ value	1.76329e-96 (rank : 4)
Query Neighborhood Hits	182	Target Neighborhood Hits	224	Shared Neighborhood Hits	162
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_HUMAN
NC score	0.942575 (rank : 4)	θ value	4.95767e-99 (rank : 3)
Query Neighborhood Hits	182	Target Neighborhood Hits	199	Shared Neighborhood Hits	152
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO6_HUMAN
NC score	0.870011 (rank : 5)	θ value	1.10959e-82 (rank : 5)
Query Neighborhood Hits	182	Target Neighborhood Hits	331	Shared Neighborhood Hits	163
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
NC score	0.842269 (rank : 6)	θ value	7.97034e-73 (rank : 6)
Query Neighborhood Hits	182	Target Neighborhood Hits	278	Shared Neighborhood Hits	156
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO9_MOUSE
NC score	0.832474 (rank : 7)	θ value	2.3998e-69 (rank : 7)
Query Neighborhood Hits	182	Target Neighborhood Hits	153	Shared Neighborhood Hits	108
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CO9_HUMAN
NC score	0.816197 (rank : 8)	θ value	5.7252e-63 (rank : 8)
Query Neighborhood Hits	182	Target Neighborhood Hits	147	Shared Neighborhood Hits	96
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

PROP_MOUSE
NC score	0.499682 (rank : 9)	θ value	4.1701e-05 (rank : 67)
Query Neighborhood Hits	182	Target Neighborhood Hits	165	Shared Neighborhood Hits	77
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROP_HUMAN
NC score	0.492034 (rank : 10)	θ value	0.000121331 (rank : 72)
Query Neighborhood Hits	182	Target Neighborhood Hits	126	Shared Neighborhood Hits	75
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

SSPO_MOUSE
NC score	0.491467 (rank : 11)	θ value	6.87365e-08 (rank : 20)
Query Neighborhood Hits	182	Target Neighborhood Hits	800	Shared Neighborhood Hits	169
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ATS13_HUMAN
NC score	0.464448 (rank : 12)	θ value	2.52405e-10 (rank : 11)
Query Neighborhood Hits	182	Target Neighborhood Hits	238	Shared Neighborhood Hits	71
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
NC score	0.456106 (rank : 13)	θ value	3.64472e-09 (rank : 14)
Query Neighborhood Hits	182	Target Neighborhood Hits	227	Shared Neighborhood Hits	75
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

UNC5A_MOUSE
NC score	0.448411 (rank : 14)	θ value	2.61198e-07 (rank : 26)
Query Neighborhood Hits	182	Target Neighborhood Hits	203	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

ATS8_MOUSE
NC score	0.445789 (rank : 15)	θ value	1.29631e-06 (rank : 37)
Query Neighborhood Hits	182	Target Neighborhood Hits	139	Shared Neighborhood Hits	71
SwissProt Accessions	P57110	Gene names	Adamts8
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2).

PERF_MOUSE
NC score	0.443990 (rank : 16)	θ value	8.38298e-14 (rank : 9)
Query Neighborhood Hits	182	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

UNC5B_MOUSE
NC score	0.439059 (rank : 17)	θ value	2.88788e-06 (rank : 52)
Query Neighborhood Hits	182	Target Neighborhood Hits	226	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

ATS8_HUMAN
NC score	0.437645 (rank : 18)	θ value	2.61198e-07 (rank : 22)
Query Neighborhood Hits	182	Target Neighborhood Hits	145	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

UNC5B_HUMAN
NC score	0.437075 (rank : 19)	θ value	2.88788e-06 (rank : 51)
Query Neighborhood Hits	182	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

ATS9_HUMAN
NC score	0.431666 (rank : 20)	θ value	8.40245e-06 (rank : 56)
Query Neighborhood Hits	182	Target Neighborhood Hits	219	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

UNC5C_HUMAN
NC score	0.431489 (rank : 21)	θ value	1.29631e-06 (rank : 40)
Query Neighborhood Hits	182	Target Neighborhood Hits	226	Shared Neighborhood Hits	71
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
NC score	0.430607 (rank : 22)	θ value	1.29631e-06 (rank : 41)
Query Neighborhood Hits	182	Target Neighborhood Hits	225	Shared Neighborhood Hits	69
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

ATS1_HUMAN
NC score	0.430513 (rank : 23)	θ value	1.29631e-06 (rank : 36)
Query Neighborhood Hits	182	Target Neighborhood Hits	159	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS1_MOUSE
NC score	0.428917 (rank : 24)	θ value	2.21117e-06 (rank : 44)
Query Neighborhood Hits	182	Target Neighborhood Hits	158	Shared Neighborhood Hits	72
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS4_MOUSE
NC score	0.428173 (rank : 25)	θ value	6.87365e-08 (rank : 18)
Query Neighborhood Hits	182	Target Neighborhood Hits	145	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BNJ2, Q8K384	Gene names	Adamts4
Domain Architecture	No domain graphic available
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1).

ATS15_HUMAN
NC score	0.427442 (rank : 26)	θ value	2.88788e-06 (rank : 45)
Query Neighborhood Hits	182	Target Neighborhood Hits	151	Shared Neighborhood Hits	69
SwissProt Accessions	Q8TE58	Gene names	ADAMTS15
Domain Architecture
Description	ADAMTS-15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 15) (ADAM-TS 15) (ADAM-TS15).

ATS4_HUMAN
NC score	0.426562 (rank : 27)	θ value	3.41135e-07 (rank : 27)
Query Neighborhood Hits	182	Target Neighborhood Hits	138	Shared Neighborhood Hits	74
SwissProt Accessions	O75173, Q5VTW2, Q6P4Q8, Q6UWA8, Q9UN83	Gene names	ADAMTS4, KIAA0688
Domain Architecture
Description	ADAMTS-4 precursor (EC 3.4.24.82) (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase-1) (ADMP-1).

ATS20_MOUSE
NC score	0.426413 (rank : 28)	θ value	5.81887e-07 (rank : 31)
Query Neighborhood Hits	182	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS2_HUMAN
NC score	0.425114 (rank : 29)	θ value	0.00020696 (rank : 75)
Query Neighborhood Hits	182	Target Neighborhood Hits	179	Shared Neighborhood Hits	73
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS18_MOUSE
NC score	0.425100 (rank : 30)	θ value	2.44474e-05 (rank : 62)
Query Neighborhood Hits	182	Target Neighborhood Hits	163	Shared Neighborhood Hits	68
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_HUMAN
NC score	0.424067 (rank : 31)	θ value	4.45536e-07 (rank : 29)
Query Neighborhood Hits	182	Target Neighborhood Hits	208	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

TSP2_MOUSE
NC score	0.423650 (rank : 32)	θ value	3.08544e-08 (rank : 15)
Query Neighborhood Hits	182	Target Neighborhood Hits	352	Shared Neighborhood Hits	126
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATS18_HUMAN
NC score	0.423105 (rank : 33)	θ value	2.88788e-06 (rank : 46)
Query Neighborhood Hits	182	Target Neighborhood Hits	169	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS2_MOUSE
NC score	0.421825 (rank : 34)	θ value	0.00035302 (rank : 77)
Query Neighborhood Hits	182	Target Neighborhood Hits	179	Shared Neighborhood Hits	72
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS5_MOUSE
NC score	0.420835 (rank : 35)	θ value	2.88788e-06 (rank : 48)
Query Neighborhood Hits	182	Target Neighborhood Hits	147	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R001	Gene names	Adamts5
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (Implantin).

ATS20_HUMAN
NC score	0.420524 (rank : 36)	θ value	1.99992e-07 (rank : 21)
Query Neighborhood Hits	182	Target Neighborhood Hits	192	Shared Neighborhood Hits	79
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS16_MOUSE
NC score	0.420449 (rank : 37)	θ value	1.69304e-06 (rank : 42)
Query Neighborhood Hits	182	Target Neighborhood Hits	179	Shared Neighborhood Hits	70
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS3_HUMAN
NC score	0.419793 (rank : 38)	θ value	2.88788e-06 (rank : 47)
Query Neighborhood Hits	182	Target Neighborhood Hits	179	Shared Neighborhood Hits	70
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS6_HUMAN
NC score	0.419720 (rank : 39)	θ value	3.19293e-05 (rank : 65)
Query Neighborhood Hits	182	Target Neighborhood Hits	141	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

TSP2_HUMAN
NC score	0.419240 (rank : 40)	θ value	5.26297e-08 (rank : 17)
Query Neighborhood Hits	182	Target Neighborhood Hits	359	Shared Neighborhood Hits	122
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ATS17_HUMAN
NC score	0.417977 (rank : 41)	θ value	4.0297e-08 (rank : 16)
Query Neighborhood Hits	182	Target Neighborhood Hits	194	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

TSP1_HUMAN
NC score	0.417191 (rank : 42)	θ value	2.61198e-07 (rank : 24)
Query Neighborhood Hits	182	Target Neighborhood Hits	389	Shared Neighborhood Hits	129
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

UNC5D_HUMAN
NC score	0.417029 (rank : 43)	θ value	1.09739e-05 (rank : 58)
Query Neighborhood Hits	182	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ATS12_MOUSE
NC score	0.416132 (rank : 44)	θ value	9.92553e-07 (rank : 34)
Query Neighborhood Hits	182	Target Neighborhood Hits	220	Shared Neighborhood Hits	71
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

TSP1_MOUSE
NC score	0.416012 (rank : 45)	θ value	2.61198e-07 (rank : 25)
Query Neighborhood Hits	182	Target Neighborhood Hits	396	Shared Neighborhood Hits	130
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

UNC5D_MOUSE
NC score	0.414643 (rank : 46)	θ value	1.09739e-05 (rank : 59)
Query Neighborhood Hits	182	Target Neighborhood Hits	268	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ATS12_HUMAN
NC score	0.413094 (rank : 47)	θ value	2.21117e-06 (rank : 43)
Query Neighborhood Hits	182	Target Neighborhood Hits	251	Shared Neighborhood Hits	69
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS7_HUMAN
NC score	0.412919 (rank : 48)	θ value	9.29e-05 (rank : 69)
Query Neighborhood Hits	182	Target Neighborhood Hits	169	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS14_HUMAN
NC score	0.412517 (rank : 49)	θ value	7.59969e-07 (rank : 32)
Query Neighborhood Hits	182	Target Neighborhood Hits	382	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS5_HUMAN
NC score	0.408940 (rank : 50)	θ value	7.59969e-07 (rank : 33)
Query Neighborhood Hits	182	Target Neighborhood Hits	141	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UNA0, Q9UKP2	Gene names	ADAMTS5, ADAMTS11, ADMP2
Domain Architecture
Description	ADAMTS-5 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 5) (ADAM-TS 5) (ADAM-TS5) (Aggrecanase-2) (ADMP-2) (ADAM-TS 11).

PERF_HUMAN
NC score	0.406534 (rank : 51)	θ value	2.69671e-12 (rank : 10)
Query Neighborhood Hits	182	Target Neighborhood Hits	48	Shared Neighborhood Hits	19
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

UNC5A_HUMAN
NC score	0.404272 (rank : 52)	θ value	6.43352e-06 (rank : 55)
Query Neighborhood Hits	182	Target Neighborhood Hits	198	Shared Neighborhood Hits	66
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

SPON1_MOUSE
NC score	0.383613 (rank : 53)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	182	Target Neighborhood Hits	123	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

CD320_HUMAN
NC score	0.380884 (rank : 54)	θ value	0.00390308 (rank : 87)
Query Neighborhood Hits	182	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

SPON1_HUMAN
NC score	0.373873 (rank : 55)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	182	Target Neighborhood Hits	117	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

ATL5_HUMAN
NC score	0.363867 (rank : 56)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	182	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATL1_HUMAN
NC score	0.361441 (rank : 57)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	182	Target Neighborhood Hits	93	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL1_MOUSE
NC score	0.357952 (rank : 58)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	182	Target Neighborhood Hits	80	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BLI0	Gene names	Adamtsl1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (Punctin-1).

ATL2_HUMAN
NC score	0.354569 (rank : 59)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	182	Target Neighborhood Hits	125	Shared Neighborhood Hits	69
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
NC score	0.353947 (rank : 60)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	182	Target Neighborhood Hits	137	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

SEM5A_HUMAN
NC score	0.350851 (rank : 61)	θ value	2.13673e-09 (rank : 12)
Query Neighborhood Hits	182	Target Neighborhood Hits	177	Shared Neighborhood Hits	86
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATS19_MOUSE
NC score	0.350427 (rank : 62)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	182	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_HUMAN
NC score	0.349938 (rank : 63)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	182	Target Neighborhood Hits	203	Shared Neighborhood Hits	64
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

SEM5B_MOUSE
NC score	0.345894 (rank : 64)	θ value	3.41135e-07 (rank : 28)
Query Neighborhood Hits	182	Target Neighborhood Hits	190	Shared Neighborhood Hits	82
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5A_MOUSE
NC score	0.345775 (rank : 65)	θ value	2.79066e-09 (rank : 13)
Query Neighborhood Hits	182	Target Neighborhood Hits	162	Shared Neighborhood Hits	70
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

BAI3_MOUSE
NC score	0.345523 (rank : 66)	θ value	0.00665767 (rank : 93)
Query Neighborhood Hits	182	Target Neighborhood Hits	250	Shared Neighborhood Hits	77
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI1_MOUSE
NC score	0.343109 (rank : 67)	θ value	0.000121331 (rank : 71)
Query Neighborhood Hits	182	Target Neighborhood Hits	340	Shared Neighborhood Hits	74
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_HUMAN
NC score	0.343102 (rank : 68)	θ value	0.000121331 (rank : 70)
Query Neighborhood Hits	182	Target Neighborhood Hits	375	Shared Neighborhood Hits	76
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

SEM5B_HUMAN
NC score	0.342734 (rank : 69)	θ value	9.92553e-07 (rank : 35)
Query Neighborhood Hits	182	Target Neighborhood Hits	178	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

BAI3_HUMAN
NC score	0.339977 (rank : 70)	θ value	0.00390308 (rank : 86)
Query Neighborhood Hits	182	Target Neighborhood Hits	246	Shared Neighborhood Hits	73
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

LRP4_HUMAN
NC score	0.337132 (rank : 71)	θ value	4.45536e-07 (rank : 30)
Query Neighborhood Hits	182	Target Neighborhood Hits	355	Shared Neighborhood Hits	114
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
NC score	0.335941 (rank : 72)	θ value	2.61198e-07 (rank : 23)
Query Neighborhood Hits	182	Target Neighborhood Hits	351	Shared Neighborhood Hits	116
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LDLR_MOUSE
NC score	0.334514 (rank : 73)	θ value	3.77169e-06 (rank : 53)
Query Neighborhood Hits	182	Target Neighborhood Hits	382	Shared Neighborhood Hits	111
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

VLDLR_HUMAN
NC score	0.334470 (rank : 74)	θ value	1.09739e-05 (rank : 60)
Query Neighborhood Hits	182	Target Neighborhood Hits	383	Shared Neighborhood Hits	110
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
NC score	0.330652 (rank : 75)	θ value	2.44474e-05 (rank : 64)
Query Neighborhood Hits	182	Target Neighborhood Hits	360	Shared Neighborhood Hits	108
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ATL3_HUMAN
NC score	0.328979 (rank : 76)	θ value	0.62314 (rank : 124)
Query Neighborhood Hits	182	Target Neighborhood Hits	414	Shared Neighborhood Hits	73
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

LDLR_HUMAN
NC score	0.328811 (rank : 77)	θ value	8.40245e-06 (rank : 57)
Query Neighborhood Hits	182	Target Neighborhood Hits	375	Shared Neighborhood Hits	109
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

BAI2_HUMAN
NC score	0.326845 (rank : 78)	θ value	0.000461057 (rank : 79)
Query Neighborhood Hits	182	Target Neighborhood Hits	332	Shared Neighborhood Hits	78
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
NC score	0.326552 (rank : 79)	θ value	0.000461057 (rank : 80)
Query Neighborhood Hits	182	Target Neighborhood Hits	323	Shared Neighborhood Hits	76
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

SORL_MOUSE
NC score	0.325975 (rank : 80)	θ value	2.88788e-06 (rank : 49)
Query Neighborhood Hits	182	Target Neighborhood Hits	439	Shared Neighborhood Hits	104
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SORL_HUMAN
NC score	0.324534 (rank : 81)	θ value	1.29631e-06 (rank : 39)
Query Neighborhood Hits	182	Target Neighborhood Hits	440	Shared Neighborhood Hits	109
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

LRP2_HUMAN
NC score	0.322266 (rank : 82)	θ value	0.000270298 (rank : 76)
Query Neighborhood Hits	182	Target Neighborhood Hits	573	Shared Neighborhood Hits	123
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP8_MOUSE
NC score	0.321926 (rank : 83)	θ value	0.000158464 (rank : 74)
Query Neighborhood Hits	182	Target Neighborhood Hits	385	Shared Neighborhood Hits	112
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_HUMAN
NC score	0.320709 (rank : 84)	θ value	0.00228821 (rank : 83)
Query Neighborhood Hits	182	Target Neighborhood Hits	346	Shared Neighborhood Hits	109
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP1B_HUMAN
NC score	0.316134 (rank : 85)	θ value	2.44474e-05 (rank : 63)
Query Neighborhood Hits	182	Target Neighborhood Hits	602	Shared Neighborhood Hits	123
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
NC score	0.315711 (rank : 86)	θ value	4.92598e-06 (rank : 54)
Query Neighborhood Hits	182	Target Neighborhood Hits	606	Shared Neighborhood Hits	124
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
NC score	0.315332 (rank : 87)	θ value	1.29631e-06 (rank : 38)
Query Neighborhood Hits	182	Target Neighborhood Hits	617	Shared Neighborhood Hits	124
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP6_HUMAN
NC score	0.314925 (rank : 88)	θ value	0.00509761 (rank : 90)
Query Neighborhood Hits	182	Target Neighborhood Hits	235	Shared Neighborhood Hits	85
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
NC score	0.314748 (rank : 89)	θ value	0.00509761 (rank : 91)
Query Neighborhood Hits	182	Target Neighborhood Hits	232	Shared Neighborhood Hits	83
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP10_HUMAN
NC score	0.311437 (rank : 90)	θ value	0.00665767 (rank : 94)
Query Neighborhood Hits	182	Target Neighborhood Hits	197	Shared Neighborhood Hits	78
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP5_HUMAN
NC score	0.309043 (rank : 91)	θ value	0.00298849 (rank : 85)
Query Neighborhood Hits	182	Target Neighborhood Hits	224	Shared Neighborhood Hits	80
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP10_MOUSE
NC score	0.307453 (rank : 92)	θ value	0.00869519 (rank : 95)
Query Neighborhood Hits	182	Target Neighborhood Hits	169	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP5_MOUSE
NC score	0.307003 (rank : 93)	θ value	0.0431538 (rank : 102)
Query Neighborhood Hits	182	Target Neighborhood Hits	236	Shared Neighborhood Hits	84
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP3_HUMAN
NC score	0.303504 (rank : 94)	θ value	0.00390308 (rank : 88)
Query Neighborhood Hits	182	Target Neighborhood Hits	280	Shared Neighborhood Hits	84
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP12_MOUSE
NC score	0.284697 (rank : 95)	θ value	0.0113563 (rank : 96)
Query Neighborhood Hits	182	Target Neighborhood Hits	180	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.282840 (rank : 96)	θ value	0.0148317 (rank : 98)
Query Neighborhood Hits	182	Target Neighborhood Hits	205	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

HMCN1_HUMAN
NC score	0.276034 (rank : 97)	θ value	6.87365e-08 (rank : 19)
Query Neighborhood Hits	182	Target Neighborhood Hits	983	Shared Neighborhood Hits	132
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

THSD1_HUMAN
NC score	0.271097 (rank : 98)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	182	Target Neighborhood Hits	136	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

THSD1_MOUSE
NC score	0.264769 (rank : 99)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	182	Target Neighborhood Hits	153	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

CILP2_HUMAN
NC score	0.258794 (rank : 100)	θ value	0.0330416 (rank : 100)
Query Neighborhood Hits	182	Target Neighborhood Hits	307	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CI094_HUMAN
NC score	0.240340 (rank : 101)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	182	Target Neighborhood Hits	310	Shared Neighborhood Hits	64
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CR001_HUMAN
NC score	0.226259 (rank : 102)	θ value	0.62314 (rank : 125)
Query Neighborhood Hits	182	Target Neighborhood Hits	68	Shared Neighborhood Hits	52
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
NC score	0.224233 (rank : 103)	θ value	0.62314 (rank : 126)
Query Neighborhood Hits	182	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

LRP11_MOUSE
NC score	0.219257 (rank : 104)	θ value	1.81305 (rank : 144)
Query Neighborhood Hits	182	Target Neighborhood Hits	81	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

CORIN_HUMAN
NC score	0.210007 (rank : 105)	θ value	3.19293e-05 (rank : 66)
Query Neighborhood Hits	182	Target Neighborhood Hits	453	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

ST14_HUMAN
NC score	0.206615 (rank : 106)	θ value	2.88788e-06 (rank : 50)
Query Neighborhood Hits	182	Target Neighborhood Hits	409	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

CORIN_MOUSE
NC score	0.205487 (rank : 107)	θ value	0.000158464 (rank : 73)
Query Neighborhood Hits	182	Target Neighborhood Hits	451	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ST14_MOUSE
NC score	0.201079 (rank : 108)	θ value	5.44631e-05 (rank : 68)
Query Neighborhood Hits	182	Target Neighborhood Hits	419	Shared Neighborhood Hits	101
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

LRP11_HUMAN
NC score	0.193548 (rank : 109)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	182	Target Neighborhood Hits	82	Shared Neighborhood Hits	58
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

CILP1_MOUSE
NC score	0.183980 (rank : 110)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	182	Target Neighborhood Hits	282	Shared Neighborhood Hits	69
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

IDD_HUMAN
NC score	0.183188 (rank : 111)	θ value	4.03905 (rank : 158)
Query Neighborhood Hits	182	Target Neighborhood Hits	127	Shared Neighborhood Hits	60
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

PGBM_MOUSE
NC score	0.176188 (rank : 112)	θ value	0.000786445 (rank : 82)
Query Neighborhood Hits	182	Target Neighborhood Hits	1073	Shared Neighborhood Hits	122
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_HUMAN
NC score	0.174643 (rank : 113)	θ value	0.000602161 (rank : 81)
Query Neighborhood Hits	182	Target Neighborhood Hits	1113	Shared Neighborhood Hits	126
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CILP1_HUMAN
NC score	0.172842 (rank : 114)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	182	Target Neighborhood Hits	266	Shared Neighborhood Hits	68
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

EGF_HUMAN
NC score	0.172666 (rank : 115)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	182	Target Neighborhood Hits	343	Shared Neighborhood Hits	72
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
NC score	0.171738 (rank : 116)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	182	Target Neighborhood Hits	358	Shared Neighborhood Hits	75
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

TMPS7_MOUSE
NC score	0.160433 (rank : 117)	θ value	0.00228821 (rank : 84)
Query Neighborhood Hits	182	Target Neighborhood Hits	275	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

CFAI_HUMAN
NC score	0.160002 (rank : 118)	θ value	0.00509761 (rank : 89)
Query Neighborhood Hits	182	Target Neighborhood Hits	289	Shared Neighborhood Hits	77
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TMPS6_HUMAN
NC score	0.158787 (rank : 119)	θ value	1.43324e-05 (rank : 61)
Query Neighborhood Hits	182	Target Neighborhood Hits	338	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

NID1_MOUSE
NC score	0.158542 (rank : 120)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	182	Target Neighborhood Hits	335	Shared Neighborhood Hits	70
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TMPS7_HUMAN
NC score	0.157841 (rank : 121)	θ value	0.0148317 (rank : 99)
Query Neighborhood Hits	182	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

IDD_MOUSE
NC score	0.156701 (rank : 122)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	182	Target Neighborhood Hits	151	Shared Neighborhood Hits	55
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

NID1_HUMAN
NC score	0.155600 (rank : 123)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	182	Target Neighborhood Hits	329	Shared Neighborhood Hits	67
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

MFRP_MOUSE
NC score	0.153151 (rank : 124)	θ value	0.0431538 (rank : 103)
Query Neighborhood Hits	182	Target Neighborhood Hits	166	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

SPIT1_HUMAN
NC score	0.153046 (rank : 125)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	182	Target Neighborhood Hits	100	Shared Neighborhood Hits	56
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

CFAI_MOUSE
NC score	0.150457 (rank : 126)	θ value	0.0148317 (rank : 97)
Query Neighborhood Hits	182	Target Neighborhood Hits	290	Shared Neighborhood Hits	75
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

NID2_MOUSE
NC score	0.149327 (rank : 127)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	182	Target Neighborhood Hits	338	Shared Neighborhood Hits	71
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

TMPS6_MOUSE
NC score	0.148834 (rank : 128)	θ value	0.00035302 (rank : 78)
Query Neighborhood Hits	182	Target Neighborhood Hits	341	Shared Neighborhood Hits	84
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

NID2_HUMAN
NC score	0.148674 (rank : 129)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	182	Target Neighborhood Hits	456	Shared Neighborhood Hits	71
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

SPIT1_MOUSE
NC score	0.145834 (rank : 130)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	182	Target Neighborhood Hits	96	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

DLL1_HUMAN
NC score	0.145074 (rank : 131)	θ value	1.06291 (rank : 136)
Query Neighborhood Hits	182	Target Neighborhood Hits	455	Shared Neighborhood Hits	93
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

NOTC1_MOUSE
NC score	0.145070 (rank : 132)	θ value	0.0330416 (rank : 101)
Query Neighborhood Hits	182	Target Neighborhood Hits	916	Shared Neighborhood Hits	92
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

MFRP_HUMAN
NC score	0.144554 (rank : 133)	θ value	1.38821 (rank : 139)
Query Neighborhood Hits	182	Target Neighborhood Hits	165	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

JAG2_MOUSE
NC score	0.144235 (rank : 134)	θ value	0.813845 (rank : 130)
Query Neighborhood Hits	182	Target Neighborhood Hits	504	Shared Neighborhood Hits	90
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

JAG1_HUMAN
NC score	0.144017 (rank : 135)	θ value	0.125558 (rank : 110)
Query Neighborhood Hits	182	Target Neighborhood Hits	514	Shared Neighborhood Hits	83
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.142888 (rank : 136)	θ value	0.0961366 (rank : 106)
Query Neighborhood Hits	182	Target Neighborhood Hits	518	Shared Neighborhood Hits	81
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
NC score	0.142485 (rank : 137)	θ value	1.81305 (rank : 143)
Query Neighborhood Hits	182	Target Neighborhood Hits	491	Shared Neighborhood Hits	84
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NOTC2_MOUSE
NC score	0.142189 (rank : 138)	θ value	0.47712 (rank : 120)
Query Neighborhood Hits	182	Target Neighborhood Hits	1069	Shared Neighborhood Hits	97
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DLL1_MOUSE
NC score	0.141944 (rank : 139)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	182	Target Neighborhood Hits	456	Shared Neighborhood Hits	90
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

NOTC1_HUMAN
NC score	0.141362 (rank : 140)	θ value	0.00509761 (rank : 92)
Query Neighborhood Hits	182	Target Neighborhood Hits	906	Shared Neighborhood Hits	93
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DLL4_HUMAN
NC score	0.141336 (rank : 141)	θ value	0.62314 (rank : 127)
Query Neighborhood Hits	182	Target Neighborhood Hits	435	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC2_HUMAN
NC score	0.140704 (rank : 142)	θ value	0.47712 (rank : 119)
Query Neighborhood Hits	182	Target Neighborhood Hits	1113	Shared Neighborhood Hits	96
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DLL4_MOUSE
NC score	0.135975 (rank : 143)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	182	Target Neighborhood Hits	440	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

CRUM1_HUMAN
NC score	0.135544 (rank : 144)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	182	Target Neighborhood Hits	457	Shared Neighborhood Hits	86
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DNER_HUMAN
NC score	0.135534 (rank : 145)	θ value	0.0961366 (rank : 105)
Query Neighborhood Hits	182	Target Neighborhood Hits	460	Shared Neighborhood Hits	74
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

ADAM8_HUMAN
NC score	0.135494 (rank : 146)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	182	Target Neighborhood Hits	327	Shared Neighborhood Hits	81
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

NOTC3_MOUSE
NC score	0.133500 (rank : 147)	θ value	0.47712 (rank : 122)
Query Neighborhood Hits	182	Target Neighborhood Hits	975	Shared Neighborhood Hits	108
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ADAM8_MOUSE
NC score	0.132788 (rank : 148)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	182	Target Neighborhood Hits	326	Shared Neighborhood Hits	88
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

NOTC4_HUMAN
NC score	0.132658 (rank : 149)	θ value	0.125558 (rank : 111)
Query Neighborhood Hits	182	Target Neighborhood Hits	905	Shared Neighborhood Hits	91
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC3_HUMAN
NC score	0.132542 (rank : 150)	θ value	0.47712 (rank : 121)
Query Neighborhood Hits	182	Target Neighborhood Hits	1062	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CRUM1_MOUSE
NC score	0.131715 (rank : 151)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	182	Target Neighborhood Hits	444	Shared Neighborhood Hits	85
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DNER_MOUSE
NC score	0.129937 (rank : 152)	θ value	0.125558 (rank : 108)
Query Neighborhood Hits	182	Target Neighborhood Hits	413	Shared Neighborhood Hits	76
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DLL3_MOUSE
NC score	0.129513 (rank : 153)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	182	Target Neighborhood Hits	399	Shared Neighborhood Hits	78
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

CRUM2_HUMAN
NC score	0.129050 (rank : 154)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	182	Target Neighborhood Hits	453	Shared Neighborhood Hits	77
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

ADA19_MOUSE
NC score	0.128776 (rank : 155)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	182	Target Neighborhood Hits	315	Shared Neighborhood Hits	87
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

DLK_HUMAN
NC score	0.127394 (rank : 156)	θ value	0.47712 (rank : 117)
Query Neighborhood Hits	182	Target Neighborhood Hits	401	Shared Neighborhood Hits	75
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL3_HUMAN
NC score	0.125003 (rank : 157)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	182	Target Neighborhood Hits	419	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

MEGF6_HUMAN
NC score	0.124505 (rank : 158)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	182	Target Neighborhood Hits	671	Shared Neighborhood Hits	98
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

ADA28_MOUSE
NC score	0.124293 (rank : 159)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	182	Target Neighborhood Hits	241	Shared Neighborhood Hits	70
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

NOTC4_MOUSE
NC score	0.123699 (rank : 160)	θ value	0.21417 (rank : 113)
Query Neighborhood Hits	182	Target Neighborhood Hits	872	Shared Neighborhood Hits	90
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ADA19_HUMAN
NC score	0.123606 (rank : 161)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	182	Target Neighborhood Hits	381	Shared Neighborhood Hits	80
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

TSP4_HUMAN
NC score	0.123413 (rank : 162)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	182	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

LTB1L_HUMAN
NC score	0.123135 (rank : 163)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	182	Target Neighborhood Hits	553	Shared Neighborhood Hits	88
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CUBN_MOUSE
NC score	0.122827 (rank : 164)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	182	Target Neighborhood Hits	477	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

TSP4_MOUSE
NC score	0.122622 (rank : 165)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	182	Target Neighborhood Hits	276	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

ZAN_MOUSE
NC score	0.121983 (rank : 166)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	182	Target Neighborhood Hits	808	Shared Neighborhood Hits	101
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ADA28_HUMAN
NC score	0.121536 (rank : 167)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	182	Target Neighborhood Hits	244	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

LTBP2_HUMAN
NC score	0.120277 (rank : 168)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	182	Target Neighborhood Hits	552	Shared Neighborhood Hits	84
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TSP3_MOUSE
NC score	0.119607 (rank : 169)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	182	Target Neighborhood Hits	247	Shared Neighborhood Hits	59
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

LTB1L_MOUSE
NC score	0.119536 (rank : 170)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	182	Target Neighborhood Hits	514	Shared Neighborhood Hits	88
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ADAM7_HUMAN
NC score	0.119026 (rank : 171)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	182	Target Neighborhood Hits	221	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

TENX_HUMAN
NC score	0.118985 (rank : 172)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	182	Target Neighborhood Hits	789	Shared Neighborhood Hits	100
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

DLK_MOUSE
NC score	0.118727 (rank : 173)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	182	Target Neighborhood Hits	374	Shared Neighborhood Hits	75
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

FBN2_MOUSE
NC score	0.118676 (rank : 174)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	182	Target Neighborhood Hits	549	Shared Neighborhood Hits	90
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
NC score	0.118296 (rank : 175)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	182	Target Neighborhood Hits	560	Shared Neighborhood Hits	90
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

ADAM9_MOUSE
NC score	0.118278 (rank : 176)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	182	Target Neighborhood Hits	325	Shared Neighborhood Hits	78
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

TSP3_HUMAN
NC score	0.118051 (rank : 177)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	182	Target Neighborhood Hits	250	Shared Neighborhood Hits	58
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

SCUB3_HUMAN
NC score	0.118014 (rank : 178)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	182	Target Neighborhood Hits	428	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

FBN1_HUMAN
NC score	0.117383 (rank : 179)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	182	Target Neighborhood Hits	557	Shared Neighborhood Hits	86
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

SCUB3_MOUSE
NC score	0.117347 (rank : 180)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	182	Target Neighborhood Hits	442	Shared Neighborhood Hits	82
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

COMP_MOUSE
NC score	0.117175 (rank : 181)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	182	Target Neighborhood Hits	290	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

FBN1_MOUSE
NC score	0.117127 (rank : 182)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	182	Target Neighborhood Hits	563	Shared Neighborhood Hits	89
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP4_MOUSE
NC score	0.117094 (rank : 183)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	182	Target Neighborhood Hits	607	Shared Neighborhood Hits	86
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTB1S_HUMAN
NC score	0.116548 (rank : 184)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	182	Target Neighborhood Hits	502	Shared Neighborhood Hits	84
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBN3_HUMAN
NC score	0.116514 (rank : 185)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	182	Target Neighborhood Hits	543	Shared Neighborhood Hits	81
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

NELL2_MOUSE
NC score	0.116280 (rank : 186)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	182	Target Neighborhood Hits	436	Shared Neighborhood Hits	74
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

CUBN_HUMAN
NC score	0.115198 (rank : 187)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	182	Target Neighborhood Hits	482	Shared Neighborhood Hits	90
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

ADA12_HUMAN
NC score	0.115097 (rank : 188)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	182	Target Neighborhood Hits	224	Shared Neighborhood Hits	66
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

FBLN1_MOUSE
NC score	0.114776 (rank : 189)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	182	Target Neighborhood Hits	329	Shared Neighborhood Hits	72
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

NELL2_HUMAN
NC score	0.114653 (rank : 190)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	182	Target Neighborhood Hits	449	Shared Neighborhood Hits	77
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

ADA33_HUMAN
NC score	0.114416 (rank : 191)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	182	Target Neighborhood Hits	264	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

KR106_HUMAN
NC score	0.114400 (rank : 192)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	182	Target Neighborhood Hits	347	Shared Neighborhood Hits	80
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

ADA15_HUMAN
NC score	0.114263 (rank : 193)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	182	Target Neighborhood Hits	288	Shared Neighborhood Hits	76
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

FBLN2_MOUSE
NC score	0.113604 (rank : 194)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	182	Target Neighborhood Hits	505	Shared Neighborhood Hits	79
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

COMP_HUMAN
NC score	0.113363 (rank : 195)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	182	Target Neighborhood Hits	258	Shared Neighborhood Hits	56
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NELL1_HUMAN
NC score	0.113002 (rank : 196)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	182	Target Neighborhood Hits	451	Shared Neighborhood Hits	72
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

LTB1S_MOUSE
NC score	0.112892 (rank : 197)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	182	Target Neighborhood Hits	479	Shared Neighborhood Hits	84
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

C1QR1_HUMAN
NC score	0.112292 (rank : 198)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	182	Target Neighborhood Hits	493	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

FBLN1_HUMAN
NC score	0.112251 (rank : 199)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	182	Target Neighborhood Hits	324	Shared Neighborhood Hits	71
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

ADAM7_MOUSE
NC score	0.112247 (rank : 200)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	182	Target Neighborhood Hits	200	Shared Neighborhood Hits	67
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADAM9_HUMAN
NC score	0.112197 (rank : 201)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	182	Target Neighborhood Hits	243	Shared Neighborhood Hits	75
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ENTK_HUMAN
NC score	0.112106 (rank : 202)	θ value	0.125558 (rank : 109)
Query Neighborhood Hits	182	Target Neighborhood Hits	310	Shared Neighborhood Hits	66
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

STAB2_MOUSE
NC score	0.111960 (rank : 203)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	182	Target Neighborhood Hits	528	Shared Neighborhood Hits	90
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

LTBP2_MOUSE
NC score	0.111232 (rank : 204)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	182	Target Neighborhood Hits	617	Shared Neighborhood Hits	82
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

C1QR1_MOUSE
NC score	0.111086 (rank : 205)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	182	Target Neighborhood Hits	342	Shared Neighborhood Hits	68
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

TENA_MOUSE
NC score	0.110573 (rank : 206)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	182	Target Neighborhood Hits	596	Shared Neighborhood Hits	90
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

FBLN2_HUMAN
NC score	0.110523 (rank : 207)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	182	Target Neighborhood Hits	392	Shared Neighborhood Hits	74
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

TENA_HUMAN
NC score	0.110514 (rank : 208)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	182	Target Neighborhood Hits	631	Shared Neighborhood Hits	90
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

GAS6_MOUSE
NC score	0.110456 (rank : 209)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	182	Target Neighborhood Hits	343	Shared Neighborhood Hits	71
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

LTBP3_MOUSE
NC score	0.110339 (rank : 210)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	182	Target Neighborhood Hits	475	Shared Neighborhood Hits	84
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

ADA12_MOUSE
NC score	0.109691 (rank : 211)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	182	Target Neighborhood Hits	474	Shared Neighborhood Hits	67
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

KR107_HUMAN
NC score	0.109652 (rank : 212)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	182	Target Neighborhood Hits	330	Shared Neighborhood Hits	70
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

GAS6_HUMAN
NC score	0.109303 (rank : 213)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	182	Target Neighborhood Hits	348	Shared Neighborhood Hits	75
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

TRBM_MOUSE
NC score	0.109250 (rank : 214)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	182	Target Neighborhood Hits	361	Shared Neighborhood Hits	70
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_HUMAN
NC score	0.108673 (rank : 215)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	182	Target Neighborhood Hits	339	Shared Neighborhood Hits	69
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

KR104_HUMAN
NC score	0.108236 (rank : 216)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	182	Target Neighborhood Hits	313	Shared Neighborhood Hits	68
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

EGFL9_MOUSE
NC score	0.108063 (rank : 217)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	182	Target Neighborhood Hits	379	Shared Neighborhood Hits	73
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

LTBP3_HUMAN
NC score	0.107941 (rank : 218)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	182	Target Neighborhood Hits	502	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

PROS_HUMAN
NC score	0.107866 (rank : 219)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	182	Target Neighborhood Hits	340	Shared Neighborhood Hits	74
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SREC_HUMAN
NC score	0.107623 (rank : 220)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	182	Target Neighborhood Hits	645	Shared Neighborhood Hits	91
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ADM1B_MOUSE
NC score	0.107132 (rank : 221)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	182	Target Neighborhood Hits	236	Shared Neighborhood Hits	80
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

EGFL9_HUMAN
NC score	0.107031 (rank : 222)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	182	Target Neighborhood Hits	365	Shared Neighborhood Hits	72
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EMR1_HUMAN
NC score	0.106996 (rank : 223)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	182	Target Neighborhood Hits	382	Shared Neighborhood Hits	81
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

FBLN5_HUMAN
NC score	0.106947 (rank : 224)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	182	Target Neighborhood Hits	329	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN3_HUMAN
NC score	0.106897 (rank : 225)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	182	Target Neighborhood Hits	293	Shared Neighborhood Hits	69
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

GRN_HUMAN
NC score	0.105750 (rank : 226)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	182	Target Neighborhood Hits	268	Shared Neighborhood Hits	63
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

ENTK_MOUSE
NC score	0.105323 (rank : 227)	θ value	0.62314 (rank : 128)
Query Neighborhood Hits	182	Target Neighborhood Hits	338	Shared Neighborhood Hits	68
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

PROS_MOUSE
NC score	0.104583 (rank : 228)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	182	Target Neighborhood Hits	330	Shared Neighborhood Hits	70
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

NETO1_HUMAN
NC score	0.104396 (rank : 229)	θ value	1.81305 (rank : 145)
Query Neighborhood Hits	182	Target Neighborhood Hits	110	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

WIF1_HUMAN
NC score	0.104351 (rank : 230)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	182	Target Neighborhood Hits	392	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

NETO1_MOUSE
NC score	0.104186 (rank : 231)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	182	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

ADA33_MOUSE
NC score	0.103956 (rank : 232)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	182	Target Neighborhood Hits	231	Shared Neighborhood Hits	65
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

FBLN4_HUMAN
NC score	0.103564 (rank : 233)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	182	Target Neighborhood Hits	278	Shared Neighborhood Hits	69
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
NC score	0.103351 (rank : 234)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	182	Target Neighborhood Hits	270	Shared Neighborhood Hits	65
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN3_MOUSE
NC score	0.103240 (rank : 235)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	182	Target Neighborhood Hits	279	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN5_MOUSE
NC score	0.103010 (rank : 236)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	182	Target Neighborhood Hits	317	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

STAB2_HUMAN
NC score	0.103004 (rank : 237)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	182	Target Neighborhood Hits	534	Shared Neighborhood Hits	83
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

ADA15_MOUSE
NC score	0.102950 (rank : 238)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	182	Target Neighborhood Hits	324	Shared Neighborhood Hits	80
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

PROZ_HUMAN
NC score	0.102935 (rank : 239)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	182	Target Neighborhood Hits	422	Shared Neighborhood Hits	79
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

GLU2B_HUMAN
NC score	0.102427 (rank : 240)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	182	Target Neighborhood Hits	377	Shared Neighborhood Hits	44
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

UROM_MOUSE
NC score	0.100803 (rank : 241)	θ value	0.62314 (rank : 129)
Query Neighborhood Hits	182	Target Neighborhood Hits	276	Shared Neighborhood Hits	66
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ADM1A_MOUSE
NC score	0.100518 (rank : 242)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	182	Target Neighborhood Hits	230	Shared Neighborhood Hits	71
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

WIF1_MOUSE
NC score	0.100469 (rank : 243)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	182	Target Neighborhood Hits	393	Shared Neighborhood Hits	64
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ADEC1_HUMAN
NC score	0.099774 (rank : 244)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	182	Target Neighborhood Hits	80	Shared Neighborhood Hits	26
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

CD97_HUMAN
NC score	0.099437 (rank : 245)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	182	Target Neighborhood Hits	353	Shared Neighborhood Hits	72
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CREL1_MOUSE
NC score	0.098516 (rank : 246)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	182	Target Neighborhood Hits	524	Shared Neighborhood Hits	63
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EMR1_MOUSE
NC score	0.098474 (rank : 247)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	182	Target Neighborhood Hits	349	Shared Neighborhood Hits	76
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
NC score	0.098213 (rank : 248)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	182	Target Neighborhood Hits	345	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

CREL1_HUMAN
NC score	0.098126 (rank : 249)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	182	Target Neighborhood Hits	441	Shared Neighborhood Hits	62
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

SUSD1_HUMAN
NC score	0.098113 (rank : 250)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	182	Target Neighborhood Hits	285	Shared Neighborhood Hits	61
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TMPS9_HUMAN
NC score	0.097602 (rank : 251)	θ value	0.279714 (rank : 115)
Query Neighborhood Hits	182	Target Neighborhood Hits	276	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

UROM_HUMAN
NC score	0.097401 (rank : 252)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	182	Target Neighborhood Hits	284	Shared Neighborhood Hits	65
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

STAB1_HUMAN
NC score	0.097165 (rank : 253)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	182	Target Neighborhood Hits	546	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

HABP2_MOUSE
NC score	0.097103 (rank : 254)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	182	Target Neighborhood Hits	445	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

AGRIN_HUMAN
NC score	0.096976 (rank : 255)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	182	Target Neighborhood Hits	582	Shared Neighborhood Hits	84
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ADA23_MOUSE
NC score	0.096441 (rank : 256)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	182	Target Neighborhood Hits	245	Shared Neighborhood Hits	83
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

SREC2_HUMAN
NC score	0.096404 (rank : 257)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	182	Target Neighborhood Hits	645	Shared Neighborhood Hits	79
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ADA24_MOUSE
NC score	0.096168 (rank : 258)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	182	Target Neighborhood Hits	230	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

STAB1_MOUSE
NC score	0.096144 (rank : 259)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	182	Target Neighborhood Hits	566	Shared Neighborhood Hits	80
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

MATN2_HUMAN
NC score	0.095368 (rank : 260)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	182	Target Neighborhood Hits	365	Shared Neighborhood Hits	71
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

SPON2_MOUSE
NC score	0.094503 (rank : 261)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	182	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

ADA22_HUMAN
NC score	0.094483 (rank : 262)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	182	Target Neighborhood Hits	211	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

SREC2_MOUSE
NC score	0.094450 (rank : 263)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	182	Target Neighborhood Hits	605	Shared Neighborhood Hits	77
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TMPS9_MOUSE
NC score	0.094368 (rank : 264)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	182	Target Neighborhood Hits	296	Shared Neighborhood Hits	61
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

GLU2B_MOUSE
NC score	0.094017 (rank : 265)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	182	Target Neighborhood Hits	357	Shared Neighborhood Hits	42
SwissProt Accessions	O08795, Q921X2	Gene names	Prkcsh
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

ADA23_HUMAN
NC score	0.093982 (rank : 266)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	182	Target Neighborhood Hits	235	Shared Neighborhood Hits	78
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA22_MOUSE
NC score	0.093454 (rank : 267)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	182	Target Neighborhood Hits	225	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

RXFP2_HUMAN
NC score	0.093065 (rank : 268)	θ value	0.0736092 (rank : 104)
Query Neighborhood Hits	182	Target Neighborhood Hits	736	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WXD0	Gene names	RXFP2, GPR106, GREAT, LGR8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

SLIT1_MOUSE
NC score	0.092832 (rank : 269)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	182	Target Neighborhood Hits	715	Shared Neighborhood Hits	88
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ADA21_MOUSE
NC score	0.092760 (rank : 270)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	182	Target Neighborhood Hits	172	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA11_MOUSE
NC score	0.092315 (rank : 271)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	182	Target Neighborhood Hits	263	Shared Neighborhood Hits	72
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

SPON2_HUMAN
NC score	0.092156 (rank : 272)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	182	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

ELTD1_MOUSE
NC score	0.091897 (rank : 273)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	182	Target Neighborhood Hits	288	Shared Neighborhood Hits	63
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

PROZ_MOUSE
NC score	0.091617 (rank : 274)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	182	Target Neighborhood Hits	410	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FRAS1_MOUSE
NC score	0.090769 (rank : 275)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	182	Target Neighborhood Hits	747	Shared Neighborhood Hits	96
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SLIT2_HUMAN
NC score	0.089739 (rank : 276)	θ value	1.06291 (rank : 138)
Query Neighborhood Hits	182	Target Neighborhood Hits	708	Shared Neighborhood Hits	83
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

MEGF8_HUMAN
NC score	0.089592 (rank : 277)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	182	Target Neighborhood Hits	528	Shared Neighborhood Hits	81
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

EGFL7_HUMAN
NC score	0.089382 (rank : 278)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	182	Target Neighborhood Hits	325	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

SLIT1_HUMAN
NC score	0.088895 (rank : 279)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	182	Target Neighborhood Hits	700	Shared Neighborhood Hits	82
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

GRN_MOUSE
NC score	0.088335 (rank : 280)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	182	Target Neighborhood Hits	248	Shared Neighborhood Hits	55
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KR102_HUMAN
NC score	0.088171 (rank : 281)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	182	Target Neighborhood Hits	264	Shared Neighborhood Hits	59
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

SLIT3_HUMAN
NC score	0.087963 (rank : 282)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	182	Target Neighborhood Hits	682	Shared Neighborhood Hits	81
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

CD248_MOUSE
NC score	0.087704 (rank : 283)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	182	Target Neighborhood Hits	578	Shared Neighborhood Hits	62
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TMPS3_HUMAN
NC score	0.087304 (rank : 284)	θ value	0.0961366 (rank : 107)
Query Neighborhood Hits	182	Target Neighborhood Hits	245	Shared Neighborhood Hits	63
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

HABP2_HUMAN
NC score	0.086574 (rank : 285)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	182	Target Neighborhood Hits	431	Shared Neighborhood Hits	76
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

MATN2_MOUSE
NC score	0.086358 (rank : 286)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	182	Target Neighborhood Hits	356	Shared Neighborhood Hits	65
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

SLIT2_MOUSE
NC score	0.086330 (rank : 287)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	182	Target Neighborhood Hits	684	Shared Neighborhood Hits	75
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

FA9_HUMAN
NC score	0.086318 (rank : 288)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	182	Target Neighborhood Hits	421	Shared Neighborhood Hits	83
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

NETO2_MOUSE
NC score	0.086065 (rank : 289)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	182	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

FRAS1_HUMAN
NC score	0.085946 (rank : 290)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	182	Target Neighborhood Hits	759	Shared Neighborhood Hits	99
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF8_MOUSE
NC score	0.085936 (rank : 291)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	182	Target Neighborhood Hits	520	Shared Neighborhood Hits	82
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NETO2_HUMAN
NC score	0.085710 (rank : 292)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	182	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

KRA51_HUMAN
NC score	0.085294 (rank : 293)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	182	Target Neighborhood Hits	288	Shared Neighborhood Hits	63
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

CD97_MOUSE
NC score	0.084564 (rank : 294)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	182	Target Neighborhood Hits	295	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CSPG2_HUMAN
NC score	0.084446 (rank : 295)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	182	Target Neighborhood Hits	681	Shared Neighborhood Hits	66
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
NC score	0.084423 (rank : 296)	θ value	1.06291 (rank : 135)
Query Neighborhood Hits	182	Target Neighborhood Hits	711	Shared Neighborhood Hits	68
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

TMPS2_MOUSE
NC score	0.084356 (rank : 297)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	182	Target Neighborhood Hits	243	Shared Neighborhood Hits	64
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

CD248_HUMAN
NC score	0.084223 (rank : 298)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	182	Target Neighborhood Hits	679	Shared Neighborhood Hits	57
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ADA21_HUMAN
NC score	0.084185 (rank : 299)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	182	Target Neighborhood Hits	181	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

EDIL3_HUMAN
NC score	0.084139 (rank : 300)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	182	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

ADAM2_MOUSE
NC score	0.083977 (rank : 301)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	182	Target Neighborhood Hits	209	Shared Neighborhood Hits	78
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

EGFL8_MOUSE
NC score	0.083956 (rank : 302)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	182	Target Neighborhood Hits	266	Shared Neighborhood Hits	58
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

ADA25_MOUSE
NC score	0.083652 (rank : 303)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	182	Target Neighborhood Hits	213	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

SLIT3_MOUSE
NC score	0.082619 (rank : 304)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	182	Target Neighborhood Hits	700	Shared Neighborhood Hits	74
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ADA29_HUMAN
NC score	0.082578 (rank : 305)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	182	Target Neighborhood Hits	247	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

RXFP2_MOUSE
NC score	0.082367 (rank : 306)	θ value	0.125558 (rank : 112)
Query Neighborhood Hits	182	Target Neighborhood Hits	760	Shared Neighborhood Hits	63
SwissProt Accessions	Q91ZZ5	Gene names	Rxfp2, Gpr106, Great, Lgr8
Domain Architecture
Description	Relaxin receptor 2 (Relaxin family peptide receptor 2) (Leucine-rich repeat-containing G-protein coupled receptor 8) (G-protein coupled receptor affecting testicular descent) (G-protein coupled receptor 106).

ADA11_HUMAN
NC score	0.082318 (rank : 307)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	182	Target Neighborhood Hits	259	Shared Neighborhood Hits	72
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

EGFL8_HUMAN
NC score	0.082224 (rank : 308)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	182	Target Neighborhood Hits	270	Shared Neighborhood Hits	59
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

FA10_MOUSE
NC score	0.082153 (rank : 309)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	182	Target Neighborhood Hits	435	Shared Neighborhood Hits	79
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

EDIL3_MOUSE
NC score	0.081083 (rank : 310)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	182	Target Neighborhood Hits	317	Shared Neighborhood Hits	61
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

KRA53_HUMAN
NC score	0.080580 (rank : 311)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	182	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

HGFA_MOUSE
NC score	0.080562 (rank : 312)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	182	Target Neighborhood Hits	419	Shared Neighborhood Hits	71
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

PROC_MOUSE
NC score	0.080219 (rank : 313)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	182	Target Neighborhood Hits	426	Shared Neighborhood Hits	81
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

LAMA5_MOUSE
NC score	0.080154 (rank : 314)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	182	Target Neighborhood Hits	828	Shared Neighborhood Hits	85
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

EGFL7_MOUSE
NC score	0.079938 (rank : 315)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	182	Target Neighborhood Hits	287	Shared Neighborhood Hits	57
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

MATN3_MOUSE
NC score	0.079635 (rank : 316)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	182	Target Neighborhood Hits	261	Shared Neighborhood Hits	57
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

KR101_HUMAN
NC score	0.079626 (rank : 317)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	182	Target Neighborhood Hits	261	Shared Neighborhood Hits	55
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

FA10_HUMAN
NC score	0.079613 (rank : 318)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	182	Target Neighborhood Hits	431	Shared Neighborhood Hits	79
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

ADEC1_MOUSE
NC score	0.078746 (rank : 319)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	182	Target Neighborhood Hits	85	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

AD26A_MOUSE
NC score	0.078612 (rank : 320)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	182	Target Neighborhood Hits	165	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

HGFA_HUMAN
NC score	0.078282 (rank : 321)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	182	Target Neighborhood Hits	436	Shared Neighborhood Hits	72
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

FA7_HUMAN
NC score	0.077864 (rank : 322)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	182	Target Neighborhood Hits	404	Shared Neighborhood Hits	76
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

PCSK5_MOUSE
NC score	0.077563 (rank : 323)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	182	Target Neighborhood Hits	613	Shared Neighborhood Hits	93
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

ELTD1_HUMAN
NC score	0.077279 (rank : 324)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	182	Target Neighborhood Hits	269	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

CRIM1_HUMAN
NC score	0.077176 (rank : 325)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	182	Target Neighborhood Hits	362	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

TMPS3_MOUSE
NC score	0.076949 (rank : 326)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	182	Target Neighborhood Hits	239	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

NAGPA_HUMAN
NC score	0.076264 (rank : 327)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	182	Target Neighborhood Hits	282	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LAMA5_HUMAN
NC score	0.075830 (rank : 328)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	182	Target Neighborhood Hits	976	Shared Neighborhood Hits	82
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MATN3_HUMAN
NC score	0.075650 (rank : 329)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	182	Target Neighborhood Hits	268	Shared Neighborhood Hits	54
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

ADA17_HUMAN
NC score	0.074801 (rank : 330)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	182	Target Neighborhood Hits	223	Shared Neighborhood Hits	62
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

PROC_HUMAN
NC score	0.074465 (rank : 331)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	182	Target Neighborhood Hits	406	Shared Neighborhood Hits	80
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

FA12_HUMAN
NC score	0.074019 (rank : 332)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	182	Target Neighborhood Hits	425	Shared Neighborhood Hits	66
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

MATN4_HUMAN
NC score	0.073929 (rank : 333)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	182	Target Neighborhood Hits	287	Shared Neighborhood Hits	60
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

CSPG3_MOUSE
NC score	0.073598 (rank : 334)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	182	Target Neighborhood Hits	657	Shared Neighborhood Hits	61
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

KRA58_HUMAN
NC score	0.073505 (rank : 335)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	182	Target Neighborhood Hits	324	Shared Neighborhood Hits	53
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KR109_HUMAN
NC score	0.073129 (rank : 336)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	182	Target Neighborhood Hits	226	Shared Neighborhood Hits	53
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

ADA32_HUMAN
NC score	0.073091 (rank : 337)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	182	Target Neighborhood Hits	216	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

FA7_MOUSE
NC score	0.073027 (rank : 338)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	182	Target Neighborhood Hits	374	Shared Neighborhood Hits	68
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

RXFP1_HUMAN
NC score	0.072330 (rank : 339)	θ value	0.365318 (rank : 116)
Query Neighborhood Hits	182	Target Neighborhood Hits	816	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HBX9	Gene names	RXFP1, LGR7
Domain Architecture
Description	Relaxin receptor 1 (Relaxin family peptide receptor 1) (Leucine-rich repeat-containing G-protein coupled receptor 7).

LAMA1_MOUSE
NC score	0.072030 (rank : 340)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	182	Target Neighborhood Hits	838	Shared Neighborhood Hits	76
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

CSPG3_HUMAN
NC score	0.071340 (rank : 341)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	182	Target Neighborhood Hits	676	Shared Neighborhood Hits	62
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TMPS2_HUMAN
NC score	0.071047 (rank : 342)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	182	Target Neighborhood Hits	252	Shared Neighborhood Hits	54
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

MATN4_MOUSE
NC score	0.070756 (rank : 343)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	182	Target Neighborhood Hits	277	Shared Neighborhood Hits	61
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

TENR_MOUSE
NC score	0.070088 (rank : 344)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	182	Target Neighborhood Hits	531	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

KRA59_HUMAN
NC score	0.069092 (rank : 345)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	182	Target Neighborhood Hits	310	Shared Neighborhood Hits	47
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

WISP2_MOUSE
NC score	0.069020 (rank : 346)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	182	Target Neighborhood Hits	129	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ADA10_HUMAN
NC score	0.068909 (rank : 347)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	182	Target Neighborhood Hits	189	Shared Neighborhood Hits	55
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

TENR_HUMAN
NC score	0.068746 (rank : 348)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	182	Target Neighborhood Hits	526	Shared Neighborhood Hits	77
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

C1RA_MOUSE
NC score	0.067911 (rank : 349)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	182	Target Neighborhood Hits	379	Shared Neighborhood Hits	69
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

ADA17_MOUSE
NC score	0.067677 (rank : 350)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	182	Target Neighborhood Hits	201	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

MASP2_HUMAN
NC score	0.067487 (rank : 351)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	182	Target Neighborhood Hits	364	Shared Neighborhood Hits	61
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

ADA32_MOUSE
NC score	0.067401 (rank : 352)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	182	Target Neighborhood Hits	219	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

MASP2_MOUSE
NC score	0.067016 (rank : 353)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	182	Target Neighborhood Hits	382	Shared Neighborhood Hits	62
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

FAM5B_MOUSE
NC score	0.067000 (rank : 354)	θ value	1.06291 (rank : 137)
Query Neighborhood Hits	182	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

MASP1_HUMAN
NC score	0.066838 (rank : 355)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	182	Target Neighborhood Hits	369	Shared Neighborhood Hits	58
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

LAMC3_MOUSE
NC score	0.066776 (rank : 356)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	182	Target Neighborhood Hits	624	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

KR10B_HUMAN
NC score	0.066769 (rank : 357)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	182	Target Neighborhood Hits	269	Shared Neighborhood Hits	55
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LAMA1_HUMAN
NC score	0.066254 (rank : 358)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	182	Target Neighborhood Hits	804	Shared Neighborhood Hits	74
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

FATH_HUMAN
NC score	0.065894 (rank : 359)	θ value	0.279714 (rank : 114)
Query Neighborhood Hits	182	Target Neighborhood Hits	570	Shared Neighborhood Hits	73
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FAM5B_HUMAN
NC score	0.065733 (rank : 360)	θ value	0.47712 (rank : 118)
Query Neighborhood Hits	182	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

KRA98_HUMAN
NC score	0.065584 (rank : 361)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	182	Target Neighborhood Hits	185	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

NAGPA_MOUSE
NC score	0.065421 (rank : 362)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	182	Target Neighborhood Hits	308	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

ADAM2_HUMAN
NC score	0.065219 (rank : 363)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	182	Target Neighborhood Hits	175	Shared Neighborhood Hits	67
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

VWF_HUMAN
NC score	0.065215 (rank : 364)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	182	Target Neighborhood Hits	396	Shared Neighborhood Hits	72
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

C1RB_MOUSE
NC score	0.065167 (rank : 365)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	182	Target Neighborhood Hits	380	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1S_HUMAN
NC score	0.064650 (rank : 366)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	182	Target Neighborhood Hits	359	Shared Neighborhood Hits	69
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MASP1_MOUSE
NC score	0.064506 (rank : 367)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	182	Target Neighborhood Hits	364	Shared Neighborhood Hits	58
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

C1R_HUMAN
NC score	0.064316 (rank : 368)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	182	Target Neighborhood Hits	364	Shared Neighborhood Hits	62
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

ITB1_HUMAN
NC score	0.064186 (rank : 369)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	182	Target Neighborhood Hits	298	Shared Neighborhood Hits	67
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

WISP2_HUMAN
NC score	0.064133 (rank : 370)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	182	Target Neighborhood Hits	126	Shared Neighborhood Hits	46
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

LAMB2_HUMAN
NC score	0.064088 (rank : 371)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	182	Target Neighborhood Hits	692	Shared Neighborhood Hits	71
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

ADA18_MOUSE
NC score	0.063667 (rank : 372)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	182	Target Neighborhood Hits	227	Shared Neighborhood Hits	73
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

TPA_HUMAN
NC score	0.063587 (rank : 373)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	182	Target Neighborhood Hits	324	Shared Neighborhood Hits	65
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TLL1_MOUSE
NC score	0.063409 (rank : 374)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	182	Target Neighborhood Hits	237	Shared Neighborhood Hits	59
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

ATRN_HUMAN
NC score	0.063219 (rank : 375)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	182	Target Neighborhood Hits	525	Shared Neighborhood Hits	77
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

NFX1_HUMAN
NC score	0.063217 (rank : 376)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	182	Target Neighborhood Hits	405	Shared Neighborhood Hits	53
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

MEGF9_HUMAN
NC score	0.063003 (rank : 377)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	182	Target Neighborhood Hits	557	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CS1B_MOUSE
NC score	0.062931 (rank : 378)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	182	Target Neighborhood Hits	361	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

LAMC1_MOUSE
NC score	0.062782 (rank : 379)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	182	Target Neighborhood Hits	856	Shared Neighborhood Hits	73
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TLL1_HUMAN
NC score	0.062719 (rank : 380)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	182	Target Neighborhood Hits	236	Shared Neighborhood Hits	57
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

ADA10_MOUSE
NC score	0.062394 (rank : 381)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	182	Target Neighborhood Hits	194	Shared Neighborhood Hits	49
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

LAMC3_HUMAN
NC score	0.062372 (rank : 382)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	182	Target Neighborhood Hits	588	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

KRA93_HUMAN
NC score	0.061940 (rank : 383)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	182	Target Neighborhood Hits	203	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

TPA_MOUSE
NC score	0.061861 (rank : 384)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	182	Target Neighborhood Hits	335	Shared Neighborhood Hits	62
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

CS1A_MOUSE
NC score	0.061636 (rank : 385)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	182	Target Neighborhood Hits	360	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CO2_HUMAN
NC score	0.061347 (rank : 386)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	182	Target Neighborhood Hits	258	Shared Neighborhood Hits	26
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

TMPS4_HUMAN
NC score	0.061271 (rank : 387)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	182	Target Neighborhood Hits	203	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

LAMA2_MOUSE
NC score	0.061209 (rank : 388)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	182	Target Neighborhood Hits	1198	Shared Neighborhood Hits	75
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

BMP1_MOUSE
NC score	0.061010 (rank : 389)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	182	Target Neighborhood Hits	236	Shared Neighborhood Hits	56
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_HUMAN
NC score	0.060933 (rank : 390)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	182	Target Neighborhood Hits	241	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

ADA20_HUMAN
NC score	0.060862 (rank : 391)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	182	Target Neighborhood Hits	143	Shared Neighborhood Hits	51
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

LAMB1_HUMAN
NC score	0.060703 (rank : 392)	θ value	4.03905 (rank : 159)
Query Neighborhood Hits	182	Target Neighborhood Hits	1018	Shared Neighborhood Hits	68
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KR105_HUMAN
NC score	0.060531 (rank : 393)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	182	Target Neighborhood Hits	271	Shared Neighborhood Hits	49
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

BMP1_HUMAN
NC score	0.060521 (rank : 394)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	182	Target Neighborhood Hits	233	Shared Neighborhood Hits	55
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

USH2A_MOUSE
NC score	0.060458 (rank : 395)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	182	Target Neighborhood Hits	626	Shared Neighborhood Hits	64
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

TLL2_MOUSE
NC score	0.059991 (rank : 396)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	182	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

EMR3_HUMAN
NC score	0.059944 (rank : 397)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	182	Target Neighborhood Hits	245	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

KR10C_HUMAN
NC score	0.059874 (rank : 398)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	182	Target Neighborhood Hits	219	Shared Neighborhood Hits	46
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LAMB2_MOUSE
NC score	0.059871 (rank : 399)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	182	Target Neighborhood Hits	722	Shared Neighborhood Hits	67
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

KR108_HUMAN
NC score	0.059711 (rank : 400)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	182	Target Neighborhood Hits	226	Shared Neighborhood Hits	47
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LAMA2_HUMAN
NC score	0.059579 (rank : 401)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	182	Target Neighborhood Hits	1092	Shared Neighborhood Hits	70
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC1_HUMAN
NC score	0.059569 (rank : 402)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	182	Target Neighborhood Hits	922	Shared Neighborhood Hits	73
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

ITB3_HUMAN
NC score	0.059502 (rank : 403)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	182	Target Neighborhood Hits	325	Shared Neighborhood Hits	68
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

RECK_HUMAN
NC score	0.059235 (rank : 404)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	182	Target Neighborhood Hits	189	Shared Neighborhood Hits	46
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

LYAM2_MOUSE
NC score	0.059048 (rank : 405)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	182	Target Neighborhood Hits	420	Shared Neighborhood Hits	71
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KRA92_HUMAN
NC score	0.058859 (rank : 406)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	182	Target Neighborhood Hits	198	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LAMC2_HUMAN
NC score	0.058687 (rank : 407)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	182	Target Neighborhood Hits	715	Shared Neighborhood Hits	68
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

RSPO1_HUMAN
NC score	0.058681 (rank : 408)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	182	Target Neighborhood Hits	101	Shared Neighborhood Hits	39
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

WISP1_MOUSE
NC score	0.058453 (rank : 409)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	182	Target Neighborhood Hits	123	Shared Neighborhood Hits	43
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ATRN_MOUSE
NC score	0.058389 (rank : 410)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	182	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ITB5_MOUSE
NC score	0.058261 (rank : 411)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	182	Target Neighborhood Hits	329	Shared Neighborhood Hits	70
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

NTNG2_HUMAN
NC score	0.058059 (rank : 412)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	182	Target Neighborhood Hits	276	Shared Neighborhood Hits	61
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

KRA13_HUMAN
NC score	0.057890 (rank : 413)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	182	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

LYAM2_HUMAN
NC score	0.057868 (rank : 414)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	182	Target Neighborhood Hits	394	Shared Neighborhood Hits	67
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LAMB1_MOUSE
NC score	0.057860 (rank : 415)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	182	Target Neighborhood Hits	919	Shared Neighborhood Hits	64
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

TNR26_MOUSE
NC score	0.057749 (rank : 416)	θ value	0.47712 (rank : 123)
Query Neighborhood Hits	182	Target Neighborhood Hits	106	Shared Neighborhood Hits	17
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TMPS4_MOUSE
NC score	0.057737 (rank : 417)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	182	Target Neighborhood Hits	210	Shared Neighborhood Hits	39
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

MFGM_MOUSE
NC score	0.057663 (rank : 418)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	182	Target Neighborhood Hits	233	Shared Neighborhood Hits	51
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

CELR2_HUMAN
NC score	0.057535 (rank : 419)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	182	Target Neighborhood Hits	657	Shared Neighborhood Hits	83
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

LAMA3_MOUSE
NC score	0.057520 (rank : 420)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	182	Target Neighborhood Hits	859	Shared Neighborhood Hits	77
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

KRA94_HUMAN
NC score	0.057450 (rank : 421)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	182	Target Neighborhood Hits	204	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

ITB6_MOUSE
NC score	0.057331 (rank : 422)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	182	Target Neighborhood Hits	341	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

WISP1_HUMAN
NC score	0.057085 (rank : 423)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	182	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

LYAM3_HUMAN
NC score	0.057084 (rank : 424)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	182	Target Neighborhood Hits	378	Shared Neighborhood Hits	61
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

ITB7_MOUSE
NC score	0.056649 (rank : 425)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	182	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

LYAM3_MOUSE
NC score	0.056618 (rank : 426)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	182	Target Neighborhood Hits	390	Shared Neighborhood Hits	58
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

FAM5C_MOUSE
NC score	0.056507 (rank : 427)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	182	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	Q499E0, Q8K0R9	Gene names	Fam5c
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor.

KR412_HUMAN
NC score	0.056450 (rank : 428)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	182	Target Neighborhood Hits	178	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

HHIP_HUMAN
NC score	0.056208 (rank : 429)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	182	Target Neighborhood Hits	249	Shared Neighborhood Hits	47
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

NTNG2_MOUSE
NC score	0.055667 (rank : 430)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	182	Target Neighborhood Hits	276	Shared Neighborhood Hits	60
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG1_MOUSE
NC score	0.055260 (rank : 431)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	182	Target Neighborhood Hits	246	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

FAM5C_HUMAN
NC score	0.055213 (rank : 432)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	182	Target Neighborhood Hits	21	Shared Neighborhood Hits	12
SwissProt Accessions	Q76B58, O95726	Gene names	FAM5C, DBCCR1L, DBCCR1L1
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor (DBCCR1-like protein 1).

ZAN_HUMAN
NC score	0.055089 (rank : 433)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	182	Target Neighborhood Hits	679	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

TENN_HUMAN
NC score	0.054994 (rank : 434)	θ value	1.81305 (rank : 147)
Query Neighborhood Hits	182	Target Neighborhood Hits	453	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

KR414_HUMAN
NC score	0.054972 (rank : 435)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	182	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

ITB6_HUMAN
NC score	0.054867 (rank : 436)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	182	Target Neighborhood Hits	318	Shared Neighborhood Hits	68
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

CFAB_HUMAN
NC score	0.054776 (rank : 437)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	182	Target Neighborhood Hits	251	Shared Neighborhood Hits	25
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

ITB5_HUMAN
NC score	0.054776 (rank : 438)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	182	Target Neighborhood Hits	310	Shared Neighborhood Hits	69
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

CELR3_HUMAN
NC score	0.054526 (rank : 439)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	182	Target Neighborhood Hits	680	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

UROK_HUMAN
NC score	0.054442 (rank : 440)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	182	Target Neighborhood Hits	272	Shared Neighborhood Hits	56
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

KRA57_HUMAN
NC score	0.054436 (rank : 441)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	182	Target Neighborhood Hits	269	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

RSPO1_MOUSE
NC score	0.054370 (rank : 442)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	182	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

TMPSD_HUMAN
NC score	0.054338 (rank : 443)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	182	Target Neighborhood Hits	333	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

MUC5B_HUMAN
NC score	0.054332 (rank : 444)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	182	Target Neighborhood Hits	1020	Shared Neighborhood Hits	72
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

CO2_MOUSE
NC score	0.054196 (rank : 445)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	182	Target Neighborhood Hits	250	Shared Neighborhood Hits	25
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

LCE3B_HUMAN
NC score	0.054168 (rank : 446)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	182	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

TENN_MOUSE
NC score	0.054064 (rank : 447)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	182	Target Neighborhood Hits	484	Shared Neighborhood Hits	70
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

UROK_MOUSE
NC score	0.053907 (rank : 448)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	182	Target Neighborhood Hits	273	Shared Neighborhood Hits	55
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

HHIP_MOUSE
NC score	0.053718 (rank : 449)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	182	Target Neighborhood Hits	219	Shared Neighborhood Hits	44
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KRA15_HUMAN
NC score	0.053691 (rank : 450)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	182	Target Neighborhood Hits	126	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

TM11E_HUMAN
NC score	0.053265 (rank : 451)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	182	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

KR511_HUMAN
NC score	0.053209 (rank : 452)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	182	Target Neighborhood Hits	231	Shared Neighborhood Hits	33
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

MEGF9_MOUSE
NC score	0.053208 (rank : 453)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	182	Target Neighborhood Hits	896	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TMPSD_MOUSE
NC score	0.053029 (rank : 454)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	182	Target Neighborhood Hits	334	Shared Neighborhood Hits	27
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

KRA44_HUMAN
NC score	0.052997 (rank : 455)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	182	Target Neighborhood Hits	162	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA99_HUMAN
NC score	0.052799 (rank : 456)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	182	Target Neighborhood Hits	173	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

CFC1_MOUSE
NC score	0.052729 (rank : 457)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	182	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CELR1_HUMAN
NC score	0.052714 (rank : 458)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	182	Target Neighborhood Hits	613	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CFC1_HUMAN
NC score	0.052504 (rank : 459)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	182	Target Neighborhood Hits	148	Shared Neighborhood Hits	44
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

ITB4_HUMAN
NC score	0.052379 (rank : 460)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	182	Target Neighborhood Hits	458	Shared Neighborhood Hits	62
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KRA11_HUMAN
NC score	0.052326 (rank : 461)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	182	Target Neighborhood Hits	155	Shared Neighborhood Hits	34
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

TDGF1_MOUSE
NC score	0.052270 (rank : 462)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	182	Target Neighborhood Hits	146	Shared Neighborhood Hits	43
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TM11E_MOUSE
NC score	0.052117 (rank : 463)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	182	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

USH2A_HUMAN
NC score	0.052053 (rank : 464)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	182	Target Neighborhood Hits	600	Shared Neighborhood Hits	67
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

CFAB_MOUSE
NC score	0.051828 (rank : 465)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	182	Target Neighborhood Hits	262	Shared Neighborhood Hits	25
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CELR1_MOUSE
NC score	0.051716 (rank : 466)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	182	Target Neighborhood Hits	617	Shared Neighborhood Hits	71
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

NTNG1_HUMAN
NC score	0.051668 (rank : 467)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	182	Target Neighborhood Hits	247	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

CELR3_MOUSE
NC score	0.051556 (rank : 468)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	182	Target Neighborhood Hits	687	Shared Neighborhood Hits	72
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CYR61_HUMAN
NC score	0.051514 (rank : 469)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	182	Target Neighborhood Hits	159	Shared Neighborhood Hits	51
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

TM11D_MOUSE
NC score	0.051284 (rank : 470)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	182	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

ITB1_MOUSE
NC score	0.051201 (rank : 471)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	182	Target Neighborhood Hits	283	Shared Neighborhood Hits	61
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

DESC4_MOUSE
NC score	0.051152 (rank : 472)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	182	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

LAMC2_MOUSE
NC score	0.051065 (rank : 473)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	182	Target Neighborhood Hits	614	Shared Neighborhood Hits	61
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

FAM5A_HUMAN
NC score	0.050905 (rank : 474)	θ value	5.27518 (rank : 166)
Query Neighborhood Hits	182	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O60477, Q6IPV6, Q6P1A0, Q8WU22	Gene names	FAM5A, DBC1, DBCCR1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein).

ADA18_HUMAN
NC score	0.050872 (rank : 475)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	182	Target Neighborhood Hits	184	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

VWF_MOUSE
NC score	0.050864 (rank : 476)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	182	Target Neighborhood Hits	381	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FAM5A_MOUSE
NC score	0.050831 (rank : 477)	θ value	5.27518 (rank : 167)
Query Neighborhood Hits	182	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q920P3, Q80ZL2, Q812F0, Q8C1C9, Q920P4, Q9QXL0	Gene names	Fam5a, Brinp, Brinp1, Dbccr1
Domain Architecture	No domain graphic available
Description	Protein FAM5A precursor (Deleted in bladder cancer 1 protein homolog) (BMP/retinoic acid-inducible neural-specific protein 1).

TEST_HUMAN
NC score	0.050766 (rank : 478)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	182	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

POLS2_HUMAN
NC score	0.050731 (rank : 479)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	182	Target Neighborhood Hits	192	Shared Neighborhood Hits	21
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

TMPS5_HUMAN
NC score	0.050546 (rank : 480)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	182	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

ITB3_MOUSE
NC score	0.050206 (rank : 481)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	182	Target Neighborhood Hits	319	Shared Neighborhood Hits	61
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

TMPS5_MOUSE
NC score	0.050176 (rank : 482)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	182	Target Neighborhood Hits	185	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

ITB7_HUMAN
NC score	0.050174 (rank : 483)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	182	Target Neighborhood Hits	290	Shared Neighborhood Hits	60
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LAMB3_MOUSE
NC score	0.050114 (rank : 484)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	182	Target Neighborhood Hits	444	Shared Neighborhood Hits	59
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

DOCK4_MOUSE
NC score	0.011316 (rank : 485)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	182	Target Neighborhood Hits	210	Shared Neighborhood Hits	7
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DOCK4_HUMAN
NC score	0.011238 (rank : 486)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	182	Target Neighborhood Hits	237	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1I0, O14584, O94824, Q8NB45	Gene names	DOCK4, KIAA0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

C209D_MOUSE
NC score	0.010624 (rank : 487)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	182	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q91ZW8, Q8VIK4	Gene names	Cd209d
Domain Architecture
Description	CD209 antigen-like protein D (DC-SIGN-related protein 3) (DC-SIGNR3).

C209E_MOUSE
NC score	0.008426 (rank : 488)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	182	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZW7	Gene names	Cd209e
Domain Architecture
Description	CD209 antigen-like protein E (DC-SIGN-related protein 4) (DC-SIGNR4).