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Network neighborhood for query Sequence : SPON2_MOUSE

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SPON2_MOUSE
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPON2_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

SPON2_HUMAN
θ value	8.04023e-158 (rank : 2)	NC score	0.989204 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON1_MOUSE
θ value	9.83387e-39 (rank : 3)	NC score	0.560920 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	123	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
θ value	1.6774e-38 (rank : 4)	NC score	0.559746 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	117	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

RSPO2_MOUSE
θ value	7.1131e-05 (rank : 5)	NC score	0.312237 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO2_HUMAN
θ value	0.00020696 (rank : 6)	NC score	0.308550 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	90	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

CO8B_HUMAN
θ value	0.000602161 (rank : 7)	NC score	0.177526 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	199	Shared Neighborhood Hits	30
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

RSPO1_MOUSE
θ value	0.00102713 (rank : 8)	NC score	0.310695 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO1_HUMAN
θ value	0.00665767 (rank : 9)	NC score	0.303294 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	101	Shared Neighborhood Hits	30
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO3_HUMAN
θ value	0.00665767 (rank : 10)	NC score	0.293607 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	128	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	0.0148317 (rank : 11)	NC score	0.291184 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	120	Shared Neighborhood Hits	25
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

SSPO_MOUSE
θ value	0.0736092 (rank : 12)	NC score	0.135104 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	800	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

PROP_HUMAN
θ value	0.0961366 (rank : 13)	NC score	0.192291 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	126	Shared Neighborhood Hits	37
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

BAI1_HUMAN
θ value	0.163984 (rank : 14)	NC score	0.161010 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	375	Shared Neighborhood Hits	38
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	0.163984 (rank : 15)	NC score	0.159260 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	340	Shared Neighborhood Hits	36
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

CO8B_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.148904 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	224	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CILP1_HUMAN
θ value	0.279714 (rank : 17)	NC score	0.143169 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	266	Shared Neighborhood Hits	31
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.133832 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	282	Shared Neighborhood Hits	28
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

HMCN1_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.084036 (rank : 52)
Query Neighborhood Hits	42	Target Neighborhood Hits	983	Shared Neighborhood Hits	35
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CO9_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.124064 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	153	Shared Neighborhood Hits	20
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CO9_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.127133 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

SON_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.013875 (rank : 84)
Query Neighborhood Hits	42	Target Neighborhood Hits	1568	Shared Neighborhood Hits	6
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TSP1_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.121697 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	389	Shared Neighborhood Hits	35
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	1.38821 (rank : 24)	NC score	0.122621 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	396	Shared Neighborhood Hits	35
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

BAI3_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.150495 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	246	Shared Neighborhood Hits	36
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	1.81305 (rank : 26)	NC score	0.149950 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	250	Shared Neighborhood Hits	34
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

OSBL7_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.019370 (rank : 83)
Query Neighborhood Hits	42	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

SEM5B_MOUSE
θ value	2.36792 (rank : 28)	NC score	0.113470 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	190	Shared Neighborhood Hits	32
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

ATS17_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.080060 (rank : 56)
Query Neighborhood Hits	42	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

KYNU_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.028230 (rank : 82)
Query Neighborhood Hits	42	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q16719	Gene names	KYNU
Domain Architecture	No domain graphic available
Description	Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase).

ATS14_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.069805 (rank : 64)
Query Neighborhood Hits	42	Target Neighborhood Hits	382	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

SEM5A_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.112014 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	177	Shared Neighborhood Hits	30
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

RSPO4_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.209046 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	110	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

CO7_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.103383 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	278	Shared Neighborhood Hits	32
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.094503 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	182	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

BAI2_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.148174 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	332	Shared Neighborhood Hits	36
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.147637 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	323	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CILP2_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.127059 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

OST4_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.006726 (rank : 85)
Query Neighborhood Hits	42	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

TSP2_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.123424 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	359	Shared Neighborhood Hits	35
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

UNC5C_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.102447 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	226	Shared Neighborhood Hits	30
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.102487 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	225	Shared Neighborhood Hits	29
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

ATL1_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.055176 (rank : 78)
Query Neighborhood Hits	42	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

ATL2_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.094300 (rank : 48)
Query Neighborhood Hits	42	Target Neighborhood Hits	125	Shared Neighborhood Hits	24
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.094435 (rank : 45)
Query Neighborhood Hits	42	Target Neighborhood Hits	137	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL3_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.069674 (rank : 65)
Query Neighborhood Hits	42	Target Neighborhood Hits	414	Shared Neighborhood Hits	27
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATL5_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.061808 (rank : 74)
Query Neighborhood Hits	42	Target Neighborhood Hits	103	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATS12_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.063922 (rank : 72)
Query Neighborhood Hits	42	Target Neighborhood Hits	251	Shared Neighborhood Hits	29
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.065624 (rank : 69)
Query Neighborhood Hits	42	Target Neighborhood Hits	220	Shared Neighborhood Hits	29
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS13_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.068619 (rank : 67)
Query Neighborhood Hits	42	Target Neighborhood Hits	238	Shared Neighborhood Hits	29
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.062341 (rank : 73)
Query Neighborhood Hits	42	Target Neighborhood Hits	227	Shared Neighborhood Hits	29
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS16_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.076574 (rank : 59)
Query Neighborhood Hits	42	Target Neighborhood Hits	208	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.077811 (rank : 57)
Query Neighborhood Hits	42	Target Neighborhood Hits	179	Shared Neighborhood Hits	33
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS18_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.077151 (rank : 58)
Query Neighborhood Hits	42	Target Neighborhood Hits	169	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.082505 (rank : 54)
Query Neighborhood Hits	42	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS19_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.068795 (rank : 66)
Query Neighborhood Hits	42	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.072062 (rank : 62)
Query Neighborhood Hits	42	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS1_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.055282 (rank : 77)
Query Neighborhood Hits	42	Target Neighborhood Hits	159	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATS1_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.058011 (rank : 76)
Query Neighborhood Hits	42	Target Neighborhood Hits	158	Shared Neighborhood Hits	29
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS20_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.074206 (rank : 60)
Query Neighborhood Hits	42	Target Neighborhood Hits	192	Shared Neighborhood Hits	34
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.081450 (rank : 55)
Query Neighborhood Hits	42	Target Neighborhood Hits	225	Shared Neighborhood Hits	34
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS2_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.066366 (rank : 68)
Query Neighborhood Hits	42	Target Neighborhood Hits	179	Shared Neighborhood Hits	30
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS2_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.064030 (rank : 71)
Query Neighborhood Hits	42	Target Neighborhood Hits	179	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS3_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.060951 (rank : 75)
Query Neighborhood Hits	42	Target Neighborhood Hits	179	Shared Neighborhood Hits	31
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS6_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.050668 (rank : 81)
Query Neighborhood Hits	42	Target Neighborhood Hits	141	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS8_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.050739 (rank : 80)
Query Neighborhood Hits	42	Target Neighborhood Hits	145	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS9_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.083569 (rank : 53)
Query Neighborhood Hits	42	Target Neighborhood Hits	219	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

CI094_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.064874 (rank : 70)
Query Neighborhood Hits	42	Target Neighborhood Hits	310	Shared Neighborhood Hits	22
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CO6_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.128529 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	331	Shared Neighborhood Hits	32
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.093056 (rank : 49)
Query Neighborhood Hits	42	Target Neighborhood Hits	200	Shared Neighborhood Hits	28
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

KR414_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.053715 (rank : 79)
Query Neighborhood Hits	42	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

PROP_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.184389 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	165	Shared Neighborhood Hits	35
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

RELN_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.073174 (rank : 61)
Query Neighborhood Hits	42	Target Neighborhood Hits	233	Shared Neighborhood Hits	2
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.070967 (rank : 63)
Query Neighborhood Hits	42	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RSPO4_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.168425 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	110	Shared Neighborhood Hits	19
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SEM5A_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.109560 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	162	Shared Neighborhood Hits	29
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5B_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.103374 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

THSD1_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.087501 (rank : 50)
Query Neighborhood Hits	42	Target Neighborhood Hits	136	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

THSD1_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.086178 (rank : 51)
Query Neighborhood Hits	42	Target Neighborhood Hits	153	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

TSP2_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.119495 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	352	Shared Neighborhood Hits	33
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

UNC5A_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.099700 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	203	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.103361 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	225	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.102961 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	226	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5D_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.094403 (rank : 46)
Query Neighborhood Hits	42	Target Neighborhood Hits	267	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.094335 (rank : 47)
Query Neighborhood Hits	42	Target Neighborhood Hits	268	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

Hits sorted by NC score

SPON2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

SPON2_HUMAN
NC score	0.989204 (rank : 2)	θ value	8.04023e-158 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BUD6, Q9ULW1	Gene names	SPON2, DIL1
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin) (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1).

SPON1_MOUSE
NC score	0.560920 (rank : 3)	θ value	9.83387e-39 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	123	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPON1_HUMAN
NC score	0.559746 (rank : 4)	θ value	1.6774e-38 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	117	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

RSPO2_MOUSE
NC score	0.312237 (rank : 5)	θ value	7.1131e-05 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO1_MOUSE
NC score	0.310695 (rank : 6)	θ value	0.00102713 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO2_HUMAN
NC score	0.308550 (rank : 7)	θ value	0.00020696 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	90	Shared Neighborhood Hits	21
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO1_HUMAN
NC score	0.303294 (rank : 8)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	101	Shared Neighborhood Hits	30
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO3_HUMAN
NC score	0.293607 (rank : 9)	θ value	0.00665767 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	128	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
NC score	0.291184 (rank : 10)	θ value	0.0148317 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	120	Shared Neighborhood Hits	25
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_MOUSE
NC score	0.209046 (rank : 11)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	110	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

PROP_HUMAN
NC score	0.192291 (rank : 12)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	126	Shared Neighborhood Hits	37
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
NC score	0.184389 (rank : 13)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	42	Target Neighborhood Hits	165	Shared Neighborhood Hits	35
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

CO8B_HUMAN
NC score	0.177526 (rank : 14)	θ value	0.000602161 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	199	Shared Neighborhood Hits	30
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

RSPO4_HUMAN
NC score	0.168425 (rank : 15)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	42	Target Neighborhood Hits	110	Shared Neighborhood Hits	19
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

BAI1_HUMAN
NC score	0.161010 (rank : 16)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	375	Shared Neighborhood Hits	38
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
NC score	0.159260 (rank : 17)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	340	Shared Neighborhood Hits	36
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI3_HUMAN
NC score	0.150495 (rank : 18)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	246	Shared Neighborhood Hits	36
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
NC score	0.149950 (rank : 19)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	250	Shared Neighborhood Hits	34
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CO8B_MOUSE
NC score	0.148904 (rank : 20)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	224	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

BAI2_HUMAN
NC score	0.148174 (rank : 21)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	332	Shared Neighborhood Hits	36
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
NC score	0.147637 (rank : 22)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	323	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CILP1_HUMAN
NC score	0.143169 (rank : 23)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	266	Shared Neighborhood Hits	31
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

SSPO_MOUSE
NC score	0.135104 (rank : 24)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	800	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CILP1_MOUSE
NC score	0.133832 (rank : 25)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	282	Shared Neighborhood Hits	28
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CO6_HUMAN
NC score	0.128529 (rank : 26)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	42	Target Neighborhood Hits	331	Shared Neighborhood Hits	32
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO9_HUMAN
NC score	0.127133 (rank : 27)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CILP2_HUMAN
NC score	0.127059 (rank : 28)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	307	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CO9_MOUSE
NC score	0.124064 (rank : 29)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	153	Shared Neighborhood Hits	20
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

TSP2_HUMAN
NC score	0.123424 (rank : 30)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	359	Shared Neighborhood Hits	35
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP1_MOUSE
NC score	0.122621 (rank : 31)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	396	Shared Neighborhood Hits	35
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_HUMAN
NC score	0.121697 (rank : 32)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	389	Shared Neighborhood Hits	35
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_MOUSE
NC score	0.119495 (rank : 33)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	42	Target Neighborhood Hits	352	Shared Neighborhood Hits	33
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

SEM5B_MOUSE
NC score	0.113470 (rank : 34)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	190	Shared Neighborhood Hits	32
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SEM5A_HUMAN
NC score	0.112014 (rank : 35)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	177	Shared Neighborhood Hits	30
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
NC score	0.109560 (rank : 36)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	42	Target Neighborhood Hits	162	Shared Neighborhood Hits	29
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

CO7_HUMAN
NC score	0.103383 (rank : 37)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	278	Shared Neighborhood Hits	32
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

SEM5B_HUMAN
NC score	0.103374 (rank : 38)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	42	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

UNC5B_HUMAN
NC score	0.103361 (rank : 39)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	42	Target Neighborhood Hits	225	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
NC score	0.102961 (rank : 40)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	42	Target Neighborhood Hits	226	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_MOUSE
NC score	0.102487 (rank : 41)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	225	Shared Neighborhood Hits	29
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5C_HUMAN
NC score	0.102447 (rank : 42)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	226	Shared Neighborhood Hits	30
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5A_MOUSE
NC score	0.099700 (rank : 43)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	42	Target Neighborhood Hits	203	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

CO8A_MOUSE
NC score	0.094503 (rank : 44)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	182	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ATL2_MOUSE
NC score	0.094435 (rank : 45)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	42	Target Neighborhood Hits	137	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

UNC5D_HUMAN
NC score	0.094403 (rank : 46)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	42	Target Neighborhood Hits	267	Shared Neighborhood Hits	28
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
NC score	0.094335 (rank : 47)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	42	Target Neighborhood Hits	268	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

ATL2_HUMAN
NC score	0.094300 (rank : 48)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	125	Shared Neighborhood Hits	24
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

CO8A_HUMAN
NC score	0.093056 (rank : 49)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	42	Target Neighborhood Hits	200	Shared Neighborhood Hits	28
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

THSD1_HUMAN
NC score	0.087501 (rank : 50)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	42	Target Neighborhood Hits	136	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NS62, Q6P3U1, Q6UXZ2	Gene names	THSD1, TMTSP
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

THSD1_MOUSE
NC score	0.086178 (rank : 51)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	42	Target Neighborhood Hits	153	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JM61, Q8C7Q9	Gene names	Thsd1, Tmtsp
Domain Architecture	No domain graphic available
Description	Thrombospondin type-1 domain-containing protein 1 precursor (Transmembrane molecule with thrombospondin module).

HMCN1_HUMAN
NC score	0.084036 (rank : 52)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	983	Shared Neighborhood Hits	35
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ATS9_HUMAN
NC score	0.083569 (rank : 53)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	42	Target Neighborhood Hits	219	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

ATS18_MOUSE
NC score	0.082505 (rank : 54)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	42	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS20_MOUSE
NC score	0.081450 (rank : 55)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	42	Target Neighborhood Hits	225	Shared Neighborhood Hits	34
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS17_HUMAN
NC score	0.080060 (rank : 56)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS16_MOUSE
NC score	0.077811 (rank : 57)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	42	Target Neighborhood Hits	179	Shared Neighborhood Hits	33
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS18_HUMAN
NC score	0.077151 (rank : 58)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	42	Target Neighborhood Hits	169	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS16_HUMAN
NC score	0.076574 (rank : 59)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	42	Target Neighborhood Hits	208	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS20_HUMAN
NC score	0.074206 (rank : 60)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	42	Target Neighborhood Hits	192	Shared Neighborhood Hits	34
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

RELN_HUMAN
NC score	0.073174 (rank : 61)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	42	Target Neighborhood Hits	233	Shared Neighborhood Hits	2
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

ATS19_MOUSE
NC score	0.072062 (rank : 62)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	42	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

RELN_MOUSE
NC score	0.070967 (rank : 63)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	42	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

ATS14_HUMAN
NC score	0.069805 (rank : 64)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	382	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATL3_HUMAN
NC score	0.069674 (rank : 65)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	42	Target Neighborhood Hits	414	Shared Neighborhood Hits	27
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATS19_HUMAN
NC score	0.068795 (rank : 66)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	42	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS13_HUMAN
NC score	0.068619 (rank : 67)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	42	Target Neighborhood Hits	238	Shared Neighborhood Hits	29
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS2_HUMAN
NC score	0.066366 (rank : 68)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	42	Target Neighborhood Hits	179	Shared Neighborhood Hits	30
SwissProt Accessions	O95450	Gene names	ADAMTS2, PCINP, PCPNI
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS12_MOUSE
NC score	0.065624 (rank : 69)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	42	Target Neighborhood Hits	220	Shared Neighborhood Hits	29
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

CI094_HUMAN
NC score	0.064874 (rank : 70)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	42	Target Neighborhood Hits	310	Shared Neighborhood Hits	22
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ATS2_MOUSE
NC score	0.064030 (rank : 71)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	42	Target Neighborhood Hits	179	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

ATS12_HUMAN
NC score	0.063922 (rank : 72)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	42	Target Neighborhood Hits	251	Shared Neighborhood Hits	29
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS13_MOUSE
NC score	0.062341 (rank : 73)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	42	Target Neighborhood Hits	227	Shared Neighborhood Hits	29
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATL5_HUMAN
NC score	0.061808 (rank : 74)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	42	Target Neighborhood Hits	103	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZMM2, Q8IW95	Gene names	ADAMTSL5, THSD6
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 5 precursor (ADAMTSL-5) (Thrombospondin type-1 domain-containing protein 6).

ATS3_HUMAN
NC score	0.060951 (rank : 75)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	42	Target Neighborhood Hits	179	Shared Neighborhood Hits	31
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS1_MOUSE
NC score	0.058011 (rank : 76)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	42	Target Neighborhood Hits	158	Shared Neighborhood Hits	29
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS1_HUMAN
NC score	0.055282 (rank : 77)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	42	Target Neighborhood Hits	159	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ATL1_HUMAN
NC score	0.055176 (rank : 78)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N6G6, Q5T708, Q96RW4, Q9BXY3	Gene names	ADAMTSL1, ADAMTSR1
Domain Architecture
Description	ADAMTS-like protein 1 precursor (ADAMTSL-1) (Punctin-1).

KR414_HUMAN
NC score	0.053715 (rank : 79)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	42	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

ATS8_HUMAN
NC score	0.050739 (rank : 80)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	42	Target Neighborhood Hits	145	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATS6_HUMAN
NC score	0.050668 (rank : 81)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	42	Target Neighborhood Hits	141	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

KYNU_HUMAN
NC score	0.028230 (rank : 82)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q16719	Gene names	KYNU
Domain Architecture	No domain graphic available
Description	Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase).

OSBL7_HUMAN
NC score	0.019370 (rank : 83)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

SON_HUMAN
NC score	0.013875 (rank : 84)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	1568	Shared Neighborhood Hits	6
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

OST4_HUMAN
NC score	0.006726 (rank : 85)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).