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Network neighborhood for query Sequence : OST4_HUMAN

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OST4_HUMAN
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OST4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST3A_HUMAN
θ value	4.92331e-123 (rank : 2)	NC score	0.988578 (rank : 2)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST3B_HUMAN
θ value	1.87085e-122 (rank : 3)	NC score	0.987161 (rank : 4)
Query Neighborhood Hits	95	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST2_MOUSE
θ value	1.58377e-121 (rank : 4)	NC score	0.986981 (rank : 5)
Query Neighborhood Hits	95	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST2_HUMAN
θ value	2.06847e-121 (rank : 5)	NC score	0.987221 (rank : 3)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST3A_MOUSE
θ value	2.36663e-117 (rank : 6)	NC score	0.986785 (rank : 8)
Query Neighborhood Hits	95	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3B_MOUSE
θ value	1.8752e-114 (rank : 7)	NC score	0.986335 (rank : 9)
Query Neighborhood Hits	95	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST6_HUMAN
θ value	1.02895e-112 (rank : 8)	NC score	0.986969 (rank : 6)
Query Neighborhood Hits	95	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST6_MOUSE
θ value	8.71062e-112 (rank : 9)	NC score	0.986890 (rank : 7)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

OST5_MOUSE
θ value	7.2256e-66 (rank : 10)	NC score	0.963538 (rank : 13)
Query Neighborhood Hits	95	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

OST5_HUMAN
θ value	1.2325e-65 (rank : 11)	NC score	0.963539 (rank : 12)
Query Neighborhood Hits	95	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST1_HUMAN
θ value	9.1404e-61 (rank : 12)	NC score	0.964150 (rank : 10)
Query Neighborhood Hits	95	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST1_MOUSE
θ value	1.19377e-60 (rank : 13)	NC score	0.964131 (rank : 11)
Query Neighborhood Hits	95	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

NDST3_HUMAN
θ value	1.6813e-30 (rank : 14)	NC score	0.760467 (rank : 14)
Query Neighborhood Hits	95	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST4_HUMAN
θ value	7.06379e-29 (rank : 15)	NC score	0.758750 (rank : 15)
Query Neighborhood Hits	95	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST3_MOUSE
θ value	1.2049e-28 (rank : 16)	NC score	0.755446 (rank : 18)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST4_MOUSE
θ value	2.05525e-28 (rank : 17)	NC score	0.756569 (rank : 17)
Query Neighborhood Hits	95	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST2_HUMAN
θ value	4.57862e-28 (rank : 18)	NC score	0.758491 (rank : 16)
Query Neighborhood Hits	95	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST2_MOUSE
θ value	3.87602e-27 (rank : 19)	NC score	0.754720 (rank : 19)
Query Neighborhood Hits	95	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST1_HUMAN
θ value	2.51237e-26 (rank : 20)	NC score	0.743833 (rank : 20)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_MOUSE
θ value	7.30988e-26 (rank : 21)	NC score	0.743290 (rank : 21)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

ST4S6_MOUSE
θ value	1.25267e-09 (rank : 22)	NC score	0.500260 (rank : 22)
Query Neighborhood Hits	95	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
θ value	2.61198e-07 (rank : 23)	NC score	0.480490 (rank : 23)
Query Neighborhood Hits	95	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

CIC_HUMAN
θ value	0.00390308 (rank : 24)	NC score	0.044767 (rank : 28)
Query Neighborhood Hits	95	Target Neighborhood Hits	992	Shared Neighborhood Hits	44
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

T22D4_HUMAN
θ value	0.0148317 (rank : 25)	NC score	0.037338 (rank : 32)
Query Neighborhood Hits	95	Target Neighborhood Hits	403	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

DMRTD_HUMAN
θ value	0.0193708 (rank : 26)	NC score	0.045177 (rank : 27)
Query Neighborhood Hits	95	Target Neighborhood Hits	216	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

CK024_HUMAN
θ value	0.0431538 (rank : 27)	NC score	0.037997 (rank : 31)
Query Neighborhood Hits	95	Target Neighborhood Hits	408	Shared Neighborhood Hits	22
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

RGS3_MOUSE
θ value	0.0431538 (rank : 28)	NC score	0.027295 (rank : 40)
Query Neighborhood Hits	95	Target Neighborhood Hits	1621	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

3BP2_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.033953 (rank : 35)
Query Neighborhood Hits	95	Target Neighborhood Hits	296	Shared Neighborhood Hits	18
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

MAGE1_HUMAN
θ value	0.0736092 (rank : 30)	NC score	0.021616 (rank : 46)
Query Neighborhood Hits	95	Target Neighborhood Hits	1389	Shared Neighborhood Hits	46
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CEL_HUMAN
θ value	0.163984 (rank : 31)	NC score	0.017127 (rank : 57)
Query Neighborhood Hits	95	Target Neighborhood Hits	896	Shared Neighborhood Hits	33
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EGR4_HUMAN
θ value	0.21417 (rank : 32)	NC score	0.002130 (rank : 93)
Query Neighborhood Hits	95	Target Neighborhood Hits	939	Shared Neighborhood Hits	17
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

NCOA6_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.026913 (rank : 41)
Query Neighborhood Hits	95	Target Neighborhood Hits	1202	Shared Neighborhood Hits	33
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

YLPM1_HUMAN
θ value	0.21417 (rank : 34)	NC score	0.038909 (rank : 29)
Query Neighborhood Hits	95	Target Neighborhood Hits	670	Shared Neighborhood Hits	39
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CP007_MOUSE
θ value	0.279714 (rank : 35)	NC score	0.026782 (rank : 42)
Query Neighborhood Hits	95	Target Neighborhood Hits	231	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

RGS3_HUMAN
θ value	0.279714 (rank : 36)	NC score	0.022975 (rank : 45)
Query Neighborhood Hits	95	Target Neighborhood Hits	1375	Shared Neighborhood Hits	38
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PCLO_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.021166 (rank : 48)
Query Neighborhood Hits	95	Target Neighborhood Hits	2046	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

MLL3_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.018017 (rank : 55)
Query Neighborhood Hits	95	Target Neighborhood Hits	1644	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PSL1_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.020299 (rank : 51)
Query Neighborhood Hits	95	Target Neighborhood Hits	650	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

SON_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.023020 (rank : 44)
Query Neighborhood Hits	95	Target Neighborhood Hits	1568	Shared Neighborhood Hits	46
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ST1C2_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.038891 (rank : 30)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	O75897, Q53S63	Gene names	SULT1C2
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-) (SULT1C) (SULT1C#2).

BCOR_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.013484 (rank : 71)
Query Neighborhood Hits	95	Target Neighborhood Hits	609	Shared Neighborhood Hits	9
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

RALY_HUMAN
θ value	0.813845 (rank : 43)	NC score	0.014902 (rank : 65)
Query Neighborhood Hits	95	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKM9, Q14621, Q5QPL8, Q9BQX6, Q9UJE3	Gene names	RALY, P542
Domain Architecture
Description	RNA-binding protein Raly (hnRNP associated with lethal yellow homolog) (Autoantigen p542).

RPGF1_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.014830 (rank : 66)
Query Neighborhood Hits	95	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

SSH2_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.010471 (rank : 78)
Query Neighborhood Hits	95	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

CBP_MOUSE
θ value	1.06291 (rank : 46)	NC score	0.021140 (rank : 49)
Query Neighborhood Hits	95	Target Neighborhood Hits	1051	Shared Neighborhood Hits	40
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CHST2_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.048076 (rank : 25)
Query Neighborhood Hits	95	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4C5, Q9GZN5, Q9UED5, Q9Y6F2	Gene names	CHST2, GN6ST
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 2 (EC 2.8.2.-) (N-acetylglucosamine 6-O- sulfotransferase 1) (GlcNAc6ST-1) (Gn6ST) (Galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2) (GST-2).

CHST2_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.047697 (rank : 26)
Query Neighborhood Hits	95	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q80WV3, O88276, Q794G9	Gene names	Chst2, Gst2
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 2 (EC 2.8.2.-) (N-acetylglucosamine 6-O- sulfotransferase 1) (GlcNAc6ST-1) (Gn6st-1) (Galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2) (GST-2).

IF4B_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.021252 (rank : 47)
Query Neighborhood Hits	95	Target Neighborhood Hits	417	Shared Neighborhood Hits	13
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

K1543_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.024982 (rank : 43)
Query Neighborhood Hits	95	Target Neighborhood Hits	435	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

BAT2_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.036413 (rank : 33)
Query Neighborhood Hits	95	Target Neighborhood Hits	931	Shared Neighborhood Hits	45
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GSH2_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.002198 (rank : 92)
Query Neighborhood Hits	95	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZM3	Gene names	GSH2
Domain Architecture
Description	Homeobox protein GSH-2.

MKL1_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.016301 (rank : 60)
Query Neighborhood Hits	95	Target Neighborhood Hits	667	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

PER3_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.015305 (rank : 62)
Query Neighborhood Hits	95	Target Neighborhood Hits	479	Shared Neighborhood Hits	24
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

BCL9_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.018452 (rank : 53)
Query Neighborhood Hits	95	Target Neighborhood Hits	1008	Shared Neighborhood Hits	40
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCOR_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.012419 (rank : 74)
Query Neighborhood Hits	95	Target Neighborhood Hits	521	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CCD45_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.006635 (rank : 85)
Query Neighborhood Hits	95	Target Neighborhood Hits	663	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CD2_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.015126 (rank : 63)
Query Neighborhood Hits	95	Target Neighborhood Hits	504	Shared Neighborhood Hits	16
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

CIC_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.034427 (rank : 34)
Query Neighborhood Hits	95	Target Neighborhood Hits	742	Shared Neighborhood Hits	44
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ST1A3_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.028058 (rank : 39)
Query Neighborhood Hits	95	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	P50224, O95603, Q6ZWJ5	Gene names	SULT1A3, STM
Domain Architecture
Description	Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Aryl sulfotransferase 1A3) (Sulfotransferase, monoamine-preferring) (M-PST) (Thermolabile phenol sulfotransferase) (TL-PST) (Placental estrogen sulfotransferase) (Catecholamine-sulfating phenol sulfotransferase) (HAST3).

BCAR1_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.013918 (rank : 69)
Query Neighborhood Hits	95	Target Neighborhood Hits	554	Shared Neighborhood Hits	26
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

PDLI7_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.004012 (rank : 90)
Query Neighborhood Hits	95	Target Neighborhood Hits	279	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

ATS14_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.004051 (rank : 89)
Query Neighborhood Hits	95	Target Neighborhood Hits	382	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

BAT2_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.033693 (rank : 36)
Query Neighborhood Hits	95	Target Neighborhood Hits	947	Shared Neighborhood Hits	48
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BTBD7_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.010137 (rank : 79)
Query Neighborhood Hits	95	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

DMRTD_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.029266 (rank : 37)
Query Neighborhood Hits	95	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

IL3RB_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.016866 (rank : 58)
Query Neighborhood Hits	95	Target Neighborhood Hits	163	Shared Neighborhood Hits	17
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

SC24C_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.015121 (rank : 64)
Query Neighborhood Hits	95	Target Neighborhood Hits	662	Shared Neighborhood Hits	24
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

ST1C1_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.017316 (rank : 56)
Query Neighborhood Hits	95	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	O00338	Gene names	SULT1C1
Domain Architecture
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (SULT1C#1) (ST1C2) (humSULTC2).

TCGAP_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.011328 (rank : 77)
Query Neighborhood Hits	95	Target Neighborhood Hits	872	Shared Neighborhood Hits	34
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

WDR22_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.005107 (rank : 87)
Query Neighborhood Hits	95	Target Neighborhood Hits	328	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

ZN385_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.012432 (rank : 73)
Query Neighborhood Hits	95	Target Neighborhood Hits	614	Shared Neighborhood Hits	18
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

FA47A_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.014572 (rank : 67)
Query Neighborhood Hits	95	Target Neighborhood Hits	451	Shared Neighborhood Hits	22
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

IF4B_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.018870 (rank : 52)
Query Neighborhood Hits	95	Target Neighborhood Hits	368	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

K1802_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.014177 (rank : 68)
Query Neighborhood Hits	95	Target Neighborhood Hits	1378	Shared Neighborhood Hits	43
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MLL3_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.015984 (rank : 61)
Query Neighborhood Hits	95	Target Neighborhood Hits	1399	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PRRT3_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.018054 (rank : 54)
Query Neighborhood Hits	95	Target Neighborhood Hits	998	Shared Neighborhood Hits	35
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TULP4_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.009157 (rank : 81)
Query Neighborhood Hits	95	Target Neighborhood Hits	426	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

ZEP2_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.001463 (rank : 94)
Query Neighborhood Hits	95	Target Neighborhood Hits	964	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

CRSP7_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.011828 (rank : 76)
Query Neighborhood Hits	95	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

K1802_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.012695 (rank : 72)
Query Neighborhood Hits	95	Target Neighborhood Hits	1596	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

O10J3_HUMAN
θ value	6.88961 (rank : 82)	NC score	-0.003677 (rank : 96)
Query Neighborhood Hits	95	Target Neighborhood Hits	706	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JRS4	Gene names	OR10J3
Domain Architecture	No domain graphic available
Description	Olfactory receptor 10J3.

PCLO_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.016586 (rank : 59)
Query Neighborhood Hits	95	Target Neighborhood Hits	2275	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SP5_HUMAN
θ value	6.88961 (rank : 84)	NC score	-0.002231 (rank : 95)
Query Neighborhood Hits	95	Target Neighborhood Hits	832	Shared Neighborhood Hits	13
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

TRM1_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.008510 (rank : 82)
Query Neighborhood Hits	95	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TX08, Q3TBY4	Gene names	Trmt1, D8Ertd812e
Domain Architecture	No domain graphic available
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

AP180_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.013783 (rank : 70)
Query Neighborhood Hits	95	Target Neighborhood Hits	194	Shared Neighborhood Hits	20
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

ATX7_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.012147 (rank : 75)
Query Neighborhood Hits	95	Target Neighborhood Hits	328	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

B4GT1_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.002769 (rank : 91)
Query Neighborhood Hits	95	Target Neighborhood Hits	168	Shared Neighborhood Hits	2
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

K1543_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.021019 (rank : 50)
Query Neighborhood Hits	95	Target Neighborhood Hits	497	Shared Neighborhood Hits	26
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MINT_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.009778 (rank : 80)
Query Neighborhood Hits	95	Target Neighborhood Hits	1514	Shared Neighborhood Hits	38
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NRX2A_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.004922 (rank : 88)
Query Neighborhood Hits	95	Target Neighborhood Hits	614	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.008401 (rank : 83)
Query Neighborhood Hits	95	Target Neighborhood Hits	481	Shared Neighborhood Hits	16
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

RKHD1_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.006445 (rank : 86)
Query Neighborhood Hits	95	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

SPON2_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.006726 (rank : 84)
Query Neighborhood Hits	95	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

ST1C3_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.029032 (rank : 38)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q6IMI6, Q6IMI5	Gene names	SULT1C3
Domain Architecture	No domain graphic available
Description	Putative sulfotransferase 1C3 (EC 2.8.2.-).

ST2B1_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.056308 (rank : 24)
Query Neighborhood Hits	95	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O35400, Q8K472, Q91V03	Gene names	Sult2b1, Sult2b
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Sulfotransferase 2B) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

Hits sorted by NC score

OST4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST3A_HUMAN
NC score	0.988578 (rank : 2)	θ value	4.92331e-123 (rank : 2)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST2_HUMAN
NC score	0.987221 (rank : 3)	θ value	2.06847e-121 (rank : 5)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST3B_HUMAN
NC score	0.987161 (rank : 4)	θ value	1.87085e-122 (rank : 3)
Query Neighborhood Hits	95	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST2_MOUSE
NC score	0.986981 (rank : 5)	θ value	1.58377e-121 (rank : 4)
Query Neighborhood Hits	95	Target Neighborhood Hits	48	Shared Neighborhood Hits	28
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST6_HUMAN
NC score	0.986969 (rank : 6)	θ value	1.02895e-112 (rank : 8)
Query Neighborhood Hits	95	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST6_MOUSE
NC score	0.986890 (rank : 7)	θ value	8.71062e-112 (rank : 9)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

OST3A_MOUSE
NC score	0.986785 (rank : 8)	θ value	2.36663e-117 (rank : 6)
Query Neighborhood Hits	95	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3B_MOUSE
NC score	0.986335 (rank : 9)	θ value	1.8752e-114 (rank : 7)
Query Neighborhood Hits	95	Target Neighborhood Hits	42	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST1_HUMAN
NC score	0.964150 (rank : 10)	θ value	9.1404e-61 (rank : 12)
Query Neighborhood Hits	95	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST1_MOUSE
NC score	0.964131 (rank : 11)	θ value	1.19377e-60 (rank : 13)
Query Neighborhood Hits	95	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

OST5_HUMAN
NC score	0.963539 (rank : 12)	θ value	1.2325e-65 (rank : 11)
Query Neighborhood Hits	95	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST5_MOUSE
NC score	0.963538 (rank : 13)	θ value	7.2256e-66 (rank : 10)
Query Neighborhood Hits	95	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

NDST3_HUMAN
NC score	0.760467 (rank : 14)	θ value	1.6813e-30 (rank : 14)
Query Neighborhood Hits	95	Target Neighborhood Hits	37	Shared Neighborhood Hits	25
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST4_HUMAN
NC score	0.758750 (rank : 15)	θ value	7.06379e-29 (rank : 15)
Query Neighborhood Hits	95	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST2_HUMAN
NC score	0.758491 (rank : 16)	θ value	4.57862e-28 (rank : 18)
Query Neighborhood Hits	95	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST4_MOUSE
NC score	0.756569 (rank : 17)	θ value	2.05525e-28 (rank : 17)
Query Neighborhood Hits	95	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST3_MOUSE
NC score	0.755446 (rank : 18)	θ value	1.2049e-28 (rank : 16)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST2_MOUSE
NC score	0.754720 (rank : 19)	θ value	3.87602e-27 (rank : 19)
Query Neighborhood Hits	95	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST1_HUMAN
NC score	0.743833 (rank : 20)	θ value	2.51237e-26 (rank : 20)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_MOUSE
NC score	0.743290 (rank : 21)	θ value	7.30988e-26 (rank : 21)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

ST4S6_MOUSE
NC score	0.500260 (rank : 22)	θ value	1.25267e-09 (rank : 22)
Query Neighborhood Hits	95	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
NC score	0.480490 (rank : 23)	θ value	2.61198e-07 (rank : 23)
Query Neighborhood Hits	95	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

ST2B1_MOUSE
NC score	0.056308 (rank : 24)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	95	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O35400, Q8K472, Q91V03	Gene names	Sult2b1, Sult2b
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Sulfotransferase 2B) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

CHST2_HUMAN
NC score	0.048076 (rank : 25)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	95	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4C5, Q9GZN5, Q9UED5, Q9Y6F2	Gene names	CHST2, GN6ST
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 2 (EC 2.8.2.-) (N-acetylglucosamine 6-O- sulfotransferase 1) (GlcNAc6ST-1) (Gn6ST) (Galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2) (GST-2).

CHST2_MOUSE
NC score	0.047697 (rank : 26)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	95	Target Neighborhood Hits	23	Shared Neighborhood Hits	8
SwissProt Accessions	Q80WV3, O88276, Q794G9	Gene names	Chst2, Gst2
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 2 (EC 2.8.2.-) (N-acetylglucosamine 6-O- sulfotransferase 1) (GlcNAc6ST-1) (Gn6st-1) (Galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2) (GST-2).

DMRTD_HUMAN
NC score	0.045177 (rank : 27)	θ value	0.0193708 (rank : 26)
Query Neighborhood Hits	95	Target Neighborhood Hits	216	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

CIC_HUMAN
NC score	0.044767 (rank : 28)	θ value	0.00390308 (rank : 24)
Query Neighborhood Hits	95	Target Neighborhood Hits	992	Shared Neighborhood Hits	44
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

YLPM1_HUMAN
NC score	0.038909 (rank : 29)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	95	Target Neighborhood Hits	670	Shared Neighborhood Hits	39
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

ST1C2_HUMAN
NC score	0.038891 (rank : 30)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	O75897, Q53S63	Gene names	SULT1C2
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-) (SULT1C) (SULT1C#2).

CK024_HUMAN
NC score	0.037997 (rank : 31)	θ value	0.0431538 (rank : 27)
Query Neighborhood Hits	95	Target Neighborhood Hits	408	Shared Neighborhood Hits	22
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

T22D4_HUMAN
NC score	0.037338 (rank : 32)	θ value	0.0148317 (rank : 25)
Query Neighborhood Hits	95	Target Neighborhood Hits	403	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

BAT2_HUMAN
NC score	0.036413 (rank : 33)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	95	Target Neighborhood Hits	931	Shared Neighborhood Hits	45
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CIC_MOUSE
NC score	0.034427 (rank : 34)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	95	Target Neighborhood Hits	742	Shared Neighborhood Hits	44
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

3BP2_HUMAN
NC score	0.033953 (rank : 35)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	95	Target Neighborhood Hits	296	Shared Neighborhood Hits	18
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

BAT2_MOUSE
NC score	0.033693 (rank : 36)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	95	Target Neighborhood Hits	947	Shared Neighborhood Hits	48
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DMRTD_MOUSE
NC score	0.029266 (rank : 37)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	95	Target Neighborhood Hits	72	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGW9	Gene names	Dmrtc2, Dmrt7
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2 (Doublesex- and mab-3-related transcription factor 7).

ST1C3_HUMAN
NC score	0.029032 (rank : 38)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	95	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	Q6IMI6, Q6IMI5	Gene names	SULT1C3
Domain Architecture	No domain graphic available
Description	Putative sulfotransferase 1C3 (EC 2.8.2.-).

ST1A3_HUMAN
NC score	0.028058 (rank : 39)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	95	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	P50224, O95603, Q6ZWJ5	Gene names	SULT1A3, STM
Domain Architecture
Description	Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Aryl sulfotransferase 1A3) (Sulfotransferase, monoamine-preferring) (M-PST) (Thermolabile phenol sulfotransferase) (TL-PST) (Placental estrogen sulfotransferase) (Catecholamine-sulfating phenol sulfotransferase) (HAST3).

RGS3_MOUSE
NC score	0.027295 (rank : 40)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	95	Target Neighborhood Hits	1621	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NCOA6_HUMAN
NC score	0.026913 (rank : 41)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	95	Target Neighborhood Hits	1202	Shared Neighborhood Hits	33
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CP007_MOUSE
NC score	0.026782 (rank : 42)	θ value	0.279714 (rank : 35)
Query Neighborhood Hits	95	Target Neighborhood Hits	231	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

K1543_HUMAN
NC score	0.024982 (rank : 43)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	95	Target Neighborhood Hits	435	Shared Neighborhood Hits	24
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

SON_HUMAN
NC score	0.023020 (rank : 44)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	95	Target Neighborhood Hits	1568	Shared Neighborhood Hits	46
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

RGS3_HUMAN
NC score	0.022975 (rank : 45)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	95	Target Neighborhood Hits	1375	Shared Neighborhood Hits	38
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MAGE1_HUMAN
NC score	0.021616 (rank : 46)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	95	Target Neighborhood Hits	1389	Shared Neighborhood Hits	46
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

IF4B_HUMAN
NC score	0.021252 (rank : 47)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	95	Target Neighborhood Hits	417	Shared Neighborhood Hits	13
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

PCLO_HUMAN
NC score	0.021166 (rank : 48)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	95	Target Neighborhood Hits	2046	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CBP_MOUSE
NC score	0.021140 (rank : 49)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	95	Target Neighborhood Hits	1051	Shared Neighborhood Hits	40
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

K1543_MOUSE
NC score	0.021019 (rank : 50)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	95	Target Neighborhood Hits	497	Shared Neighborhood Hits	26
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PSL1_HUMAN
NC score	0.020299 (rank : 51)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	95	Target Neighborhood Hits	650	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

IF4B_MOUSE
NC score	0.018870 (rank : 52)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	95	Target Neighborhood Hits	368	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

BCL9_HUMAN
NC score	0.018452 (rank : 53)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	95	Target Neighborhood Hits	1008	Shared Neighborhood Hits	40
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

PRRT3_HUMAN
NC score	0.018054 (rank : 54)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	95	Target Neighborhood Hits	998	Shared Neighborhood Hits	35
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

MLL3_HUMAN
NC score	0.018017 (rank : 55)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	95	Target Neighborhood Hits	1644	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

ST1C1_HUMAN
NC score	0.017316 (rank : 56)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	95	Target Neighborhood Hits	27	Shared Neighborhood Hits	7
SwissProt Accessions	O00338	Gene names	SULT1C1
Domain Architecture
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (SULT1C#1) (ST1C2) (humSULTC2).

CEL_HUMAN
NC score	0.017127 (rank : 57)	θ value	0.163984 (rank : 31)
Query Neighborhood Hits	95	Target Neighborhood Hits	896	Shared Neighborhood Hits	33
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

IL3RB_HUMAN
NC score	0.016866 (rank : 58)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	95	Target Neighborhood Hits	163	Shared Neighborhood Hits	17
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

PCLO_MOUSE
NC score	0.016586 (rank : 59)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	95	Target Neighborhood Hits	2275	Shared Neighborhood Hits	52
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MKL1_MOUSE
NC score	0.016301 (rank : 60)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	95	Target Neighborhood Hits	667	Shared Neighborhood Hits	26
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MLL3_MOUSE
NC score	0.015984 (rank : 61)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	95	Target Neighborhood Hits	1399	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PER3_HUMAN
NC score	0.015305 (rank : 62)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	95	Target Neighborhood Hits	479	Shared Neighborhood Hits	24
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

CD2_HUMAN
NC score	0.015126 (rank : 63)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	95	Target Neighborhood Hits	504	Shared Neighborhood Hits	16
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

SC24C_HUMAN
NC score	0.015121 (rank : 64)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	95	Target Neighborhood Hits	662	Shared Neighborhood Hits	24
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

RALY_HUMAN
NC score	0.014902 (rank : 65)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	95	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKM9, Q14621, Q5QPL8, Q9BQX6, Q9UJE3	Gene names	RALY, P542
Domain Architecture
Description	RNA-binding protein Raly (hnRNP associated with lethal yellow homolog) (Autoantigen p542).

RPGF1_HUMAN
NC score	0.014830 (rank : 66)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	95	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

FA47A_HUMAN
NC score	0.014572 (rank : 67)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	95	Target Neighborhood Hits	451	Shared Neighborhood Hits	22
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

K1802_HUMAN
NC score	0.014177 (rank : 68)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	95	Target Neighborhood Hits	1378	Shared Neighborhood Hits	43
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

BCAR1_HUMAN
NC score	0.013918 (rank : 69)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	95	Target Neighborhood Hits	554	Shared Neighborhood Hits	26
SwissProt Accessions	P56945	Gene names	BCAR1, CAS, CRKAS
Domain Architecture
Description	Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas).

AP180_MOUSE
NC score	0.013783 (rank : 70)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	95	Target Neighborhood Hits	194	Shared Neighborhood Hits	20
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

BCOR_HUMAN
NC score	0.013484 (rank : 71)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	95	Target Neighborhood Hits	609	Shared Neighborhood Hits	9
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

K1802_MOUSE
NC score	0.012695 (rank : 72)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	95	Target Neighborhood Hits	1596	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ZN385_HUMAN
NC score	0.012432 (rank : 73)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	95	Target Neighborhood Hits	614	Shared Neighborhood Hits	18
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

BCOR_MOUSE
NC score	0.012419 (rank : 74)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	95	Target Neighborhood Hits	521	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ATX7_MOUSE
NC score	0.012147 (rank : 75)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	95	Target Neighborhood Hits	328	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CRSP7_HUMAN
NC score	0.011828 (rank : 76)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	95	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

TCGAP_HUMAN
NC score	0.011328 (rank : 77)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	95	Target Neighborhood Hits	872	Shared Neighborhood Hits	34
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

SSH2_MOUSE
NC score	0.010471 (rank : 78)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	95	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

BTBD7_MOUSE
NC score	0.010137 (rank : 79)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	95	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CFE5, Q80TC3, Q8BZY9	Gene names	Btbd7, Kiaa1525
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 7.

MINT_MOUSE
NC score	0.009778 (rank : 80)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	95	Target Neighborhood Hits	1514	Shared Neighborhood Hits	38
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TULP4_HUMAN
NC score	0.009157 (rank : 81)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	95	Target Neighborhood Hits	426	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

TRM1_MOUSE
NC score	0.008510 (rank : 82)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	95	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q3TX08, Q3TBY4	Gene names	Trmt1, D8Ertd812e
Domain Architecture	No domain graphic available
Description	N(2),N(2)-dimethylguanosine tRNA methyltransferase (EC 2.1.1.32) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA 2,2- dimethylguanosine-26 methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase).

NRX2B_HUMAN
NC score	0.008401 (rank : 83)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	95	Target Neighborhood Hits	481	Shared Neighborhood Hits	16
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SPON2_MOUSE
NC score	0.006726 (rank : 84)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	95	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BMS2, Q6SJD8	Gene names	Spon2
Domain Architecture	No domain graphic available
Description	Spondin-2 precursor (Mindin).

CCD45_MOUSE
NC score	0.006635 (rank : 85)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	95	Target Neighborhood Hits	663	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

RKHD1_HUMAN
NC score	0.006445 (rank : 86)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	95	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XN8	Gene names	RKHD1, KIAA2031
Domain Architecture
Description	RING finger and KH domain-containing protein 1.

WDR22_HUMAN
NC score	0.005107 (rank : 87)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	95	Target Neighborhood Hits	328	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JK2, O60559, Q8N3V3, Q8N3V5	Gene names	WDR22, BCRG2, KIAA1824
Domain Architecture
Description	WD repeat protein 22 (Breakpoint cluster region protein 2) (BCRP2).

NRX2A_HUMAN
NC score	0.004922 (rank : 88)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	95	Target Neighborhood Hits	614	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

ATS14_HUMAN
NC score	0.004051 (rank : 89)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	95	Target Neighborhood Hits	382	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

PDLI7_MOUSE
NC score	0.004012 (rank : 90)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	95	Target Neighborhood Hits	279	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

B4GT1_HUMAN
NC score	0.002769 (rank : 91)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	95	Target Neighborhood Hits	168	Shared Neighborhood Hits	2
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

GSH2_HUMAN
NC score	0.002198 (rank : 92)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	95	Target Neighborhood Hits	324	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZM3	Gene names	GSH2
Domain Architecture
Description	Homeobox protein GSH-2.

EGR4_HUMAN
NC score	0.002130 (rank : 93)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	95	Target Neighborhood Hits	939	Shared Neighborhood Hits	17
SwissProt Accessions	Q05215	Gene names	EGR4
Domain Architecture
Description	Early growth response protein 4 (EGR-4) (AT133).

ZEP2_MOUSE
NC score	0.001463 (rank : 94)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	95	Target Neighborhood Hits	964	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

SP5_HUMAN
NC score	-0.002231 (rank : 95)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	95	Target Neighborhood Hits	832	Shared Neighborhood Hits	13
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

O10J3_HUMAN
NC score	-0.003677 (rank : 96)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	95	Target Neighborhood Hits	706	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JRS4	Gene names	OR10J3
Domain Architecture	No domain graphic available
Description	Olfactory receptor 10J3.