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Network neighborhood for query Sequence : OST2_HUMAN

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OST2_HUMAN
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OST2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST2_MOUSE
θ value	1.60882e-182 (rank : 2)	NC score	0.998354 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST4_HUMAN
θ value	2.06847e-121 (rank : 3)	NC score	0.987221 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST3A_HUMAN
θ value	1.81207e-117 (rank : 4)	NC score	0.994465 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST3B_HUMAN
θ value	1.81207e-117 (rank : 5)	NC score	0.992903 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST3B_MOUSE
θ value	1.09934e-114 (rank : 6)	NC score	0.992075 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	42	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST3A_MOUSE
θ value	1.58745e-113 (rank : 7)	NC score	0.992298 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST6_MOUSE
θ value	5.28454e-109 (rank : 8)	NC score	0.992938 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

OST6_HUMAN
θ value	7.63087e-108 (rank : 9)	NC score	0.992775 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST5_HUMAN
θ value	6.11685e-65 (rank : 10)	NC score	0.971376 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST5_MOUSE
θ value	2.32439e-64 (rank : 11)	NC score	0.971220 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

OST1_HUMAN
θ value	6.99855e-61 (rank : 12)	NC score	0.971541 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST1_MOUSE
θ value	2.65945e-60 (rank : 13)	NC score	0.971097 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

NDST3_HUMAN
θ value	6.38894e-30 (rank : 14)	NC score	0.765545 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST2_HUMAN
θ value	1.85889e-29 (rank : 15)	NC score	0.762825 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST4_HUMAN
θ value	4.14116e-29 (rank : 16)	NC score	0.762284 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST3_MOUSE
θ value	5.40856e-29 (rank : 17)	NC score	0.760716 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST2_MOUSE
θ value	2.27234e-27 (rank : 18)	NC score	0.759346 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST4_MOUSE
θ value	2.96777e-27 (rank : 19)	NC score	0.759795 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST1_HUMAN
θ value	4.28545e-26 (rank : 20)	NC score	0.749144 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_MOUSE
θ value	1.24688e-25 (rank : 21)	NC score	0.748634 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

ST4S6_MOUSE
θ value	0.000602161 (rank : 22)	NC score	0.461558 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
θ value	0.00298849 (rank : 23)	NC score	0.442209 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

ST6B1_HUMAN
θ value	0.21417 (rank : 24)	NC score	0.041432 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q6IMI4	Gene names	SULT6B1
Domain Architecture	No domain graphic available
Description	Sulfotransferase 6B1 (EC 2.8.2.-).

ABCA2_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.019810 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

AT11B_HUMAN
θ value	0.365318 (rank : 26)	NC score	0.011931 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2G3, Q96FN1, Q9UKK7	Gene names	ATP11B, ATPIF, ATPIR, KIAA0956
Domain Architecture
Description	Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase class I type 11B) (ATPase IR).

ABCA2_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.017017 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ST2B1_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.058536 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O35400, Q8K472, Q91V03	Gene names	Sult2b1, Sult2b
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Sulfotransferase 2B) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

MRP4_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.005129 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

NMT1_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.010507 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P30419, Q9UE09	Gene names	NMT1, NMT
Domain Architecture
Description	Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Peptide N- myristoyltransferase 1) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase).

ST1A3_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.026278 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	P50224, O95603, Q6ZWJ5	Gene names	SULT1A3, STM
Domain Architecture
Description	Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Aryl sulfotransferase 1A3) (Sulfotransferase, monoamine-preferring) (M-PST) (Thermolabile phenol sulfotransferase) (TL-PST) (Placental estrogen sulfotransferase) (Catecholamine-sulfating phenol sulfotransferase) (HAST3).

ST2B1_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.050471 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	57	Shared Neighborhood Hits	12
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

RNF17_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.006055 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

SPR1A_MOUSE
θ value	8.99809 (rank : 34)	NC score	0.006209 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	343	Shared Neighborhood Hits	3
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

Hits sorted by NC score

OST2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST2_MOUSE
NC score	0.998354 (rank : 2)	θ value	1.60882e-182 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST3A_HUMAN
NC score	0.994465 (rank : 3)	θ value	1.81207e-117 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST6_MOUSE
NC score	0.992938 (rank : 4)	θ value	5.28454e-109 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

OST3B_HUMAN
NC score	0.992903 (rank : 5)	θ value	1.81207e-117 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST6_HUMAN
NC score	0.992775 (rank : 6)	θ value	7.63087e-108 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST3A_MOUSE
NC score	0.992298 (rank : 7)	θ value	1.58745e-113 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3B_MOUSE
NC score	0.992075 (rank : 8)	θ value	1.09934e-114 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	42	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST4_HUMAN
NC score	0.987221 (rank : 9)	θ value	2.06847e-121 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST1_HUMAN
NC score	0.971541 (rank : 10)	θ value	6.99855e-61 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST5_HUMAN
NC score	0.971376 (rank : 11)	θ value	6.11685e-65 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST5_MOUSE
NC score	0.971220 (rank : 12)	θ value	2.32439e-64 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

OST1_MOUSE
NC score	0.971097 (rank : 13)	θ value	2.65945e-60 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

NDST3_HUMAN
NC score	0.765545 (rank : 14)	θ value	6.38894e-30 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST2_HUMAN
NC score	0.762825 (rank : 15)	θ value	1.85889e-29 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST4_HUMAN
NC score	0.762284 (rank : 16)	θ value	4.14116e-29 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST3_MOUSE
NC score	0.760716 (rank : 17)	θ value	5.40856e-29 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST4_MOUSE
NC score	0.759795 (rank : 18)	θ value	2.96777e-27 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST2_MOUSE
NC score	0.759346 (rank : 19)	θ value	2.27234e-27 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST1_HUMAN
NC score	0.749144 (rank : 20)	θ value	4.28545e-26 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_MOUSE
NC score	0.748634 (rank : 21)	θ value	1.24688e-25 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

ST4S6_MOUSE
NC score	0.461558 (rank : 22)	θ value	0.000602161 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
NC score	0.442209 (rank : 23)	θ value	0.00298849 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

ST2B1_MOUSE
NC score	0.058536 (rank : 24)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O35400, Q8K472, Q91V03	Gene names	Sult2b1, Sult2b
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Sulfotransferase 2B) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

ST2B1_HUMAN
NC score	0.050471 (rank : 25)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	57	Shared Neighborhood Hits	12
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

ST6B1_HUMAN
NC score	0.041432 (rank : 26)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q6IMI4	Gene names	SULT6B1
Domain Architecture	No domain graphic available
Description	Sulfotransferase 6B1 (EC 2.8.2.-).

ST1A3_HUMAN
NC score	0.026278 (rank : 27)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	14
SwissProt Accessions	P50224, O95603, Q6ZWJ5	Gene names	SULT1A3, STM
Domain Architecture
Description	Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Aryl sulfotransferase 1A3) (Sulfotransferase, monoamine-preferring) (M-PST) (Thermolabile phenol sulfotransferase) (TL-PST) (Placental estrogen sulfotransferase) (Catecholamine-sulfating phenol sulfotransferase) (HAST3).

ABCA2_HUMAN
NC score	0.019810 (rank : 28)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	143	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA2_MOUSE
NC score	0.017017 (rank : 29)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

AT11B_HUMAN
NC score	0.011931 (rank : 30)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	71	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2G3, Q96FN1, Q9UKK7	Gene names	ATP11B, ATPIF, ATPIR, KIAA0956
Domain Architecture
Description	Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase class I type 11B) (ATPase IR).

NMT1_HUMAN
NC score	0.010507 (rank : 31)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P30419, Q9UE09	Gene names	NMT1, NMT
Domain Architecture
Description	Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Peptide N- myristoyltransferase 1) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase).

SPR1A_MOUSE
NC score	0.006209 (rank : 32)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	343	Shared Neighborhood Hits	3
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

RNF17_MOUSE
NC score	0.006055 (rank : 33)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q99MV7	Gene names	Rnf17
Domain Architecture
Description	RING finger protein 17.

MRP4_HUMAN
NC score	0.005129 (rank : 34)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).