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Network neighborhood for query Sequence : OST3A_HUMAN

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OST3A_HUMAN
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OST3A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST3A_MOUSE
θ value	2.11585e-158 (rank : 2)	NC score	0.997777 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3B_HUMAN
θ value	1.46868e-151 (rank : 3)	NC score	0.997791 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST3B_MOUSE
θ value	1.86219e-138 (rank : 4)	NC score	0.996896 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST4_HUMAN
θ value	4.92331e-123 (rank : 5)	NC score	0.988578 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST6_HUMAN
θ value	7.35691e-119 (rank : 6)	NC score	0.995857 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST2_HUMAN
θ value	1.81207e-117 (rank : 7)	NC score	0.994465 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST6_MOUSE
θ value	3.09092e-117 (rank : 8)	NC score	0.995673 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

OST2_MOUSE
θ value	4.03687e-117 (rank : 9)	NC score	0.993755 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST5_HUMAN
θ value	1.36269e-64 (rank : 10)	NC score	0.968834 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST5_MOUSE
θ value	1.36269e-64 (rank : 11)	NC score	0.968797 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

OST1_HUMAN
θ value	6.55044e-59 (rank : 12)	NC score	0.968866 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST1_MOUSE
θ value	1.23536e-57 (rank : 13)	NC score	0.968734 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

NDST3_HUMAN
θ value	1.85889e-29 (rank : 14)	NC score	0.761917 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST4_MOUSE
θ value	1.2049e-28 (rank : 15)	NC score	0.757737 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST3_MOUSE
θ value	1.57365e-28 (rank : 16)	NC score	0.757090 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST4_HUMAN
θ value	3.50572e-28 (rank : 17)	NC score	0.759725 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST2_HUMAN
θ value	1.33217e-27 (rank : 18)	NC score	0.759137 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST2_MOUSE
θ value	1.73987e-27 (rank : 19)	NC score	0.756165 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST1_HUMAN
θ value	5.06226e-27 (rank : 20)	NC score	0.745821 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_MOUSE
θ value	1.92365e-26 (rank : 21)	NC score	0.745245 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

ST4S6_MOUSE
θ value	7.59969e-07 (rank : 22)	NC score	0.490063 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
θ value	1.69304e-06 (rank : 23)	NC score	0.471208 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

CHST7_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.048474 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NS84, O75667	Gene names	CHST7
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 7 (EC 2.8.2.17) (EC 2.8.2.-) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (N-acetylglucosamine 6-O- sulfotransferase 1) (GlcNAc6ST-4) (Galactose/N-acetylglucosamine/N- acetylglucosamine 6-O-sulfotransferase 5) (GST-5).

ST1C2_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.041843 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	O75897, Q53S63	Gene names	SULT1C2
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-) (SULT1C) (SULT1C#2).

ST2B1_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.064334 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O35400, Q8K472, Q91V03	Gene names	Sult2b1, Sult2b
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Sulfotransferase 2B) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

CHST7_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.046039 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EP78, Q99NB0	Gene names	Chst7, Gst5
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 7 (EC 2.8.2.17) (EC 2.8.2.-) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (mC6ST-2) (N- acetylglucosamine 6-O-sulfotransferase 1) (GlcNAc6ST-4) (Galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5) (GST-5).

ST2B1_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.056260 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	57	Shared Neighborhood Hits	12
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

ADA1B_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.002121 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	978	Shared Neighborhood Hits	3
SwissProt Accessions	P35368	Gene names	ADRA1B
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).

TAP1_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.005558 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

PAF49_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.007848 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

ST1A1_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.014775 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	P52840	Gene names	Sult1a1, St1a1, Stp, Stp1
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1A1 (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Sulfokinase) (Phenol/aryl sulfotransferase) (mSTp1) (ST1A4).

BACE1_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.004609 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P56817, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5	Gene names	BACE1, BACE
Domain Architecture
Description	Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).

CXB4_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.001881 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NTQ9	Gene names	GJB4
Domain Architecture
Description	Gap junction beta-4 protein (Connexin-30.3) (Cx30.3).

Hits sorted by NC score

OST3A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST3B_HUMAN
NC score	0.997791 (rank : 2)	θ value	1.46868e-151 (rank : 3)
Query Neighborhood Hits	34	Target Neighborhood Hits	51	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST3A_MOUSE
NC score	0.997777 (rank : 3)	θ value	2.11585e-158 (rank : 2)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3B_MOUSE
NC score	0.996896 (rank : 4)	θ value	1.86219e-138 (rank : 4)
Query Neighborhood Hits	34	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST6_HUMAN
NC score	0.995857 (rank : 5)	θ value	7.35691e-119 (rank : 6)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	27
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST6_MOUSE
NC score	0.995673 (rank : 6)	θ value	3.09092e-117 (rank : 8)
Query Neighborhood Hits	34	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

OST2_HUMAN
NC score	0.994465 (rank : 7)	θ value	1.81207e-117 (rank : 7)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST2_MOUSE
NC score	0.993755 (rank : 8)	θ value	4.03687e-117 (rank : 9)
Query Neighborhood Hits	34	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST4_HUMAN
NC score	0.988578 (rank : 9)	θ value	4.92331e-123 (rank : 5)
Query Neighborhood Hits	34	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST1_HUMAN
NC score	0.968866 (rank : 10)	θ value	6.55044e-59 (rank : 12)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST5_HUMAN
NC score	0.968834 (rank : 11)	θ value	1.36269e-64 (rank : 10)
Query Neighborhood Hits	34	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST5_MOUSE
NC score	0.968797 (rank : 12)	θ value	1.36269e-64 (rank : 11)
Query Neighborhood Hits	34	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

OST1_MOUSE
NC score	0.968734 (rank : 13)	θ value	1.23536e-57 (rank : 13)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

NDST3_HUMAN
NC score	0.761917 (rank : 14)	θ value	1.85889e-29 (rank : 14)
Query Neighborhood Hits	34	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST4_HUMAN
NC score	0.759725 (rank : 15)	θ value	3.50572e-28 (rank : 17)
Query Neighborhood Hits	34	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST2_HUMAN
NC score	0.759137 (rank : 16)	θ value	1.33217e-27 (rank : 18)
Query Neighborhood Hits	34	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST4_MOUSE
NC score	0.757737 (rank : 17)	θ value	1.2049e-28 (rank : 15)
Query Neighborhood Hits	34	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST3_MOUSE
NC score	0.757090 (rank : 18)	θ value	1.57365e-28 (rank : 16)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST2_MOUSE
NC score	0.756165 (rank : 19)	θ value	1.73987e-27 (rank : 19)
Query Neighborhood Hits	34	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST1_HUMAN
NC score	0.745821 (rank : 20)	θ value	5.06226e-27 (rank : 20)
Query Neighborhood Hits	34	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_MOUSE
NC score	0.745245 (rank : 21)	θ value	1.92365e-26 (rank : 21)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

ST4S6_MOUSE
NC score	0.490063 (rank : 22)	θ value	7.59969e-07 (rank : 22)
Query Neighborhood Hits	34	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
NC score	0.471208 (rank : 23)	θ value	1.69304e-06 (rank : 23)
Query Neighborhood Hits	34	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

ST2B1_MOUSE
NC score	0.064334 (rank : 24)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	34	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	O35400, Q8K472, Q91V03	Gene names	Sult2b1, Sult2b
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Sulfotransferase 2B) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

ST2B1_HUMAN
NC score	0.056260 (rank : 25)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	34	Target Neighborhood Hits	57	Shared Neighborhood Hits	12
SwissProt Accessions	O00204, O00205, O75814	Gene names	SULT2B1, HSST2
Domain Architecture	No domain graphic available
Description	Sulfotransferase family cytosolic 2B member 1 (EC 2.8.2.2) (Sulfotransferase 2B1) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2).

CHST7_HUMAN
NC score	0.048474 (rank : 26)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	34	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NS84, O75667	Gene names	CHST7
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 7 (EC 2.8.2.17) (EC 2.8.2.-) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (N-acetylglucosamine 6-O- sulfotransferase 1) (GlcNAc6ST-4) (Galactose/N-acetylglucosamine/N- acetylglucosamine 6-O-sulfotransferase 5) (GST-5).

CHST7_MOUSE
NC score	0.046039 (rank : 27)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	34	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EP78, Q99NB0	Gene names	Chst7, Gst5
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 7 (EC 2.8.2.17) (EC 2.8.2.-) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (mC6ST-2) (N- acetylglucosamine 6-O-sulfotransferase 1) (GlcNAc6ST-4) (Galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5) (GST-5).

ST1C2_HUMAN
NC score	0.041843 (rank : 28)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	34	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	O75897, Q53S63	Gene names	SULT1C2
Domain Architecture
Description	Sulfotransferase 1C2 (EC 2.8.2.-) (SULT1C) (SULT1C#2).

ST1A1_MOUSE
NC score	0.014775 (rank : 29)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	34	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	P52840	Gene names	Sult1a1, St1a1, Stp, Stp1
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1A1 (EC 2.8.2.1) (Aryl sulfotransferase) (Phenol sulfotransferase) (Sulfokinase) (Phenol/aryl sulfotransferase) (mSTp1) (ST1A4).

PAF49_HUMAN
NC score	0.007848 (rank : 30)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	34	Target Neighborhood Hits	169	Shared Neighborhood Hits	2
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

TAP1_HUMAN
NC score	0.005558 (rank : 31)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	34	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

BACE1_HUMAN
NC score	0.004609 (rank : 32)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	34	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P56817, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5	Gene names	BACE1, BACE
Domain Architecture
Description	Beta-secretase 1 precursor (EC 3.4.23.46) (Beta-site APP cleaving enzyme 1) (Beta-site amyloid precursor protein cleaving enzyme 1) (Membrane-associated aspartic protease 2) (Memapsin-2) (Aspartyl protease 2) (Asp 2) (ASP2).

ADA1B_HUMAN
NC score	0.002121 (rank : 33)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	34	Target Neighborhood Hits	978	Shared Neighborhood Hits	3
SwissProt Accessions	P35368	Gene names	ADRA1B
Domain Architecture
Description	Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B- adrenoreceptor).

CXB4_HUMAN
NC score	0.001881 (rank : 34)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	34	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NTQ9	Gene names	GJB4
Domain Architecture
Description	Gap junction beta-4 protein (Connexin-30.3) (Cx30.3).