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Network neighborhood for query Sequence : NDST4_MOUSE

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NDST4_MOUSE
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NDST1_HUMAN
θ value	0 (rank : 1)	NC score	0.996803 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_MOUSE
θ value	0 (rank : 2)	NC score	0.996923 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	26
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST2_HUMAN
θ value	0 (rank : 3)	NC score	0.997075 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST2_MOUSE
θ value	0 (rank : 4)	NC score	0.997197 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST3_HUMAN
θ value	0 (rank : 5)	NC score	0.998559 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST3_MOUSE
θ value	0 (rank : 6)	NC score	0.998447 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST4_HUMAN
θ value	0 (rank : 7)	NC score	0.999709 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST4_MOUSE
θ value	0 (rank : 8)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

OST1_HUMAN
θ value	1.08979e-29 (rank : 9)	NC score	0.787352 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST3A_MOUSE
θ value	2.42779e-29 (rank : 10)	NC score	0.759578 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3B_MOUSE
θ value	2.42779e-29 (rank : 11)	NC score	0.757384 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST5_MOUSE
θ value	3.17079e-29 (rank : 12)	NC score	0.785778 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

OST5_HUMAN
θ value	4.14116e-29 (rank : 13)	NC score	0.785528 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST3A_HUMAN
θ value	1.2049e-28 (rank : 14)	NC score	0.757737 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST3B_HUMAN
θ value	1.2049e-28 (rank : 15)	NC score	0.755551 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST1_MOUSE
θ value	2.05525e-28 (rank : 16)	NC score	0.785482 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

OST4_HUMAN
θ value	2.05525e-28 (rank : 17)	NC score	0.756569 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	95	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST2_HUMAN
θ value	2.96777e-27 (rank : 18)	NC score	0.759795 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST2_MOUSE
θ value	6.61148e-27 (rank : 19)	NC score	0.760077 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST6_HUMAN
θ value	8.63488e-27 (rank : 20)	NC score	0.756237 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST6_MOUSE
θ value	8.63488e-27 (rank : 21)	NC score	0.753612 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

ST4S6_MOUSE
θ value	4.76016e-09 (rank : 22)	NC score	0.449684 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
θ value	3.08544e-08 (rank : 23)	NC score	0.439880 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

ST1C3_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.052729 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	Q6IMI6, Q6IMI5	Gene names	SULT1C3
Domain Architecture	No domain graphic available
Description	Putative sulfotransferase 1C3 (EC 2.8.2.-).

ERG_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.016239 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	P11308, Q16113	Gene names	ERG
Domain Architecture
Description	Transcriptional regulator ERG (Transforming protein ERG).

ST1A3_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.044172 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	P50224, O95603, Q6ZWJ5	Gene names	SULT1A3, STM
Domain Architecture
Description	Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Aryl sulfotransferase 1A3) (Sulfotransferase, monoamine-preferring) (M-PST) (Thermolabile phenol sulfotransferase) (TL-PST) (Placental estrogen sulfotransferase) (Catecholamine-sulfating phenol sulfotransferase) (HAST3).

ST4A1_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.036144 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BR01, O43728	Gene names	SULT4A1, SULTX3
Domain Architecture
Description	Sulfotransferase 4A1 (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST).

ERG_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.011464 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	P81270, Q8C5L4, Q920K7, Q920K8, Q920K9	Gene names	Erg, Erg-3
Domain Architecture
Description	Transcriptional regulator ERG.

MRP2_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.010198 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

ST2A1_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.015482 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	Q06520	Gene names	SULT2A1, HST, STD
Domain Architecture
Description	Bile salt sulfotransferase (EC 2.8.2.14) (Hydroxysteroid Sulfotransferase) (HST) (Dehydroepiandrosterone sulfotransferase) (DHEA-ST) (ST2) (ST2A3).

IL2RG_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.005859 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

MGR1_HUMAN
θ value	8.99809 (rank : 32)	NC score	0.006974 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

ST1C1_MOUSE
θ value	8.99809 (rank : 33)	NC score	0.021394 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	9
SwissProt Accessions	Q80VR3, O70262	Gene names	Sult1c1, Sult1a2
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (Phenol sulfotransferase).

Hits sorted by NC score

NDST4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST4_HUMAN
NC score	0.999709 (rank : 2)	θ value	0 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST3_HUMAN
NC score	0.998559 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST3_MOUSE
NC score	0.998447 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

NDST2_MOUSE
NC score	0.997197 (rank : 5)	θ value	0 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	P52850, Q3UDF4, Q549P5	Gene names	Ndst2, Hsst2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) (Mndns) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)].

NDST2_HUMAN
NC score	0.997075 (rank : 6)	θ value	0 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	26
SwissProt Accessions	P52849, Q2TB32, Q59H89	Gene names	NDST2, HSST2
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST- 2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 2 (EC 2.8.2.-)].

NDST1_MOUSE
NC score	0.996923 (rank : 7)	θ value	0 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	26
SwissProt Accessions	Q3UHN9, O70353, Q3TBX3, Q3TDS3, Q8BZE5, Q9R206	Gene names	Ndst1
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

NDST1_HUMAN
NC score	0.996803 (rank : 8)	θ value	0 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	P52848, Q96E57	Gene names	NDST1, HSST, HSST1
Domain Architecture
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST- 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) (N- heparan sulfate sulfotransferase 1) (N-HSST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 1 (EC 2.8.2.-)].

OST1_HUMAN
NC score	0.787352 (rank : 9)	θ value	1.08979e-29 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	O14792, Q6PEY8	Gene names	HS3ST1, 3OST, 3OST1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1).

OST5_MOUSE
NC score	0.785778 (rank : 10)	θ value	3.17079e-29 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	25	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BSL4	Gene names	Hs3st5, Hs3ost5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5).

OST5_HUMAN
NC score	0.785528 (rank : 11)	θ value	4.14116e-29 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	24	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZT8, Q52LI2, Q8N285	Gene names	HS3ST5, 3OST5, HS3OST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) (h3-OST-5).

OST1_MOUSE
NC score	0.785482 (rank : 12)	θ value	2.05525e-28 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	O35310	Gene names	Hs3st1, 3ost, 3ost1
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 1 precursor (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (Heparan sulfate 3-O-sulfotransferase 1).

OST2_MOUSE
NC score	0.760077 (rank : 13)	θ value	6.61148e-27 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q673U1, Q8BLP1, Q8C055	Gene names	Hs3st2, 3ost2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2).

OST2_HUMAN
NC score	0.759795 (rank : 14)	θ value	2.96777e-27 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y278	Gene names	HS3ST2, 3OST2
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2).

OST3A_MOUSE
NC score	0.759578 (rank : 15)	θ value	2.42779e-29 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BKN6	Gene names	Hs3st3a1, 3ost3a1, Hs3st3a
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1).

OST3A_HUMAN
NC score	0.757737 (rank : 16)	θ value	1.2049e-28 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y663	Gene names	HS3ST3A1, 3OST3A1, HS3ST3A
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A).

OST3B_MOUSE
NC score	0.757384 (rank : 17)	θ value	2.42779e-29 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	42	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QZS6	Gene names	Hs3st3b1, 3ost3b1, Hs3st3b
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B).

OST4_HUMAN
NC score	0.756569 (rank : 18)	θ value	2.05525e-28 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	95	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y661, Q5QI42, Q8NDC2	Gene names	HS3ST4, 3OST4
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4).

OST6_HUMAN
NC score	0.756237 (rank : 19)	θ value	8.63488e-27 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QI5, Q96RX7	Gene names	HS3ST6, HS3ST5
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6).

OST3B_HUMAN
NC score	0.755551 (rank : 20)	θ value	1.2049e-28 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y662	Gene names	HS3ST3B1, 3OST3B1, HS3ST3B
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B).

OST6_MOUSE
NC score	0.753612 (rank : 21)	θ value	8.63488e-27 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q5GFD5	Gene names	Hs3st6
Domain Architecture	No domain graphic available
Description	Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (Heparan sulfate 3-O-sulfotransferase 6) (3-OST-6).

ST4S6_MOUSE
NC score	0.449684 (rank : 22)	θ value	4.76016e-09 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q91XQ5, Q80TW4, Q8BLQ5, Q9D2N6	Gene names	Galnac4s6st, Brag, Kiaa0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein).

ST4S6_HUMAN
NC score	0.439880 (rank : 23)	θ value	3.08544e-08 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q7LFX5, O60338, O60474, Q86VM4	Gene names	GALNAC4S6ST, BRAG, KIAA0598
Domain Architecture	No domain graphic available
Description	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (EC 2.8.2.33) (GalNAc4S-6ST) (B-cell RAG-associated gene protein) (hBRAG).

ST1C3_HUMAN
NC score	0.052729 (rank : 24)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	Q6IMI6, Q6IMI5	Gene names	SULT1C3
Domain Architecture	No domain graphic available
Description	Putative sulfotransferase 1C3 (EC 2.8.2.-).

ST1A3_HUMAN
NC score	0.044172 (rank : 25)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	38	Shared Neighborhood Hits	15
SwissProt Accessions	P50224, O95603, Q6ZWJ5	Gene names	SULT1A3, STM
Domain Architecture
Description	Monoamine-sulfating phenol sulfotransferase (EC 2.8.2.1) (Aryl sulfotransferase 1A3) (Sulfotransferase, monoamine-preferring) (M-PST) (Thermolabile phenol sulfotransferase) (TL-PST) (Placental estrogen sulfotransferase) (Catecholamine-sulfating phenol sulfotransferase) (HAST3).

ST4A1_HUMAN
NC score	0.036144 (rank : 26)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BR01, O43728	Gene names	SULT4A1, SULTX3
Domain Architecture
Description	Sulfotransferase 4A1 (EC 2.8.2.-) (Brain sulfotransferase-like protein) (hBR-STL) (hBR-STL-1) (Nervous system sulfotransferase) (NST).

ST1C1_MOUSE
NC score	0.021394 (rank : 27)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	35	Shared Neighborhood Hits	9
SwissProt Accessions	Q80VR3, O70262	Gene names	Sult1c1, Sult1a2
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (Phenol sulfotransferase).

ERG_HUMAN
NC score	0.016239 (rank : 28)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	P11308, Q16113	Gene names	ERG
Domain Architecture
Description	Transcriptional regulator ERG (Transforming protein ERG).

ST2A1_HUMAN
NC score	0.015482 (rank : 29)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	7
SwissProt Accessions	Q06520	Gene names	SULT2A1, HST, STD
Domain Architecture
Description	Bile salt sulfotransferase (EC 2.8.2.14) (Hydroxysteroid Sulfotransferase) (HST) (Dehydroepiandrosterone sulfotransferase) (DHEA-ST) (ST2) (ST2A3).

ERG_MOUSE
NC score	0.011464 (rank : 30)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	P81270, Q8C5L4, Q920K7, Q920K8, Q920K9	Gene names	Erg, Erg-3
Domain Architecture
Description	Transcriptional regulator ERG.

MRP2_MOUSE
NC score	0.010198 (rank : 31)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

MGR1_HUMAN
NC score	0.006974 (rank : 32)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

IL2RG_HUMAN
NC score	0.005859 (rank : 33)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).