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Network neighborhood for query Sequence : MRP2_MOUSE

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MRP2_MOUSE
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ABCC9_HUMAN
θ value	0 (rank : 1)	NC score	0.977100 (rank : 15)
Query Neighborhood Hits	113	Target Neighborhood Hits	108	Shared Neighborhood Hits	90
SwissProt Accessions	O60706, O60707	Gene names	ABCC9, SUR2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

ABCC9_MOUSE
θ value	0 (rank : 2)	NC score	0.977241 (rank : 13)
Query Neighborhood Hits	113	Target Neighborhood Hits	110	Shared Neighborhood Hits	89
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

MRP1_HUMAN
θ value	0 (rank : 3)	NC score	0.993561 (rank : 3)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	90
SwissProt Accessions	P33527, O14819, O43333, P78419, Q59GI9, Q9UQ97, Q9UQ99, Q9UQA0	Gene names	ABCC1, MRP, MRP1
Domain Architecture
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP1_MOUSE
θ value	0 (rank : 4)	NC score	0.993435 (rank : 4)
Query Neighborhood Hits	113	Target Neighborhood Hits	110	Shared Neighborhood Hits	90
SwissProt Accessions	O35379	Gene names	Abcc1, Abcc1a, Abcc1b, Mdrap, Mrp
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP2_HUMAN
θ value	0 (rank : 5)	NC score	0.996578 (rank : 2)
Query Neighborhood Hits	113	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	Q92887, Q14022, Q92500, Q92798, Q99663, Q9UMS2	Gene names	ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein).

MRP2_MOUSE
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	113
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

MRP3_HUMAN
θ value	0 (rank : 7)	NC score	0.993174 (rank : 5)
Query Neighborhood Hits	113	Target Neighborhood Hits	125	Shared Neighborhood Hits	92
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

MRP4_HUMAN
θ value	0 (rank : 8)	NC score	0.987263 (rank : 8)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	90
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

MRP5_HUMAN
θ value	0 (rank : 9)	NC score	0.977699 (rank : 12)
Query Neighborhood Hits	113	Target Neighborhood Hits	110	Shared Neighborhood Hits	89
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

MRP5_MOUSE
θ value	0 (rank : 10)	NC score	0.977005 (rank : 16)
Query Neighborhood Hits	113	Target Neighborhood Hits	99	Shared Neighborhood Hits	89
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

MRP6_HUMAN
θ value	0 (rank : 11)	NC score	0.987378 (rank : 7)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	O95255, P78420, Q9UMZ7	Gene names	ABCC6, ARA, MRP6
Domain Architecture
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E).

MRP6_MOUSE
θ value	0 (rank : 12)	NC score	0.987460 (rank : 6)
Query Neighborhood Hits	113	Target Neighborhood Hits	105	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

MRP9_HUMAN
θ value	3.35459e-180 (rank : 13)	NC score	0.977907 (rank : 11)
Query Neighborhood Hits	113	Target Neighborhood Hits	114	Shared Neighborhood Hits	89
SwissProt Accessions	Q96J65, Q49AL2, Q8TAF0, Q8TEY2	Gene names	ABCC12, MRP9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MRP9_MOUSE
θ value	7.47326e-180 (rank : 14)	NC score	0.978439 (rank : 10)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	89
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

ABCCB_HUMAN
θ value	9.13544e-178 (rank : 15)	NC score	0.979763 (rank : 9)
Query Neighborhood Hits	113	Target Neighborhood Hits	118	Shared Neighborhood Hits	89
SwissProt Accessions	Q96J66, Q8TDJ0, Q96JA6, Q9BX80	Gene names	ABCC11, MRP8
Domain Architecture	No domain graphic available
Description	ATP-binding cassette transporter sub-family C member 11 (Multidrug resistance-associated protein 8).

ABCC8_HUMAN
θ value	2.58645e-156 (rank : 16)	NC score	0.976315 (rank : 17)
Query Neighborhood Hits	113	Target Neighborhood Hits	118	Shared Neighborhood Hits	89
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

MRP7_HUMAN
θ value	3.99958e-149 (rank : 17)	NC score	0.977196 (rank : 14)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q5T3U5, Q8NHX7, Q9H7N2, Q9NXY3, Q9UF48	Gene names	ABCC10, MRP7, SIMRP7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

MRP7_MOUSE
θ value	1.51984e-148 (rank : 18)	NC score	0.975582 (rank : 18)
Query Neighborhood Hits	113	Target Neighborhood Hits	99	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R4P9, Q3TCQ0, Q3V0D1, Q8R4S1	Gene names	Abcc10, Mrp7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

CFTR_HUMAN
θ value	1.20704e-137 (rank : 19)	NC score	0.944490 (rank : 19)
Query Neighborhood Hits	113	Target Neighborhood Hits	104	Shared Neighborhood Hits	90
SwissProt Accessions	P13569	Gene names	CFTR, ABCC7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

CFTR_MOUSE
θ value	3.34864e-71 (rank : 20)	NC score	0.940822 (rank : 20)
Query Neighborhood Hits	113	Target Neighborhood Hits	115	Shared Neighborhood Hits	89
SwissProt Accessions	P26361, Q63893, Q63894, Q9JKQ6	Gene names	Cftr, Abcc7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

ABCBB_HUMAN
θ value	2.1121e-49 (rank : 21)	NC score	0.827578 (rank : 33)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

ABCBB_MOUSE
θ value	2.67181e-44 (rank : 22)	NC score	0.821504 (rank : 34)
Query Neighborhood Hits	113	Target Neighborhood Hits	97	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

ABCBA_HUMAN
θ value	1.01529e-43 (rank : 23)	NC score	0.855305 (rank : 25)
Query Neighborhood Hits	113	Target Neighborhood Hits	102	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

ABCB9_MOUSE
θ value	3.05695e-40 (rank : 24)	NC score	0.840164 (rank : 28)
Query Neighborhood Hits	113	Target Neighborhood Hits	101	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JJ59, Q8CHA1, Q9D212, Q9JIN1	Gene names	Abcb9, Kiaa1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9).

ABCB9_HUMAN
θ value	1.16164e-39 (rank : 25)	NC score	0.839045 (rank : 29)
Query Neighborhood Hits	113	Target Neighborhood Hits	100	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NP78, Q96AB1, Q9P208	Gene names	ABCB9, KIAA1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9).

ABCBA_MOUSE
θ value	1.16164e-39 (rank : 26)	NC score	0.850984 (rank : 26)
Query Neighborhood Hits	113	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JI39, Q542P7, Q9D0C7	Gene names	Abcb10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein).

TAP2_MOUSE
θ value	6.37413e-38 (rank : 27)	NC score	0.860160 (rank : 22)
Query Neighborhood Hits	113	Target Neighborhood Hits	93	Shared Neighborhood Hits	87
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

MDR1_HUMAN
θ value	8.32485e-38 (rank : 28)	NC score	0.815805 (rank : 36)
Query Neighborhood Hits	113	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

TAP2_HUMAN
θ value	2.67802e-36 (rank : 29)	NC score	0.857933 (rank : 24)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

MDR1_MOUSE
θ value	1.01765e-35 (rank : 30)	NC score	0.819208 (rank : 35)
Query Neighborhood Hits	113	Target Neighborhood Hits	105	Shared Neighborhood Hits	91
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_MOUSE
θ value	1.73584e-35 (rank : 31)	NC score	0.810420 (rank : 37)
Query Neighborhood Hits	113	Target Neighborhood Hits	106	Shared Neighborhood Hits	91
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

MDR2_MOUSE
θ value	1.12514e-34 (rank : 32)	NC score	0.801309 (rank : 38)
Query Neighborhood Hits	113	Target Neighborhood Hits	108	Shared Neighborhood Hits	91
SwissProt Accessions	P21440, Q6LCL9	Gene names	Abcb4, Mdr2, Pgy-2, Pgy2
Domain Architecture
Description	Multidrug resistance protein 2 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 2).

ABCB5_HUMAN
θ value	7.29293e-34 (rank : 33)	NC score	0.831371 (rank : 32)
Query Neighborhood Hits	113	Target Neighborhood Hits	102	Shared Neighborhood Hits	91
SwissProt Accessions	Q2M3G0, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1	Gene names	ABCB5
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family B member 5 (P-glycoprotein ABCB5) (ABCB5 P-gp).

ABCB8_HUMAN
θ value	7.29293e-34 (rank : 34)	NC score	0.843365 (rank : 27)
Query Neighborhood Hits	113	Target Neighborhood Hits	91	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NUT2, O95787	Gene names	ABCB8, MABC1
Domain Architecture
Description	ATP-binding cassette sub-family B member 8, mitochondrial precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1).

MDR3_HUMAN
θ value	9.52487e-34 (rank : 35)	NC score	0.797830 (rank : 39)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	91
SwissProt Accessions	P21439, Q14813	Gene names	ABCB4, MDR3, PGY3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 3).

ABCB7_HUMAN
θ value	6.17384e-33 (rank : 36)	NC score	0.867028 (rank : 21)
Query Neighborhood Hits	113	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	O75027, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01	Gene names	ABCB7, ABC7
Domain Architecture
Description	ATP-binding cassette sub-family B member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein).

TAP1_HUMAN
θ value	1.0531e-32 (rank : 37)	NC score	0.832928 (rank : 31)
Query Neighborhood Hits	113	Target Neighborhood Hits	99	Shared Neighborhood Hits	89
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

TAP1_MOUSE
θ value	3.06405e-32 (rank : 38)	NC score	0.837653 (rank : 30)
Query Neighborhood Hits	113	Target Neighborhood Hits	95	Shared Neighborhood Hits	89
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

ABCB6_HUMAN
θ value	3.74554e-30 (rank : 39)	NC score	0.859267 (rank : 23)
Query Neighborhood Hits	113	Target Neighborhood Hits	105	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NP58, O75542	Gene names	ABCB6, MTABC3
Domain Architecture
Description	ATP-binding cassette sub-family B member 6, mitochondrial precursor (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (ABC transporter umat).

ABCCD_HUMAN
θ value	6.84181e-24 (rank : 40)	NC score	0.743602 (rank : 40)
Query Neighborhood Hits	113	Target Neighborhood Hits	24	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NSE7, Q8N6A4, Q8N6A5	Gene names	ABCC13, C21orf73, PRED6
Domain Architecture
Description	Putative ATP-binding cassette transporter C13.

ABCD3_MOUSE
θ value	1.86753e-13 (rank : 41)	NC score	0.577289 (rank : 45)
Query Neighborhood Hits	113	Target Neighborhood Hits	83	Shared Neighborhood Hits	77
SwissProt Accessions	P55096	Gene names	Abcd3, Pmp70, Pxmp1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70) (PMP68).

ABCD3_HUMAN
θ value	2.0648e-12 (rank : 42)	NC score	0.590019 (rank : 43)
Query Neighborhood Hits	113	Target Neighborhood Hits	85	Shared Neighborhood Hits	74
SwissProt Accessions	P28288, Q15271, Q9H529	Gene names	ABCD3, PMP70, PXMP1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70).

ABCG5_MOUSE
θ value	6.21693e-09 (rank : 43)	NC score	0.594037 (rank : 42)
Query Neighborhood Hits	113	Target Neighborhood Hits	95	Shared Neighborhood Hits	84
SwissProt Accessions	Q99PE8	Gene names	Abcg5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCA7_HUMAN
θ value	8.11959e-09 (rank : 44)	NC score	0.444003 (rank : 83)
Query Neighborhood Hits	113	Target Neighborhood Hits	144	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ABC8B_MOUSE
θ value	1.80886e-08 (rank : 45)	NC score	0.451078 (rank : 76)
Query Neighborhood Hits	113	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

ABCA1_MOUSE
θ value	1.80886e-08 (rank : 46)	NC score	0.458672 (rank : 70)
Query Neighborhood Hits	113	Target Neighborhood Hits	112	Shared Neighborhood Hits	87
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

ABCA4_HUMAN
θ value	1.80886e-08 (rank : 47)	NC score	0.463422 (rank : 68)
Query Neighborhood Hits	113	Target Neighborhood Hits	116	Shared Neighborhood Hits	89
SwissProt Accessions	P78363, O15112, O60438, O60915	Gene names	ABCA4, ABCR
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein).

ABCA4_MOUSE
θ value	1.80886e-08 (rank : 48)	NC score	0.465907 (rank : 66)
Query Neighborhood Hits	113	Target Neighborhood Hits	126	Shared Neighborhood Hits	88
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

ABCD1_HUMAN
θ value	1.80886e-08 (rank : 49)	NC score	0.527909 (rank : 49)
Query Neighborhood Hits	113	Target Neighborhood Hits	91	Shared Neighborhood Hits	78
SwissProt Accessions	P33897, Q6GTZ2	Gene names	ABCD1, ALD
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCD4_HUMAN
θ value	1.80886e-08 (rank : 50)	NC score	0.606591 (rank : 41)
Query Neighborhood Hits	113	Target Neighborhood Hits	95	Shared Neighborhood Hits	85
SwissProt Accessions	O14678	Gene names	ABCD4, PXMP1L
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCD2_MOUSE
θ value	2.36244e-08 (rank : 51)	NC score	0.526900 (rank : 51)
Query Neighborhood Hits	113	Target Neighborhood Hits	88	Shared Neighborhood Hits	76
SwissProt Accessions	Q61285, Q8BQ63, Q8C4B6	Gene names	Abcd2, Aldr
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein).

ABCA3_MOUSE
θ value	6.87365e-08 (rank : 52)	NC score	0.492547 (rank : 60)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R420	Gene names	Abca3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3.

ABCG5_HUMAN
θ value	8.97725e-08 (rank : 53)	NC score	0.559503 (rank : 46)
Query Neighborhood Hits	113	Target Neighborhood Hits	98	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H222	Gene names	ABCG5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABC8A_MOUSE
θ value	1.53129e-07 (rank : 54)	NC score	0.453346 (rank : 74)
Query Neighborhood Hits	113	Target Neighborhood Hits	115	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

ABCA9_MOUSE
θ value	1.99992e-07 (rank : 55)	NC score	0.448914 (rank : 78)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCAD_MOUSE
θ value	1.99992e-07 (rank : 56)	NC score	0.443106 (rank : 84)
Query Neighborhood Hits	113	Target Neighborhood Hits	150	Shared Neighborhood Hits	87
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCD4_MOUSE
θ value	1.99992e-07 (rank : 57)	NC score	0.582310 (rank : 44)
Query Neighborhood Hits	113	Target Neighborhood Hits	94	Shared Neighborhood Hits	83
SwissProt Accessions	O89016	Gene names	Abcd4, Pxmp1l
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCD2_HUMAN
θ value	2.61198e-07 (rank : 58)	NC score	0.511161 (rank : 54)
Query Neighborhood Hits	113	Target Neighborhood Hits	87	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UBJ2, Q13210	Gene names	ABCD2, ALD1, ALDL1, ALDR, ALDRP
Domain Architecture
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein) (hALDR) (Adrenoleukodystrophy-like 1).

ABCA3_HUMAN
θ value	3.41135e-07 (rank : 59)	NC score	0.501301 (rank : 57)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q99758, Q54A95, Q92473	Gene names	ABCA3, ABC3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter).

ABCA6_HUMAN
θ value	3.41135e-07 (rank : 60)	NC score	0.454838 (rank : 71)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N139, Q6NSH9, Q8N856, Q8WWZ6	Gene names	ABCA6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCD1_MOUSE
θ value	3.41135e-07 (rank : 61)	NC score	0.515686 (rank : 53)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	78
SwissProt Accessions	P48410, Q9QY41, Q9QZ32	Gene names	Abcd1, Ald, Aldgh
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCA5_MOUSE
θ value	4.45536e-07 (rank : 62)	NC score	0.473518 (rank : 62)
Query Neighborhood Hits	113	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA5_HUMAN
θ value	1.29631e-06 (rank : 63)	NC score	0.474983 (rank : 61)
Query Neighborhood Hits	113	Target Neighborhood Hits	146	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA6_MOUSE
θ value	1.29631e-06 (rank : 64)	NC score	0.446540 (rank : 81)
Query Neighborhood Hits	113	Target Neighborhood Hits	111	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCAA_HUMAN
θ value	1.29631e-06 (rank : 65)	NC score	0.451084 (rank : 75)
Query Neighborhood Hits	113	Target Neighborhood Hits	123	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

ABCA9_HUMAN
θ value	1.69304e-06 (rank : 66)	NC score	0.435290 (rank : 87)
Query Neighborhood Hits	113	Target Neighborhood Hits	111	Shared Neighborhood Hits	88
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCA1_HUMAN
θ value	2.88788e-06 (rank : 67)	NC score	0.454411 (rank : 72)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

ABCAC_HUMAN
θ value	2.88788e-06 (rank : 68)	NC score	0.453591 (rank : 73)
Query Neighborhood Hits	113	Target Neighborhood Hits	123	Shared Neighborhood Hits	88
SwissProt Accessions	Q86UK0, Q8IZW6, Q96JT3, Q9Y4M5	Gene names	ABCA12, ABC12
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12).

ABCG1_MOUSE
θ value	3.77169e-06 (rank : 69)	NC score	0.538581 (rank : 48)
Query Neighborhood Hits	113	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q64343	Gene names	Abcg1, Abc8, Wht1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCAD_HUMAN
θ value	4.92598e-06 (rank : 70)	NC score	0.438084 (rank : 85)
Query Neighborhood Hits	113	Target Neighborhood Hits	207	Shared Neighborhood Hits	84
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCG2_HUMAN
θ value	4.92598e-06 (rank : 71)	NC score	0.507671 (rank : 56)
Query Neighborhood Hits	113	Target Neighborhood Hits	84	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UNQ0, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64, Q8IX16, Q96LD6, Q96TA8, Q9BY73, Q9NUS0	Gene names	ABCG2, ABCP, BCRP, BCRP1, MXR
Domain Architecture
Description	ATP-binding cassette sub-family G member 2 (Placenta-specific ATP- binding cassette transporter) (Breast cancer resistance protein) (Mitoxantrone resistance-associated protein) (CDw338 antigen).

ABCG8_HUMAN
θ value	6.43352e-06 (rank : 72)	NC score	0.553821 (rank : 47)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H221	Gene names	ABCG8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCA2_HUMAN
θ value	8.40245e-06 (rank : 73)	NC score	0.448780 (rank : 80)
Query Neighborhood Hits	113	Target Neighborhood Hits	143	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA2_MOUSE
θ value	1.43324e-05 (rank : 74)	NC score	0.449471 (rank : 77)
Query Neighborhood Hits	113	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCF2_HUMAN
θ value	1.43324e-05 (rank : 75)	NC score	0.466217 (rank : 65)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UG63, O60864, Q96TE8	Gene names	ABCF2
Domain Architecture
Description	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2).

ABCF2_MOUSE
θ value	1.43324e-05 (rank : 76)	NC score	0.469781 (rank : 63)
Query Neighborhood Hits	113	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

ABCA8_HUMAN
θ value	2.44474e-05 (rank : 77)	NC score	0.418574 (rank : 88)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	90
SwissProt Accessions	O94911, Q86WW0	Gene names	ABCA8, KIAA0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8.

ABCA7_MOUSE
θ value	3.19293e-05 (rank : 78)	NC score	0.436543 (rank : 86)
Query Neighborhood Hits	113	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

ABCG1_HUMAN
θ value	3.19293e-05 (rank : 79)	NC score	0.527590 (rank : 50)
Query Neighborhood Hits	113	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P45844, Q86SU8, Q96L76, Q9BXK6, Q9BXK7, Q9BXK8, Q9BXK9, Q9BXL0, Q9BXL1, Q9BXL2, Q9BXL3, Q9BXL4	Gene names	ABCG1, ABC8, WHT1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCF3_HUMAN
θ value	5.44631e-05 (rank : 80)	NC score	0.460158 (rank : 69)
Query Neighborhood Hits	113	Target Neighborhood Hits	117	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NUQ8, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8	Gene names	ABCF3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCG2_MOUSE
θ value	5.44631e-05 (rank : 81)	NC score	0.510828 (rank : 55)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TMS5, Q9R004, Q9Z1T0	Gene names	Abcg2, Abcp, Bcrp1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein 1 homolog).

ABCF3_MOUSE
θ value	7.1131e-05 (rank : 82)	NC score	0.469137 (rank : 64)
Query Neighborhood Hits	113	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCG8_MOUSE
θ value	9.29e-05 (rank : 83)	NC score	0.526114 (rank : 52)
Query Neighborhood Hits	113	Target Neighborhood Hits	89	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBM0	Gene names	Abcg8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCF1_HUMAN
θ value	0.000786445 (rank : 84)	NC score	0.445490 (rank : 82)
Query Neighborhood Hits	113	Target Neighborhood Hits	343	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

ABCF1_MOUSE
θ value	0.000786445 (rank : 85)	NC score	0.448870 (rank : 79)
Query Neighborhood Hits	113	Target Neighborhood Hits	321	Shared Neighborhood Hits	89
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ABCE1_HUMAN
θ value	0.00298849 (rank : 86)	NC score	0.499910 (rank : 58)
Query Neighborhood Hits	113	Target Neighborhood Hits	114	Shared Neighborhood Hits	90
SwissProt Accessions	P61221, O88793, Q13181, Q13864, Q6NR76, Q96AL0, Q96B10, Q99K66	Gene names	ABCE1, RLI
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5' oligoadenylate-binding protein) (HuHP68).

ABCE1_MOUSE
θ value	0.00298849 (rank : 87)	NC score	0.499910 (rank : 59)
Query Neighborhood Hits	113	Target Neighborhood Hits	114	Shared Neighborhood Hits	90
SwissProt Accessions	P61222, O88793, Q13181, Q13864, Q96AL0, Q96B10, Q99K66	Gene names	Abce1, Rli
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I).

ABCG4_HUMAN
θ value	0.00390308 (rank : 88)	NC score	0.465598 (rank : 67)
Query Neighborhood Hits	113	Target Neighborhood Hits	90	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H172	Gene names	ABCG4, WHITE2
Domain Architecture
Description	ATP-binding cassette sub-family G member 4.

UTRO_HUMAN
θ value	0.0736092 (rank : 89)	NC score	0.003101 (rank : 109)
Query Neighborhood Hits	113	Target Neighborhood Hits	960	Shared Neighborhood Hits	7
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

NDST3_HUMAN
θ value	0.62314 (rank : 90)	NC score	0.015944 (rank : 94)
Query Neighborhood Hits	113	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST3_MOUSE
θ value	0.62314 (rank : 91)	NC score	0.015615 (rank : 95)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

VP13A_HUMAN
θ value	0.62314 (rank : 92)	NC score	0.017380 (rank : 92)
Query Neighborhood Hits	113	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

VPP4_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.009351 (rank : 101)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HBG4	Gene names	ATP6V0A4, ATP6N1B
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 (V- ATPase 116 kDa isoform a4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform).

ACSL4_HUMAN
θ value	2.36792 (rank : 94)	NC score	0.005073 (rank : 106)
Query Neighborhood Hits	113	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	O60488, O60848, O60849	Gene names	ACSL4, ACS4, FACL4, LACS4
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4).

GPR35_HUMAN
θ value	3.0926 (rank : 95)	NC score	-0.002869 (rank : 112)
Query Neighborhood Hits	113	Target Neighborhood Hits	630	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC97, O43495, Q86UH4	Gene names	GPR35
Domain Architecture
Description	Probable G-protein coupled receptor 35.

GPSN2_MOUSE
θ value	3.0926 (rank : 96)	NC score	0.009738 (rank : 100)
Query Neighborhood Hits	113	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CY27	Gene names	Gpsn2
Domain Architecture
Description	Synaptic glycoprotein SC2.

ASA3L_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.007151 (rank : 102)
Query Neighborhood Hits	113	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VD53, Q6PB92, Q8BUG3	Gene names	Asah3l, Acer2
Domain Architecture	No domain graphic available
Description	Alkaline ceramidase 2 (EC 3.5.1.23) (AlkCDase 2) (maCER2) (Acylsphingosine deacylase 3-like) (N-acylsphingosine amidohydrolase 3-like) (Cancer related gene-liver 1) (CRG-L1).

GGA2_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.006017 (rank : 103)
Query Neighborhood Hits	113	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

SMC2_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.016042 (rank : 93)
Query Neighborhood Hits	113	Target Neighborhood Hits	1405	Shared Neighborhood Hits	30
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC2_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.020790 (rank : 91)
Query Neighborhood Hits	113	Target Neighborhood Hits	1131	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

GGA2_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.005946 (rank : 104)
Query Neighborhood Hits	113	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

MMAA_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.013224 (rank : 96)
Query Neighborhood Hits	113	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C7H1, Q8R2N3, Q8VC22	Gene names	Mmaa
Domain Architecture
Description	Methylmalonic aciduria type A homolog, mitochondrial precursor.

NDST4_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.010168 (rank : 99)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST4_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.010198 (rank : 98)
Query Neighborhood Hits	113	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

ABCG3_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.246268 (rank : 89)
Query Neighborhood Hits	113	Target Neighborhood Hits	67	Shared Neighborhood Hits	58
SwissProt Accessions	Q99P81	Gene names	Abcg3
Domain Architecture
Description	ATP-binding cassette sub-family G member 3.

CHK1_HUMAN
θ value	6.88961 (rank : 106)	NC score	-0.007025 (rank : 113)
Query Neighborhood Hits	113	Target Neighborhood Hits	843	Shared Neighborhood Hits	2
SwissProt Accessions	O14757	Gene names	CHEK1, CHK1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).

DYH11_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.002677 (rank : 110)
Query Neighborhood Hits	113	Target Neighborhood Hits	234	Shared Neighborhood Hits	7
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

MTX2_MOUSE
θ value	6.88961 (rank : 108)	NC score	0.005919 (rank : 105)
Query Neighborhood Hits	113	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	O88441, Q3TFR2	Gene names	Mtx2
Domain Architecture	No domain graphic available
Description	Metaxin-2.

CK002_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.011932 (rank : 97)
Query Neighborhood Hits	113	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UID3, Q6PJV5, Q7L8A6, Q8WZ35, Q96DF4, Q96GR3	Gene names	C11orf2, ANG2
Domain Architecture	No domain graphic available
Description	Protein C11orf2 (Another new gene 2 protein).

CREB3_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.003526 (rank : 108)
Query Neighborhood Hits	113	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

FA57A_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.004303 (rank : 107)
Query Neighborhood Hits	113	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5ND56	Gene names	Fam57a
Domain Architecture	No domain graphic available
Description	Protein FAM57A.

MDN1_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.050355 (rank : 90)
Query Neighborhood Hits	113	Target Neighborhood Hits	662	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

NECD_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.000637 (rank : 111)
Query Neighborhood Hits	113	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

Hits sorted by NC score

MRP2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	113
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

MRP2_HUMAN
NC score	0.996578 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	113	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	Q92887, Q14022, Q92500, Q92798, Q99663, Q9UMS2	Gene names	ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein).

MRP1_HUMAN
NC score	0.993561 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	90
SwissProt Accessions	P33527, O14819, O43333, P78419, Q59GI9, Q9UQ97, Q9UQ99, Q9UQA0	Gene names	ABCC1, MRP, MRP1
Domain Architecture
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP1_MOUSE
NC score	0.993435 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	113	Target Neighborhood Hits	110	Shared Neighborhood Hits	90
SwissProt Accessions	O35379	Gene names	Abcc1, Abcc1a, Abcc1b, Mdrap, Mrp
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP3_HUMAN
NC score	0.993174 (rank : 5)	θ value	0 (rank : 7)
Query Neighborhood Hits	113	Target Neighborhood Hits	125	Shared Neighborhood Hits	92
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

MRP6_MOUSE
NC score	0.987460 (rank : 6)	θ value	0 (rank : 12)
Query Neighborhood Hits	113	Target Neighborhood Hits	105	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

MRP6_HUMAN
NC score	0.987378 (rank : 7)	θ value	0 (rank : 11)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	O95255, P78420, Q9UMZ7	Gene names	ABCC6, ARA, MRP6
Domain Architecture
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E).

MRP4_HUMAN
NC score	0.987263 (rank : 8)	θ value	0 (rank : 8)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	90
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

ABCCB_HUMAN
NC score	0.979763 (rank : 9)	θ value	9.13544e-178 (rank : 15)
Query Neighborhood Hits	113	Target Neighborhood Hits	118	Shared Neighborhood Hits	89
SwissProt Accessions	Q96J66, Q8TDJ0, Q96JA6, Q9BX80	Gene names	ABCC11, MRP8
Domain Architecture	No domain graphic available
Description	ATP-binding cassette transporter sub-family C member 11 (Multidrug resistance-associated protein 8).

MRP9_MOUSE
NC score	0.978439 (rank : 10)	θ value	7.47326e-180 (rank : 14)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	89
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MRP9_HUMAN
NC score	0.977907 (rank : 11)	θ value	3.35459e-180 (rank : 13)
Query Neighborhood Hits	113	Target Neighborhood Hits	114	Shared Neighborhood Hits	89
SwissProt Accessions	Q96J65, Q49AL2, Q8TAF0, Q8TEY2	Gene names	ABCC12, MRP9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MRP5_HUMAN
NC score	0.977699 (rank : 12)	θ value	0 (rank : 9)
Query Neighborhood Hits	113	Target Neighborhood Hits	110	Shared Neighborhood Hits	89
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

ABCC9_MOUSE
NC score	0.977241 (rank : 13)	θ value	0 (rank : 2)
Query Neighborhood Hits	113	Target Neighborhood Hits	110	Shared Neighborhood Hits	89
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

MRP7_HUMAN
NC score	0.977196 (rank : 14)	θ value	3.99958e-149 (rank : 17)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q5T3U5, Q8NHX7, Q9H7N2, Q9NXY3, Q9UF48	Gene names	ABCC10, MRP7, SIMRP7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

ABCC9_HUMAN
NC score	0.977100 (rank : 15)	θ value	0 (rank : 1)
Query Neighborhood Hits	113	Target Neighborhood Hits	108	Shared Neighborhood Hits	90
SwissProt Accessions	O60706, O60707	Gene names	ABCC9, SUR2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

MRP5_MOUSE
NC score	0.977005 (rank : 16)	θ value	0 (rank : 10)
Query Neighborhood Hits	113	Target Neighborhood Hits	99	Shared Neighborhood Hits	89
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

ABCC8_HUMAN
NC score	0.976315 (rank : 17)	θ value	2.58645e-156 (rank : 16)
Query Neighborhood Hits	113	Target Neighborhood Hits	118	Shared Neighborhood Hits	89
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

MRP7_MOUSE
NC score	0.975582 (rank : 18)	θ value	1.51984e-148 (rank : 18)
Query Neighborhood Hits	113	Target Neighborhood Hits	99	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R4P9, Q3TCQ0, Q3V0D1, Q8R4S1	Gene names	Abcc10, Mrp7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

CFTR_HUMAN
NC score	0.944490 (rank : 19)	θ value	1.20704e-137 (rank : 19)
Query Neighborhood Hits	113	Target Neighborhood Hits	104	Shared Neighborhood Hits	90
SwissProt Accessions	P13569	Gene names	CFTR, ABCC7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

CFTR_MOUSE
NC score	0.940822 (rank : 20)	θ value	3.34864e-71 (rank : 20)
Query Neighborhood Hits	113	Target Neighborhood Hits	115	Shared Neighborhood Hits	89
SwissProt Accessions	P26361, Q63893, Q63894, Q9JKQ6	Gene names	Cftr, Abcc7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

ABCB7_HUMAN
NC score	0.867028 (rank : 21)	θ value	6.17384e-33 (rank : 36)
Query Neighborhood Hits	113	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	O75027, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01	Gene names	ABCB7, ABC7
Domain Architecture
Description	ATP-binding cassette sub-family B member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein).

TAP2_MOUSE
NC score	0.860160 (rank : 22)	θ value	6.37413e-38 (rank : 27)
Query Neighborhood Hits	113	Target Neighborhood Hits	93	Shared Neighborhood Hits	87
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

ABCB6_HUMAN
NC score	0.859267 (rank : 23)	θ value	3.74554e-30 (rank : 39)
Query Neighborhood Hits	113	Target Neighborhood Hits	105	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NP58, O75542	Gene names	ABCB6, MTABC3
Domain Architecture
Description	ATP-binding cassette sub-family B member 6, mitochondrial precursor (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (ABC transporter umat).

TAP2_HUMAN
NC score	0.857933 (rank : 24)	θ value	2.67802e-36 (rank : 29)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

ABCBA_HUMAN
NC score	0.855305 (rank : 25)	θ value	1.01529e-43 (rank : 23)
Query Neighborhood Hits	113	Target Neighborhood Hits	102	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

ABCBA_MOUSE
NC score	0.850984 (rank : 26)	θ value	1.16164e-39 (rank : 26)
Query Neighborhood Hits	113	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JI39, Q542P7, Q9D0C7	Gene names	Abcb10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein).

ABCB8_HUMAN
NC score	0.843365 (rank : 27)	θ value	7.29293e-34 (rank : 34)
Query Neighborhood Hits	113	Target Neighborhood Hits	91	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NUT2, O95787	Gene names	ABCB8, MABC1
Domain Architecture
Description	ATP-binding cassette sub-family B member 8, mitochondrial precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1).

ABCB9_MOUSE
NC score	0.840164 (rank : 28)	θ value	3.05695e-40 (rank : 24)
Query Neighborhood Hits	113	Target Neighborhood Hits	101	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JJ59, Q8CHA1, Q9D212, Q9JIN1	Gene names	Abcb9, Kiaa1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9).

ABCB9_HUMAN
NC score	0.839045 (rank : 29)	θ value	1.16164e-39 (rank : 25)
Query Neighborhood Hits	113	Target Neighborhood Hits	100	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NP78, Q96AB1, Q9P208	Gene names	ABCB9, KIAA1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9).

TAP1_MOUSE
NC score	0.837653 (rank : 30)	θ value	3.06405e-32 (rank : 38)
Query Neighborhood Hits	113	Target Neighborhood Hits	95	Shared Neighborhood Hits	89
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

TAP1_HUMAN
NC score	0.832928 (rank : 31)	θ value	1.0531e-32 (rank : 37)
Query Neighborhood Hits	113	Target Neighborhood Hits	99	Shared Neighborhood Hits	89
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

ABCB5_HUMAN
NC score	0.831371 (rank : 32)	θ value	7.29293e-34 (rank : 33)
Query Neighborhood Hits	113	Target Neighborhood Hits	102	Shared Neighborhood Hits	91
SwissProt Accessions	Q2M3G0, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1	Gene names	ABCB5
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family B member 5 (P-glycoprotein ABCB5) (ABCB5 P-gp).

ABCBB_HUMAN
NC score	0.827578 (rank : 33)	θ value	2.1121e-49 (rank : 21)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

ABCBB_MOUSE
NC score	0.821504 (rank : 34)	θ value	2.67181e-44 (rank : 22)
Query Neighborhood Hits	113	Target Neighborhood Hits	97	Shared Neighborhood Hits	88
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

MDR1_MOUSE
NC score	0.819208 (rank : 35)	θ value	1.01765e-35 (rank : 30)
Query Neighborhood Hits	113	Target Neighborhood Hits	105	Shared Neighborhood Hits	91
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR1_HUMAN
NC score	0.815805 (rank : 36)	θ value	8.32485e-38 (rank : 28)
Query Neighborhood Hits	113	Target Neighborhood Hits	112	Shared Neighborhood Hits	91
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_MOUSE
NC score	0.810420 (rank : 37)	θ value	1.73584e-35 (rank : 31)
Query Neighborhood Hits	113	Target Neighborhood Hits	106	Shared Neighborhood Hits	91
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

MDR2_MOUSE
NC score	0.801309 (rank : 38)	θ value	1.12514e-34 (rank : 32)
Query Neighborhood Hits	113	Target Neighborhood Hits	108	Shared Neighborhood Hits	91
SwissProt Accessions	P21440, Q6LCL9	Gene names	Abcb4, Mdr2, Pgy-2, Pgy2
Domain Architecture
Description	Multidrug resistance protein 2 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 2).

MDR3_HUMAN
NC score	0.797830 (rank : 39)	θ value	9.52487e-34 (rank : 35)
Query Neighborhood Hits	113	Target Neighborhood Hits	103	Shared Neighborhood Hits	91
SwissProt Accessions	P21439, Q14813	Gene names	ABCB4, MDR3, PGY3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 3).

ABCCD_HUMAN
NC score	0.743602 (rank : 40)	θ value	6.84181e-24 (rank : 40)
Query Neighborhood Hits	113	Target Neighborhood Hits	24	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NSE7, Q8N6A4, Q8N6A5	Gene names	ABCC13, C21orf73, PRED6
Domain Architecture
Description	Putative ATP-binding cassette transporter C13.

ABCD4_HUMAN
NC score	0.606591 (rank : 41)	θ value	1.80886e-08 (rank : 50)
Query Neighborhood Hits	113	Target Neighborhood Hits	95	Shared Neighborhood Hits	85
SwissProt Accessions	O14678	Gene names	ABCD4, PXMP1L
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCG5_MOUSE
NC score	0.594037 (rank : 42)	θ value	6.21693e-09 (rank : 43)
Query Neighborhood Hits	113	Target Neighborhood Hits	95	Shared Neighborhood Hits	84
SwissProt Accessions	Q99PE8	Gene names	Abcg5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCD3_HUMAN
NC score	0.590019 (rank : 43)	θ value	2.0648e-12 (rank : 42)
Query Neighborhood Hits	113	Target Neighborhood Hits	85	Shared Neighborhood Hits	74
SwissProt Accessions	P28288, Q15271, Q9H529	Gene names	ABCD3, PMP70, PXMP1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70).

ABCD4_MOUSE
NC score	0.582310 (rank : 44)	θ value	1.99992e-07 (rank : 57)
Query Neighborhood Hits	113	Target Neighborhood Hits	94	Shared Neighborhood Hits	83
SwissProt Accessions	O89016	Gene names	Abcd4, Pxmp1l
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCD3_MOUSE
NC score	0.577289 (rank : 45)	θ value	1.86753e-13 (rank : 41)
Query Neighborhood Hits	113	Target Neighborhood Hits	83	Shared Neighborhood Hits	77
SwissProt Accessions	P55096	Gene names	Abcd3, Pmp70, Pxmp1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70) (PMP68).

ABCG5_HUMAN
NC score	0.559503 (rank : 46)	θ value	8.97725e-08 (rank : 53)
Query Neighborhood Hits	113	Target Neighborhood Hits	98	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H222	Gene names	ABCG5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCG8_HUMAN
NC score	0.553821 (rank : 47)	θ value	6.43352e-06 (rank : 72)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H221	Gene names	ABCG8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCG1_MOUSE
NC score	0.538581 (rank : 48)	θ value	3.77169e-06 (rank : 69)
Query Neighborhood Hits	113	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q64343	Gene names	Abcg1, Abc8, Wht1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCD1_HUMAN
NC score	0.527909 (rank : 49)	θ value	1.80886e-08 (rank : 49)
Query Neighborhood Hits	113	Target Neighborhood Hits	91	Shared Neighborhood Hits	78
SwissProt Accessions	P33897, Q6GTZ2	Gene names	ABCD1, ALD
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCG1_HUMAN
NC score	0.527590 (rank : 50)	θ value	3.19293e-05 (rank : 79)
Query Neighborhood Hits	113	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P45844, Q86SU8, Q96L76, Q9BXK6, Q9BXK7, Q9BXK8, Q9BXK9, Q9BXL0, Q9BXL1, Q9BXL2, Q9BXL3, Q9BXL4	Gene names	ABCG1, ABC8, WHT1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCD2_MOUSE
NC score	0.526900 (rank : 51)	θ value	2.36244e-08 (rank : 51)
Query Neighborhood Hits	113	Target Neighborhood Hits	88	Shared Neighborhood Hits	76
SwissProt Accessions	Q61285, Q8BQ63, Q8C4B6	Gene names	Abcd2, Aldr
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein).

ABCG8_MOUSE
NC score	0.526114 (rank : 52)	θ value	9.29e-05 (rank : 83)
Query Neighborhood Hits	113	Target Neighborhood Hits	89	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBM0	Gene names	Abcg8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCD1_MOUSE
NC score	0.515686 (rank : 53)	θ value	3.41135e-07 (rank : 61)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	78
SwissProt Accessions	P48410, Q9QY41, Q9QZ32	Gene names	Abcd1, Ald, Aldgh
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCD2_HUMAN
NC score	0.511161 (rank : 54)	θ value	2.61198e-07 (rank : 58)
Query Neighborhood Hits	113	Target Neighborhood Hits	87	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UBJ2, Q13210	Gene names	ABCD2, ALD1, ALDL1, ALDR, ALDRP
Domain Architecture
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein) (hALDR) (Adrenoleukodystrophy-like 1).

ABCG2_MOUSE
NC score	0.510828 (rank : 55)	θ value	5.44631e-05 (rank : 81)
Query Neighborhood Hits	113	Target Neighborhood Hits	92	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TMS5, Q9R004, Q9Z1T0	Gene names	Abcg2, Abcp, Bcrp1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein 1 homolog).

ABCG2_HUMAN
NC score	0.507671 (rank : 56)	θ value	4.92598e-06 (rank : 71)
Query Neighborhood Hits	113	Target Neighborhood Hits	84	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UNQ0, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64, Q8IX16, Q96LD6, Q96TA8, Q9BY73, Q9NUS0	Gene names	ABCG2, ABCP, BCRP, BCRP1, MXR
Domain Architecture
Description	ATP-binding cassette sub-family G member 2 (Placenta-specific ATP- binding cassette transporter) (Breast cancer resistance protein) (Mitoxantrone resistance-associated protein) (CDw338 antigen).

ABCA3_HUMAN
NC score	0.501301 (rank : 57)	θ value	3.41135e-07 (rank : 59)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q99758, Q54A95, Q92473	Gene names	ABCA3, ABC3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter).

ABCE1_HUMAN
NC score	0.499910 (rank : 58)	θ value	0.00298849 (rank : 86)
Query Neighborhood Hits	113	Target Neighborhood Hits	114	Shared Neighborhood Hits	90
SwissProt Accessions	P61221, O88793, Q13181, Q13864, Q6NR76, Q96AL0, Q96B10, Q99K66	Gene names	ABCE1, RLI
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5' oligoadenylate-binding protein) (HuHP68).

ABCE1_MOUSE
NC score	0.499910 (rank : 59)	θ value	0.00298849 (rank : 87)
Query Neighborhood Hits	113	Target Neighborhood Hits	114	Shared Neighborhood Hits	90
SwissProt Accessions	P61222, O88793, Q13181, Q13864, Q96AL0, Q96B10, Q99K66	Gene names	Abce1, Rli
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I).

ABCA3_MOUSE
NC score	0.492547 (rank : 60)	θ value	6.87365e-08 (rank : 52)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R420	Gene names	Abca3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3.

ABCA5_HUMAN
NC score	0.474983 (rank : 61)	θ value	1.29631e-06 (rank : 63)
Query Neighborhood Hits	113	Target Neighborhood Hits	146	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA5_MOUSE
NC score	0.473518 (rank : 62)	θ value	4.45536e-07 (rank : 62)
Query Neighborhood Hits	113	Target Neighborhood Hits	137	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCF2_MOUSE
NC score	0.469781 (rank : 63)	θ value	1.43324e-05 (rank : 76)
Query Neighborhood Hits	113	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

ABCF3_MOUSE
NC score	0.469137 (rank : 64)	θ value	7.1131e-05 (rank : 82)
Query Neighborhood Hits	113	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCF2_HUMAN
NC score	0.466217 (rank : 65)	θ value	1.43324e-05 (rank : 75)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UG63, O60864, Q96TE8	Gene names	ABCF2
Domain Architecture
Description	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2).

ABCA4_MOUSE
NC score	0.465907 (rank : 66)	θ value	1.80886e-08 (rank : 48)
Query Neighborhood Hits	113	Target Neighborhood Hits	126	Shared Neighborhood Hits	88
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

ABCG4_HUMAN
NC score	0.465598 (rank : 67)	θ value	0.00390308 (rank : 88)
Query Neighborhood Hits	113	Target Neighborhood Hits	90	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H172	Gene names	ABCG4, WHITE2
Domain Architecture
Description	ATP-binding cassette sub-family G member 4.

ABCA4_HUMAN
NC score	0.463422 (rank : 68)	θ value	1.80886e-08 (rank : 47)
Query Neighborhood Hits	113	Target Neighborhood Hits	116	Shared Neighborhood Hits	89
SwissProt Accessions	P78363, O15112, O60438, O60915	Gene names	ABCA4, ABCR
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein).

ABCF3_HUMAN
NC score	0.460158 (rank : 69)	θ value	5.44631e-05 (rank : 80)
Query Neighborhood Hits	113	Target Neighborhood Hits	117	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NUQ8, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8	Gene names	ABCF3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCA1_MOUSE
NC score	0.458672 (rank : 70)	θ value	1.80886e-08 (rank : 46)
Query Neighborhood Hits	113	Target Neighborhood Hits	112	Shared Neighborhood Hits	87
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

ABCA6_HUMAN
NC score	0.454838 (rank : 71)	θ value	3.41135e-07 (rank : 60)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N139, Q6NSH9, Q8N856, Q8WWZ6	Gene names	ABCA6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA1_HUMAN
NC score	0.454411 (rank : 72)	θ value	2.88788e-06 (rank : 67)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

ABCAC_HUMAN
NC score	0.453591 (rank : 73)	θ value	2.88788e-06 (rank : 68)
Query Neighborhood Hits	113	Target Neighborhood Hits	123	Shared Neighborhood Hits	88
SwissProt Accessions	Q86UK0, Q8IZW6, Q96JT3, Q9Y4M5	Gene names	ABCA12, ABC12
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12).

ABC8A_MOUSE
NC score	0.453346 (rank : 74)	θ value	1.53129e-07 (rank : 54)
Query Neighborhood Hits	113	Target Neighborhood Hits	115	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

ABCAA_HUMAN
NC score	0.451084 (rank : 75)	θ value	1.29631e-06 (rank : 65)
Query Neighborhood Hits	113	Target Neighborhood Hits	123	Shared Neighborhood Hits	88
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

ABC8B_MOUSE
NC score	0.451078 (rank : 76)	θ value	1.80886e-08 (rank : 45)
Query Neighborhood Hits	113	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

ABCA2_MOUSE
NC score	0.449471 (rank : 77)	θ value	1.43324e-05 (rank : 74)
Query Neighborhood Hits	113	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA9_MOUSE
NC score	0.448914 (rank : 78)	θ value	1.99992e-07 (rank : 55)
Query Neighborhood Hits	113	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCF1_MOUSE
NC score	0.448870 (rank : 79)	θ value	0.000786445 (rank : 85)
Query Neighborhood Hits	113	Target Neighborhood Hits	321	Shared Neighborhood Hits	89
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ABCA2_HUMAN
NC score	0.448780 (rank : 80)	θ value	8.40245e-06 (rank : 73)
Query Neighborhood Hits	113	Target Neighborhood Hits	143	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA6_MOUSE
NC score	0.446540 (rank : 81)	θ value	1.29631e-06 (rank : 64)
Query Neighborhood Hits	113	Target Neighborhood Hits	111	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCF1_HUMAN
NC score	0.445490 (rank : 82)	θ value	0.000786445 (rank : 84)
Query Neighborhood Hits	113	Target Neighborhood Hits	343	Shared Neighborhood Hits	89
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

ABCA7_HUMAN
NC score	0.444003 (rank : 83)	θ value	8.11959e-09 (rank : 44)
Query Neighborhood Hits	113	Target Neighborhood Hits	144	Shared Neighborhood Hits	83
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ABCAD_MOUSE
NC score	0.443106 (rank : 84)	θ value	1.99992e-07 (rank : 56)
Query Neighborhood Hits	113	Target Neighborhood Hits	150	Shared Neighborhood Hits	87
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCAD_HUMAN
NC score	0.438084 (rank : 85)	θ value	4.92598e-06 (rank : 70)
Query Neighborhood Hits	113	Target Neighborhood Hits	207	Shared Neighborhood Hits	84
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCA7_MOUSE
NC score	0.436543 (rank : 86)	θ value	3.19293e-05 (rank : 78)
Query Neighborhood Hits	113	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

ABCA9_HUMAN
NC score	0.435290 (rank : 87)	θ value	1.69304e-06 (rank : 66)
Query Neighborhood Hits	113	Target Neighborhood Hits	111	Shared Neighborhood Hits	88
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCA8_HUMAN
NC score	0.418574 (rank : 88)	θ value	2.44474e-05 (rank : 77)
Query Neighborhood Hits	113	Target Neighborhood Hits	113	Shared Neighborhood Hits	90
SwissProt Accessions	O94911, Q86WW0	Gene names	ABCA8, KIAA0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8.

ABCG3_MOUSE
NC score	0.246268 (rank : 89)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	113	Target Neighborhood Hits	67	Shared Neighborhood Hits	58
SwissProt Accessions	Q99P81	Gene names	Abcg3
Domain Architecture
Description	ATP-binding cassette sub-family G member 3.

MDN1_HUMAN
NC score	0.050355 (rank : 90)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	113	Target Neighborhood Hits	662	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

SMC2_MOUSE
NC score	0.020790 (rank : 91)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	113	Target Neighborhood Hits	1131	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

VP13A_HUMAN
NC score	0.017380 (rank : 92)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	113	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RL7, Q5JSX9, Q5JSY0, Q5VYR5, Q702P4, Q709D0, Q86YF8, Q96S61, Q9H995, Q9Y2J1	Gene names	VPS13A, CHAC, KIAA0986
Domain Architecture
Description	Vacuolar protein sorting-associated protein 13A (Chorein) (Chorea- acanthocytosis protein).

SMC2_HUMAN
NC score	0.016042 (rank : 93)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	113	Target Neighborhood Hits	1405	Shared Neighborhood Hits	30
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

NDST3_HUMAN
NC score	0.015944 (rank : 94)	θ value	0.62314 (rank : 90)
Query Neighborhood Hits	113	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	O95803, Q4W5C1, Q4W5D0, Q6UWC5, Q9UP21	Gene names	NDST3, HSST3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (hNDST-3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 3 (EC 2.8.2.-)].

NDST3_MOUSE
NC score	0.015615 (rank : 95)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQH7, Q6AXE0, Q9D557	Gene names	Ndst3, Hsst3
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 3) (NDST- 3) (N-heparan sulfate sulfotransferase 3) (N-HSST 3) [Includes: Heparan sulfate N-deacetylase 3 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 3 (EC 2.8.2.-)].

MMAA_MOUSE
NC score	0.013224 (rank : 96)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	113	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C7H1, Q8R2N3, Q8VC22	Gene names	Mmaa
Domain Architecture
Description	Methylmalonic aciduria type A homolog, mitochondrial precursor.

CK002_HUMAN
NC score	0.011932 (rank : 97)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	113	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UID3, Q6PJV5, Q7L8A6, Q8WZ35, Q96DF4, Q96GR3	Gene names	C11orf2, ANG2
Domain Architecture	No domain graphic available
Description	Protein C11orf2 (Another new gene 2 protein).

NDST4_MOUSE
NC score	0.010198 (rank : 98)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	113	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EQW8	Gene names	Ndst4, Hsst4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

NDST4_HUMAN
NC score	0.010168 (rank : 99)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	113	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H3R1	Gene names	NDST4, HSST4
Domain Architecture	No domain graphic available
Description	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 4) (NDST- 4) (N-heparan sulfate sulfotransferase 4) (N-HSST 4) [Includes: Heparan sulfate N-deacetylase 4 (EC 3.-.-.-); Heparan sulfate N- sulfotransferase 4 (EC 2.8.2.-)].

GPSN2_MOUSE
NC score	0.009738 (rank : 100)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	113	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CY27	Gene names	Gpsn2
Domain Architecture
Description	Synaptic glycoprotein SC2.

VPP4_HUMAN
NC score	0.009351 (rank : 101)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	113	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HBG4	Gene names	ATP6V0A4, ATP6N1B
Domain Architecture
Description	Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4 (V- ATPase 116 kDa isoform a4) (Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform).

ASA3L_MOUSE
NC score	0.007151 (rank : 102)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	113	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VD53, Q6PB92, Q8BUG3	Gene names	Asah3l, Acer2
Domain Architecture	No domain graphic available
Description	Alkaline ceramidase 2 (EC 3.5.1.23) (AlkCDase 2) (maCER2) (Acylsphingosine deacylase 3-like) (N-acylsphingosine amidohydrolase 3-like) (Cancer related gene-liver 1) (CRG-L1).

GGA2_HUMAN
NC score	0.006017 (rank : 103)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	113	Target Neighborhood Hits	114	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJY4, O14564, Q9NYN2, Q9UPS2	Gene names	GGA2, KIAA1080
Domain Architecture
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear).

GGA2_MOUSE
NC score	0.005946 (rank : 104)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	113	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P5E6, Q3U374, Q6PFX3, Q6ZPY8, Q8BM76, Q9DC15	Gene names	Gga2, Kiaa1080
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA2 (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (Gamma-adaptin-related protein 2).

MTX2_MOUSE
NC score	0.005919 (rank : 105)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	113	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	O88441, Q3TFR2	Gene names	Mtx2
Domain Architecture	No domain graphic available
Description	Metaxin-2.

ACSL4_HUMAN
NC score	0.005073 (rank : 106)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	113	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	O60488, O60848, O60849	Gene names	ACSL4, ACS4, FACL4, LACS4
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4).

FA57A_MOUSE
NC score	0.004303 (rank : 107)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	113	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q5ND56	Gene names	Fam57a
Domain Architecture	No domain graphic available
Description	Protein FAM57A.

CREB3_MOUSE
NC score	0.003526 (rank : 108)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	113	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q61817, Q99M21, Q9CVK9	Gene names	Creb3, Lzip
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Transcription factor LZIP).

UTRO_HUMAN
NC score	0.003101 (rank : 109)	θ value	0.0736092 (rank : 89)
Query Neighborhood Hits	113	Target Neighborhood Hits	960	Shared Neighborhood Hits	7
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

DYH11_HUMAN
NC score	0.002677 (rank : 110)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	113	Target Neighborhood Hits	234	Shared Neighborhood Hits	7
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

NECD_HUMAN
NC score	0.000637 (rank : 111)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	113	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q99608	Gene names	NDN
Domain Architecture
Description	Necdin.

GPR35_HUMAN
NC score	-0.002869 (rank : 112)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	113	Target Neighborhood Hits	630	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HC97, O43495, Q86UH4	Gene names	GPR35
Domain Architecture
Description	Probable G-protein coupled receptor 35.

CHK1_HUMAN
NC score	-0.007025 (rank : 113)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	113	Target Neighborhood Hits	843	Shared Neighborhood Hits	2
SwissProt Accessions	O14757	Gene names	CHEK1, CHK1
Domain Architecture
Description	Serine/threonine-protein kinase Chk1 (EC 2.7.11.1).