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Network neighborhood for query Sequence : MDR1_HUMAN

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MDR1_HUMAN
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ABCB5_HUMAN
θ value	0 (rank : 1)	NC score	0.993697 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	96
SwissProt Accessions	Q2M3G0, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1	Gene names	ABCB5
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family B member 5 (P-glycoprotein ABCB5) (ABCB5 P-gp).

ABCBB_HUMAN
θ value	0 (rank : 2)	NC score	0.993593 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	89
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

ABCBB_MOUSE
θ value	0 (rank : 3)	NC score	0.993155 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

MDR1_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR1_MOUSE
θ value	0 (rank : 5)	NC score	0.997469 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR2_MOUSE
θ value	0 (rank : 6)	NC score	0.997826 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	108	Shared Neighborhood Hits	100
SwissProt Accessions	P21440, Q6LCL9	Gene names	Abcb4, Mdr2, Pgy-2, Pgy2
Domain Architecture
Description	Multidrug resistance protein 2 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 2).

MDR3_HUMAN
θ value	0 (rank : 7)	NC score	0.997627 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	P21439, Q14813	Gene names	ABCB4, MDR3, PGY3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 3).

MDR3_MOUSE
θ value	0 (rank : 8)	NC score	0.998332 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

ABCBA_HUMAN
θ value	3.9282e-96 (rank : 9)	NC score	0.961039 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

ABCBA_MOUSE
θ value	5.1304e-96 (rank : 10)	NC score	0.960874 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	97	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JI39, Q542P7, Q9D0C7	Gene names	Abcb10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein).

ABCB9_MOUSE
θ value	3.33315e-87 (rank : 11)	NC score	0.947334 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JJ59, Q8CHA1, Q9D212, Q9JIN1	Gene names	Abcb9, Kiaa1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9).

ABCB9_HUMAN
θ value	1.65422e-86 (rank : 12)	NC score	0.947399 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NP78, Q96AB1, Q9P208	Gene names	ABCB9, KIAA1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9).

ABCB8_HUMAN
θ value	3.11973e-85 (rank : 13)	NC score	0.962057 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NUT2, O95787	Gene names	ABCB8, MABC1
Domain Architecture
Description	ATP-binding cassette sub-family B member 8, mitochondrial precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1).

TAP1_MOUSE
θ value	1.66191e-70 (rank : 14)	NC score	0.943098 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	89
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

TAP2_MOUSE
θ value	2.3998e-69 (rank : 15)	NC score	0.942985 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	93	Shared Neighborhood Hits	87
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

TAP1_HUMAN
θ value	1.71981e-67 (rank : 16)	NC score	0.942700 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	91
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

TAP2_HUMAN
θ value	1.04338e-64 (rank : 17)	NC score	0.940738 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

ABCB6_HUMAN
θ value	2.56992e-63 (rank : 18)	NC score	0.947489 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NP58, O75542	Gene names	ABCB6, MTABC3
Domain Architecture
Description	ATP-binding cassette sub-family B member 6, mitochondrial precursor (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (ABC transporter umat).

MRP5_HUMAN
θ value	5.7252e-63 (rank : 19)	NC score	0.847851 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

MRP2_HUMAN
θ value	8.26713e-62 (rank : 20)	NC score	0.841323 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q92887, Q14022, Q92500, Q92798, Q99663, Q9UMS2	Gene names	ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein).

MRP1_MOUSE
θ value	3.14151e-61 (rank : 21)	NC score	0.817033 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	90
SwissProt Accessions	O35379	Gene names	Abcc1, Abcc1a, Abcc1b, Mdrap, Mrp
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP5_MOUSE
θ value	2.03627e-60 (rank : 22)	NC score	0.846463 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

MRP3_HUMAN
θ value	2.84797e-54 (rank : 23)	NC score	0.821763 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	125	Shared Neighborhood Hits	93
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

ABCB7_HUMAN
θ value	1.41344e-53 (rank : 24)	NC score	0.941532 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	92
SwissProt Accessions	O75027, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01	Gene names	ABCB7, ABC7
Domain Architecture
Description	ATP-binding cassette sub-family B member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein).

ABCC8_HUMAN
θ value	1.32293e-51 (rank : 25)	NC score	0.813382 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	118	Shared Neighborhood Hits	88
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

MRP6_HUMAN
θ value	4.70527e-49 (rank : 26)	NC score	0.827483 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	90
SwissProt Accessions	O95255, P78420, Q9UMZ7	Gene names	ABCC6, ARA, MRP6
Domain Architecture
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E).

MRP6_MOUSE
θ value	1.51363e-47 (rank : 27)	NC score	0.820909 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

MRP2_MOUSE
θ value	8.32485e-38 (rank : 28)	NC score	0.815805 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

MRP1_HUMAN
θ value	1.08726e-37 (rank : 29)	NC score	0.813477 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	90
SwissProt Accessions	P33527, O14819, O43333, P78419, Q59GI9, Q9UQ97, Q9UQ99, Q9UQA0	Gene names	ABCC1, MRP, MRP1
Domain Architecture
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP9_MOUSE
θ value	9.20422e-37 (rank : 30)	NC score	0.831445 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MRP9_HUMAN
θ value	1.20211e-36 (rank : 31)	NC score	0.818358 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	114	Shared Neighborhood Hits	88
SwissProt Accessions	Q96J65, Q49AL2, Q8TAF0, Q8TEY2	Gene names	ABCC12, MRP9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MRP7_HUMAN
θ value	1.46948e-34 (rank : 32)	NC score	0.832494 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q5T3U5, Q8NHX7, Q9H7N2, Q9NXY3, Q9UF48	Gene names	ABCC10, MRP7, SIMRP7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

ABCCB_HUMAN
θ value	3.27365e-34 (rank : 33)	NC score	0.823061 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	118	Shared Neighborhood Hits	89
SwissProt Accessions	Q96J66, Q8TDJ0, Q96JA6, Q9BX80	Gene names	ABCC11, MRP8
Domain Architecture	No domain graphic available
Description	ATP-binding cassette transporter sub-family C member 11 (Multidrug resistance-associated protein 8).

MRP7_MOUSE
θ value	8.06329e-33 (rank : 34)	NC score	0.828701 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R4P9, Q3TCQ0, Q3V0D1, Q8R4S1	Gene names	Abcc10, Mrp7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

ABCC9_MOUSE
θ value	1.98606e-31 (rank : 35)	NC score	0.814297 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

MRP4_HUMAN
θ value	3.3877e-31 (rank : 36)	NC score	0.824708 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	90
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

ABCC9_HUMAN
θ value	5.77852e-31 (rank : 37)	NC score	0.809274 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	108	Shared Neighborhood Hits	89
SwissProt Accessions	O60706, O60707	Gene names	ABCC9, SUR2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

CFTR_MOUSE
θ value	3.39556e-23 (rank : 38)	NC score	0.801702 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	115	Shared Neighborhood Hits	87
SwissProt Accessions	P26361, Q63893, Q63894, Q9JKQ6	Gene names	Cftr, Abcc7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

CFTR_HUMAN
θ value	4.43474e-23 (rank : 39)	NC score	0.802116 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	104	Shared Neighborhood Hits	88
SwissProt Accessions	P13569	Gene names	CFTR, ABCC7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

ABCA1_HUMAN
θ value	2.27762e-19 (rank : 40)	NC score	0.608517 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

ABCA5_HUMAN
θ value	2.27762e-19 (rank : 41)	NC score	0.625062 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	146	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA5_MOUSE
θ value	2.27762e-19 (rank : 42)	NC score	0.623823 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA1_MOUSE
θ value	3.88503e-19 (rank : 43)	NC score	0.609265 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

ABCA7_HUMAN
θ value	3.28887e-18 (rank : 44)	NC score	0.602097 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	144	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ABCA3_HUMAN
θ value	5.60996e-18 (rank : 45)	NC score	0.657842 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	92
SwissProt Accessions	Q99758, Q54A95, Q92473	Gene names	ABCA3, ABC3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter).

ABCA4_MOUSE
θ value	1.63225e-17 (rank : 46)	NC score	0.610519 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	126	Shared Neighborhood Hits	90
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

ABCA3_MOUSE
θ value	2.13179e-17 (rank : 47)	NC score	0.647566 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	90
SwissProt Accessions	Q8R420	Gene names	Abca3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3.

ABCAD_HUMAN
θ value	2.13179e-17 (rank : 48)	NC score	0.594653 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	207	Shared Neighborhood Hits	85
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCA6_HUMAN
θ value	2.7842e-17 (rank : 49)	NC score	0.595430 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N139, Q6NSH9, Q8N856, Q8WWZ6	Gene names	ABCA6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA9_MOUSE
θ value	2.7842e-17 (rank : 50)	NC score	0.594827 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCA7_MOUSE
θ value	3.63628e-17 (rank : 51)	NC score	0.599678 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	88
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

ABCA4_HUMAN
θ value	6.20254e-17 (rank : 52)	NC score	0.609397 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	116	Shared Neighborhood Hits	91
SwissProt Accessions	P78363, O15112, O60438, O60915	Gene names	ABCA4, ABCR
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein).

ABCA2_HUMAN
θ value	1.058e-16 (rank : 53)	NC score	0.600203 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	143	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA2_MOUSE
θ value	2.35696e-16 (rank : 54)	NC score	0.600573 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA6_MOUSE
θ value	4.02038e-16 (rank : 55)	NC score	0.589603 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA9_HUMAN
θ value	1.16975e-15 (rank : 56)	NC score	0.578491 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCAC_HUMAN
θ value	1.99529e-15 (rank : 57)	NC score	0.606893 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	123	Shared Neighborhood Hits	90
SwissProt Accessions	Q86UK0, Q8IZW6, Q96JT3, Q9Y4M5	Gene names	ABCA12, ABC12
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12).

ABCG5_MOUSE
θ value	5.8054e-15 (rank : 58)	NC score	0.704130 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	84
SwissProt Accessions	Q99PE8	Gene names	Abcg5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABC8B_MOUSE
θ value	7.58209e-15 (rank : 59)	NC score	0.589062 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	124	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

ABCG1_MOUSE
θ value	7.58209e-15 (rank : 60)	NC score	0.686274 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	89
SwissProt Accessions	Q64343	Gene names	Abcg1, Abc8, Wht1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG1_HUMAN
θ value	1.29331e-14 (rank : 61)	NC score	0.680091 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P45844, Q86SU8, Q96L76, Q9BXK6, Q9BXK7, Q9BXK8, Q9BXK9, Q9BXL0, Q9BXL1, Q9BXL2, Q9BXL3, Q9BXL4	Gene names	ABCG1, ABC8, WHT1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABC8A_MOUSE
θ value	2.20605e-14 (rank : 62)	NC score	0.587428 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	115	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

ABCAD_MOUSE
θ value	4.91457e-14 (rank : 63)	NC score	0.589492 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	150	Shared Neighborhood Hits	87
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCAA_HUMAN
θ value	1.86753e-13 (rank : 64)	NC score	0.585694 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	123	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

ABCG5_HUMAN
θ value	7.09661e-13 (rank : 65)	NC score	0.676803 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H222	Gene names	ABCG5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCG2_HUMAN
θ value	7.84624e-12 (rank : 66)	NC score	0.644206 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UNQ0, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64, Q8IX16, Q96LD6, Q96TA8, Q9BY73, Q9NUS0	Gene names	ABCG2, ABCP, BCRP, BCRP1, MXR
Domain Architecture
Description	ATP-binding cassette sub-family G member 2 (Placenta-specific ATP- binding cassette transporter) (Breast cancer resistance protein) (Mitoxantrone resistance-associated protein) (CDw338 antigen).

ABCG8_HUMAN
θ value	1.02475e-11 (rank : 67)	NC score	0.673008 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H221	Gene names	ABCG8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCG4_HUMAN
θ value	1.33837e-11 (rank : 68)	NC score	0.633522 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	90	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H172	Gene names	ABCG4, WHITE2
Domain Architecture
Description	ATP-binding cassette sub-family G member 4.

ABCG8_MOUSE
θ value	1.33837e-11 (rank : 69)	NC score	0.658212 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBM0	Gene names	Abcg8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCD3_HUMAN
θ value	3.89403e-11 (rank : 70)	NC score	0.589275 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	85	Shared Neighborhood Hits	74
SwissProt Accessions	P28288, Q15271, Q9H529	Gene names	ABCD3, PMP70, PXMP1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70).

ABCG2_MOUSE
θ value	8.67504e-11 (rank : 71)	NC score	0.641512 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TMS5, Q9R004, Q9Z1T0	Gene names	Abcg2, Abcp, Bcrp1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein 1 homolog).

ABCD4_MOUSE
θ value	1.9326e-10 (rank : 72)	NC score	0.615898 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	82
SwissProt Accessions	O89016	Gene names	Abcd4, Pxmp1l
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCD4_HUMAN
θ value	5.62301e-10 (rank : 73)	NC score	0.639242 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	85
SwissProt Accessions	O14678	Gene names	ABCD4, PXMP1L
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCD1_HUMAN
θ value	7.34386e-10 (rank : 74)	NC score	0.548401 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	79
SwissProt Accessions	P33897, Q6GTZ2	Gene names	ABCD1, ALD
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCD2_HUMAN
θ value	7.34386e-10 (rank : 75)	NC score	0.527458 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	87	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UBJ2, Q13210	Gene names	ABCD2, ALD1, ALDL1, ALDR, ALDRP
Domain Architecture
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein) (hALDR) (Adrenoleukodystrophy-like 1).

ABCD1_MOUSE
θ value	3.64472e-09 (rank : 76)	NC score	0.534010 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	79
SwissProt Accessions	P48410, Q9QY41, Q9QZ32	Gene names	Abcd1, Ald, Aldgh
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCD2_MOUSE
θ value	3.64472e-09 (rank : 77)	NC score	0.532250 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	Q61285, Q8BQ63, Q8C4B6	Gene names	Abcd2, Aldr
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein).

ABCF1_MOUSE
θ value	1.38499e-08 (rank : 78)	NC score	0.538163 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	321	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ABCD3_MOUSE
θ value	2.36244e-08 (rank : 79)	NC score	0.566211 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	83	Shared Neighborhood Hits	77
SwissProt Accessions	P55096	Gene names	Abcd3, Pmp70, Pxmp1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70) (PMP68).

ABCA8_HUMAN
θ value	3.08544e-08 (rank : 80)	NC score	0.540696 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	O94911, Q86WW0	Gene names	ABCA8, KIAA0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8.

ABCF1_HUMAN
θ value	4.0297e-08 (rank : 81)	NC score	0.533408 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	343	Shared Neighborhood Hits	93
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

ABCF3_HUMAN
θ value	2.21117e-06 (rank : 82)	NC score	0.527352 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NUQ8, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8	Gene names	ABCF3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCF2_HUMAN
θ value	1.43324e-05 (rank : 83)	NC score	0.522090 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UG63, O60864, Q96TE8	Gene names	ABCF2
Domain Architecture
Description	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2).

ABCF2_MOUSE
θ value	1.43324e-05 (rank : 84)	NC score	0.525310 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

ABCF3_MOUSE
θ value	1.43324e-05 (rank : 85)	NC score	0.538365 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	126	Shared Neighborhood Hits	95
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCE1_HUMAN
θ value	7.1131e-05 (rank : 86)	NC score	0.571560 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	114	Shared Neighborhood Hits	93
SwissProt Accessions	P61221, O88793, Q13181, Q13864, Q6NR76, Q96AL0, Q96B10, Q99K66	Gene names	ABCE1, RLI
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5' oligoadenylate-binding protein) (HuHP68).

ABCE1_MOUSE
θ value	7.1131e-05 (rank : 87)	NC score	0.571560 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	114	Shared Neighborhood Hits	93
SwissProt Accessions	P61222, O88793, Q13181, Q13864, Q96AL0, Q96B10, Q99K66	Gene names	Abce1, Rli
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I).

ABCG3_MOUSE
θ value	0.00665767 (rank : 88)	NC score	0.373166 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	67	Shared Neighborhood Hits	58
SwissProt Accessions	Q99P81	Gene names	Abcg3
Domain Architecture
Description	ATP-binding cassette sub-family G member 3.

MDN1_HUMAN
θ value	0.279714 (rank : 89)	NC score	0.091800 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	662	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

PAR14_MOUSE
θ value	1.06291 (rank : 90)	NC score	0.007989 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

CROCC_MOUSE
θ value	1.38821 (rank : 91)	NC score	-0.002813 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	1460	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

RAD50_MOUSE
θ value	1.38821 (rank : 92)	NC score	0.024134 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	1366	Shared Neighborhood Hits	46
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SMC3_HUMAN
θ value	1.38821 (rank : 93)	NC score	0.022280 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	1186	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	1.38821 (rank : 94)	NC score	0.022285 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	1187	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

RAD50_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.022076 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	1317	Shared Neighborhood Hits	43
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

DHX35_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.013581 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

IFT81_MOUSE
θ value	4.03905 (rank : 97)	NC score	-0.002160 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	959	Shared Neighborhood Hits	9
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

FEZ2_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.005053 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q6TYB5	Gene names	Fez2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

LSHR_MOUSE
θ value	5.27518 (rank : 99)	NC score	-0.003300 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	686	Shared Neighborhood Hits	2
SwissProt Accessions	P30730	Gene names	Lhcgr, Lhr
Domain Architecture
Description	Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH- R) (Luteinizing hormone receptor).

RAD17_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.031326 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NXW6, O88934, O89024	Gene names	Rad17
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17.

SMC2_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.019016 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	1405	Shared Neighborhood Hits	35
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC2_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.023729 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	1131	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

AG10A_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.005993 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q5BKT4, Q6NS98, Q96DU0, Q96SM6	Gene names	ALG10, ALG10A
Domain Architecture	No domain graphic available
Description	Alpha-1,2-glucosyltransferase ALG10-A (EC 2.4.1.-) (Alpha-2- glucosyltransferase ALG10-A) (Asparagine-linked glycosylation protein 10 homolog A).

LHR2A_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.005007 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

LRRK2_MOUSE
θ value	6.88961 (rank : 105)	NC score	-0.004788 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	1359	Shared Neighborhood Hits	13
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

PAK2_MOUSE
θ value	6.88961 (rank : 106)	NC score	-0.007238 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	858	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIN4	Gene names	Pak2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2).

PAPS2_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.003811 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	O88428, Q9Z274	Gene names	Papss2, Atpsk2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

SEPT2_MOUSE
θ value	6.88961 (rank : 108)	NC score	0.007821 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	P42208, Q3U9Y5	Gene names	Sept2, Nedd-5, Nedd5
Domain Architecture
Description	Septin-2 (Protein NEDD5) (Neural precursor cell expressed developmentally down-regulated protein 5).

LAMA5_HUMAN
θ value	8.99809 (rank : 109)	NC score	-0.003804 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	976	Shared Neighborhood Hits	8
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

SEPT2_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.007083 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	Q15019, Q14132, Q8IUK9, Q96CB0	Gene names	SEPT2, DIFF6, KIAA0158, NEDD5
Domain Architecture
Description	Septin-2 (Protein NEDD5).

VATA1_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.006546 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P50516	Gene names	Atp6v1a, Atp6a1, Atp6a2, Atp6v1a1
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1).

VAV3_HUMAN
θ value	8.99809 (rank : 112)	NC score	-0.002514 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	398	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

ABCCD_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.365882 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NSE7, Q8N6A4, Q8N6A5	Gene names	ABCC13, C21orf73, PRED6
Domain Architecture
Description	Putative ATP-binding cassette transporter C13.

Hits sorted by NC score

MDR1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_MOUSE
NC score	0.998332 (rank : 2)	θ value	0 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	106	Shared Neighborhood Hits	96
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

MDR2_MOUSE
NC score	0.997826 (rank : 3)	θ value	0 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	108	Shared Neighborhood Hits	100
SwissProt Accessions	P21440, Q6LCL9	Gene names	Abcb4, Mdr2, Pgy-2, Pgy2
Domain Architecture
Description	Multidrug resistance protein 2 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 2).

MDR3_HUMAN
NC score	0.997627 (rank : 4)	θ value	0 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	P21439, Q14813	Gene names	ABCB4, MDR3, PGY3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 3).

MDR1_MOUSE
NC score	0.997469 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

ABCB5_HUMAN
NC score	0.993697 (rank : 6)	θ value	0 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	96
SwissProt Accessions	Q2M3G0, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1	Gene names	ABCB5
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family B member 5 (P-glycoprotein ABCB5) (ABCB5 P-gp).

ABCBB_HUMAN
NC score	0.993593 (rank : 7)	θ value	0 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	89
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

ABCBB_MOUSE
NC score	0.993155 (rank : 8)	θ value	0 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	97	Shared Neighborhood Hits	90
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

ABCB8_HUMAN
NC score	0.962057 (rank : 9)	θ value	3.11973e-85 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NUT2, O95787	Gene names	ABCB8, MABC1
Domain Architecture
Description	ATP-binding cassette sub-family B member 8, mitochondrial precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1).

ABCBA_HUMAN
NC score	0.961039 (rank : 10)	θ value	3.9282e-96 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	91
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

ABCBA_MOUSE
NC score	0.960874 (rank : 11)	θ value	5.1304e-96 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	97	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JI39, Q542P7, Q9D0C7	Gene names	Abcb10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein).

ABCB6_HUMAN
NC score	0.947489 (rank : 12)	θ value	2.56992e-63 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NP58, O75542	Gene names	ABCB6, MTABC3
Domain Architecture
Description	ATP-binding cassette sub-family B member 6, mitochondrial precursor (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (ABC transporter umat).

ABCB9_HUMAN
NC score	0.947399 (rank : 13)	θ value	1.65422e-86 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NP78, Q96AB1, Q9P208	Gene names	ABCB9, KIAA1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9).

ABCB9_MOUSE
NC score	0.947334 (rank : 14)	θ value	3.33315e-87 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	93
SwissProt Accessions	Q9JJ59, Q8CHA1, Q9D212, Q9JIN1	Gene names	Abcb9, Kiaa1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9).

TAP1_MOUSE
NC score	0.943098 (rank : 15)	θ value	1.66191e-70 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	89
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

TAP2_MOUSE
NC score	0.942985 (rank : 16)	θ value	2.3998e-69 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	93	Shared Neighborhood Hits	87
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

TAP1_HUMAN
NC score	0.942700 (rank : 17)	θ value	1.71981e-67 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	91
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

ABCB7_HUMAN
NC score	0.941532 (rank : 18)	θ value	1.41344e-53 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	92
SwissProt Accessions	O75027, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01	Gene names	ABCB7, ABC7
Domain Architecture
Description	ATP-binding cassette sub-family B member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein).

TAP2_HUMAN
NC score	0.940738 (rank : 19)	θ value	1.04338e-64 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

MRP5_HUMAN
NC score	0.847851 (rank : 20)	θ value	5.7252e-63 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

MRP5_MOUSE
NC score	0.846463 (rank : 21)	θ value	2.03627e-60 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	88
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

MRP2_HUMAN
NC score	0.841323 (rank : 22)	θ value	8.26713e-62 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	90
SwissProt Accessions	Q92887, Q14022, Q92500, Q92798, Q99663, Q9UMS2	Gene names	ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein).

MRP7_HUMAN
NC score	0.832494 (rank : 23)	θ value	1.46948e-34 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q5T3U5, Q8NHX7, Q9H7N2, Q9NXY3, Q9UF48	Gene names	ABCC10, MRP7, SIMRP7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

MRP9_MOUSE
NC score	0.831445 (rank : 24)	θ value	9.20422e-37 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MRP7_MOUSE
NC score	0.828701 (rank : 25)	θ value	8.06329e-33 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	99	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R4P9, Q3TCQ0, Q3V0D1, Q8R4S1	Gene names	Abcc10, Mrp7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

MRP6_HUMAN
NC score	0.827483 (rank : 26)	θ value	4.70527e-49 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	90
SwissProt Accessions	O95255, P78420, Q9UMZ7	Gene names	ABCC6, ARA, MRP6
Domain Architecture
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E).

MRP4_HUMAN
NC score	0.824708 (rank : 27)	θ value	3.3877e-31 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	90
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

ABCCB_HUMAN
NC score	0.823061 (rank : 28)	θ value	3.27365e-34 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	118	Shared Neighborhood Hits	89
SwissProt Accessions	Q96J66, Q8TDJ0, Q96JA6, Q9BX80	Gene names	ABCC11, MRP8
Domain Architecture	No domain graphic available
Description	ATP-binding cassette transporter sub-family C member 11 (Multidrug resistance-associated protein 8).

MRP3_HUMAN
NC score	0.821763 (rank : 29)	θ value	2.84797e-54 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	125	Shared Neighborhood Hits	93
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

MRP6_MOUSE
NC score	0.820909 (rank : 30)	θ value	1.51363e-47 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

MRP9_HUMAN
NC score	0.818358 (rank : 31)	θ value	1.20211e-36 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	114	Shared Neighborhood Hits	88
SwissProt Accessions	Q96J65, Q49AL2, Q8TAF0, Q8TEY2	Gene names	ABCC12, MRP9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MRP1_MOUSE
NC score	0.817033 (rank : 32)	θ value	3.14151e-61 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	90
SwissProt Accessions	O35379	Gene names	Abcc1, Abcc1a, Abcc1b, Mdrap, Mrp
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP2_MOUSE
NC score	0.815805 (rank : 33)	θ value	8.32485e-38 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

ABCC9_MOUSE
NC score	0.814297 (rank : 34)	θ value	1.98606e-31 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

MRP1_HUMAN
NC score	0.813477 (rank : 35)	θ value	1.08726e-37 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	90
SwissProt Accessions	P33527, O14819, O43333, P78419, Q59GI9, Q9UQ97, Q9UQ99, Q9UQA0	Gene names	ABCC1, MRP, MRP1
Domain Architecture
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

ABCC8_HUMAN
NC score	0.813382 (rank : 36)	θ value	1.32293e-51 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	118	Shared Neighborhood Hits	88
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

ABCC9_HUMAN
NC score	0.809274 (rank : 37)	θ value	5.77852e-31 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	108	Shared Neighborhood Hits	89
SwissProt Accessions	O60706, O60707	Gene names	ABCC9, SUR2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

CFTR_HUMAN
NC score	0.802116 (rank : 38)	θ value	4.43474e-23 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	104	Shared Neighborhood Hits	88
SwissProt Accessions	P13569	Gene names	CFTR, ABCC7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

CFTR_MOUSE
NC score	0.801702 (rank : 39)	θ value	3.39556e-23 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	115	Shared Neighborhood Hits	87
SwissProt Accessions	P26361, Q63893, Q63894, Q9JKQ6	Gene names	Cftr, Abcc7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

ABCG5_MOUSE
NC score	0.704130 (rank : 40)	θ value	5.8054e-15 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	84
SwissProt Accessions	Q99PE8	Gene names	Abcg5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCG1_MOUSE
NC score	0.686274 (rank : 41)	θ value	7.58209e-15 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	100	Shared Neighborhood Hits	89
SwissProt Accessions	Q64343	Gene names	Abcg1, Abc8, Wht1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG1_HUMAN
NC score	0.680091 (rank : 42)	θ value	1.29331e-14 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	P45844, Q86SU8, Q96L76, Q9BXK6, Q9BXK7, Q9BXK8, Q9BXK9, Q9BXL0, Q9BXL1, Q9BXL2, Q9BXL3, Q9BXL4	Gene names	ABCG1, ABC8, WHT1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG5_HUMAN
NC score	0.676803 (rank : 43)	θ value	7.09661e-13 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	88
SwissProt Accessions	Q9H222	Gene names	ABCG5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCG8_HUMAN
NC score	0.673008 (rank : 44)	θ value	1.02475e-11 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H221	Gene names	ABCG8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCG8_MOUSE
NC score	0.658212 (rank : 45)	θ value	1.33837e-11 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	89	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBM0	Gene names	Abcg8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCA3_HUMAN
NC score	0.657842 (rank : 46)	θ value	5.60996e-18 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	92
SwissProt Accessions	Q99758, Q54A95, Q92473	Gene names	ABCA3, ABC3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter).

ABCA3_MOUSE
NC score	0.647566 (rank : 47)	θ value	2.13179e-17 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	90
SwissProt Accessions	Q8R420	Gene names	Abca3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3.

ABCG2_HUMAN
NC score	0.644206 (rank : 48)	θ value	7.84624e-12 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UNQ0, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64, Q8IX16, Q96LD6, Q96TA8, Q9BY73, Q9NUS0	Gene names	ABCG2, ABCP, BCRP, BCRP1, MXR
Domain Architecture
Description	ATP-binding cassette sub-family G member 2 (Placenta-specific ATP- binding cassette transporter) (Breast cancer resistance protein) (Mitoxantrone resistance-associated protein) (CDw338 antigen).

ABCG2_MOUSE
NC score	0.641512 (rank : 49)	θ value	8.67504e-11 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TMS5, Q9R004, Q9Z1T0	Gene names	Abcg2, Abcp, Bcrp1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein 1 homolog).

ABCD4_HUMAN
NC score	0.639242 (rank : 50)	θ value	5.62301e-10 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	95	Shared Neighborhood Hits	85
SwissProt Accessions	O14678	Gene names	ABCD4, PXMP1L
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCG4_HUMAN
NC score	0.633522 (rank : 51)	θ value	1.33837e-11 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	90	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H172	Gene names	ABCG4, WHITE2
Domain Architecture
Description	ATP-binding cassette sub-family G member 4.

ABCA5_HUMAN
NC score	0.625062 (rank : 52)	θ value	2.27762e-19 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	146	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA5_MOUSE
NC score	0.623823 (rank : 53)	θ value	2.27762e-19 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCD4_MOUSE
NC score	0.615898 (rank : 54)	θ value	1.9326e-10 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	82
SwissProt Accessions	O89016	Gene names	Abcd4, Pxmp1l
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCA4_MOUSE
NC score	0.610519 (rank : 55)	θ value	1.63225e-17 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	126	Shared Neighborhood Hits	90
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

ABCA4_HUMAN
NC score	0.609397 (rank : 56)	θ value	6.20254e-17 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	116	Shared Neighborhood Hits	91
SwissProt Accessions	P78363, O15112, O60438, O60915	Gene names	ABCA4, ABCR
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein).

ABCA1_MOUSE
NC score	0.609265 (rank : 57)	θ value	3.88503e-19 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

ABCA1_HUMAN
NC score	0.608517 (rank : 58)	θ value	2.27762e-19 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

ABCAC_HUMAN
NC score	0.606893 (rank : 59)	θ value	1.99529e-15 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	123	Shared Neighborhood Hits	90
SwissProt Accessions	Q86UK0, Q8IZW6, Q96JT3, Q9Y4M5	Gene names	ABCA12, ABC12
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12).

ABCA7_HUMAN
NC score	0.602097 (rank : 60)	θ value	3.28887e-18 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	144	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ABCA2_MOUSE
NC score	0.600573 (rank : 61)	θ value	2.35696e-16 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA2_HUMAN
NC score	0.600203 (rank : 62)	θ value	1.058e-16 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	143	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA7_MOUSE
NC score	0.599678 (rank : 63)	θ value	3.63628e-17 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	88
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

ABCA6_HUMAN
NC score	0.595430 (rank : 64)	θ value	2.7842e-17 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	91
SwissProt Accessions	Q8N139, Q6NSH9, Q8N856, Q8WWZ6	Gene names	ABCA6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA9_MOUSE
NC score	0.594827 (rank : 65)	θ value	2.7842e-17 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCAD_HUMAN
NC score	0.594653 (rank : 66)	θ value	2.13179e-17 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	207	Shared Neighborhood Hits	85
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCA6_MOUSE
NC score	0.589603 (rank : 67)	θ value	4.02038e-16 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCAD_MOUSE
NC score	0.589492 (rank : 68)	θ value	4.91457e-14 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	150	Shared Neighborhood Hits	87
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCD3_HUMAN
NC score	0.589275 (rank : 69)	θ value	3.89403e-11 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	85	Shared Neighborhood Hits	74
SwissProt Accessions	P28288, Q15271, Q9H529	Gene names	ABCD3, PMP70, PXMP1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70).

ABC8B_MOUSE
NC score	0.589062 (rank : 70)	θ value	7.58209e-15 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	124	Shared Neighborhood Hits	89
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

ABC8A_MOUSE
NC score	0.587428 (rank : 71)	θ value	2.20605e-14 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	115	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

ABCAA_HUMAN
NC score	0.585694 (rank : 72)	θ value	1.86753e-13 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	123	Shared Neighborhood Hits	90
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

ABCA9_HUMAN
NC score	0.578491 (rank : 73)	θ value	1.16975e-15 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCE1_HUMAN
NC score	0.571560 (rank : 74)	θ value	7.1131e-05 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	114	Shared Neighborhood Hits	93
SwissProt Accessions	P61221, O88793, Q13181, Q13864, Q6NR76, Q96AL0, Q96B10, Q99K66	Gene names	ABCE1, RLI
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5' oligoadenylate-binding protein) (HuHP68).

ABCE1_MOUSE
NC score	0.571560 (rank : 75)	θ value	7.1131e-05 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	114	Shared Neighborhood Hits	93
SwissProt Accessions	P61222, O88793, Q13181, Q13864, Q96AL0, Q96B10, Q99K66	Gene names	Abce1, Rli
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I).

ABCD3_MOUSE
NC score	0.566211 (rank : 76)	θ value	2.36244e-08 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	83	Shared Neighborhood Hits	77
SwissProt Accessions	P55096	Gene names	Abcd3, Pmp70, Pxmp1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70) (PMP68).

ABCD1_HUMAN
NC score	0.548401 (rank : 77)	θ value	7.34386e-10 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	91	Shared Neighborhood Hits	79
SwissProt Accessions	P33897, Q6GTZ2	Gene names	ABCD1, ALD
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCA8_HUMAN
NC score	0.540696 (rank : 78)	θ value	3.08544e-08 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	O94911, Q86WW0	Gene names	ABCA8, KIAA0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8.

ABCF3_MOUSE
NC score	0.538365 (rank : 79)	θ value	1.43324e-05 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	126	Shared Neighborhood Hits	95
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCF1_MOUSE
NC score	0.538163 (rank : 80)	θ value	1.38499e-08 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	321	Shared Neighborhood Hits	93
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ABCD1_MOUSE
NC score	0.534010 (rank : 81)	θ value	3.64472e-09 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	79
SwissProt Accessions	P48410, Q9QY41, Q9QZ32	Gene names	Abcd1, Ald, Aldgh
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCF1_HUMAN
NC score	0.533408 (rank : 82)	θ value	4.0297e-08 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	343	Shared Neighborhood Hits	93
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

ABCD2_MOUSE
NC score	0.532250 (rank : 83)	θ value	3.64472e-09 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	88	Shared Neighborhood Hits	77
SwissProt Accessions	Q61285, Q8BQ63, Q8C4B6	Gene names	Abcd2, Aldr
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein).

ABCD2_HUMAN
NC score	0.527458 (rank : 84)	θ value	7.34386e-10 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	87	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UBJ2, Q13210	Gene names	ABCD2, ALD1, ALDL1, ALDR, ALDRP
Domain Architecture
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein) (hALDR) (Adrenoleukodystrophy-like 1).

ABCF3_HUMAN
NC score	0.527352 (rank : 85)	θ value	2.21117e-06 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NUQ8, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8	Gene names	ABCF3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCF2_MOUSE
NC score	0.525310 (rank : 86)	θ value	1.43324e-05 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

ABCF2_HUMAN
NC score	0.522090 (rank : 87)	θ value	1.43324e-05 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UG63, O60864, Q96TE8	Gene names	ABCF2
Domain Architecture
Description	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2).

ABCG3_MOUSE
NC score	0.373166 (rank : 88)	θ value	0.00665767 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	67	Shared Neighborhood Hits	58
SwissProt Accessions	Q99P81	Gene names	Abcg3
Domain Architecture
Description	ATP-binding cassette sub-family G member 3.

ABCCD_HUMAN
NC score	0.365882 (rank : 89)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	112	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NSE7, Q8N6A4, Q8N6A5	Gene names	ABCC13, C21orf73, PRED6
Domain Architecture
Description	Putative ATP-binding cassette transporter C13.

MDN1_HUMAN
NC score	0.091800 (rank : 90)	θ value	0.279714 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	662	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RAD17_MOUSE
NC score	0.031326 (rank : 91)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NXW6, O88934, O89024	Gene names	Rad17
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17.

RAD50_MOUSE
NC score	0.024134 (rank : 92)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	1366	Shared Neighborhood Hits	46
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SMC2_MOUSE
NC score	0.023729 (rank : 93)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	1131	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SMC3_MOUSE
NC score	0.022285 (rank : 94)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	1187	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.022280 (rank : 95)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	1186	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

RAD50_HUMAN
NC score	0.022076 (rank : 96)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	1317	Shared Neighborhood Hits	43
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

SMC2_HUMAN
NC score	0.019016 (rank : 97)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	1405	Shared Neighborhood Hits	35
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

DHX35_HUMAN
NC score	0.013581 (rank : 98)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	46	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H5Z1, Q5THR0, Q9H4H7, Q9H6T6	Gene names	DHX35, C20orf15, DDX35
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX35 (EC 3.6.1.-) (DEAH box protein 35).

PAR14_MOUSE
NC score	0.007989 (rank : 99)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

SEPT2_MOUSE
NC score	0.007821 (rank : 100)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	P42208, Q3U9Y5	Gene names	Sept2, Nedd-5, Nedd5
Domain Architecture
Description	Septin-2 (Protein NEDD5) (Neural precursor cell expressed developmentally down-regulated protein 5).

SEPT2_HUMAN
NC score	0.007083 (rank : 101)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	9
SwissProt Accessions	Q15019, Q14132, Q8IUK9, Q96CB0	Gene names	SEPT2, DIFF6, KIAA0158, NEDD5
Domain Architecture
Description	Septin-2 (Protein NEDD5).

VATA1_MOUSE
NC score	0.006546 (rank : 102)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P50516	Gene names	Atp6v1a, Atp6a1, Atp6a2, Atp6v1a1
Domain Architecture
Description	Vacuolar ATP synthase catalytic subunit A, ubiquitous isoform (EC 3.6.3.14) (V-ATPase subunit A 1) (Vacuolar proton pump alpha subunit 1) (V-ATPase 69 kDa subunit 1).

AG10A_HUMAN
NC score	0.005993 (rank : 103)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q5BKT4, Q6NS98, Q96DU0, Q96SM6	Gene names	ALG10, ALG10A
Domain Architecture	No domain graphic available
Description	Alpha-1,2-glucosyltransferase ALG10-A (EC 2.4.1.-) (Alpha-2- glucosyltransferase ALG10-A) (Asparagine-linked glycosylation protein 10 homolog A).

FEZ2_MOUSE
NC score	0.005053 (rank : 104)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q6TYB5	Gene names	Fez2
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 2 (Zygin-2) (Zygin II).

LHR2A_HUMAN
NC score	0.005007 (rank : 105)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

PAPS2_MOUSE
NC score	0.003811 (rank : 106)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	O88428, Q9Z274	Gene names	Papss2, Atpsk2
Domain Architecture
Description	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (PAPS synthetase 2) (PAPSS 2) (Sulfurylase kinase 2) (SK2) (SK 2) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (Sulfate adenylate transferase) (SAT) (ATP-sulfurylase); Adenylyl-sulfate kinase (EC 2.7.1.25) (Adenylylsulfate 3'-phosphotransferase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (3'- phosphoadenosine-5'-phosphosulfate synthetase)].

IFT81_MOUSE
NC score	-0.002160 (rank : 107)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	959	Shared Neighborhood Hits	9
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

VAV3_HUMAN
NC score	-0.002514 (rank : 108)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	398	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

CROCC_MOUSE
NC score	-0.002813 (rank : 109)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	1460	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

LSHR_MOUSE
NC score	-0.003300 (rank : 110)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	686	Shared Neighborhood Hits	2
SwissProt Accessions	P30730	Gene names	Lhcgr, Lhr
Domain Architecture
Description	Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH- R) (Luteinizing hormone receptor).

LAMA5_HUMAN
NC score	-0.003804 (rank : 111)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	976	Shared Neighborhood Hits	8
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LRRK2_MOUSE
NC score	-0.004788 (rank : 112)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	1359	Shared Neighborhood Hits	13
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

PAK2_MOUSE
NC score	-0.007238 (rank : 113)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	858	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CIN4	Gene names	Pak2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2).