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Network neighborhood for query Sequence : ABCA5_MOUSE

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ABCA5_MOUSE
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ABC8A_MOUSE
θ value	0 (rank : 1)	NC score	0.987108 (rank : 8)
Query Neighborhood Hits	137	Target Neighborhood Hits	115	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

ABC8B_MOUSE
θ value	0 (rank : 2)	NC score	0.987129 (rank : 7)
Query Neighborhood Hits	137	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

ABCA5_HUMAN
θ value	0 (rank : 3)	NC score	0.998319 (rank : 2)
Query Neighborhood Hits	137	Target Neighborhood Hits	146	Shared Neighborhood Hits	103
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA5_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	137	Target Neighborhood Hits	137	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA6_HUMAN
θ value	0 (rank : 5)	NC score	0.988369 (rank : 3)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N139, Q6NSH9, Q8N856, Q8WWZ6	Gene names	ABCA6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA6_MOUSE
θ value	0 (rank : 6)	NC score	0.987943 (rank : 5)
Query Neighborhood Hits	137	Target Neighborhood Hits	111	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA8_HUMAN
θ value	0 (rank : 7)	NC score	0.981485 (rank : 10)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	88
SwissProt Accessions	O94911, Q86WW0	Gene names	ABCA8, KIAA0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8.

ABCA9_HUMAN
θ value	0 (rank : 8)	NC score	0.986745 (rank : 9)
Query Neighborhood Hits	137	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCA9_MOUSE
θ value	0 (rank : 9)	NC score	0.988033 (rank : 4)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCAA_HUMAN
θ value	0 (rank : 10)	NC score	0.987237 (rank : 6)
Query Neighborhood Hits	137	Target Neighborhood Hits	123	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

ABCA3_MOUSE
θ value	2.54619e-95 (rank : 11)	NC score	0.929913 (rank : 11)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R420	Gene names	Abca3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3.

ABCA3_HUMAN
θ value	2.46618e-90 (rank : 12)	NC score	0.922855 (rank : 12)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q99758, Q54A95, Q92473	Gene names	ABCA3, ABC3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter).

ABCA1_MOUSE
θ value	1.49966e-79 (rank : 13)	NC score	0.875958 (rank : 16)
Query Neighborhood Hits	137	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

ABCA2_HUMAN
θ value	6.30065e-78 (rank : 14)	NC score	0.893539 (rank : 13)
Query Neighborhood Hits	137	Target Neighborhood Hits	143	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCAC_HUMAN
θ value	2.64714e-76 (rank : 15)	NC score	0.887514 (rank : 15)
Query Neighborhood Hits	137	Target Neighborhood Hits	123	Shared Neighborhood Hits	89
SwissProt Accessions	Q86UK0, Q8IZW6, Q96JT3, Q9Y4M5	Gene names	ABCA12, ABC12
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12).

ABCA2_MOUSE
θ value	3.45727e-76 (rank : 16)	NC score	0.889057 (rank : 14)
Query Neighborhood Hits	137	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCAD_MOUSE
θ value	1.89707e-74 (rank : 17)	NC score	0.871854 (rank : 20)
Query Neighborhood Hits	137	Target Neighborhood Hits	150	Shared Neighborhood Hits	86
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCA1_HUMAN
θ value	1.60597e-73 (rank : 18)	NC score	0.873244 (rank : 18)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	88
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

ABCAD_HUMAN
θ value	5.71191e-71 (rank : 19)	NC score	0.871774 (rank : 21)
Query Neighborhood Hits	137	Target Neighborhood Hits	207	Shared Neighborhood Hits	86
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCA4_MOUSE
θ value	2.4834e-66 (rank : 20)	NC score	0.869061 (rank : 23)
Query Neighborhood Hits	137	Target Neighborhood Hits	126	Shared Neighborhood Hits	89
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

ABCA7_HUMAN
θ value	7.98882e-65 (rank : 21)	NC score	0.874173 (rank : 17)
Query Neighborhood Hits	137	Target Neighborhood Hits	144	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ABCA4_HUMAN
θ value	3.96481e-64 (rank : 22)	NC score	0.870103 (rank : 22)
Query Neighborhood Hits	137	Target Neighborhood Hits	116	Shared Neighborhood Hits	89
SwissProt Accessions	P78363, O15112, O60438, O60915	Gene names	ABCA4, ABCR
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein).

ABCA7_MOUSE
θ value	5.17823e-64 (rank : 23)	NC score	0.872163 (rank : 19)
Query Neighborhood Hits	137	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

MDR1_HUMAN
θ value	2.27762e-19 (rank : 24)	NC score	0.623823 (rank : 42)
Query Neighborhood Hits	137	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_MOUSE
θ value	2.27762e-19 (rank : 25)	NC score	0.625794 (rank : 41)
Query Neighborhood Hits	137	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

MDR2_MOUSE
θ value	6.62687e-19 (rank : 26)	NC score	0.629549 (rank : 39)
Query Neighborhood Hits	137	Target Neighborhood Hits	108	Shared Neighborhood Hits	89
SwissProt Accessions	P21440, Q6LCL9	Gene names	Abcb4, Mdr2, Pgy-2, Pgy2
Domain Architecture
Description	Multidrug resistance protein 2 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 2).

MDR1_MOUSE
θ value	1.47631e-18 (rank : 27)	NC score	0.626069 (rank : 40)
Query Neighborhood Hits	137	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_HUMAN
θ value	4.29542e-18 (rank : 28)	NC score	0.622919 (rank : 43)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	89
SwissProt Accessions	P21439, Q14813	Gene names	ABCB4, MDR3, PGY3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 3).

ABCBA_HUMAN
θ value	5.60996e-18 (rank : 29)	NC score	0.635598 (rank : 37)
Query Neighborhood Hits	137	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

ABCBA_MOUSE
θ value	4.74913e-17 (rank : 30)	NC score	0.639136 (rank : 36)
Query Neighborhood Hits	137	Target Neighborhood Hits	97	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JI39, Q542P7, Q9D0C7	Gene names	Abcb10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein).

ABCBB_HUMAN
θ value	2.35696e-16 (rank : 31)	NC score	0.608350 (rank : 46)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	86
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

ABCB5_HUMAN
θ value	6.85773e-16 (rank : 32)	NC score	0.631242 (rank : 38)
Query Neighborhood Hits	137	Target Neighborhood Hits	102	Shared Neighborhood Hits	89
SwissProt Accessions	Q2M3G0, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1	Gene names	ABCB5
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family B member 5 (P-glycoprotein ABCB5) (ABCB5 P-gp).

ABCBB_MOUSE
θ value	6.85773e-16 (rank : 33)	NC score	0.609929 (rank : 45)
Query Neighborhood Hits	137	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

ABCB9_HUMAN
θ value	8.95645e-16 (rank : 34)	NC score	0.588898 (rank : 52)
Query Neighborhood Hits	137	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NP78, Q96AB1, Q9P208	Gene names	ABCB9, KIAA1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9).

ABCG8_HUMAN
θ value	8.95645e-16 (rank : 35)	NC score	0.727184 (rank : 24)
Query Neighborhood Hits	137	Target Neighborhood Hits	92	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H221	Gene names	ABCG8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCG8_MOUSE
θ value	1.52774e-15 (rank : 36)	NC score	0.707735 (rank : 27)
Query Neighborhood Hits	137	Target Neighborhood Hits	89	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBM0	Gene names	Abcg8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCB9_MOUSE
θ value	2.60593e-15 (rank : 37)	NC score	0.587725 (rank : 53)
Query Neighborhood Hits	137	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q9JJ59, Q8CHA1, Q9D212, Q9JIN1	Gene names	Abcb9, Kiaa1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9).

ABCB6_HUMAN
θ value	3.40345e-15 (rank : 38)	NC score	0.642060 (rank : 34)
Query Neighborhood Hits	137	Target Neighborhood Hits	105	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NP58, O75542	Gene names	ABCB6, MTABC3
Domain Architecture
Description	ATP-binding cassette sub-family B member 6, mitochondrial precursor (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (ABC transporter umat).

ABCG1_HUMAN
θ value	4.44505e-15 (rank : 39)	NC score	0.707145 (rank : 28)
Query Neighborhood Hits	137	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	P45844, Q86SU8, Q96L76, Q9BXK6, Q9BXK7, Q9BXK8, Q9BXK9, Q9BXL0, Q9BXL1, Q9BXL2, Q9BXL3, Q9BXL4	Gene names	ABCG1, ABC8, WHT1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG1_MOUSE
θ value	5.8054e-15 (rank : 40)	NC score	0.706558 (rank : 29)
Query Neighborhood Hits	137	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q64343	Gene names	Abcg1, Abc8, Wht1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG4_HUMAN
θ value	5.8054e-15 (rank : 41)	NC score	0.702410 (rank : 30)
Query Neighborhood Hits	137	Target Neighborhood Hits	90	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H172	Gene names	ABCG4, WHITE2
Domain Architecture
Description	ATP-binding cassette sub-family G member 4.

ABCG5_HUMAN
θ value	1.29331e-14 (rank : 42)	NC score	0.720352 (rank : 25)
Query Neighborhood Hits	137	Target Neighborhood Hits	98	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H222	Gene names	ABCG5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCB7_HUMAN
θ value	2.20605e-14 (rank : 43)	NC score	0.654570 (rank : 33)
Query Neighborhood Hits	137	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	O75027, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01	Gene names	ABCB7, ABC7
Domain Architecture
Description	ATP-binding cassette sub-family B member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein).

ABCG2_HUMAN
θ value	1.09485e-13 (rank : 44)	NC score	0.691451 (rank : 31)
Query Neighborhood Hits	137	Target Neighborhood Hits	84	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UNQ0, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64, Q8IX16, Q96LD6, Q96TA8, Q9BY73, Q9NUS0	Gene names	ABCG2, ABCP, BCRP, BCRP1, MXR
Domain Architecture
Description	ATP-binding cassette sub-family G member 2 (Placenta-specific ATP- binding cassette transporter) (Breast cancer resistance protein) (Mitoxantrone resistance-associated protein) (CDw338 antigen).

ABCG2_MOUSE
θ value	1.09485e-13 (rank : 45)	NC score	0.685898 (rank : 32)
Query Neighborhood Hits	137	Target Neighborhood Hits	92	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TMS5, Q9R004, Q9Z1T0	Gene names	Abcg2, Abcp, Bcrp1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein 1 homolog).

ABCG5_MOUSE
θ value	2.69671e-12 (rank : 46)	NC score	0.709314 (rank : 26)
Query Neighborhood Hits	137	Target Neighborhood Hits	95	Shared Neighborhood Hits	83
SwissProt Accessions	Q99PE8	Gene names	Abcg5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

CFTR_HUMAN
θ value	7.84624e-12 (rank : 47)	NC score	0.549939 (rank : 54)
Query Neighborhood Hits	137	Target Neighborhood Hits	104	Shared Neighborhood Hits	86
SwissProt Accessions	P13569	Gene names	CFTR, ABCC7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

TAP2_MOUSE
θ value	1.02475e-11 (rank : 48)	NC score	0.595352 (rank : 51)
Query Neighborhood Hits	137	Target Neighborhood Hits	93	Shared Neighborhood Hits	86
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

ABCB8_HUMAN
θ value	1.33837e-11 (rank : 49)	NC score	0.642056 (rank : 35)
Query Neighborhood Hits	137	Target Neighborhood Hits	91	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NUT2, O95787	Gene names	ABCB8, MABC1
Domain Architecture
Description	ATP-binding cassette sub-family B member 8, mitochondrial precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1).

MRP7_HUMAN
θ value	1.133e-10 (rank : 50)	NC score	0.538621 (rank : 55)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	86
SwissProt Accessions	Q5T3U5, Q8NHX7, Q9H7N2, Q9NXY3, Q9UF48	Gene names	ABCC10, MRP7, SIMRP7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

MRP4_HUMAN
θ value	1.47974e-10 (rank : 51)	NC score	0.514798 (rank : 60)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

TAP2_HUMAN
θ value	1.47974e-10 (rank : 52)	NC score	0.605820 (rank : 49)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	87
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

MRP6_HUMAN
θ value	3.29651e-10 (rank : 53)	NC score	0.506755 (rank : 65)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	86
SwissProt Accessions	O95255, P78420, Q9UMZ7	Gene names	ABCC6, ARA, MRP6
Domain Architecture
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E).

MRP9_HUMAN
θ value	2.13673e-09 (rank : 54)	NC score	0.508096 (rank : 64)
Query Neighborhood Hits	137	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	Q96J65, Q49AL2, Q8TAF0, Q8TEY2	Gene names	ABCC12, MRP9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

ABCC9_MOUSE
θ value	2.79066e-09 (rank : 55)	NC score	0.469800 (rank : 75)
Query Neighborhood Hits	137	Target Neighborhood Hits	110	Shared Neighborhood Hits	87
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

TAP1_HUMAN
θ value	4.76016e-09 (rank : 56)	NC score	0.616366 (rank : 44)
Query Neighborhood Hits	137	Target Neighborhood Hits	99	Shared Neighborhood Hits	86
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

MRP7_MOUSE
θ value	6.21693e-09 (rank : 57)	NC score	0.522491 (rank : 57)
Query Neighborhood Hits	137	Target Neighborhood Hits	99	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R4P9, Q3TCQ0, Q3V0D1, Q8R4S1	Gene names	Abcc10, Mrp7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

ABCC9_HUMAN
θ value	1.06045e-08 (rank : 58)	NC score	0.459192 (rank : 79)
Query Neighborhood Hits	137	Target Neighborhood Hits	108	Shared Neighborhood Hits	87
SwissProt Accessions	O60706, O60707	Gene names	ABCC9, SUR2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

MRP9_MOUSE
θ value	1.06045e-08 (rank : 59)	NC score	0.511851 (rank : 62)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	87
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

TAP1_MOUSE
θ value	1.06045e-08 (rank : 60)	NC score	0.604030 (rank : 50)
Query Neighborhood Hits	137	Target Neighborhood Hits	95	Shared Neighborhood Hits	86
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

CFTR_MOUSE
θ value	1.38499e-08 (rank : 61)	NC score	0.529702 (rank : 56)
Query Neighborhood Hits	137	Target Neighborhood Hits	115	Shared Neighborhood Hits	86
SwissProt Accessions	P26361, Q63893, Q63894, Q9JKQ6	Gene names	Cftr, Abcc7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

MRP1_HUMAN
θ value	4.0297e-08 (rank : 62)	NC score	0.479421 (rank : 72)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	86
SwissProt Accessions	P33527, O14819, O43333, P78419, Q59GI9, Q9UQ97, Q9UQ99, Q9UQA0	Gene names	ABCC1, MRP, MRP1
Domain Architecture
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP5_HUMAN
θ value	4.0297e-08 (rank : 63)	NC score	0.492138 (rank : 69)
Query Neighborhood Hits	137	Target Neighborhood Hits	110	Shared Neighborhood Hits	87
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

MRP5_MOUSE
θ value	4.0297e-08 (rank : 64)	NC score	0.489806 (rank : 70)
Query Neighborhood Hits	137	Target Neighborhood Hits	99	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

MRP2_HUMAN
θ value	5.26297e-08 (rank : 65)	NC score	0.493164 (rank : 68)
Query Neighborhood Hits	137	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q92887, Q14022, Q92500, Q92798, Q99663, Q9UMS2	Gene names	ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein).

MRP6_MOUSE
θ value	5.26297e-08 (rank : 66)	NC score	0.494076 (rank : 67)
Query Neighborhood Hits	137	Target Neighborhood Hits	105	Shared Neighborhood Hits	86
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

ABCF2_HUMAN
θ value	3.41135e-07 (rank : 67)	NC score	0.513765 (rank : 61)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UG63, O60864, Q96TE8	Gene names	ABCF2
Domain Architecture
Description	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2).

ABCF2_MOUSE
θ value	3.41135e-07 (rank : 68)	NC score	0.515853 (rank : 58)
Query Neighborhood Hits	137	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

MRP2_MOUSE
θ value	4.45536e-07 (rank : 69)	NC score	0.473518 (rank : 73)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

ABCCB_HUMAN
θ value	9.92553e-07 (rank : 70)	NC score	0.494761 (rank : 66)
Query Neighborhood Hits	137	Target Neighborhood Hits	118	Shared Neighborhood Hits	87
SwissProt Accessions	Q96J66, Q8TDJ0, Q96JA6, Q9BX80	Gene names	ABCC11, MRP8
Domain Architecture	No domain graphic available
Description	ATP-binding cassette transporter sub-family C member 11 (Multidrug resistance-associated protein 8).

MRP3_HUMAN
θ value	9.92553e-07 (rank : 71)	NC score	0.467724 (rank : 76)
Query Neighborhood Hits	137	Target Neighborhood Hits	125	Shared Neighborhood Hits	87
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

ABCG3_MOUSE
θ value	3.77169e-06 (rank : 72)	NC score	0.515253 (rank : 59)
Query Neighborhood Hits	137	Target Neighborhood Hits	67	Shared Neighborhood Hits	58
SwissProt Accessions	Q99P81	Gene names	Abcg3
Domain Architecture
Description	ATP-binding cassette sub-family G member 3.

ABCE1_HUMAN
θ value	4.92598e-06 (rank : 73)	NC score	0.607642 (rank : 47)
Query Neighborhood Hits	137	Target Neighborhood Hits	114	Shared Neighborhood Hits	88
SwissProt Accessions	P61221, O88793, Q13181, Q13864, Q6NR76, Q96AL0, Q96B10, Q99K66	Gene names	ABCE1, RLI
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5' oligoadenylate-binding protein) (HuHP68).

ABCE1_MOUSE
θ value	4.92598e-06 (rank : 74)	NC score	0.607642 (rank : 48)
Query Neighborhood Hits	137	Target Neighborhood Hits	114	Shared Neighborhood Hits	88
SwissProt Accessions	P61222, O88793, Q13181, Q13864, Q96AL0, Q96B10, Q99K66	Gene names	Abce1, Rli
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I).

MRP1_MOUSE
θ value	1.09739e-05 (rank : 75)	NC score	0.471588 (rank : 74)
Query Neighborhood Hits	137	Target Neighborhood Hits	110	Shared Neighborhood Hits	86
SwissProt Accessions	O35379	Gene names	Abcc1, Abcc1a, Abcc1b, Mdrap, Mrp
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

ABCF3_MOUSE
θ value	1.87187e-05 (rank : 76)	NC score	0.509893 (rank : 63)
Query Neighborhood Hits	137	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCF3_HUMAN
θ value	7.1131e-05 (rank : 77)	NC score	0.489032 (rank : 71)
Query Neighborhood Hits	137	Target Neighborhood Hits	117	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NUQ8, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8	Gene names	ABCF3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

ABCC8_HUMAN
θ value	0.00020696 (rank : 78)	NC score	0.434946 (rank : 80)
Query Neighborhood Hits	137	Target Neighborhood Hits	118	Shared Neighborhood Hits	87
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

ABCF1_MOUSE
θ value	0.000786445 (rank : 79)	NC score	0.466779 (rank : 77)
Query Neighborhood Hits	137	Target Neighborhood Hits	321	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ABCF1_HUMAN
θ value	0.00134147 (rank : 80)	NC score	0.461410 (rank : 78)
Query Neighborhood Hits	137	Target Neighborhood Hits	343	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

ABCD4_HUMAN
θ value	0.0330416 (rank : 81)	NC score	0.419708 (rank : 81)
Query Neighborhood Hits	137	Target Neighborhood Hits	95	Shared Neighborhood Hits	83
SwissProt Accessions	O14678	Gene names	ABCD4, PXMP1L
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCD4_MOUSE
θ value	0.21417 (rank : 82)	NC score	0.372595 (rank : 82)
Query Neighborhood Hits	137	Target Neighborhood Hits	94	Shared Neighborhood Hits	80
SwissProt Accessions	O89016	Gene names	Abcd4, Pxmp1l
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

GBRP_HUMAN
θ value	0.47712 (rank : 83)	NC score	0.009461 (rank : 100)
Query Neighborhood Hits	137	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	O00591	Gene names	GABRP
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit pi precursor (GABA(A) receptor subunit pi).

GBRP_MOUSE
θ value	0.47712 (rank : 84)	NC score	0.009412 (rank : 101)
Query Neighborhood Hits	137	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q8QZW7, Q3TUT6	Gene names	Gabrp
Domain Architecture	No domain graphic available
Description	Gamma-aminobutyric-acid receptor subunit pi precursor (GABA(A) receptor subunit pi).

S4A7_HUMAN
θ value	0.47712 (rank : 85)	NC score	0.007511 (rank : 105)
Query Neighborhood Hits	137	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6M7, O60350, Q6AHZ9, Q9HC88, Q9UIB9	Gene names	SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7).

ABCD3_MOUSE
θ value	0.62314 (rank : 86)	NC score	0.264616 (rank : 85)
Query Neighborhood Hits	137	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	P55096	Gene names	Abcd3, Pmp70, Pxmp1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70) (PMP68).

ABCD2_HUMAN
θ value	0.813845 (rank : 87)	NC score	0.249543 (rank : 86)
Query Neighborhood Hits	137	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UBJ2, Q13210	Gene names	ABCD2, ALD1, ALDL1, ALDR, ALDRP
Domain Architecture
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein) (hALDR) (Adrenoleukodystrophy-like 1).

ABCD2_MOUSE
θ value	0.813845 (rank : 88)	NC score	0.247437 (rank : 87)
Query Neighborhood Hits	137	Target Neighborhood Hits	88	Shared Neighborhood Hits	75
SwissProt Accessions	Q61285, Q8BQ63, Q8C4B6	Gene names	Abcd2, Aldr
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein).

O52E8_HUMAN
θ value	0.813845 (rank : 89)	NC score	-0.004040 (rank : 138)
Query Neighborhood Hits	137	Target Neighborhood Hits	696	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IFG1	Gene names	OR52E8
Domain Architecture	No domain graphic available
Description	Olfactory receptor 52E8 (Olfactory receptor OR11-54).

PLCB4_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.008309 (rank : 103)
Query Neighborhood Hits	137	Target Neighborhood Hits	658	Shared Neighborhood Hits	8
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

ABCD3_HUMAN
θ value	1.06291 (rank : 91)	NC score	0.273727 (rank : 83)
Query Neighborhood Hits	137	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	P28288, Q15271, Q9H529	Gene names	ABCD3, PMP70, PXMP1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70).

RB6I2_HUMAN
θ value	1.06291 (rank : 92)	NC score	-0.000238 (rank : 131)
Query Neighborhood Hits	137	Target Neighborhood Hits	1584	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RAD50_HUMAN
θ value	1.38821 (rank : 93)	NC score	0.031845 (rank : 92)
Query Neighborhood Hits	137	Target Neighborhood Hits	1317	Shared Neighborhood Hits	41
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	1.38821 (rank : 94)	NC score	0.032655 (rank : 91)
Query Neighborhood Hits	137	Target Neighborhood Hits	1366	Shared Neighborhood Hits	43
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

SNX23_HUMAN
θ value	1.38821 (rank : 95)	NC score	0.002885 (rank : 122)
Query Neighborhood Hits	137	Target Neighborhood Hits	944	Shared Neighborhood Hits	10
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

CTL2_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.012392 (rank : 97)
Query Neighborhood Hits	137	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWA5, Q658V1, Q658Z2, Q6PJV7, Q8N2F0, Q9NY68	Gene names	SLC44A2, CTL2
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 2 (Solute carrier family 44 member 2).

EI24_MOUSE
θ value	1.81305 (rank : 97)	NC score	0.025902 (rank : 93)
Query Neighborhood Hits	137	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q61070	Gene names	Ei24, Pig8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

CF154_HUMAN
θ value	2.36792 (rank : 98)	NC score	0.013471 (rank : 96)
Query Neighborhood Hits	137	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

CKAP5_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.020378 (rank : 94)
Query Neighborhood Hits	137	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

OR4C6_HUMAN
θ value	2.36792 (rank : 100)	NC score	-0.005153 (rank : 139)
Query Neighborhood Hits	137	Target Neighborhood Hits	801	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NH72, Q6IFD2	Gene names	OR4C6
Domain Architecture
Description	Olfactory receptor 4C6 (Olfactory receptor OR11-138).

PPM1F_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.008370 (rank : 102)
Query Neighborhood Hits	137	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P49593, Q96PM2	Gene names	PPM1F, KIAA0015, POPX2
Domain Architecture
Description	Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (hFEM-2) (Protein phosphatase 1F).

CTL2_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.011292 (rank : 98)
Query Neighborhood Hits	137	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY89, Q8K2F1	Gene names	Slc44a2, Ctl2
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 2 (Solute carrier family 44 member 2).

F13A_HUMAN
θ value	3.0926 (rank : 103)	NC score	0.005279 (rank : 111)
Query Neighborhood Hits	137	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P00488, Q8N6X2, Q96P24	Gene names	F13A1, F13A
Domain Architecture
Description	Coagulation factor XIII A chain precursor (EC 2.3.2.13) (Coagulation factor XIIIa) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain).

T2R43_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.001972 (rank : 125)
Query Neighborhood Hits	137	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	P59537, P59546	Gene names	TAS2R43
Domain Architecture
Description	Taste receptor type 2 member 43 (T2R43) (T2R52).

CEND3_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.003257 (rank : 119)
Query Neighborhood Hits	137	Target Neighborhood Hits	275	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CXCR6_HUMAN
θ value	4.03905 (rank : 106)	NC score	-0.003115 (rank : 135)
Query Neighborhood Hits	137	Target Neighborhood Hits	553	Shared Neighborhood Hits	5
SwissProt Accessions	O00574, O00575, Q9HCA5	Gene names	CXCR6, BONZO, STRL33, TYMSTR
Domain Architecture
Description	C-X-C chemokine receptor type 6 (CXC-R6) (CXCR-6) (G-protein coupled receptor bonzo) (G-protein coupled receptor STRL33) (CDw186 antigen).

KIF4A_HUMAN
θ value	4.03905 (rank : 107)	NC score	-0.000647 (rank : 133)
Query Neighborhood Hits	137	Target Neighborhood Hits	1159	Shared Neighborhood Hits	10
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

NTR1_HUMAN
θ value	4.03905 (rank : 108)	NC score	-0.003117 (rank : 136)
Query Neighborhood Hits	137	Target Neighborhood Hits	826	Shared Neighborhood Hits	6
SwissProt Accessions	P30989, Q9H4H1, Q9H4T5	Gene names	NTSR1, NTRR
Domain Architecture
Description	Neurotensin receptor type 1 (NT-R-1) (High-affinity levocabastine- insensitive neurotensin receptor) (NTRH).

SPA3N_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.000037 (rank : 130)
Query Neighborhood Hits	137	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WP6, Q62258	Gene names	Serpina3n, Spi2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3N precursor (Serpin A3N).

TRPA1_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.009711 (rank : 99)
Query Neighborhood Hits	137	Target Neighborhood Hits	343	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TYRP2_MOUSE
θ value	4.03905 (rank : 111)	NC score	0.008219 (rank : 104)
Query Neighborhood Hits	137	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P29812	Gene names	Dct, Tyrp-2, Tyrp2
Domain Architecture
Description	L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2) (SLATY locus protein).

CEND3_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.003103 (rank : 121)
Query Neighborhood Hits	137	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

EI24_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.019372 (rank : 95)
Query Neighborhood Hits	137	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O14681	Gene names	EI24, PIG8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

KIF5A_HUMAN
θ value	5.27518 (rank : 114)	NC score	-0.000506 (rank : 132)
Query Neighborhood Hits	137	Target Neighborhood Hits	843	Shared Neighborhood Hits	9
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

RPGR_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.004776 (rank : 114)
Query Neighborhood Hits	137	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

UCP1_MOUSE
θ value	5.27518 (rank : 116)	NC score	0.005076 (rank : 113)
Query Neighborhood Hits	137	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	P12242	Gene names	Ucp1, Ucp
Domain Architecture
Description	Mitochondrial brown fat uncoupling protein 1 (UCP 1) (Thermogenin).

ADAM8_MOUSE
θ value	6.88961 (rank : 117)	NC score	-0.001069 (rank : 134)
Query Neighborhood Hits	137	Target Neighborhood Hits	326	Shared Neighborhood Hits	2
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CTHR1_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.004657 (rank : 115)
Query Neighborhood Hits	137	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.004656 (rank : 116)
Query Neighborhood Hits	137	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

DDX56_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.000199 (rank : 129)
Query Neighborhood Hits	137	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

LRRK2_HUMAN
θ value	6.88961 (rank : 121)	NC score	-0.007357 (rank : 140)
Query Neighborhood Hits	137	Target Neighborhood Hits	1382	Shared Neighborhood Hits	6
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

OLFL1_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.006793 (rank : 110)
Query Neighborhood Hits	137	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWY5	Gene names	OLFML1
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 1 precursor.

PANX3_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.005193 (rank : 112)
Query Neighborhood Hits	137	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CEG0, Q8CB28	Gene names	Panx3
Domain Architecture	No domain graphic available
Description	Pannexin-3.

ABCD1_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.243331 (rank : 88)
Query Neighborhood Hits	137	Target Neighborhood Hits	92	Shared Neighborhood Hits	77
SwissProt Accessions	P48410, Q9QY41, Q9QZ32	Gene names	Abcd1, Ald, Aldgh
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

AP2A_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.007152 (rank : 109)
Query Neighborhood Hits	137	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P05549, Q13777	Gene names	TFAP2A, AP2TF, TFAP2
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).

AP2A_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.007161 (rank : 108)
Query Neighborhood Hits	137	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P34056, Q60740, Q60741, Q60742, Q60743, Q62067, Q62068, Q62069, Q91VX0, Q9CRY4	Gene names	Tfap2a, Ap2tf, Tcfap2a
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (Activator protein 2) (AP-2).

AP2B_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.007294 (rank : 107)
Query Neighborhood Hits	137	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.007295 (rank : 106)
Query Neighborhood Hits	137	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

CASP3_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.002054 (rank : 124)
Query Neighborhood Hits	137	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P42574, Q96AN1, Q96KP2	Gene names	CASP3, CPP32
Domain Architecture
Description	Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit].

CCNE1_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.002332 (rank : 123)
Query Neighborhood Hits	137	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P24864, Q14091, Q8NFG1, Q92501	Gene names	CCNE1, CCNE
Domain Architecture
Description	G1/S-specific cyclin-E1.

F13A_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.004613 (rank : 117)
Query Neighborhood Hits	137	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH61, Q3TNF9, Q8BIP2	Gene names	F13a1, F13a
Domain Architecture	No domain graphic available
Description	Coagulation factor XIII A chain precursor (EC 2.3.2.13) (Coagulation factor XIIIa) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain).

GP141_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.001042 (rank : 128)
Query Neighborhood Hits	137	Target Neighborhood Hits	301	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z602, Q86SP3	Gene names	GPR141, PGR13
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13).

NTR1_MOUSE
θ value	8.99809 (rank : 133)	NC score	-0.003784 (rank : 137)
Query Neighborhood Hits	137	Target Neighborhood Hits	821	Shared Neighborhood Hits	6
SwissProt Accessions	O88319	Gene names	Ntsr1, Ntsr
Domain Architecture
Description	Neurotensin receptor type 1 (NT-R-1).

SENP1_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.003224 (rank : 120)
Query Neighborhood Hits	137	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

T2R44_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.001146 (rank : 127)
Query Neighborhood Hits	137	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	P59538, P59547, Q645X5	Gene names	TAS2R44
Domain Architecture
Description	Taste receptor type 2 member 44 (T2R44) (T2R53).

TCAL4_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.003595 (rank : 118)
Query Neighborhood Hits	137	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EI5, Q8WY12, Q9H2H1, Q9H775	Gene names	TCEAL4
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 4 (TCEA-like protein 4) (Transcription elongation factor S-II protein-like 4).

TRPM7_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.001581 (rank : 126)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

ABCCD_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.153771 (rank : 89)
Query Neighborhood Hits	137	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NSE7, Q8N6A4, Q8N6A5	Gene names	ABCC13, C21orf73, PRED6
Domain Architecture
Description	Putative ATP-binding cassette transporter C13.

ABCD1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.268215 (rank : 84)
Query Neighborhood Hits	137	Target Neighborhood Hits	91	Shared Neighborhood Hits	77
SwissProt Accessions	P33897, Q6GTZ2	Gene names	ABCD1, ALD
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

MDN1_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.077545 (rank : 90)
Query Neighborhood Hits	137	Target Neighborhood Hits	662	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

Hits sorted by NC score

ABCA5_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	137	Target Neighborhood Hits	137	Shared Neighborhood Hits	137
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA5_HUMAN
NC score	0.998319 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	137	Target Neighborhood Hits	146	Shared Neighborhood Hits	103
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

ABCA6_HUMAN
NC score	0.988369 (rank : 3)	θ value	0 (rank : 5)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N139, Q6NSH9, Q8N856, Q8WWZ6	Gene names	ABCA6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCA9_MOUSE
NC score	0.988033 (rank : 4)	θ value	0 (rank : 9)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCA6_MOUSE
NC score	0.987943 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	137	Target Neighborhood Hits	111	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K441, Q8BGH0, Q8BPT1	Gene names	Abca6
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 6.

ABCAA_HUMAN
NC score	0.987237 (rank : 6)	θ value	0 (rank : 10)
Query Neighborhood Hits	137	Target Neighborhood Hits	123	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WWZ4, Q6PIQ6, Q7Z2I9, Q7Z7P7, Q86TD2	Gene names	ABCA10
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 10.

ABC8B_MOUSE
NC score	0.987129 (rank : 7)	θ value	0 (rank : 2)
Query Neighborhood Hits	137	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	Q8K440, Q69ZY4, Q8BRQ1, Q9JL38	Gene names	Abca8b, Abca8, Kiaa0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-B.

ABC8A_MOUSE
NC score	0.987108 (rank : 8)	θ value	0 (rank : 1)
Query Neighborhood Hits	137	Target Neighborhood Hits	115	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K442, Q6PAV3, Q8C0A9, Q8R0R4	Gene names	Abca8a
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8-A.

ABCA9_HUMAN
NC score	0.986745 (rank : 9)	θ value	0 (rank : 8)
Query Neighborhood Hits	137	Target Neighborhood Hits	111	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCA8_HUMAN
NC score	0.981485 (rank : 10)	θ value	0 (rank : 7)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	88
SwissProt Accessions	O94911, Q86WW0	Gene names	ABCA8, KIAA0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8.

ABCA3_MOUSE
NC score	0.929913 (rank : 11)	θ value	2.54619e-95 (rank : 11)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R420	Gene names	Abca3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3.

ABCA3_HUMAN
NC score	0.922855 (rank : 12)	θ value	2.46618e-90 (rank : 12)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	89
SwissProt Accessions	Q99758, Q54A95, Q92473	Gene names	ABCA3, ABC3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3 (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (ABC-C transporter).

ABCA2_HUMAN
NC score	0.893539 (rank : 13)	θ value	6.30065e-78 (rank : 14)
Query Neighborhood Hits	137	Target Neighborhood Hits	143	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCA2_MOUSE
NC score	0.889057 (rank : 14)	θ value	3.45727e-76 (rank : 16)
Query Neighborhood Hits	137	Target Neighborhood Hits	124	Shared Neighborhood Hits	85
SwissProt Accessions	P41234	Gene names	Abca2, Abc2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

ABCAC_HUMAN
NC score	0.887514 (rank : 15)	θ value	2.64714e-76 (rank : 15)
Query Neighborhood Hits	137	Target Neighborhood Hits	123	Shared Neighborhood Hits	89
SwissProt Accessions	Q86UK0, Q8IZW6, Q96JT3, Q9Y4M5	Gene names	ABCA12, ABC12
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 12 (ATP-binding cassette transporter 12) (ATP-binding cassette 12).

ABCA1_MOUSE
NC score	0.875958 (rank : 16)	θ value	1.49966e-79 (rank : 13)
Query Neighborhood Hits	137	Target Neighborhood Hits	112	Shared Neighborhood Hits	88
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

ABCA7_HUMAN
NC score	0.874173 (rank : 17)	θ value	7.98882e-65 (rank : 21)
Query Neighborhood Hits	137	Target Neighborhood Hits	144	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IZY2, Q96S58, Q9BZC4, Q9NR73, Q9UKP8	Gene names	ABCA7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7 (Macrophage ABC transporter) (Autoantigen SS-N) (ABCA-SSN).

ABCA1_HUMAN
NC score	0.873244 (rank : 18)	θ value	1.60597e-73 (rank : 18)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	88
SwissProt Accessions	O95477, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08, Q9UN09	Gene names	ABCA1, ABC1, CERP
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1) (Cholesterol efflux regulatory protein).

ABCA7_MOUSE
NC score	0.872163 (rank : 19)	θ value	5.17823e-64 (rank : 23)
Query Neighborhood Hits	137	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q91V24, Q9JL36	Gene names	Abca7
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 7.

ABCAD_MOUSE
NC score	0.871854 (rank : 20)	θ value	1.89707e-74 (rank : 17)
Query Neighborhood Hits	137	Target Neighborhood Hits	150	Shared Neighborhood Hits	86
SwissProt Accessions	Q5SSE9, Q80T20, Q8BHZ2, Q8CB91	Gene names	Abca13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCAD_HUMAN
NC score	0.871774 (rank : 21)	θ value	5.71191e-71 (rank : 19)
Query Neighborhood Hits	137	Target Neighborhood Hits	207	Shared Neighborhood Hits	86
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ABCA4_HUMAN
NC score	0.870103 (rank : 22)	θ value	3.96481e-64 (rank : 22)
Query Neighborhood Hits	137	Target Neighborhood Hits	116	Shared Neighborhood Hits	89
SwissProt Accessions	P78363, O15112, O60438, O60915	Gene names	ABCA4, ABCR
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein).

ABCA4_MOUSE
NC score	0.869061 (rank : 23)	θ value	2.4834e-66 (rank : 20)
Query Neighborhood Hits	137	Target Neighborhood Hits	126	Shared Neighborhood Hits	89
SwissProt Accessions	O35600	Gene names	Abca4, Abcr
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP).

ABCG8_HUMAN
NC score	0.727184 (rank : 24)	θ value	8.95645e-16 (rank : 35)
Query Neighborhood Hits	137	Target Neighborhood Hits	92	Shared Neighborhood Hits	87
SwissProt Accessions	Q9H221	Gene names	ABCG8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCG5_HUMAN
NC score	0.720352 (rank : 25)	θ value	1.29331e-14 (rank : 42)
Query Neighborhood Hits	137	Target Neighborhood Hits	98	Shared Neighborhood Hits	86
SwissProt Accessions	Q9H222	Gene names	ABCG5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCG5_MOUSE
NC score	0.709314 (rank : 26)	θ value	2.69671e-12 (rank : 46)
Query Neighborhood Hits	137	Target Neighborhood Hits	95	Shared Neighborhood Hits	83
SwissProt Accessions	Q99PE8	Gene names	Abcg5
Domain Architecture
Description	ATP-binding cassette sub-family G member 5 (Sterolin-1).

ABCG8_MOUSE
NC score	0.707735 (rank : 27)	θ value	1.52774e-15 (rank : 36)
Query Neighborhood Hits	137	Target Neighborhood Hits	89	Shared Neighborhood Hits	86
SwissProt Accessions	Q9DBM0	Gene names	Abcg8
Domain Architecture
Description	ATP-binding cassette sub-family G member 8 (Sterolin-2).

ABCG1_HUMAN
NC score	0.707145 (rank : 28)	θ value	4.44505e-15 (rank : 39)
Query Neighborhood Hits	137	Target Neighborhood Hits	97	Shared Neighborhood Hits	86
SwissProt Accessions	P45844, Q86SU8, Q96L76, Q9BXK6, Q9BXK7, Q9BXK8, Q9BXK9, Q9BXL0, Q9BXL1, Q9BXL2, Q9BXL3, Q9BXL4	Gene names	ABCG1, ABC8, WHT1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG1_MOUSE
NC score	0.706558 (rank : 29)	θ value	5.8054e-15 (rank : 40)
Query Neighborhood Hits	137	Target Neighborhood Hits	100	Shared Neighborhood Hits	86
SwissProt Accessions	Q64343	Gene names	Abcg1, Abc8, Wht1
Domain Architecture
Description	ATP-binding cassette sub-family G member 1 (White protein homolog) (ATP-binding cassette transporter 8).

ABCG4_HUMAN
NC score	0.702410 (rank : 30)	θ value	5.8054e-15 (rank : 41)
Query Neighborhood Hits	137	Target Neighborhood Hits	90	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H172	Gene names	ABCG4, WHITE2
Domain Architecture
Description	ATP-binding cassette sub-family G member 4.

ABCG2_HUMAN
NC score	0.691451 (rank : 31)	θ value	1.09485e-13 (rank : 44)
Query Neighborhood Hits	137	Target Neighborhood Hits	84	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UNQ0, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64, Q8IX16, Q96LD6, Q96TA8, Q9BY73, Q9NUS0	Gene names	ABCG2, ABCP, BCRP, BCRP1, MXR
Domain Architecture
Description	ATP-binding cassette sub-family G member 2 (Placenta-specific ATP- binding cassette transporter) (Breast cancer resistance protein) (Mitoxantrone resistance-associated protein) (CDw338 antigen).

ABCG2_MOUSE
NC score	0.685898 (rank : 32)	θ value	1.09485e-13 (rank : 45)
Query Neighborhood Hits	137	Target Neighborhood Hits	92	Shared Neighborhood Hits	82
SwissProt Accessions	Q7TMS5, Q9R004, Q9Z1T0	Gene names	Abcg2, Abcp, Bcrp1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family G member 2 (Breast cancer resistance protein 1 homolog).

ABCB7_HUMAN
NC score	0.654570 (rank : 33)	θ value	2.20605e-14 (rank : 43)
Query Neighborhood Hits	137	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	O75027, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01	Gene names	ABCB7, ABC7
Domain Architecture
Description	ATP-binding cassette sub-family B member 7, mitochondrial precursor (ATP-binding cassette transporter 7) (ABC transporter 7 protein).

ABCB6_HUMAN
NC score	0.642060 (rank : 34)	θ value	3.40345e-15 (rank : 38)
Query Neighborhood Hits	137	Target Neighborhood Hits	105	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NP58, O75542	Gene names	ABCB6, MTABC3
Domain Architecture
Description	ATP-binding cassette sub-family B member 6, mitochondrial precursor (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (ABC transporter umat).

ABCB8_HUMAN
NC score	0.642056 (rank : 35)	θ value	1.33837e-11 (rank : 49)
Query Neighborhood Hits	137	Target Neighborhood Hits	91	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NUT2, O95787	Gene names	ABCB8, MABC1
Domain Architecture
Description	ATP-binding cassette sub-family B member 8, mitochondrial precursor (Mitochondrial ATP-binding cassette 1) (M-ABC1).

ABCBA_MOUSE
NC score	0.639136 (rank : 36)	θ value	4.74913e-17 (rank : 30)
Query Neighborhood Hits	137	Target Neighborhood Hits	97	Shared Neighborhood Hits	88
SwissProt Accessions	Q9JI39, Q542P7, Q9D0C7	Gene names	Abcb10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (ABC-mitochondrial erythroid protein) (ABC-me protein).

ABCBA_HUMAN
NC score	0.635598 (rank : 37)	θ value	5.60996e-18 (rank : 29)
Query Neighborhood Hits	137	Target Neighborhood Hits	102	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NRK6, Q13040, Q9H3V0	Gene names	ABCB10
Domain Architecture
Description	ATP-binding cassette sub-family B member 10, mitochondrial precursor (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2).

ABCB5_HUMAN
NC score	0.631242 (rank : 38)	θ value	6.85773e-16 (rank : 32)
Query Neighborhood Hits	137	Target Neighborhood Hits	102	Shared Neighborhood Hits	89
SwissProt Accessions	Q2M3G0, Q2M3I5, Q5I5Q7, Q5I5Q8, Q6KG50, Q6XFQ5, Q8IXA1	Gene names	ABCB5
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family B member 5 (P-glycoprotein ABCB5) (ABCB5 P-gp).

MDR2_MOUSE
NC score	0.629549 (rank : 39)	θ value	6.62687e-19 (rank : 26)
Query Neighborhood Hits	137	Target Neighborhood Hits	108	Shared Neighborhood Hits	89
SwissProt Accessions	P21440, Q6LCL9	Gene names	Abcb4, Mdr2, Pgy-2, Pgy2
Domain Architecture
Description	Multidrug resistance protein 2 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 2).

MDR1_MOUSE
NC score	0.626069 (rank : 40)	θ value	1.47631e-18 (rank : 27)
Query Neighborhood Hits	137	Target Neighborhood Hits	105	Shared Neighborhood Hits	87
SwissProt Accessions	P06795	Gene names	Abcb1, Abcb1b, Mdr1, Mdr1b, Pgy1, Pgy1-1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_MOUSE
NC score	0.625794 (rank : 41)	θ value	2.27762e-19 (rank : 25)
Query Neighborhood Hits	137	Target Neighborhood Hits	106	Shared Neighborhood Hits	87
SwissProt Accessions	P21447	Gene names	Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (P-glycoprotein 3) (MDR1A).

MDR1_HUMAN
NC score	0.623823 (rank : 42)	θ value	2.27762e-19 (rank : 24)
Query Neighborhood Hits	137	Target Neighborhood Hits	112	Shared Neighborhood Hits	89
SwissProt Accessions	P08183, Q12755, Q14812	Gene names	ABCB1, MDR1, PGY1
Domain Architecture
Description	Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD243 antigen).

MDR3_HUMAN
NC score	0.622919 (rank : 43)	θ value	4.29542e-18 (rank : 28)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	89
SwissProt Accessions	P21439, Q14813	Gene names	ABCB4, MDR3, PGY3
Domain Architecture
Description	Multidrug resistance protein 3 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 4) (P-glycoprotein 3).

TAP1_HUMAN
NC score	0.616366 (rank : 44)	θ value	4.76016e-09 (rank : 56)
Query Neighborhood Hits	137	Target Neighborhood Hits	99	Shared Neighborhood Hits	86
SwissProt Accessions	Q03518, Q16149	Gene names	TAP1, ABCB2, PSF1, RING4, Y3
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Peptide transporter PSF1) (Peptide supply factor 1) (PSF-1) (Peptide transporter involved in antigen processing 1).

ABCBB_MOUSE
NC score	0.609929 (rank : 45)	θ value	6.85773e-16 (rank : 33)
Query Neighborhood Hits	137	Target Neighborhood Hits	97	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QY30, Q9QZE8	Gene names	Abcb11, Bsep, Spgp
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein).

ABCBB_HUMAN
NC score	0.608350 (rank : 46)	θ value	2.35696e-16 (rank : 31)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	86
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

ABCE1_HUMAN
NC score	0.607642 (rank : 47)	θ value	4.92598e-06 (rank : 73)
Query Neighborhood Hits	137	Target Neighborhood Hits	114	Shared Neighborhood Hits	88
SwissProt Accessions	P61221, O88793, Q13181, Q13864, Q6NR76, Q96AL0, Q96B10, Q99K66	Gene names	ABCE1, RLI
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) (2'-5' oligoadenylate-binding protein) (HuHP68).

ABCE1_MOUSE
NC score	0.607642 (rank : 48)	θ value	4.92598e-06 (rank : 74)
Query Neighborhood Hits	137	Target Neighborhood Hits	114	Shared Neighborhood Hits	88
SwissProt Accessions	P61222, O88793, Q13181, Q13864, Q96AL0, Q96B10, Q99K66	Gene names	Abce1, Rli
Domain Architecture
Description	ATP-binding cassette sub-family E member 1 (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I).

TAP2_HUMAN
NC score	0.605820 (rank : 49)	θ value	1.47974e-10 (rank : 52)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	87
SwissProt Accessions	Q03519, Q9UQ83	Gene names	TAP2, ABCB3, PSF2, RING11, Y1
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Peptide transporter TAP2) (Peptide transporter PSF2) (Peptide supply factor 2) (PSF-2) (Peptide transporter involved in antigen processing 2).

TAP1_MOUSE
NC score	0.604030 (rank : 50)	θ value	1.06045e-08 (rank : 60)
Query Neighborhood Hits	137	Target Neighborhood Hits	95	Shared Neighborhood Hits	86
SwissProt Accessions	P21958	Gene names	Tap1, Abcb2, Ham-1, Ham1
Domain Architecture
Description	Antigen peptide transporter 1 (APT1) (Peptide transporter TAP1) (ATP- binding cassette sub-family B member 2) (Histocompatibility antigen modifier 1).

TAP2_MOUSE
NC score	0.595352 (rank : 51)	θ value	1.02475e-11 (rank : 48)
Query Neighborhood Hits	137	Target Neighborhood Hits	93	Shared Neighborhood Hits	86
SwissProt Accessions	P36371	Gene names	Tap2, Abcb3, Ham-2, Ham2
Domain Architecture
Description	Antigen peptide transporter 2 (APT2) (ATP-binding cassette sub-family B member 3) (Histocompatibility antigen modifier 2).

ABCB9_HUMAN
NC score	0.588898 (rank : 52)	θ value	8.95645e-16 (rank : 34)
Query Neighborhood Hits	137	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	Q9NP78, Q96AB1, Q9P208	Gene names	ABCB9, KIAA1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (hABCB9).

ABCB9_MOUSE
NC score	0.587725 (rank : 53)	θ value	2.60593e-15 (rank : 37)
Query Neighborhood Hits	137	Target Neighborhood Hits	101	Shared Neighborhood Hits	87
SwissProt Accessions	Q9JJ59, Q8CHA1, Q9D212, Q9JIN1	Gene names	Abcb9, Kiaa1520
Domain Architecture
Description	ATP-binding cassette sub-family B member 9 precursor (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (TAP-like protein) (TAPL) (mABCB9).

CFTR_HUMAN
NC score	0.549939 (rank : 54)	θ value	7.84624e-12 (rank : 47)
Query Neighborhood Hits	137	Target Neighborhood Hits	104	Shared Neighborhood Hits	86
SwissProt Accessions	P13569	Gene names	CFTR, ABCC7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

MRP7_HUMAN
NC score	0.538621 (rank : 55)	θ value	1.133e-10 (rank : 50)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	86
SwissProt Accessions	Q5T3U5, Q8NHX7, Q9H7N2, Q9NXY3, Q9UF48	Gene names	ABCC10, MRP7, SIMRP7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

CFTR_MOUSE
NC score	0.529702 (rank : 56)	θ value	1.38499e-08 (rank : 61)
Query Neighborhood Hits	137	Target Neighborhood Hits	115	Shared Neighborhood Hits	86
SwissProt Accessions	P26361, Q63893, Q63894, Q9JKQ6	Gene names	Cftr, Abcc7
Domain Architecture
Description	Cystic fibrosis transmembrane conductance regulator (CFTR) (cAMP- dependent chloride channel) (ATP-binding cassette transporter sub- family C member 7).

MRP7_MOUSE
NC score	0.522491 (rank : 57)	θ value	6.21693e-09 (rank : 57)
Query Neighborhood Hits	137	Target Neighborhood Hits	99	Shared Neighborhood Hits	86
SwissProt Accessions	Q8R4P9, Q3TCQ0, Q3V0D1, Q8R4S1	Gene names	Abcc10, Mrp7
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 7 (ATP-binding cassette sub- family C member 10).

ABCF2_MOUSE
NC score	0.515853 (rank : 58)	θ value	3.41135e-07 (rank : 68)
Query Neighborhood Hits	137	Target Neighborhood Hits	111	Shared Neighborhood Hits	86
SwissProt Accessions	Q99LE6, Q3UA24, Q8C1S5, Q9JL48	Gene names	Abcf2
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 2.

ABCG3_MOUSE
NC score	0.515253 (rank : 59)	θ value	3.77169e-06 (rank : 72)
Query Neighborhood Hits	137	Target Neighborhood Hits	67	Shared Neighborhood Hits	58
SwissProt Accessions	Q99P81	Gene names	Abcg3
Domain Architecture
Description	ATP-binding cassette sub-family G member 3.

MRP4_HUMAN
NC score	0.514798 (rank : 60)	θ value	1.47974e-10 (rank : 51)
Query Neighborhood Hits	137	Target Neighborhood Hits	107	Shared Neighborhood Hits	87
SwissProt Accessions	O15439, Q9Y6J2	Gene names	ABCC4, MRP4
Domain Architecture
Description	Multidrug resistance-associated protein 4 (ATP-binding cassette sub- family C member 4) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter-B) (MOAT-B).

ABCF2_HUMAN
NC score	0.513765 (rank : 61)	θ value	3.41135e-07 (rank : 67)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UG63, O60864, Q96TE8	Gene names	ABCF2
Domain Architecture
Description	ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2).

MRP9_MOUSE
NC score	0.511851 (rank : 62)	θ value	1.06045e-08 (rank : 59)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	87
SwissProt Accessions	Q80WJ6, Q80WJ2, Q80WJ3, Q8C0P3	Gene names	Abcc12, Mrp9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

ABCF3_MOUSE
NC score	0.509893 (rank : 63)	θ value	1.87187e-05 (rank : 76)
Query Neighborhood Hits	137	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K268, Q9JL49	Gene names	Abcf3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

MRP9_HUMAN
NC score	0.508096 (rank : 64)	θ value	2.13673e-09 (rank : 54)
Query Neighborhood Hits	137	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	Q96J65, Q49AL2, Q8TAF0, Q8TEY2	Gene names	ABCC12, MRP9
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 9 (ATP-binding cassette transporter sub-family C member 12).

MRP6_HUMAN
NC score	0.506755 (rank : 65)	θ value	3.29651e-10 (rank : 53)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	86
SwissProt Accessions	O95255, P78420, Q9UMZ7	Gene names	ABCC6, ARA, MRP6
Domain Architecture
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6) (Anthracycline resistance-associated protein) (Multi-specific organic anion transporter-E) (MOAT-E).

ABCCB_HUMAN
NC score	0.494761 (rank : 66)	θ value	9.92553e-07 (rank : 70)
Query Neighborhood Hits	137	Target Neighborhood Hits	118	Shared Neighborhood Hits	87
SwissProt Accessions	Q96J66, Q8TDJ0, Q96JA6, Q9BX80	Gene names	ABCC11, MRP8
Domain Architecture	No domain graphic available
Description	ATP-binding cassette transporter sub-family C member 11 (Multidrug resistance-associated protein 8).

MRP6_MOUSE
NC score	0.494076 (rank : 67)	θ value	5.26297e-08 (rank : 66)
Query Neighborhood Hits	137	Target Neighborhood Hits	105	Shared Neighborhood Hits	86
SwissProt Accessions	Q9R1S7, Q80YB6	Gene names	Abcc6, Mrp6
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 6 (ATP-binding cassette sub- family C member 6).

MRP2_HUMAN
NC score	0.493164 (rank : 68)	θ value	5.26297e-08 (rank : 65)
Query Neighborhood Hits	137	Target Neighborhood Hits	117	Shared Neighborhood Hits	87
SwissProt Accessions	Q92887, Q14022, Q92500, Q92798, Q99663, Q9UMS2	Gene names	ABCC2, CMOAT, CMOAT1, CMRP, MRP2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein).

MRP5_HUMAN
NC score	0.492138 (rank : 69)	θ value	4.0297e-08 (rank : 63)
Query Neighborhood Hits	137	Target Neighborhood Hits	110	Shared Neighborhood Hits	87
SwissProt Accessions	O15440, O14517, Q9UN85, Q9UNP5, Q9UQC3	Gene names	ABCC5, MRP5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (Multi-specific organic anion transporter-C) (MOAT- C) (pABC11) (SMRP).

MRP5_MOUSE
NC score	0.489806 (rank : 70)	θ value	4.0297e-08 (rank : 64)
Query Neighborhood Hits	137	Target Neighborhood Hits	99	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R1X5, O88284	Gene names	Abcc5, Abcc5a, Mrp5
Domain Architecture
Description	Multidrug resistance-associated protein 5 (ATP-binding cassette sub- family C member 5) (ABC transporter MOAT-C) (SMRP).

ABCF3_HUMAN
NC score	0.489032 (rank : 71)	θ value	7.1131e-05 (rank : 77)
Query Neighborhood Hits	137	Target Neighborhood Hits	117	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NUQ8, Q86UA2, Q8NAN1, Q96GS8, Q9H7A8	Gene names	ABCF3
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 3.

MRP1_HUMAN
NC score	0.479421 (rank : 72)	θ value	4.0297e-08 (rank : 62)
Query Neighborhood Hits	137	Target Neighborhood Hits	103	Shared Neighborhood Hits	86
SwissProt Accessions	P33527, O14819, O43333, P78419, Q59GI9, Q9UQ97, Q9UQ99, Q9UQA0	Gene names	ABCC1, MRP, MRP1
Domain Architecture
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

MRP2_MOUSE
NC score	0.473518 (rank : 73)	θ value	4.45536e-07 (rank : 69)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VI47	Gene names	Abcc2
Domain Architecture
Description	Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2).

MRP1_MOUSE
NC score	0.471588 (rank : 74)	θ value	1.09739e-05 (rank : 75)
Query Neighborhood Hits	137	Target Neighborhood Hits	110	Shared Neighborhood Hits	86
SwissProt Accessions	O35379	Gene names	Abcc1, Abcc1a, Abcc1b, Mdrap, Mrp
Domain Architecture	No domain graphic available
Description	Multidrug resistance-associated protein 1 (ATP-binding cassette sub- family C member 1) (Leukotriene C(4) transporter) (LTC4 transporter).

ABCC9_MOUSE
NC score	0.469800 (rank : 75)	θ value	2.79066e-09 (rank : 55)
Query Neighborhood Hits	137	Target Neighborhood Hits	110	Shared Neighborhood Hits	87
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

MRP3_HUMAN
NC score	0.467724 (rank : 76)	θ value	9.92553e-07 (rank : 71)
Query Neighborhood Hits	137	Target Neighborhood Hits	125	Shared Neighborhood Hits	87
SwissProt Accessions	O15438, O60265, O60922, O75621, O95078, O95289, O95290, Q9UN52	Gene names	ABCC3, CMOAT2, MLP2, MRP3
Domain Architecture
Description	Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3) (Multi-specific organic anion transporter-D) (MOAT-D).

ABCF1_MOUSE
NC score	0.466779 (rank : 77)	θ value	0.000786445 (rank : 79)
Query Neighborhood Hits	137	Target Neighborhood Hits	321	Shared Neighborhood Hits	90
SwissProt Accessions	Q6P542, Q6NV71	Gene names	Abcf1
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1.

ABCF1_HUMAN
NC score	0.461410 (rank : 78)	θ value	0.00134147 (rank : 80)
Query Neighborhood Hits	137	Target Neighborhood Hits	343	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

ABCC9_HUMAN
NC score	0.459192 (rank : 79)	θ value	1.06045e-08 (rank : 58)
Query Neighborhood Hits	137	Target Neighborhood Hits	108	Shared Neighborhood Hits	87
SwissProt Accessions	O60706, O60707	Gene names	ABCC9, SUR2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

ABCC8_HUMAN
NC score	0.434946 (rank : 80)	θ value	0.00020696 (rank : 78)
Query Neighborhood Hits	137	Target Neighborhood Hits	118	Shared Neighborhood Hits	87
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

ABCD4_HUMAN
NC score	0.419708 (rank : 81)	θ value	0.0330416 (rank : 81)
Query Neighborhood Hits	137	Target Neighborhood Hits	95	Shared Neighborhood Hits	83
SwissProt Accessions	O14678	Gene names	ABCD4, PXMP1L
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCD4_MOUSE
NC score	0.372595 (rank : 82)	θ value	0.21417 (rank : 82)
Query Neighborhood Hits	137	Target Neighborhood Hits	94	Shared Neighborhood Hits	80
SwissProt Accessions	O89016	Gene names	Abcd4, Pxmp1l
Domain Architecture
Description	ATP-binding cassette sub-family D member 4 (Peroxisomal membrane protein 69) (PMP69) (Peroxisomal membrane protein 1-like) (PXMP1-L) (P70R).

ABCD3_HUMAN
NC score	0.273727 (rank : 83)	θ value	1.06291 (rank : 91)
Query Neighborhood Hits	137	Target Neighborhood Hits	85	Shared Neighborhood Hits	73
SwissProt Accessions	P28288, Q15271, Q9H529	Gene names	ABCD3, PMP70, PXMP1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70).

ABCD1_HUMAN
NC score	0.268215 (rank : 84)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	137	Target Neighborhood Hits	91	Shared Neighborhood Hits	77
SwissProt Accessions	P33897, Q6GTZ2	Gene names	ABCD1, ALD
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCD3_MOUSE
NC score	0.264616 (rank : 85)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	137	Target Neighborhood Hits	83	Shared Neighborhood Hits	75
SwissProt Accessions	P55096	Gene names	Abcd3, Pmp70, Pxmp1
Domain Architecture
Description	ATP-binding cassette sub-family D member 3 (70 kDa peroxisomal membrane protein) (PMP70) (PMP68).

ABCD2_HUMAN
NC score	0.249543 (rank : 86)	θ value	0.813845 (rank : 87)
Query Neighborhood Hits	137	Target Neighborhood Hits	87	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UBJ2, Q13210	Gene names	ABCD2, ALD1, ALDL1, ALDR, ALDRP
Domain Architecture
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein) (hALDR) (Adrenoleukodystrophy-like 1).

ABCD2_MOUSE
NC score	0.247437 (rank : 87)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	137	Target Neighborhood Hits	88	Shared Neighborhood Hits	75
SwissProt Accessions	Q61285, Q8BQ63, Q8C4B6	Gene names	Abcd2, Aldr
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family D member 2 (Adrenoleukodystrophy- related protein).

ABCD1_MOUSE
NC score	0.243331 (rank : 88)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	137	Target Neighborhood Hits	92	Shared Neighborhood Hits	77
SwissProt Accessions	P48410, Q9QY41, Q9QZ32	Gene names	Abcd1, Ald, Aldgh
Domain Architecture
Description	ATP-binding cassette sub-family D member 1 (Adrenoleukodystrophy protein) (ALDP).

ABCCD_HUMAN
NC score	0.153771 (rank : 89)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	137	Target Neighborhood Hits	24	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NSE7, Q8N6A4, Q8N6A5	Gene names	ABCC13, C21orf73, PRED6
Domain Architecture
Description	Putative ATP-binding cassette transporter C13.

MDN1_HUMAN
NC score	0.077545 (rank : 90)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	137	Target Neighborhood Hits	662	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NU22, O15019	Gene names	MDN1, KIAA0301
Domain Architecture
Description	Midasin (MIDAS-containing protein).

RAD50_MOUSE
NC score	0.032655 (rank : 91)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	137	Target Neighborhood Hits	1366	Shared Neighborhood Hits	43
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RAD50_HUMAN
NC score	0.031845 (rank : 92)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	137	Target Neighborhood Hits	1317	Shared Neighborhood Hits	41
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

EI24_MOUSE
NC score	0.025902 (rank : 93)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	137	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q61070	Gene names	Ei24, Pig8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

CKAP5_HUMAN
NC score	0.020378 (rank : 94)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	137	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

EI24_HUMAN
NC score	0.019372 (rank : 95)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	137	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O14681	Gene names	EI24, PIG8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

CF154_HUMAN
NC score	0.013471 (rank : 96)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	137	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JTD7	Gene names	C6orf154
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf154.

CTL2_HUMAN
NC score	0.012392 (rank : 97)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	137	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWA5, Q658V1, Q658Z2, Q6PJV7, Q8N2F0, Q9NY68	Gene names	SLC44A2, CTL2
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 2 (Solute carrier family 44 member 2).

CTL2_MOUSE
NC score	0.011292 (rank : 98)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	137	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BY89, Q8K2F1	Gene names	Slc44a2, Ctl2
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 2 (Solute carrier family 44 member 2).

TRPA1_MOUSE
NC score	0.009711 (rank : 99)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	137	Target Neighborhood Hits	343	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

GBRP_HUMAN
NC score	0.009461 (rank : 100)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	137	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	O00591	Gene names	GABRP
Domain Architecture
Description	Gamma-aminobutyric-acid receptor subunit pi precursor (GABA(A) receptor subunit pi).

GBRP_MOUSE
NC score	0.009412 (rank : 101)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	137	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q8QZW7, Q3TUT6	Gene names	Gabrp
Domain Architecture	No domain graphic available
Description	Gamma-aminobutyric-acid receptor subunit pi precursor (GABA(A) receptor subunit pi).

PPM1F_HUMAN
NC score	0.008370 (rank : 102)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	137	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P49593, Q96PM2	Gene names	PPM1F, KIAA0015, POPX2
Domain Architecture
Description	Ca(2+)/calmodulin-dependent protein kinase phosphatase (EC 3.1.3.16) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (hFEM-2) (Protein phosphatase 1F).

PLCB4_HUMAN
NC score	0.008309 (rank : 103)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	137	Target Neighborhood Hits	658	Shared Neighborhood Hits	8
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

TYRP2_MOUSE
NC score	0.008219 (rank : 104)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	137	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P29812	Gene names	Dct, Tyrp-2, Tyrp2
Domain Architecture
Description	L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2) (SLATY locus protein).

S4A7_HUMAN
NC score	0.007511 (rank : 105)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	137	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6M7, O60350, Q6AHZ9, Q9HC88, Q9UIB9	Gene names	SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7).

AP2B_MOUSE
NC score	0.007295 (rank : 106)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	137	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_HUMAN
NC score	0.007294 (rank : 107)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	137	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2A_MOUSE
NC score	0.007161 (rank : 108)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	137	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P34056, Q60740, Q60741, Q60742, Q60743, Q62067, Q62068, Q62069, Q91VX0, Q9CRY4	Gene names	Tfap2a, Ap2tf, Tcfap2a
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (Activator protein 2) (AP-2).

AP2A_HUMAN
NC score	0.007152 (rank : 109)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	137	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	P05549, Q13777	Gene names	TFAP2A, AP2TF, TFAP2
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).

OLFL1_HUMAN
NC score	0.006793 (rank : 110)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	137	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWY5	Gene names	OLFML1
Domain Architecture	No domain graphic available
Description	Olfactomedin-like protein 1 precursor.

F13A_HUMAN
NC score	0.005279 (rank : 111)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	137	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P00488, Q8N6X2, Q96P24	Gene names	F13A1, F13A
Domain Architecture
Description	Coagulation factor XIII A chain precursor (EC 2.3.2.13) (Coagulation factor XIIIa) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain).

PANX3_MOUSE
NC score	0.005193 (rank : 112)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	137	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CEG0, Q8CB28	Gene names	Panx3
Domain Architecture	No domain graphic available
Description	Pannexin-3.

UCP1_MOUSE
NC score	0.005076 (rank : 113)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	137	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	P12242	Gene names	Ucp1, Ucp
Domain Architecture
Description	Mitochondrial brown fat uncoupling protein 1 (UCP 1) (Thermogenin).

RPGR_HUMAN
NC score	0.004776 (rank : 114)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	137	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

CTHR1_HUMAN
NC score	0.004657 (rank : 115)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	137	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CG8, Q6UW91, Q8IX63	Gene names	CTHRC1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor (NMTC1 protein).

CTHR1_MOUSE
NC score	0.004656 (rank : 116)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	137	Target Neighborhood Hits	123	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1D6	Gene names	Cthrc1
Domain Architecture	No domain graphic available
Description	Collagen triple helix repeat-containing protein 1 precursor.

F13A_MOUSE
NC score	0.004613 (rank : 117)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	137	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BH61, Q3TNF9, Q8BIP2	Gene names	F13a1, F13a
Domain Architecture	No domain graphic available
Description	Coagulation factor XIII A chain precursor (EC 2.3.2.13) (Coagulation factor XIIIa) (Protein-glutamine gamma-glutamyltransferase A chain) (Transglutaminase A chain).

TCAL4_HUMAN
NC score	0.003595 (rank : 118)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	137	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EI5, Q8WY12, Q9H2H1, Q9H775	Gene names	TCEAL4
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 4 (TCEA-like protein 4) (Transcription elongation factor S-II protein-like 4).

CEND3_HUMAN
NC score	0.003257 (rank : 119)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	137	Target Neighborhood Hits	275	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

SENP1_HUMAN
NC score	0.003224 (rank : 120)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	137	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P0U3, Q86XC8	Gene names	SENP1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

CEND3_MOUSE
NC score	0.003103 (rank : 121)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	137	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

SNX23_HUMAN
NC score	0.002885 (rank : 122)	θ value	1.38821 (rank : 95)
Query Neighborhood Hits	137	Target Neighborhood Hits	944	Shared Neighborhood Hits	10
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

CCNE1_HUMAN
NC score	0.002332 (rank : 123)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	137	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	P24864, Q14091, Q8NFG1, Q92501	Gene names	CCNE1, CCNE
Domain Architecture
Description	G1/S-specific cyclin-E1.

CASP3_HUMAN
NC score	0.002054 (rank : 124)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	137	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P42574, Q96AN1, Q96KP2	Gene names	CASP3, CPP32
Domain Architecture
Description	Caspase-3 precursor (EC 3.4.22.-) (CASP-3) (Apopain) (Cysteine protease CPP32) (Yama protein) (CPP-32) (SREBP cleavage activity 1) (SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit].

T2R43_HUMAN
NC score	0.001972 (rank : 125)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	137	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	P59537, P59546	Gene names	TAS2R43
Domain Architecture
Description	Taste receptor type 2 member 43 (T2R43) (T2R52).

TRPM7_MOUSE
NC score	0.001581 (rank : 126)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	137	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

T2R44_HUMAN
NC score	0.001146 (rank : 127)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	137	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	P59538, P59547, Q645X5	Gene names	TAS2R44
Domain Architecture
Description	Taste receptor type 2 member 44 (T2R44) (T2R53).

GP141_HUMAN
NC score	0.001042 (rank : 128)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	137	Target Neighborhood Hits	301	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z602, Q86SP3	Gene names	GPR141, PGR13
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 141 (G-protein coupled receptor PGR13).

DDX56_HUMAN
NC score	0.000199 (rank : 129)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	137	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NY93, Q9H9I8	Gene names	DDX56, DDX21, NOH61
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX56 (EC 3.6.1.-) (DEAD box protein 56) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD-box protein 21).

SPA3N_MOUSE
NC score	0.000037 (rank : 130)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	137	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q91WP6, Q62258	Gene names	Serpina3n, Spi2
Domain Architecture	No domain graphic available
Description	Serine protease inhibitor A3N precursor (Serpin A3N).

RB6I2_HUMAN
NC score	-0.000238 (rank : 131)	θ value	1.06291 (rank : 92)
Query Neighborhood Hits	137	Target Neighborhood Hits	1584	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

KIF5A_HUMAN
NC score	-0.000506 (rank : 132)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	137	Target Neighborhood Hits	843	Shared Neighborhood Hits	9
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF4A_HUMAN
NC score	-0.000647 (rank : 133)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	137	Target Neighborhood Hits	1159	Shared Neighborhood Hits	10
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

ADAM8_MOUSE
NC score	-0.001069 (rank : 134)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	137	Target Neighborhood Hits	326	Shared Neighborhood Hits	2
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CXCR6_HUMAN
NC score	-0.003115 (rank : 135)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	137	Target Neighborhood Hits	553	Shared Neighborhood Hits	5
SwissProt Accessions	O00574, O00575, Q9HCA5	Gene names	CXCR6, BONZO, STRL33, TYMSTR
Domain Architecture
Description	C-X-C chemokine receptor type 6 (CXC-R6) (CXCR-6) (G-protein coupled receptor bonzo) (G-protein coupled receptor STRL33) (CDw186 antigen).

NTR1_HUMAN
NC score	-0.003117 (rank : 136)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	137	Target Neighborhood Hits	826	Shared Neighborhood Hits	6
SwissProt Accessions	P30989, Q9H4H1, Q9H4T5	Gene names	NTSR1, NTRR
Domain Architecture
Description	Neurotensin receptor type 1 (NT-R-1) (High-affinity levocabastine- insensitive neurotensin receptor) (NTRH).

NTR1_MOUSE
NC score	-0.003784 (rank : 137)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	137	Target Neighborhood Hits	821	Shared Neighborhood Hits	6
SwissProt Accessions	O88319	Gene names	Ntsr1, Ntsr
Domain Architecture
Description	Neurotensin receptor type 1 (NT-R-1).

O52E8_HUMAN
NC score	-0.004040 (rank : 138)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	137	Target Neighborhood Hits	696	Shared Neighborhood Hits	5
SwissProt Accessions	Q6IFG1	Gene names	OR52E8
Domain Architecture	No domain graphic available
Description	Olfactory receptor 52E8 (Olfactory receptor OR11-54).

OR4C6_HUMAN
NC score	-0.005153 (rank : 139)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	137	Target Neighborhood Hits	801	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NH72, Q6IFD2	Gene names	OR4C6
Domain Architecture
Description	Olfactory receptor 4C6 (Olfactory receptor OR11-138).

LRRK2_HUMAN
NC score	-0.007357 (rank : 140)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	137	Target Neighborhood Hits	1382	Shared Neighborhood Hits	6
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).