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Network neighborhood for query Sequence : S4A7_HUMAN

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S4A7_HUMAN
SwissProt Accessions	Q9Y6M7, O60350, Q6AHZ9, Q9HC88, Q9UIB9	Gene names	SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

B3A4_HUMAN
θ value	0 (rank : 1)	NC score	0.986831 (rank : 7)
Query Neighborhood Hits	55	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q96Q91, Q96RM5, Q9BXF2, Q9BXN3	Gene names	SLC4A9, AE4, SBC5
Domain Architecture
Description	Anion exchange protein 4 (Anion exchanger 4) (Solute carrier family 4 member 9) (Sodium bicarbonate cotransporter 5).

S4A10_HUMAN
θ value	0 (rank : 2)	NC score	0.994911 (rank : 3)
Query Neighborhood Hits	55	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q6U841, Q4ZFX6, Q8TCP2, Q9HCQ6	Gene names	SLC4A10, NCBE
Domain Architecture	No domain graphic available
Description	Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10).

S4A10_MOUSE
θ value	0 (rank : 3)	NC score	0.995065 (rank : 2)
Query Neighborhood Hits	55	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q5DTL9, Q8CFS3, Q9EST0	Gene names	Slc4a10, Kiaa4136, Ncbe
Domain Architecture	No domain graphic available
Description	Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10).

S4A4_HUMAN
θ value	0 (rank : 4)	NC score	0.988822 (rank : 6)
Query Neighborhood Hits	55	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6R1, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50	Gene names	SLC4A4, NBC, NBC1, NBCE1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1).

S4A4_MOUSE
θ value	0 (rank : 5)	NC score	0.988987 (rank : 5)
Query Neighborhood Hits	55	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	O88343, Q3USE4, Q8BUG0, Q8QZR9, Q9R1C4	Gene names	Slc4a4, Nbc1, Nbce1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4).

S4A7_HUMAN
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	55	Target Neighborhood Hits	55	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6M7, O60350, Q6AHZ9, Q9HC88, Q9UIB9	Gene names	SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7).

S4A7_MOUSE
θ value	0 (rank : 7)	NC score	0.994027 (rank : 4)
Query Neighborhood Hits	55	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BTY2, Q3U5H7	Gene names	Slc4a7, Nbc3
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7).

B3A2_MOUSE
θ value	4.72459e-150 (rank : 8)	NC score	0.965125 (rank : 9)
Query Neighborhood Hits	55	Target Neighborhood Hits	64	Shared Neighborhood Hits	16
SwissProt Accessions	P13808, Q9ES09, Q9ES10, Q9ES11, Q9ES12, Q9ES13	Gene names	Slc4a2, Ae2
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (B3RP).

B3A2_HUMAN
θ value	2.59246e-148 (rank : 9)	NC score	0.966791 (rank : 8)
Query Neighborhood Hits	55	Target Neighborhood Hits	57	Shared Neighborhood Hits	15
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

B3A3_HUMAN
θ value	1.42253e-146 (rank : 10)	NC score	0.961967 (rank : 13)
Query Neighborhood Hits	55	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

B3A3_MOUSE
θ value	4.13891e-146 (rank : 11)	NC score	0.963195 (rank : 12)
Query Neighborhood Hits	55	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

B3AT_HUMAN
θ value	2.60451e-132 (rank : 12)	NC score	0.965067 (rank : 10)
Query Neighborhood Hits	55	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	P02730, P78487, Q4VB84	Gene names	SLC4A1, AE1, DI, EPB3
Domain Architecture
Description	Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Solute carrier family 4 member 1) (CD233 antigen).

B3AT_MOUSE
θ value	6.44497e-115 (rank : 13)	NC score	0.963665 (rank : 11)
Query Neighborhood Hits	55	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P04919	Gene names	Slc4a1, Ae1
Domain Architecture
Description	Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Solute carrier family 4 member 1) (MEB3) (CD233 antigen).

S4A11_HUMAN
θ value	2.26182e-43 (rank : 14)	NC score	0.913970 (rank : 14)
Query Neighborhood Hits	55	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBS3, Q9BXF4, Q9NTW9	Gene names	SLC4A11, BTR1
Domain Architecture
Description	Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Solute carrier family 4 member 11).

PKHF2_MOUSE
θ value	0.0736092 (rank : 15)	NC score	0.057925 (rank : 15)
Query Neighborhood Hits	55	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHF2_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.052743 (rank : 16)
Query Neighborhood Hits	55	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

P2Y14_MOUSE
θ value	0.21417 (rank : 17)	NC score	0.004868 (rank : 50)
Query Neighborhood Hits	55	Target Neighborhood Hits	520	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESG6	Gene names	P2ry14, Gpr105
Domain Architecture
Description	P2Y purinoceptor 14 (P2Y14) (UDP-glucose receptor) (G-protein coupled receptor 105).

GON4L_HUMAN
θ value	0.279714 (rank : 18)	NC score	0.018918 (rank : 24)
Query Neighborhood Hits	55	Target Neighborhood Hits	555	Shared Neighborhood Hits	10
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

ABCA5_MOUSE
θ value	0.47712 (rank : 19)	NC score	0.007511 (rank : 44)
Query Neighborhood Hits	55	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

CENPF_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.002111 (rank : 53)
Query Neighborhood Hits	55	Target Neighborhood Hits	1932	Shared Neighborhood Hits	8
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

NCKX2_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.024460 (rank : 20)
Query Neighborhood Hits	55	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UI40, Q9NTN5, Q9NZQ4	Gene names	SLC24A2, NCKX2
Domain Architecture
Description	Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2).

NFH_MOUSE
θ value	0.62314 (rank : 22)	NC score	0.008528 (rank : 38)
Query Neighborhood Hits	55	Target Neighborhood Hits	2247	Shared Neighborhood Hits	21
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TCF20_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.016361 (rank : 26)
Query Neighborhood Hits	55	Target Neighborhood Hits	396	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

KCT2_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.023530 (rank : 22)
Query Neighborhood Hits	55	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NC54, Q9NRG2	Gene names	KCT2, C5orf15
Domain Architecture	No domain graphic available
Description	Keratinocytes-associated transmembrane protein 2 precursor.

TGIF2_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.011920 (rank : 32)
Query Neighborhood Hits	55	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0Y1	Gene names	Tgif2
Domain Architecture	No domain graphic available
Description	Homeobox protein TGIF2 (TGFB-induced factor 2) (5'-TG-3'-interacting factor 2) (TGF(beta)-induced transcription factor 2).

CO027_MOUSE
θ value	1.81305 (rank : 26)	NC score	0.025591 (rank : 19)
Query Neighborhood Hits	55	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZB3, Q6NVG3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf27 homolog.

PSMD2_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.019148 (rank : 23)
Query Neighborhood Hits	55	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q13200, Q12932, Q15321, Q96I12	Gene names	PSMD2, TRAP2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Tumor necrosis factor type 1 receptor- associated protein 2) (55.11 protein).

CO027_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.024189 (rank : 21)
Query Neighborhood Hits	55	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q2M3C6, Q8N993, Q96LL5	Gene names	C15orf27
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf27.

MDC1_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.015573 (rank : 27)
Query Neighborhood Hits	55	Target Neighborhood Hits	998	Shared Neighborhood Hits	16
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PKHF1_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.034222 (rank : 18)
Query Neighborhood Hits	55	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

PKHF1_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.034365 (rank : 17)
Query Neighborhood Hits	55	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

ZN185_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.014919 (rank : 28)
Query Neighborhood Hits	55	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

ALK_MOUSE
θ value	4.03905 (rank : 33)	NC score	-0.001189 (rank : 55)
Query Neighborhood Hits	55	Target Neighborhood Hits	811	Shared Neighborhood Hits	4
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

SRRM2_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.009692 (rank : 33)
Query Neighborhood Hits	55	Target Neighborhood Hits	1296	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SRRM2_MOUSE
θ value	4.03905 (rank : 35)	NC score	0.008653 (rank : 37)
Query Neighborhood Hits	55	Target Neighborhood Hits	1470	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BAZ2A_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.004928 (rank : 49)
Query Neighborhood Hits	55	Target Neighborhood Hits	744	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

NCOA6_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.004855 (rank : 51)
Query Neighborhood Hits	55	Target Neighborhood Hits	1076	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

IL6RB_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.005455 (rank : 47)
Query Neighborhood Hits	55	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.006043 (rank : 46)
Query Neighborhood Hits	55	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

K1219_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.008082 (rank : 40)
Query Neighborhood Hits	55	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

KAD7_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.007821 (rank : 41)
Query Neighborhood Hits	55	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2H2, Q8BVH3	Gene names	Ak7
Domain Architecture
Description	Putative adenylate kinase 7 (EC 2.7.4.3).

NEST_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.002103 (rank : 54)
Query Neighborhood Hits	55	Target Neighborhood Hits	1305	Shared Neighborhood Hits	11
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PI52B_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.005121 (rank : 48)
Query Neighborhood Hits	55	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P78356, Q5U0E8, Q8TBP2	Gene names	PIP5K2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

TR13C_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.014034 (rank : 30)
Query Neighborhood Hits	55	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RJ3	Gene names	TNFRSF13C, BAFFR, BR3
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13C (B cell- activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD268 antigen).

ALMS1_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.007669 (rank : 43)
Query Neighborhood Hits	55	Target Neighborhood Hits	356	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

MA1B1_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.017623 (rank : 25)
Query Neighborhood Hits	55	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MLL2_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.007734 (rank : 42)
Query Neighborhood Hits	55	Target Neighborhood Hits	1788	Shared Neighborhood Hits	19
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYST4_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.003496 (rank : 52)
Query Neighborhood Hits	55	Target Neighborhood Hits	671	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PPRB_MOUSE
θ value	8.99809 (rank : 49)	NC score	0.008155 (rank : 39)
Query Neighborhood Hits	55	Target Neighborhood Hits	354	Shared Neighborhood Hits	11
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RBM8A_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.009440 (rank : 34)
Query Neighborhood Hits	55	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5S9, Q6FHD1, Q9GZX8, Q9NZI4	Gene names	RBM8A, RBM8
Domain Architecture
Description	RNA-binding protein 8A (RNA-binding motif protein 8A) (Ribonucleoprotein RBM8A) (RNA-binding protein Y14) (Binder of OVCA1- 1) (BOV-1).

RBM8A_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.009440 (rank : 35)
Query Neighborhood Hits	55	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CWZ3, Q9D6U5	Gene names	Rbm8a, Rbm8
Domain Architecture
Description	RNA-binding protein 8A (RNA-binding motif protein 8A) (Ribonucleoprotein RBM8A).

SIN3B_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.006817 (rank : 45)
Query Neighborhood Hits	55	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q62141, O54976, Q6A013, Q8VCB8, Q8VDZ5	Gene names	Sin3b, Kiaa0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

SNIP_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.009103 (rank : 36)
Query Neighborhood Hits	55	Target Neighborhood Hits	313	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SNIP_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.014711 (rank : 29)
Query Neighborhood Hits	55	Target Neighborhood Hits	319	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

VKGC_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.012677 (rank : 31)
Query Neighborhood Hits	55	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P38435, Q14415, Q6GU45	Gene names	GGCX, GC
Domain Architecture
Description	Vitamin K-dependent gamma-carboxylase (EC 6.4.-.-) (Gamma-glutamyl carboxylase) (Vitamin K gamma glutamyl carboxylase).

Hits sorted by NC score

S4A7_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	55	Target Neighborhood Hits	55	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6M7, O60350, Q6AHZ9, Q9HC88, Q9UIB9	Gene names	SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7).

S4A10_MOUSE
NC score	0.995065 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	55	Target Neighborhood Hits	23	Shared Neighborhood Hits	18
SwissProt Accessions	Q5DTL9, Q8CFS3, Q9EST0	Gene names	Slc4a10, Kiaa4136, Ncbe
Domain Architecture	No domain graphic available
Description	Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10).

S4A10_HUMAN
NC score	0.994911 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	55	Target Neighborhood Hits	33	Shared Neighborhood Hits	18
SwissProt Accessions	Q6U841, Q4ZFX6, Q8TCP2, Q9HCQ6	Gene names	SLC4A10, NCBE
Domain Architecture	No domain graphic available
Description	Sodium-driven chloride bicarbonate exchanger (Solute carrier family 4 member 10).

S4A7_MOUSE
NC score	0.994027 (rank : 4)	θ value	0 (rank : 7)
Query Neighborhood Hits	55	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BTY2, Q3U5H7	Gene names	Slc4a7, Nbc3
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Solute carrier family 4 member 7).

S4A4_MOUSE
NC score	0.988987 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	55	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	O88343, Q3USE4, Q8BUG0, Q8QZR9, Q9R1C4	Gene names	Slc4a4, Nbc1, Nbce1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4).

S4A4_HUMAN
NC score	0.988822 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	55	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6R1, O15153, Q8NEJ2, Q9H262, Q9NRZ1, Q9UIC0, Q9UIC1, Q9UP50	Gene names	SLC4A4, NBC, NBC1, NBCE1
Domain Architecture	No domain graphic available
Description	Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1).

B3A4_HUMAN
NC score	0.986831 (rank : 7)	θ value	0 (rank : 1)
Query Neighborhood Hits	55	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q96Q91, Q96RM5, Q9BXF2, Q9BXN3	Gene names	SLC4A9, AE4, SBC5
Domain Architecture
Description	Anion exchange protein 4 (Anion exchanger 4) (Solute carrier family 4 member 9) (Sodium bicarbonate cotransporter 5).

B3A2_HUMAN
NC score	0.966791 (rank : 8)	θ value	2.59246e-148 (rank : 9)
Query Neighborhood Hits	55	Target Neighborhood Hits	57	Shared Neighborhood Hits	15
SwissProt Accessions	P04920, Q45EY5, Q969L3	Gene names	SLC4A2, AE2, EPB3L1, HKB3, MPB3L
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (BND3L).

B3A2_MOUSE
NC score	0.965125 (rank : 9)	θ value	4.72459e-150 (rank : 8)
Query Neighborhood Hits	55	Target Neighborhood Hits	64	Shared Neighborhood Hits	16
SwissProt Accessions	P13808, Q9ES09, Q9ES10, Q9ES11, Q9ES12, Q9ES13	Gene names	Slc4a2, Ae2
Domain Architecture
Description	Anion exchange protein 2 (Non-erythroid band 3-like protein) (AE2 anion exchanger) (Solute carrier family 4 member 2) (B3RP).

B3AT_HUMAN
NC score	0.965067 (rank : 10)	θ value	2.60451e-132 (rank : 12)
Query Neighborhood Hits	55	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	P02730, P78487, Q4VB84	Gene names	SLC4A1, AE1, DI, EPB3
Domain Architecture
Description	Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Solute carrier family 4 member 1) (CD233 antigen).

B3AT_MOUSE
NC score	0.963665 (rank : 11)	θ value	6.44497e-115 (rank : 13)
Query Neighborhood Hits	55	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	P04919	Gene names	Slc4a1, Ae1
Domain Architecture
Description	Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Solute carrier family 4 member 1) (MEB3) (CD233 antigen).

B3A3_MOUSE
NC score	0.963195 (rank : 12)	θ value	4.13891e-146 (rank : 11)
Query Neighborhood Hits	55	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	P16283	Gene names	Slc4a3, Ae3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3).

B3A3_HUMAN
NC score	0.961967 (rank : 13)	θ value	1.42253e-146 (rank : 10)
Query Neighborhood Hits	55	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	P48751	Gene names	SLC4A3, AE3
Domain Architecture
Description	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3).

S4A11_HUMAN
NC score	0.913970 (rank : 14)	θ value	2.26182e-43 (rank : 14)
Query Neighborhood Hits	55	Target Neighborhood Hits	23	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBS3, Q9BXF4, Q9NTW9	Gene names	SLC4A11, BTR1
Domain Architecture
Description	Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Solute carrier family 4 member 11).

PKHF2_MOUSE
NC score	0.057925 (rank : 15)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	55	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WB4	Gene names	Plekhf2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2).

PKHF2_HUMAN
NC score	0.052743 (rank : 16)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	55	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8W4	Gene names	PLEKHF2, ZFYVE18
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 2 (PH domain- containing family F member 2) (PH and FYVE domain-containing protein 2) (Phafin-2) (Zinc finger FYVE domain-containing protein 18).

PKHF1_MOUSE
NC score	0.034365 (rank : 17)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	55	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q3TB82, Q99M16	Gene names	Plekhf1, Lapf
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains).

PKHF1_HUMAN
NC score	0.034222 (rank : 18)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	55	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q96S99, Q96K11, Q9BUB9	Gene names	PLEKHF1, APPD, LAPF, ZFYVE15
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family F member 1 (PH domain- containing family F member 1) (PH and FYVE domain-containing protein 1) (Phafin-1) (Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains) (Apoptosis-inducing protein) (Zinc finger FYVE domain-containing protein 15).

CO027_MOUSE
NC score	0.025591 (rank : 19)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	55	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZB3, Q6NVG3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf27 homolog.

NCKX2_HUMAN
NC score	0.024460 (rank : 20)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	55	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UI40, Q9NTN5, Q9NZQ4	Gene names	SLC24A2, NCKX2
Domain Architecture
Description	Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)- exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2).

CO027_HUMAN
NC score	0.024189 (rank : 21)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	55	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q2M3C6, Q8N993, Q96LL5	Gene names	C15orf27
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf27.

KCT2_HUMAN
NC score	0.023530 (rank : 22)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	55	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NC54, Q9NRG2	Gene names	KCT2, C5orf15
Domain Architecture	No domain graphic available
Description	Keratinocytes-associated transmembrane protein 2 precursor.

PSMD2_HUMAN
NC score	0.019148 (rank : 23)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	55	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q13200, Q12932, Q15321, Q96I12	Gene names	PSMD2, TRAP2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Tumor necrosis factor type 1 receptor- associated protein 2) (55.11 protein).

GON4L_HUMAN
NC score	0.018918 (rank : 24)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	55	Target Neighborhood Hits	555	Shared Neighborhood Hits	10
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MA1B1_HUMAN
NC score	0.017623 (rank : 25)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	55	Target Neighborhood Hits	125	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

TCF20_MOUSE
NC score	0.016361 (rank : 26)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	55	Target Neighborhood Hits	396	Shared Neighborhood Hits	11
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

MDC1_MOUSE
NC score	0.015573 (rank : 27)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	55	Target Neighborhood Hits	998	Shared Neighborhood Hits	16
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ZN185_HUMAN
NC score	0.014919 (rank : 28)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	55	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

SNIP_MOUSE
NC score	0.014711 (rank : 29)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	55	Target Neighborhood Hits	319	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QWI6, O70298	Gene names	P140, Kiaa1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

TR13C_HUMAN
NC score	0.014034 (rank : 30)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	55	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RJ3	Gene names	TNFRSF13C, BAFFR, BR3
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13C (B cell- activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD268 antigen).

VKGC_HUMAN
NC score	0.012677 (rank : 31)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	55	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P38435, Q14415, Q6GU45	Gene names	GGCX, GC
Domain Architecture
Description	Vitamin K-dependent gamma-carboxylase (EC 6.4.-.-) (Gamma-glutamyl carboxylase) (Vitamin K gamma glutamyl carboxylase).

TGIF2_MOUSE
NC score	0.011920 (rank : 32)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	55	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0Y1	Gene names	Tgif2
Domain Architecture	No domain graphic available
Description	Homeobox protein TGIF2 (TGFB-induced factor 2) (5'-TG-3'-interacting factor 2) (TGF(beta)-induced transcription factor 2).

SRRM2_HUMAN
NC score	0.009692 (rank : 33)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	55	Target Neighborhood Hits	1296	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

RBM8A_HUMAN
NC score	0.009440 (rank : 34)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	55	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y5S9, Q6FHD1, Q9GZX8, Q9NZI4	Gene names	RBM8A, RBM8
Domain Architecture
Description	RNA-binding protein 8A (RNA-binding motif protein 8A) (Ribonucleoprotein RBM8A) (RNA-binding protein Y14) (Binder of OVCA1- 1) (BOV-1).

RBM8A_MOUSE
NC score	0.009440 (rank : 35)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	55	Target Neighborhood Hits	198	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CWZ3, Q9D6U5	Gene names	Rbm8a, Rbm8
Domain Architecture
Description	RNA-binding protein 8A (RNA-binding motif protein 8A) (Ribonucleoprotein RBM8A).

SNIP_HUMAN
NC score	0.009103 (rank : 36)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	55	Target Neighborhood Hits	313	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SRRM2_MOUSE
NC score	0.008653 (rank : 37)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	55	Target Neighborhood Hits	1470	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

NFH_MOUSE
NC score	0.008528 (rank : 38)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	55	Target Neighborhood Hits	2247	Shared Neighborhood Hits	21
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PPRB_MOUSE
NC score	0.008155 (rank : 39)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	55	Target Neighborhood Hits	354	Shared Neighborhood Hits	11
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

K1219_HUMAN
NC score	0.008082 (rank : 40)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	55	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

KAD7_MOUSE
NC score	0.007821 (rank : 41)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	55	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2H2, Q8BVH3	Gene names	Ak7
Domain Architecture
Description	Putative adenylate kinase 7 (EC 2.7.4.3).

MLL2_HUMAN
NC score	0.007734 (rank : 42)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	55	Target Neighborhood Hits	1788	Shared Neighborhood Hits	19
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ALMS1_HUMAN
NC score	0.007669 (rank : 43)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	55	Target Neighborhood Hits	356	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

ABCA5_MOUSE
NC score	0.007511 (rank : 44)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	55	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K448, Q3TE17, Q3UUB4, Q6P1Y0, Q6ZPG4, Q810C7, Q8BM46, Q8BXG7	Gene names	Abca5, Kiaa1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

SIN3B_MOUSE
NC score	0.006817 (rank : 45)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	55	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q62141, O54976, Q6A013, Q8VCB8, Q8VDZ5	Gene names	Sin3b, Kiaa0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

IL6RB_MOUSE
NC score	0.006043 (rank : 46)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	55	Target Neighborhood Hits	168	Shared Neighborhood Hits	3
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

IL6RB_HUMAN
NC score	0.005455 (rank : 47)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	55	Target Neighborhood Hits	181	Shared Neighborhood Hits	4
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

PI52B_HUMAN
NC score	0.005121 (rank : 48)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	55	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	P78356, Q5U0E8, Q8TBP2	Gene names	PIP5K2B
Domain Architecture
Description	Phosphatidylinositol-4-phosphate 5-kinase type-2 beta (EC 2.7.1.68) (Phosphatidylinositol-4-phosphate 5-kinase type II beta) (1- phosphatidylinositol-4-phosphate 5-kinase 2-beta) (PtdIns(4)P-5-kinase isoform 2-beta) (PIP5KII-beta) (Diphosphoinositide kinase 2-beta).

BAZ2A_MOUSE
NC score	0.004928 (rank : 49)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	55	Target Neighborhood Hits	744	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

P2Y14_MOUSE
NC score	0.004868 (rank : 50)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	55	Target Neighborhood Hits	520	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESG6	Gene names	P2ry14, Gpr105
Domain Architecture
Description	P2Y purinoceptor 14 (P2Y14) (UDP-glucose receptor) (G-protein coupled receptor 105).

NCOA6_MOUSE
NC score	0.004855 (rank : 51)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	55	Target Neighborhood Hits	1076	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MYST4_HUMAN
NC score	0.003496 (rank : 52)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	55	Target Neighborhood Hits	671	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

CENPF_HUMAN
NC score	0.002111 (rank : 53)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	55	Target Neighborhood Hits	1932	Shared Neighborhood Hits	8
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

NEST_HUMAN
NC score	0.002103 (rank : 54)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	55	Target Neighborhood Hits	1305	Shared Neighborhood Hits	11
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

ALK_MOUSE
NC score	-0.001189 (rank : 55)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	55	Target Neighborhood Hits	811	Shared Neighborhood Hits	4
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).