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Network neighborhood for query Sequence : IL6RB_HUMAN

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IL6RB_HUMAN
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IL6RB_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	181
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
θ value	0 (rank : 2)	NC score	0.969500 (rank : 2)
Query Neighborhood Hits	181	Target Neighborhood Hits	168	Shared Neighborhood Hits	147
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

CSF3R_HUMAN
θ value	8.26713e-62 (rank : 3)	NC score	0.810442 (rank : 3)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	97
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CSF3R_MOUSE
θ value	6.35935e-46 (rank : 4)	NC score	0.777664 (rank : 7)
Query Neighborhood Hits	181	Target Neighborhood Hits	104	Shared Neighborhood Hits	81
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

LIFR_HUMAN
θ value	1.12253e-42 (rank : 5)	NC score	0.781588 (rank : 6)
Query Neighborhood Hits	181	Target Neighborhood Hits	130	Shared Neighborhood Hits	104
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

I12R2_HUMAN
θ value	5.21438e-40 (rank : 6)	NC score	0.803324 (rank : 4)
Query Neighborhood Hits	181	Target Neighborhood Hits	163	Shared Neighborhood Hits	111
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
θ value	1.51715e-39 (rank : 7)	NC score	0.801040 (rank : 5)
Query Neighborhood Hits	181	Target Neighborhood Hits	143	Shared Neighborhood Hits	112
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

LIFR_MOUSE
θ value	4.568e-36 (rank : 8)	NC score	0.757222 (rank : 8)
Query Neighborhood Hits	181	Target Neighborhood Hits	127	Shared Neighborhood Hits	94
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

CRLF1_MOUSE
θ value	2.05525e-28 (rank : 9)	NC score	0.707750 (rank : 9)
Query Neighborhood Hits	181	Target Neighborhood Hits	116	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CRLF1_HUMAN
θ value	1.02001e-27 (rank : 10)	NC score	0.704479 (rank : 10)
Query Neighborhood Hits	181	Target Neighborhood Hits	122	Shared Neighborhood Hits	98
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

LEPR_MOUSE
θ value	4.28545e-26 (rank : 11)	NC score	0.601472 (rank : 11)
Query Neighborhood Hits	181	Target Neighborhood Hits	109	Shared Neighborhood Hits	77
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

LEPR_HUMAN
θ value	4.9032e-22 (rank : 12)	NC score	0.577918 (rank : 12)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	79
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

PRLR_MOUSE
θ value	1.24977e-17 (rank : 13)	NC score	0.523898 (rank : 14)
Query Neighborhood Hits	181	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

PTPRD_HUMAN
θ value	5.8054e-15 (rank : 14)	NC score	0.411910 (rank : 54)
Query Neighborhood Hits	181	Target Neighborhood Hits	485	Shared Neighborhood Hits	137
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

I27RA_HUMAN
θ value	9.90251e-15 (rank : 15)	NC score	0.524973 (rank : 13)
Query Neighborhood Hits	181	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

PTPRD_MOUSE
θ value	2.88119e-14 (rank : 16)	NC score	0.409809 (rank : 55)
Query Neighborhood Hits	181	Target Neighborhood Hits	491	Shared Neighborhood Hits	136
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

I27RA_MOUSE
θ value	1.86753e-13 (rank : 17)	NC score	0.509799 (rank : 16)
Query Neighborhood Hits	181	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

SDK2_MOUSE
θ value	1.86753e-13 (rank : 18)	NC score	0.495890 (rank : 17)
Query Neighborhood Hits	181	Target Neighborhood Hits	480	Shared Neighborhood Hits	135
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

PTPRF_HUMAN
θ value	3.18553e-13 (rank : 19)	NC score	0.396295 (rank : 61)
Query Neighborhood Hits	181	Target Neighborhood Hits	489	Shared Neighborhood Hits	130
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

NRCAM_HUMAN
θ value	7.09661e-13 (rank : 20)	NC score	0.472570 (rank : 21)
Query Neighborhood Hits	181	Target Neighborhood Hits	439	Shared Neighborhood Hits	127
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	7.09661e-13 (rank : 21)	NC score	0.461318 (rank : 24)
Query Neighborhood Hits	181	Target Neighborhood Hits	432	Shared Neighborhood Hits	123
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

PRLR_HUMAN
θ value	7.09661e-13 (rank : 22)	NC score	0.514468 (rank : 15)
Query Neighborhood Hits	181	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

SDK1_HUMAN
θ value	7.09661e-13 (rank : 23)	NC score	0.490192 (rank : 20)
Query Neighborhood Hits	181	Target Neighborhood Hits	511	Shared Neighborhood Hits	136
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
θ value	7.09661e-13 (rank : 24)	NC score	0.493457 (rank : 19)
Query Neighborhood Hits	181	Target Neighborhood Hits	495	Shared Neighborhood Hits	138
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_MOUSE
θ value	2.69671e-12 (rank : 25)	NC score	0.494431 (rank : 18)
Query Neighborhood Hits	181	Target Neighborhood Hits	495	Shared Neighborhood Hits	135
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

CNTFR_MOUSE
θ value	1.74796e-11 (rank : 26)	NC score	0.445075 (rank : 31)
Query Neighborhood Hits	181	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	O88507, Q80T01	Gene names	Cntfr
Domain Architecture	No domain graphic available
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

CNTFR_HUMAN
θ value	3.89403e-11 (rank : 27)	NC score	0.441930 (rank : 32)
Query Neighborhood Hits	181	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	P26992	Gene names	CNTFR
Domain Architecture
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

CNTN3_MOUSE
θ value	2.52405e-10 (rank : 28)	NC score	0.447243 (rank : 28)
Query Neighborhood Hits	181	Target Neighborhood Hits	447	Shared Neighborhood Hits	127
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

TITIN_HUMAN
θ value	2.13673e-09 (rank : 29)	NC score	0.246518 (rank : 113)
Query Neighborhood Hits	181	Target Neighborhood Hits	2923	Shared Neighborhood Hits	152
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CNTN4_HUMAN
θ value	2.79066e-09 (rank : 30)	NC score	0.415989 (rank : 49)
Query Neighborhood Hits	181	Target Neighborhood Hits	449	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN5_HUMAN
θ value	2.79066e-09 (rank : 31)	NC score	0.421451 (rank : 44)
Query Neighborhood Hits	181	Target Neighborhood Hits	446	Shared Neighborhood Hits	124
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

USH2A_HUMAN
θ value	1.06045e-08 (rank : 32)	NC score	0.334045 (rank : 79)
Query Neighborhood Hits	181	Target Neighborhood Hits	600	Shared Neighborhood Hits	128
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

DSCAM_HUMAN
θ value	1.38499e-08 (rank : 33)	NC score	0.439636 (rank : 35)
Query Neighborhood Hits	181	Target Neighborhood Hits	524	Shared Neighborhood Hits	131
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

EPHA8_HUMAN
θ value	1.38499e-08 (rank : 34)	NC score	0.177553 (rank : 195)
Query Neighborhood Hits	181	Target Neighborhood Hits	956	Shared Neighborhood Hits	117
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
θ value	1.38499e-08 (rank : 35)	NC score	0.180231 (rank : 185)
Query Neighborhood Hits	181	Target Neighborhood Hits	969	Shared Neighborhood Hits	117
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

CNTN3_HUMAN
θ value	1.80886e-08 (rank : 36)	NC score	0.448721 (rank : 27)
Query Neighborhood Hits	181	Target Neighborhood Hits	455	Shared Neighborhood Hits	126
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN4_MOUSE
θ value	2.36244e-08 (rank : 37)	NC score	0.415402 (rank : 50)
Query Neighborhood Hits	181	Target Neighborhood Hits	445	Shared Neighborhood Hits	115
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

IL6RA_HUMAN
θ value	3.08544e-08 (rank : 38)	NC score	0.424747 (rank : 43)
Query Neighborhood Hits	181	Target Neighborhood Hits	96	Shared Neighborhood Hits	48
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

USH2A_MOUSE
θ value	4.0297e-08 (rank : 39)	NC score	0.322645 (rank : 83)
Query Neighborhood Hits	181	Target Neighborhood Hits	626	Shared Neighborhood Hits	128
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

PTPRS_HUMAN
θ value	5.26297e-08 (rank : 40)	NC score	0.380338 (rank : 63)
Query Neighborhood Hits	181	Target Neighborhood Hits	472	Shared Neighborhood Hits	128
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

I13R1_HUMAN
θ value	6.87365e-08 (rank : 41)	NC score	0.274481 (rank : 97)
Query Neighborhood Hits	181	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

NEO1_HUMAN
θ value	6.87365e-08 (rank : 42)	NC score	0.467923 (rank : 23)
Query Neighborhood Hits	181	Target Neighborhood Hits	530	Shared Neighborhood Hits	136
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	6.87365e-08 (rank : 43)	NC score	0.468349 (rank : 22)
Query Neighborhood Hits	181	Target Neighborhood Hits	523	Shared Neighborhood Hits	136
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

MYOM1_HUMAN
θ value	1.99992e-07 (rank : 44)	NC score	0.441837 (rank : 33)
Query Neighborhood Hits	181	Target Neighborhood Hits	405	Shared Neighborhood Hits	122
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

IL6RA_MOUSE
θ value	2.61198e-07 (rank : 45)	NC score	0.434478 (rank : 38)
Query Neighborhood Hits	181	Target Neighborhood Hits	104	Shared Neighborhood Hits	57
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

COEA1_HUMAN
θ value	4.45536e-07 (rank : 46)	NC score	0.242593 (rank : 115)
Query Neighborhood Hits	181	Target Neighborhood Hits	427	Shared Neighborhood Hits	103
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

DSCL1_HUMAN
θ value	4.45536e-07 (rank : 47)	NC score	0.445769 (rank : 29)
Query Neighborhood Hits	181	Target Neighborhood Hits	589	Shared Neighborhood Hits	132
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

I11RA_HUMAN
θ value	4.45536e-07 (rank : 48)	NC score	0.425151 (rank : 42)
Query Neighborhood Hits	181	Target Neighborhood Hits	138	Shared Neighborhood Hits	59
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

CNTN5_MOUSE
θ value	5.81887e-07 (rank : 49)	NC score	0.416726 (rank : 48)
Query Neighborhood Hits	181	Target Neighborhood Hits	434	Shared Neighborhood Hits	120
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

EPHA7_MOUSE
θ value	5.81887e-07 (rank : 50)	NC score	0.182455 (rank : 179)
Query Neighborhood Hits	181	Target Neighborhood Hits	1025	Shared Neighborhood Hits	117
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

I11RB_MOUSE
θ value	5.81887e-07 (rank : 51)	NC score	0.435183 (rank : 37)
Query Neighborhood Hits	181	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

DCC_HUMAN
θ value	7.59969e-07 (rank : 52)	NC score	0.438954 (rank : 36)
Query Neighborhood Hits	181	Target Neighborhood Hits	583	Shared Neighborhood Hits	131
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

CNTN1_HUMAN
θ value	9.92553e-07 (rank : 53)	NC score	0.417412 (rank : 47)
Query Neighborhood Hits	181	Target Neighborhood Hits	431	Shared Neighborhood Hits	118
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

I11RA_MOUSE
θ value	9.92553e-07 (rank : 54)	NC score	0.426521 (rank : 41)
Query Neighborhood Hits	181	Target Neighborhood Hits	95	Shared Neighborhood Hits	56
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

EPHA7_HUMAN
θ value	1.29631e-06 (rank : 55)	NC score	0.182098 (rank : 181)
Query Neighborhood Hits	181	Target Neighborhood Hits	1053	Shared Neighborhood Hits	116
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

DCC_MOUSE
θ value	1.69304e-06 (rank : 56)	NC score	0.429978 (rank : 40)
Query Neighborhood Hits	181	Target Neighborhood Hits	896	Shared Neighborhood Hits	133
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

COCA1_HUMAN
θ value	2.21117e-06 (rank : 57)	NC score	0.326835 (rank : 82)
Query Neighborhood Hits	181	Target Neighborhood Hits	458	Shared Neighborhood Hits	124
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ROBO2_MOUSE
θ value	6.43352e-06 (rank : 58)	NC score	0.379162 (rank : 64)
Query Neighborhood Hits	181	Target Neighborhood Hits	504	Shared Neighborhood Hits	124
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

COEA1_MOUSE
θ value	8.40245e-06 (rank : 59)	NC score	0.265467 (rank : 101)
Query Neighborhood Hits	181	Target Neighborhood Hits	402	Shared Neighborhood Hits	88
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

CNTN1_MOUSE
θ value	1.09739e-05 (rank : 60)	NC score	0.413759 (rank : 52)
Query Neighborhood Hits	181	Target Neighborhood Hits	422	Shared Neighborhood Hits	115
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN6_HUMAN
θ value	1.09739e-05 (rank : 61)	NC score	0.412934 (rank : 53)
Query Neighborhood Hits	181	Target Neighborhood Hits	422	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

NFASC_MOUSE
θ value	1.09739e-05 (rank : 62)	NC score	0.406220 (rank : 59)
Query Neighborhood Hits	181	Target Neighborhood Hits	475	Shared Neighborhood Hits	122
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

COCA1_MOUSE
θ value	2.44474e-05 (rank : 63)	NC score	0.329632 (rank : 80)
Query Neighborhood Hits	181	Target Neighborhood Hits	467	Shared Neighborhood Hits	131
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ROBO1_HUMAN
θ value	2.44474e-05 (rank : 64)	NC score	0.363971 (rank : 71)
Query Neighborhood Hits	181	Target Neighborhood Hits	529	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

IL7RA_MOUSE
θ value	3.19293e-05 (rank : 65)	NC score	0.217395 (rank : 124)
Query Neighborhood Hits	181	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

L1CAM_HUMAN
θ value	3.19293e-05 (rank : 66)	NC score	0.445217 (rank : 30)
Query Neighborhood Hits	181	Target Neighborhood Hits	457	Shared Neighborhood Hits	128
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

ROBO2_HUMAN
θ value	3.19293e-05 (rank : 67)	NC score	0.375979 (rank : 65)
Query Neighborhood Hits	181	Target Neighborhood Hits	479	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

EPHA6_HUMAN
θ value	4.1701e-05 (rank : 68)	NC score	0.160153 (rank : 235)
Query Neighborhood Hits	181	Target Neighborhood Hits	959	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

IL27B_MOUSE
θ value	4.1701e-05 (rank : 69)	NC score	0.366132 (rank : 68)
Query Neighborhood Hits	181	Target Neighborhood Hits	55	Shared Neighborhood Hits	46
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

EPHA2_MOUSE
θ value	5.44631e-05 (rank : 70)	NC score	0.149074 (rank : 259)
Query Neighborhood Hits	181	Target Neighborhood Hits	1020	Shared Neighborhood Hits	108
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

IL2RG_MOUSE
θ value	5.44631e-05 (rank : 71)	NC score	0.170650 (rank : 216)
Query Neighborhood Hits	181	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL3B2_MOUSE
θ value	5.44631e-05 (rank : 72)	NC score	0.175352 (rank : 199)
Query Neighborhood Hits	181	Target Neighborhood Hits	372	Shared Neighborhood Hits	43
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL7RA_HUMAN
θ value	5.44631e-05 (rank : 73)	NC score	0.252880 (rank : 107)
Query Neighborhood Hits	181	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	P16871, Q6SV45, Q9UPC1	Gene names	IL7R
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen) (CDw127).

MYOM2_HUMAN
θ value	5.44631e-05 (rank : 74)	NC score	0.409576 (rank : 56)
Query Neighborhood Hits	181	Target Neighborhood Hits	341	Shared Neighborhood Hits	115
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

EPHA6_MOUSE
θ value	7.1131e-05 (rank : 75)	NC score	0.155830 (rank : 247)
Query Neighborhood Hits	181	Target Neighborhood Hits	946	Shared Neighborhood Hits	91
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

I13R1_MOUSE
θ value	9.29e-05 (rank : 76)	NC score	0.267985 (rank : 100)
Query Neighborhood Hits	181	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

ROBO1_MOUSE
θ value	9.29e-05 (rank : 77)	NC score	0.366071 (rank : 69)
Query Neighborhood Hits	181	Target Neighborhood Hits	559	Shared Neighborhood Hits	125
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

UFO_MOUSE
θ value	9.29e-05 (rank : 78)	NC score	0.172561 (rank : 206)
Query Neighborhood Hits	181	Target Neighborhood Hits	988	Shared Neighborhood Hits	113
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

EPHA5_MOUSE
θ value	0.000158464 (rank : 79)	NC score	0.149252 (rank : 258)
Query Neighborhood Hits	181	Target Neighborhood Hits	950	Shared Neighborhood Hits	105
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

EPHA4_HUMAN
θ value	0.00020696 (rank : 80)	NC score	0.170844 (rank : 214)
Query Neighborhood Hits	181	Target Neighborhood Hits	975	Shared Neighborhood Hits	109
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

CNTN6_MOUSE
θ value	0.000270298 (rank : 81)	NC score	0.407576 (rank : 58)
Query Neighborhood Hits	181	Target Neighborhood Hits	429	Shared Neighborhood Hits	117
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

IL27B_HUMAN
θ value	0.000270298 (rank : 82)	NC score	0.393168 (rank : 62)
Query Neighborhood Hits	181	Target Neighborhood Hits	80	Shared Neighborhood Hits	66
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

EPHA3_HUMAN
θ value	0.00035302 (rank : 83)	NC score	0.170110 (rank : 218)
Query Neighborhood Hits	181	Target Neighborhood Hits	1005	Shared Neighborhood Hits	122
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA3_MOUSE
θ value	0.00035302 (rank : 84)	NC score	0.174903 (rank : 201)
Query Neighborhood Hits	181	Target Neighborhood Hits	1009	Shared Neighborhood Hits	125
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

CHL1_HUMAN
θ value	0.000461057 (rank : 85)	NC score	0.433142 (rank : 39)
Query Neighborhood Hits	181	Target Neighborhood Hits	413	Shared Neighborhood Hits	121
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

NFASC_HUMAN
θ value	0.000461057 (rank : 86)	NC score	0.420418 (rank : 45)
Query Neighborhood Hits	181	Target Neighborhood Hits	497	Shared Neighborhood Hits	124
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

CDON_HUMAN
θ value	0.000786445 (rank : 87)	NC score	0.367201 (rank : 66)
Query Neighborhood Hits	181	Target Neighborhood Hits	412	Shared Neighborhood Hits	104
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

EPHA2_HUMAN
θ value	0.000786445 (rank : 88)	NC score	0.152093 (rank : 256)
Query Neighborhood Hits	181	Target Neighborhood Hits	1021	Shared Neighborhood Hits	112
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA4_MOUSE
θ value	0.000786445 (rank : 89)	NC score	0.171456 (rank : 210)
Query Neighborhood Hits	181	Target Neighborhood Hits	982	Shared Neighborhood Hits	111
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

I13R2_HUMAN
θ value	0.000786445 (rank : 90)	NC score	0.314129 (rank : 85)
Query Neighborhood Hits	181	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

MYOM1_MOUSE
θ value	0.000786445 (rank : 91)	NC score	0.409151 (rank : 57)
Query Neighborhood Hits	181	Target Neighborhood Hits	415	Shared Neighborhood Hits	127
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

EPHA5_HUMAN
θ value	0.00102713 (rank : 92)	NC score	0.170510 (rank : 217)
Query Neighborhood Hits	181	Target Neighborhood Hits	1009	Shared Neighborhood Hits	115
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

L1CAM_MOUSE
θ value	0.00102713 (rank : 93)	NC score	0.441356 (rank : 34)
Query Neighborhood Hits	181	Target Neighborhood Hits	457	Shared Neighborhood Hits	130
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

SORL_HUMAN
θ value	0.00102713 (rank : 94)	NC score	0.179945 (rank : 187)
Query Neighborhood Hits	181	Target Neighborhood Hits	440	Shared Neighborhood Hits	103
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	0.00102713 (rank : 95)	NC score	0.181100 (rank : 182)
Query Neighborhood Hits	181	Target Neighborhood Hits	439	Shared Neighborhood Hits	106
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TIE1_MOUSE
θ value	0.00102713 (rank : 96)	NC score	0.143979 (rank : 263)
Query Neighborhood Hits	181	Target Neighborhood Hits	1266	Shared Neighborhood Hits	117
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MERTK_MOUSE
θ value	0.00134147 (rank : 97)	NC score	0.168525 (rank : 226)
Query Neighborhood Hits	181	Target Neighborhood Hits	974	Shared Neighborhood Hits	108
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MYLK_HUMAN
θ value	0.00134147 (rank : 98)	NC score	0.159748 (rank : 236)
Query Neighborhood Hits	181	Target Neighborhood Hits	1328	Shared Neighborhood Hits	107
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

CDON_MOUSE
θ value	0.00228821 (rank : 99)	NC score	0.362749 (rank : 72)
Query Neighborhood Hits	181	Target Neighborhood Hits	410	Shared Neighborhood Hits	105
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

INAR1_MOUSE
θ value	0.00228821 (rank : 100)	NC score	0.108797 (rank : 327)
Query Neighborhood Hits	181	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	P33896	Gene names	Ifnar1, Ifar, Ifnar
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

MYLK_MOUSE
θ value	0.00228821 (rank : 101)	NC score	0.157760 (rank : 241)
Query Neighborhood Hits	181	Target Neighborhood Hits	1489	Shared Neighborhood Hits	107
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

IL2RG_HUMAN
θ value	0.00298849 (rank : 102)	NC score	0.164477 (rank : 233)
Query Neighborhood Hits	181	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

CNTN2_HUMAN
θ value	0.00509761 (rank : 103)	NC score	0.415130 (rank : 51)
Query Neighborhood Hits	181	Target Neighborhood Hits	440	Shared Neighborhood Hits	120
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

EPHB2_HUMAN
θ value	0.00509761 (rank : 104)	NC score	0.154209 (rank : 251)
Query Neighborhood Hits	181	Target Neighborhood Hits	983	Shared Neighborhood Hits	101
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.00509761 (rank : 105)	NC score	0.154197 (rank : 252)
Query Neighborhood Hits	181	Target Neighborhood Hits	982	Shared Neighborhood Hits	101
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

IL4RA_HUMAN
θ value	0.00509761 (rank : 106)	NC score	0.120650 (rank : 303)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	27
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

EPHB1_HUMAN
θ value	0.00665767 (rank : 107)	NC score	0.158649 (rank : 239)
Query Neighborhood Hits	181	Target Neighborhood Hits	988	Shared Neighborhood Hits	110
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

MERTK_HUMAN
θ value	0.00665767 (rank : 108)	NC score	0.171374 (rank : 211)
Query Neighborhood Hits	181	Target Neighborhood Hits	988	Shared Neighborhood Hits	105
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

IL21R_HUMAN
θ value	0.00869519 (rank : 109)	NC score	0.179017 (rank : 190)
Query Neighborhood Hits	181	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

IL3RB_MOUSE
θ value	0.00869519 (rank : 110)	NC score	0.156387 (rank : 245)
Query Neighborhood Hits	181	Target Neighborhood Hits	355	Shared Neighborhood Hits	39
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

PTPRT_HUMAN
θ value	0.00869519 (rank : 111)	NC score	0.211187 (rank : 133)
Query Neighborhood Hits	181	Target Neighborhood Hits	217	Shared Neighborhood Hits	100
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	0.00869519 (rank : 112)	NC score	0.211237 (rank : 132)
Query Neighborhood Hits	181	Target Neighborhood Hits	219	Shared Neighborhood Hits	100
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

UFO_HUMAN
θ value	0.00869519 (rank : 113)	NC score	0.157636 (rank : 242)
Query Neighborhood Hits	181	Target Neighborhood Hits	981	Shared Neighborhood Hits	109
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

IL3RB_HUMAN
θ value	0.0113563 (rank : 114)	NC score	0.187758 (rank : 173)
Query Neighborhood Hits	181	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

EPHB4_HUMAN
θ value	0.0148317 (rank : 115)	NC score	0.155050 (rank : 249)
Query Neighborhood Hits	181	Target Neighborhood Hits	1056	Shared Neighborhood Hits	113
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

NCA11_HUMAN
θ value	0.0193708 (rank : 116)	NC score	0.294558 (rank : 88)
Query Neighborhood Hits	181	Target Neighborhood Hits	443	Shared Neighborhood Hits	102
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NCA12_HUMAN
θ value	0.0193708 (rank : 117)	NC score	0.286070 (rank : 91)
Query Neighborhood Hits	181	Target Neighborhood Hits	437	Shared Neighborhood Hits	97
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

TARSH_HUMAN
θ value	0.0193708 (rank : 118)	NC score	0.201291 (rank : 151)
Query Neighborhood Hits	181	Target Neighborhood Hits	768	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CNTN2_MOUSE
θ value	0.0252991 (rank : 119)	NC score	0.403469 (rank : 60)
Query Neighborhood Hits	181	Target Neighborhood Hits	450	Shared Neighborhood Hits	120
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CO7A1_HUMAN
θ value	0.0252991 (rank : 120)	NC score	0.214676 (rank : 128)
Query Neighborhood Hits	181	Target Neighborhood Hits	807	Shared Neighborhood Hits	113
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

GHR_HUMAN
θ value	0.0252991 (rank : 121)	NC score	0.206711 (rank : 137)
Query Neighborhood Hits	181	Target Neighborhood Hits	57	Shared Neighborhood Hits	31
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

ROS_HUMAN
θ value	0.0252991 (rank : 122)	NC score	0.139354 (rank : 268)
Query Neighborhood Hits	181	Target Neighborhood Hits	907	Shared Neighborhood Hits	116
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

EPOR_MOUSE
θ value	0.0330416 (rank : 123)	NC score	0.180560 (rank : 183)
Query Neighborhood Hits	181	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

PUNC_MOUSE
θ value	0.0330416 (rank : 124)	NC score	0.364973 (rank : 70)
Query Neighborhood Hits	181	Target Neighborhood Hits	501	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

FNDC3_MOUSE
θ value	0.0736092 (rank : 125)	NC score	0.453224 (rank : 25)
Query Neighborhood Hits	181	Target Neighborhood Hits	207	Shared Neighborhood Hits	124
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

NCA11_MOUSE
θ value	0.0736092 (rank : 126)	NC score	0.288114 (rank : 90)
Query Neighborhood Hits	181	Target Neighborhood Hits	661	Shared Neighborhood Hits	102
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PTPRJ_MOUSE
θ value	0.0736092 (rank : 127)	NC score	0.137030 (rank : 273)
Query Neighborhood Hits	181	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

EPHB3_MOUSE
θ value	0.0961366 (rank : 128)	NC score	0.167243 (rank : 227)
Query Neighborhood Hits	181	Target Neighborhood Hits	996	Shared Neighborhood Hits	117
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

FNDC3_HUMAN
θ value	0.0961366 (rank : 129)	NC score	0.453110 (rank : 26)
Query Neighborhood Hits	181	Target Neighborhood Hits	196	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

ROBO3_HUMAN
θ value	0.0961366 (rank : 130)	NC score	0.354181 (rank : 74)
Query Neighborhood Hits	181	Target Neighborhood Hits	570	Shared Neighborhood Hits	119
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

TRI42_HUMAN
θ value	0.0961366 (rank : 131)	NC score	0.083840 (rank : 400)
Query Neighborhood Hits	181	Target Neighborhood Hits	283	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ITB4_HUMAN
θ value	0.125558 (rank : 132)	NC score	0.264867 (rank : 102)
Query Neighborhood Hits	181	Target Neighborhood Hits	458	Shared Neighborhood Hits	117
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

UBP53_MOUSE
θ value	0.125558 (rank : 133)	NC score	0.029514 (rank : 584)
Query Neighborhood Hits	181	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

DUET_HUMAN
θ value	0.163984 (rank : 134)	NC score	0.122084 (rank : 301)
Query Neighborhood Hits	181	Target Neighborhood Hits	1220	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

EPHB4_MOUSE
θ value	0.163984 (rank : 135)	NC score	0.155830 (rank : 246)
Query Neighborhood Hits	181	Target Neighborhood Hits	1013	Shared Neighborhood Hits	110
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

NPHN_MOUSE
θ value	0.163984 (rank : 136)	NC score	0.293920 (rank : 89)
Query Neighborhood Hits	181	Target Neighborhood Hits	370	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

TENX_HUMAN
θ value	0.163984 (rank : 137)	NC score	0.166727 (rank : 229)
Query Neighborhood Hits	181	Target Neighborhood Hits	789	Shared Neighborhood Hits	113
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TRI42_MOUSE
θ value	0.163984 (rank : 138)	NC score	0.070442 (rank : 431)
Query Neighborhood Hits	181	Target Neighborhood Hits	316	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

I10R2_MOUSE
θ value	0.21417 (rank : 139)	NC score	0.068179 (rank : 437)
Query Neighborhood Hits	181	Target Neighborhood Hits	52	Shared Neighborhood Hits	18
SwissProt Accessions	Q61190	Gene names	Il10rb, Crfb4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

MYPC2_MOUSE
θ value	0.21417 (rank : 140)	NC score	0.283614 (rank : 92)
Query Neighborhood Hits	181	Target Neighborhood Hits	297	Shared Neighborhood Hits	95
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

GHR_MOUSE
θ value	0.365318 (rank : 141)	NC score	0.161892 (rank : 234)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	26
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

IL4RA_MOUSE
θ value	0.365318 (rank : 142)	NC score	0.105387 (rank : 338)
Query Neighborhood Hits	181	Target Neighborhood Hits	194	Shared Neighborhood Hits	22
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

BOC_HUMAN
θ value	0.47712 (rank : 143)	NC score	0.343757 (rank : 76)
Query Neighborhood Hits	181	Target Neighborhood Hits	543	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CHL1_MOUSE
θ value	0.47712 (rank : 144)	NC score	0.419623 (rank : 46)
Query Neighborhood Hits	181	Target Neighborhood Hits	402	Shared Neighborhood Hits	115
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CO5_MOUSE
θ value	0.62314 (rank : 145)	NC score	0.020035 (rank : 586)
Query Neighborhood Hits	181	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

EPHB3_HUMAN
θ value	0.62314 (rank : 146)	NC score	0.165164 (rank : 231)
Query Neighborhood Hits	181	Target Neighborhood Hits	996	Shared Neighborhood Hits	114
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

PTPRU_HUMAN
θ value	0.62314 (rank : 147)	NC score	0.201619 (rank : 150)
Query Neighborhood Hits	181	Target Neighborhood Hits	237	Shared Neighborhood Hits	105
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

TENA_HUMAN
θ value	0.62314 (rank : 148)	NC score	0.172995 (rank : 205)
Query Neighborhood Hits	181	Target Neighborhood Hits	631	Shared Neighborhood Hits	113
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENR_HUMAN
θ value	0.62314 (rank : 149)	NC score	0.223538 (rank : 117)
Query Neighborhood Hits	181	Target Neighborhood Hits	526	Shared Neighborhood Hits	112
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ROBO4_HUMAN
θ value	0.813845 (rank : 150)	NC score	0.329033 (rank : 81)
Query Neighborhood Hits	181	Target Neighborhood Hits	364	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

BOC_MOUSE
θ value	1.06291 (rank : 151)	NC score	0.342889 (rank : 78)
Query Neighborhood Hits	181	Target Neighborhood Hits	433	Shared Neighborhood Hits	105
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CO5_HUMAN
θ value	1.06291 (rank : 152)	NC score	0.019642 (rank : 587)
Query Neighborhood Hits	181	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

IF4G3_HUMAN
θ value	1.06291 (rank : 153)	NC score	0.025311 (rank : 585)
Query Neighborhood Hits	181	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

TENN_HUMAN
θ value	1.06291 (rank : 154)	NC score	0.201745 (rank : 149)
Query Neighborhood Hits	181	Target Neighborhood Hits	453	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

NCA12_MOUSE
θ value	1.38821 (rank : 155)	NC score	0.282112 (rank : 94)
Query Neighborhood Hits	181	Target Neighborhood Hits	399	Shared Neighborhood Hits	92
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

TENR_MOUSE
θ value	1.38821 (rank : 156)	NC score	0.216425 (rank : 125)
Query Neighborhood Hits	181	Target Neighborhood Hits	531	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

HCFC1_MOUSE
θ value	1.81305 (rank : 157)	NC score	0.093453 (rank : 380)
Query Neighborhood Hits	181	Target Neighborhood Hits	348	Shared Neighborhood Hits	50
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

PUNC_HUMAN
θ value	2.36792 (rank : 158)	NC score	0.367175 (rank : 67)
Query Neighborhood Hits	181	Target Neighborhood Hits	449	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

STB5L_HUMAN
θ value	2.36792 (rank : 159)	NC score	0.012113 (rank : 592)
Query Neighborhood Hits	181	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

I20RA_MOUSE
θ value	3.0926 (rank : 160)	NC score	0.047746 (rank : 583)
Query Neighborhood Hits	181	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PHB0, Q8BW64	Gene names	Il20ra
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL- 20R1).

RNH2A_HUMAN
θ value	3.0926 (rank : 161)	NC score	0.017348 (rank : 589)
Query Neighborhood Hits	181	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O75792, Q96F11	Gene names	RNASEH2A, RNASEHI, RNHIA
Domain Architecture
Description	Ribonuclease H2 subunit A (EC 3.1.26.4) (RNase H2 subunit A) (Ribonuclease HI subunit A) (Ribonuclease HI large subunit) (RNase HI large subunit) (RNase H(35)) (Aicardi-Goutieres syndrome 4 protein) (AGS4).

FINC_HUMAN
θ value	4.03905 (rank : 162)	NC score	0.349520 (rank : 75)
Query Neighborhood Hits	181	Target Neighborhood Hits	302	Shared Neighborhood Hits	128
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

IL2RB_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.099424 (rank : 357)
Query Neighborhood Hits	181	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

KIF17_HUMAN
θ value	4.03905 (rank : 164)	NC score	0.002146 (rank : 597)
Query Neighborhood Hits	181	Target Neighborhood Hits	365	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

ROBO4_MOUSE
θ value	4.03905 (rank : 165)	NC score	0.316325 (rank : 84)
Query Neighborhood Hits	181	Target Neighborhood Hits	358	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

STB5L_MOUSE
θ value	4.03905 (rank : 166)	NC score	0.011219 (rank : 593)
Query Neighborhood Hits	181	Target Neighborhood Hits	138	Shared Neighborhood Hits	4
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

TPOR_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.142211 (rank : 264)
Query Neighborhood Hits	181	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

DEN2A_MOUSE
θ value	5.27518 (rank : 168)	NC score	0.008016 (rank : 594)
Query Neighborhood Hits	181	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

EPOR_HUMAN
θ value	5.27518 (rank : 169)	NC score	0.159519 (rank : 238)
Query Neighborhood Hits	181	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	P19235, Q15443	Gene names	EPOR
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

FSBP_MOUSE
θ value	5.27518 (rank : 170)	NC score	0.012920 (rank : 591)
Query Neighborhood Hits	181	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BKE5, Q8BJX8	Gene names	Fsbp
Domain Architecture	No domain graphic available
Description	Fibrinogen silencer-binding protein.

PCDGH_HUMAN
θ value	5.27518 (rank : 171)	NC score	-0.001808 (rank : 599)
Query Neighborhood Hits	181	Target Neighborhood Hits	164	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5G0, Q9Y5C6	Gene names	PCDHGB5
Domain Architecture
Description	Protocadherin gamma B5 precursor (PCDH-gamma-B5).

PTPRJ_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.133841 (rank : 283)
Query Neighborhood Hits	181	Target Neighborhood Hits	207	Shared Neighborhood Hits	75
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PXR_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.000824 (rank : 598)
Query Neighborhood Hits	181	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

DEN2A_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.007722 (rank : 595)
Query Neighborhood Hits	181	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

LRP1B_MOUSE
θ value	6.88961 (rank : 175)	NC score	0.019204 (rank : 588)
Query Neighborhood Hits	181	Target Neighborhood Hits	606	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MYPC1_HUMAN
θ value	6.88961 (rank : 176)	NC score	0.256713 (rank : 104)
Query Neighborhood Hits	181	Target Neighborhood Hits	303	Shared Neighborhood Hits	91
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

RL3R1_HUMAN
θ value	6.88961 (rank : 177)	NC score	-0.003246 (rank : 600)
Query Neighborhood Hits	181	Target Neighborhood Hits	507	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NSD7	Gene names	RXFP3, RLN3R1, SALPR
Domain Architecture
Description	Relaxin-3 receptor 1 (RLN3 receptor 1) (Relaxin family peptide receptor 3) (Somatostatin- and angiotensin-like peptide receptor) (G protein-coupled receptor SALPR) (GPCR135).

S4A7_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.005455 (rank : 596)
Query Neighborhood Hits	181	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6M7, O60350, Q6AHZ9, Q9HC88, Q9UIB9	Gene names	SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7).

ALMS1_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.013584 (rank : 590)
Query Neighborhood Hits	181	Target Neighborhood Hits	356	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

MYPC3_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.275832 (rank : 96)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	106
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

ZFY_HUMAN
θ value	8.99809 (rank : 181)	NC score	-0.008019 (rank : 601)
Query Neighborhood Hits	181	Target Neighborhood Hits	752	Shared Neighborhood Hits	2
SwissProt Accessions	P08048, Q14021, Q15558, Q96TF3	Gene names	ZFY
Domain Architecture
Description	Zinc finger Y-chromosomal protein.

AATK_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.057552 (rank : 539)
Query Neighborhood Hits	181	Target Neighborhood Hits	1243	Shared Neighborhood Hits	37
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AATK_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.059059 (rank : 514)
Query Neighborhood Hits	181	Target Neighborhood Hits	942	Shared Neighborhood Hits	32
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ABL1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.057730 (rank : 535)
Query Neighborhood Hits	181	Target Neighborhood Hits	1220	Shared Neighborhood Hits	31
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.058956 (rank : 518)
Query Neighborhood Hits	181	Target Neighborhood Hits	1178	Shared Neighborhood Hits	36
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL2_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.058229 (rank : 526)
Query Neighborhood Hits	181	Target Neighborhood Hits	1045	Shared Neighborhood Hits	31
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ACK1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.065447 (rank : 458)
Query Neighborhood Hits	181	Target Neighborhood Hits	1140	Shared Neighborhood Hits	37
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.065359 (rank : 459)
Query Neighborhood Hits	181	Target Neighborhood Hits	1080	Shared Neighborhood Hits	35
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ALK_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.070294 (rank : 432)
Query Neighborhood Hits	181	Target Neighborhood Hits	795	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.070689 (rank : 430)
Query Neighborhood Hits	181	Target Neighborhood Hits	811	Shared Neighborhood Hits	36
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ANKF1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.095031 (rank : 376)
Query Neighborhood Hits	181	Target Neighborhood Hits	126	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ARAF_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.051341 (rank : 579)
Query Neighborhood Hits	181	Target Neighborhood Hits	924	Shared Neighborhood Hits	31
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.051789 (rank : 574)
Query Neighborhood Hits	181	Target Neighborhood Hits	874	Shared Neighborhood Hits	31
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

ATL3_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.136917 (rank : 275)
Query Neighborhood Hits	181	Target Neighborhood Hits	414	Shared Neighborhood Hits	67
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

BASI_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.187569 (rank : 174)
Query Neighborhood Hits	181	Target Neighborhood Hits	211	Shared Neighborhood Hits	60
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

BASI_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.184820 (rank : 177)
Query Neighborhood Hits	181	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

BLK_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.059365 (rank : 510)
Query Neighborhood Hits	181	Target Neighborhood Hits	994	Shared Neighborhood Hits	31
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.059988 (rank : 493)
Query Neighborhood Hits	181	Target Neighborhood Hits	992	Shared Neighborhood Hits	31
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BMX_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.058637 (rank : 523)
Query Neighborhood Hits	181	Target Neighborhood Hits	942	Shared Neighborhood Hits	31
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.059159 (rank : 512)
Query Neighborhood Hits	181	Target Neighborhood Hits	912	Shared Neighborhood Hits	31
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BRAF1_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.050317 (rank : 581)
Query Neighborhood Hits	181	Target Neighborhood Hits	883	Shared Neighborhood Hits	31
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

BTK_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.059001 (rank : 516)
Query Neighborhood Hits	181	Target Neighborhood Hits	1026	Shared Neighborhood Hits	31
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.058981 (rank : 517)
Query Neighborhood Hits	181	Target Neighborhood Hits	1017	Shared Neighborhood Hits	31
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

CD166_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.120194 (rank : 304)
Query Neighborhood Hits	181	Target Neighborhood Hits	247	Shared Neighborhood Hits	54
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

CD166_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.134019 (rank : 282)
Query Neighborhood Hits	181	Target Neighborhood Hits	252	Shared Neighborhood Hits	56
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

CD22_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.179239 (rank : 189)
Query Neighborhood Hits	181	Target Neighborhood Hits	365	Shared Neighborhood Hits	61
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD22_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.191278 (rank : 167)
Query Neighborhood Hits	181	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD276_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.102023 (rank : 351)
Query Neighborhood Hits	181	Target Neighborhood Hits	261	Shared Neighborhood Hits	42
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.067231 (rank : 439)
Query Neighborhood Hits	181	Target Neighborhood Hits	243	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CD45_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.091342 (rank : 384)
Query Neighborhood Hits	181	Target Neighborhood Hits	243	Shared Neighborhood Hits	43
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.090578 (rank : 387)
Query Neighborhood Hits	181	Target Neighborhood Hits	178	Shared Neighborhood Hits	42
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CD79A_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.079053 (rank : 408)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CEA20_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.171754 (rank : 209)
Query Neighborhood Hits	181	Target Neighborhood Hits	251	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

CEAM1_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.148919 (rank : 260)
Query Neighborhood Hits	181	Target Neighborhood Hits	348	Shared Neighborhood Hits	64
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

CEAM1_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.169092 (rank : 222)
Query Neighborhood Hits	181	Target Neighborhood Hits	326	Shared Neighborhood Hits	64
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

CEAM5_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.178084 (rank : 193)
Query Neighborhood Hits	181	Target Neighborhood Hits	343	Shared Neighborhood Hits	66
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

CEAM6_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.128026 (rank : 292)
Query Neighborhood Hits	181	Target Neighborhood Hits	308	Shared Neighborhood Hits	65
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

CEAM7_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.072624 (rank : 423)
Query Neighborhood Hits	181	Target Neighborhood Hits	170	Shared Neighborhood Hits	51
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

CEAM8_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.107611 (rank : 332)
Query Neighborhood Hits	181	Target Neighborhood Hits	264	Shared Neighborhood Hits	62
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

CI094_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.190775 (rank : 168)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	62
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CILP1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.097407 (rank : 361)
Query Neighborhood Hits	181	Target Neighborhood Hits	266	Shared Neighborhood Hits	61
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.100812 (rank : 354)
Query Neighborhood Hits	181	Target Neighborhood Hits	282	Shared Neighborhood Hits	60
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP2_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.119680 (rank : 305)
Query Neighborhood Hits	181	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

COKA1_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.201873 (rank : 146)
Query Neighborhood Hits	181	Target Neighborhood Hits	403	Shared Neighborhood Hits	92
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CRLF2_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.079870 (rank : 406)
Query Neighborhood Hits	181	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CII9, Q9CRJ6, Q9JIE7, Q9JIQ7, Q9JJH8, Q9JMD5	Gene names	Crlf2, Crlm2, Tpte2, Tslpr
Domain Architecture
Description	Cytokine receptor-like factor 2 precursor (Type I cytokine receptor delta 1) (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

CSF1R_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.091723 (rank : 382)
Query Neighborhood Hits	181	Target Neighborhood Hits	943	Shared Neighborhood Hits	78
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSF1R_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.115560 (rank : 313)
Query Neighborhood Hits	181	Target Neighborhood Hits	983	Shared Neighborhood Hits	85
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSF2R_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.085267 (rank : 395)
Query Neighborhood Hits	181	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	P15509, O00207, Q14429, Q14430, Q14431, Q16564	Gene names	CSF2RA, CSF2R
Domain Architecture	No domain graphic available
Description	Granulocyte-macrophage colony-stimulating factor receptor alpha chain precursor (GM-CSF-R-alpha) (GMR) (CD116 antigen) (CDw116).

CSK_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.057600 (rank : 537)
Query Neighborhood Hits	181	Target Neighborhood Hits	1009	Shared Neighborhood Hits	31
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.056651 (rank : 547)
Query Neighborhood Hits	181	Target Neighborhood Hits	1009	Shared Neighborhood Hits	31
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CT075_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.076357 (rank : 414)
Query Neighborhood Hits	181	Target Neighborhood Hits	387	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

CT075_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.055136 (rank : 557)
Query Neighborhood Hits	181	Target Neighborhood Hits	358	Shared Neighborhood Hits	46
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

CXAR_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.104388 (rank : 341)
Query Neighborhood Hits	181	Target Neighborhood Hits	245	Shared Neighborhood Hits	44
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

CXAR_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.098305 (rank : 359)
Query Neighborhood Hits	181	Target Neighborhood Hits	250	Shared Neighborhood Hits	48
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

DDR1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.068321 (rank : 436)
Query Neighborhood Hits	181	Target Neighborhood Hits	819	Shared Neighborhood Hits	33
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.066998 (rank : 442)
Query Neighborhood Hits	181	Target Neighborhood Hits	818	Shared Neighborhood Hits	33
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.066691 (rank : 445)
Query Neighborhood Hits	181	Target Neighborhood Hits	818	Shared Neighborhood Hits	31
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.066205 (rank : 451)
Query Neighborhood Hits	181	Target Neighborhood Hits	813	Shared Neighborhood Hits	31
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

EGFR_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.065028 (rank : 460)
Query Neighborhood Hits	181	Target Neighborhood Hits	939	Shared Neighborhood Hits	32
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.065452 (rank : 457)
Query Neighborhood Hits	181	Target Neighborhood Hits	927	Shared Neighborhood Hits	34
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EMB_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.099796 (rank : 356)
Query Neighborhood Hits	181	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

EPHA1_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.119324 (rank : 306)
Query Neighborhood Hits	181	Target Neighborhood Hits	997	Shared Neighborhood Hits	78
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA1_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.123605 (rank : 300)
Query Neighborhood Hits	181	Target Neighborhood Hits	958	Shared Neighborhood Hits	87
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHAA_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.139673 (rank : 266)
Query Neighborhood Hits	181	Target Neighborhood Hits	960	Shared Neighborhood Hits	88
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHB6_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.173819 (rank : 202)
Query Neighborhood Hits	181	Target Neighborhood Hits	912	Shared Neighborhood Hits	106
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB6_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.171046 (rank : 212)
Query Neighborhood Hits	181	Target Neighborhood Hits	906	Shared Neighborhood Hits	99
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

ERBB2_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.066075 (rank : 452)
Query Neighborhood Hits	181	Target Neighborhood Hits	1073	Shared Neighborhood Hits	37
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.065471 (rank : 456)
Query Neighborhood Hits	181	Target Neighborhood Hits	918	Shared Neighborhood Hits	32
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.064496 (rank : 462)
Query Neighborhood Hits	181	Target Neighborhood Hits	918	Shared Neighborhood Hits	32
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.062797 (rank : 470)
Query Neighborhood Hits	181	Target Neighborhood Hits	898	Shared Neighborhood Hits	31
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.065749 (rank : 454)
Query Neighborhood Hits	181	Target Neighborhood Hits	910	Shared Neighborhood Hits	34
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ESAM_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.096839 (rank : 367)
Query Neighborhood Hits	181	Target Neighborhood Hits	251	Shared Neighborhood Hits	52
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ESAM_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.091366 (rank : 383)
Query Neighborhood Hits	181	Target Neighborhood Hits	222	Shared Neighborhood Hits	48
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

FAK1_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.066786 (rank : 443)
Query Neighborhood Hits	181	Target Neighborhood Hits	850	Shared Neighborhood Hits	31
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.066592 (rank : 448)
Query Neighborhood Hits	181	Target Neighborhood Hits	850	Shared Neighborhood Hits	31
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.067167 (rank : 441)
Query Neighborhood Hits	181	Target Neighborhood Hits	847	Shared Neighborhood Hits	31
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.066661 (rank : 446)
Query Neighborhood Hits	181	Target Neighborhood Hits	851	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FCERA_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.059779 (rank : 497)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	38
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

FCGR1_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.056507 (rank : 549)
Query Neighborhood Hits	181	Target Neighborhood Hits	145	Shared Neighborhood Hits	37
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

FCRL2_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.168997 (rank : 223)
Query Neighborhood Hits	181	Target Neighborhood Hits	251	Shared Neighborhood Hits	60
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

FCRL5_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.180373 (rank : 184)
Query Neighborhood Hits	181	Target Neighborhood Hits	267	Shared Neighborhood Hits	58
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

FER_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.060245 (rank : 490)
Query Neighborhood Hits	181	Target Neighborhood Hits	1278	Shared Neighborhood Hits	31
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FES_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.061606 (rank : 474)
Query Neighborhood Hits	181	Target Neighborhood Hits	978	Shared Neighborhood Hits	32
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.061676 (rank : 473)
Query Neighborhood Hits	181	Target Neighborhood Hits	980	Shared Neighborhood Hits	31
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FGFR1_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.132642 (rank : 285)
Query Neighborhood Hits	181	Target Neighborhood Hits	1069	Shared Neighborhood Hits	89
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR1_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.132420 (rank : 287)
Query Neighborhood Hits	181	Target Neighborhood Hits	1068	Shared Neighborhood Hits	89
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

FGFR2_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.132467 (rank : 286)
Query Neighborhood Hits	181	Target Neighborhood Hits	1062	Shared Neighborhood Hits	89
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

FGFR2_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.127885 (rank : 293)
Query Neighborhood Hits	181	Target Neighborhood Hits	1062	Shared Neighborhood Hits	89
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

FGFR3_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.131718 (rank : 290)
Query Neighborhood Hits	181	Target Neighborhood Hits	1042	Shared Neighborhood Hits	89
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

FGFR3_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.135098 (rank : 280)
Query Neighborhood Hits	181	Target Neighborhood Hits	1059	Shared Neighborhood Hits	91
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

FGFR4_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.136299 (rank : 276)
Query Neighborhood Hits	181	Target Neighborhood Hits	1037	Shared Neighborhood Hits	91
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

FGFR4_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.139371 (rank : 267)
Query Neighborhood Hits	181	Target Neighborhood Hits	1026	Shared Neighborhood Hits	92
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

FGRL1_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.251926 (rank : 108)
Query Neighborhood Hits	181	Target Neighborhood Hits	335	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

FGRL1_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.249959 (rank : 110)
Query Neighborhood Hits	181	Target Neighborhood Hits	325	Shared Neighborhood Hits	70
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

FGR_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.059389 (rank : 509)
Query Neighborhood Hits	181	Target Neighborhood Hits	1067	Shared Neighborhood Hits	31
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.059611 (rank : 501)
Query Neighborhood Hits	181	Target Neighborhood Hits	1069	Shared Neighborhood Hits	31
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FINC_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.361534 (rank : 73)
Query Neighborhood Hits	181	Target Neighborhood Hits	309	Shared Neighborhood Hits	124
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FLT3_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.065974 (rank : 453)
Query Neighborhood Hits	181	Target Neighborhood Hits	843	Shared Neighborhood Hits	45
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

FLT3_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.076207 (rank : 416)
Query Neighborhood Hits	181	Target Neighborhood Hits	847	Shared Neighborhood Hits	58
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

FRK_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.059100 (rank : 513)
Query Neighborhood Hits	181	Target Neighborhood Hits	1058	Shared Neighborhood Hits	31
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FSTL4_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.198425 (rank : 157)
Query Neighborhood Hits	181	Target Neighborhood Hits	344	Shared Neighborhood Hits	68
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL4_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.199319 (rank : 156)
Query Neighborhood Hits	181	Target Neighborhood Hits	333	Shared Neighborhood Hits	65
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL5_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.202510 (rank : 145)
Query Neighborhood Hits	181	Target Neighborhood Hits	347	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.198196 (rank : 158)
Query Neighborhood Hits	181	Target Neighborhood Hits	355	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FYN_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.058490 (rank : 525)
Query Neighborhood Hits	181	Target Neighborhood Hits	1078	Shared Neighborhood Hits	31
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.058921 (rank : 519)
Query Neighborhood Hits	181	Target Neighborhood Hits	1073	Shared Neighborhood Hits	31
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GPA33_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.123992 (rank : 299)
Query Neighborhood Hits	181	Target Neighborhood Hits	273	Shared Neighborhood Hits	50
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

GPA33_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.132363 (rank : 288)
Query Neighborhood Hits	181	Target Neighborhood Hits	294	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

GUC2C_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.054924 (rank : 559)
Query Neighborhood Hits	181	Target Neighborhood Hits	624	Shared Neighborhood Hits	27
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2F_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.054595 (rank : 561)
Query Neighborhood Hits	181	Target Neighborhood Hits	740	Shared Neighborhood Hits	31
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

HCFC1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.071958 (rank : 424)
Query Neighborhood Hits	181	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC2_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.135203 (rank : 279)
Query Neighborhood Hits	181	Target Neighborhood Hits	154	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HCFC2_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.205616 (rank : 141)
Query Neighborhood Hits	181	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

HCK_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.060673 (rank : 485)
Query Neighborhood Hits	181	Target Neighborhood Hits	1035	Shared Neighborhood Hits	32
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.060947 (rank : 483)
Query Neighborhood Hits	181	Target Neighborhood Hits	1029	Shared Neighborhood Hits	31
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HHLA2_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.074451 (rank : 420)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

HMCN1_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.190184 (rank : 170)
Query Neighborhood Hits	181	Target Neighborhood Hits	983	Shared Neighborhood Hits	85
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

I10R2_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.050379 (rank : 580)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	Q08334, Q9BUU4	Gene names	IL10RB, CRFB4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

I12R1_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.173141 (rank : 204)
Query Neighborhood Hits	181	Target Neighborhood Hits	78	Shared Neighborhood Hits	61
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

I12R1_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.127270 (rank : 294)
Query Neighborhood Hits	181	Target Neighborhood Hits	70	Shared Neighborhood Hits	47
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

IBP7_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.170672 (rank : 215)
Query Neighborhood Hits	181	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.168968 (rank : 224)
Query Neighborhood Hits	181	Target Neighborhood Hits	230	Shared Neighborhood Hits	63
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ICAM5_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.196832 (rank : 159)
Query Neighborhood Hits	181	Target Neighborhood Hits	276	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

ICAM5_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.203874 (rank : 144)
Query Neighborhood Hits	181	Target Neighborhood Hits	308	Shared Neighborhood Hits	64
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

IGF1R_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.097233 (rank : 363)
Query Neighborhood Hits	181	Target Neighborhood Hits	977	Shared Neighborhood Hits	80
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.096575 (rank : 368)
Query Neighborhood Hits	181	Target Neighborhood Hits	973	Shared Neighborhood Hits	81
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGS21_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.084096 (rank : 398)
Query Neighborhood Hits	181	Target Neighborhood Hits	123	Shared Neighborhood Hits	39
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS21_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.081639 (rank : 403)
Query Neighborhood Hits	181	Target Neighborhood Hits	118	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS4B_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.155596 (rank : 248)
Query Neighborhood Hits	181	Target Neighborhood Hits	305	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

IGS4B_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.159670 (rank : 237)
Query Neighborhood Hits	181	Target Neighborhood Hits	328	Shared Neighborhood Hits	63
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

IL12B_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.097237 (rank : 362)
Query Neighborhood Hits	181	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

IL12B_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.090859 (rank : 386)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

IL1R1_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.084297 (rank : 397)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

IL1R1_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.081495 (rank : 405)
Query Neighborhood Hits	181	Target Neighborhood Hits	142	Shared Neighborhood Hits	51
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

IL1R2_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.134895 (rank : 281)
Query Neighborhood Hits	181	Target Neighborhood Hits	153	Shared Neighborhood Hits	49
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

IL1R2_MOUSE
θ value	θ > 10 (rank : 316)	NC score	0.111881 (rank : 321)
Query Neighborhood Hits	181	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IL21R_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.153798 (rank : 254)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

IL2RB_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.104447 (rank : 340)
Query Neighborhood Hits	181	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL5RA_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.130543 (rank : 291)
Query Neighborhood Hits	181	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	Q01344, Q6ISX9	Gene names	IL5RA, IL5R
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen) (CDw125).

IL5RA_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.111141 (rank : 322)
Query Neighborhood Hits	181	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

IL9R_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.059560 (rank : 504)
Query Neighborhood Hits	181	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

IL9R_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.067223 (rank : 440)
Query Neighborhood Hits	181	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	Q01114	Gene names	Il9r
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

ILK1_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.053544 (rank : 567)
Query Neighborhood Hits	181	Target Neighborhood Hits	857	Shared Neighborhood Hits	31
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.053398 (rank : 568)
Query Neighborhood Hits	181	Target Neighborhood Hits	848	Shared Neighborhood Hits	31
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ILK_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.053724 (rank : 565)
Query Neighborhood Hits	181	Target Neighborhood Hits	858	Shared Neighborhood Hits	31
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ILRL1_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.073896 (rank : 422)
Query Neighborhood Hits	181	Target Neighborhood Hits	167	Shared Neighborhood Hits	44
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

ILRL2_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.061064 (rank : 482)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

ILRL2_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.082480 (rank : 402)
Query Neighborhood Hits	181	Target Neighborhood Hits	158	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

INAR1_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.057763 (rank : 534)
Query Neighborhood Hits	181	Target Neighborhood Hits	49	Shared Neighborhood Hits	21
SwissProt Accessions	P17181, Q53GW9, Q53H11, Q8WTZ2	Gene names	IFNAR1, IFNAR
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

INSRR_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.103888 (rank : 344)
Query Neighborhood Hits	181	Target Neighborhood Hits	950	Shared Neighborhood Hits	79
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.102474 (rank : 350)
Query Neighborhood Hits	181	Target Neighborhood Hits	961	Shared Neighborhood Hits	78
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSR_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.093826 (rank : 379)
Query Neighborhood Hits	181	Target Neighborhood Hits	963	Shared Neighborhood Hits	74
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.096898 (rank : 366)
Query Neighborhood Hits	181	Target Neighborhood Hits	968	Shared Neighborhood Hits	78
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

IRAK3_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.058110 (rank : 529)
Query Neighborhood Hits	181	Target Neighborhood Hits	644	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK3_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.058138 (rank : 528)
Query Neighborhood Hits	181	Target Neighborhood Hits	628	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRPL1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.097089 (rank : 364)
Query Neighborhood Hits	181	Target Neighborhood Hits	196	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

IRPL1_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.104270 (rank : 342)
Query Neighborhood Hits	181	Target Neighborhood Hits	186	Shared Neighborhood Hits	56
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

IRPL2_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.109162 (rank : 326)
Query Neighborhood Hits	181	Target Neighborhood Hits	194	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

IRPL2_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.108457 (rank : 329)
Query Neighborhood Hits	181	Target Neighborhood Hits	195	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

ITK_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.059749 (rank : 498)
Query Neighborhood Hits	181	Target Neighborhood Hits	1016	Shared Neighborhood Hits	31
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITK_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.059787 (rank : 496)
Query Neighborhood Hits	181	Target Neighborhood Hits	985	Shared Neighborhood Hits	31
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

JAK1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.056225 (rank : 553)
Query Neighborhood Hits	181	Target Neighborhood Hits	858	Shared Neighborhood Hits	32
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.056269 (rank : 552)
Query Neighborhood Hits	181	Target Neighborhood Hits	854	Shared Neighborhood Hits	31
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK2_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.054607 (rank : 560)
Query Neighborhood Hits	181	Target Neighborhood Hits	847	Shared Neighborhood Hits	31
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK2_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.053922 (rank : 562)
Query Neighborhood Hits	181	Target Neighborhood Hits	839	Shared Neighborhood Hits	31
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK3_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.053591 (rank : 566)
Query Neighborhood Hits	181	Target Neighborhood Hits	827	Shared Neighborhood Hits	31
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

JAK3_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.051561 (rank : 576)
Query Neighborhood Hits	181	Target Neighborhood Hits	821	Shared Neighborhood Hits	31
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

JAM1_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.185414 (rank : 176)
Query Neighborhood Hits	181	Target Neighborhood Hits	294	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

JAM1_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.178327 (rank : 192)
Query Neighborhood Hits	181	Target Neighborhood Hits	287	Shared Neighborhood Hits	62
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

JAM2_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.166913 (rank : 228)
Query Neighborhood Hits	181	Target Neighborhood Hits	304	Shared Neighborhood Hits	66
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM2_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.157446 (rank : 243)
Query Neighborhood Hits	181	Target Neighborhood Hits	292	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM3_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.190099 (rank : 171)
Query Neighborhood Hits	181	Target Neighborhood Hits	271	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAM3_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.188428 (rank : 172)
Query Neighborhood Hits	181	Target Neighborhood Hits	286	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAML1_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.074038 (rank : 421)
Query Neighborhood Hits	181	Target Neighborhood Hits	185	Shared Neighborhood Hits	33
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

KALM_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.218489 (rank : 123)
Query Neighborhood Hits	181	Target Neighborhood Hits	114	Shared Neighborhood Hits	68
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

KAZD1_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.186964 (rank : 175)
Query Neighborhood Hits	181	Target Neighborhood Hits	248	Shared Neighborhood Hits	60
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.193432 (rank : 163)
Query Neighborhood Hits	181	Target Neighborhood Hits	281	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KIRR1_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.182424 (rank : 180)
Query Neighborhood Hits	181	Target Neighborhood Hits	401	Shared Neighborhood Hits	68
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR1_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.180046 (rank : 186)
Query Neighborhood Hits	181	Target Neighborhood Hits	403	Shared Neighborhood Hits	66
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR2_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.200549 (rank : 153)
Query Neighborhood Hits	181	Target Neighborhood Hits	321	Shared Neighborhood Hits	65
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

KIRR2_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.200046 (rank : 155)
Query Neighborhood Hits	181	Target Neighborhood Hits	326	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

KIRR3_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.179612 (rank : 188)
Query Neighborhood Hits	181	Target Neighborhood Hits	302	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

KIRR3_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.175182 (rank : 200)
Query Neighborhood Hits	181	Target Neighborhood Hits	292	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

KIT_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.100164 (rank : 355)
Query Neighborhood Hits	181	Target Neighborhood Hits	953	Shared Neighborhood Hits	83
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.105733 (rank : 336)
Query Neighborhood Hits	181	Target Neighborhood Hits	949	Shared Neighborhood Hits	84
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KSYK_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.064386 (rank : 464)
Query Neighborhood Hits	181	Target Neighborhood Hits	901	Shared Neighborhood Hits	31
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.064226 (rank : 466)
Query Neighborhood Hits	181	Target Neighborhood Hits	944	Shared Neighborhood Hits	31
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAG3_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.053824 (rank : 563)
Query Neighborhood Hits	181	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

LCK_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.060265 (rank : 489)
Query Neighborhood Hits	181	Target Neighborhood Hits	987	Shared Neighborhood Hits	33
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.060383 (rank : 488)
Query Neighborhood Hits	181	Target Neighborhood Hits	981	Shared Neighborhood Hits	31
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LRC21_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.103031 (rank : 348)
Query Neighborhood Hits	181	Target Neighborhood Hits	456	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC21_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.109511 (rank : 325)
Query Neighborhood Hits	181	Target Neighborhood Hits	462	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC24_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.068645 (rank : 435)
Query Neighborhood Hits	181	Target Neighborhood Hits	404	Shared Neighborhood Hits	60
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC24_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.057530 (rank : 540)
Query Neighborhood Hits	181	Target Neighborhood Hits	387	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC4B_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.063184 (rank : 469)
Query Neighborhood Hits	181	Target Neighborhood Hits	479	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRC4B_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.064389 (rank : 463)
Query Neighborhood Hits	181	Target Neighborhood Hits	484	Shared Neighborhood Hits	58
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRFN2_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.106587 (rank : 333)
Query Neighborhood Hits	181	Target Neighborhood Hits	450	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN2_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.107994 (rank : 331)
Query Neighborhood Hits	181	Target Neighborhood Hits	450	Shared Neighborhood Hits	70
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN3_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.096296 (rank : 370)
Query Neighborhood Hits	181	Target Neighborhood Hits	444	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN3_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.101084 (rank : 353)
Query Neighborhood Hits	181	Target Neighborhood Hits	455	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN4_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.113674 (rank : 316)
Query Neighborhood Hits	181	Target Neighborhood Hits	462	Shared Neighborhood Hits	72
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN4_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.110483 (rank : 324)
Query Neighborhood Hits	181	Target Neighborhood Hits	442	Shared Neighborhood Hits	69
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN5_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.094090 (rank : 377)
Query Neighborhood Hits	181	Target Neighborhood Hits	464	Shared Neighborhood Hits	65
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRFN5_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.096487 (rank : 369)
Query Neighborhood Hits	181	Target Neighborhood Hits	472	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRIG1_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.170864 (rank : 213)
Query Neighborhood Hits	181	Target Neighborhood Hits	654	Shared Neighborhood Hits	69
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG1_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.168630 (rank : 225)
Query Neighborhood Hits	181	Target Neighborhood Hits	627	Shared Neighborhood Hits	68
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.172449 (rank : 207)
Query Neighborhood Hits	181	Target Neighborhood Hits	595	Shared Neighborhood Hits	70
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.171996 (rank : 208)
Query Neighborhood Hits	181	Target Neighborhood Hits	586	Shared Neighborhood Hits	70
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG3_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.164914 (rank : 232)
Query Neighborhood Hits	181	Target Neighborhood Hits	601	Shared Neighborhood Hits	71
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRIG3_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.165972 (rank : 230)
Query Neighborhood Hits	181	Target Neighborhood Hits	611	Shared Neighborhood Hits	70
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

LRRC4_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.057130 (rank : 545)
Query Neighborhood Hits	181	Target Neighborhood Hits	444	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

LRRN1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.089662 (rank : 388)
Query Neighborhood Hits	181	Target Neighborhood Hits	518	Shared Neighborhood Hits	70
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.085456 (rank : 393)
Query Neighborhood Hits	181	Target Neighborhood Hits	508	Shared Neighborhood Hits	70
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN3_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.083709 (rank : 401)
Query Neighborhood Hits	181	Target Neighborhood Hits	461	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN3_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.081623 (rank : 404)
Query Neighborhood Hits	181	Target Neighborhood Hits	455	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN5_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.075779 (rank : 418)
Query Neighborhood Hits	181	Target Neighborhood Hits	493	Shared Neighborhood Hits	65
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

LSAMP_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.221352 (rank : 120)
Query Neighborhood Hits	181	Target Neighborhood Hits	347	Shared Neighborhood Hits	68
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.222866 (rank : 119)
Query Neighborhood Hits	181	Target Neighborhood Hits	344	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

LTK_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.071491 (rank : 427)
Query Neighborhood Hits	181	Target Neighborhood Hits	774	Shared Neighborhood Hits	31
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.071877 (rank : 426)
Query Neighborhood Hits	181	Target Neighborhood Hits	770	Shared Neighborhood Hits	31
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LU_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.193237 (rank : 164)
Query Neighborhood Hits	181	Target Neighborhood Hits	283	Shared Neighborhood Hits	66
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

LYN_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.059449 (rank : 508)
Query Neighborhood Hits	181	Target Neighborhood Hits	1022	Shared Neighborhood Hits	31
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.059521 (rank : 506)
Query Neighborhood Hits	181	Target Neighborhood Hits	1023	Shared Neighborhood Hits	31
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MAG_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.205729 (rank : 140)
Query Neighborhood Hits	181	Target Neighborhood Hits	278	Shared Neighborhood Hits	67
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.205913 (rank : 139)
Query Neighborhood Hits	181	Target Neighborhood Hits	271	Shared Neighborhood Hits	67
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MALT1_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.214592 (rank : 129)
Query Neighborhood Hits	181	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

MAMC1_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.247993 (rank : 112)
Query Neighborhood Hits	181	Target Neighborhood Hits	357	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.248408 (rank : 111)
Query Neighborhood Hits	181	Target Neighborhood Hits	357	Shared Neighborhood Hits	71
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MATK_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.059897 (rank : 494)
Query Neighborhood Hits	181	Target Neighborhood Hits	954	Shared Neighborhood Hits	31
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.059575 (rank : 503)
Query Neighborhood Hits	181	Target Neighborhood Hits	952	Shared Neighborhood Hits	31
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MDGA1_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.244299 (rank : 114)
Query Neighborhood Hits	181	Target Neighborhood Hits	358	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MET_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.064217 (rank : 467)
Query Neighborhood Hits	181	Target Neighborhood Hits	831	Shared Neighborhood Hits	30
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.064382 (rank : 465)
Query Neighborhood Hits	181	Target Neighborhood Hits	844	Shared Neighborhood Hits	31
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MFA3L_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.173686 (rank : 203)
Query Neighborhood Hits	181	Target Neighborhood Hits	230	Shared Neighborhood Hits	61
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

MFA3L_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.151210 (rank : 257)
Query Neighborhood Hits	181	Target Neighborhood Hits	214	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

MLKL_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.052824 (rank : 572)
Query Neighborhood Hits	181	Target Neighborhood Hits	600	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MOX2R_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.085352 (rank : 394)
Query Neighborhood Hits	181	Target Neighborhood Hits	110	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

MUC18_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.200615 (rank : 152)
Query Neighborhood Hits	181	Target Neighborhood Hits	275	Shared Neighborhood Hits	64
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

MUC18_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.190379 (rank : 169)
Query Neighborhood Hits	181	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

MUSK_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.177357 (rank : 197)
Query Neighborhood Hits	181	Target Neighborhood Hits	1074	Shared Neighborhood Hits	89
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.178001 (rank : 194)
Query Neighborhood Hits	181	Target Neighborhood Hits	1057	Shared Neighborhood Hits	89
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MYBPH_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.211477 (rank : 131)
Query Neighborhood Hits	181	Target Neighborhood Hits	256	Shared Neighborhood Hits	84
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYBPH_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.223365 (rank : 118)
Query Neighborhood Hits	181	Target Neighborhood Hits	290	Shared Neighborhood Hits	91
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYOTI_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.256083 (rank : 106)
Query Neighborhood Hits	181	Target Neighborhood Hits	292	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

MYOTI_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.256553 (rank : 105)
Query Neighborhood Hits	181	Target Neighborhood Hits	297	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYPC2_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.278185 (rank : 95)
Query Neighborhood Hits	181	Target Neighborhood Hits	316	Shared Neighborhood Hits	104
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MYPC3_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.273535 (rank : 98)
Query Neighborhood Hits	181	Target Neighborhood Hits	318	Shared Neighborhood Hits	105
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MYPN_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.256888 (rank : 103)
Query Neighborhood Hits	181	Target Neighborhood Hits	418	Shared Neighborhood Hits	67
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

MYPN_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.251269 (rank : 109)
Query Neighborhood Hits	181	Target Neighborhood Hits	421	Shared Neighborhood Hits	66
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

NCAM2_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.298055 (rank : 87)
Query Neighborhood Hits	181	Target Neighborhood Hits	441	Shared Neighborhood Hits	112
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

NCAM2_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.303133 (rank : 86)
Query Neighborhood Hits	181	Target Neighborhood Hits	472	Shared Neighborhood Hits	115
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

NEGR1_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.221226 (rank : 121)
Query Neighborhood Hits	181	Target Neighborhood Hits	346	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

NEGR1_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.220095 (rank : 122)
Query Neighborhood Hits	181	Target Neighborhood Hits	349	Shared Neighborhood Hits	68
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

NGL1_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.061200 (rank : 479)
Query Neighborhood Hits	181	Target Neighborhood Hits	511	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.061279 (rank : 477)
Query Neighborhood Hits	181	Target Neighborhood Hits	512	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NPHN_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.283351 (rank : 93)
Query Neighborhood Hits	181	Target Neighborhood Hits	362	Shared Neighborhood Hits	96
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NPTN_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.204731 (rank : 143)
Query Neighborhood Hits	181	Target Neighborhood Hits	212	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NPTN_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.192663 (rank : 166)
Query Neighborhood Hits	181	Target Neighborhood Hits	216	Shared Neighborhood Hits	61
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NRG1_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.105772 (rank : 335)
Query Neighborhood Hits	181	Target Neighborhood Hits	285	Shared Neighborhood Hits	56
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.154005 (rank : 253)
Query Neighborhood Hits	181	Target Neighborhood Hits	419	Shared Neighborhood Hits	66
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.153111 (rank : 255)
Query Neighborhood Hits	181	Target Neighborhood Hits	392	Shared Neighborhood Hits	66
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NTRI_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.208849 (rank : 135)
Query Neighborhood Hits	181	Target Neighborhood Hits	344	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

NTRI_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.210940 (rank : 134)
Query Neighborhood Hits	181	Target Neighborhood Hits	342	Shared Neighborhood Hits	67
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

NTRK1_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.083960 (rank : 399)
Query Neighborhood Hits	181	Target Neighborhood Hits	1023	Shared Neighborhood Hits	75
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.116011 (rank : 312)
Query Neighborhood Hits	181	Target Neighborhood Hits	1081	Shared Neighborhood Hits	87
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.115284 (rank : 315)
Query Neighborhood Hits	181	Target Neighborhood Hits	1088	Shared Neighborhood Hits	87
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.113268 (rank : 317)
Query Neighborhood Hits	181	Target Neighborhood Hits	1115	Shared Neighborhood Hits	89
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

OBSCN_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.140353 (rank : 265)
Query Neighborhood Hits	181	Target Neighborhood Hits	1931	Shared Neighborhood Hits	117
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OBSL1_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.272933 (rank : 99)
Query Neighborhood Hits	181	Target Neighborhood Hits	354	Shared Neighborhood Hits	72
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

OPCM_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.215132 (rank : 127)
Query Neighborhood Hits	181	Target Neighborhood Hits	332	Shared Neighborhood Hits	70
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

PDL1_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.095252 (rank : 375)
Query Neighborhood Hits	181	Target Neighborhood Hits	195	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL1_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.069918 (rank : 433)
Query Neighborhood Hits	181	Target Neighborhood Hits	168	Shared Neighborhood Hits	42
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.069518 (rank : 434)
Query Neighborhood Hits	181	Target Neighborhood Hits	116	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PECA1_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.078882 (rank : 409)
Query Neighborhood Hits	181	Target Neighborhood Hits	178	Shared Neighborhood Hits	43
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

PECA1_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.065695 (rank : 455)
Query Neighborhood Hits	181	Target Neighborhood Hits	126	Shared Neighborhood Hits	32
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

PGBM_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.200213 (rank : 154)
Query Neighborhood Hits	181	Target Neighborhood Hits	1113	Shared Neighborhood Hits	98
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.195640 (rank : 161)
Query Neighborhood Hits	181	Target Neighborhood Hits	1073	Shared Neighborhood Hits	98
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGFRA_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.108122 (rank : 330)
Query Neighborhood Hits	181	Target Neighborhood Hits	980	Shared Neighborhood Hits	84
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.108536 (rank : 328)
Query Neighborhood Hits	181	Target Neighborhood Hits	975	Shared Neighborhood Hits	85
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRB_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.095771 (rank : 372)
Query Neighborhood Hits	181	Target Neighborhood Hits	962	Shared Neighborhood Hits	83
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRB_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.103528 (rank : 345)
Query Neighborhood Hits	181	Target Neighborhood Hits	960	Shared Neighborhood Hits	80
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRL_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.077331 (rank : 411)
Query Neighborhood Hits	181	Target Neighborhood Hits	115	Shared Neighborhood Hits	42
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

PGFRL_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.056409 (rank : 551)
Query Neighborhood Hits	181	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

PIGR_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.094032 (rank : 378)
Query Neighborhood Hits	181	Target Neighborhood Hits	164	Shared Neighborhood Hits	42
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

PIGR_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.091278 (rank : 385)
Query Neighborhood Hits	181	Target Neighborhood Hits	214	Shared Neighborhood Hits	44
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

PSG10_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.104243 (rank : 343)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

PSG11_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.101826 (rank : 352)
Query Neighborhood Hits	181	Target Neighborhood Hits	223	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

PSG1_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.105331 (rank : 339)
Query Neighborhood Hits	181	Target Neighborhood Hits	232	Shared Neighborhood Hits	61
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

PSG2_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.097879 (rank : 360)
Query Neighborhood Hits	181	Target Neighborhood Hits	229	Shared Neighborhood Hits	60
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

PSG3_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.115395 (rank : 314)
Query Neighborhood Hits	181	Target Neighborhood Hits	242	Shared Neighborhood Hits	63
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

PSG4_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.112166 (rank : 319)
Query Neighborhood Hits	181	Target Neighborhood Hits	243	Shared Neighborhood Hits	59
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

PSG5_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.086990 (rank : 391)
Query Neighborhood Hits	181	Target Neighborhood Hits	231	Shared Neighborhood Hits	58
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

PSG6_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.105858 (rank : 334)
Query Neighborhood Hits	181	Target Neighborhood Hits	231	Shared Neighborhood Hits	59
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

PSG7_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.105696 (rank : 337)
Query Neighborhood Hits	181	Target Neighborhood Hits	239	Shared Neighborhood Hits	60
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

PSG8_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.111998 (rank : 320)
Query Neighborhood Hits	181	Target Neighborhood Hits	239	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

PSG9_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.098553 (rank : 358)
Query Neighborhood Hits	181	Target Neighborhood Hits	221	Shared Neighborhood Hits	57
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

PTK6_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.056436 (rank : 550)
Query Neighborhood Hits	181	Target Neighborhood Hits	1020	Shared Neighborhood Hits	31
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.057595 (rank : 538)
Query Neighborhood Hits	181	Target Neighborhood Hits	1026	Shared Neighborhood Hits	31
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

PTK7_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.194092 (rank : 162)
Query Neighborhood Hits	181	Target Neighborhood Hits	1103	Shared Neighborhood Hits	94
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

PTN11_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.051477 (rank : 577)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.051473 (rank : 578)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.055508 (rank : 556)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.055080 (rank : 558)
Query Neighborhood Hits	181	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN18_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.056220 (rank : 554)
Query Neighborhood Hits	181	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.056553 (rank : 548)
Query Neighborhood Hits	181	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.057374 (rank : 542)
Query Neighborhood Hits	181	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.057281 (rank : 543)
Query Neighborhood Hits	181	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.057149 (rank : 544)
Query Neighborhood Hits	181	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.055520 (rank : 555)
Query Neighborhood Hits	181	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN2_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.058194 (rank : 527)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.057912 (rank : 532)
Query Neighborhood Hits	181	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN5_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.058773 (rank : 522)
Query Neighborhood Hits	181	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.058590 (rank : 524)
Query Neighborhood Hits	181	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.053053 (rank : 570)
Query Neighborhood Hits	181	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.053218 (rank : 569)
Query Neighborhood Hits	181	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.058878 (rank : 520)
Query Neighborhood Hits	181	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.058790 (rank : 521)
Query Neighborhood Hits	181	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.059616 (rank : 500)
Query Neighborhood Hits	181	Target Neighborhood Hits	79	Shared Neighborhood Hits	9
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.059803 (rank : 495)
Query Neighborhood Hits	181	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.057846 (rank : 533)
Query Neighborhood Hits	181	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.058039 (rank : 531)
Query Neighborhood Hits	181	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.076379 (rank : 413)
Query Neighborhood Hits	181	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.076296 (rank : 415)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	9
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRB_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.136978 (rank : 274)
Query Neighborhood Hits	181	Target Neighborhood Hits	242	Shared Neighborhood Hits	81
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRE_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.076202 (rank : 417)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.076440 (rank : 412)
Query Neighborhood Hits	181	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRG_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.085482 (rank : 392)
Query Neighborhood Hits	181	Target Neighborhood Hits	231	Shared Neighborhood Hits	42
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.084359 (rank : 396)
Query Neighborhood Hits	181	Target Neighborhood Hits	260	Shared Neighborhood Hits	40
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRK_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.175985 (rank : 198)
Query Neighborhood Hits	181	Target Neighborhood Hits	228	Shared Neighborhood Hits	92
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.178467 (rank : 191)
Query Neighborhood Hits	181	Target Neighborhood Hits	223	Shared Neighborhood Hits	91
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.215382 (rank : 126)
Query Neighborhood Hits	181	Target Neighborhood Hits	244	Shared Neighborhood Hits	105
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.213544 (rank : 130)
Query Neighborhood Hits	181	Target Neighborhood Hits	238	Shared Neighborhood Hits	107
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRN_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.058047 (rank : 530)
Query Neighborhood Hits	181	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.057072 (rank : 546)
Query Neighborhood Hits	181	Target Neighborhood Hits	240	Shared Neighborhood Hits	11
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.103250 (rank : 346)
Query Neighborhood Hits	181	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.057443 (rank : 541)
Query Neighborhood Hits	181	Target Neighborhood Hits	77	Shared Neighborhood Hits	9
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.057645 (rank : 536)
Query Neighborhood Hits	181	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRV_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.124453 (rank : 298)
Query Neighborhood Hits	181	Target Neighborhood Hits	179	Shared Neighborhood Hits	65
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.079358 (rank : 407)
Query Neighborhood Hits	181	Target Neighborhood Hits	255	Shared Neighborhood Hits	31
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PVRL1_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.061245 (rank : 478)
Query Neighborhood Hits	181	Target Neighborhood Hits	219	Shared Neighborhood Hits	36
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

PVRL1_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.059664 (rank : 499)
Query Neighborhood Hits	181	Target Neighborhood Hits	201	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

PVRL3_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.059251 (rank : 511)
Query Neighborhood Hits	181	Target Neighborhood Hits	204	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

PVRL3_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.070701 (rank : 429)
Query Neighborhood Hits	181	Target Neighborhood Hits	212	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

PVR_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.060818 (rank : 484)
Query Neighborhood Hits	181	Target Neighborhood Hits	195	Shared Neighborhood Hits	35
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

RAF1_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.051601 (rank : 575)
Query Neighborhood Hits	181	Target Neighborhood Hits	886	Shared Neighborhood Hits	31
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.051860 (rank : 573)
Query Neighborhood Hits	181	Target Neighborhood Hits	886	Shared Neighborhood Hits	31
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAGE_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.192960 (rank : 165)
Query Neighborhood Hits	181	Target Neighborhood Hits	269	Shared Neighborhood Hits	66
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RAGE_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.184423 (rank : 178)
Query Neighborhood Hits	181	Target Neighborhood Hits	295	Shared Neighborhood Hits	65
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RET_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.061066 (rank : 481)
Query Neighborhood Hits	181	Target Neighborhood Hits	873	Shared Neighborhood Hits	31
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.061464 (rank : 475)
Query Neighborhood Hits	181	Target Neighborhood Hits	884	Shared Neighborhood Hits	33
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RIMB2_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.091807 (rank : 381)
Query Neighborhood Hits	181	Target Neighborhood Hits	263	Shared Neighborhood Hits	46
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.089137 (rank : 389)
Query Neighborhood Hits	181	Target Neighborhood Hits	246	Shared Neighborhood Hits	43
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIPK3_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.050181 (rank : 582)
Query Neighborhood Hits	181	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

ROBO3_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.343188 (rank : 77)
Query Neighborhood Hits	181	Target Neighborhood Hits	524	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

RON_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.061373 (rank : 476)
Query Neighborhood Hits	181	Target Neighborhood Hits	842	Shared Neighborhood Hits	30
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.062778 (rank : 471)
Query Neighborhood Hits	181	Target Neighborhood Hits	836	Shared Neighborhood Hits	30
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.119163 (rank : 308)
Query Neighborhood Hits	181	Target Neighborhood Hits	1018	Shared Neighborhood Hits	89
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.117849 (rank : 309)
Query Neighborhood Hits	181	Target Neighborhood Hits	1025	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.122033 (rank : 302)
Query Neighborhood Hits	181	Target Neighborhood Hits	1014	Shared Neighborhood Hits	89
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.125511 (rank : 296)
Query Neighborhood Hits	181	Target Neighborhood Hits	1000	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

RYK_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.071916 (rank : 425)
Query Neighborhood Hits	181	Target Neighborhood Hits	701	Shared Neighborhood Hits	28
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 542)	NC score	0.070949 (rank : 428)
Query Neighborhood Hits	181	Target Neighborhood Hits	715	Shared Neighborhood Hits	28
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SIG10_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.157995 (rank : 240)
Query Neighborhood Hits	181	Target Neighborhood Hits	363	Shared Neighborhood Hits	63
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

SIG11_HUMAN
θ value	θ > 10 (rank : 544)	NC score	0.157355 (rank : 244)
Query Neighborhood Hits	181	Target Neighborhood Hits	273	Shared Neighborhood Hits	64
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

SIG12_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.077388 (rank : 410)
Query Neighborhood Hits	181	Target Neighborhood Hits	245	Shared Neighborhood Hits	60
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

SIGL5_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.095742 (rank : 373)
Query Neighborhood Hits	181	Target Neighborhood Hits	246	Shared Neighborhood Hits	54
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

SIGL5_MOUSE
θ value	θ > 10 (rank : 547)	NC score	0.127266 (rank : 295)
Query Neighborhood Hits	181	Target Neighborhood Hits	271	Shared Neighborhood Hits	60
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

SIGL6_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.075159 (rank : 419)
Query Neighborhood Hits	181	Target Neighborhood Hits	233	Shared Neighborhood Hits	57
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

SIGL8_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.088958 (rank : 390)
Query Neighborhood Hits	181	Target Neighborhood Hits	252	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

SN_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.195983 (rank : 160)
Query Neighborhood Hits	181	Target Neighborhood Hits	434	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

SN_MOUSE
θ value	θ > 10 (rank : 551)	NC score	0.205166 (rank : 142)
Query Neighborhood Hits	181	Target Neighborhood Hits	416	Shared Neighborhood Hits	74
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

SPEG_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.135838 (rank : 277)
Query Neighborhood Hits	181	Target Neighborhood Hits	1762	Shared Neighborhood Hits	103
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
θ value	θ > 10 (rank : 553)	NC score	0.137454 (rank : 270)
Query Neighborhood Hits	181	Target Neighborhood Hits	1959	Shared Neighborhood Hits	105
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRC_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.059043 (rank : 515)
Query Neighborhood Hits	181	Target Neighborhood Hits	1058	Shared Neighborhood Hits	31
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SRC_MOUSE
θ value	θ > 10 (rank : 555)	NC score	0.059544 (rank : 505)
Query Neighborhood Hits	181	Target Neighborhood Hits	1033	Shared Neighborhood Hits	31
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SRMS_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.061946 (rank : 472)
Query Neighborhood Hits	181	Target Neighborhood Hits	946	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 557)	NC score	0.060530 (rank : 487)
Query Neighborhood Hits	181	Target Neighborhood Hits	964	Shared Neighborhood Hits	31
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

STYK1_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.063360 (rank : 468)
Query Neighborhood Hits	181	Target Neighborhood Hits	786	Shared Neighborhood Hits	31
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

STYK1_MOUSE
θ value	θ > 10 (rank : 559)	NC score	0.064943 (rank : 461)
Query Neighborhood Hits	181	Target Neighborhood Hits	779	Shared Neighborhood Hits	32
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

TEC_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.059499 (rank : 507)
Query Neighborhood Hits	181	Target Neighborhood Hits	1006	Shared Neighborhood Hits	31
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 561)	NC score	0.059586 (rank : 502)
Query Neighborhood Hits	181	Target Neighborhood Hits	1006	Shared Neighborhood Hits	31
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TENA_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.154519 (rank : 250)
Query Neighborhood Hits	181	Target Neighborhood Hits	596	Shared Neighborhood Hits	109
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_MOUSE
θ value	θ > 10 (rank : 563)	NC score	0.227199 (rank : 116)
Query Neighborhood Hits	181	Target Neighborhood Hits	484	Shared Neighborhood Hits	111
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TIE1_HUMAN
θ value	θ > 10 (rank : 564)	NC score	0.133212 (rank : 284)
Query Neighborhood Hits	181	Target Neighborhood Hits	1241	Shared Neighborhood Hits	116
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.132072 (rank : 289)
Query Neighborhood Hits	181	Target Neighborhood Hits	1192	Shared Neighborhood Hits	114
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.137130 (rank : 271)
Query Neighborhood Hits	181	Target Neighborhood Hits	1204	Shared Neighborhood Hits	113
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TMIGD_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.206423 (rank : 138)
Query Neighborhood Hits	181	Target Neighborhood Hits	240	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TMIGD_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.201824 (rank : 147)
Query Neighborhood Hits	181	Target Neighborhood Hits	234	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TNK1_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.068008 (rank : 438)
Query Neighborhood Hits	181	Target Neighborhood Hits	815	Shared Neighborhood Hits	31
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TNK1_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.066607 (rank : 447)
Query Neighborhood Hits	181	Target Neighborhood Hits	806	Shared Neighborhood Hits	33
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TPOR_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.124964 (rank : 297)
Query Neighborhood Hits	181	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

TRIO_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.066777 (rank : 444)
Query Neighborhood Hits	181	Target Neighborhood Hits	1580	Shared Neighborhood Hits	88
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TXK_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.060576 (rank : 486)
Query Neighborhood Hits	181	Target Neighborhood Hits	971	Shared Neighborhood Hits	31
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.061095 (rank : 480)
Query Neighborhood Hits	181	Target Neighborhood Hits	980	Shared Neighborhood Hits	31
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TYK2_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.052929 (rank : 571)
Query Neighborhood Hits	181	Target Neighborhood Hits	841	Shared Neighborhood Hits	31
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TYK2_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.053770 (rank : 564)
Query Neighborhood Hits	181	Target Neighborhood Hits	850	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TYRO3_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.170003 (rank : 219)
Query Neighborhood Hits	181	Target Neighborhood Hits	995	Shared Neighborhood Hits	108
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

TYRO3_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.169595 (rank : 221)
Query Neighborhood Hits	181	Target Neighborhood Hits	1007	Shared Neighborhood Hits	107
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

UNC5A_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.111029 (rank : 323)
Query Neighborhood Hits	181	Target Neighborhood Hits	198	Shared Neighborhood Hits	58
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5A_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.096216 (rank : 371)
Query Neighborhood Hits	181	Target Neighborhood Hits	203	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.096927 (rank : 365)
Query Neighborhood Hits	181	Target Neighborhood Hits	225	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 582)	NC score	0.095627 (rank : 374)
Query Neighborhood Hits	181	Target Neighborhood Hits	226	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.102717 (rank : 349)
Query Neighborhood Hits	181	Target Neighborhood Hits	226	Shared Neighborhood Hits	60
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.103041 (rank : 347)
Query Neighborhood Hits	181	Target Neighborhood Hits	225	Shared Neighborhood Hits	62
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.112551 (rank : 318)
Query Neighborhood Hits	181	Target Neighborhood Hits	267	Shared Neighborhood Hits	63
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 586)	NC score	0.116336 (rank : 311)
Query Neighborhood Hits	181	Target Neighborhood Hits	268	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

VCAM1_HUMAN
θ value	θ > 10 (rank : 587)	NC score	0.201761 (rank : 148)
Query Neighborhood Hits	181	Target Neighborhood Hits	352	Shared Neighborhood Hits	62
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

VCAM1_MOUSE
θ value	θ > 10 (rank : 588)	NC score	0.207087 (rank : 136)
Query Neighborhood Hits	181	Target Neighborhood Hits	320	Shared Neighborhood Hits	63
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

VGFR1_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.146607 (rank : 261)
Query Neighborhood Hits	181	Target Neighborhood Hits	1109	Shared Neighborhood Hits	89
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

VGFR1_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.145676 (rank : 262)
Query Neighborhood Hits	181	Target Neighborhood Hits	1118	Shared Neighborhood Hits	90
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

VGFR2_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.138588 (rank : 269)
Query Neighborhood Hits	181	Target Neighborhood Hits	1103	Shared Neighborhood Hits	89
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

VGFR2_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.137058 (rank : 272)
Query Neighborhood Hits	181	Target Neighborhood Hits	1089	Shared Neighborhood Hits	89
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

VGFR3_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.119276 (rank : 307)
Query Neighborhood Hits	181	Target Neighborhood Hits	1037	Shared Neighborhood Hits	91
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VGFR3_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.116838 (rank : 310)
Query Neighborhood Hits	181	Target Neighborhood Hits	1056	Shared Neighborhood Hits	89
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VSIG2_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.177415 (rank : 196)
Query Neighborhood Hits	181	Target Neighborhood Hits	321	Shared Neighborhood Hits	66
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG2_MOUSE
θ value	θ > 10 (rank : 596)	NC score	0.169812 (rank : 220)
Query Neighborhood Hits	181	Target Neighborhood Hits	316	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG4_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.135465 (rank : 278)
Query Neighborhood Hits	181	Target Neighborhood Hits	236	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

YES_HUMAN
θ value	θ > 10 (rank : 598)	NC score	0.060131 (rank : 491)
Query Neighborhood Hits	181	Target Neighborhood Hits	1059	Shared Neighborhood Hits	32
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	θ > 10 (rank : 599)	NC score	0.060118 (rank : 492)
Query Neighborhood Hits	181	Target Neighborhood Hits	1052	Shared Neighborhood Hits	31
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ZAP70_HUMAN
θ value	θ > 10 (rank : 600)	NC score	0.066492 (rank : 450)
Query Neighborhood Hits	181	Target Neighborhood Hits	893	Shared Neighborhood Hits	31
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.066537 (rank : 449)
Query Neighborhood Hits	181	Target Neighborhood Hits	905	Shared Neighborhood Hits	31
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

Hits sorted by NC score

IL6RB_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	181
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
NC score	0.969500 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	181	Target Neighborhood Hits	168	Shared Neighborhood Hits	147
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

CSF3R_HUMAN
NC score	0.810442 (rank : 3)	θ value	8.26713e-62 (rank : 3)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	97
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

I12R2_HUMAN
NC score	0.803324 (rank : 4)	θ value	5.21438e-40 (rank : 6)
Query Neighborhood Hits	181	Target Neighborhood Hits	163	Shared Neighborhood Hits	111
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
NC score	0.801040 (rank : 5)	θ value	1.51715e-39 (rank : 7)
Query Neighborhood Hits	181	Target Neighborhood Hits	143	Shared Neighborhood Hits	112
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

LIFR_HUMAN
NC score	0.781588 (rank : 6)	θ value	1.12253e-42 (rank : 5)
Query Neighborhood Hits	181	Target Neighborhood Hits	130	Shared Neighborhood Hits	104
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

CSF3R_MOUSE
NC score	0.777664 (rank : 7)	θ value	6.35935e-46 (rank : 4)
Query Neighborhood Hits	181	Target Neighborhood Hits	104	Shared Neighborhood Hits	81
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

LIFR_MOUSE
NC score	0.757222 (rank : 8)	θ value	4.568e-36 (rank : 8)
Query Neighborhood Hits	181	Target Neighborhood Hits	127	Shared Neighborhood Hits	94
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

CRLF1_MOUSE
NC score	0.707750 (rank : 9)	θ value	2.05525e-28 (rank : 9)
Query Neighborhood Hits	181	Target Neighborhood Hits	116	Shared Neighborhood Hits	96
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CRLF1_HUMAN
NC score	0.704479 (rank : 10)	θ value	1.02001e-27 (rank : 10)
Query Neighborhood Hits	181	Target Neighborhood Hits	122	Shared Neighborhood Hits	98
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

LEPR_MOUSE
NC score	0.601472 (rank : 11)	θ value	4.28545e-26 (rank : 11)
Query Neighborhood Hits	181	Target Neighborhood Hits	109	Shared Neighborhood Hits	77
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

LEPR_HUMAN
NC score	0.577918 (rank : 12)	θ value	4.9032e-22 (rank : 12)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	79
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

I27RA_HUMAN
NC score	0.524973 (rank : 13)	θ value	9.90251e-15 (rank : 15)
Query Neighborhood Hits	181	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

PRLR_MOUSE
NC score	0.523898 (rank : 14)	θ value	1.24977e-17 (rank : 13)
Query Neighborhood Hits	181	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

PRLR_HUMAN
NC score	0.514468 (rank : 15)	θ value	7.09661e-13 (rank : 22)
Query Neighborhood Hits	181	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

I27RA_MOUSE
NC score	0.509799 (rank : 16)	θ value	1.86753e-13 (rank : 17)
Query Neighborhood Hits	181	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

SDK2_MOUSE
NC score	0.495890 (rank : 17)	θ value	1.86753e-13 (rank : 18)
Query Neighborhood Hits	181	Target Neighborhood Hits	480	Shared Neighborhood Hits	135
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_MOUSE
NC score	0.494431 (rank : 18)	θ value	2.69671e-12 (rank : 25)
Query Neighborhood Hits	181	Target Neighborhood Hits	495	Shared Neighborhood Hits	135
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
NC score	0.493457 (rank : 19)	θ value	7.09661e-13 (rank : 24)
Query Neighborhood Hits	181	Target Neighborhood Hits	495	Shared Neighborhood Hits	138
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_HUMAN
NC score	0.490192 (rank : 20)	θ value	7.09661e-13 (rank : 23)
Query Neighborhood Hits	181	Target Neighborhood Hits	511	Shared Neighborhood Hits	136
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

NRCAM_HUMAN
NC score	0.472570 (rank : 21)	θ value	7.09661e-13 (rank : 20)
Query Neighborhood Hits	181	Target Neighborhood Hits	439	Shared Neighborhood Hits	127
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NEO1_MOUSE
NC score	0.468349 (rank : 22)	θ value	6.87365e-08 (rank : 43)
Query Neighborhood Hits	181	Target Neighborhood Hits	523	Shared Neighborhood Hits	136
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NEO1_HUMAN
NC score	0.467923 (rank : 23)	θ value	6.87365e-08 (rank : 42)
Query Neighborhood Hits	181	Target Neighborhood Hits	530	Shared Neighborhood Hits	136
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NRCAM_MOUSE
NC score	0.461318 (rank : 24)	θ value	7.09661e-13 (rank : 21)
Query Neighborhood Hits	181	Target Neighborhood Hits	432	Shared Neighborhood Hits	123
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

FNDC3_MOUSE
NC score	0.453224 (rank : 25)	θ value	0.0736092 (rank : 125)
Query Neighborhood Hits	181	Target Neighborhood Hits	207	Shared Neighborhood Hits	124
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_HUMAN
NC score	0.453110 (rank : 26)	θ value	0.0961366 (rank : 129)
Query Neighborhood Hits	181	Target Neighborhood Hits	196	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

CNTN3_HUMAN
NC score	0.448721 (rank : 27)	θ value	1.80886e-08 (rank : 36)
Query Neighborhood Hits	181	Target Neighborhood Hits	455	Shared Neighborhood Hits	126
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN3_MOUSE
NC score	0.447243 (rank : 28)	θ value	2.52405e-10 (rank : 28)
Query Neighborhood Hits	181	Target Neighborhood Hits	447	Shared Neighborhood Hits	127
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

DSCL1_HUMAN
NC score	0.445769 (rank : 29)	θ value	4.45536e-07 (rank : 47)
Query Neighborhood Hits	181	Target Neighborhood Hits	589	Shared Neighborhood Hits	132
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

L1CAM_HUMAN
NC score	0.445217 (rank : 30)	θ value	3.19293e-05 (rank : 66)
Query Neighborhood Hits	181	Target Neighborhood Hits	457	Shared Neighborhood Hits	128
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CNTFR_MOUSE
NC score	0.445075 (rank : 31)	θ value	1.74796e-11 (rank : 26)
Query Neighborhood Hits	181	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	O88507, Q80T01	Gene names	Cntfr
Domain Architecture	No domain graphic available
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

CNTFR_HUMAN
NC score	0.441930 (rank : 32)	θ value	3.89403e-11 (rank : 27)
Query Neighborhood Hits	181	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	P26992	Gene names	CNTFR
Domain Architecture
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

MYOM1_HUMAN
NC score	0.441837 (rank : 33)	θ value	1.99992e-07 (rank : 44)
Query Neighborhood Hits	181	Target Neighborhood Hits	405	Shared Neighborhood Hits	122
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

L1CAM_MOUSE
NC score	0.441356 (rank : 34)	θ value	0.00102713 (rank : 93)
Query Neighborhood Hits	181	Target Neighborhood Hits	457	Shared Neighborhood Hits	130
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

DSCAM_HUMAN
NC score	0.439636 (rank : 35)	θ value	1.38499e-08 (rank : 33)
Query Neighborhood Hits	181	Target Neighborhood Hits	524	Shared Neighborhood Hits	131
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DCC_HUMAN
NC score	0.438954 (rank : 36)	θ value	7.59969e-07 (rank : 52)
Query Neighborhood Hits	181	Target Neighborhood Hits	583	Shared Neighborhood Hits	131
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

I11RB_MOUSE
NC score	0.435183 (rank : 37)	θ value	5.81887e-07 (rank : 51)
Query Neighborhood Hits	181	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

IL6RA_MOUSE
NC score	0.434478 (rank : 38)	θ value	2.61198e-07 (rank : 45)
Query Neighborhood Hits	181	Target Neighborhood Hits	104	Shared Neighborhood Hits	57
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

CHL1_HUMAN
NC score	0.433142 (rank : 39)	θ value	0.000461057 (rank : 85)
Query Neighborhood Hits	181	Target Neighborhood Hits	413	Shared Neighborhood Hits	121
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

DCC_MOUSE
NC score	0.429978 (rank : 40)	θ value	1.69304e-06 (rank : 56)
Query Neighborhood Hits	181	Target Neighborhood Hits	896	Shared Neighborhood Hits	133
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

I11RA_MOUSE
NC score	0.426521 (rank : 41)	θ value	9.92553e-07 (rank : 54)
Query Neighborhood Hits	181	Target Neighborhood Hits	95	Shared Neighborhood Hits	56
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

I11RA_HUMAN
NC score	0.425151 (rank : 42)	θ value	4.45536e-07 (rank : 48)
Query Neighborhood Hits	181	Target Neighborhood Hits	138	Shared Neighborhood Hits	59
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

IL6RA_HUMAN
NC score	0.424747 (rank : 43)	θ value	3.08544e-08 (rank : 38)
Query Neighborhood Hits	181	Target Neighborhood Hits	96	Shared Neighborhood Hits	48
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

CNTN5_HUMAN
NC score	0.421451 (rank : 44)	θ value	2.79066e-09 (rank : 31)
Query Neighborhood Hits	181	Target Neighborhood Hits	446	Shared Neighborhood Hits	124
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

NFASC_HUMAN
NC score	0.420418 (rank : 45)	θ value	0.000461057 (rank : 86)
Query Neighborhood Hits	181	Target Neighborhood Hits	497	Shared Neighborhood Hits	124
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

CHL1_MOUSE
NC score	0.419623 (rank : 46)	θ value	0.47712 (rank : 144)
Query Neighborhood Hits	181	Target Neighborhood Hits	402	Shared Neighborhood Hits	115
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CNTN1_HUMAN
NC score	0.417412 (rank : 47)	θ value	9.92553e-07 (rank : 53)
Query Neighborhood Hits	181	Target Neighborhood Hits	431	Shared Neighborhood Hits	118
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CNTN5_MOUSE
NC score	0.416726 (rank : 48)	θ value	5.81887e-07 (rank : 49)
Query Neighborhood Hits	181	Target Neighborhood Hits	434	Shared Neighborhood Hits	120
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CNTN4_HUMAN
NC score	0.415989 (rank : 49)	θ value	2.79066e-09 (rank : 30)
Query Neighborhood Hits	181	Target Neighborhood Hits	449	Shared Neighborhood Hits	116
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN4_MOUSE
NC score	0.415402 (rank : 50)	θ value	2.36244e-08 (rank : 37)
Query Neighborhood Hits	181	Target Neighborhood Hits	445	Shared Neighborhood Hits	115
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN2_HUMAN
NC score	0.415130 (rank : 51)	θ value	0.00509761 (rank : 103)
Query Neighborhood Hits	181	Target Neighborhood Hits	440	Shared Neighborhood Hits	120
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN1_MOUSE
NC score	0.413759 (rank : 52)	θ value	1.09739e-05 (rank : 60)
Query Neighborhood Hits	181	Target Neighborhood Hits	422	Shared Neighborhood Hits	115
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN6_HUMAN
NC score	0.412934 (rank : 53)	θ value	1.09739e-05 (rank : 61)
Query Neighborhood Hits	181	Target Neighborhood Hits	422	Shared Neighborhood Hits	113
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

PTPRD_HUMAN
NC score	0.411910 (rank : 54)	θ value	5.8054e-15 (rank : 14)
Query Neighborhood Hits	181	Target Neighborhood Hits	485	Shared Neighborhood Hits	137
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
NC score	0.409809 (rank : 55)	θ value	2.88119e-14 (rank : 16)
Query Neighborhood Hits	181	Target Neighborhood Hits	491	Shared Neighborhood Hits	136
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

MYOM2_HUMAN
NC score	0.409576 (rank : 56)	θ value	5.44631e-05 (rank : 74)
Query Neighborhood Hits	181	Target Neighborhood Hits	341	Shared Neighborhood Hits	115
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

MYOM1_MOUSE
NC score	0.409151 (rank : 57)	θ value	0.000786445 (rank : 91)
Query Neighborhood Hits	181	Target Neighborhood Hits	415	Shared Neighborhood Hits	127
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

CNTN6_MOUSE
NC score	0.407576 (rank : 58)	θ value	0.000270298 (rank : 81)
Query Neighborhood Hits	181	Target Neighborhood Hits	429	Shared Neighborhood Hits	117
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

NFASC_MOUSE
NC score	0.406220 (rank : 59)	θ value	1.09739e-05 (rank : 62)
Query Neighborhood Hits	181	Target Neighborhood Hits	475	Shared Neighborhood Hits	122
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

CNTN2_MOUSE
NC score	0.403469 (rank : 60)	θ value	0.0252991 (rank : 119)
Query Neighborhood Hits	181	Target Neighborhood Hits	450	Shared Neighborhood Hits	120
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

PTPRF_HUMAN
NC score	0.396295 (rank : 61)	θ value	3.18553e-13 (rank : 19)
Query Neighborhood Hits	181	Target Neighborhood Hits	489	Shared Neighborhood Hits	130
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

IL27B_HUMAN
NC score	0.393168 (rank : 62)	θ value	0.000270298 (rank : 82)
Query Neighborhood Hits	181	Target Neighborhood Hits	80	Shared Neighborhood Hits	66
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

PTPRS_HUMAN
NC score	0.380338 (rank : 63)	θ value	5.26297e-08 (rank : 40)
Query Neighborhood Hits	181	Target Neighborhood Hits	472	Shared Neighborhood Hits	128
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

ROBO2_MOUSE
NC score	0.379162 (rank : 64)	θ value	6.43352e-06 (rank : 58)
Query Neighborhood Hits	181	Target Neighborhood Hits	504	Shared Neighborhood Hits	124
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO2_HUMAN
NC score	0.375979 (rank : 65)	θ value	3.19293e-05 (rank : 67)
Query Neighborhood Hits	181	Target Neighborhood Hits	479	Shared Neighborhood Hits	123
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

CDON_HUMAN
NC score	0.367201 (rank : 66)	θ value	0.000786445 (rank : 87)
Query Neighborhood Hits	181	Target Neighborhood Hits	412	Shared Neighborhood Hits	104
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

PUNC_HUMAN
NC score	0.367175 (rank : 67)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	181	Target Neighborhood Hits	449	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

IL27B_MOUSE
NC score	0.366132 (rank : 68)	θ value	4.1701e-05 (rank : 69)
Query Neighborhood Hits	181	Target Neighborhood Hits	55	Shared Neighborhood Hits	46
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

ROBO1_MOUSE
NC score	0.366071 (rank : 69)	θ value	9.29e-05 (rank : 77)
Query Neighborhood Hits	181	Target Neighborhood Hits	559	Shared Neighborhood Hits	125
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

PUNC_MOUSE
NC score	0.364973 (rank : 70)	θ value	0.0330416 (rank : 124)
Query Neighborhood Hits	181	Target Neighborhood Hits	501	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO1_HUMAN
NC score	0.363971 (rank : 71)	θ value	2.44474e-05 (rank : 64)
Query Neighborhood Hits	181	Target Neighborhood Hits	529	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

CDON_MOUSE
NC score	0.362749 (rank : 72)	θ value	0.00228821 (rank : 99)
Query Neighborhood Hits	181	Target Neighborhood Hits	410	Shared Neighborhood Hits	105
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

FINC_MOUSE
NC score	0.361534 (rank : 73)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	181	Target Neighborhood Hits	309	Shared Neighborhood Hits	124
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

ROBO3_HUMAN
NC score	0.354181 (rank : 74)	θ value	0.0961366 (rank : 130)
Query Neighborhood Hits	181	Target Neighborhood Hits	570	Shared Neighborhood Hits	119
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

FINC_HUMAN
NC score	0.349520 (rank : 75)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	181	Target Neighborhood Hits	302	Shared Neighborhood Hits	128
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

BOC_HUMAN
NC score	0.343757 (rank : 76)	θ value	0.47712 (rank : 143)
Query Neighborhood Hits	181	Target Neighborhood Hits	543	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

ROBO3_MOUSE
NC score	0.343188 (rank : 77)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	181	Target Neighborhood Hits	524	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

BOC_MOUSE
NC score	0.342889 (rank : 78)	θ value	1.06291 (rank : 151)
Query Neighborhood Hits	181	Target Neighborhood Hits	433	Shared Neighborhood Hits	105
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

USH2A_HUMAN
NC score	0.334045 (rank : 79)	θ value	1.06045e-08 (rank : 32)
Query Neighborhood Hits	181	Target Neighborhood Hits	600	Shared Neighborhood Hits	128
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

COCA1_MOUSE
NC score	0.329632 (rank : 80)	θ value	2.44474e-05 (rank : 63)
Query Neighborhood Hits	181	Target Neighborhood Hits	467	Shared Neighborhood Hits	131
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ROBO4_HUMAN
NC score	0.329033 (rank : 81)	θ value	0.813845 (rank : 150)
Query Neighborhood Hits	181	Target Neighborhood Hits	364	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

COCA1_HUMAN
NC score	0.326835 (rank : 82)	θ value	2.21117e-06 (rank : 57)
Query Neighborhood Hits	181	Target Neighborhood Hits	458	Shared Neighborhood Hits	124
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

USH2A_MOUSE
NC score	0.322645 (rank : 83)	θ value	4.0297e-08 (rank : 39)
Query Neighborhood Hits	181	Target Neighborhood Hits	626	Shared Neighborhood Hits	128
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

ROBO4_MOUSE
NC score	0.316325 (rank : 84)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	181	Target Neighborhood Hits	358	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

I13R2_HUMAN
NC score	0.314129 (rank : 85)	θ value	0.000786445 (rank : 90)
Query Neighborhood Hits	181	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

NCAM2_MOUSE
NC score	0.303133 (rank : 86)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	181	Target Neighborhood Hits	472	Shared Neighborhood Hits	115
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

NCAM2_HUMAN
NC score	0.298055 (rank : 87)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	181	Target Neighborhood Hits	441	Shared Neighborhood Hits	112
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

NCA11_HUMAN
NC score	0.294558 (rank : 88)	θ value	0.0193708 (rank : 116)
Query Neighborhood Hits	181	Target Neighborhood Hits	443	Shared Neighborhood Hits	102
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NPHN_MOUSE
NC score	0.293920 (rank : 89)	θ value	0.163984 (rank : 136)
Query Neighborhood Hits	181	Target Neighborhood Hits	370	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NCA11_MOUSE
NC score	0.288114 (rank : 90)	θ value	0.0736092 (rank : 126)
Query Neighborhood Hits	181	Target Neighborhood Hits	661	Shared Neighborhood Hits	102
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCA12_HUMAN
NC score	0.286070 (rank : 91)	θ value	0.0193708 (rank : 117)
Query Neighborhood Hits	181	Target Neighborhood Hits	437	Shared Neighborhood Hits	97
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

MYPC2_MOUSE
NC score	0.283614 (rank : 92)	θ value	0.21417 (rank : 140)
Query Neighborhood Hits	181	Target Neighborhood Hits	297	Shared Neighborhood Hits	95
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NPHN_HUMAN
NC score	0.283351 (rank : 93)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	181	Target Neighborhood Hits	362	Shared Neighborhood Hits	96
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NCA12_MOUSE
NC score	0.282112 (rank : 94)	θ value	1.38821 (rank : 155)
Query Neighborhood Hits	181	Target Neighborhood Hits	399	Shared Neighborhood Hits	92
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

MYPC2_HUMAN
NC score	0.278185 (rank : 95)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	181	Target Neighborhood Hits	316	Shared Neighborhood Hits	104
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

MYPC3_MOUSE
NC score	0.275832 (rank : 96)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	106
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

I13R1_HUMAN
NC score	0.274481 (rank : 97)	θ value	6.87365e-08 (rank : 41)
Query Neighborhood Hits	181	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

MYPC3_HUMAN
NC score	0.273535 (rank : 98)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	181	Target Neighborhood Hits	318	Shared Neighborhood Hits	105
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

OBSL1_HUMAN
NC score	0.272933 (rank : 99)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	181	Target Neighborhood Hits	354	Shared Neighborhood Hits	72
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

I13R1_MOUSE
NC score	0.267985 (rank : 100)	θ value	9.29e-05 (rank : 76)
Query Neighborhood Hits	181	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

COEA1_MOUSE
NC score	0.265467 (rank : 101)	θ value	8.40245e-06 (rank : 59)
Query Neighborhood Hits	181	Target Neighborhood Hits	402	Shared Neighborhood Hits	88
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

ITB4_HUMAN
NC score	0.264867 (rank : 102)	θ value	0.125558 (rank : 132)
Query Neighborhood Hits	181	Target Neighborhood Hits	458	Shared Neighborhood Hits	117
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

MYPN_HUMAN
NC score	0.256888 (rank : 103)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	181	Target Neighborhood Hits	418	Shared Neighborhood Hits	67
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

MYPC1_HUMAN
NC score	0.256713 (rank : 104)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	181	Target Neighborhood Hits	303	Shared Neighborhood Hits	91
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

MYOTI_MOUSE
NC score	0.256553 (rank : 105)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	181	Target Neighborhood Hits	297	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYOTI_HUMAN
NC score	0.256083 (rank : 106)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	181	Target Neighborhood Hits	292	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

IL7RA_HUMAN
NC score	0.252880 (rank : 107)	θ value	5.44631e-05 (rank : 73)
Query Neighborhood Hits	181	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	P16871, Q6SV45, Q9UPC1	Gene names	IL7R
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen) (CDw127).

FGRL1_HUMAN
NC score	0.251926 (rank : 108)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	181	Target Neighborhood Hits	335	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

MYPN_MOUSE
NC score	0.251269 (rank : 109)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	181	Target Neighborhood Hits	421	Shared Neighborhood Hits	66
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

FGRL1_MOUSE
NC score	0.249959 (rank : 110)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	181	Target Neighborhood Hits	325	Shared Neighborhood Hits	70
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

MAMC1_MOUSE
NC score	0.248408 (rank : 111)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	181	Target Neighborhood Hits	357	Shared Neighborhood Hits	71
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_HUMAN
NC score	0.247993 (rank : 112)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	181	Target Neighborhood Hits	357	Shared Neighborhood Hits	71
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

TITIN_HUMAN
NC score	0.246518 (rank : 113)	θ value	2.13673e-09 (rank : 29)
Query Neighborhood Hits	181	Target Neighborhood Hits	2923	Shared Neighborhood Hits	152
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MDGA1_HUMAN
NC score	0.244299 (rank : 114)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	181	Target Neighborhood Hits	358	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

COEA1_HUMAN
NC score	0.242593 (rank : 115)	θ value	4.45536e-07 (rank : 46)
Query Neighborhood Hits	181	Target Neighborhood Hits	427	Shared Neighborhood Hits	103
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

TENN_MOUSE
NC score	0.227199 (rank : 116)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	181	Target Neighborhood Hits	484	Shared Neighborhood Hits	111
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
NC score	0.223538 (rank : 117)	θ value	0.62314 (rank : 149)
Query Neighborhood Hits	181	Target Neighborhood Hits	526	Shared Neighborhood Hits	112
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

MYBPH_MOUSE
NC score	0.223365 (rank : 118)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	181	Target Neighborhood Hits	290	Shared Neighborhood Hits	91
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

LSAMP_MOUSE
NC score	0.222866 (rank : 119)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	181	Target Neighborhood Hits	344	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_HUMAN
NC score	0.221352 (rank : 120)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	181	Target Neighborhood Hits	347	Shared Neighborhood Hits	68
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

NEGR1_HUMAN
NC score	0.221226 (rank : 121)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	181	Target Neighborhood Hits	346	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

NEGR1_MOUSE
NC score	0.220095 (rank : 122)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	181	Target Neighborhood Hits	349	Shared Neighborhood Hits	68
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

KALM_HUMAN
NC score	0.218489 (rank : 123)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	181	Target Neighborhood Hits	114	Shared Neighborhood Hits	68
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

IL7RA_MOUSE
NC score	0.217395 (rank : 124)	θ value	3.19293e-05 (rank : 65)
Query Neighborhood Hits	181	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

TENR_MOUSE
NC score	0.216425 (rank : 125)	θ value	1.38821 (rank : 156)
Query Neighborhood Hits	181	Target Neighborhood Hits	531	Shared Neighborhood Hits	112
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

PTPRM_HUMAN
NC score	0.215382 (rank : 126)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	181	Target Neighborhood Hits	244	Shared Neighborhood Hits	105
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

OPCM_HUMAN
NC score	0.215132 (rank : 127)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	181	Target Neighborhood Hits	332	Shared Neighborhood Hits	70
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

CO7A1_HUMAN
NC score	0.214676 (rank : 128)	θ value	0.0252991 (rank : 120)
Query Neighborhood Hits	181	Target Neighborhood Hits	807	Shared Neighborhood Hits	113
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

MALT1_HUMAN
NC score	0.214592 (rank : 129)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	181	Target Neighborhood Hits	236	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

PTPRM_MOUSE
NC score	0.213544 (rank : 130)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	181	Target Neighborhood Hits	238	Shared Neighborhood Hits	107
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

MYBPH_HUMAN
NC score	0.211477 (rank : 131)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	181	Target Neighborhood Hits	256	Shared Neighborhood Hits	84
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

PTPRT_MOUSE
NC score	0.211237 (rank : 132)	θ value	0.00869519 (rank : 112)
Query Neighborhood Hits	181	Target Neighborhood Hits	219	Shared Neighborhood Hits	100
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.211187 (rank : 133)	θ value	0.00869519 (rank : 111)
Query Neighborhood Hits	181	Target Neighborhood Hits	217	Shared Neighborhood Hits	100
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

NTRI_MOUSE
NC score	0.210940 (rank : 134)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	181	Target Neighborhood Hits	342	Shared Neighborhood Hits	67
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

NTRI_HUMAN
NC score	0.208849 (rank : 135)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	181	Target Neighborhood Hits	344	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

VCAM1_MOUSE
NC score	0.207087 (rank : 136)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	181	Target Neighborhood Hits	320	Shared Neighborhood Hits	63
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

GHR_HUMAN
NC score	0.206711 (rank : 137)	θ value	0.0252991 (rank : 121)
Query Neighborhood Hits	181	Target Neighborhood Hits	57	Shared Neighborhood Hits	31
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

TMIGD_HUMAN
NC score	0.206423 (rank : 138)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	181	Target Neighborhood Hits	240	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

MAG_MOUSE
NC score	0.205913 (rank : 139)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	181	Target Neighborhood Hits	271	Shared Neighborhood Hits	67
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_HUMAN
NC score	0.205729 (rank : 140)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	181	Target Neighborhood Hits	278	Shared Neighborhood Hits	67
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

HCFC2_MOUSE
NC score	0.205616 (rank : 141)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	181	Target Neighborhood Hits	97	Shared Neighborhood Hits	77
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

SN_MOUSE
NC score	0.205166 (rank : 142)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	181	Target Neighborhood Hits	416	Shared Neighborhood Hits	74
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

NPTN_HUMAN
NC score	0.204731 (rank : 143)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	181	Target Neighborhood Hits	212	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

ICAM5_MOUSE
NC score	0.203874 (rank : 144)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	181	Target Neighborhood Hits	308	Shared Neighborhood Hits	64
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

FSTL5_HUMAN
NC score	0.202510 (rank : 145)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	181	Target Neighborhood Hits	347	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

COKA1_HUMAN
NC score	0.201873 (rank : 146)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	181	Target Neighborhood Hits	403	Shared Neighborhood Hits	92
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

TMIGD_MOUSE
NC score	0.201824 (rank : 147)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	181	Target Neighborhood Hits	234	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

VCAM1_HUMAN
NC score	0.201761 (rank : 148)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	181	Target Neighborhood Hits	352	Shared Neighborhood Hits	62
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

TENN_HUMAN
NC score	0.201745 (rank : 149)	θ value	1.06291 (rank : 154)
Query Neighborhood Hits	181	Target Neighborhood Hits	453	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

PTPRU_HUMAN
NC score	0.201619 (rank : 150)	θ value	0.62314 (rank : 147)
Query Neighborhood Hits	181	Target Neighborhood Hits	237	Shared Neighborhood Hits	105
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

TARSH_HUMAN
NC score	0.201291 (rank : 151)	θ value	0.0193708 (rank : 118)
Query Neighborhood Hits	181	Target Neighborhood Hits	768	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MUC18_HUMAN
NC score	0.200615 (rank : 152)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	181	Target Neighborhood Hits	275	Shared Neighborhood Hits	64
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

KIRR2_HUMAN
NC score	0.200549 (rank : 153)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	181	Target Neighborhood Hits	321	Shared Neighborhood Hits	65
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

PGBM_HUMAN
NC score	0.200213 (rank : 154)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	181	Target Neighborhood Hits	1113	Shared Neighborhood Hits	98
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KIRR2_MOUSE
NC score	0.200046 (rank : 155)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	181	Target Neighborhood Hits	326	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

FSTL4_MOUSE
NC score	0.199319 (rank : 156)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	181	Target Neighborhood Hits	333	Shared Neighborhood Hits	65
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL4_HUMAN
NC score	0.198425 (rank : 157)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	181	Target Neighborhood Hits	344	Shared Neighborhood Hits	68
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL5_MOUSE
NC score	0.198196 (rank : 158)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	181	Target Neighborhood Hits	355	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

ICAM5_HUMAN
NC score	0.196832 (rank : 159)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	181	Target Neighborhood Hits	276	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

SN_HUMAN
NC score	0.195983 (rank : 160)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	181	Target Neighborhood Hits	434	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

PGBM_MOUSE
NC score	0.195640 (rank : 161)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	181	Target Neighborhood Hits	1073	Shared Neighborhood Hits	98
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PTK7_HUMAN
NC score	0.194092 (rank : 162)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	181	Target Neighborhood Hits	1103	Shared Neighborhood Hits	94
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

KAZD1_MOUSE
NC score	0.193432 (rank : 163)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	181	Target Neighborhood Hits	281	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

LU_HUMAN
NC score	0.193237 (rank : 164)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	181	Target Neighborhood Hits	283	Shared Neighborhood Hits	66
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

RAGE_HUMAN
NC score	0.192960 (rank : 165)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	181	Target Neighborhood Hits	269	Shared Neighborhood Hits	66
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

NPTN_MOUSE
NC score	0.192663 (rank : 166)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	181	Target Neighborhood Hits	216	Shared Neighborhood Hits	61
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

CD22_MOUSE
NC score	0.191278 (rank : 167)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	181	Target Neighborhood Hits	331	Shared Neighborhood Hits	60
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CI094_HUMAN
NC score	0.190775 (rank : 168)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	62
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

MUC18_MOUSE
NC score	0.190379 (rank : 169)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	181	Target Neighborhood Hits	292	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

HMCN1_HUMAN
NC score	0.190184 (rank : 170)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	181	Target Neighborhood Hits	983	Shared Neighborhood Hits	85
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

JAM3_HUMAN
NC score	0.190099 (rank : 171)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	181	Target Neighborhood Hits	271	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAM3_MOUSE
NC score	0.188428 (rank : 172)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	181	Target Neighborhood Hits	286	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

IL3RB_HUMAN
NC score	0.187758 (rank : 173)	θ value	0.0113563 (rank : 114)
Query Neighborhood Hits	181	Target Neighborhood Hits	163	Shared Neighborhood Hits	37
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

BASI_HUMAN
NC score	0.187569 (rank : 174)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	181	Target Neighborhood Hits	211	Shared Neighborhood Hits	60
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

KAZD1_HUMAN
NC score	0.186964 (rank : 175)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	181	Target Neighborhood Hits	248	Shared Neighborhood Hits	60
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

JAM1_HUMAN
NC score	0.185414 (rank : 176)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	181	Target Neighborhood Hits	294	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

BASI_MOUSE
NC score	0.184820 (rank : 177)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	181	Target Neighborhood Hits	238	Shared Neighborhood Hits	57
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

RAGE_MOUSE
NC score	0.184423 (rank : 178)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	181	Target Neighborhood Hits	295	Shared Neighborhood Hits	65
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

EPHA7_MOUSE
NC score	0.182455 (rank : 179)	θ value	5.81887e-07 (rank : 50)
Query Neighborhood Hits	181	Target Neighborhood Hits	1025	Shared Neighborhood Hits	117
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

KIRR1_HUMAN
NC score	0.182424 (rank : 180)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	181	Target Neighborhood Hits	401	Shared Neighborhood Hits	68
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

EPHA7_HUMAN
NC score	0.182098 (rank : 181)	θ value	1.29631e-06 (rank : 55)
Query Neighborhood Hits	181	Target Neighborhood Hits	1053	Shared Neighborhood Hits	116
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

SORL_MOUSE
NC score	0.181100 (rank : 182)	θ value	0.00102713 (rank : 95)
Query Neighborhood Hits	181	Target Neighborhood Hits	439	Shared Neighborhood Hits	106
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

EPOR_MOUSE
NC score	0.180560 (rank : 183)	θ value	0.0330416 (rank : 123)
Query Neighborhood Hits	181	Target Neighborhood Hits	52	Shared Neighborhood Hits	30
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

FCRL5_HUMAN
NC score	0.180373 (rank : 184)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	181	Target Neighborhood Hits	267	Shared Neighborhood Hits	58
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

EPHA8_MOUSE
NC score	0.180231 (rank : 185)	θ value	1.38499e-08 (rank : 35)
Query Neighborhood Hits	181	Target Neighborhood Hits	969	Shared Neighborhood Hits	117
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

KIRR1_MOUSE
NC score	0.180046 (rank : 186)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	181	Target Neighborhood Hits	403	Shared Neighborhood Hits	66
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

SORL_HUMAN
NC score	0.179945 (rank : 187)	θ value	0.00102713 (rank : 94)
Query Neighborhood Hits	181	Target Neighborhood Hits	440	Shared Neighborhood Hits	103
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

KIRR3_HUMAN
NC score	0.179612 (rank : 188)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	181	Target Neighborhood Hits	302	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

CD22_HUMAN
NC score	0.179239 (rank : 189)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	181	Target Neighborhood Hits	365	Shared Neighborhood Hits	61
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

IL21R_HUMAN
NC score	0.179017 (rank : 190)	θ value	0.00869519 (rank : 109)
Query Neighborhood Hits	181	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

PTPRK_MOUSE
NC score	0.178467 (rank : 191)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	181	Target Neighborhood Hits	223	Shared Neighborhood Hits	91
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

JAM1_MOUSE
NC score	0.178327 (rank : 192)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	181	Target Neighborhood Hits	287	Shared Neighborhood Hits	62
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

CEAM5_HUMAN
NC score	0.178084 (rank : 193)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	181	Target Neighborhood Hits	343	Shared Neighborhood Hits	66
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

MUSK_MOUSE
NC score	0.178001 (rank : 194)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	181	Target Neighborhood Hits	1057	Shared Neighborhood Hits	89
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

EPHA8_HUMAN
NC score	0.177553 (rank : 195)	θ value	1.38499e-08 (rank : 34)
Query Neighborhood Hits	181	Target Neighborhood Hits	956	Shared Neighborhood Hits	117
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

VSIG2_HUMAN
NC score	0.177415 (rank : 196)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	181	Target Neighborhood Hits	321	Shared Neighborhood Hits	66
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

MUSK_HUMAN
NC score	0.177357 (rank : 197)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	181	Target Neighborhood Hits	1074	Shared Neighborhood Hits	89
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

PTPRK_HUMAN
NC score	0.175985 (rank : 198)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	181	Target Neighborhood Hits	228	Shared Neighborhood Hits	92
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

IL3B2_MOUSE
NC score	0.175352 (rank : 199)	θ value	5.44631e-05 (rank : 72)
Query Neighborhood Hits	181	Target Neighborhood Hits	372	Shared Neighborhood Hits	43
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

KIRR3_MOUSE
NC score	0.175182 (rank : 200)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	181	Target Neighborhood Hits	292	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

EPHA3_MOUSE
NC score	0.174903 (rank : 201)	θ value	0.00035302 (rank : 84)
Query Neighborhood Hits	181	Target Neighborhood Hits	1009	Shared Neighborhood Hits	125
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHB6_HUMAN
NC score	0.173819 (rank : 202)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	181	Target Neighborhood Hits	912	Shared Neighborhood Hits	106
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

MFA3L_HUMAN
NC score	0.173686 (rank : 203)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	181	Target Neighborhood Hits	230	Shared Neighborhood Hits	61
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

I12R1_HUMAN
NC score	0.173141 (rank : 204)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	181	Target Neighborhood Hits	78	Shared Neighborhood Hits	61
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

TENA_HUMAN
NC score	0.172995 (rank : 205)	θ value	0.62314 (rank : 148)
Query Neighborhood Hits	181	Target Neighborhood Hits	631	Shared Neighborhood Hits	113
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

UFO_MOUSE
NC score	0.172561 (rank : 206)	θ value	9.29e-05 (rank : 78)
Query Neighborhood Hits	181	Target Neighborhood Hits	988	Shared Neighborhood Hits	113
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

LRIG2_HUMAN
NC score	0.172449 (rank : 207)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	181	Target Neighborhood Hits	595	Shared Neighborhood Hits	70
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
NC score	0.171996 (rank : 208)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	181	Target Neighborhood Hits	586	Shared Neighborhood Hits	70
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

CEA20_HUMAN
NC score	0.171754 (rank : 209)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	181	Target Neighborhood Hits	251	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

EPHA4_MOUSE
NC score	0.171456 (rank : 210)	θ value	0.000786445 (rank : 89)
Query Neighborhood Hits	181	Target Neighborhood Hits	982	Shared Neighborhood Hits	111
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

MERTK_HUMAN
NC score	0.171374 (rank : 211)	θ value	0.00665767 (rank : 108)
Query Neighborhood Hits	181	Target Neighborhood Hits	988	Shared Neighborhood Hits	105
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

EPHB6_MOUSE
NC score	0.171046 (rank : 212)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	181	Target Neighborhood Hits	906	Shared Neighborhood Hits	99
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

LRIG1_HUMAN
NC score	0.170864 (rank : 213)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	181	Target Neighborhood Hits	654	Shared Neighborhood Hits	69
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

EPHA4_HUMAN
NC score	0.170844 (rank : 214)	θ value	0.00020696 (rank : 80)
Query Neighborhood Hits	181	Target Neighborhood Hits	975	Shared Neighborhood Hits	109
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

IBP7_HUMAN
NC score	0.170672 (rank : 215)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	181	Target Neighborhood Hits	220	Shared Neighborhood Hits	59
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IL2RG_MOUSE
NC score	0.170650 (rank : 216)	θ value	5.44631e-05 (rank : 71)
Query Neighborhood Hits	181	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

EPHA5_HUMAN
NC score	0.170510 (rank : 217)	θ value	0.00102713 (rank : 92)
Query Neighborhood Hits	181	Target Neighborhood Hits	1009	Shared Neighborhood Hits	115
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHA3_HUMAN
NC score	0.170110 (rank : 218)	θ value	0.00035302 (rank : 83)
Query Neighborhood Hits	181	Target Neighborhood Hits	1005	Shared Neighborhood Hits	122
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

TYRO3_HUMAN
NC score	0.170003 (rank : 219)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	181	Target Neighborhood Hits	995	Shared Neighborhood Hits	108
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

VSIG2_MOUSE
NC score	0.169812 (rank : 220)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	181	Target Neighborhood Hits	316	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

TYRO3_MOUSE
NC score	0.169595 (rank : 221)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	181	Target Neighborhood Hits	1007	Shared Neighborhood Hits	107
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

CEAM1_MOUSE
NC score	0.169092 (rank : 222)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	181	Target Neighborhood Hits	326	Shared Neighborhood Hits	64
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

FCRL2_HUMAN
NC score	0.168997 (rank : 223)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	181	Target Neighborhood Hits	251	Shared Neighborhood Hits	60
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

IBP7_MOUSE
NC score	0.168968 (rank : 224)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	181	Target Neighborhood Hits	230	Shared Neighborhood Hits	63
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

LRIG1_MOUSE
NC score	0.168630 (rank : 225)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	181	Target Neighborhood Hits	627	Shared Neighborhood Hits	68
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

MERTK_MOUSE
NC score	0.168525 (rank : 226)	θ value	0.00134147 (rank : 97)
Query Neighborhood Hits	181	Target Neighborhood Hits	974	Shared Neighborhood Hits	108
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

EPHB3_MOUSE
NC score	0.167243 (rank : 227)	θ value	0.0961366 (rank : 128)
Query Neighborhood Hits	181	Target Neighborhood Hits	996	Shared Neighborhood Hits	117
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

JAM2_HUMAN
NC score	0.166913 (rank : 228)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	181	Target Neighborhood Hits	304	Shared Neighborhood Hits	66
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

TENX_HUMAN
NC score	0.166727 (rank : 229)	θ value	0.163984 (rank : 137)
Query Neighborhood Hits	181	Target Neighborhood Hits	789	Shared Neighborhood Hits	113
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LRIG3_MOUSE
NC score	0.165972 (rank : 230)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	181	Target Neighborhood Hits	611	Shared Neighborhood Hits	70
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

EPHB3_HUMAN
NC score	0.165164 (rank : 231)	θ value	0.62314 (rank : 146)
Query Neighborhood Hits	181	Target Neighborhood Hits	996	Shared Neighborhood Hits	114
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

LRIG3_HUMAN
NC score	0.164914 (rank : 232)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	181	Target Neighborhood Hits	601	Shared Neighborhood Hits	71
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

IL2RG_HUMAN
NC score	0.164477 (rank : 233)	θ value	0.00298849 (rank : 102)
Query Neighborhood Hits	181	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

GHR_MOUSE
NC score	0.161892 (rank : 234)	θ value	0.365318 (rank : 141)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	26
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

EPHA6_HUMAN
NC score	0.160153 (rank : 235)	θ value	4.1701e-05 (rank : 68)
Query Neighborhood Hits	181	Target Neighborhood Hits	959	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

MYLK_HUMAN
NC score	0.159748 (rank : 236)	θ value	0.00134147 (rank : 98)
Query Neighborhood Hits	181	Target Neighborhood Hits	1328	Shared Neighborhood Hits	107
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

IGS4B_MOUSE
NC score	0.159670 (rank : 237)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	181	Target Neighborhood Hits	328	Shared Neighborhood Hits	63
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

EPOR_HUMAN
NC score	0.159519 (rank : 238)	θ value	5.27518 (rank : 169)
Query Neighborhood Hits	181	Target Neighborhood Hits	58	Shared Neighborhood Hits	35
SwissProt Accessions	P19235, Q15443	Gene names	EPOR
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

EPHB1_HUMAN
NC score	0.158649 (rank : 239)	θ value	0.00665767 (rank : 107)
Query Neighborhood Hits	181	Target Neighborhood Hits	988	Shared Neighborhood Hits	110
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

SIG10_HUMAN
NC score	0.157995 (rank : 240)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	181	Target Neighborhood Hits	363	Shared Neighborhood Hits	63
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

MYLK_MOUSE
NC score	0.157760 (rank : 241)	θ value	0.00228821 (rank : 101)
Query Neighborhood Hits	181	Target Neighborhood Hits	1489	Shared Neighborhood Hits	107
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

UFO_HUMAN
NC score	0.157636 (rank : 242)	θ value	0.00869519 (rank : 113)
Query Neighborhood Hits	181	Target Neighborhood Hits	981	Shared Neighborhood Hits	109
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

JAM2_MOUSE
NC score	0.157446 (rank : 243)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	181	Target Neighborhood Hits	292	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

SIG11_HUMAN
NC score	0.157355 (rank : 244)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	181	Target Neighborhood Hits	273	Shared Neighborhood Hits	64
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

IL3RB_MOUSE
NC score	0.156387 (rank : 245)	θ value	0.00869519 (rank : 110)
Query Neighborhood Hits	181	Target Neighborhood Hits	355	Shared Neighborhood Hits	39
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

EPHB4_MOUSE
NC score	0.155830 (rank : 246)	θ value	0.163984 (rank : 135)
Query Neighborhood Hits	181	Target Neighborhood Hits	1013	Shared Neighborhood Hits	110
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHA6_MOUSE
NC score	0.155830 (rank : 247)	θ value	7.1131e-05 (rank : 75)
Query Neighborhood Hits	181	Target Neighborhood Hits	946	Shared Neighborhood Hits	91
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

IGS4B_HUMAN
NC score	0.155596 (rank : 248)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	181	Target Neighborhood Hits	305	Shared Neighborhood Hits	64
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

EPHB4_HUMAN
NC score	0.155050 (rank : 249)	θ value	0.0148317 (rank : 115)
Query Neighborhood Hits	181	Target Neighborhood Hits	1056	Shared Neighborhood Hits	113
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

TENA_MOUSE
NC score	0.154519 (rank : 250)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	181	Target Neighborhood Hits	596	Shared Neighborhood Hits	109
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

EPHB2_HUMAN
NC score	0.154209 (rank : 251)	θ value	0.00509761 (rank : 104)
Query Neighborhood Hits	181	Target Neighborhood Hits	983	Shared Neighborhood Hits	101
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
NC score	0.154197 (rank : 252)	θ value	0.00509761 (rank : 105)
Query Neighborhood Hits	181	Target Neighborhood Hits	982	Shared Neighborhood Hits	101
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

NRG2_HUMAN
NC score	0.154005 (rank : 253)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	181	Target Neighborhood Hits	419	Shared Neighborhood Hits	66
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

IL21R_MOUSE
NC score	0.153798 (rank : 254)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

NRG2_MOUSE
NC score	0.153111 (rank : 255)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	181	Target Neighborhood Hits	392	Shared Neighborhood Hits	66
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

EPHA2_HUMAN
NC score	0.152093 (rank : 256)	θ value	0.000786445 (rank : 88)
Query Neighborhood Hits	181	Target Neighborhood Hits	1021	Shared Neighborhood Hits	112
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

MFA3L_MOUSE
NC score	0.151210 (rank : 257)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	181	Target Neighborhood Hits	214	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

EPHA5_MOUSE
NC score	0.149252 (rank : 258)	θ value	0.000158464 (rank : 79)
Query Neighborhood Hits	181	Target Neighborhood Hits	950	Shared Neighborhood Hits	105
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

EPHA2_MOUSE
NC score	0.149074 (rank : 259)	θ value	5.44631e-05 (rank : 70)
Query Neighborhood Hits	181	Target Neighborhood Hits	1020	Shared Neighborhood Hits	108
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

CEAM1_HUMAN
NC score	0.148919 (rank : 260)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	181	Target Neighborhood Hits	348	Shared Neighborhood Hits	64
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

VGFR1_HUMAN
NC score	0.146607 (rank : 261)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	181	Target Neighborhood Hits	1109	Shared Neighborhood Hits	89
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

VGFR1_MOUSE
NC score	0.145676 (rank : 262)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	181	Target Neighborhood Hits	1118	Shared Neighborhood Hits	90
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

TIE1_MOUSE
NC score	0.143979 (rank : 263)	θ value	0.00102713 (rank : 96)
Query Neighborhood Hits	181	Target Neighborhood Hits	1266	Shared Neighborhood Hits	117
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TPOR_HUMAN
NC score	0.142211 (rank : 264)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	181	Target Neighborhood Hits	70	Shared Neighborhood Hits	43
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

OBSCN_HUMAN
NC score	0.140353 (rank : 265)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	181	Target Neighborhood Hits	1931	Shared Neighborhood Hits	117
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

EPHAA_HUMAN
NC score	0.139673 (rank : 266)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	181	Target Neighborhood Hits	960	Shared Neighborhood Hits	88
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

FGFR4_MOUSE
NC score	0.139371 (rank : 267)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	181	Target Neighborhood Hits	1026	Shared Neighborhood Hits	92
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

ROS_HUMAN
NC score	0.139354 (rank : 268)	θ value	0.0252991 (rank : 122)
Query Neighborhood Hits	181	Target Neighborhood Hits	907	Shared Neighborhood Hits	116
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

VGFR2_HUMAN
NC score	0.138588 (rank : 269)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	181	Target Neighborhood Hits	1103	Shared Neighborhood Hits	89
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

SPEG_MOUSE
NC score	0.137454 (rank : 270)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	181	Target Neighborhood Hits	1959	Shared Neighborhood Hits	105
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TIE2_MOUSE
NC score	0.137130 (rank : 271)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	181	Target Neighborhood Hits	1204	Shared Neighborhood Hits	113
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

VGFR2_MOUSE
NC score	0.137058 (rank : 272)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	181	Target Neighborhood Hits	1089	Shared Neighborhood Hits	89
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

PTPRJ_MOUSE
NC score	0.137030 (rank : 273)	θ value	0.0736092 (rank : 127)
Query Neighborhood Hits	181	Target Neighborhood Hits	188	Shared Neighborhood Hits	71
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRB_HUMAN
NC score	0.136978 (rank : 274)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	181	Target Neighborhood Hits	242	Shared Neighborhood Hits	81
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

ATL3_HUMAN
NC score	0.136917 (rank : 275)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	181	Target Neighborhood Hits	414	Shared Neighborhood Hits	67
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

FGFR4_HUMAN
NC score	0.136299 (rank : 276)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	181	Target Neighborhood Hits	1037	Shared Neighborhood Hits	91
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

SPEG_HUMAN
NC score	0.135838 (rank : 277)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	181	Target Neighborhood Hits	1762	Shared Neighborhood Hits	103
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

VSIG4_HUMAN
NC score	0.135465 (rank : 278)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	181	Target Neighborhood Hits	236	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

HCFC2_HUMAN
NC score	0.135203 (rank : 279)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	181	Target Neighborhood Hits	154	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

FGFR3_MOUSE
NC score	0.135098 (rank : 280)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	181	Target Neighborhood Hits	1059	Shared Neighborhood Hits	91
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

IL1R2_HUMAN
NC score	0.134895 (rank : 281)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	181	Target Neighborhood Hits	153	Shared Neighborhood Hits	49
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

CD166_MOUSE
NC score	0.134019 (rank : 282)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	181	Target Neighborhood Hits	252	Shared Neighborhood Hits	56
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

PTPRJ_HUMAN
NC score	0.133841 (rank : 283)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	181	Target Neighborhood Hits	207	Shared Neighborhood Hits	75
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

TIE1_HUMAN
NC score	0.133212 (rank : 284)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	181	Target Neighborhood Hits	1241	Shared Neighborhood Hits	116
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

FGFR1_HUMAN
NC score	0.132642 (rank : 285)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	181	Target Neighborhood Hits	1069	Shared Neighborhood Hits	89
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR2_HUMAN
NC score	0.132467 (rank : 286)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	181	Target Neighborhood Hits	1062	Shared Neighborhood Hits	89
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

FGFR1_MOUSE
NC score	0.132420 (rank : 287)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	181	Target Neighborhood Hits	1068	Shared Neighborhood Hits	89
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

GPA33_MOUSE
NC score	0.132363 (rank : 288)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	181	Target Neighborhood Hits	294	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

TIE2_HUMAN
NC score	0.132072 (rank : 289)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	181	Target Neighborhood Hits	1192	Shared Neighborhood Hits	114
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

FGFR3_HUMAN
NC score	0.131718 (rank : 290)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	181	Target Neighborhood Hits	1042	Shared Neighborhood Hits	89
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

IL5RA_HUMAN
NC score	0.130543 (rank : 291)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	181	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	Q01344, Q6ISX9	Gene names	IL5RA, IL5R
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen) (CDw125).

CEAM6_HUMAN
NC score	0.128026 (rank : 292)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	181	Target Neighborhood Hits	308	Shared Neighborhood Hits	65
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

FGFR2_MOUSE
NC score	0.127885 (rank : 293)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	181	Target Neighborhood Hits	1062	Shared Neighborhood Hits	89
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

I12R1_MOUSE
NC score	0.127270 (rank : 294)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	181	Target Neighborhood Hits	70	Shared Neighborhood Hits	47
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

SIGL5_MOUSE
NC score	0.127266 (rank : 295)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	181	Target Neighborhood Hits	271	Shared Neighborhood Hits	60
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

ROR2_MOUSE
NC score	0.125511 (rank : 296)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	181	Target Neighborhood Hits	1000	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

TPOR_MOUSE
NC score	0.124964 (rank : 297)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	181	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

PTPRV_MOUSE
NC score	0.124453 (rank : 298)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	181	Target Neighborhood Hits	179	Shared Neighborhood Hits	65
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

GPA33_HUMAN
NC score	0.123992 (rank : 299)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	181	Target Neighborhood Hits	273	Shared Neighborhood Hits	50
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

EPHA1_MOUSE
NC score	0.123605 (rank : 300)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	181	Target Neighborhood Hits	958	Shared Neighborhood Hits	87
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

DUET_HUMAN
NC score	0.122084 (rank : 301)	θ value	0.163984 (rank : 134)
Query Neighborhood Hits	181	Target Neighborhood Hits	1220	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ROR2_HUMAN
NC score	0.122033 (rank : 302)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	181	Target Neighborhood Hits	1014	Shared Neighborhood Hits	89
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

IL4RA_HUMAN
NC score	0.120650 (rank : 303)	θ value	0.00509761 (rank : 106)
Query Neighborhood Hits	181	Target Neighborhood Hits	144	Shared Neighborhood Hits	27
SwissProt Accessions	P24394, Q96P01, Q9H181, Q9H182, Q9H183, Q9H184, Q9H185, Q9H186, Q9H187, Q9H188	Gene names	IL4R, 582J2.1, IL4RA
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)].

CD166_HUMAN
NC score	0.120194 (rank : 304)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	181	Target Neighborhood Hits	247	Shared Neighborhood Hits	54
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

CILP2_HUMAN
NC score	0.119680 (rank : 305)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	181	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

EPHA1_HUMAN
NC score	0.119324 (rank : 306)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	181	Target Neighborhood Hits	997	Shared Neighborhood Hits	78
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

VGFR3_HUMAN
NC score	0.119276 (rank : 307)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	181	Target Neighborhood Hits	1037	Shared Neighborhood Hits	91
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

ROR1_HUMAN
NC score	0.119163 (rank : 308)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	181	Target Neighborhood Hits	1018	Shared Neighborhood Hits	89
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
NC score	0.117849 (rank : 309)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	181	Target Neighborhood Hits	1025	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

VGFR3_MOUSE
NC score	0.116838 (rank : 310)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	181	Target Neighborhood Hits	1056	Shared Neighborhood Hits	89
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

UNC5D_MOUSE
NC score	0.116336 (rank : 311)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	181	Target Neighborhood Hits	268	Shared Neighborhood Hits	65
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

NTRK2_HUMAN
NC score	0.116011 (rank : 312)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	181	Target Neighborhood Hits	1081	Shared Neighborhood Hits	87
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

CSF1R_MOUSE
NC score	0.115560 (rank : 313)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	181	Target Neighborhood Hits	983	Shared Neighborhood Hits	85
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

PSG3_HUMAN
NC score	0.115395 (rank : 314)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	181	Target Neighborhood Hits	242	Shared Neighborhood Hits	63
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

NTRK2_MOUSE
NC score	0.115284 (rank : 315)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	181	Target Neighborhood Hits	1088	Shared Neighborhood Hits	87
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

LRFN4_HUMAN
NC score	0.113674 (rank : 316)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	181	Target Neighborhood Hits	462	Shared Neighborhood Hits	72
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

NTRK3_HUMAN
NC score	0.113268 (rank : 317)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	181	Target Neighborhood Hits	1115	Shared Neighborhood Hits	89
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

UNC5D_HUMAN
NC score	0.112551 (rank : 318)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	181	Target Neighborhood Hits	267	Shared Neighborhood Hits	63
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

PSG4_HUMAN
NC score	0.112166 (rank : 319)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	181	Target Neighborhood Hits	243	Shared Neighborhood Hits	59
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

PSG8_HUMAN
NC score	0.111998 (rank : 320)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	181	Target Neighborhood Hits	239	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

IL1R2_MOUSE
NC score	0.111881 (rank : 321)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	181	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IL5RA_MOUSE
NC score	0.111141 (rank : 322)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	181	Target Neighborhood Hits	33	Shared Neighborhood Hits	25
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

UNC5A_HUMAN
NC score	0.111029 (rank : 323)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	181	Target Neighborhood Hits	198	Shared Neighborhood Hits	58
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

LRFN4_MOUSE
NC score	0.110483 (rank : 324)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	181	Target Neighborhood Hits	442	Shared Neighborhood Hits	69
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRC21_MOUSE
NC score	0.109511 (rank : 325)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	181	Target Neighborhood Hits	462	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

IRPL2_HUMAN
NC score	0.109162 (rank : 326)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	181	Target Neighborhood Hits	194	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

INAR1_MOUSE
NC score	0.108797 (rank : 327)	θ value	0.00228821 (rank : 100)
Query Neighborhood Hits	181	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	P33896	Gene names	Ifnar1, Ifar, Ifnar
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

PGFRA_MOUSE
NC score	0.108536 (rank : 328)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	181	Target Neighborhood Hits	975	Shared Neighborhood Hits	85
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

IRPL2_MOUSE
NC score	0.108457 (rank : 329)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	181	Target Neighborhood Hits	195	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

PGFRA_HUMAN
NC score	0.108122 (rank : 330)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	181	Target Neighborhood Hits	980	Shared Neighborhood Hits	84
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

LRFN2_MOUSE
NC score	0.107994 (rank : 331)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	181	Target Neighborhood Hits	450	Shared Neighborhood Hits	70
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

CEAM8_HUMAN
NC score	0.107611 (rank : 332)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	181	Target Neighborhood Hits	264	Shared Neighborhood Hits	62
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

LRFN2_HUMAN
NC score	0.106587 (rank : 333)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	181	Target Neighborhood Hits	450	Shared Neighborhood Hits	69
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

PSG6_HUMAN
NC score	0.105858 (rank : 334)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	181	Target Neighborhood Hits	231	Shared Neighborhood Hits	59
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

NRG1_HUMAN
NC score	0.105772 (rank : 335)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	181	Target Neighborhood Hits	285	Shared Neighborhood Hits	56
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

KIT_MOUSE
NC score	0.105733 (rank : 336)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	181	Target Neighborhood Hits	949	Shared Neighborhood Hits	84
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

PSG7_HUMAN
NC score	0.105696 (rank : 337)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	181	Target Neighborhood Hits	239	Shared Neighborhood Hits	60
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

IL4RA_MOUSE
NC score	0.105387 (rank : 338)	θ value	0.365318 (rank : 142)
Query Neighborhood Hits	181	Target Neighborhood Hits	194	Shared Neighborhood Hits	22
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

PSG1_HUMAN
NC score	0.105331 (rank : 339)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	181	Target Neighborhood Hits	232	Shared Neighborhood Hits	61
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

IL2RB_MOUSE
NC score	0.104447 (rank : 340)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	181	Target Neighborhood Hits	51	Shared Neighborhood Hits	25
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

CXAR_HUMAN
NC score	0.104388 (rank : 341)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	181	Target Neighborhood Hits	245	Shared Neighborhood Hits	44
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

IRPL1_MOUSE
NC score	0.104270 (rank : 342)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	181	Target Neighborhood Hits	186	Shared Neighborhood Hits	56
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

PSG10_HUMAN
NC score	0.104243 (rank : 343)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

INSRR_HUMAN
NC score	0.103888 (rank : 344)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	181	Target Neighborhood Hits	950	Shared Neighborhood Hits	79
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

PGFRB_MOUSE
NC score	0.103528 (rank : 345)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	181	Target Neighborhood Hits	960	Shared Neighborhood Hits	80
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PTPRO_HUMAN
NC score	0.103250 (rank : 346)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	181	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

UNC5C_MOUSE
NC score	0.103041 (rank : 347)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	181	Target Neighborhood Hits	225	Shared Neighborhood Hits	62
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

LRC21_HUMAN
NC score	0.103031 (rank : 348)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	181	Target Neighborhood Hits	456	Shared Neighborhood Hits	77
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

UNC5C_HUMAN
NC score	0.102717 (rank : 349)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	181	Target Neighborhood Hits	226	Shared Neighborhood Hits	60
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

INSRR_MOUSE
NC score	0.102474 (rank : 350)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	181	Target Neighborhood Hits	961	Shared Neighborhood Hits	78
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

CD276_HUMAN
NC score	0.102023 (rank : 351)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	181	Target Neighborhood Hits	261	Shared Neighborhood Hits	42
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

PSG11_HUMAN
NC score	0.101826 (rank : 352)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	181	Target Neighborhood Hits	223	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

LRFN3_MOUSE
NC score	0.101084 (rank : 353)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	181	Target Neighborhood Hits	455	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

CILP1_MOUSE
NC score	0.100812 (rank : 354)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	181	Target Neighborhood Hits	282	Shared Neighborhood Hits	60
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

KIT_HUMAN
NC score	0.100164 (rank : 355)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	181	Target Neighborhood Hits	953	Shared Neighborhood Hits	83
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

EMB_MOUSE
NC score	0.099796 (rank : 356)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	181	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

IL2RB_HUMAN
NC score	0.099424 (rank : 357)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	181	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

PSG9_HUMAN
NC score	0.098553 (rank : 358)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	181	Target Neighborhood Hits	221	Shared Neighborhood Hits	57
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

CXAR_MOUSE
NC score	0.098305 (rank : 359)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	181	Target Neighborhood Hits	250	Shared Neighborhood Hits	48
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

PSG2_HUMAN
NC score	0.097879 (rank : 360)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	181	Target Neighborhood Hits	229	Shared Neighborhood Hits	60
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

CILP1_HUMAN
NC score	0.097407 (rank : 361)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	181	Target Neighborhood Hits	266	Shared Neighborhood Hits	61
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

IL12B_HUMAN
NC score	0.097237 (rank : 362)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	181	Target Neighborhood Hits	51	Shared Neighborhood Hits	14
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

IGF1R_HUMAN
NC score	0.097233 (rank : 363)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	181	Target Neighborhood Hits	977	Shared Neighborhood Hits	80
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IRPL1_HUMAN
NC score	0.097089 (rank : 364)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	181	Target Neighborhood Hits	196	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

UNC5B_HUMAN
NC score	0.096927 (rank : 365)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	181	Target Neighborhood Hits	225	Shared Neighborhood Hits	60
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

INSR_MOUSE
NC score	0.096898 (rank : 366)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	181	Target Neighborhood Hits	968	Shared Neighborhood Hits	78
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

ESAM_HUMAN
NC score	0.096839 (rank : 367)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	181	Target Neighborhood Hits	251	Shared Neighborhood Hits	52
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

IGF1R_MOUSE
NC score	0.096575 (rank : 368)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	181	Target Neighborhood Hits	973	Shared Neighborhood Hits	81
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

LRFN5_MOUSE
NC score	0.096487 (rank : 369)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	181	Target Neighborhood Hits	472	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRFN3_HUMAN
NC score	0.096296 (rank : 370)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	181	Target Neighborhood Hits	444	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

UNC5A_MOUSE
NC score	0.096216 (rank : 371)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	181	Target Neighborhood Hits	203	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

PGFRB_HUMAN
NC score	0.095771 (rank : 372)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	181	Target Neighborhood Hits	962	Shared Neighborhood Hits	83
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

SIGL5_HUMAN
NC score	0.095742 (rank : 373)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	181	Target Neighborhood Hits	246	Shared Neighborhood Hits	54
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

UNC5B_MOUSE
NC score	0.095627 (rank : 374)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	181	Target Neighborhood Hits	226	Shared Neighborhood Hits	60
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

PDL1_HUMAN
NC score	0.095252 (rank : 375)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	181	Target Neighborhood Hits	195	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

ANKF1_HUMAN
NC score	0.095031 (rank : 376)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	181	Target Neighborhood Hits	126	Shared Neighborhood Hits	35
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

LRFN5_HUMAN
NC score	0.094090 (rank : 377)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	181	Target Neighborhood Hits	464	Shared Neighborhood Hits	65
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

PIGR_HUMAN
NC score	0.094032 (rank : 378)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	181	Target Neighborhood Hits	164	Shared Neighborhood Hits	42
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

INSR_HUMAN
NC score	0.093826 (rank : 379)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	181	Target Neighborhood Hits	963	Shared Neighborhood Hits	74
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

HCFC1_MOUSE
NC score	0.093453 (rank : 380)	θ value	1.81305 (rank : 157)
Query Neighborhood Hits	181	Target Neighborhood Hits	348	Shared Neighborhood Hits	50
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

RIMB2_HUMAN
NC score	0.091807 (rank : 381)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	181	Target Neighborhood Hits	263	Shared Neighborhood Hits	46
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

CSF1R_HUMAN
NC score	0.091723 (rank : 382)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	181	Target Neighborhood Hits	943	Shared Neighborhood Hits	78
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

ESAM_MOUSE
NC score	0.091366 (rank : 383)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	181	Target Neighborhood Hits	222	Shared Neighborhood Hits	48
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

CD45_HUMAN
NC score	0.091342 (rank : 384)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	181	Target Neighborhood Hits	243	Shared Neighborhood Hits	43
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PIGR_MOUSE
NC score	0.091278 (rank : 385)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	181	Target Neighborhood Hits	214	Shared Neighborhood Hits	44
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

IL12B_MOUSE
NC score	0.090859 (rank : 386)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

CD45_MOUSE
NC score	0.090578 (rank : 387)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	181	Target Neighborhood Hits	178	Shared Neighborhood Hits	42
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

LRRN1_HUMAN
NC score	0.089662 (rank : 388)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	181	Target Neighborhood Hits	518	Shared Neighborhood Hits	70
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

RIMB2_MOUSE
NC score	0.089137 (rank : 389)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	181	Target Neighborhood Hits	246	Shared Neighborhood Hits	43
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SIGL8_HUMAN
NC score	0.088958 (rank : 390)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	181	Target Neighborhood Hits	252	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

PSG5_HUMAN
NC score	0.086990 (rank : 391)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	181	Target Neighborhood Hits	231	Shared Neighborhood Hits	58
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

PTPRG_HUMAN
NC score	0.085482 (rank : 392)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	181	Target Neighborhood Hits	231	Shared Neighborhood Hits	42
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

LRRN1_MOUSE
NC score	0.085456 (rank : 393)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	181	Target Neighborhood Hits	508	Shared Neighborhood Hits	70
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

MOX2R_MOUSE
NC score	0.085352 (rank : 394)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	181	Target Neighborhood Hits	110	Shared Neighborhood Hits	36
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

CSF2R_HUMAN
NC score	0.085267 (rank : 395)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	181	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	P15509, O00207, Q14429, Q14430, Q14431, Q16564	Gene names	CSF2RA, CSF2R
Domain Architecture	No domain graphic available
Description	Granulocyte-macrophage colony-stimulating factor receptor alpha chain precursor (GM-CSF-R-alpha) (GMR) (CD116 antigen) (CDw116).

PTPRG_MOUSE
NC score	0.084359 (rank : 396)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	181	Target Neighborhood Hits	260	Shared Neighborhood Hits	40
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

IL1R1_HUMAN
NC score	0.084297 (rank : 397)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	44
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

IGS21_HUMAN
NC score	0.084096 (rank : 398)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	181	Target Neighborhood Hits	123	Shared Neighborhood Hits	39
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

NTRK1_HUMAN
NC score	0.083960 (rank : 399)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	181	Target Neighborhood Hits	1023	Shared Neighborhood Hits	75
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

TRI42_HUMAN
NC score	0.083840 (rank : 400)	θ value	0.0961366 (rank : 131)
Query Neighborhood Hits	181	Target Neighborhood Hits	283	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

LRRN3_HUMAN
NC score	0.083709 (rank : 401)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	181	Target Neighborhood Hits	461	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

ILRL2_MOUSE
NC score	0.082480 (rank : 402)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	181	Target Neighborhood Hits	158	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

IGS21_MOUSE
NC score	0.081639 (rank : 403)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	181	Target Neighborhood Hits	118	Shared Neighborhood Hits	38
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

LRRN3_MOUSE
NC score	0.081623 (rank : 404)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	181	Target Neighborhood Hits	455	Shared Neighborhood Hits	68
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

IL1R1_MOUSE
NC score	0.081495 (rank : 405)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	181	Target Neighborhood Hits	142	Shared Neighborhood Hits	51
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

CRLF2_MOUSE
NC score	0.079870 (rank : 406)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	181	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CII9, Q9CRJ6, Q9JIE7, Q9JIQ7, Q9JJH8, Q9JMD5	Gene names	Crlf2, Crlm2, Tpte2, Tslpr
Domain Architecture
Description	Cytokine receptor-like factor 2 precursor (Type I cytokine receptor delta 1) (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

PTPRZ_HUMAN
NC score	0.079358 (rank : 407)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	181	Target Neighborhood Hits	255	Shared Neighborhood Hits	31
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

CD79A_HUMAN
NC score	0.079053 (rank : 408)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	34
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

PECA1_HUMAN
NC score	0.078882 (rank : 409)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	181	Target Neighborhood Hits	178	Shared Neighborhood Hits	43
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

SIG12_HUMAN
NC score	0.077388 (rank : 410)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	181	Target Neighborhood Hits	245	Shared Neighborhood Hits	60
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

PGFRL_HUMAN
NC score	0.077331 (rank : 411)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	181	Target Neighborhood Hits	115	Shared Neighborhood Hits	42
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

PTPRE_MOUSE
NC score	0.076440 (rank : 412)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	181	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.076379 (rank : 413)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	181	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

CT075_HUMAN
NC score	0.076357 (rank : 414)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	181	Target Neighborhood Hits	387	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

PTPRA_MOUSE
NC score	0.076296 (rank : 415)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	9
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

FLT3_MOUSE
NC score	0.076207 (rank : 416)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	181	Target Neighborhood Hits	847	Shared Neighborhood Hits	58
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

PTPRE_HUMAN
NC score	0.076202 (rank : 417)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

LRRN5_HUMAN
NC score	0.075779 (rank : 418)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	181	Target Neighborhood Hits	493	Shared Neighborhood Hits	65
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

SIGL6_HUMAN
NC score	0.075159 (rank : 419)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	181	Target Neighborhood Hits	233	Shared Neighborhood Hits	57
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

HHLA2_HUMAN
NC score	0.074451 (rank : 420)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

JAML1_MOUSE
NC score	0.074038 (rank : 421)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	181	Target Neighborhood Hits	185	Shared Neighborhood Hits	33
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

ILRL1_HUMAN
NC score	0.073896 (rank : 422)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	181	Target Neighborhood Hits	167	Shared Neighborhood Hits	44
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

CEAM7_HUMAN
NC score	0.072624 (rank : 423)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	181	Target Neighborhood Hits	170	Shared Neighborhood Hits	51
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

HCFC1_HUMAN
NC score	0.071958 (rank : 424)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	181	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

RYK_HUMAN
NC score	0.071916 (rank : 425)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	181	Target Neighborhood Hits	701	Shared Neighborhood Hits	28
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

LTK_MOUSE
NC score	0.071877 (rank : 426)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	181	Target Neighborhood Hits	770	Shared Neighborhood Hits	31
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LTK_HUMAN
NC score	0.071491 (rank : 427)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	181	Target Neighborhood Hits	774	Shared Neighborhood Hits	31
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

RYK_MOUSE
NC score	0.070949 (rank : 428)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	181	Target Neighborhood Hits	715	Shared Neighborhood Hits	28
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

PVRL3_MOUSE
NC score	0.070701 (rank : 429)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	181	Target Neighborhood Hits	212	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

ALK_MOUSE
NC score	0.070689 (rank : 430)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	181	Target Neighborhood Hits	811	Shared Neighborhood Hits	36
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

TRI42_MOUSE
NC score	0.070442 (rank : 431)	θ value	0.163984 (rank : 138)
Query Neighborhood Hits	181	Target Neighborhood Hits	316	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ALK_HUMAN
NC score	0.070294 (rank : 432)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	181	Target Neighborhood Hits	795	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

PDL1_MOUSE
NC score	0.069918 (rank : 433)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	181	Target Neighborhood Hits	168	Shared Neighborhood Hits	42
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_MOUSE
NC score	0.069518 (rank : 434)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	181	Target Neighborhood Hits	116	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

LRC24_HUMAN
NC score	0.068645 (rank : 435)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	181	Target Neighborhood Hits	404	Shared Neighborhood Hits	60
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

DDR1_HUMAN
NC score	0.068321 (rank : 436)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	181	Target Neighborhood Hits	819	Shared Neighborhood Hits	33
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

I10R2_MOUSE
NC score	0.068179 (rank : 437)	θ value	0.21417 (rank : 139)
Query Neighborhood Hits	181	Target Neighborhood Hits	52	Shared Neighborhood Hits	18
SwissProt Accessions	Q61190	Gene names	Il10rb, Crfb4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

TNK1_HUMAN
NC score	0.068008 (rank : 438)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	181	Target Neighborhood Hits	815	Shared Neighborhood Hits	31
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

CD276_MOUSE
NC score	0.067231 (rank : 439)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	181	Target Neighborhood Hits	243	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

IL9R_MOUSE
NC score	0.067223 (rank : 440)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	181	Target Neighborhood Hits	38	Shared Neighborhood Hits	21
SwissProt Accessions	Q01114	Gene names	Il9r
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

FAK2_HUMAN
NC score	0.067167 (rank : 441)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	181	Target Neighborhood Hits	847	Shared Neighborhood Hits	31
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

DDR1_MOUSE
NC score	0.066998 (rank : 442)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	181	Target Neighborhood Hits	818	Shared Neighborhood Hits	33
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

FAK1_HUMAN
NC score	0.066786 (rank : 443)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	181	Target Neighborhood Hits	850	Shared Neighborhood Hits	31
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

TRIO_HUMAN
NC score	0.066777 (rank : 444)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	181	Target Neighborhood Hits	1580	Shared Neighborhood Hits	88
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

DDR2_HUMAN
NC score	0.066691 (rank : 445)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	181	Target Neighborhood Hits	818	Shared Neighborhood Hits	31
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

FAK2_MOUSE
NC score	0.066661 (rank : 446)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	181	Target Neighborhood Hits	851	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

TNK1_MOUSE
NC score	0.066607 (rank : 447)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	181	Target Neighborhood Hits	806	Shared Neighborhood Hits	33
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

FAK1_MOUSE
NC score	0.066592 (rank : 448)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	181	Target Neighborhood Hits	850	Shared Neighborhood Hits	31
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

ZAP70_MOUSE
NC score	0.066537 (rank : 449)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	181	Target Neighborhood Hits	905	Shared Neighborhood Hits	31
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_HUMAN
NC score	0.066492 (rank : 450)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	181	Target Neighborhood Hits	893	Shared Neighborhood Hits	31
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

DDR2_MOUSE
NC score	0.066205 (rank : 451)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	181	Target Neighborhood Hits	813	Shared Neighborhood Hits	31
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

ERBB2_HUMAN
NC score	0.066075 (rank : 452)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	181	Target Neighborhood Hits	1073	Shared Neighborhood Hits	37
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

FLT3_HUMAN
NC score	0.065974 (rank : 453)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	181	Target Neighborhood Hits	843	Shared Neighborhood Hits	45
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

ERBB4_HUMAN
NC score	0.065749 (rank : 454)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	181	Target Neighborhood Hits	910	Shared Neighborhood Hits	34
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

PECA1_MOUSE
NC score	0.065695 (rank : 455)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	181	Target Neighborhood Hits	126	Shared Neighborhood Hits	32
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

ERBB2_MOUSE
NC score	0.065471 (rank : 456)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	181	Target Neighborhood Hits	918	Shared Neighborhood Hits	32
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

EGFR_MOUSE
NC score	0.065452 (rank : 457)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	181	Target Neighborhood Hits	927	Shared Neighborhood Hits	34
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

ACK1_HUMAN
NC score	0.065447 (rank : 458)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	181	Target Neighborhood Hits	1140	Shared Neighborhood Hits	37
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
NC score	0.065359 (rank : 459)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	181	Target Neighborhood Hits	1080	Shared Neighborhood Hits	35
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

EGFR_HUMAN
NC score	0.065028 (rank : 460)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	181	Target Neighborhood Hits	939	Shared Neighborhood Hits	32
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

STYK1_MOUSE
NC score	0.064943 (rank : 461)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	181	Target Neighborhood Hits	779	Shared Neighborhood Hits	32
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

ERBB3_HUMAN
NC score	0.064496 (rank : 462)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	181	Target Neighborhood Hits	918	Shared Neighborhood Hits	32
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

LRC4B_MOUSE
NC score	0.064389 (rank : 463)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	181	Target Neighborhood Hits	484	Shared Neighborhood Hits	58
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

KSYK_HUMAN
NC score	0.064386 (rank : 464)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	181	Target Neighborhood Hits	901	Shared Neighborhood Hits	31
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

MET_MOUSE
NC score	0.064382 (rank : 465)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	181	Target Neighborhood Hits	844	Shared Neighborhood Hits	31
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

KSYK_MOUSE
NC score	0.064226 (rank : 466)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	181	Target Neighborhood Hits	944	Shared Neighborhood Hits	31
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

MET_HUMAN
NC score	0.064217 (rank : 467)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	181	Target Neighborhood Hits	831	Shared Neighborhood Hits	30
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

STYK1_HUMAN
NC score	0.063360 (rank : 468)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	181	Target Neighborhood Hits	786	Shared Neighborhood Hits	31
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

LRC4B_HUMAN
NC score	0.063184 (rank : 469)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	181	Target Neighborhood Hits	479	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

ERBB3_MOUSE
NC score	0.062797 (rank : 470)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	181	Target Neighborhood Hits	898	Shared Neighborhood Hits	31
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

RON_MOUSE
NC score	0.062778 (rank : 471)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	181	Target Neighborhood Hits	836	Shared Neighborhood Hits	30
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

SRMS_HUMAN
NC score	0.061946 (rank : 472)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	181	Target Neighborhood Hits	946	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

FES_MOUSE
NC score	0.061676 (rank : 473)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	181	Target Neighborhood Hits	980	Shared Neighborhood Hits	31
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_HUMAN
NC score	0.061606 (rank : 474)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	181	Target Neighborhood Hits	978	Shared Neighborhood Hits	32
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

RET_MOUSE
NC score	0.061464 (rank : 475)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	181	Target Neighborhood Hits	884	Shared Neighborhood Hits	33
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RON_HUMAN
NC score	0.061373 (rank : 476)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	181	Target Neighborhood Hits	842	Shared Neighborhood Hits	30
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

NGL1_MOUSE
NC score	0.061279 (rank : 477)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	181	Target Neighborhood Hits	512	Shared Neighborhood Hits	55
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

PVRL1_HUMAN
NC score	0.061245 (rank : 478)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	181	Target Neighborhood Hits	219	Shared Neighborhood Hits	36
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

NGL1_HUMAN
NC score	0.061200 (rank : 479)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	181	Target Neighborhood Hits	511	Shared Neighborhood Hits	55
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

TXK_MOUSE
NC score	0.061095 (rank : 480)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	181	Target Neighborhood Hits	980	Shared Neighborhood Hits	31
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

RET_HUMAN
NC score	0.061066 (rank : 481)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	181	Target Neighborhood Hits	873	Shared Neighborhood Hits	31
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

ILRL2_HUMAN
NC score	0.061064 (rank : 482)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

HCK_MOUSE
NC score	0.060947 (rank : 483)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	181	Target Neighborhood Hits	1029	Shared Neighborhood Hits	31
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

PVR_HUMAN
NC score	0.060818 (rank : 484)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	181	Target Neighborhood Hits	195	Shared Neighborhood Hits	35
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

HCK_HUMAN
NC score	0.060673 (rank : 485)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	181	Target Neighborhood Hits	1035	Shared Neighborhood Hits	32
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

TXK_HUMAN
NC score	0.060576 (rank : 486)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	181	Target Neighborhood Hits	971	Shared Neighborhood Hits	31
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

SRMS_MOUSE
NC score	0.060530 (rank : 487)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	181	Target Neighborhood Hits	964	Shared Neighborhood Hits	31
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

LCK_MOUSE
NC score	0.060383 (rank : 488)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	181	Target Neighborhood Hits	981	Shared Neighborhood Hits	31
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LCK_HUMAN
NC score	0.060265 (rank : 489)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	181	Target Neighborhood Hits	987	Shared Neighborhood Hits	33
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

FER_HUMAN
NC score	0.060245 (rank : 490)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	181	Target Neighborhood Hits	1278	Shared Neighborhood Hits	31
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

YES_HUMAN
NC score	0.060131 (rank : 491)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	181	Target Neighborhood Hits	1059	Shared Neighborhood Hits	32
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
NC score	0.060118 (rank : 492)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	181	Target Neighborhood Hits	1052	Shared Neighborhood Hits	31
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

BLK_MOUSE
NC score	0.059988 (rank : 493)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	181	Target Neighborhood Hits	992	Shared Neighborhood Hits	31
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

MATK_HUMAN
NC score	0.059897 (rank : 494)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	181	Target Neighborhood Hits	954	Shared Neighborhood Hits	31
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

PTN9_MOUSE
NC score	0.059803 (rank : 495)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	181	Target Neighborhood Hits	78	Shared Neighborhood Hits	9
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

ITK_MOUSE
NC score	0.059787 (rank : 496)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	181	Target Neighborhood Hits	985	Shared Neighborhood Hits	31
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

FCERA_HUMAN
NC score	0.059779 (rank : 497)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	38
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

ITK_HUMAN
NC score	0.059749 (rank : 498)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	181	Target Neighborhood Hits	1016	Shared Neighborhood Hits	31
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

PVRL1_MOUSE
NC score	0.059664 (rank : 499)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	181	Target Neighborhood Hits	201	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

PTN9_HUMAN
NC score	0.059616 (rank : 500)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	181	Target Neighborhood Hits	79	Shared Neighborhood Hits	9
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

FGR_MOUSE
NC score	0.059611 (rank : 501)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	181	Target Neighborhood Hits	1069	Shared Neighborhood Hits	31
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

TEC_MOUSE
NC score	0.059586 (rank : 502)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	181	Target Neighborhood Hits	1006	Shared Neighborhood Hits	31
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

MATK_MOUSE
NC score	0.059575 (rank : 503)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	181	Target Neighborhood Hits	952	Shared Neighborhood Hits	31
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

IL9R_HUMAN
NC score	0.059560 (rank : 504)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	181	Target Neighborhood Hits	35	Shared Neighborhood Hits	18
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

SRC_MOUSE
NC score	0.059544 (rank : 505)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	181	Target Neighborhood Hits	1033	Shared Neighborhood Hits	31
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

LYN_MOUSE
NC score	0.059521 (rank : 506)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	181	Target Neighborhood Hits	1023	Shared Neighborhood Hits	31
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

TEC_HUMAN
NC score	0.059499 (rank : 507)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	181	Target Neighborhood Hits	1006	Shared Neighborhood Hits	31
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

LYN_HUMAN
NC score	0.059449 (rank : 508)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	181	Target Neighborhood Hits	1022	Shared Neighborhood Hits	31
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

FGR_HUMAN
NC score	0.059389 (rank : 509)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	181	Target Neighborhood Hits	1067	Shared Neighborhood Hits	31
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

BLK_HUMAN
NC score	0.059365 (rank : 510)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	181	Target Neighborhood Hits	994	Shared Neighborhood Hits	31
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

PVRL3_HUMAN
NC score	0.059251 (rank : 511)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	181	Target Neighborhood Hits	204	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

BMX_MOUSE
NC score	0.059159 (rank : 512)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	181	Target Neighborhood Hits	912	Shared Neighborhood Hits	31
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

FRK_HUMAN
NC score	0.059100 (rank : 513)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	181	Target Neighborhood Hits	1058	Shared Neighborhood Hits	31
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

AATK_MOUSE
NC score	0.059059 (rank : 514)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	181	Target Neighborhood Hits	942	Shared Neighborhood Hits	32
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

SRC_HUMAN
NC score	0.059043 (rank : 515)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	181	Target Neighborhood Hits	1058	Shared Neighborhood Hits	31
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

BTK_HUMAN
NC score	0.059001 (rank : 516)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	181	Target Neighborhood Hits	1026	Shared Neighborhood Hits	31
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
NC score	0.058981 (rank : 517)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	181	Target Neighborhood Hits	1017	Shared Neighborhood Hits	31
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

ABL1_MOUSE
NC score	0.058956 (rank : 518)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	181	Target Neighborhood Hits	1178	Shared Neighborhood Hits	36
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

FYN_MOUSE
NC score	0.058921 (rank : 519)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	181	Target Neighborhood Hits	1073	Shared Neighborhood Hits	31
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

PTN7_HUMAN
NC score	0.058878 (rank : 520)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	181	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
NC score	0.058790 (rank : 521)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	181	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN5_HUMAN
NC score	0.058773 (rank : 522)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	181	Target Neighborhood Hits	80	Shared Neighborhood Hits	9
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

BMX_HUMAN
NC score	0.058637 (rank : 523)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	181	Target Neighborhood Hits	942	Shared Neighborhood Hits	31
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

PTN5_MOUSE
NC score	0.058590 (rank : 524)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	181	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

FYN_HUMAN
NC score	0.058490 (rank : 525)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	181	Target Neighborhood Hits	1078	Shared Neighborhood Hits	31
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

ABL2_HUMAN
NC score	0.058229 (rank : 526)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	181	Target Neighborhood Hits	1045	Shared Neighborhood Hits	31
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

PTN2_HUMAN
NC score	0.058194 (rank : 527)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	9
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

IRAK3_MOUSE
NC score	0.058138 (rank : 528)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	181	Target Neighborhood Hits	628	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK3_HUMAN
NC score	0.058110 (rank : 529)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	181	Target Neighborhood Hits	644	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

PTPRN_HUMAN
NC score	0.058047 (rank : 530)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	181	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPR2_MOUSE
NC score	0.058039 (rank : 531)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	181	Target Neighborhood Hits	120	Shared Neighborhood Hits	9
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTN2_MOUSE
NC score	0.057912 (rank : 532)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	181	Target Neighborhood Hits	107	Shared Neighborhood Hits	9
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTPR2_HUMAN
NC score	0.057846 (rank : 533)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	181	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

INAR1_HUMAN
NC score	0.057763 (rank : 534)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	181	Target Neighborhood Hits	49	Shared Neighborhood Hits	21
SwissProt Accessions	P17181, Q53GW9, Q53H11, Q8WTZ2	Gene names	IFNAR1, IFNAR
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

ABL1_HUMAN
NC score	0.057730 (rank : 535)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	181	Target Neighborhood Hits	1220	Shared Neighborhood Hits	31
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

PTPRR_MOUSE
NC score	0.057645 (rank : 536)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	181	Target Neighborhood Hits	84	Shared Neighborhood Hits	10
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

CSK_HUMAN
NC score	0.057600 (rank : 537)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	181	Target Neighborhood Hits	1009	Shared Neighborhood Hits	31
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

PTK6_MOUSE
NC score	0.057595 (rank : 538)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	181	Target Neighborhood Hits	1026	Shared Neighborhood Hits	31
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

AATK_HUMAN
NC score	0.057552 (rank : 539)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	181	Target Neighborhood Hits	1243	Shared Neighborhood Hits	37
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

LRC24_MOUSE
NC score	0.057530 (rank : 540)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	181	Target Neighborhood Hits	387	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

PTPRR_HUMAN
NC score	0.057443 (rank : 541)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	181	Target Neighborhood Hits	77	Shared Neighborhood Hits	9
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTN1_HUMAN
NC score	0.057374 (rank : 542)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	181	Target Neighborhood Hits	84	Shared Neighborhood Hits	9
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
NC score	0.057281 (rank : 543)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	181	Target Neighborhood Hits	85	Shared Neighborhood Hits	9
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
NC score	0.057149 (rank : 544)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	181	Target Neighborhood Hits	109	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

LRRC4_HUMAN
NC score	0.057130 (rank : 545)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	181	Target Neighborhood Hits	444	Shared Neighborhood Hits	54
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

PTPRN_MOUSE
NC score	0.057072 (rank : 546)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	181	Target Neighborhood Hits	240	Shared Neighborhood Hits	11
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

CSK_MOUSE
NC score	0.056651 (rank : 547)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	181	Target Neighborhood Hits	1009	Shared Neighborhood Hits	31
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

PTN18_MOUSE
NC score	0.056553 (rank : 548)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	181	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

FCGR1_HUMAN
NC score	0.056507 (rank : 549)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	181	Target Neighborhood Hits	145	Shared Neighborhood Hits	37
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

PTK6_HUMAN
NC score	0.056436 (rank : 550)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	181	Target Neighborhood Hits	1020	Shared Neighborhood Hits	31
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PGFRL_MOUSE
NC score	0.056409 (rank : 551)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	181	Target Neighborhood Hits	106	Shared Neighborhood Hits	35
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

JAK1_MOUSE
NC score	0.056269 (rank : 552)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	181	Target Neighborhood Hits	854	Shared Neighborhood Hits	31
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK1_HUMAN
NC score	0.056225 (rank : 553)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	181	Target Neighborhood Hits	858	Shared Neighborhood Hits	32
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

PTN18_HUMAN
NC score	0.056220 (rank : 554)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	181	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN22_MOUSE
NC score	0.055520 (rank : 555)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	181	Target Neighborhood Hits	179	Shared Neighborhood Hits	10
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN12_HUMAN
NC score	0.055508 (rank : 556)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

CT075_MOUSE
NC score	0.055136 (rank : 557)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	181	Target Neighborhood Hits	358	Shared Neighborhood Hits	46
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

PTN12_MOUSE
NC score	0.055080 (rank : 558)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	181	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

GUC2C_HUMAN
NC score	0.054924 (rank : 559)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	181	Target Neighborhood Hits	624	Shared Neighborhood Hits	27
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

JAK2_HUMAN
NC score	0.054607 (rank : 560)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	181	Target Neighborhood Hits	847	Shared Neighborhood Hits	31
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

GUC2F_HUMAN
NC score	0.054595 (rank : 561)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	181	Target Neighborhood Hits	740	Shared Neighborhood Hits	31
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

JAK2_MOUSE
NC score	0.053922 (rank : 562)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	181	Target Neighborhood Hits	839	Shared Neighborhood Hits	31
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

LAG3_MOUSE
NC score	0.053824 (rank : 563)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	181	Target Neighborhood Hits	117	Shared Neighborhood Hits	25
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

TYK2_MOUSE
NC score	0.053770 (rank : 564)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	181	Target Neighborhood Hits	850	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

ILK_MOUSE
NC score	0.053724 (rank : 565)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	181	Target Neighborhood Hits	858	Shared Neighborhood Hits	31
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

JAK3_HUMAN
NC score	0.053591 (rank : 566)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	181	Target Neighborhood Hits	827	Shared Neighborhood Hits	31
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

ILK1_HUMAN
NC score	0.053544 (rank : 567)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	181	Target Neighborhood Hits	857	Shared Neighborhood Hits	31
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
NC score	0.053398 (rank : 568)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	181	Target Neighborhood Hits	848	Shared Neighborhood Hits	31
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

PTN6_MOUSE
NC score	0.053218 (rank : 569)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	181	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN6_HUMAN
NC score	0.053053 (rank : 570)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	181	Target Neighborhood Hits	234	Shared Neighborhood Hits	9
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

TYK2_HUMAN
NC score	0.052929 (rank : 571)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	181	Target Neighborhood Hits	841	Shared Neighborhood Hits	31
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

MLKL_HUMAN
NC score	0.052824 (rank : 572)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	181	Target Neighborhood Hits	600	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

RAF1_MOUSE
NC score	0.051860 (rank : 573)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	181	Target Neighborhood Hits	886	Shared Neighborhood Hits	31
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

ARAF_MOUSE
NC score	0.051789 (rank : 574)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	181	Target Neighborhood Hits	874	Shared Neighborhood Hits	31
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

RAF1_HUMAN
NC score	0.051601 (rank : 575)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	181	Target Neighborhood Hits	886	Shared Neighborhood Hits	31
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

JAK3_MOUSE
NC score	0.051561 (rank : 576)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	181	Target Neighborhood Hits	821	Shared Neighborhood Hits	31
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

PTN11_HUMAN
NC score	0.051477 (rank : 577)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.051473 (rank : 578)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

ARAF_HUMAN
NC score	0.051341 (rank : 579)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	181	Target Neighborhood Hits	924	Shared Neighborhood Hits	31
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

I10R2_HUMAN
NC score	0.050379 (rank : 580)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	Q08334, Q9BUU4	Gene names	IL10RB, CRFB4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

BRAF1_HUMAN
NC score	0.050317 (rank : 581)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	181	Target Neighborhood Hits	883	Shared Neighborhood Hits	31
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

RIPK3_HUMAN
NC score	0.050181 (rank : 582)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	181	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

I20RA_MOUSE
NC score	0.047746 (rank : 583)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	181	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PHB0, Q8BW64	Gene names	Il20ra
Domain Architecture	No domain graphic available
Description	Interleukin-20 receptor alpha chain precursor (IL-20R-alpha) (IL- 20R1).

UBP53_MOUSE
NC score	0.029514 (rank : 584)	θ value	0.125558 (rank : 133)
Query Neighborhood Hits	181	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

IF4G3_HUMAN
NC score	0.025311 (rank : 585)	θ value	1.06291 (rank : 153)
Query Neighborhood Hits	181	Target Neighborhood Hits	247	Shared Neighborhood Hits	6
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

CO5_MOUSE
NC score	0.020035 (rank : 586)	θ value	0.62314 (rank : 145)
Query Neighborhood Hits	181	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P06684	Gene names	C5, Hc
Domain Architecture
Description	Complement C5 precursor (Hemolytic complement) [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

CO5_HUMAN
NC score	0.019642 (rank : 587)	θ value	1.06291 (rank : 152)
Query Neighborhood Hits	181	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P01031	Gene names	C5
Domain Architecture
Description	Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain].

LRP1B_MOUSE
NC score	0.019204 (rank : 588)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	181	Target Neighborhood Hits	606	Shared Neighborhood Hits	21
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

RNH2A_HUMAN
NC score	0.017348 (rank : 589)	θ value	3.0926 (rank : 161)
Query Neighborhood Hits	181	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O75792, Q96F11	Gene names	RNASEH2A, RNASEHI, RNHIA
Domain Architecture
Description	Ribonuclease H2 subunit A (EC 3.1.26.4) (RNase H2 subunit A) (Ribonuclease HI subunit A) (Ribonuclease HI large subunit) (RNase HI large subunit) (RNase H(35)) (Aicardi-Goutieres syndrome 4 protein) (AGS4).

ALMS1_HUMAN
NC score	0.013584 (rank : 590)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	181	Target Neighborhood Hits	356	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

FSBP_MOUSE
NC score	0.012920 (rank : 591)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	181	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BKE5, Q8BJX8	Gene names	Fsbp
Domain Architecture	No domain graphic available
Description	Fibrinogen silencer-binding protein.

STB5L_HUMAN
NC score	0.012113 (rank : 592)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	181	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2K9, Q4G1B4, Q6PIC3	Gene names	STXBP5L, KIAA1006, LLGL4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

STB5L_MOUSE
NC score	0.011219 (rank : 593)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	181	Target Neighborhood Hits	138	Shared Neighborhood Hits	4
SwissProt Accessions	Q5DQR4, Q3TSM3, Q3UVG2, Q5DQR1, Q5DQR2, Q5DQR3, Q8BS52	Gene names	Stxbp5l, Llgl4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 5-like (Tomosyn-2) (Lethal(2) giant larvae protein homolog 4).

DEN2A_MOUSE
NC score	0.008016 (rank : 594)	θ value	5.27518 (rank : 168)
Query Neighborhood Hits	181	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C4S8, Q3TJU2, Q3TUG3, Q3UXA3	Gene names	Dennd2a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

DEN2A_HUMAN
NC score	0.007722 (rank : 595)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	181	Target Neighborhood Hits	83	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

S4A7_HUMAN
NC score	0.005455 (rank : 596)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	181	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6M7, O60350, Q6AHZ9, Q9HC88, Q9UIB9	Gene names	SLC4A7, BT, NBC2, NBC2B, NBC3, SBC2, SLC4A6
Domain Architecture	No domain graphic available
Description	Sodium bicarbonate cotransporter 3 (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7).

KIF17_HUMAN
NC score	0.002146 (rank : 597)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	181	Target Neighborhood Hits	365	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2E2, O95077, Q53YS6, Q5VWA9, Q6GSA8, Q8N411	Gene names	KIF17, KIAA1405, KIF3X
Domain Architecture
Description	Kinesin-like protein KIF17 (KIF3-related motor protein).

PXR_HUMAN
NC score	0.000824 (rank : 598)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	181	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

PCDGH_HUMAN
NC score	-0.001808 (rank : 599)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	181	Target Neighborhood Hits	164	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5G0, Q9Y5C6	Gene names	PCDHGB5
Domain Architecture
Description	Protocadherin gamma B5 precursor (PCDH-gamma-B5).

RL3R1_HUMAN
NC score	-0.003246 (rank : 600)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	181	Target Neighborhood Hits	507	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NSD7	Gene names	RXFP3, RLN3R1, SALPR
Domain Architecture
Description	Relaxin-3 receptor 1 (RLN3 receptor 1) (Relaxin family peptide receptor 3) (Somatostatin- and angiotensin-like peptide receptor) (G protein-coupled receptor SALPR) (GPCR135).

ZFY_HUMAN
NC score	-0.008019 (rank : 601)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	181	Target Neighborhood Hits	752	Shared Neighborhood Hits	2
SwissProt Accessions	P08048, Q14021, Q15558, Q96TF3	Gene names	ZFY
Domain Architecture
Description	Zinc finger Y-chromosomal protein.