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Network neighborhood for query Sequence : TPOR_MOUSE

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TPOR_MOUSE
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TPOR_HUMAN
θ value	0 (rank : 1)	NC score	0.977962 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

TPOR_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

EPOR_MOUSE
θ value	4.16044e-13 (rank : 3)	NC score	0.489189 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	52	Shared Neighborhood Hits	20
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

EPOR_HUMAN
θ value	9.26847e-13 (rank : 4)	NC score	0.484877 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	P19235, Q15443	Gene names	EPOR
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

CRLF1_HUMAN
θ value	4.76016e-09 (rank : 5)	NC score	0.373943 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	122	Shared Neighborhood Hits	34
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

CRLF1_MOUSE
θ value	2.36244e-08 (rank : 6)	NC score	0.368858 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	116	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

IL7RA_HUMAN
θ value	0.00035302 (rank : 7)	NC score	0.273739 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	P16871, Q6SV45, Q9UPC1	Gene names	IL7R
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen) (CDw127).

EPHAA_HUMAN
θ value	0.000602161 (rank : 8)	NC score	0.031329 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	960	Shared Neighborhood Hits	10
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

IL21R_HUMAN
θ value	0.000786445 (rank : 9)	NC score	0.280408 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

CNTFR_HUMAN
θ value	0.00175202 (rank : 10)	NC score	0.231171 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	21
SwissProt Accessions	P26992	Gene names	CNTFR
Domain Architecture
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

CNTFR_MOUSE
θ value	0.00175202 (rank : 11)	NC score	0.230819 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	O88507, Q80T01	Gene names	Cntfr
Domain Architecture	No domain graphic available
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

IL7RA_MOUSE
θ value	0.00228821 (rank : 12)	NC score	0.269302 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	34	Shared Neighborhood Hits	17
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

PRLR_HUMAN
θ value	0.0193708 (rank : 13)	NC score	0.229023 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	95	Shared Neighborhood Hits	26
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

IL21R_MOUSE
θ value	0.0252991 (rank : 14)	NC score	0.254619 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

IL2RG_MOUSE
θ value	0.0330416 (rank : 15)	NC score	0.164482 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL27B_HUMAN
θ value	0.0431538 (rank : 16)	NC score	0.203092 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

I12R2_HUMAN
θ value	0.0563607 (rank : 17)	NC score	0.152443 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	163	Shared Neighborhood Hits	26
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
θ value	0.0736092 (rank : 18)	NC score	0.147570 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	143	Shared Neighborhood Hits	31
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

IL3B2_MOUSE
θ value	0.0736092 (rank : 19)	NC score	0.164771 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	372	Shared Neighborhood Hits	24
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL3RB_HUMAN
θ value	0.0736092 (rank : 20)	NC score	0.194741 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

I11RA_MOUSE
θ value	0.0961366 (rank : 21)	NC score	0.175624 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	95	Shared Neighborhood Hits	21
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

I11RB_MOUSE
θ value	0.163984 (rank : 22)	NC score	0.174794 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

I11RA_HUMAN
θ value	0.279714 (rank : 23)	NC score	0.176031 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	138	Shared Neighborhood Hits	20
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

IL9R_MOUSE
θ value	0.279714 (rank : 24)	NC score	0.178110 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q01114	Gene names	Il9r
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

IL3RB_MOUSE
θ value	0.365318 (rank : 25)	NC score	0.151468 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	355	Shared Neighborhood Hits	21
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

GHR_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.139896 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

SOX18_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.021400 (rank : 60)
Query Neighborhood Hits	56	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

LEPR_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.165972 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

E2F2_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.020987 (rank : 61)
Query Neighborhood Hits	56	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

EPHB3_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.015529 (rank : 66)
Query Neighborhood Hits	56	Target Neighborhood Hits	996	Shared Neighborhood Hits	21
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

LEPR_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.164782 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	112	Shared Neighborhood Hits	28
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

FMN2_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.024022 (rank : 58)
Query Neighborhood Hits	56	Target Neighborhood Hits	349	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

RBM16_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.033191 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	300	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

FMN2_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.022535 (rank : 59)
Query Neighborhood Hits	56	Target Neighborhood Hits	484	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

UBP42_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.012042 (rank : 70)
Query Neighborhood Hits	56	Target Neighborhood Hits	445	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

PELP1_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.020707 (rank : 62)
Query Neighborhood Hits	56	Target Neighborhood Hits	709	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SORL_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.028439 (rank : 57)
Query Neighborhood Hits	56	Target Neighborhood Hits	440	Shared Neighborhood Hits	15
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

DYH5_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.010884 (rank : 72)
Query Neighborhood Hits	56	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

IL6RA_MOUSE
θ value	5.27518 (rank : 39)	NC score	0.150704 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	104	Shared Neighborhood Hits	21
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

SORL_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.029308 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	439	Shared Neighborhood Hits	18
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TXND2_HUMAN
θ value	5.27518 (rank : 41)	NC score	0.007661 (rank : 76)
Query Neighborhood Hits	56	Target Neighborhood Hits	793	Shared Neighborhood Hits	4
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CDON_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.010902 (rank : 71)
Query Neighborhood Hits	56	Target Neighborhood Hits	410	Shared Neighborhood Hits	12
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

COG3_MOUSE
θ value	6.88961 (rank : 43)	NC score	0.016097 (rank : 65)
Query Neighborhood Hits	56	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CI04	Gene names	Cog3
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 3.

I12R1_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.084980 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	78	Shared Neighborhood Hits	14
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

MK07_MOUSE
θ value	6.88961 (rank : 45)	NC score	0.001759 (rank : 78)
Query Neighborhood Hits	56	Target Neighborhood Hits	1054	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MUC2_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.007938 (rank : 75)
Query Neighborhood Hits	56	Target Neighborhood Hits	906	Shared Neighborhood Hits	6
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NOVA1_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.013895 (rank : 67)
Query Neighborhood Hits	56	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

PGBM_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.007173 (rank : 77)
Query Neighborhood Hits	56	Target Neighborhood Hits	1073	Shared Neighborhood Hits	17
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

AMPO_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.010812 (rank : 73)
Query Neighborhood Hits	56	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6M6, Q5T9B1, Q5T9B3, Q5T9B4, Q8WUL6, Q96M23, Q96SS1	Gene names	ONPEP, C9orf3
Domain Architecture	No domain graphic available
Description	Aminopeptidase O (EC 3.4.11.-) (AP-O).

CSF3R_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.099042 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	140	Shared Neighborhood Hits	25
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

IL5RA_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.107579 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q01344, Q6ISX9	Gene names	IL5RA, IL5R
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen) (CDw125).

PTPRS_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.012528 (rank : 69)
Query Neighborhood Hits	56	Target Neighborhood Hits	472	Shared Neighborhood Hits	18
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

SFR15_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.020218 (rank : 63)
Query Neighborhood Hits	56	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SPR2G_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.018775 (rank : 64)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SSPO_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.010041 (rank : 74)
Query Neighborhood Hits	56	Target Neighborhood Hits	800	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TIE1_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.012667 (rank : 68)
Query Neighborhood Hits	56	Target Neighborhood Hits	1266	Shared Neighborhood Hits	17
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CRLF2_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.057782 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HC73, Q9H5R3	Gene names	CRLF2, ILXR
Domain Architecture	No domain graphic available
Description	Cytokine receptor-like factor 2 precursor (Cytokine receptor-like 2) (CRL2) (IL-XR) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

CRLF2_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.051757 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CII9, Q9CRJ6, Q9JIE7, Q9JIQ7, Q9JJH8, Q9JMD5	Gene names	Crlf2, Crlm2, Tpte2, Tslpr
Domain Architecture
Description	Cytokine receptor-like factor 2 precursor (Type I cytokine receptor delta 1) (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

CSF3R_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.094363 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

GHR_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.066389 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	43	Shared Neighborhood Hits	11
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

I13R1_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.058485 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

I13R1_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.094366 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

I13R2_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.100582 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

I27RA_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.084274 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	55	Shared Neighborhood Hits	19
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

IL12B_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.051666 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

IL12B_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.062556 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

IL27B_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.148411 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

IL2RB_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.093713 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL2RB_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.070250 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL2RG_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.093207 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL5RA_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.055841 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

IL6RA_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.138345 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	96	Shared Neighborhood Hits	20
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

IL6RB_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.124964 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	181	Shared Neighborhood Hits	32
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.116713 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	168	Shared Neighborhood Hits	28
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

IL9R_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.124257 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

LIFR_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.069968 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	130	Shared Neighborhood Hits	22
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

LIFR_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.052622 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

PRLR_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.178875 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	82	Shared Neighborhood Hits	24
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

Hits sorted by NC score

TPOR_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

TPOR_HUMAN
NC score	0.977962 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

EPOR_MOUSE
NC score	0.489189 (rank : 3)	θ value	4.16044e-13 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	52	Shared Neighborhood Hits	20
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

EPOR_HUMAN
NC score	0.484877 (rank : 4)	θ value	9.26847e-13 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	P19235, Q15443	Gene names	EPOR
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

CRLF1_HUMAN
NC score	0.373943 (rank : 5)	θ value	4.76016e-09 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	122	Shared Neighborhood Hits	34
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

CRLF1_MOUSE
NC score	0.368858 (rank : 6)	θ value	2.36244e-08 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	116	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

IL21R_HUMAN
NC score	0.280408 (rank : 7)	θ value	0.000786445 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

IL7RA_HUMAN
NC score	0.273739 (rank : 8)	θ value	0.00035302 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	36	Shared Neighborhood Hits	20
SwissProt Accessions	P16871, Q6SV45, Q9UPC1	Gene names	IL7R
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen) (CDw127).

IL7RA_MOUSE
NC score	0.269302 (rank : 9)	θ value	0.00228821 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	34	Shared Neighborhood Hits	17
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

IL21R_MOUSE
NC score	0.254619 (rank : 10)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

CNTFR_HUMAN
NC score	0.231171 (rank : 11)	θ value	0.00175202 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	66	Shared Neighborhood Hits	21
SwissProt Accessions	P26992	Gene names	CNTFR
Domain Architecture
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

CNTFR_MOUSE
NC score	0.230819 (rank : 12)	θ value	0.00175202 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	O88507, Q80T01	Gene names	Cntfr
Domain Architecture	No domain graphic available
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

PRLR_HUMAN
NC score	0.229023 (rank : 13)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	95	Shared Neighborhood Hits	26
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

IL27B_HUMAN
NC score	0.203092 (rank : 14)	θ value	0.0431538 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

IL3RB_HUMAN
NC score	0.194741 (rank : 15)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	163	Shared Neighborhood Hits	23
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

PRLR_MOUSE
NC score	0.178875 (rank : 16)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	56	Target Neighborhood Hits	82	Shared Neighborhood Hits	24
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

IL9R_MOUSE
NC score	0.178110 (rank : 17)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q01114	Gene names	Il9r
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

I11RA_HUMAN
NC score	0.176031 (rank : 18)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	138	Shared Neighborhood Hits	20
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

I11RA_MOUSE
NC score	0.175624 (rank : 19)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	95	Shared Neighborhood Hits	21
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

I11RB_MOUSE
NC score	0.174794 (rank : 20)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

LEPR_MOUSE
NC score	0.165972 (rank : 21)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

LEPR_HUMAN
NC score	0.164782 (rank : 22)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	112	Shared Neighborhood Hits	28
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

IL3B2_MOUSE
NC score	0.164771 (rank : 23)	θ value	0.0736092 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	372	Shared Neighborhood Hits	24
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL2RG_MOUSE
NC score	0.164482 (rank : 24)	θ value	0.0330416 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

I12R2_HUMAN
NC score	0.152443 (rank : 25)	θ value	0.0563607 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	163	Shared Neighborhood Hits	26
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

IL3RB_MOUSE
NC score	0.151468 (rank : 26)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	355	Shared Neighborhood Hits	21
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

IL6RA_MOUSE
NC score	0.150704 (rank : 27)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	104	Shared Neighborhood Hits	21
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

IL27B_MOUSE
NC score	0.148411 (rank : 28)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	56	Target Neighborhood Hits	55	Shared Neighborhood Hits	20
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

I12R2_MOUSE
NC score	0.147570 (rank : 29)	θ value	0.0736092 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	143	Shared Neighborhood Hits	31
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

GHR_HUMAN
NC score	0.139896 (rank : 30)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

IL6RA_HUMAN
NC score	0.138345 (rank : 31)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	56	Target Neighborhood Hits	96	Shared Neighborhood Hits	20
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

IL6RB_HUMAN
NC score	0.124964 (rank : 32)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	56	Target Neighborhood Hits	181	Shared Neighborhood Hits	32
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL9R_HUMAN
NC score	0.124257 (rank : 33)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	56	Target Neighborhood Hits	35	Shared Neighborhood Hits	14
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

IL6RB_MOUSE
NC score	0.116713 (rank : 34)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	56	Target Neighborhood Hits	168	Shared Neighborhood Hits	28
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

IL5RA_HUMAN
NC score	0.107579 (rank : 35)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q01344, Q6ISX9	Gene names	IL5RA, IL5R
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen) (CDw125).

I13R2_HUMAN
NC score	0.100582 (rank : 36)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	56	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

CSF3R_HUMAN
NC score	0.099042 (rank : 37)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	140	Shared Neighborhood Hits	25
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

I13R1_MOUSE
NC score	0.094366 (rank : 38)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	56	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

CSF3R_MOUSE
NC score	0.094363 (rank : 39)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	56	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

IL2RB_HUMAN
NC score	0.093713 (rank : 40)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	56	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL2RG_HUMAN
NC score	0.093207 (rank : 41)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	56	Target Neighborhood Hits	34	Shared Neighborhood Hits	14
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

I12R1_HUMAN
NC score	0.084980 (rank : 42)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	78	Shared Neighborhood Hits	14
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

I27RA_MOUSE
NC score	0.084274 (rank : 43)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	56	Target Neighborhood Hits	55	Shared Neighborhood Hits	19
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

IL2RB_MOUSE
NC score	0.070250 (rank : 44)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	56	Target Neighborhood Hits	51	Shared Neighborhood Hits	15
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

LIFR_HUMAN
NC score	0.069968 (rank : 45)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	56	Target Neighborhood Hits	130	Shared Neighborhood Hits	22
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

GHR_MOUSE
NC score	0.066389 (rank : 46)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	56	Target Neighborhood Hits	43	Shared Neighborhood Hits	11
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

IL12B_MOUSE
NC score	0.062556 (rank : 47)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	56	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

I13R1_HUMAN
NC score	0.058485 (rank : 48)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	56	Target Neighborhood Hits	31	Shared Neighborhood Hits	11
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

CRLF2_HUMAN
NC score	0.057782 (rank : 49)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	56	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HC73, Q9H5R3	Gene names	CRLF2, ILXR
Domain Architecture	No domain graphic available
Description	Cytokine receptor-like factor 2 precursor (Cytokine receptor-like 2) (CRL2) (IL-XR) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

IL5RA_MOUSE
NC score	0.055841 (rank : 50)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	56	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

LIFR_MOUSE
NC score	0.052622 (rank : 51)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	56	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

CRLF2_MOUSE
NC score	0.051757 (rank : 52)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	56	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CII9, Q9CRJ6, Q9JIE7, Q9JIQ7, Q9JJH8, Q9JMD5	Gene names	Crlf2, Crlm2, Tpte2, Tslpr
Domain Architecture
Description	Cytokine receptor-like factor 2 precursor (Type I cytokine receptor delta 1) (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

IL12B_HUMAN
NC score	0.051666 (rank : 53)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	56	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

RBM16_HUMAN
NC score	0.033191 (rank : 54)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	300	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UPN6, Q5TBU6, Q9BQN8, Q9BX43	Gene names	RBM16, KIAA1116
Domain Architecture
Description	Putative RNA-binding protein 16 (RNA-binding motif protein 16).

EPHAA_HUMAN
NC score	0.031329 (rank : 55)	θ value	0.000602161 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	960	Shared Neighborhood Hits	10
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

SORL_MOUSE
NC score	0.029308 (rank : 56)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	439	Shared Neighborhood Hits	18
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SORL_HUMAN
NC score	0.028439 (rank : 57)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	440	Shared Neighborhood Hits	15
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

FMN2_MOUSE
NC score	0.024022 (rank : 58)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	349	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

FMN2_HUMAN
NC score	0.022535 (rank : 59)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	484	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

SOX18_HUMAN
NC score	0.021400 (rank : 60)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	P35713, Q9NPH8	Gene names	SOX18
Domain Architecture
Description	Transcription factor SOX-18.

E2F2_HUMAN
NC score	0.020987 (rank : 61)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q14209	Gene names	E2F2
Domain Architecture
Description	Transcription factor E2F2 (E2F-2).

PELP1_MOUSE
NC score	0.020707 (rank : 62)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	709	Shared Neighborhood Hits	10
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

SFR15_HUMAN
NC score	0.020218 (rank : 63)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

SPR2G_MOUSE
NC score	0.018775 (rank : 64)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

COG3_MOUSE
NC score	0.016097 (rank : 65)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CI04	Gene names	Cog3
Domain Architecture	No domain graphic available
Description	Conserved oligomeric Golgi complex component 3.

EPHB3_MOUSE
NC score	0.015529 (rank : 66)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	996	Shared Neighborhood Hits	21
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

NOVA1_HUMAN
NC score	0.013895 (rank : 67)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	P51513	Gene names	NOVA1
Domain Architecture
Description	RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1).

TIE1_MOUSE
NC score	0.012667 (rank : 68)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	1266	Shared Neighborhood Hits	17
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

PTPRS_HUMAN
NC score	0.012528 (rank : 69)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	472	Shared Neighborhood Hits	18
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

UBP42_HUMAN
NC score	0.012042 (rank : 70)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	445	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

CDON_MOUSE
NC score	0.010902 (rank : 71)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	410	Shared Neighborhood Hits	12
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

DYH5_MOUSE
NC score	0.010884 (rank : 72)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHE6, Q8BWG1	Gene names	Dnah5, Dnahc5
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (Mdnah5).

AMPO_HUMAN
NC score	0.010812 (rank : 73)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N6M6, Q5T9B1, Q5T9B3, Q5T9B4, Q8WUL6, Q96M23, Q96SS1	Gene names	ONPEP, C9orf3
Domain Architecture	No domain graphic available
Description	Aminopeptidase O (EC 3.4.11.-) (AP-O).

SSPO_MOUSE
NC score	0.010041 (rank : 74)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	800	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

MUC2_HUMAN
NC score	0.007938 (rank : 75)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	906	Shared Neighborhood Hits	6
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TXND2_HUMAN
NC score	0.007661 (rank : 76)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	793	Shared Neighborhood Hits	4
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

PGBM_MOUSE
NC score	0.007173 (rank : 77)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	1073	Shared Neighborhood Hits	17
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MK07_MOUSE
NC score	0.001759 (rank : 78)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	1054	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).