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Network neighborhood for query Sequence : IL12B_MOUSE

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IL12B_MOUSE
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IL12B_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

IL12B_HUMAN
θ value	2.28696e-120 (rank : 2)	NC score	0.964801 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

IL27B_HUMAN
θ value	1.80886e-08 (rank : 3)	NC score	0.447326 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	80	Shared Neighborhood Hits	19
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

CNTFR_MOUSE
θ value	1.99992e-07 (rank : 4)	NC score	0.453398 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	O88507, Q80T01	Gene names	Cntfr
Domain Architecture	No domain graphic available
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

CNTFR_HUMAN
θ value	3.41135e-07 (rank : 5)	NC score	0.451888 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	66	Shared Neighborhood Hits	19
SwissProt Accessions	P26992	Gene names	CNTFR
Domain Architecture
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

IL6RA_HUMAN
θ value	6.43352e-06 (rank : 6)	NC score	0.424813 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

IL6RA_MOUSE
θ value	3.19293e-05 (rank : 7)	NC score	0.417674 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

I11RA_HUMAN
θ value	0.000602161 (rank : 8)	NC score	0.356353 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	138	Shared Neighborhood Hits	26
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

IL27B_MOUSE
θ value	0.000602161 (rank : 9)	NC score	0.386331 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

I11RA_MOUSE
θ value	0.0431538 (rank : 10)	NC score	0.334632 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	95	Shared Neighborhood Hits	23
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

PTPRS_HUMAN
θ value	0.0563607 (rank : 11)	NC score	0.045294 (rank : 51)
Query Neighborhood Hits	43	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

TITIN_HUMAN
θ value	0.0961366 (rank : 12)	NC score	0.048648 (rank : 49)
Query Neighborhood Hits	43	Target Neighborhood Hits	2923	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

I11RB_MOUSE
θ value	0.125558 (rank : 13)	NC score	0.333719 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	101	Shared Neighborhood Hits	24
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

MUC18_MOUSE
θ value	0.21417 (rank : 14)	NC score	0.070049 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	292	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

AMGO1_MOUSE
θ value	0.365318 (rank : 15)	NC score	0.033258 (rank : 53)
Query Neighborhood Hits	43	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

OBSCN_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.040767 (rank : 52)
Query Neighborhood Hits	43	Target Neighborhood Hits	1931	Shared Neighborhood Hits	33
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PRD15_HUMAN
θ value	0.365318 (rank : 17)	NC score	0.005623 (rank : 62)
Query Neighborhood Hits	43	Target Neighborhood Hits	805	Shared Neighborhood Hits	3
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

PGBM_HUMAN
θ value	0.47712 (rank : 18)	NC score	0.054711 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	1113	Shared Neighborhood Hits	30
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

HMCN1_HUMAN
θ value	0.62314 (rank : 19)	NC score	0.050128 (rank : 48)
Query Neighborhood Hits	43	Target Neighborhood Hits	983	Shared Neighborhood Hits	34
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

PGBM_MOUSE
θ value	0.62314 (rank : 20)	NC score	0.052202 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	1073	Shared Neighborhood Hits	32
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

FCG3B_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.080094 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	67	Shared Neighborhood Hits	14
SwissProt Accessions	O75015	Gene names	FCGR3B, CD16B, FCG3, FCGR3, IGFR3
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor III-B precursor (IgG Fc receptor III-1) (Fc-gamma RIII-beta) (Fc-gamma RIIIb) (FcRIIIb) (Fc-gamma RIII) (FcRIII) (FcR-10) (CD16b antigen).

TPOR_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.074352 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	70	Shared Neighborhood Hits	16
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

FCG3A_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.075196 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	P08637	Gene names	FCGR3A, CD16A, FCG3, FCGR3, IGFR3
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor III-A precursor (IgG Fc receptor III-2) (Fc-gamma RIII-alpha) (Fc-gamma RIIIa) (FcRIIIa) (Fc-gamma RIII) (FcRIII) (FcR-10) (CD16a antigen).

FGFR2_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.018198 (rank : 57)
Query Neighborhood Hits	43	Target Neighborhood Hits	1062	Shared Neighborhood Hits	17
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

LEPR_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.110721 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

RAGE_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.057200 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

SDK1_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.051758 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	511	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

TIE1_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.017447 (rank : 58)
Query Neighborhood Hits	43	Target Neighborhood Hits	1266	Shared Neighborhood Hits	17
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CHL1_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.045504 (rank : 50)
Query Neighborhood Hits	43	Target Neighborhood Hits	413	Shared Neighborhood Hits	23
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

PTPRB_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.020720 (rank : 55)
Query Neighborhood Hits	43	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

FCG2B_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.071167 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	116	Shared Neighborhood Hits	15
SwissProt Accessions	P31994, O95649, Q53X85, Q5VXA9, Q8NIA1	Gene names	FCGR2B, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-b precursor (Fc-gamma RII-b) (FcRII-b) (IgG Fc receptor II-b) (Fc-gamma-RIIb) (CD32 antigen) (CDw32).

FCG2C_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.071308 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	118	Shared Neighborhood Hits	16
SwissProt Accessions	P31995, O00523, O00524, O00525	Gene names	FCGR2C, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-c precursor (Fc-gamma RII-c) (FcRII-c) (IgG Fc receptor II-c) (Fc-gamma-RIIc) (CD32 antigen) (CDw32).

LEPR_MOUSE
θ value	4.03905 (rank : 33)	NC score	0.134876 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

MEGF9_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.019401 (rank : 56)
Query Neighborhood Hits	43	Target Neighborhood Hits	557	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SN_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.062025 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	434	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

FGFR2_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.017372 (rank : 59)
Query Neighborhood Hits	43	Target Neighborhood Hits	1062	Shared Neighborhood Hits	17
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

PRLR_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.102638 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

SDK1_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.050949 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	495	Shared Neighborhood Hits	28
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

TIE1_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.016753 (rank : 60)
Query Neighborhood Hits	43	Target Neighborhood Hits	1241	Shared Neighborhood Hits	18
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CD7_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.028038 (rank : 54)
Query Neighborhood Hits	43	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	P50283	Gene names	Cd7
Domain Architecture
Description	T-cell antigen CD7 precursor.

TIE2_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.015112 (rank : 61)
Query Neighborhood Hits	43	Target Neighborhood Hits	1192	Shared Neighborhood Hits	19
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

FCG2A_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.061113 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	P12318	Gene names	FCGR2A, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-a precursor (Fc-gamma RII-a) (FcRII-a) (IgG Fc receptor II-a) (Fc-gamma-RIIa) (CD32 antigen) (CDw32).

FCGR1_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.052066 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	145	Shared Neighborhood Hits	16
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

CRLF1_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.134799 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	122	Shared Neighborhood Hits	17
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

CRLF1_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.133378 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	116	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CSF3R_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.057403 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	140	Shared Neighborhood Hits	17
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CSF3R_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.061255 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	104	Shared Neighborhood Hits	18
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

DSCAM_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.053363 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	524	Shared Neighborhood Hits	33
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.051454 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	589	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

FCRL5_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.050702 (rank : 47)
Query Neighborhood Hits	43	Target Neighborhood Hits	267	Shared Neighborhood Hits	20
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

GHR_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.050717 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	57	Shared Neighborhood Hits	12
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

GHR_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.060242 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

I12R2_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.072322 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.076974 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	143	Shared Neighborhood Hits	21
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

IL6RB_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.090859 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	181	Shared Neighborhood Hits	19
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.087444 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	168	Shared Neighborhood Hits	18
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

NPHN_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.053494 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	362	Shared Neighborhood Hits	29
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NPHN_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.051118 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	370	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

OBSL1_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.057352 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	354	Shared Neighborhood Hits	23
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

PRLR_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.112734 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

SN_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.055331 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	416	Shared Neighborhood Hits	27
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

TPOR_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.062556 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	56	Shared Neighborhood Hits	13
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

Hits sorted by NC score

IL12B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

IL12B_HUMAN
NC score	0.964801 (rank : 2)	θ value	2.28696e-120 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	51	Shared Neighborhood Hits	24
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

CNTFR_MOUSE
NC score	0.453398 (rank : 3)	θ value	1.99992e-07 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	O88507, Q80T01	Gene names	Cntfr
Domain Architecture	No domain graphic available
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

CNTFR_HUMAN
NC score	0.451888 (rank : 4)	θ value	3.41135e-07 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	66	Shared Neighborhood Hits	19
SwissProt Accessions	P26992	Gene names	CNTFR
Domain Architecture
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

IL27B_HUMAN
NC score	0.447326 (rank : 5)	θ value	1.80886e-08 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	80	Shared Neighborhood Hits	19
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

IL6RA_HUMAN
NC score	0.424813 (rank : 6)	θ value	6.43352e-06 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	96	Shared Neighborhood Hits	24
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

IL6RA_MOUSE
NC score	0.417674 (rank : 7)	θ value	3.19293e-05 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

IL27B_MOUSE
NC score	0.386331 (rank : 8)	θ value	0.000602161 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	55	Shared Neighborhood Hits	14
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

I11RA_HUMAN
NC score	0.356353 (rank : 9)	θ value	0.000602161 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	138	Shared Neighborhood Hits	26
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

I11RA_MOUSE
NC score	0.334632 (rank : 10)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	95	Shared Neighborhood Hits	23
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

I11RB_MOUSE
NC score	0.333719 (rank : 11)	θ value	0.125558 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	101	Shared Neighborhood Hits	24
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

LEPR_MOUSE
NC score	0.134876 (rank : 12)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	109	Shared Neighborhood Hits	18
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

CRLF1_HUMAN
NC score	0.134799 (rank : 13)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	122	Shared Neighborhood Hits	17
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

CRLF1_MOUSE
NC score	0.133378 (rank : 14)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	116	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

PRLR_HUMAN
NC score	0.112734 (rank : 15)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	43	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

LEPR_HUMAN
NC score	0.110721 (rank : 16)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

PRLR_MOUSE
NC score	0.102638 (rank : 17)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

IL6RB_HUMAN
NC score	0.090859 (rank : 18)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	43	Target Neighborhood Hits	181	Shared Neighborhood Hits	19
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
NC score	0.087444 (rank : 19)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	43	Target Neighborhood Hits	168	Shared Neighborhood Hits	18
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

FCG3B_HUMAN
NC score	0.080094 (rank : 20)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	67	Shared Neighborhood Hits	14
SwissProt Accessions	O75015	Gene names	FCGR3B, CD16B, FCG3, FCGR3, IGFR3
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor III-B precursor (IgG Fc receptor III-1) (Fc-gamma RIII-beta) (Fc-gamma RIIIb) (FcRIIIb) (Fc-gamma RIII) (FcRIII) (FcR-10) (CD16b antigen).

I12R2_MOUSE
NC score	0.076974 (rank : 21)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	43	Target Neighborhood Hits	143	Shared Neighborhood Hits	21
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

FCG3A_HUMAN
NC score	0.075196 (rank : 22)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	P08637	Gene names	FCGR3A, CD16A, FCG3, FCGR3, IGFR3
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor III-A precursor (IgG Fc receptor III-2) (Fc-gamma RIII-alpha) (Fc-gamma RIIIa) (FcRIIIa) (Fc-gamma RIII) (FcRIII) (FcR-10) (CD16a antigen).

TPOR_HUMAN
NC score	0.074352 (rank : 23)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	70	Shared Neighborhood Hits	16
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

I12R2_HUMAN
NC score	0.072322 (rank : 24)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	43	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

FCG2C_HUMAN
NC score	0.071308 (rank : 25)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	118	Shared Neighborhood Hits	16
SwissProt Accessions	P31995, O00523, O00524, O00525	Gene names	FCGR2C, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-c precursor (Fc-gamma RII-c) (FcRII-c) (IgG Fc receptor II-c) (Fc-gamma-RIIc) (CD32 antigen) (CDw32).

FCG2B_HUMAN
NC score	0.071167 (rank : 26)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	116	Shared Neighborhood Hits	15
SwissProt Accessions	P31994, O95649, Q53X85, Q5VXA9, Q8NIA1	Gene names	FCGR2B, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-b precursor (Fc-gamma RII-b) (FcRII-b) (IgG Fc receptor II-b) (Fc-gamma-RIIb) (CD32 antigen) (CDw32).

MUC18_MOUSE
NC score	0.070049 (rank : 27)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	292	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

TPOR_MOUSE
NC score	0.062556 (rank : 28)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	43	Target Neighborhood Hits	56	Shared Neighborhood Hits	13
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

SN_HUMAN
NC score	0.062025 (rank : 29)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	434	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

CSF3R_MOUSE
NC score	0.061255 (rank : 30)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	43	Target Neighborhood Hits	104	Shared Neighborhood Hits	18
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

FCG2A_HUMAN
NC score	0.061113 (rank : 31)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	P12318	Gene names	FCGR2A, CD32, FCG2, IGFR2
Domain Architecture
Description	Low affinity immunoglobulin gamma Fc region receptor II-a precursor (Fc-gamma RII-a) (FcRII-a) (IgG Fc receptor II-a) (Fc-gamma-RIIa) (CD32 antigen) (CDw32).

GHR_MOUSE
NC score	0.060242 (rank : 32)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

CSF3R_HUMAN
NC score	0.057403 (rank : 33)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	140	Shared Neighborhood Hits	17
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

OBSL1_HUMAN
NC score	0.057352 (rank : 34)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	43	Target Neighborhood Hits	354	Shared Neighborhood Hits	23
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

RAGE_HUMAN
NC score	0.057200 (rank : 35)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

SN_MOUSE
NC score	0.055331 (rank : 36)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	43	Target Neighborhood Hits	416	Shared Neighborhood Hits	27
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

PGBM_HUMAN
NC score	0.054711 (rank : 37)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	1113	Shared Neighborhood Hits	30
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NPHN_HUMAN
NC score	0.053494 (rank : 38)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	43	Target Neighborhood Hits	362	Shared Neighborhood Hits	29
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

DSCAM_HUMAN
NC score	0.053363 (rank : 39)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	43	Target Neighborhood Hits	524	Shared Neighborhood Hits	33
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

PGBM_MOUSE
NC score	0.052202 (rank : 40)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	1073	Shared Neighborhood Hits	32
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

FCGR1_HUMAN
NC score	0.052066 (rank : 41)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	145	Shared Neighborhood Hits	16
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

SDK1_HUMAN
NC score	0.051758 (rank : 42)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	511	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

DSCL1_HUMAN
NC score	0.051454 (rank : 43)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	43	Target Neighborhood Hits	589	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

NPHN_MOUSE
NC score	0.051118 (rank : 44)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	43	Target Neighborhood Hits	370	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

SDK1_MOUSE
NC score	0.050949 (rank : 45)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	495	Shared Neighborhood Hits	28
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

GHR_HUMAN
NC score	0.050717 (rank : 46)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	43	Target Neighborhood Hits	57	Shared Neighborhood Hits	12
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

FCRL5_HUMAN
NC score	0.050702 (rank : 47)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	43	Target Neighborhood Hits	267	Shared Neighborhood Hits	20
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

HMCN1_HUMAN
NC score	0.050128 (rank : 48)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	983	Shared Neighborhood Hits	34
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

TITIN_HUMAN
NC score	0.048648 (rank : 49)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	2923	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CHL1_HUMAN
NC score	0.045504 (rank : 50)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	413	Shared Neighborhood Hits	23
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

PTPRS_HUMAN
NC score	0.045294 (rank : 51)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

OBSCN_HUMAN
NC score	0.040767 (rank : 52)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	1931	Shared Neighborhood Hits	33
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

AMGO1_MOUSE
NC score	0.033258 (rank : 53)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

CD7_MOUSE
NC score	0.028038 (rank : 54)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	142	Shared Neighborhood Hits	5
SwissProt Accessions	P50283	Gene names	Cd7
Domain Architecture
Description	T-cell antigen CD7 precursor.

PTPRB_HUMAN
NC score	0.020720 (rank : 55)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

MEGF9_HUMAN
NC score	0.019401 (rank : 56)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	557	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

FGFR2_MOUSE
NC score	0.018198 (rank : 57)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	1062	Shared Neighborhood Hits	17
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

TIE1_MOUSE
NC score	0.017447 (rank : 58)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	1266	Shared Neighborhood Hits	17
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

FGFR2_HUMAN
NC score	0.017372 (rank : 59)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	1062	Shared Neighborhood Hits	17
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

TIE1_HUMAN
NC score	0.016753 (rank : 60)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	1241	Shared Neighborhood Hits	18
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
NC score	0.015112 (rank : 61)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	1192	Shared Neighborhood Hits	19
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

PRD15_HUMAN
NC score	0.005623 (rank : 62)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	805	Shared Neighborhood Hits	3
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).