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Network neighborhood for query Sequence : PRLR_MOUSE

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PRLR_MOUSE
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PRLR_HUMAN
θ value	0 (rank : 1)	NC score	0.966929 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

PRLR_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

GHR_MOUSE
θ value	6.37413e-38 (rank : 3)	NC score	0.661362 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

GHR_HUMAN
θ value	2.67802e-36 (rank : 4)	NC score	0.695108 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	57	Shared Neighborhood Hits	24
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

CRLF1_HUMAN
θ value	1.24688e-25 (rank : 5)	NC score	0.712356 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	122	Shared Neighborhood Hits	46
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

CRLF1_MOUSE
θ value	1.62847e-25 (rank : 6)	NC score	0.713747 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	116	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

IL6RB_HUMAN
θ value	1.24977e-17 (rank : 7)	NC score	0.523898 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	181	Shared Neighborhood Hits	52
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

IL6RB_MOUSE
θ value	1.29331e-14 (rank : 8)	NC score	0.517391 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	168	Shared Neighborhood Hits	49
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

I11RB_MOUSE
θ value	1.74796e-11 (rank : 9)	NC score	0.519742 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	101	Shared Neighborhood Hits	38
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

I11RA_MOUSE
θ value	2.28291e-11 (rank : 10)	NC score	0.517394 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	95	Shared Neighborhood Hits	37
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

CSF3R_MOUSE
θ value	3.89403e-11 (rank : 11)	NC score	0.494532 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	104	Shared Neighborhood Hits	39
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

I11RA_HUMAN
θ value	2.13673e-09 (rank : 12)	NC score	0.497971 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	138	Shared Neighborhood Hits	36
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

I13R1_HUMAN
θ value	2.13673e-09 (rank : 13)	NC score	0.422798 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

I13R2_HUMAN
θ value	1.38499e-08 (rank : 14)	NC score	0.472203 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

IL6RA_MOUSE
θ value	1.80886e-08 (rank : 15)	NC score	0.484104 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	104	Shared Neighborhood Hits	27
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

EPOR_HUMAN
θ value	5.26297e-08 (rank : 16)	NC score	0.334257 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	58	Shared Neighborhood Hits	26
SwissProt Accessions	P19235, Q15443	Gene names	EPOR
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

CNTFR_MOUSE
θ value	1.17247e-07 (rank : 17)	NC score	0.485509 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	74	Shared Neighborhood Hits	27
SwissProt Accessions	O88507, Q80T01	Gene names	Cntfr
Domain Architecture	No domain graphic available
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

EPOR_MOUSE
θ value	1.53129e-07 (rank : 18)	NC score	0.357364 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	52	Shared Neighborhood Hits	23
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

IL5RA_HUMAN
θ value	3.41135e-07 (rank : 19)	NC score	0.370078 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	Q01344, Q6ISX9	Gene names	IL5RA, IL5R
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen) (CDw125).

IL6RA_HUMAN
θ value	3.41135e-07 (rank : 20)	NC score	0.476359 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

CNTFR_HUMAN
θ value	4.45536e-07 (rank : 21)	NC score	0.483218 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	P26992	Gene names	CNTFR
Domain Architecture
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

CSF3R_HUMAN
θ value	4.45536e-07 (rank : 22)	NC score	0.463031 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	140	Shared Neighborhood Hits	41
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

LIFR_HUMAN
θ value	4.45536e-07 (rank : 23)	NC score	0.389041 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	130	Shared Neighborhood Hits	46
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

I13R1_MOUSE
θ value	7.59969e-07 (rank : 24)	NC score	0.437990 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	48	Shared Neighborhood Hits	27
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

IL5RA_MOUSE
θ value	1.09739e-05 (rank : 25)	NC score	0.331108 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

LEPR_MOUSE
θ value	3.19293e-05 (rank : 26)	NC score	0.422060 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	109	Shared Neighborhood Hits	47
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

I27RA_MOUSE
θ value	4.1701e-05 (rank : 27)	NC score	0.301443 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

LIFR_MOUSE
θ value	7.1131e-05 (rank : 28)	NC score	0.355961 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	127	Shared Neighborhood Hits	39
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

CSF2R_HUMAN
θ value	0.000121331 (rank : 29)	NC score	0.289219 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P15509, O00207, Q14429, Q14430, Q14431, Q16564	Gene names	CSF2RA, CSF2R
Domain Architecture	No domain graphic available
Description	Granulocyte-macrophage colony-stimulating factor receptor alpha chain precursor (GM-CSF-R-alpha) (GMR) (CD116 antigen) (CDw116).

I12R2_HUMAN
θ value	0.000158464 (rank : 30)	NC score	0.396888 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	163	Shared Neighborhood Hits	45
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
θ value	0.000786445 (rank : 31)	NC score	0.387601 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	143	Shared Neighborhood Hits	46
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

IL3RB_MOUSE
θ value	0.00228821 (rank : 32)	NC score	0.167832 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	355	Shared Neighborhood Hits	26
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

NEO1_MOUSE
θ value	0.00298849 (rank : 33)	NC score	0.084118 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	523	Shared Neighborhood Hits	42
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

IL3RA_HUMAN
θ value	0.00390308 (rank : 34)	NC score	0.197744 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P26951	Gene names	IL3RA, IL3R
Domain Architecture	No domain graphic available
Description	Interleukin-3 receptor alpha chain precursor (IL-3R-alpha) (CD123 antigen).

TITIN_HUMAN
θ value	0.00390308 (rank : 35)	NC score	0.058921 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	2923	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

LEPR_HUMAN
θ value	0.00665767 (rank : 36)	NC score	0.380269 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

IL7RA_HUMAN
θ value	0.0113563 (rank : 37)	NC score	0.260341 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	P16871, Q6SV45, Q9UPC1	Gene names	IL7R
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen) (CDw127).

CNOT4_MOUSE
θ value	0.0330416 (rank : 38)	NC score	0.051205 (rank : 101)
Query Neighborhood Hits	82	Target Neighborhood Hits	277	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

IL3B2_MOUSE
θ value	0.0736092 (rank : 39)	NC score	0.178438 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	372	Shared Neighborhood Hits	29
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

PTPRD_MOUSE
θ value	0.0736092 (rank : 40)	NC score	0.080094 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	46
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

SDK2_MOUSE
θ value	0.125558 (rank : 41)	NC score	0.100983 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	480	Shared Neighborhood Hits	42
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

EPHB1_HUMAN
θ value	0.21417 (rank : 42)	NC score	0.021346 (rank : 112)
Query Neighborhood Hits	82	Target Neighborhood Hits	988	Shared Neighborhood Hits	34
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

CLMN_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.020024 (rank : 114)
Query Neighborhood Hits	82	Target Neighborhood Hits	205	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

SDK2_HUMAN
θ value	0.365318 (rank : 44)	NC score	0.098077 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	495	Shared Neighborhood Hits	43
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

HAX1_MOUSE
θ value	0.62314 (rank : 45)	NC score	0.041812 (rank : 108)
Query Neighborhood Hits	82	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	O35387	Gene names	Hax1, Hs1bp1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

SDK1_MOUSE
θ value	0.62314 (rank : 46)	NC score	0.089616 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	495	Shared Neighborhood Hits	42
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.087764 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	511	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

NACAM_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.016313 (rank : 119)
Query Neighborhood Hits	82	Target Neighborhood Hits	1866	Shared Neighborhood Hits	16
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

LR37A_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.016891 (rank : 117)
Query Neighborhood Hits	82	Target Neighborhood Hits	720	Shared Neighborhood Hits	7
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

TIE2_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.014976 (rank : 121)
Query Neighborhood Hits	82	Target Neighborhood Hits	1192	Shared Neighborhood Hits	33
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

IL3RB_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.177458 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

NPHN_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.054839 (rank : 91)
Query Neighborhood Hits	82	Target Neighborhood Hits	362	Shared Neighborhood Hits	26
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

EPHA5_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.022387 (rank : 111)
Query Neighborhood Hits	82	Target Neighborhood Hits	1009	Shared Neighborhood Hits	34
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

NOTC2_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.002536 (rank : 128)
Query Neighborhood Hits	82	Target Neighborhood Hits	1069	Shared Neighborhood Hits	8
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MYOM1_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.069843 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	415	Shared Neighborhood Hits	34
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

NFASC_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.051507 (rank : 99)
Query Neighborhood Hits	82	Target Neighborhood Hits	475	Shared Neighborhood Hits	33
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

ROBO2_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.054034 (rank : 93)
Query Neighborhood Hits	82	Target Neighborhood Hits	479	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO2_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.056362 (rank : 87)
Query Neighborhood Hits	82	Target Neighborhood Hits	504	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

SCG2_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.021293 (rank : 113)
Query Neighborhood Hits	82	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

WWP1_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.006590 (rank : 123)
Query Neighborhood Hits	82	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

MYBB_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.018532 (rank : 115)
Query Neighborhood Hits	82	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

PTPRM_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.043176 (rank : 106)
Query Neighborhood Hits	82	Target Neighborhood Hits	244	Shared Neighborhood Hits	27
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.042783 (rank : 107)
Query Neighborhood Hits	82	Target Neighborhood Hits	238	Shared Neighborhood Hits	27
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

SCUB3_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.004978 (rank : 125)
Query Neighborhood Hits	82	Target Neighborhood Hits	442	Shared Neighborhood Hits	6
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TPOR_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.177118 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

XAB2_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.024653 (rank : 109)
Query Neighborhood Hits	82	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DCD2, Q8VDT5, Q9CVD8	Gene names	Xab2
Domain Architecture
Description	XPA-binding protein 2.

CD45_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.016883 (rank : 118)
Query Neighborhood Hits	82	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CSF2R_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.119969 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q00941	Gene names	Csf2ra, Csfgmra
Domain Architecture	No domain graphic available
Description	Granulocyte-macrophage colony-stimulating factor receptor alpha chain precursor (GM-CSF-R-alpha) (GMR) (CD116 antigen).

GCR_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.004300 (rank : 126)
Query Neighborhood Hits	82	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

HA15_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.001305 (rank : 129)
Query Neighborhood Hits	82	Target Neighborhood Hits	209	Shared Neighborhood Hits	4
SwissProt Accessions	P06339	Gene names	H2-T23
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-37 alpha chain precursor.

IL12B_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.102638 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

IL7RA_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.160061 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

NCOA7_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.012024 (rank : 122)
Query Neighborhood Hits	82	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

XAB2_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.023413 (rank : 110)
Query Neighborhood Hits	82	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCS7, Q8TET6, Q96HB0, Q96IW0, Q9NRG6, Q9ULP3	Gene names	XAB2, HCNP, KIAA1177
Domain Architecture
Description	XPA-binding protein 2 (HCNP protein).

CNTN5_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.054852 (rank : 90)
Query Neighborhood Hits	82	Target Neighborhood Hits	446	Shared Neighborhood Hits	32
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

FINC_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.060568 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	302	Shared Neighborhood Hits	39
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.062703 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	309	Shared Neighborhood Hits	37
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

MYBB_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.016138 (rank : 120)
Query Neighborhood Hits	82	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P48972	Gene names	Mybl2, Bmyb
Domain Architecture
Description	Myb-related protein B (B-Myb).

CHD4_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.002605 (rank : 127)
Query Neighborhood Hits	82	Target Neighborhood Hits	365	Shared Neighborhood Hits	5
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CNTN5_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.055296 (rank : 88)
Query Neighborhood Hits	82	Target Neighborhood Hits	434	Shared Neighborhood Hits	32
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

IGF1R_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.006463 (rank : 124)
Query Neighborhood Hits	82	Target Neighborhood Hits	973	Shared Neighborhood Hits	23
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

MYLK_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.017302 (rank : 116)
Query Neighborhood Hits	82	Target Neighborhood Hits	1328	Shared Neighborhood Hits	26
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

CDON_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.050830 (rank : 103)
Query Neighborhood Hits	82	Target Neighborhood Hits	412	Shared Neighborhood Hits	31
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CDON_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.051392 (rank : 100)
Query Neighborhood Hits	82	Target Neighborhood Hits	410	Shared Neighborhood Hits	31
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CHL1_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.061633 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	413	Shared Neighborhood Hits	37
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

CHL1_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.057119 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	402	Shared Neighborhood Hits	33
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CNTN1_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.050598 (rank : 104)
Query Neighborhood Hits	82	Target Neighborhood Hits	431	Shared Neighborhood Hits	29
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CNTN2_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.051878 (rank : 97)
Query Neighborhood Hits	82	Target Neighborhood Hits	440	Shared Neighborhood Hits	33
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN3_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.066618 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	455	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN3_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.062669 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	447	Shared Neighborhood Hits	35
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN4_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.050239 (rank : 105)
Query Neighborhood Hits	82	Target Neighborhood Hits	449	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

COCA1_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.054415 (rank : 92)
Query Neighborhood Hits	82	Target Neighborhood Hits	458	Shared Neighborhood Hits	39
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.052390 (rank : 96)
Query Neighborhood Hits	82	Target Neighborhood Hits	467	Shared Neighborhood Hits	41
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

DCC_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.066359 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	583	Shared Neighborhood Hits	38
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.065726 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	896	Shared Neighborhood Hits	39
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DSCAM_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.069717 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	524	Shared Neighborhood Hits	40
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.074129 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	589	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

FNDC3_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.067473 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	196	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.063704 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	207	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

I12R1_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.056736 (rank : 86)
Query Neighborhood Hits	82	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

I27RA_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.227590 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	60	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

IL12B_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.123453 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

IL21R_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.120637 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

IL21R_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.121847 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

IL27B_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.347739 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

IL27B_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.342886 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

IL2RB_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.053328 (rank : 95)
Query Neighborhood Hits	82	Target Neighborhood Hits	54	Shared Neighborhood Hits	16
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL2RB_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.069513 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

IL2RG_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.150279 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	34	Shared Neighborhood Hits	17
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL2RG_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.141081 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL3RA_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.053638 (rank : 94)
Query Neighborhood Hits	82	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	P26952	Gene names	Il3ra, Sut-1
Domain Architecture	No domain graphic available
Description	Interleukin-3 receptor class 2 alpha chain precursor (Interleukin-3 receptor class II alpha chain) (CD123 antigen).

IL9R_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.073061 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

IL9R_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.081686 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q01114	Gene names	Il9r
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

L1CAM_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.058402 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	457	Shared Neighborhood Hits	35
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.060322 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	457	Shared Neighborhood Hits	37
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

MYOM1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.085716 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	405	Shared Neighborhood Hits	34
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

MYOM2_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.068965 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	341	Shared Neighborhood Hits	31
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

NEO1_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.077287 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	530	Shared Neighborhood Hits	42
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NPHN_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.051689 (rank : 98)
Query Neighborhood Hits	82	Target Neighborhood Hits	370	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NRCAM_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.072003 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	439	Shared Neighborhood Hits	37
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.062195 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	432	Shared Neighborhood Hits	33
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

PTPRD_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.076894 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	485	Shared Neighborhood Hits	44
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.062289 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	489	Shared Neighborhood Hits	38
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRS_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.059108 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	472	Shared Neighborhood Hits	38
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PUNC_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.051100 (rank : 102)
Query Neighborhood Hits	82	Target Neighborhood Hits	501	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO4_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.055257 (rank : 89)
Query Neighborhood Hits	82	Target Neighborhood Hits	364	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

TPOR_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.178875 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

USH2A_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.059752 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	600	Shared Neighborhood Hits	39
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.060759 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	626	Shared Neighborhood Hits	39
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

Hits sorted by NC score

PRLR_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

PRLR_HUMAN
NC score	0.966929 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	95	Shared Neighborhood Hits	51
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

CRLF1_MOUSE
NC score	0.713747 (rank : 3)	θ value	1.62847e-25 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	116	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CRLF1_HUMAN
NC score	0.712356 (rank : 4)	θ value	1.24688e-25 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	122	Shared Neighborhood Hits	46
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

GHR_HUMAN
NC score	0.695108 (rank : 5)	θ value	2.67802e-36 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	57	Shared Neighborhood Hits	24
SwissProt Accessions	P10912, Q9HCX2	Gene names	GHR
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

GHR_MOUSE
NC score	0.661362 (rank : 6)	θ value	6.37413e-38 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

IL6RB_HUMAN
NC score	0.523898 (rank : 7)	θ value	1.24977e-17 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	181	Shared Neighborhood Hits	52
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

I11RB_MOUSE
NC score	0.519742 (rank : 8)	θ value	1.74796e-11 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	101	Shared Neighborhood Hits	38
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

I11RA_MOUSE
NC score	0.517394 (rank : 9)	θ value	2.28291e-11 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	95	Shared Neighborhood Hits	37
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

IL6RB_MOUSE
NC score	0.517391 (rank : 10)	θ value	1.29331e-14 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	168	Shared Neighborhood Hits	49
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

I11RA_HUMAN
NC score	0.497971 (rank : 11)	θ value	2.13673e-09 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	138	Shared Neighborhood Hits	36
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

CSF3R_MOUSE
NC score	0.494532 (rank : 12)	θ value	3.89403e-11 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	104	Shared Neighborhood Hits	39
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

CNTFR_MOUSE
NC score	0.485509 (rank : 13)	θ value	1.17247e-07 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	74	Shared Neighborhood Hits	27
SwissProt Accessions	O88507, Q80T01	Gene names	Cntfr
Domain Architecture	No domain graphic available
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

IL6RA_MOUSE
NC score	0.484104 (rank : 14)	θ value	1.80886e-08 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	104	Shared Neighborhood Hits	27
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

CNTFR_HUMAN
NC score	0.483218 (rank : 15)	θ value	4.45536e-07 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	66	Shared Neighborhood Hits	27
SwissProt Accessions	P26992	Gene names	CNTFR
Domain Architecture
Description	Ciliary neurotrophic factor receptor alpha precursor (CNTFR alpha).

IL6RA_HUMAN
NC score	0.476359 (rank : 16)	θ value	3.41135e-07 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	96	Shared Neighborhood Hits	27
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

I13R2_HUMAN
NC score	0.472203 (rank : 17)	θ value	1.38499e-08 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	41	Shared Neighborhood Hits	30
SwissProt Accessions	Q14627, O00667	Gene names	IL13RA2, IL13R
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-2 chain precursor (Interleukin-13- binding protein) (CD213a2 antigen).

CSF3R_HUMAN
NC score	0.463031 (rank : 18)	θ value	4.45536e-07 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	140	Shared Neighborhood Hits	41
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

I13R1_MOUSE
NC score	0.437990 (rank : 19)	θ value	7.59969e-07 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	48	Shared Neighborhood Hits	27
SwissProt Accessions	O09030, Q7TT27	Gene names	Il13ra1, Il13r, Il13ra
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (Interleukin-13-binding protein) (NR4) (CD213a1 antigen).

I13R1_HUMAN
NC score	0.422798 (rank : 20)	θ value	2.13673e-09 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

LEPR_MOUSE
NC score	0.422060 (rank : 21)	θ value	3.19293e-05 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	109	Shared Neighborhood Hits	47
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

I12R2_HUMAN
NC score	0.396888 (rank : 22)	θ value	0.000158464 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	163	Shared Neighborhood Hits	45
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

LIFR_HUMAN
NC score	0.389041 (rank : 23)	θ value	4.45536e-07 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	130	Shared Neighborhood Hits	46
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

I12R2_MOUSE
NC score	0.387601 (rank : 24)	θ value	0.000786445 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	143	Shared Neighborhood Hits	46
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

LEPR_HUMAN
NC score	0.380269 (rank : 25)	θ value	0.00665767 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	112	Shared Neighborhood Hits	43
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

IL5RA_HUMAN
NC score	0.370078 (rank : 26)	θ value	3.41135e-07 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	44	Shared Neighborhood Hits	28
SwissProt Accessions	Q01344, Q6ISX9	Gene names	IL5RA, IL5R
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen) (CDw125).

EPOR_MOUSE
NC score	0.357364 (rank : 27)	θ value	1.53129e-07 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	52	Shared Neighborhood Hits	23
SwissProt Accessions	P14753, Q63852	Gene names	Epor
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

LIFR_MOUSE
NC score	0.355961 (rank : 28)	θ value	7.1131e-05 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	127	Shared Neighborhood Hits	39
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

IL27B_HUMAN
NC score	0.347739 (rank : 29)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	82	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

IL27B_MOUSE
NC score	0.342886 (rank : 30)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	82	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

EPOR_HUMAN
NC score	0.334257 (rank : 31)	θ value	5.26297e-08 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	58	Shared Neighborhood Hits	26
SwissProt Accessions	P19235, Q15443	Gene names	EPOR
Domain Architecture
Description	Erythropoietin receptor precursor (EPO-R).

IL5RA_MOUSE
NC score	0.331108 (rank : 32)	θ value	1.09739e-05 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	33	Shared Neighborhood Hits	23
SwissProt Accessions	P21183	Gene names	Il5ra, Il5r
Domain Architecture	No domain graphic available
Description	Interleukin-5 receptor alpha chain precursor (IL-5R-alpha) (CD125 antigen).

I27RA_MOUSE
NC score	0.301443 (rank : 33)	θ value	4.1701e-05 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

CSF2R_HUMAN
NC score	0.289219 (rank : 34)	θ value	0.000121331 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P15509, O00207, Q14429, Q14430, Q14431, Q16564	Gene names	CSF2RA, CSF2R
Domain Architecture	No domain graphic available
Description	Granulocyte-macrophage colony-stimulating factor receptor alpha chain precursor (GM-CSF-R-alpha) (GMR) (CD116 antigen) (CDw116).

IL7RA_HUMAN
NC score	0.260341 (rank : 35)	θ value	0.0113563 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	P16871, Q6SV45, Q9UPC1	Gene names	IL7R
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen) (CDw127).

I27RA_HUMAN
NC score	0.227590 (rank : 36)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	82	Target Neighborhood Hits	60	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

IL3RA_HUMAN
NC score	0.197744 (rank : 37)	θ value	0.00390308 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	21	Shared Neighborhood Hits	14
SwissProt Accessions	P26951	Gene names	IL3RA, IL3R
Domain Architecture	No domain graphic available
Description	Interleukin-3 receptor alpha chain precursor (IL-3R-alpha) (CD123 antigen).

TPOR_MOUSE
NC score	0.178875 (rank : 38)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	82	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q08351	Gene names	Mpl, Tpor
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

IL3B2_MOUSE
NC score	0.178438 (rank : 39)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	372	Shared Neighborhood Hits	29
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

IL3RB_HUMAN
NC score	0.177458 (rank : 40)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	163	Shared Neighborhood Hits	25
SwissProt Accessions	P32927	Gene names	CSF2RB, IL3RB, IL5RB
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131).

TPOR_HUMAN
NC score	0.177118 (rank : 41)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	P40238	Gene names	MPL, TPOR
Domain Architecture
Description	Thrombopoietin receptor precursor (TPO-R) (Myeloproliferative leukemia protein) (C-mpl) (CD110 antigen).

IL3RB_MOUSE
NC score	0.167832 (rank : 42)	θ value	0.00228821 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	355	Shared Neighborhood Hits	26
SwissProt Accessions	P26955	Gene names	Csf2rb, Aic2b, Csf2rb1, Il3rb1
Domain Architecture
Description	Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen).

IL7RA_MOUSE
NC score	0.160061 (rank : 43)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	P16872	Gene names	Il7r
Domain Architecture
Description	Interleukin-7 receptor alpha chain precursor (IL-7R-alpha) (CD127 antigen).

IL2RG_HUMAN
NC score	0.150279 (rank : 44)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	82	Target Neighborhood Hits	34	Shared Neighborhood Hits	17
SwissProt Accessions	P31785	Gene names	IL2RG
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL2RG_MOUSE
NC score	0.141081 (rank : 45)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	82	Target Neighborhood Hits	42	Shared Neighborhood Hits	20
SwissProt Accessions	P34902	Gene names	Il2rg
Domain Architecture
Description	Cytokine receptor common gamma chain precursor (Gamma-C) (Interleukin- 2 receptor gamma chain) (IL-2R gamma chain) (p64) (CD132 antigen).

IL12B_HUMAN
NC score	0.123453 (rank : 46)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	82	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P29460	Gene names	IL12B, NKSF2
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40) (NK cell stimulatory factor chain 2) (NKSF2).

IL21R_MOUSE
NC score	0.121847 (rank : 47)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	82	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

IL21R_HUMAN
NC score	0.120637 (rank : 48)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	82	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

CSF2R_MOUSE
NC score	0.119969 (rank : 49)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	24	Shared Neighborhood Hits	12
SwissProt Accessions	Q00941	Gene names	Csf2ra, Csfgmra
Domain Architecture	No domain graphic available
Description	Granulocyte-macrophage colony-stimulating factor receptor alpha chain precursor (GM-CSF-R-alpha) (GMR) (CD116 antigen).

IL12B_MOUSE
NC score	0.102638 (rank : 50)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	P43432, Q9QUM1	Gene names	Il12b
Domain Architecture
Description	Interleukin-12 beta chain precursor (IL-12B) (IL-12 p40) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (CLMF p40).

SDK2_MOUSE
NC score	0.100983 (rank : 51)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	480	Shared Neighborhood Hits	42
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_HUMAN
NC score	0.098077 (rank : 52)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	495	Shared Neighborhood Hits	43
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_MOUSE
NC score	0.089616 (rank : 53)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	495	Shared Neighborhood Hits	42
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_HUMAN
NC score	0.087764 (rank : 54)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	511	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

MYOM1_HUMAN
NC score	0.085716 (rank : 55)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	82	Target Neighborhood Hits	405	Shared Neighborhood Hits	34
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

NEO1_MOUSE
NC score	0.084118 (rank : 56)	θ value	0.00298849 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	523	Shared Neighborhood Hits	42
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

IL9R_MOUSE
NC score	0.081686 (rank : 57)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	82	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q01114	Gene names	Il9r
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

PTPRD_MOUSE
NC score	0.080094 (rank : 58)	θ value	0.0736092 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	46
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

NEO1_HUMAN
NC score	0.077287 (rank : 59)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	82	Target Neighborhood Hits	530	Shared Neighborhood Hits	42
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

PTPRD_HUMAN
NC score	0.076894 (rank : 60)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	82	Target Neighborhood Hits	485	Shared Neighborhood Hits	44
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

DSCL1_HUMAN
NC score	0.074129 (rank : 61)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	82	Target Neighborhood Hits	589	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

IL9R_HUMAN
NC score	0.073061 (rank : 62)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	82	Target Neighborhood Hits	35	Shared Neighborhood Hits	16
SwissProt Accessions	Q01113, Q14634, Q8WWU1, Q96TF0	Gene names	IL9R
Domain Architecture	No domain graphic available
Description	Interleukin-9 receptor precursor (IL-9R) (CD129 antigen).

NRCAM_HUMAN
NC score	0.072003 (rank : 63)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	82	Target Neighborhood Hits	439	Shared Neighborhood Hits	37
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

MYOM1_MOUSE
NC score	0.069843 (rank : 64)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	415	Shared Neighborhood Hits	34
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

DSCAM_HUMAN
NC score	0.069717 (rank : 65)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	82	Target Neighborhood Hits	524	Shared Neighborhood Hits	40
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

IL2RB_MOUSE
NC score	0.069513 (rank : 66)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	82	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	P16297, Q3TZT2	Gene names	Il2rb
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

MYOM2_HUMAN
NC score	0.068965 (rank : 67)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	82	Target Neighborhood Hits	341	Shared Neighborhood Hits	31
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

FNDC3_HUMAN
NC score	0.067473 (rank : 68)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	82	Target Neighborhood Hits	196	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

CNTN3_HUMAN
NC score	0.066618 (rank : 69)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	82	Target Neighborhood Hits	455	Shared Neighborhood Hits	37
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

DCC_HUMAN
NC score	0.066359 (rank : 70)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	82	Target Neighborhood Hits	583	Shared Neighborhood Hits	38
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
NC score	0.065726 (rank : 71)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	82	Target Neighborhood Hits	896	Shared Neighborhood Hits	39
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

FNDC3_MOUSE
NC score	0.063704 (rank : 72)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	82	Target Neighborhood Hits	207	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FINC_MOUSE
NC score	0.062703 (rank : 73)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	309	Shared Neighborhood Hits	37
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

CNTN3_MOUSE
NC score	0.062669 (rank : 74)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	82	Target Neighborhood Hits	447	Shared Neighborhood Hits	35
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

PTPRF_HUMAN
NC score	0.062289 (rank : 75)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	82	Target Neighborhood Hits	489	Shared Neighborhood Hits	38
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

NRCAM_MOUSE
NC score	0.062195 (rank : 76)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	82	Target Neighborhood Hits	432	Shared Neighborhood Hits	33
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

CHL1_HUMAN
NC score	0.061633 (rank : 77)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	413	Shared Neighborhood Hits	37
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

USH2A_MOUSE
NC score	0.060759 (rank : 78)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	82	Target Neighborhood Hits	626	Shared Neighborhood Hits	39
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

FINC_HUMAN
NC score	0.060568 (rank : 79)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	302	Shared Neighborhood Hits	39
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

L1CAM_MOUSE
NC score	0.060322 (rank : 80)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	82	Target Neighborhood Hits	457	Shared Neighborhood Hits	37
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

USH2A_HUMAN
NC score	0.059752 (rank : 81)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	82	Target Neighborhood Hits	600	Shared Neighborhood Hits	39
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

PTPRS_HUMAN
NC score	0.059108 (rank : 82)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	82	Target Neighborhood Hits	472	Shared Neighborhood Hits	38
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

TITIN_HUMAN
NC score	0.058921 (rank : 83)	θ value	0.00390308 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	2923	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

L1CAM_HUMAN
NC score	0.058402 (rank : 84)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	82	Target Neighborhood Hits	457	Shared Neighborhood Hits	35
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CHL1_MOUSE
NC score	0.057119 (rank : 85)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	82	Target Neighborhood Hits	402	Shared Neighborhood Hits	33
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

I12R1_HUMAN
NC score	0.056736 (rank : 86)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	82	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

ROBO2_MOUSE
NC score	0.056362 (rank : 87)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	504	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

CNTN5_MOUSE
NC score	0.055296 (rank : 88)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	434	Shared Neighborhood Hits	32
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

ROBO4_HUMAN
NC score	0.055257 (rank : 89)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	82	Target Neighborhood Hits	364	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

CNTN5_HUMAN
NC score	0.054852 (rank : 90)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	446	Shared Neighborhood Hits	32
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

NPHN_HUMAN
NC score	0.054839 (rank : 91)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	362	Shared Neighborhood Hits	26
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

COCA1_HUMAN
NC score	0.054415 (rank : 92)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	82	Target Neighborhood Hits	458	Shared Neighborhood Hits	39
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

ROBO2_HUMAN
NC score	0.054034 (rank : 93)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	479	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

IL3RA_MOUSE
NC score	0.053638 (rank : 94)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	82	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	P26952	Gene names	Il3ra, Sut-1
Domain Architecture	No domain graphic available
Description	Interleukin-3 receptor class 2 alpha chain precursor (Interleukin-3 receptor class II alpha chain) (CD123 antigen).

IL2RB_HUMAN
NC score	0.053328 (rank : 95)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	82	Target Neighborhood Hits	54	Shared Neighborhood Hits	16
SwissProt Accessions	P14784	Gene names	IL2RB
Domain Architecture
Description	Interleukin-2 receptor beta chain precursor (IL-2 receptor) (P70-75) (p75) (High affinity IL-2 receptor subunit beta) (CD122 antigen).

COCA1_MOUSE
NC score	0.052390 (rank : 96)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	82	Target Neighborhood Hits	467	Shared Neighborhood Hits	41
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

CNTN2_HUMAN
NC score	0.051878 (rank : 97)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	82	Target Neighborhood Hits	440	Shared Neighborhood Hits	33
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

NPHN_MOUSE
NC score	0.051689 (rank : 98)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	82	Target Neighborhood Hits	370	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

NFASC_MOUSE
NC score	0.051507 (rank : 99)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	475	Shared Neighborhood Hits	33
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

CDON_MOUSE
NC score	0.051392 (rank : 100)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	410	Shared Neighborhood Hits	31
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CNOT4_MOUSE
NC score	0.051205 (rank : 101)	θ value	0.0330416 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	277	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BT14, Q8CCR4, Q9CV74, Q9Z1D0	Gene names	Cnot4, Not4
Domain Architecture
Description	CCR4-NOT transcription complex subunit 4 (EC 6.3.2.-) (E3 ubiquitin protein ligase CNOT4) (CCR4-associated factor 4) (Potential transcriptional repressor NOT4Hp).

PUNC_MOUSE
NC score	0.051100 (rank : 102)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	82	Target Neighborhood Hits	501	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

CDON_HUMAN
NC score	0.050830 (rank : 103)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	412	Shared Neighborhood Hits	31
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CNTN1_HUMAN
NC score	0.050598 (rank : 104)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	82	Target Neighborhood Hits	431	Shared Neighborhood Hits	29
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CNTN4_HUMAN
NC score	0.050239 (rank : 105)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	82	Target Neighborhood Hits	449	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

PTPRM_HUMAN
NC score	0.043176 (rank : 106)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	244	Shared Neighborhood Hits	27
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
NC score	0.042783 (rank : 107)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	238	Shared Neighborhood Hits	27
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

HAX1_MOUSE
NC score	0.041812 (rank : 108)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	O35387	Gene names	Hax1, Hs1bp1
Domain Architecture	No domain graphic available
Description	HS1-associating protein X-1 (HAX-1) (HS1-binding protein).

XAB2_MOUSE
NC score	0.024653 (rank : 109)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DCD2, Q8VDT5, Q9CVD8	Gene names	Xab2
Domain Architecture
Description	XPA-binding protein 2.

XAB2_HUMAN
NC score	0.023413 (rank : 110)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCS7, Q8TET6, Q96HB0, Q96IW0, Q9NRG6, Q9ULP3	Gene names	XAB2, HCNP, KIAA1177
Domain Architecture
Description	XPA-binding protein 2 (HCNP protein).

EPHA5_HUMAN
NC score	0.022387 (rank : 111)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	1009	Shared Neighborhood Hits	34
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHB1_HUMAN
NC score	0.021346 (rank : 112)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	988	Shared Neighborhood Hits	34
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

SCG2_MOUSE
NC score	0.021293 (rank : 113)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q03517, Q80Y79, Q9CW80	Gene names	Scg2, Chgc, Scg-2
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

CLMN_HUMAN
NC score	0.020024 (rank : 114)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	205	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JQ2, Q9H713, Q9HA23, Q9HA57, Q9UFP4, Q9ULN2	Gene names	CLMN, KIAA1188
Domain Architecture
Description	Calmin.

MYBB_HUMAN
NC score	0.018532 (rank : 115)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

MYLK_HUMAN
NC score	0.017302 (rank : 116)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	1328	Shared Neighborhood Hits	26
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

LR37A_HUMAN
NC score	0.016891 (rank : 117)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	720	Shared Neighborhood Hits	7
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

CD45_HUMAN
NC score	0.016883 (rank : 118)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	243	Shared Neighborhood Hits	15
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

NACAM_MOUSE
NC score	0.016313 (rank : 119)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	1866	Shared Neighborhood Hits	16
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MYBB_MOUSE
NC score	0.016138 (rank : 120)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P48972	Gene names	Mybl2, Bmyb
Domain Architecture
Description	Myb-related protein B (B-Myb).

TIE2_HUMAN
NC score	0.014976 (rank : 121)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	1192	Shared Neighborhood Hits	33
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

NCOA7_HUMAN
NC score	0.012024 (rank : 122)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	160	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NI08, Q3LID6, Q4G0V1, Q5TF95, Q6IPQ4, Q6NE83, Q86T89, Q8N1W4	Gene names	NCOA7, ERAP140, ESNA1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1).

WWP1_MOUSE
NC score	0.006590 (rank : 123)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	138	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

IGF1R_MOUSE
NC score	0.006463 (rank : 124)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	973	Shared Neighborhood Hits	23
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

SCUB3_MOUSE
NC score	0.004978 (rank : 125)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	442	Shared Neighborhood Hits	6
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

GCR_MOUSE
NC score	0.004300 (rank : 126)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

CHD4_HUMAN
NC score	0.002605 (rank : 127)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	365	Shared Neighborhood Hits	5
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

NOTC2_MOUSE
NC score	0.002536 (rank : 128)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	1069	Shared Neighborhood Hits	8
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

HA15_MOUSE
NC score	0.001305 (rank : 129)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	209	Shared Neighborhood Hits	4
SwissProt Accessions	P06339	Gene names	H2-T23
Domain Architecture
Description	H-2 class I histocompatibility antigen, D-37 alpha chain precursor.