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Network neighborhood for query Sequence : USH2A_HUMAN

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USH2A_HUMAN
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

USH2A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	600	Target Neighborhood Hits	600	Shared Neighborhood Hits	600
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	0 (rank : 2)	NC score	0.979454 (rank : 2)
Query Neighborhood Hits	600	Target Neighborhood Hits	626	Shared Neighborhood Hits	444
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LAMA5_MOUSE
θ value	6.24247e-110 (rank : 3)	NC score	0.762848 (rank : 3)
Query Neighborhood Hits	600	Target Neighborhood Hits	828	Shared Neighborhood Hits	316
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_HUMAN
θ value	1.81628e-109 (rank : 4)	NC score	0.755775 (rank : 5)
Query Neighborhood Hits	600	Target Neighborhood Hits	976	Shared Neighborhood Hits	317
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA3_MOUSE
θ value	3.56116e-89 (rank : 5)	NC score	0.715353 (rank : 18)
Query Neighborhood Hits	600	Target Neighborhood Hits	859	Shared Neighborhood Hits	284
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMB3_HUMAN
θ value	1.35638e-80 (rank : 6)	NC score	0.753578 (rank : 6)
Query Neighborhood Hits	600	Target Neighborhood Hits	461	Shared Neighborhood Hits	196
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB1_MOUSE
θ value	3.69378e-78 (rank : 7)	NC score	0.710263 (rank : 22)
Query Neighborhood Hits	600	Target Neighborhood Hits	919	Shared Neighborhood Hits	254
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB3_MOUSE
θ value	3.82246e-75 (rank : 8)	NC score	0.760799 (rank : 4)
Query Neighborhood Hits	600	Target Neighborhood Hits	444	Shared Neighborhood Hits	218
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMB1_HUMAN
θ value	2.47765e-74 (rank : 9)	NC score	0.683380 (rank : 31)
Query Neighborhood Hits	600	Target Neighborhood Hits	1018	Shared Neighborhood Hits	257
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_MOUSE
θ value	3.23591e-74 (rank : 10)	NC score	0.746867 (rank : 10)
Query Neighborhood Hits	600	Target Neighborhood Hits	722	Shared Neighborhood Hits	278
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMA2_HUMAN
θ value	7.20884e-74 (rank : 11)	NC score	0.701250 (rank : 27)
Query Neighborhood Hits	600	Target Neighborhood Hits	1092	Shared Neighborhood Hits	314
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	1.22964e-73 (rank : 12)	NC score	0.676300 (rank : 32)
Query Neighborhood Hits	600	Target Neighborhood Hits	1198	Shared Neighborhood Hits	312
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB2_HUMAN
θ value	7.97034e-73 (rank : 13)	NC score	0.746357 (rank : 11)
Query Neighborhood Hits	600	Target Neighborhood Hits	692	Shared Neighborhood Hits	273
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMA1_MOUSE
θ value	1.50314e-71 (rank : 14)	NC score	0.741889 (rank : 12)
Query Neighborhood Hits	600	Target Neighborhood Hits	838	Shared Neighborhood Hits	313
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_HUMAN
θ value	1.66191e-70 (rank : 15)	NC score	0.749325 (rank : 9)
Query Neighborhood Hits	600	Target Neighborhood Hits	804	Shared Neighborhood Hits	318
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC1_HUMAN
θ value	1.2325e-65 (rank : 16)	NC score	0.683386 (rank : 30)
Query Neighborhood Hits	600	Target Neighborhood Hits	922	Shared Neighborhood Hits	270
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	8.83269e-64 (rank : 17)	NC score	0.703786 (rank : 26)
Query Neighborhood Hits	600	Target Neighborhood Hits	856	Shared Neighborhood Hits	272
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC3_MOUSE
θ value	2.17557e-62 (rank : 18)	NC score	0.749701 (rank : 8)
Query Neighborhood Hits	600	Target Neighborhood Hits	624	Shared Neighborhood Hits	274
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_HUMAN
θ value	1.19377e-60 (rank : 19)	NC score	0.751322 (rank : 7)
Query Neighborhood Hits	600	Target Neighborhood Hits	588	Shared Neighborhood Hits	283
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

NET1_MOUSE
θ value	8.57503e-51 (rank : 20)	NC score	0.705689 (rank : 25)
Query Neighborhood Hits	600	Target Neighborhood Hits	151	Shared Neighborhood Hits	126
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET4_HUMAN
θ value	3.2585e-50 (rank : 21)	NC score	0.730746 (rank : 14)
Query Neighborhood Hits	600	Target Neighborhood Hits	191	Shared Neighborhood Hits	163
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET1_HUMAN
θ value	7.25919e-50 (rank : 22)	NC score	0.706051 (rank : 24)
Query Neighborhood Hits	600	Target Neighborhood Hits	149	Shared Neighborhood Hits	125
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

SDK2_MOUSE
θ value	7.25919e-50 (rank : 23)	NC score	0.471751 (rank : 92)
Query Neighborhood Hits	600	Target Neighborhood Hits	480	Shared Neighborhood Hits	185
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_HUMAN
θ value	1.23823e-49 (rank : 24)	NC score	0.468003 (rank : 94)
Query Neighborhood Hits	600	Target Neighborhood Hits	495	Shared Neighborhood Hits	185
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

NET4_MOUSE
θ value	1.97686e-47 (rank : 25)	NC score	0.728201 (rank : 15)
Query Neighborhood Hits	600	Target Neighborhood Hits	180	Shared Neighborhood Hits	157
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

SDK1_HUMAN
θ value	3.37202e-47 (rank : 26)	NC score	0.463937 (rank : 98)
Query Neighborhood Hits	600	Target Neighborhood Hits	511	Shared Neighborhood Hits	183
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	7.51208e-47 (rank : 27)	NC score	0.466935 (rank : 95)
Query Neighborhood Hits	600	Target Neighborhood Hits	495	Shared Neighborhood Hits	184
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

NET2_MOUSE
θ value	6.15952e-41 (rank : 28)	NC score	0.720345 (rank : 16)
Query Neighborhood Hits	600	Target Neighborhood Hits	193	Shared Neighborhood Hits	160
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET2_HUMAN
θ value	5.21438e-40 (rank : 29)	NC score	0.718139 (rank : 17)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	153
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

MEGF9_HUMAN
θ value	6.81017e-40 (rank : 30)	NC score	0.738328 (rank : 13)
Query Neighborhood Hits	600	Target Neighborhood Hits	557	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	5.39604e-37 (rank : 31)	NC score	0.710472 (rank : 20)
Query Neighborhood Hits	600	Target Neighborhood Hits	896	Shared Neighborhood Hits	274
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PTPRD_HUMAN
θ value	1.01765e-35 (rank : 32)	NC score	0.405558 (rank : 121)
Query Neighborhood Hits	600	Target Neighborhood Hits	485	Shared Neighborhood Hits	195
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

MEGF6_HUMAN
θ value	1.6247e-33 (rank : 33)	NC score	0.569891 (rank : 48)
Query Neighborhood Hits	600	Target Neighborhood Hits	671	Shared Neighborhood Hits	305
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

PTPRF_HUMAN
θ value	7.54701e-31 (rank : 34)	NC score	0.396606 (rank : 128)
Query Neighborhood Hits	600	Target Neighborhood Hits	489	Shared Neighborhood Hits	188
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
θ value	6.38894e-30 (rank : 35)	NC score	0.401711 (rank : 122)
Query Neighborhood Hits	600	Target Neighborhood Hits	491	Shared Neighborhood Hits	189
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

NTNG1_HUMAN
θ value	2.42779e-29 (rank : 36)	NC score	0.710372 (rank : 21)
Query Neighborhood Hits	600	Target Neighborhood Hits	247	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	2.42779e-29 (rank : 37)	NC score	0.710106 (rank : 23)
Query Neighborhood Hits	600	Target Neighborhood Hits	246	Shared Neighborhood Hits	182
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NEO1_HUMAN
θ value	3.17079e-29 (rank : 38)	NC score	0.447290 (rank : 109)
Query Neighborhood Hits	600	Target Neighborhood Hits	530	Shared Neighborhood Hits	184
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NTNG2_HUMAN
θ value	5.40856e-29 (rank : 39)	NC score	0.711321 (rank : 19)
Query Neighborhood Hits	600	Target Neighborhood Hits	276	Shared Neighborhood Hits	188
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

SREC2_HUMAN
θ value	7.06379e-29 (rank : 40)	NC score	0.647502 (rank : 35)
Query Neighborhood Hits	600	Target Neighborhood Hits	645	Shared Neighborhood Hits	276
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

FNDC3_HUMAN
θ value	2.05525e-28 (rank : 41)	NC score	0.516939 (rank : 58)
Query Neighborhood Hits	600	Target Neighborhood Hits	196	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

NEO1_MOUSE
θ value	3.50572e-28 (rank : 42)	NC score	0.447587 (rank : 108)
Query Neighborhood Hits	600	Target Neighborhood Hits	523	Shared Neighborhood Hits	184
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

DSCAM_HUMAN
θ value	1.73987e-27 (rank : 43)	NC score	0.416455 (rank : 117)
Query Neighborhood Hits	600	Target Neighborhood Hits	524	Shared Neighborhood Hits	170
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

TITIN_HUMAN
θ value	2.27234e-27 (rank : 44)	NC score	0.232701 (rank : 348)
Query Neighborhood Hits	600	Target Neighborhood Hits	2923	Shared Neighborhood Hits	236
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SREC2_MOUSE
θ value	3.87602e-27 (rank : 45)	NC score	0.647650 (rank : 34)
Query Neighborhood Hits	600	Target Neighborhood Hits	605	Shared Neighborhood Hits	273
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

FNDC3_MOUSE
θ value	5.06226e-27 (rank : 46)	NC score	0.515133 (rank : 59)
Query Neighborhood Hits	600	Target Neighborhood Hits	207	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

SREC_HUMAN
θ value	5.59698e-26 (rank : 47)	NC score	0.637633 (rank : 37)
Query Neighborhood Hits	600	Target Neighborhood Hits	645	Shared Neighborhood Hits	279
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

FINC_HUMAN
θ value	2.77775e-25 (rank : 48)	NC score	0.458326 (rank : 101)
Query Neighborhood Hits	600	Target Neighborhood Hits	302	Shared Neighborhood Hits	198
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

DSCL1_HUMAN
θ value	3.62785e-25 (rank : 49)	NC score	0.420727 (rank : 116)
Query Neighborhood Hits	600	Target Neighborhood Hits	589	Shared Neighborhood Hits	176
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

DCC_HUMAN
θ value	6.18819e-25 (rank : 50)	NC score	0.434107 (rank : 113)
Query Neighborhood Hits	600	Target Neighborhood Hits	583	Shared Neighborhood Hits	187
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	8.08199e-25 (rank : 51)	NC score	0.423848 (rank : 115)
Query Neighborhood Hits	600	Target Neighborhood Hits	896	Shared Neighborhood Hits	197
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

PTPRS_HUMAN
θ value	1.05554e-24 (rank : 52)	NC score	0.390875 (rank : 134)
Query Neighborhood Hits	600	Target Neighborhood Hits	472	Shared Neighborhood Hits	185
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

FINC_MOUSE
θ value	3.07116e-24 (rank : 53)	NC score	0.460527 (rank : 100)
Query Neighborhood Hits	600	Target Neighborhood Hits	309	Shared Neighborhood Hits	194
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

LAMC2_MOUSE
θ value	4.01107e-24 (rank : 54)	NC score	0.686187 (rank : 29)
Query Neighborhood Hits	600	Target Neighborhood Hits	614	Shared Neighborhood Hits	270
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMA4_HUMAN
θ value	5.79196e-23 (rank : 55)	NC score	0.610658 (rank : 42)
Query Neighborhood Hits	600	Target Neighborhood Hits	708	Shared Neighborhood Hits	212
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMC2_HUMAN
θ value	9.87957e-23 (rank : 56)	NC score	0.661191 (rank : 33)
Query Neighborhood Hits	600	Target Neighborhood Hits	715	Shared Neighborhood Hits	264
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMA4_MOUSE
θ value	6.40375e-22 (rank : 57)	NC score	0.644226 (rank : 36)
Query Neighborhood Hits	600	Target Neighborhood Hits	584	Shared Neighborhood Hits	211
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

PGBM_HUMAN
θ value	6.40375e-22 (rank : 58)	NC score	0.628147 (rank : 40)
Query Neighborhood Hits	600	Target Neighborhood Hits	1113	Shared Neighborhood Hits	378
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	4.15078e-21 (rank : 59)	NC score	0.637152 (rank : 38)
Query Neighborhood Hits	600	Target Neighborhood Hits	1073	Shared Neighborhood Hits	375
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NOTC3_MOUSE
θ value	9.24701e-21 (rank : 60)	NC score	0.465021 (rank : 97)
Query Neighborhood Hits	600	Target Neighborhood Hits	975	Shared Neighborhood Hits	280
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
θ value	1.2077e-20 (rank : 61)	NC score	0.466021 (rank : 96)
Query Neighborhood Hits	600	Target Neighborhood Hits	1062	Shared Neighborhood Hits	293
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LAMA3_HUMAN
θ value	3.51386e-20 (rank : 62)	NC score	0.627536 (rank : 41)
Query Neighborhood Hits	600	Target Neighborhood Hits	760	Shared Neighborhood Hits	255
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

NOTC1_HUMAN
θ value	5.99374e-20 (rank : 63)	NC score	0.468292 (rank : 93)
Query Neighborhood Hits	600	Target Neighborhood Hits	906	Shared Neighborhood Hits	274
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

AGRIN_HUMAN
θ value	5.07402e-19 (rank : 64)	NC score	0.634670 (rank : 39)
Query Neighborhood Hits	600	Target Neighborhood Hits	582	Shared Neighborhood Hits	271
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

JAG1_MOUSE
θ value	6.62687e-19 (rank : 65)	NC score	0.520051 (rank : 54)
Query Neighborhood Hits	600	Target Neighborhood Hits	518	Shared Neighborhood Hits	266
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NOTC1_MOUSE
θ value	6.62687e-19 (rank : 66)	NC score	0.478617 (rank : 89)
Query Neighborhood Hits	600	Target Neighborhood Hits	916	Shared Neighborhood Hits	275
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
θ value	1.92812e-18 (rank : 67)	NC score	0.454790 (rank : 103)
Query Neighborhood Hits	600	Target Neighborhood Hits	1069	Shared Neighborhood Hits	280
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NRX3A_HUMAN
θ value	2.5182e-18 (rank : 68)	NC score	0.357661 (rank : 180)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

TENA_MOUSE
θ value	4.29542e-18 (rank : 69)	NC score	0.586185 (rank : 45)
Query Neighborhood Hits	600	Target Neighborhood Hits	596	Shared Neighborhood Hits	364
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

CNTN2_HUMAN
θ value	3.63628e-17 (rank : 70)	NC score	0.384890 (rank : 145)
Query Neighborhood Hits	600	Target Neighborhood Hits	440	Shared Neighborhood Hits	166
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

NRX1A_HUMAN
θ value	4.74913e-17 (rank : 71)	NC score	0.363845 (rank : 170)
Query Neighborhood Hits	600	Target Neighborhood Hits	170	Shared Neighborhood Hits	110
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

TENA_HUMAN
θ value	6.20254e-17 (rank : 72)	NC score	0.595849 (rank : 43)
Query Neighborhood Hits	600	Target Neighborhood Hits	631	Shared Neighborhood Hits	372
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

CNTP2_HUMAN
θ value	1.38178e-16 (rank : 73)	NC score	0.309693 (rank : 233)
Query Neighborhood Hits	600	Target Neighborhood Hits	199	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

NTNG2_MOUSE
θ value	2.35696e-16 (rank : 74)	NC score	0.689380 (rank : 28)
Query Neighborhood Hits	600	Target Neighborhood Hits	276	Shared Neighborhood Hits	190
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NRX2A_HUMAN
θ value	4.02038e-16 (rank : 75)	NC score	0.333038 (rank : 212)
Query Neighborhood Hits	600	Target Neighborhood Hits	614	Shared Neighborhood Hits	132
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

JAG2_MOUSE
θ value	8.95645e-16 (rank : 76)	NC score	0.511183 (rank : 61)
Query Neighborhood Hits	600	Target Neighborhood Hits	504	Shared Neighborhood Hits	257
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

CNTN2_MOUSE
θ value	1.16975e-15 (rank : 77)	NC score	0.381610 (rank : 147)
Query Neighborhood Hits	600	Target Neighborhood Hits	450	Shared Neighborhood Hits	162
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CELR2_HUMAN
θ value	1.99529e-15 (rank : 78)	NC score	0.320000 (rank : 225)
Query Neighborhood Hits	600	Target Neighborhood Hits	657	Shared Neighborhood Hits	247
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

NRX1A_MOUSE
θ value	1.99529e-15 (rank : 79)	NC score	0.359793 (rank : 173)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	109
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

CELR3_HUMAN
θ value	3.40345e-15 (rank : 80)	NC score	0.318443 (rank : 226)
Query Neighborhood Hits	600	Target Neighborhood Hits	680	Shared Neighborhood Hits	247
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

TENX_HUMAN
θ value	3.40345e-15 (rank : 81)	NC score	0.593914 (rank : 44)
Query Neighborhood Hits	600	Target Neighborhood Hits	789	Shared Neighborhood Hits	385
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

CELR1_HUMAN
θ value	5.8054e-15 (rank : 82)	NC score	0.310822 (rank : 230)
Query Neighborhood Hits	600	Target Neighborhood Hits	613	Shared Neighborhood Hits	231
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

NRCAM_HUMAN
θ value	5.8054e-15 (rank : 83)	NC score	0.415137 (rank : 118)
Query Neighborhood Hits	600	Target Neighborhood Hits	439	Shared Neighborhood Hits	168
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

CNTP2_MOUSE
θ value	1.29331e-14 (rank : 84)	NC score	0.309953 (rank : 231)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	120
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CELR3_MOUSE
θ value	1.68911e-14 (rank : 85)	NC score	0.317714 (rank : 227)
Query Neighborhood Hits	600	Target Neighborhood Hits	687	Shared Neighborhood Hits	250
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

JAG1_HUMAN
θ value	1.68911e-14 (rank : 86)	NC score	0.517139 (rank : 57)
Query Neighborhood Hits	600	Target Neighborhood Hits	514	Shared Neighborhood Hits	266
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG2_HUMAN
θ value	3.76295e-14 (rank : 87)	NC score	0.512297 (rank : 60)
Query Neighborhood Hits	600	Target Neighborhood Hits	491	Shared Neighborhood Hits	254
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NRCAM_MOUSE
θ value	8.38298e-14 (rank : 88)	NC score	0.406950 (rank : 119)
Query Neighborhood Hits	600	Target Neighborhood Hits	432	Shared Neighborhood Hits	166
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

NFASC_HUMAN
θ value	1.09485e-13 (rank : 89)	NC score	0.396721 (rank : 127)
Query Neighborhood Hits	600	Target Neighborhood Hits	497	Shared Neighborhood Hits	174
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

L1CAM_HUMAN
θ value	1.86753e-13 (rank : 90)	NC score	0.406819 (rank : 120)
Query Neighborhood Hits	600	Target Neighborhood Hits	457	Shared Neighborhood Hits	171
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

NOTC2_HUMAN
θ value	2.43908e-13 (rank : 91)	NC score	0.448848 (rank : 106)
Query Neighborhood Hits	600	Target Neighborhood Hits	1113	Shared Neighborhood Hits	290
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CELR2_MOUSE
θ value	3.18553e-13 (rank : 92)	NC score	0.305463 (rank : 242)
Query Neighborhood Hits	600	Target Neighborhood Hits	584	Shared Neighborhood Hits	226
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

L1CAM_MOUSE
θ value	5.43371e-13 (rank : 93)	NC score	0.399815 (rank : 124)
Query Neighborhood Hits	600	Target Neighborhood Hits	457	Shared Neighborhood Hits	173
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CELR1_MOUSE
θ value	9.26847e-13 (rank : 94)	NC score	0.308176 (rank : 237)
Query Neighborhood Hits	600	Target Neighborhood Hits	617	Shared Neighborhood Hits	240
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

TENR_MOUSE
θ value	2.0648e-12 (rank : 95)	NC score	0.520205 (rank : 53)
Query Neighborhood Hits	600	Target Neighborhood Hits	531	Shared Neighborhood Hits	347
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

DLL4_MOUSE
θ value	2.69671e-12 (rank : 96)	NC score	0.517857 (rank : 56)
Query Neighborhood Hits	600	Target Neighborhood Hits	440	Shared Neighborhood Hits	255
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC4_MOUSE
θ value	2.69671e-12 (rank : 97)	NC score	0.449921 (rank : 105)
Query Neighborhood Hits	600	Target Neighborhood Hits	872	Shared Neighborhood Hits	279
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ATRN_HUMAN
θ value	1.02475e-11 (rank : 98)	NC score	0.507136 (rank : 65)
Query Neighborhood Hits	600	Target Neighborhood Hits	525	Shared Neighborhood Hits	236
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

TENR_HUMAN
θ value	1.02475e-11 (rank : 99)	NC score	0.519966 (rank : 55)
Query Neighborhood Hits	600	Target Neighborhood Hits	526	Shared Neighborhood Hits	349
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ATRN_MOUSE
θ value	1.33837e-11 (rank : 100)	NC score	0.507925 (rank : 64)
Query Neighborhood Hits	600	Target Neighborhood Hits	519	Shared Neighborhood Hits	230
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CO7A1_HUMAN
θ value	1.33837e-11 (rank : 101)	NC score	0.246143 (rank : 324)
Query Neighborhood Hits	600	Target Neighborhood Hits	807	Shared Neighborhood Hits	173
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CNTP4_HUMAN
θ value	1.74796e-11 (rank : 102)	NC score	0.307694 (rank : 239)
Query Neighborhood Hits	600	Target Neighborhood Hits	187	Shared Neighborhood Hits	108
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

TENN_MOUSE
θ value	1.74796e-11 (rank : 103)	NC score	0.483132 (rank : 86)
Query Neighborhood Hits	600	Target Neighborhood Hits	484	Shared Neighborhood Hits	332
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CHL1_MOUSE
θ value	2.28291e-11 (rank : 104)	NC score	0.380065 (rank : 150)
Query Neighborhood Hits	600	Target Neighborhood Hits	402	Shared Neighborhood Hits	150
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CNTN4_MOUSE
θ value	2.28291e-11 (rank : 105)	NC score	0.364078 (rank : 168)
Query Neighborhood Hits	600	Target Neighborhood Hits	445	Shared Neighborhood Hits	150
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

NFASC_MOUSE
θ value	2.98157e-11 (rank : 106)	NC score	0.376568 (rank : 153)
Query Neighborhood Hits	600	Target Neighborhood Hits	475	Shared Neighborhood Hits	163
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

CNTN3_MOUSE
θ value	6.64225e-11 (rank : 107)	NC score	0.382684 (rank : 146)
Query Neighborhood Hits	600	Target Neighborhood Hits	447	Shared Neighborhood Hits	169
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN3_HUMAN
θ value	1.133e-10 (rank : 108)	NC score	0.381403 (rank : 148)
Query Neighborhood Hits	600	Target Neighborhood Hits	455	Shared Neighborhood Hits	170
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTP1_MOUSE
θ value	1.47974e-10 (rank : 109)	NC score	0.283910 (rank : 268)
Query Neighborhood Hits	600	Target Neighborhood Hits	183	Shared Neighborhood Hits	100
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTN4_HUMAN
θ value	3.29651e-10 (rank : 110)	NC score	0.363930 (rank : 169)
Query Neighborhood Hits	600	Target Neighborhood Hits	449	Shared Neighborhood Hits	150
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

DLL4_HUMAN
θ value	3.29651e-10 (rank : 111)	NC score	0.511095 (rank : 62)
Query Neighborhood Hits	600	Target Neighborhood Hits	435	Shared Neighborhood Hits	251
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC4_HUMAN
θ value	3.29651e-10 (rank : 112)	NC score	0.448252 (rank : 107)
Query Neighborhood Hits	600	Target Neighborhood Hits	905	Shared Neighborhood Hits	284
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

CNTP1_HUMAN
θ value	4.30538e-10 (rank : 113)	NC score	0.283698 (rank : 270)
Query Neighborhood Hits	600	Target Neighborhood Hits	196	Shared Neighborhood Hits	103
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

MEGF8_MOUSE
θ value	4.30538e-10 (rank : 114)	NC score	0.568686 (rank : 49)
Query Neighborhood Hits	600	Target Neighborhood Hits	520	Shared Neighborhood Hits	255
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

DLL1_HUMAN
θ value	5.62301e-10 (rank : 115)	NC score	0.506011 (rank : 66)
Query Neighborhood Hits	600	Target Neighborhood Hits	455	Shared Neighborhood Hits	256
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

MEGF8_HUMAN
θ value	5.62301e-10 (rank : 116)	NC score	0.577796 (rank : 47)
Query Neighborhood Hits	600	Target Neighborhood Hits	528	Shared Neighborhood Hits	260
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

STAB2_MOUSE
θ value	5.62301e-10 (rank : 117)	NC score	0.485047 (rank : 83)
Query Neighborhood Hits	600	Target Neighborhood Hits	528	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

COCA1_HUMAN
θ value	7.34386e-10 (rank : 118)	NC score	0.323011 (rank : 222)
Query Neighborhood Hits	600	Target Neighborhood Hits	458	Shared Neighborhood Hits	164
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

DLL1_MOUSE
θ value	9.59137e-10 (rank : 119)	NC score	0.503784 (rank : 67)
Query Neighborhood Hits	600	Target Neighborhood Hits	456	Shared Neighborhood Hits	261
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

I12R2_MOUSE
θ value	9.59137e-10 (rank : 120)	NC score	0.308291 (rank : 236)
Query Neighborhood Hits	600	Target Neighborhood Hits	143	Shared Neighborhood Hits	112
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

TIE2_HUMAN
θ value	1.25267e-09 (rank : 121)	NC score	0.274926 (rank : 284)
Query Neighborhood Hits	600	Target Neighborhood Hits	1192	Shared Neighborhood Hits	327
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

CHL1_HUMAN
θ value	1.63604e-09 (rank : 122)	NC score	0.387955 (rank : 141)
Query Neighborhood Hits	600	Target Neighborhood Hits	413	Shared Neighborhood Hits	154
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

CRUM2_HUMAN
θ value	1.63604e-09 (rank : 123)	NC score	0.498163 (rank : 76)
Query Neighborhood Hits	600	Target Neighborhood Hits	453	Shared Neighborhood Hits	252
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

STAB1_HUMAN
θ value	2.13673e-09 (rank : 124)	NC score	0.488208 (rank : 82)
Query Neighborhood Hits	600	Target Neighborhood Hits	546	Shared Neighborhood Hits	281
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TENN_HUMAN
θ value	2.13673e-09 (rank : 125)	NC score	0.461393 (rank : 99)
Query Neighborhood Hits	600	Target Neighborhood Hits	453	Shared Neighborhood Hits	315
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CNTN5_HUMAN
θ value	2.79066e-09 (rank : 126)	NC score	0.372894 (rank : 155)
Query Neighborhood Hits	600	Target Neighborhood Hits	446	Shared Neighborhood Hits	163
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

GPR98_HUMAN
θ value	2.79066e-09 (rank : 127)	NC score	0.111746 (rank : 648)
Query Neighborhood Hits	600	Target Neighborhood Hits	202	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

PTPRT_HUMAN
θ value	2.79066e-09 (rank : 128)	NC score	0.261961 (rank : 302)
Query Neighborhood Hits	600	Target Neighborhood Hits	217	Shared Neighborhood Hits	133
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	2.79066e-09 (rank : 129)	NC score	0.262365 (rank : 301)
Query Neighborhood Hits	600	Target Neighborhood Hits	219	Shared Neighborhood Hits	134
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

SORL_HUMAN
θ value	3.64472e-09 (rank : 130)	NC score	0.345958 (rank : 198)
Query Neighborhood Hits	600	Target Neighborhood Hits	440	Shared Neighborhood Hits	288
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

DNER_HUMAN
θ value	4.76016e-09 (rank : 131)	NC score	0.499546 (rank : 74)
Query Neighborhood Hits	600	Target Neighborhood Hits	460	Shared Neighborhood Hits	237
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

FRAS1_MOUSE
θ value	4.76016e-09 (rank : 132)	NC score	0.359259 (rank : 176)
Query Neighborhood Hits	600	Target Neighborhood Hits	747	Shared Neighborhood Hits	278
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PTPRK_MOUSE
θ value	4.76016e-09 (rank : 133)	NC score	0.243291 (rank : 330)
Query Neighborhood Hits	600	Target Neighborhood Hits	223	Shared Neighborhood Hits	128
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

STAB2_HUMAN
θ value	4.76016e-09 (rank : 134)	NC score	0.482987 (rank : 87)
Query Neighborhood Hits	600	Target Neighborhood Hits	534	Shared Neighborhood Hits	274
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

COCA1_MOUSE
θ value	6.21693e-09 (rank : 135)	NC score	0.330428 (rank : 214)
Query Neighborhood Hits	600	Target Neighborhood Hits	467	Shared Neighborhood Hits	172
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

PUNC_HUMAN
θ value	6.21693e-09 (rank : 136)	NC score	0.356310 (rank : 183)
Query Neighborhood Hits	600	Target Neighborhood Hits	449	Shared Neighborhood Hits	152
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

TIE2_MOUSE
θ value	6.21693e-09 (rank : 137)	NC score	0.278904 (rank : 278)
Query Neighborhood Hits	600	Target Neighborhood Hits	1204	Shared Neighborhood Hits	339
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

CNTN5_MOUSE
θ value	8.11959e-09 (rank : 138)	NC score	0.368136 (rank : 163)
Query Neighborhood Hits	600	Target Neighborhood Hits	434	Shared Neighborhood Hits	154
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

TIE1_MOUSE
θ value	8.11959e-09 (rank : 139)	NC score	0.292299 (rank : 259)
Query Neighborhood Hits	600	Target Neighborhood Hits	1266	Shared Neighborhood Hits	334
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

IL6RB_HUMAN
θ value	1.06045e-08 (rank : 140)	NC score	0.334045 (rank : 210)
Query Neighborhood Hits	600	Target Neighborhood Hits	181	Shared Neighborhood Hits	128
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

PTPRK_HUMAN
θ value	1.06045e-08 (rank : 141)	NC score	0.240741 (rank : 334)
Query Neighborhood Hits	600	Target Neighborhood Hits	228	Shared Neighborhood Hits	129
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

DNER_MOUSE
θ value	1.38499e-08 (rank : 142)	NC score	0.500016 (rank : 73)
Query Neighborhood Hits	600	Target Neighborhood Hits	413	Shared Neighborhood Hits	232
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

PCSK5_MOUSE
θ value	1.38499e-08 (rank : 143)	NC score	0.380372 (rank : 149)
Query Neighborhood Hits	600	Target Neighborhood Hits	613	Shared Neighborhood Hits	290
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PUNC_MOUSE
θ value	1.80886e-08 (rank : 144)	NC score	0.351405 (rank : 192)
Query Neighborhood Hits	600	Target Neighborhood Hits	501	Shared Neighborhood Hits	148
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

SCUB3_HUMAN
θ value	2.36244e-08 (rank : 145)	NC score	0.358334 (rank : 178)
Query Neighborhood Hits	600	Target Neighborhood Hits	428	Shared Neighborhood Hits	244
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

EPHA7_MOUSE
θ value	3.08544e-08 (rank : 146)	NC score	0.168363 (rank : 484)
Query Neighborhood Hits	600	Target Neighborhood Hits	1025	Shared Neighborhood Hits	211
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

CNTN1_MOUSE
θ value	4.0297e-08 (rank : 147)	NC score	0.370815 (rank : 158)
Query Neighborhood Hits	600	Target Neighborhood Hits	422	Shared Neighborhood Hits	153
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

EPHA7_HUMAN
θ value	4.0297e-08 (rank : 148)	NC score	0.178639 (rank : 455)
Query Neighborhood Hits	600	Target Neighborhood Hits	1053	Shared Neighborhood Hits	235
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

PTPRM_HUMAN
θ value	4.0297e-08 (rank : 149)	NC score	0.272911 (rank : 289)
Query Neighborhood Hits	600	Target Neighborhood Hits	244	Shared Neighborhood Hits	143
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	4.0297e-08 (rank : 150)	NC score	0.272285 (rank : 292)
Query Neighborhood Hits	600	Target Neighborhood Hits	238	Shared Neighborhood Hits	143
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRB_HUMAN
θ value	5.26297e-08 (rank : 151)	NC score	0.232067 (rank : 351)
Query Neighborhood Hits	600	Target Neighborhood Hits	242	Shared Neighborhood Hits	110
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

ITB4_HUMAN
θ value	6.87365e-08 (rank : 152)	NC score	0.580530 (rank : 46)
Query Neighborhood Hits	600	Target Neighborhood Hits	458	Shared Neighborhood Hits	336
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ROBO3_MOUSE
θ value	6.87365e-08 (rank : 153)	NC score	0.336937 (rank : 205)
Query Neighborhood Hits	600	Target Neighborhood Hits	524	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

CNTN1_HUMAN
θ value	8.97725e-08 (rank : 154)	NC score	0.369870 (rank : 161)
Query Neighborhood Hits	600	Target Neighborhood Hits	431	Shared Neighborhood Hits	152
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

COEA1_MOUSE
θ value	8.97725e-08 (rank : 155)	NC score	0.286852 (rank : 264)
Query Neighborhood Hits	600	Target Neighborhood Hits	402	Shared Neighborhood Hits	125
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

FRAS1_HUMAN
θ value	8.97725e-08 (rank : 156)	NC score	0.368014 (rank : 164)
Query Neighborhood Hits	600	Target Neighborhood Hits	759	Shared Neighborhood Hits	274
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LIFR_HUMAN
θ value	8.97725e-08 (rank : 157)	NC score	0.303067 (rank : 244)
Query Neighborhood Hits	600	Target Neighborhood Hits	130	Shared Neighborhood Hits	91
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

PTPRU_HUMAN
θ value	8.97725e-08 (rank : 158)	NC score	0.256619 (rank : 311)
Query Neighborhood Hits	600	Target Neighborhood Hits	237	Shared Neighborhood Hits	142
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

SLIT3_MOUSE
θ value	8.97725e-08 (rank : 159)	NC score	0.342933 (rank : 201)
Query Neighborhood Hits	600	Target Neighborhood Hits	700	Shared Neighborhood Hits	243
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TIE1_HUMAN
θ value	8.97725e-08 (rank : 160)	NC score	0.292714 (rank : 258)
Query Neighborhood Hits	600	Target Neighborhood Hits	1241	Shared Neighborhood Hits	334
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

EPHA3_MOUSE
θ value	1.53129e-07 (rank : 161)	NC score	0.169626 (rank : 478)
Query Neighborhood Hits	600	Target Neighborhood Hits	1009	Shared Neighborhood Hits	205
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

ROBO3_HUMAN
θ value	1.53129e-07 (rank : 162)	NC score	0.340704 (rank : 202)
Query Neighborhood Hits	600	Target Neighborhood Hits	570	Shared Neighborhood Hits	168
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

SLIT2_HUMAN
θ value	1.53129e-07 (rank : 163)	NC score	0.356235 (rank : 184)
Query Neighborhood Hits	600	Target Neighborhood Hits	708	Shared Neighborhood Hits	239
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

PTPRV_MOUSE
θ value	1.99992e-07 (rank : 164)	NC score	0.204858 (rank : 394)
Query Neighborhood Hits	600	Target Neighborhood Hits	179	Shared Neighborhood Hits	84
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

ROS_HUMAN
θ value	1.99992e-07 (rank : 165)	NC score	0.137290 (rank : 565)
Query Neighborhood Hits	600	Target Neighborhood Hits	907	Shared Neighborhood Hits	165
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

SCUB3_MOUSE
θ value	1.99992e-07 (rank : 166)	NC score	0.357121 (rank : 181)
Query Neighborhood Hits	600	Target Neighborhood Hits	442	Shared Neighborhood Hits	250
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SLIT1_MOUSE
θ value	1.99992e-07 (rank : 167)	NC score	0.361723 (rank : 171)
Query Neighborhood Hits	600	Target Neighborhood Hits	715	Shared Neighborhood Hits	245
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

EPHA8_HUMAN
θ value	2.61198e-07 (rank : 168)	NC score	0.154641 (rank : 522)
Query Neighborhood Hits	600	Target Neighborhood Hits	956	Shared Neighborhood Hits	167
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA8_MOUSE
θ value	2.61198e-07 (rank : 169)	NC score	0.157865 (rank : 514)
Query Neighborhood Hits	600	Target Neighborhood Hits	969	Shared Neighborhood Hits	173
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

GPR98_MOUSE
θ value	2.61198e-07 (rank : 170)	NC score	0.102557 (rank : 684)
Query Neighborhood Hits	600	Target Neighborhood Hits	206	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

EPHA3_HUMAN
θ value	3.41135e-07 (rank : 171)	NC score	0.164247 (rank : 499)
Query Neighborhood Hits	600	Target Neighborhood Hits	1005	Shared Neighborhood Hits	204
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHB3_MOUSE
θ value	3.41135e-07 (rank : 172)	NC score	0.158118 (rank : 513)
Query Neighborhood Hits	600	Target Neighborhood Hits	996	Shared Neighborhood Hits	187
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

CNTP4_MOUSE
θ value	4.45536e-07 (rank : 173)	NC score	0.299693 (rank : 248)
Query Neighborhood Hits	600	Target Neighborhood Hits	193	Shared Neighborhood Hits	120
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CRIM1_HUMAN
θ value	4.45536e-07 (rank : 174)	NC score	0.379594 (rank : 151)
Query Neighborhood Hits	600	Target Neighborhood Hits	362	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM1_HUMAN
θ value	4.45536e-07 (rank : 175)	NC score	0.500081 (rank : 72)
Query Neighborhood Hits	600	Target Neighborhood Hits	457	Shared Neighborhood Hits	245
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

INSR_MOUSE
θ value	4.45536e-07 (rank : 176)	NC score	0.127151 (rank : 596)
Query Neighborhood Hits	600	Target Neighborhood Hits	968	Shared Neighborhood Hits	164
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

STAB1_MOUSE
θ value	4.45536e-07 (rank : 177)	NC score	0.481076 (rank : 88)
Query Neighborhood Hits	600	Target Neighborhood Hits	566	Shared Neighborhood Hits	284
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

SLIT3_HUMAN
θ value	5.81887e-07 (rank : 178)	NC score	0.339441 (rank : 204)
Query Neighborhood Hits	600	Target Neighborhood Hits	682	Shared Neighborhood Hits	235
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

CNTN6_MOUSE
θ value	7.59969e-07 (rank : 179)	NC score	0.360843 (rank : 172)
Query Neighborhood Hits	600	Target Neighborhood Hits	429	Shared Neighborhood Hits	147
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

EPHA4_HUMAN
θ value	7.59969e-07 (rank : 180)	NC score	0.158938 (rank : 511)
Query Neighborhood Hits	600	Target Neighborhood Hits	975	Shared Neighborhood Hits	181
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

INSRR_MOUSE
θ value	7.59969e-07 (rank : 181)	NC score	0.143018 (rank : 554)
Query Neighborhood Hits	600	Target Neighborhood Hits	961	Shared Neighborhood Hits	186
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

ITB1_HUMAN
θ value	7.59969e-07 (rank : 182)	NC score	0.371507 (rank : 157)
Query Neighborhood Hits	600	Target Neighborhood Hits	298	Shared Neighborhood Hits	207
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

EPHA4_MOUSE
θ value	9.92553e-07 (rank : 183)	NC score	0.160170 (rank : 505)
Query Neighborhood Hits	600	Target Neighborhood Hits	982	Shared Neighborhood Hits	188
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA5_HUMAN
θ value	9.92553e-07 (rank : 184)	NC score	0.155329 (rank : 519)
Query Neighborhood Hits	600	Target Neighborhood Hits	1009	Shared Neighborhood Hits	188
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

INSRR_HUMAN
θ value	9.92553e-07 (rank : 185)	NC score	0.143610 (rank : 553)
Query Neighborhood Hits	600	Target Neighborhood Hits	950	Shared Neighborhood Hits	179
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

SORL_MOUSE
θ value	9.92553e-07 (rank : 186)	NC score	0.354705 (rank : 187)
Query Neighborhood Hits	600	Target Neighborhood Hits	439	Shared Neighborhood Hits	289
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

EPHB3_HUMAN
θ value	1.29631e-06 (rank : 187)	NC score	0.159775 (rank : 508)
Query Neighborhood Hits	600	Target Neighborhood Hits	996	Shared Neighborhood Hits	191
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

INSR_HUMAN
θ value	1.29631e-06 (rank : 188)	NC score	0.124880 (rank : 605)
Query Neighborhood Hits	600	Target Neighborhood Hits	963	Shared Neighborhood Hits	159
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

CDON_MOUSE
θ value	1.69304e-06 (rank : 189)	NC score	0.325260 (rank : 220)
Query Neighborhood Hits	600	Target Neighborhood Hits	410	Shared Neighborhood Hits	139
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CNTN6_HUMAN
θ value	1.69304e-06 (rank : 190)	NC score	0.366047 (rank : 166)
Query Neighborhood Hits	600	Target Neighborhood Hits	422	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

COEA1_HUMAN
θ value	1.69304e-06 (rank : 191)	NC score	0.259760 (rank : 307)
Query Neighborhood Hits	600	Target Neighborhood Hits	427	Shared Neighborhood Hits	139
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

I12R2_HUMAN
θ value	2.21117e-06 (rank : 192)	NC score	0.305630 (rank : 241)
Query Neighborhood Hits	600	Target Neighborhood Hits	163	Shared Neighborhood Hits	113
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

LRP1_HUMAN
θ value	2.21117e-06 (rank : 193)	NC score	0.351535 (rank : 191)
Query Neighborhood Hits	600	Target Neighborhood Hits	617	Shared Neighborhood Hits	278
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

ROBO2_MOUSE
θ value	2.21117e-06 (rank : 194)	NC score	0.336639 (rank : 206)
Query Neighborhood Hits	600	Target Neighborhood Hits	504	Shared Neighborhood Hits	166
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

EPHB1_HUMAN
θ value	2.88788e-06 (rank : 195)	NC score	0.150500 (rank : 533)
Query Neighborhood Hits	600	Target Neighborhood Hits	988	Shared Neighborhood Hits	196
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

LTBP4_MOUSE
θ value	2.88788e-06 (rank : 196)	NC score	0.398049 (rank : 125)
Query Neighborhood Hits	600	Target Neighborhood Hits	607	Shared Neighborhood Hits	259
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

CSF3R_HUMAN
θ value	3.77169e-06 (rank : 197)	NC score	0.273410 (rank : 286)
Query Neighborhood Hits	600	Target Neighborhood Hits	140	Shared Neighborhood Hits	103
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

ITB1_MOUSE
θ value	3.77169e-06 (rank : 198)	NC score	0.370559 (rank : 159)
Query Neighborhood Hits	600	Target Neighborhood Hits	283	Shared Neighborhood Hits	197
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

LTBP3_MOUSE
θ value	3.77169e-06 (rank : 199)	NC score	0.359279 (rank : 175)
Query Neighborhood Hits	600	Target Neighborhood Hits	475	Shared Neighborhood Hits	249
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MYOM1_HUMAN
θ value	3.77169e-06 (rank : 200)	NC score	0.374067 (rank : 154)
Query Neighborhood Hits	600	Target Neighborhood Hits	405	Shared Neighborhood Hits	162
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

CDON_HUMAN
θ value	4.92598e-06 (rank : 201)	NC score	0.328240 (rank : 217)
Query Neighborhood Hits	600	Target Neighborhood Hits	412	Shared Neighborhood Hits	144
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

IGF1R_HUMAN
θ value	4.92598e-06 (rank : 202)	NC score	0.124649 (rank : 607)
Query Neighborhood Hits	600	Target Neighborhood Hits	977	Shared Neighborhood Hits	174
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	4.92598e-06 (rank : 203)	NC score	0.125006 (rank : 603)
Query Neighborhood Hits	600	Target Neighborhood Hits	973	Shared Neighborhood Hits	176
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

LIFR_MOUSE
θ value	4.92598e-06 (rank : 204)	NC score	0.297480 (rank : 251)
Query Neighborhood Hits	600	Target Neighborhood Hits	127	Shared Neighborhood Hits	90
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

ROBO1_MOUSE
θ value	6.43352e-06 (rank : 205)	NC score	0.331404 (rank : 213)
Query Neighborhood Hits	600	Target Neighborhood Hits	559	Shared Neighborhood Hits	168
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

FBN2_HUMAN
θ value	8.40245e-06 (rank : 206)	NC score	0.387363 (rank : 142)
Query Neighborhood Hits	600	Target Neighborhood Hits	560	Shared Neighborhood Hits	275
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	8.40245e-06 (rank : 207)	NC score	0.385864 (rank : 144)
Query Neighborhood Hits	600	Target Neighborhood Hits	549	Shared Neighborhood Hits	276
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

DLK_HUMAN
θ value	1.09739e-05 (rank : 208)	NC score	0.510241 (rank : 63)
Query Neighborhood Hits	600	Target Neighborhood Hits	401	Shared Neighborhood Hits	249
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

FBN1_MOUSE
θ value	1.43324e-05 (rank : 209)	NC score	0.389954 (rank : 136)
Query Neighborhood Hits	600	Target Neighborhood Hits	563	Shared Neighborhood Hits	279
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP2_MOUSE
θ value	1.43324e-05 (rank : 210)	NC score	0.393016 (rank : 132)
Query Neighborhood Hits	600	Target Neighborhood Hits	617	Shared Neighborhood Hits	274
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CNTP3_HUMAN
θ value	1.87187e-05 (rank : 211)	NC score	0.280590 (rank : 275)
Query Neighborhood Hits	600	Target Neighborhood Hits	195	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

FBN1_HUMAN
θ value	1.87187e-05 (rank : 212)	NC score	0.388465 (rank : 139)
Query Neighborhood Hits	600	Target Neighborhood Hits	557	Shared Neighborhood Hits	283
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LRP1B_HUMAN
θ value	1.87187e-05 (rank : 213)	NC score	0.336520 (rank : 207)
Query Neighborhood Hits	600	Target Neighborhood Hits	602	Shared Neighborhood Hits	258
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KRA51_HUMAN
θ value	2.44474e-05 (rank : 214)	NC score	0.567188 (rank : 50)
Query Neighborhood Hits	600	Target Neighborhood Hits	288	Shared Neighborhood Hits	168
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

UROM_MOUSE
θ value	2.44474e-05 (rank : 215)	NC score	0.294158 (rank : 257)
Query Neighborhood Hits	600	Target Neighborhood Hits	276	Shared Neighborhood Hits	183
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ROBO2_HUMAN
θ value	3.19293e-05 (rank : 216)	NC score	0.336484 (rank : 208)
Query Neighborhood Hits	600	Target Neighborhood Hits	479	Shared Neighborhood Hits	164
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

CRUM1_MOUSE
θ value	4.1701e-05 (rank : 217)	NC score	0.499162 (rank : 75)
Query Neighborhood Hits	600	Target Neighborhood Hits	444	Shared Neighborhood Hits	241
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

FATH_HUMAN
θ value	4.1701e-05 (rank : 218)	NC score	0.258394 (rank : 309)
Query Neighborhood Hits	600	Target Neighborhood Hits	570	Shared Neighborhood Hits	233
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

LTB1L_MOUSE
θ value	4.1701e-05 (rank : 219)	NC score	0.347168 (rank : 196)
Query Neighborhood Hits	600	Target Neighborhood Hits	514	Shared Neighborhood Hits	246
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	4.1701e-05 (rank : 220)	NC score	0.347328 (rank : 195)
Query Neighborhood Hits	600	Target Neighborhood Hits	479	Shared Neighborhood Hits	234
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

IL6RB_MOUSE
θ value	5.44631e-05 (rank : 221)	NC score	0.301328 (rank : 247)
Query Neighborhood Hits	600	Target Neighborhood Hits	168	Shared Neighborhood Hits	125
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

ITB6_MOUSE
θ value	5.44631e-05 (rank : 222)	NC score	0.397378 (rank : 126)
Query Neighborhood Hits	600	Target Neighborhood Hits	341	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

WIF1_HUMAN
θ value	5.44631e-05 (rank : 223)	NC score	0.494518 (rank : 78)
Query Neighborhood Hits	600	Target Neighborhood Hits	392	Shared Neighborhood Hits	238
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

DLK_MOUSE
θ value	7.1131e-05 (rank : 224)	NC score	0.502216 (rank : 69)
Query Neighborhood Hits	600	Target Neighborhood Hits	374	Shared Neighborhood Hits	236
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

ITB6_HUMAN
θ value	7.1131e-05 (rank : 225)	NC score	0.390110 (rank : 135)
Query Neighborhood Hits	600	Target Neighborhood Hits	318	Shared Neighborhood Hits	211
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

LRP1B_MOUSE
θ value	7.1131e-05 (rank : 226)	NC score	0.333586 (rank : 211)
Query Neighborhood Hits	600	Target Neighborhood Hits	606	Shared Neighborhood Hits	261
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP8_MOUSE
θ value	7.1131e-05 (rank : 227)	NC score	0.246123 (rank : 326)
Query Neighborhood Hits	600	Target Neighborhood Hits	385	Shared Neighborhood Hits	193
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

ROBO1_HUMAN
θ value	7.1131e-05 (rank : 228)	NC score	0.324141 (rank : 221)
Query Neighborhood Hits	600	Target Neighborhood Hits	529	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

CREL1_HUMAN
θ value	9.29e-05 (rank : 229)	NC score	0.443972 (rank : 110)
Query Neighborhood Hits	600	Target Neighborhood Hits	441	Shared Neighborhood Hits	222
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LTB1L_HUMAN
θ value	9.29e-05 (rank : 230)	NC score	0.354000 (rank : 189)
Query Neighborhood Hits	600	Target Neighborhood Hits	553	Shared Neighborhood Hits	256
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	9.29e-05 (rank : 231)	NC score	0.354370 (rank : 188)
Query Neighborhood Hits	600	Target Neighborhood Hits	502	Shared Neighborhood Hits	244
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

PTPRJ_MOUSE
θ value	9.29e-05 (rank : 232)	NC score	0.191182 (rank : 417)
Query Neighborhood Hits	600	Target Neighborhood Hits	188	Shared Neighborhood Hits	100
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

TNR9_MOUSE
θ value	9.29e-05 (rank : 233)	NC score	0.192575 (rank : 414)
Query Neighborhood Hits	600	Target Neighborhood Hits	137	Shared Neighborhood Hits	88
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

WIF1_MOUSE
θ value	9.29e-05 (rank : 234)	NC score	0.500567 (rank : 71)
Query Neighborhood Hits	600	Target Neighborhood Hits	393	Shared Neighborhood Hits	236
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ITB5_HUMAN
θ value	0.000121331 (rank : 235)	NC score	0.379014 (rank : 152)
Query Neighborhood Hits	600	Target Neighborhood Hits	310	Shared Neighborhood Hits	219
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

LTBP3_HUMAN
θ value	0.000121331 (rank : 236)	NC score	0.358931 (rank : 177)
Query Neighborhood Hits	600	Target Neighborhood Hits	502	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NAGPA_MOUSE
θ value	0.000158464 (rank : 237)	NC score	0.489912 (rank : 81)
Query Neighborhood Hits	600	Target Neighborhood Hits	308	Shared Neighborhood Hits	206
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

SLIT2_MOUSE
θ value	0.000158464 (rank : 238)	NC score	0.349055 (rank : 194)
Query Neighborhood Hits	600	Target Neighborhood Hits	684	Shared Neighborhood Hits	231
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CREL1_MOUSE
θ value	0.00020696 (rank : 239)	NC score	0.425951 (rank : 114)
Query Neighborhood Hits	600	Target Neighborhood Hits	524	Shared Neighborhood Hits	235
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MERTK_MOUSE
θ value	0.00020696 (rank : 240)	NC score	0.151188 (rank : 530)
Query Neighborhood Hits	600	Target Neighborhood Hits	974	Shared Neighborhood Hits	144
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MYOM1_MOUSE
θ value	0.00020696 (rank : 241)	NC score	0.353484 (rank : 190)
Query Neighborhood Hits	600	Target Neighborhood Hits	415	Shared Neighborhood Hits	171
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

COKA1_HUMAN
θ value	0.000270298 (rank : 242)	NC score	0.249619 (rank : 318)
Query Neighborhood Hits	600	Target Neighborhood Hits	403	Shared Neighborhood Hits	129
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

EPHB2_HUMAN
θ value	0.000270298 (rank : 243)	NC score	0.145773 (rank : 545)
Query Neighborhood Hits	600	Target Neighborhood Hits	983	Shared Neighborhood Hits	181
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.000270298 (rank : 244)	NC score	0.145716 (rank : 547)
Query Neighborhood Hits	600	Target Neighborhood Hits	982	Shared Neighborhood Hits	181
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB4_HUMAN
θ value	0.000270298 (rank : 245)	NC score	0.175516 (rank : 469)
Query Neighborhood Hits	600	Target Neighborhood Hits	1056	Shared Neighborhood Hits	246
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

ITB5_MOUSE
θ value	0.000270298 (rank : 246)	NC score	0.386028 (rank : 143)
Query Neighborhood Hits	600	Target Neighborhood Hits	329	Shared Neighborhood Hits	222
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

EPHA1_HUMAN
θ value	0.00035302 (rank : 247)	NC score	0.132245 (rank : 576)
Query Neighborhood Hits	600	Target Neighborhood Hits	997	Shared Neighborhood Hits	183
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA5_MOUSE
θ value	0.00035302 (rank : 248)	NC score	0.125872 (rank : 598)
Query Neighborhood Hits	600	Target Neighborhood Hits	950	Shared Neighborhood Hits	146
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

KRA59_HUMAN
θ value	0.00035302 (rank : 249)	NC score	0.520426 (rank : 52)
Query Neighborhood Hits	600	Target Neighborhood Hits	310	Shared Neighborhood Hits	164
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

MERTK_HUMAN
θ value	0.00035302 (rank : 250)	NC score	0.154491 (rank : 524)
Query Neighborhood Hits	600	Target Neighborhood Hits	988	Shared Neighborhood Hits	142
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

ITB2_MOUSE
θ value	0.000461057 (rank : 251)	NC score	0.388137 (rank : 140)
Query Neighborhood Hits	600	Target Neighborhood Hits	326	Shared Neighborhood Hits	226
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_MOUSE
θ value	0.000461057 (rank : 252)	NC score	0.355579 (rank : 186)
Query Neighborhood Hits	600	Target Neighborhood Hits	319	Shared Neighborhood Hits	209
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

EPHB6_MOUSE
θ value	0.000602161 (rank : 253)	NC score	0.176057 (rank : 465)
Query Neighborhood Hits	600	Target Neighborhood Hits	906	Shared Neighborhood Hits	179
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FBN3_HUMAN
θ value	0.000602161 (rank : 254)	NC score	0.393882 (rank : 129)
Query Neighborhood Hits	600	Target Neighborhood Hits	543	Shared Neighborhood Hits	273
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

ITB7_HUMAN
θ value	0.000602161 (rank : 255)	NC score	0.393011 (rank : 133)
Query Neighborhood Hits	600	Target Neighborhood Hits	290	Shared Neighborhood Hits	206
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

SLIT1_HUMAN
θ value	0.000602161 (rank : 256)	NC score	0.356699 (rank : 182)
Query Neighborhood Hits	600	Target Neighborhood Hits	700	Shared Neighborhood Hits	240
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

ZAN_MOUSE
θ value	0.000602161 (rank : 257)	NC score	0.369428 (rank : 162)
Query Neighborhood Hits	600	Target Neighborhood Hits	808	Shared Neighborhood Hits	311
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KR104_HUMAN
θ value	0.000786445 (rank : 258)	NC score	0.393313 (rank : 130)
Query Neighborhood Hits	600	Target Neighborhood Hits	313	Shared Neighborhood Hits	174
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

NCA12_MOUSE
θ value	0.000786445 (rank : 259)	NC score	0.266295 (rank : 299)
Query Neighborhood Hits	600	Target Neighborhood Hits	399	Shared Neighborhood Hits	117
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

PCSK5_HUMAN
θ value	0.000786445 (rank : 260)	NC score	0.233700 (rank : 344)
Query Neighborhood Hits	600	Target Neighborhood Hits	291	Shared Neighborhood Hits	184
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PTPRO_HUMAN
θ value	0.000786445 (rank : 261)	NC score	0.167527 (rank : 488)
Query Neighborhood Hits	600	Target Neighborhood Hits	139	Shared Neighborhood Hits	65
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

CD45_MOUSE
θ value	0.00102713 (rank : 262)	NC score	0.139739 (rank : 561)
Query Neighborhood Hits	600	Target Neighborhood Hits	178	Shared Neighborhood Hits	59
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

ITB7_MOUSE
θ value	0.00102713 (rank : 263)	NC score	0.393198 (rank : 131)
Query Neighborhood Hits	600	Target Neighborhood Hits	277	Shared Neighborhood Hits	199
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

NELL2_MOUSE
θ value	0.00102713 (rank : 264)	NC score	0.369903 (rank : 160)
Query Neighborhood Hits	600	Target Neighborhood Hits	436	Shared Neighborhood Hits	238
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

CT075_HUMAN
θ value	0.00134147 (rank : 265)	NC score	0.132013 (rank : 579)
Query Neighborhood Hits	600	Target Neighborhood Hits	387	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

EPHB6_HUMAN
θ value	0.00134147 (rank : 266)	NC score	0.185286 (rank : 437)
Query Neighborhood Hits	600	Target Neighborhood Hits	912	Shared Neighborhood Hits	200
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

KRA53_HUMAN
θ value	0.00134147 (rank : 267)	NC score	0.535683 (rank : 51)
Query Neighborhood Hits	600	Target Neighborhood Hits	331	Shared Neighborhood Hits	197
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

TSP2_MOUSE
θ value	0.00134147 (rank : 268)	NC score	0.192439 (rank : 415)
Query Neighborhood Hits	600	Target Neighborhood Hits	352	Shared Neighborhood Hits	177
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TYRO3_HUMAN
θ value	0.00134147 (rank : 269)	NC score	0.161028 (rank : 504)
Query Neighborhood Hits	600	Target Neighborhood Hits	995	Shared Neighborhood Hits	146
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

BOC_HUMAN
θ value	0.00175202 (rank : 270)	NC score	0.316019 (rank : 228)
Query Neighborhood Hits	600	Target Neighborhood Hits	543	Shared Neighborhood Hits	150
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

EPHA6_HUMAN
θ value	0.00175202 (rank : 271)	NC score	0.151103 (rank : 531)
Query Neighborhood Hits	600	Target Neighborhood Hits	959	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

FBLN1_MOUSE
θ value	0.00175202 (rank : 272)	NC score	0.295486 (rank : 256)
Query Neighborhood Hits	600	Target Neighborhood Hits	329	Shared Neighborhood Hits	199
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

HCFC2_MOUSE
θ value	0.00175202 (rank : 273)	NC score	0.251636 (rank : 316)
Query Neighborhood Hits	600	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

NAGPA_HUMAN
θ value	0.00175202 (rank : 274)	NC score	0.475429 (rank : 91)
Query Neighborhood Hits	600	Target Neighborhood Hits	282	Shared Neighborhood Hits	195
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NCAM2_MOUSE
θ value	0.00175202 (rank : 275)	NC score	0.296563 (rank : 254)
Query Neighborhood Hits	600	Target Neighborhood Hits	472	Shared Neighborhood Hits	152
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

UFO_MOUSE
θ value	0.00175202 (rank : 276)	NC score	0.146488 (rank : 544)
Query Neighborhood Hits	600	Target Neighborhood Hits	988	Shared Neighborhood Hits	154
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

CUBN_MOUSE
θ value	0.00228821 (rank : 277)	NC score	0.346925 (rank : 197)
Query Neighborhood Hits	600	Target Neighborhood Hits	477	Shared Neighborhood Hits	233
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

EGFL9_MOUSE
θ value	0.00228821 (rank : 278)	NC score	0.475756 (rank : 90)
Query Neighborhood Hits	600	Target Neighborhood Hits	379	Shared Neighborhood Hits	238
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

HCFC2_HUMAN
θ value	0.00228821 (rank : 279)	NC score	0.184547 (rank : 439)
Query Neighborhood Hits	600	Target Neighborhood Hits	154	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

ITB8_HUMAN
θ value	0.00228821 (rank : 280)	NC score	0.309868 (rank : 232)
Query Neighborhood Hits	600	Target Neighborhood Hits	280	Shared Neighborhood Hits	194
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KRA54_HUMAN
θ value	0.00228821 (rank : 281)	NC score	0.501430 (rank : 70)
Query Neighborhood Hits	600	Target Neighborhood Hits	270	Shared Neighborhood Hits	152
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

DLL3_HUMAN
θ value	0.00298849 (rank : 282)	NC score	0.490779 (rank : 80)
Query Neighborhood Hits	600	Target Neighborhood Hits	419	Shared Neighborhood Hits	239
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

EGFL9_HUMAN
θ value	0.00298849 (rank : 283)	NC score	0.484461 (rank : 84)
Query Neighborhood Hits	600	Target Neighborhood Hits	365	Shared Neighborhood Hits	236
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EPHB4_MOUSE
θ value	0.00298849 (rank : 284)	NC score	0.166349 (rank : 492)
Query Neighborhood Hits	600	Target Neighborhood Hits	1013	Shared Neighborhood Hits	220
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

FBLN1_HUMAN
θ value	0.00298849 (rank : 285)	NC score	0.283111 (rank : 272)
Query Neighborhood Hits	600	Target Neighborhood Hits	324	Shared Neighborhood Hits	202
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

KRA55_HUMAN
θ value	0.00298849 (rank : 286)	NC score	0.502807 (rank : 68)
Query Neighborhood Hits	600	Target Neighborhood Hits	257	Shared Neighborhood Hits	155
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LTBP2_HUMAN
θ value	0.00298849 (rank : 287)	NC score	0.388494 (rank : 138)
Query Neighborhood Hits	600	Target Neighborhood Hits	552	Shared Neighborhood Hits	269
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TNR4_MOUSE
θ value	0.00298849 (rank : 288)	NC score	0.237853 (rank : 335)
Query Neighborhood Hits	600	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

EPHA6_MOUSE
θ value	0.00390308 (rank : 289)	NC score	0.145628 (rank : 548)
Query Neighborhood Hits	600	Target Neighborhood Hits	946	Shared Neighborhood Hits	160
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

KR10A_HUMAN
θ value	0.00390308 (rank : 290)	NC score	0.223669 (rank : 362)
Query Neighborhood Hits	600	Target Neighborhood Hits	232	Shared Neighborhood Hits	129
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

LEPR_MOUSE
θ value	0.00390308 (rank : 291)	NC score	0.109478 (rank : 660)
Query Neighborhood Hits	600	Target Neighborhood Hits	109	Shared Neighborhood Hits	57
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

NELL1_HUMAN
θ value	0.00390308 (rank : 292)	NC score	0.389951 (rank : 137)
Query Neighborhood Hits	600	Target Neighborhood Hits	451	Shared Neighborhood Hits	246
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

PROS_HUMAN
θ value	0.00390308 (rank : 293)	NC score	0.329799 (rank : 216)
Query Neighborhood Hits	600	Target Neighborhood Hits	340	Shared Neighborhood Hits	215
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SSPO_MOUSE
θ value	0.00390308 (rank : 294)	NC score	0.252178 (rank : 313)
Query Neighborhood Hits	600	Target Neighborhood Hits	800	Shared Neighborhood Hits	282
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CSF3R_MOUSE
θ value	0.00509761 (rank : 295)	NC score	0.219512 (rank : 368)
Query Neighborhood Hits	600	Target Neighborhood Hits	104	Shared Neighborhood Hits	79
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

EPHA2_HUMAN
θ value	0.00509761 (rank : 296)	NC score	0.151225 (rank : 529)
Query Neighborhood Hits	600	Target Neighborhood Hits	1021	Shared Neighborhood Hits	190
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

MYPC1_HUMAN
θ value	0.00509761 (rank : 297)	NC score	0.261099 (rank : 305)
Query Neighborhood Hits	600	Target Neighborhood Hits	303	Shared Neighborhood Hits	121
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

NCA11_MOUSE
θ value	0.00509761 (rank : 298)	NC score	0.270229 (rank : 295)
Query Neighborhood Hits	600	Target Neighborhood Hits	661	Shared Neighborhood Hits	141
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

TNR23_MOUSE
θ value	0.00509761 (rank : 299)	NC score	0.205926 (rank : 392)
Query Neighborhood Hits	600	Target Neighborhood Hits	114	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

UFO_HUMAN
θ value	0.00509761 (rank : 300)	NC score	0.142779 (rank : 556)
Query Neighborhood Hits	600	Target Neighborhood Hits	981	Shared Neighborhood Hits	153
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

EPHA2_MOUSE
θ value	0.00665767 (rank : 301)	NC score	0.148009 (rank : 541)
Query Neighborhood Hits	600	Target Neighborhood Hits	1020	Shared Neighborhood Hits	193
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

HCFC1_MOUSE
θ value	0.00665767 (rank : 302)	NC score	0.136161 (rank : 567)
Query Neighborhood Hits	600	Target Neighborhood Hits	348	Shared Neighborhood Hits	82
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

MKS3_MOUSE
θ value	0.00665767 (rank : 303)	NC score	0.199451 (rank : 406)
Query Neighborhood Hits	600	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MYOM2_HUMAN
θ value	0.00665767 (rank : 304)	NC score	0.356144 (rank : 185)
Query Neighborhood Hits	600	Target Neighborhood Hits	341	Shared Neighborhood Hits	150
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

DUET_HUMAN
θ value	0.00869519 (rank : 305)	NC score	0.107661 (rank : 671)
Query Neighborhood Hits	600	Target Neighborhood Hits	1220	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ZNF23_HUMAN
θ value	0.00869519 (rank : 306)	NC score	-0.003568 (rank : 1188)
Query Neighborhood Hits	600	Target Neighborhood Hits	750	Shared Neighborhood Hits	37
SwissProt Accessions	P17027, Q96IT3, Q9UG42	Gene names	ZNF23, KOX16, ZNF359
Domain Architecture
Description	Zinc finger protein 23 (Zinc finger protein 359) (Zinc finger protein KOX16).

CD45_HUMAN
θ value	0.0113563 (rank : 307)	NC score	0.147257 (rank : 543)
Query Neighborhood Hits	600	Target Neighborhood Hits	243	Shared Neighborhood Hits	72
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CSPG4_HUMAN
θ value	0.0113563 (rank : 308)	NC score	0.131022 (rank : 582)
Query Neighborhood Hits	600	Target Neighborhood Hits	112	Shared Neighborhood Hits	41
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

GAS6_HUMAN
θ value	0.0113563 (rank : 309)	NC score	0.326220 (rank : 219)
Query Neighborhood Hits	600	Target Neighborhood Hits	348	Shared Neighborhood Hits	213
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ITB2_HUMAN
θ value	0.0113563 (rank : 310)	NC score	0.367414 (rank : 165)
Query Neighborhood Hits	600	Target Neighborhood Hits	282	Shared Neighborhood Hits	211
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

MYT1_MOUSE
θ value	0.0113563 (rank : 311)	NC score	0.034147 (rank : 1086)
Query Neighborhood Hits	600	Target Neighborhood Hits	385	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

UROM_HUMAN
θ value	0.0113563 (rank : 312)	NC score	0.295963 (rank : 255)
Query Neighborhood Hits	600	Target Neighborhood Hits	284	Shared Neighborhood Hits	181
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

EPHA1_MOUSE
θ value	0.0148317 (rank : 313)	NC score	0.128421 (rank : 595)
Query Neighborhood Hits	600	Target Neighborhood Hits	958	Shared Neighborhood Hits	180
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

TARSH_HUMAN
θ value	0.0148317 (rank : 314)	NC score	0.186949 (rank : 430)
Query Neighborhood Hits	600	Target Neighborhood Hits	768	Shared Neighborhood Hits	131
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

DLL3_MOUSE
θ value	0.0193708 (rank : 315)	NC score	0.484389 (rank : 85)
Query Neighborhood Hits	600	Target Neighborhood Hits	399	Shared Neighborhood Hits	237
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EDIL3_MOUSE
θ value	0.0193708 (rank : 316)	NC score	0.345072 (rank : 199)
Query Neighborhood Hits	600	Target Neighborhood Hits	317	Shared Neighborhood Hits	191
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

ITB3_HUMAN
θ value	0.0193708 (rank : 317)	NC score	0.359429 (rank : 174)
Query Neighborhood Hits	600	Target Neighborhood Hits	325	Shared Neighborhood Hits	218
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KRA57_HUMAN
θ value	0.0193708 (rank : 318)	NC score	0.495233 (rank : 77)
Query Neighborhood Hits	600	Target Neighborhood Hits	269	Shared Neighborhood Hits	156
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	0.0193708 (rank : 319)	NC score	0.493479 (rank : 79)
Query Neighborhood Hits	600	Target Neighborhood Hits	324	Shared Neighborhood Hits	181
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

NID1_MOUSE
θ value	0.0193708 (rank : 320)	NC score	0.297380 (rank : 253)
Query Neighborhood Hits	600	Target Neighborhood Hits	335	Shared Neighborhood Hits	192
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PCSK6_HUMAN
θ value	0.0193708 (rank : 321)	NC score	0.208561 (rank : 391)
Query Neighborhood Hits	600	Target Neighborhood Hits	298	Shared Neighborhood Hits	154
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

SPEG_MOUSE
θ value	0.0193708 (rank : 322)	NC score	0.130331 (rank : 587)
Query Neighborhood Hits	600	Target Neighborhood Hits	1959	Shared Neighborhood Hits	161
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TSP2_HUMAN
θ value	0.0193708 (rank : 323)	NC score	0.182263 (rank : 447)
Query Neighborhood Hits	600	Target Neighborhood Hits	359	Shared Neighborhood Hits	175
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TYRO3_MOUSE
θ value	0.0193708 (rank : 324)	NC score	0.159105 (rank : 510)
Query Neighborhood Hits	600	Target Neighborhood Hits	1007	Shared Neighborhood Hits	150
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

ZN611_HUMAN
θ value	0.0193708 (rank : 325)	NC score	-0.003262 (rank : 1187)
Query Neighborhood Hits	600	Target Neighborhood Hits	769	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N823, Q69YG9	Gene names	ZNF611
Domain Architecture	No domain graphic available
Description	Zinc finger protein 611.

CT075_MOUSE
θ value	0.0252991 (rank : 326)	NC score	0.105130 (rank : 678)
Query Neighborhood Hits	600	Target Neighborhood Hits	358	Shared Neighborhood Hits	69
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

HCFC1_HUMAN
θ value	0.0252991 (rank : 327)	NC score	0.121835 (rank : 620)
Query Neighborhood Hits	600	Target Neighborhood Hits	331	Shared Neighborhood Hits	69
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

NID1_HUMAN
θ value	0.0252991 (rank : 328)	NC score	0.302585 (rank : 246)
Query Neighborhood Hits	600	Target Neighborhood Hits	329	Shared Neighborhood Hits	197
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NPHN_HUMAN
θ value	0.0252991 (rank : 329)	NC score	0.284355 (rank : 267)
Query Neighborhood Hits	600	Target Neighborhood Hits	362	Shared Neighborhood Hits	122
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

PTPRJ_HUMAN
θ value	0.0252991 (rank : 330)	NC score	0.187248 (rank : 429)
Query Neighborhood Hits	600	Target Neighborhood Hits	207	Shared Neighborhood Hits	103
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

SPEG_HUMAN
θ value	0.0252991 (rank : 331)	NC score	0.130212 (rank : 588)
Query Neighborhood Hits	600	Target Neighborhood Hits	1762	Shared Neighborhood Hits	161
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TSP4_HUMAN
θ value	0.0252991 (rank : 332)	NC score	0.306715 (rank : 240)
Query Neighborhood Hits	600	Target Neighborhood Hits	277	Shared Neighborhood Hits	186
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

BOC_MOUSE
θ value	0.0330416 (rank : 333)	NC score	0.309346 (rank : 234)
Query Neighborhood Hits	600	Target Neighborhood Hits	433	Shared Neighborhood Hits	138
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CUBN_HUMAN
θ value	0.0330416 (rank : 334)	NC score	0.350424 (rank : 193)
Query Neighborhood Hits	600	Target Neighborhood Hits	482	Shared Neighborhood Hits	232
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

MATN3_MOUSE
θ value	0.0330416 (rank : 335)	NC score	0.217460 (rank : 372)
Query Neighborhood Hits	600	Target Neighborhood Hits	261	Shared Neighborhood Hits	148
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MYT1_HUMAN
θ value	0.0330416 (rank : 336)	NC score	0.029793 (rank : 1097)
Query Neighborhood Hits	600	Target Neighborhood Hits	475	Shared Neighborhood Hits	18
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

NCA11_HUMAN
θ value	0.0330416 (rank : 337)	NC score	0.271443 (rank : 293)
Query Neighborhood Hits	600	Target Neighborhood Hits	443	Shared Neighborhood Hits	132
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

TNR25_HUMAN
θ value	0.0330416 (rank : 338)	NC score	0.211670 (rank : 381)
Query Neighborhood Hits	600	Target Neighborhood Hits	172	Shared Neighborhood Hits	100
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

VLDLR_MOUSE
θ value	0.0330416 (rank : 339)	NC score	0.244573 (rank : 328)
Query Neighborhood Hits	600	Target Neighborhood Hits	360	Shared Neighborhood Hits	193
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

CSTN3_HUMAN
θ value	0.0431538 (rank : 340)	NC score	0.040311 (rank : 1079)
Query Neighborhood Hits	600	Target Neighborhood Hits	145	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BQT9, O94831	Gene names	CLSTN3, CS3, KIAA0726
Domain Architecture
Description	Calsyntenin-3 precursor.

KR107_HUMAN
θ value	0.0431538 (rank : 341)	NC score	0.371863 (rank : 156)
Query Neighborhood Hits	600	Target Neighborhood Hits	330	Shared Neighborhood Hits	184
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

MATN2_HUMAN
θ value	0.0431538 (rank : 342)	NC score	0.286465 (rank : 265)
Query Neighborhood Hits	600	Target Neighborhood Hits	365	Shared Neighborhood Hits	200
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

NPHN_MOUSE
θ value	0.0431538 (rank : 343)	NC score	0.273018 (rank : 288)
Query Neighborhood Hits	600	Target Neighborhood Hits	370	Shared Neighborhood Hits	126
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

FHL2_MOUSE
θ value	0.0563607 (rank : 344)	NC score	0.029947 (rank : 1096)
Query Neighborhood Hits	600	Target Neighborhood Hits	539	Shared Neighborhood Hits	60
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

KR511_HUMAN
θ value	0.0563607 (rank : 345)	NC score	0.440106 (rank : 111)
Query Neighborhood Hits	600	Target Neighborhood Hits	231	Shared Neighborhood Hits	129
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

MYPC3_HUMAN
θ value	0.0563607 (rank : 346)	NC score	0.272490 (rank : 291)
Query Neighborhood Hits	600	Target Neighborhood Hits	318	Shared Neighborhood Hits	136
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

RIMB2_HUMAN
θ value	0.0563607 (rank : 347)	NC score	0.124962 (rank : 604)
Query Neighborhood Hits	600	Target Neighborhood Hits	263	Shared Neighborhood Hits	62
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

TR10A_HUMAN
θ value	0.0563607 (rank : 348)	NC score	0.064311 (rank : 921)
Query Neighborhood Hits	600	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

EPHAA_HUMAN
θ value	0.0736092 (rank : 349)	NC score	0.149642 (rank : 535)
Query Neighborhood Hits	600	Target Neighborhood Hits	960	Shared Neighborhood Hits	164
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

LRP10_HUMAN
θ value	0.0736092 (rank : 350)	NC score	0.137620 (rank : 564)
Query Neighborhood Hits	600	Target Neighborhood Hits	197	Shared Neighborhood Hits	77
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MYPC3_MOUSE
θ value	0.0736092 (rank : 351)	NC score	0.271075 (rank : 294)
Query Neighborhood Hits	600	Target Neighborhood Hits	310	Shared Neighborhood Hits	137
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NCAM2_HUMAN
θ value	0.0736092 (rank : 352)	NC score	0.287443 (rank : 263)
Query Neighborhood Hits	600	Target Neighborhood Hits	441	Shared Neighborhood Hits	148
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

ZN287_HUMAN
θ value	0.0736092 (rank : 353)	NC score	-0.004551 (rank : 1198)
Query Neighborhood Hits	600	Target Neighborhood Hits	777	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HBT7	Gene names	ZNF287
Domain Architecture
Description	Zinc finger protein 287.

COFA1_MOUSE
θ value	0.0961366 (rank : 354)	NC score	0.030195 (rank : 1095)
Query Neighborhood Hits	600	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

KRA52_HUMAN
θ value	0.0961366 (rank : 355)	NC score	0.454278 (rank : 104)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	141
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

MYT1L_MOUSE
θ value	0.0961366 (rank : 356)	NC score	0.029046 (rank : 1098)
Query Neighborhood Hits	600	Target Neighborhood Hits	461	Shared Neighborhood Hits	19
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

NCA12_HUMAN
θ value	0.0961366 (rank : 357)	NC score	0.261259 (rank : 304)
Query Neighborhood Hits	600	Target Neighborhood Hits	437	Shared Neighborhood Hits	126
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

SAMH1_HUMAN
θ value	0.0961366 (rank : 358)	NC score	0.032121 (rank : 1090)
Query Neighborhood Hits	600	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3Z3, Q5JXG8, Q9H004, Q9H005, Q9H3U9	Gene names	SAMHD1, MOP5
Domain Architecture
Description	SAM domain and HD domain-containing protein 1 (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5).

SAMH1_MOUSE
θ value	0.0961366 (rank : 359)	NC score	0.031735 (rank : 1092)
Query Neighborhood Hits	600	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q60710, Q91VK8	Gene names	Samhd1, Mg11
Domain Architecture
Description	SAM domain and HD domain-containing protein 1 (Interferon-gamma- inducible protein Mg11).

TNR16_HUMAN
θ value	0.0961366 (rank : 360)	NC score	0.225725 (rank : 359)
Query Neighborhood Hits	600	Target Neighborhood Hits	183	Shared Neighborhood Hits	118
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

CORIN_HUMAN
θ value	0.125558 (rank : 361)	NC score	0.102005 (rank : 688)
Query Neighborhood Hits	600	Target Neighborhood Hits	453	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

KR106_HUMAN
θ value	0.125558 (rank : 362)	NC score	0.357677 (rank : 179)
Query Neighborhood Hits	600	Target Neighborhood Hits	347	Shared Neighborhood Hits	194
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

LRP10_MOUSE
θ value	0.125558 (rank : 363)	NC score	0.131661 (rank : 581)
Query Neighborhood Hits	600	Target Neighborhood Hits	169	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LYAM2_HUMAN
θ value	0.125558 (rank : 364)	NC score	0.184612 (rank : 438)
Query Neighborhood Hits	600	Target Neighborhood Hits	394	Shared Neighborhood Hits	181
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MYT1L_HUMAN
θ value	0.125558 (rank : 365)	NC score	0.027751 (rank : 1099)
Query Neighborhood Hits	600	Target Neighborhood Hits	471	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

TNR16_MOUSE
θ value	0.125558 (rank : 366)	NC score	0.208967 (rank : 385)
Query Neighborhood Hits	600	Target Neighborhood Hits	178	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

ZN184_HUMAN
θ value	0.125558 (rank : 367)	NC score	-0.002269 (rank : 1181)
Query Neighborhood Hits	600	Target Neighborhood Hits	811	Shared Neighborhood Hits	45
SwissProt Accessions	Q99676, O60792, Q8TBA9	Gene names	ZNF184
Domain Architecture
Description	Zinc finger protein 184.

LRP2_HUMAN
θ value	0.163984 (rank : 368)	NC score	0.280342 (rank : 276)
Query Neighborhood Hits	600	Target Neighborhood Hits	573	Shared Neighborhood Hits	262
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LYAM3_HUMAN
θ value	0.163984 (rank : 369)	NC score	0.176827 (rank : 461)
Query Neighborhood Hits	600	Target Neighborhood Hits	378	Shared Neighborhood Hits	166
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

SPY1_HUMAN
θ value	0.163984 (rank : 370)	NC score	0.046521 (rank : 1072)
Query Neighborhood Hits	600	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

TNR22_MOUSE
θ value	0.163984 (rank : 371)	NC score	0.175268 (rank : 471)
Query Neighborhood Hits	600	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

DGKE_HUMAN
θ value	0.21417 (rank : 372)	NC score	0.012556 (rank : 1129)
Query Neighborhood Hits	600	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P52429, Q9UKQ3	Gene names	DGKE, DAGK5
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

EDIL3_HUMAN
θ value	0.21417 (rank : 373)	NC score	0.315122 (rank : 229)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	177
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FLRT1_HUMAN
θ value	0.21417 (rank : 374)	NC score	0.019885 (rank : 1117)
Query Neighborhood Hits	600	Target Neighborhood Hits	286	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

KR510_HUMAN
θ value	0.21417 (rank : 375)	NC score	0.455229 (rank : 102)
Query Neighborhood Hits	600	Target Neighborhood Hits	217	Shared Neighborhood Hits	123
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

MKS3_HUMAN
θ value	0.21417 (rank : 376)	NC score	0.147655 (rank : 542)
Query Neighborhood Hits	600	Target Neighborhood Hits	79	Shared Neighborhood Hits	71
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

TNR9_HUMAN
θ value	0.21417 (rank : 377)	NC score	0.123974 (rank : 608)
Query Neighborhood Hits	600	Target Neighborhood Hits	166	Shared Neighborhood Hits	112
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

CRLF1_MOUSE
θ value	0.279714 (rank : 378)	NC score	0.165106 (rank : 497)
Query Neighborhood Hits	600	Target Neighborhood Hits	116	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CSTN3_MOUSE
θ value	0.279714 (rank : 379)	NC score	0.038698 (rank : 1081)
Query Neighborhood Hits	600	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q99JH7	Gene names	Clstn3, Cs3, Cstn3
Domain Architecture
Description	Calsyntenin-3 precursor.

FHL2_HUMAN
θ value	0.279714 (rank : 380)	NC score	0.022522 (rank : 1111)
Query Neighborhood Hits	600	Target Neighborhood Hits	533	Shared Neighborhood Hits	58
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

LDLR_MOUSE
θ value	0.279714 (rank : 381)	NC score	0.232035 (rank : 352)
Query Neighborhood Hits	600	Target Neighborhood Hits	382	Shared Neighborhood Hits	196
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MYPC2_MOUSE
θ value	0.279714 (rank : 382)	NC score	0.273156 (rank : 287)
Query Neighborhood Hits	600	Target Neighborhood Hits	297	Shared Neighborhood Hits	122
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

TNR14_HUMAN
θ value	0.279714 (rank : 383)	NC score	0.169230 (rank : 480)
Query Neighborhood Hits	600	Target Neighborhood Hits	149	Shared Neighborhood Hits	102
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ZN155_HUMAN
θ value	0.279714 (rank : 384)	NC score	0.001817 (rank : 1167)
Query Neighborhood Hits	600	Target Neighborhood Hits	786	Shared Neighborhood Hits	54
SwissProt Accessions	Q12901, Q9UIE1, Q9UK14	Gene names	ZNF155
Domain Architecture
Description	Zinc finger protein 155.

ADAM8_HUMAN
θ value	0.365318 (rank : 385)	NC score	0.082199 (rank : 815)
Query Neighborhood Hits	600	Target Neighborhood Hits	327	Shared Neighborhood Hits	151
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

CRLF1_HUMAN
θ value	0.365318 (rank : 386)	NC score	0.165643 (rank : 493)
Query Neighborhood Hits	600	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

FAT2_HUMAN
θ value	0.365318 (rank : 387)	NC score	0.172129 (rank : 473)
Query Neighborhood Hits	600	Target Neighborhood Hits	507	Shared Neighborhood Hits	186
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

HABP2_HUMAN
θ value	0.365318 (rank : 388)	NC score	0.181774 (rank : 450)
Query Neighborhood Hits	600	Target Neighborhood Hits	431	Shared Neighborhood Hits	186
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LRP4_HUMAN
θ value	0.365318 (rank : 389)	NC score	0.212830 (rank : 378)
Query Neighborhood Hits	600	Target Neighborhood Hits	355	Shared Neighborhood Hits	180
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

OBSCN_HUMAN
θ value	0.365318 (rank : 390)	NC score	0.132041 (rank : 578)
Query Neighborhood Hits	600	Target Neighborhood Hits	1931	Shared Neighborhood Hits	174
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TNR4_HUMAN
θ value	0.365318 (rank : 391)	NC score	0.213884 (rank : 375)
Query Neighborhood Hits	600	Target Neighborhood Hits	152	Shared Neighborhood Hits	90
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR7_HUMAN
θ value	0.365318 (rank : 392)	NC score	0.165625 (rank : 494)
Query Neighborhood Hits	600	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TSP1_MOUSE
θ value	0.365318 (rank : 393)	NC score	0.222980 (rank : 363)
Query Neighborhood Hits	600	Target Neighborhood Hits	396	Shared Neighborhood Hits	199
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP3_HUMAN
θ value	0.365318 (rank : 394)	NC score	0.289911 (rank : 262)
Query Neighborhood Hits	600	Target Neighborhood Hits	250	Shared Neighborhood Hits	165
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

ZN33A_HUMAN
θ value	0.365318 (rank : 395)	NC score	-0.004212 (rank : 1194)
Query Neighborhood Hits	600	Target Neighborhood Hits	780	Shared Neighborhood Hits	33
SwissProt Accessions	Q06730, Q5VZ86	Gene names	ZNF33A, KIAA0065, KOX31, ZNF33
Domain Architecture
Description	Zinc finger protein 33A (Zinc finger protein KOX31) (Zinc finger and ZAK-associated protein with KRAB domain) (ZZaPK).

CSPG3_MOUSE
θ value	0.47712 (rank : 396)	NC score	0.251782 (rank : 315)
Query Neighborhood Hits	600	Target Neighborhood Hits	657	Shared Neighborhood Hits	206
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ERBB3_HUMAN
θ value	0.47712 (rank : 397)	NC score	0.087766 (rank : 783)
Query Neighborhood Hits	600	Target Neighborhood Hits	918	Shared Neighborhood Hits	121
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

SORC1_HUMAN
θ value	0.47712 (rank : 398)	NC score	0.026195 (rank : 1102)
Query Neighborhood Hits	600	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WY21, Q59GG7, Q5JVT7, Q5JVT8, Q5VY14, Q86WQ1, Q86WQ2, Q9H1Y1, Q9H1Y2	Gene names	SORCS1, SORCS
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (hSorCS).

SORC1_MOUSE
θ value	0.47712 (rank : 399)	NC score	0.026335 (rank : 1101)
Query Neighborhood Hits	600	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JLC4, Q8VI45, Q922I1, Q9QY21	Gene names	Sorcs1, Sorcs
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (mSorCS).

SPY1_MOUSE
θ value	0.47712 (rank : 400)	NC score	0.053694 (rank : 1015)
Query Neighborhood Hits	600	Target Neighborhood Hits	57	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

ADA11_HUMAN
θ value	0.62314 (rank : 401)	NC score	0.091713 (rank : 743)
Query Neighborhood Hits	600	Target Neighborhood Hits	259	Shared Neighborhood Hits	153
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CT111_HUMAN
θ value	0.62314 (rank : 402)	NC score	0.030866 (rank : 1093)
Query Neighborhood Hits	600	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NX31, O95912, Q9NZ84, Q9P0R8	Gene names	C20orf111
Domain Architecture
Description	Uncharacterized protein C20orf111.

GP112_HUMAN
θ value	0.62314 (rank : 403)	NC score	0.048850 (rank : 1069)
Query Neighborhood Hits	600	Target Neighborhood Hits	441	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

IL27B_HUMAN
θ value	0.62314 (rank : 404)	NC score	0.142510 (rank : 557)
Query Neighborhood Hits	600	Target Neighborhood Hits	80	Shared Neighborhood Hits	61
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

LYPD3_MOUSE
θ value	0.62314 (rank : 405)	NC score	0.016376 (rank : 1124)
Query Neighborhood Hits	600	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YK8	Gene names	Lypd3, C4.4a
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 3 precursor (GPI-anchored metastasis-associated protein C4.4A homolog).

PME17_HUMAN
θ value	0.62314 (rank : 406)	NC score	0.022754 (rank : 1110)
Query Neighborhood Hits	600	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P40967, Q12763, Q14448, Q14817, Q16565	Gene names	SILV, D12S53E, PMEL17
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Melanocyte lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (ME20M/ME20S) (ME20- M/ME20-S) (95 kDa melanocyte-specific secreted glycoprotein).

VWF_HUMAN
θ value	0.62314 (rank : 407)	NC score	0.204193 (rank : 396)
Query Neighborhood Hits	600	Target Neighborhood Hits	396	Shared Neighborhood Hits	194
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ZAN_HUMAN
θ value	0.62314 (rank : 408)	NC score	0.199473 (rank : 405)
Query Neighborhood Hits	600	Target Neighborhood Hits	679	Shared Neighborhood Hits	227
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZN235_MOUSE
θ value	0.62314 (rank : 409)	NC score	-0.004418 (rank : 1196)
Query Neighborhood Hits	600	Target Neighborhood Hits	768	Shared Neighborhood Hits	41
SwissProt Accessions	Q61116, Q3UKA3, Q8CE70	Gene names	Znf235, Zfp93
Domain Architecture
Description	Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93).

ZN678_HUMAN
θ value	0.62314 (rank : 410)	NC score	-0.000561 (rank : 1176)
Query Neighborhood Hits	600	Target Neighborhood Hits	761	Shared Neighborhood Hits	44
SwissProt Accessions	Q5SXM1, Q8IVQ9	Gene names	ZNF678
Domain Architecture	No domain graphic available
Description	Zinc finger protein 678.

ADA22_HUMAN
θ value	0.813845 (rank : 411)	NC score	0.061629 (rank : 943)
Query Neighborhood Hits	600	Target Neighborhood Hits	211	Shared Neighborhood Hits	114
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

BPAEA_HUMAN
θ value	0.813845 (rank : 412)	NC score	0.023265 (rank : 1107)
Query Neighborhood Hits	600	Target Neighborhood Hits	1369	Shared Neighborhood Hits	32
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

HGFA_MOUSE
θ value	0.813845 (rank : 413)	NC score	0.123235 (rank : 612)
Query Neighborhood Hits	600	Target Neighborhood Hits	419	Shared Neighborhood Hits	164
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

KALM_HUMAN
θ value	0.813845 (rank : 414)	NC score	0.218455 (rank : 370)
Query Neighborhood Hits	600	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

KRHB1_HUMAN
θ value	0.813845 (rank : 415)	NC score	0.005939 (rank : 1147)
Query Neighborhood Hits	600	Target Neighborhood Hits	461	Shared Neighborhood Hits	33
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

MAML3_HUMAN
θ value	0.813845 (rank : 416)	NC score	0.014779 (rank : 1125)
Query Neighborhood Hits	600	Target Neighborhood Hits	323	Shared Neighborhood Hits	20
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

PTX3_HUMAN
θ value	0.813845 (rank : 417)	NC score	0.025641 (rank : 1103)
Query Neighborhood Hits	600	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	P26022	Gene names	PTX3, TSG14
Domain Architecture
Description	Pentraxin-related protein PTX3 precursor (Pentaxin-related protein PTX3) (Tumor necrosis factor-inducible protein TSG-14).

TNR8_HUMAN
θ value	0.813845 (rank : 418)	NC score	0.112750 (rank : 646)
Query Neighborhood Hits	600	Target Neighborhood Hits	198	Shared Neighborhood Hits	85
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TSP1_HUMAN
θ value	0.813845 (rank : 419)	NC score	0.219064 (rank : 369)
Query Neighborhood Hits	600	Target Neighborhood Hits	389	Shared Neighborhood Hits	199
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

ADA28_HUMAN
θ value	1.06291 (rank : 420)	NC score	0.054124 (rank : 1009)
Query Neighborhood Hits	600	Target Neighborhood Hits	244	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

COMP_MOUSE
θ value	1.06291 (rank : 421)	NC score	0.326456 (rank : 218)
Query Neighborhood Hits	600	Target Neighborhood Hits	290	Shared Neighborhood Hits	202
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KR171_HUMAN
θ value	1.06291 (rank : 422)	NC score	0.400957 (rank : 123)
Query Neighborhood Hits	600	Target Neighborhood Hits	144	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LRP12_HUMAN
θ value	1.06291 (rank : 423)	NC score	0.082544 (rank : 812)
Query Neighborhood Hits	600	Target Neighborhood Hits	205	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

MAST1_MOUSE
θ value	1.06291 (rank : 424)	NC score	0.009722 (rank : 1133)
Query Neighborhood Hits	600	Target Neighborhood Hits	1123	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MATN4_MOUSE
θ value	1.06291 (rank : 425)	NC score	0.209332 (rank : 384)
Query Neighborhood Hits	600	Target Neighborhood Hits	277	Shared Neighborhood Hits	150
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

PCDBF_HUMAN
θ value	1.06291 (rank : 426)	NC score	0.023022 (rank : 1109)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5E8, Q8IUX5	Gene names	PCDHB15
Domain Architecture
Description	Protocadherin beta 15 precursor (PCDH-beta15).

SHBG_MOUSE
θ value	1.06291 (rank : 427)	NC score	0.176632 (rank : 463)
Query Neighborhood Hits	600	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SSRG_HUMAN
θ value	1.06291 (rank : 428)	NC score	0.023256 (rank : 1108)
Query Neighborhood Hits	600	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNL2	Gene names	SSR3, TRAPG
Domain Architecture
Description	Translocon-associated protein subunit gamma (TRAP-gamma) (Signal sequence receptor subunit gamma) (SSR-gamma).

TRI18_MOUSE
θ value	1.06291 (rank : 429)	NC score	0.014694 (rank : 1126)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	27
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

CI079_HUMAN
θ value	1.38821 (rank : 430)	NC score	0.019040 (rank : 1120)
Query Neighborhood Hits	600	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CO5A1_HUMAN
θ value	1.38821 (rank : 431)	NC score	0.022498 (rank : 1112)
Query Neighborhood Hits	600	Target Neighborhood Hits	434	Shared Neighborhood Hits	33
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

KRA56_HUMAN
θ value	1.38821 (rank : 432)	NC score	0.439795 (rank : 112)
Query Neighborhood Hits	600	Target Neighborhood Hits	207	Shared Neighborhood Hits	134
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

MT1H_HUMAN
θ value	1.38821 (rank : 433)	NC score	0.141309 (rank : 558)
Query Neighborhood Hits	600	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

PAP2_HUMAN
θ value	1.38821 (rank : 434)	NC score	0.039285 (rank : 1080)
Query Neighborhood Hits	600	Target Neighborhood Hits	106	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PROS_MOUSE
θ value	1.38821 (rank : 435)	NC score	0.320897 (rank : 224)
Query Neighborhood Hits	600	Target Neighborhood Hits	330	Shared Neighborhood Hits	211
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SMS2_HUMAN
θ value	1.38821 (rank : 436)	NC score	0.010609 (rank : 1132)
Query Neighborhood Hits	600	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHU3	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

SSRG_MOUSE
θ value	1.38821 (rank : 437)	NC score	0.022226 (rank : 1113)
Query Neighborhood Hits	600	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DCF9, Q8C0Z8	Gene names	Ssr3
Domain Architecture	No domain graphic available
Description	Translocon-associated protein subunit gamma (TRAP-gamma) (Signal sequence receptor subunit gamma) (SSR-gamma).

TR10D_HUMAN
θ value	1.38821 (rank : 438)	NC score	0.043404 (rank : 1075)
Query Neighborhood Hits	600	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

ADA22_MOUSE
θ value	1.81305 (rank : 439)	NC score	0.068773 (rank : 896)
Query Neighborhood Hits	600	Target Neighborhood Hits	225	Shared Neighborhood Hits	121
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ANR38_MOUSE
θ value	1.81305 (rank : 440)	NC score	0.032318 (rank : 1089)
Query Neighborhood Hits	600	Target Neighborhood Hits	512	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

BRWD1_MOUSE
θ value	1.81305 (rank : 441)	NC score	-0.002742 (rank : 1182)
Query Neighborhood Hits	600	Target Neighborhood Hits	478	Shared Neighborhood Hits	11
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CSPG3_HUMAN
θ value	1.81305 (rank : 442)	NC score	0.246533 (rank : 323)
Query Neighborhood Hits	600	Target Neighborhood Hits	676	Shared Neighborhood Hits	208
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ESM1_MOUSE
θ value	1.81305 (rank : 443)	NC score	0.208881 (rank : 386)
Query Neighborhood Hits	600	Target Neighborhood Hits	107	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FRMD6_HUMAN
θ value	1.81305 (rank : 444)	NC score	0.008742 (rank : 1139)
Query Neighborhood Hits	600	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

LYAM2_MOUSE
θ value	1.81305 (rank : 445)	NC score	0.204649 (rank : 395)
Query Neighborhood Hits	600	Target Neighborhood Hits	420	Shared Neighborhood Hits	195
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_MOUSE
θ value	1.81305 (rank : 446)	NC score	0.188163 (rank : 426)
Query Neighborhood Hits	600	Target Neighborhood Hits	390	Shared Neighborhood Hits	169
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MDGA1_HUMAN
θ value	1.81305 (rank : 447)	NC score	0.240992 (rank : 333)
Query Neighborhood Hits	600	Target Neighborhood Hits	358	Shared Neighborhood Hits	94
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MT1A_HUMAN
θ value	1.81305 (rank : 448)	NC score	0.167815 (rank : 486)
Query Neighborhood Hits	600	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT3_MOUSE
θ value	1.81305 (rank : 449)	NC score	0.276818 (rank : 280)
Query Neighborhood Hits	600	Target Neighborhood Hits	68	Shared Neighborhood Hits	49
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MUC2_HUMAN
θ value	1.81305 (rank : 450)	NC score	0.123960 (rank : 609)
Query Neighborhood Hits	600	Target Neighborhood Hits	906	Shared Neighborhood Hits	169
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MYLK_HUMAN
θ value	1.81305 (rank : 451)	NC score	0.132410 (rank : 575)
Query Neighborhood Hits	600	Target Neighborhood Hits	1328	Shared Neighborhood Hits	150
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYLK_MOUSE
θ value	1.81305 (rank : 452)	NC score	0.131850 (rank : 580)
Query Neighborhood Hits	600	Target Neighborhood Hits	1489	Shared Neighborhood Hits	157
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYPC2_HUMAN
θ value	1.81305 (rank : 453)	NC score	0.266899 (rank : 298)
Query Neighborhood Hits	600	Target Neighborhood Hits	316	Shared Neighborhood Hits	130
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NID2_HUMAN
θ value	1.81305 (rank : 454)	NC score	0.304998 (rank : 243)
Query Neighborhood Hits	600	Target Neighborhood Hits	456	Shared Neighborhood Hits	210
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

PELI3_HUMAN
θ value	1.81305 (rank : 455)	NC score	0.009314 (rank : 1134)
Query Neighborhood Hits	600	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N2H9, Q8N3E1, Q8N9Q6, Q8TAW7, Q8TED5	Gene names	PELI3
Domain Architecture
Description	Protein pellino homolog 3 (Pellino-3).

PELI3_MOUSE
θ value	1.81305 (rank : 456)	NC score	0.009289 (rank : 1136)
Query Neighborhood Hits	600	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BXR6, Q8K329	Gene names	Peli3
Domain Architecture
Description	Protein pellino homolog 3 (Pellino-3).

RIMB2_MOUSE
θ value	1.81305 (rank : 457)	NC score	0.119022 (rank : 626)
Query Neighborhood Hits	600	Target Neighborhood Hits	246	Shared Neighborhood Hits	55
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ROBO4_HUMAN
θ value	1.81305 (rank : 458)	NC score	0.274475 (rank : 285)
Query Neighborhood Hits	600	Target Neighborhood Hits	364	Shared Neighborhood Hits	111
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

TNR1A_MOUSE
θ value	1.81305 (rank : 459)	NC score	0.088152 (rank : 780)
Query Neighborhood Hits	600	Target Neighborhood Hits	131	Shared Neighborhood Hits	66
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TRIM9_MOUSE
θ value	1.81305 (rank : 460)	NC score	0.044511 (rank : 1074)
Query Neighborhood Hits	600	Target Neighborhood Hits	274	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TSP4_MOUSE
θ value	1.81305 (rank : 461)	NC score	0.307852 (rank : 238)
Query Neighborhood Hits	600	Target Neighborhood Hits	276	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

ZDHC1_HUMAN
θ value	1.81305 (rank : 462)	NC score	0.009265 (rank : 1137)
Query Neighborhood Hits	600	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

ZN490_HUMAN
θ value	1.81305 (rank : 463)	NC score	-0.005260 (rank : 1200)
Query Neighborhood Hits	600	Target Neighborhood Hits	754	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ULM2	Gene names	ZNF490, KIAA1198
Domain Architecture
Description	Zinc finger protein 490.

ESM1_HUMAN
θ value	2.36792 (rank : 464)	NC score	0.235961 (rank : 339)
Query Neighborhood Hits	600	Target Neighborhood Hits	110	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

GAS6_MOUSE
θ value	2.36792 (rank : 465)	NC score	0.321630 (rank : 223)
Query Neighborhood Hits	600	Target Neighborhood Hits	343	Shared Neighborhood Hits	217
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

IGHA1_HUMAN
θ value	2.36792 (rank : 466)	NC score	0.005176 (rank : 1151)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	10
SwissProt Accessions	P01876	Gene names	IGHA1
Domain Architecture
Description	Ig alpha-1 chain C region.

TACD1_HUMAN
θ value	2.36792 (rank : 467)	NC score	0.017588 (rank : 1122)
Query Neighborhood Hits	600	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

TNR1A_HUMAN
θ value	2.36792 (rank : 468)	NC score	0.065912 (rank : 916)
Query Neighborhood Hits	600	Target Neighborhood Hits	121	Shared Neighborhood Hits	59
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR7_MOUSE
θ value	2.36792 (rank : 469)	NC score	0.121300 (rank : 624)
Query Neighborhood Hits	600	Target Neighborhood Hits	112	Shared Neighborhood Hits	77
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TSP3_MOUSE
θ value	2.36792 (rank : 470)	NC score	0.297469 (rank : 252)
Query Neighborhood Hits	600	Target Neighborhood Hits	247	Shared Neighborhood Hits	172
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

ZN565_HUMAN
θ value	2.36792 (rank : 471)	NC score	-0.005542 (rank : 1201)
Query Neighborhood Hits	600	Target Neighborhood Hits	743	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N9K5, Q6NUS2	Gene names	ZNF565
Domain Architecture	No domain graphic available
Description	Zinc finger protein 565.

ABLM2_HUMAN
θ value	3.0926 (rank : 472)	NC score	0.003995 (rank : 1157)
Query Neighborhood Hits	600	Target Neighborhood Hits	317	Shared Neighborhood Hits	26
SwissProt Accessions	Q6H8Q1, Q6H8Q0, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7	Gene names	ABLIM2, KIAA1808
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

BMPER_MOUSE
θ value	3.0926 (rank : 473)	NC score	0.138595 (rank : 562)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

COMP_HUMAN
θ value	3.0926 (rank : 474)	NC score	0.303051 (rank : 245)
Query Neighborhood Hits	600	Target Neighborhood Hits	258	Shared Neighborhood Hits	180
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CT195_MOUSE
θ value	3.0926 (rank : 475)	NC score	0.035817 (rank : 1084)
Query Neighborhood Hits	600	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q80WB0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf195 homolog.

FBXL6_MOUSE
θ value	3.0926 (rank : 476)	NC score	0.006794 (rank : 1143)
Query Neighborhood Hits	600	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

KR108_HUMAN
θ value	3.0926 (rank : 477)	NC score	0.285786 (rank : 266)
Query Neighborhood Hits	600	Target Neighborhood Hits	226	Shared Neighborhood Hits	129
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR18_HUMAN
θ value	3.0926 (rank : 478)	NC score	-0.004630 (rank : 1199)
Query Neighborhood Hits	600	Target Neighborhood Hits	763	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HCG1, Q96JC5, Q9H7N6	Gene names	KIAA1611
Domain Architecture
Description	Zinc finger protein Kr18 (HKr18).

LRP4_MOUSE
θ value	3.0926 (rank : 479)	NC score	0.213086 (rank : 376)
Query Neighborhood Hits	600	Target Neighborhood Hits	351	Shared Neighborhood Hits	182
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

MT1E_HUMAN
θ value	3.0926 (rank : 480)	NC score	0.103784 (rank : 681)
Query Neighborhood Hits	600	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

NFX1_HUMAN
θ value	3.0926 (rank : 481)	NC score	0.212836 (rank : 377)
Query Neighborhood Hits	600	Target Neighborhood Hits	405	Shared Neighborhood Hits	140
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

OXSM_HUMAN
θ value	3.0926 (rank : 482)	NC score	0.008743 (rank : 1138)
Query Neighborhood Hits	600	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWU1	Gene names	OXSM
Domain Architecture	No domain graphic available
Description	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial precursor (EC 2.3.1.41) (Beta-ketoacyl synthase).

ROBO4_MOUSE
θ value	3.0926 (rank : 483)	NC score	0.270126 (rank : 296)
Query Neighborhood Hits	600	Target Neighborhood Hits	358	Shared Neighborhood Hits	109
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

SHBG_HUMAN
θ value	3.0926 (rank : 484)	NC score	0.186825 (rank : 431)
Query Neighborhood Hits	600	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

THYG_HUMAN
θ value	3.0926 (rank : 485)	NC score	0.055432 (rank : 995)
Query Neighborhood Hits	600	Target Neighborhood Hits	154	Shared Neighborhood Hits	82
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

THYG_MOUSE
θ value	3.0926 (rank : 486)	NC score	0.042919 (rank : 1076)
Query Neighborhood Hits	600	Target Neighborhood Hits	161	Shared Neighborhood Hits	80
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TNR11_MOUSE
θ value	3.0926 (rank : 487)	NC score	0.092759 (rank : 737)
Query Neighborhood Hits	600	Target Neighborhood Hits	121	Shared Neighborhood Hits	69
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR19_MOUSE
θ value	3.0926 (rank : 488)	NC score	0.121534 (rank : 623)
Query Neighborhood Hits	600	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

ZDHC8_HUMAN
θ value	3.0926 (rank : 489)	NC score	0.007223 (rank : 1142)
Query Neighborhood Hits	600	Target Neighborhood Hits	234	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

ZN11B_HUMAN
θ value	3.0926 (rank : 490)	NC score	-0.004476 (rank : 1197)
Query Neighborhood Hits	600	Target Neighborhood Hits	802	Shared Neighborhood Hits	37
SwissProt Accessions	Q06732, Q86XY8, Q8NDW3	Gene names	ZNF11B
Domain Architecture	No domain graphic available
Description	Zinc finger protein 11B.

ZN195_HUMAN
θ value	3.0926 (rank : 491)	NC score	-0.003692 (rank : 1189)
Query Neighborhood Hits	600	Target Neighborhood Hits	760	Shared Neighborhood Hits	37
SwissProt Accessions	O14628	Gene names	ZNF195, ZNFP104
Domain Architecture
Description	Zinc finger protein 195.

ZN226_HUMAN
θ value	3.0926 (rank : 492)	NC score	-0.001681 (rank : 1180)
Query Neighborhood Hits	600	Target Neighborhood Hits	770	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NYT6, Q96TE6, Q9NS44	Gene names	ZNF226
Domain Architecture
Description	Zinc finger protein 226.

ZN642_HUMAN
θ value	3.0926 (rank : 493)	NC score	-0.006285 (rank : 1205)
Query Neighborhood Hits	600	Target Neighborhood Hits	744	Shared Neighborhood Hits	31
SwissProt Accessions	Q49AA0, Q5SWM5, Q6ZWK8	Gene names	ZNF642
Domain Architecture	No domain graphic available
Description	Zinc finger protein 642.

ADAM9_HUMAN
θ value	4.03905 (rank : 494)	NC score	0.063673 (rank : 924)
Query Neighborhood Hits	600	Target Neighborhood Hits	243	Shared Neighborhood Hits	131
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

CAD23_MOUSE
θ value	4.03905 (rank : 495)	NC score	0.038502 (rank : 1082)
Query Neighborhood Hits	600	Target Neighborhood Hits	208	Shared Neighborhood Hits	25
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

FANK1_HUMAN
θ value	4.03905 (rank : 496)	NC score	0.046647 (rank : 1071)
Query Neighborhood Hits	600	Target Neighborhood Hits	326	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

KRA93_HUMAN
θ value	4.03905 (rank : 497)	NC score	0.235139 (rank : 342)
Query Neighborhood Hits	600	Target Neighborhood Hits	203	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

LCE5A_HUMAN
θ value	4.03905 (rank : 498)	NC score	0.089795 (rank : 764)
Query Neighborhood Hits	600	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LEPR_HUMAN
θ value	4.03905 (rank : 499)	NC score	0.099701 (rank : 698)
Query Neighborhood Hits	600	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

MGR1_HUMAN
θ value	4.03905 (rank : 500)	NC score	0.001791 (rank : 1168)
Query Neighborhood Hits	600	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MOT4_MOUSE
θ value	4.03905 (rank : 501)	NC score	0.002736 (rank : 1163)
Query Neighborhood Hits	600	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P57787, Q9ES80, Q9ESF8	Gene names	Slc16a3, Mct4
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3).

MUC5B_HUMAN
θ value	4.03905 (rank : 502)	NC score	0.212326 (rank : 380)
Query Neighborhood Hits	600	Target Neighborhood Hits	1020	Shared Neighborhood Hits	249
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYBPH_HUMAN
θ value	4.03905 (rank : 503)	NC score	0.201065 (rank : 399)
Query Neighborhood Hits	600	Target Neighborhood Hits	256	Shared Neighborhood Hits	109
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NACAM_MOUSE
θ value	4.03905 (rank : 504)	NC score	0.030431 (rank : 1094)
Query Neighborhood Hits	600	Target Neighborhood Hits	1866	Shared Neighborhood Hits	87
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SMS2_MOUSE
θ value	4.03905 (rank : 505)	NC score	0.008410 (rank : 1140)
Query Neighborhood Hits	600	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D4B1	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

TLN2_HUMAN
θ value	4.03905 (rank : 506)	NC score	0.006223 (rank : 1145)
Query Neighborhood Hits	600	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TNR11_HUMAN
θ value	4.03905 (rank : 507)	NC score	0.104057 (rank : 680)
Query Neighborhood Hits	600	Target Neighborhood Hits	135	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR5_MOUSE
θ value	4.03905 (rank : 508)	NC score	0.119691 (rank : 625)
Query Neighborhood Hits	600	Target Neighborhood Hits	131	Shared Neighborhood Hits	84
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TRI18_HUMAN
θ value	4.03905 (rank : 509)	NC score	0.019364 (rank : 1119)
Query Neighborhood Hits	600	Target Neighborhood Hits	307	Shared Neighborhood Hits	41
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

VEGFC_HUMAN
θ value	4.03905 (rank : 510)	NC score	0.118225 (rank : 630)
Query Neighborhood Hits	600	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ZDHC8_MOUSE
θ value	4.03905 (rank : 511)	NC score	0.005103 (rank : 1152)
Query Neighborhood Hits	600	Target Neighborhood Hits	243	Shared Neighborhood Hits	17
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ZN363_HUMAN
θ value	4.03905 (rank : 512)	NC score	0.034147 (rank : 1087)
Query Neighborhood Hits	600	Target Neighborhood Hits	162	Shared Neighborhood Hits	27
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

ALDR_HUMAN
θ value	5.27518 (rank : 513)	NC score	0.000844 (rank : 1172)
Query Neighborhood Hits	600	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P15121, Q9BS21, Q9UCI9	Gene names	AKR1B1, ALDR1
Domain Architecture
Description	Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).

EP300_HUMAN
θ value	5.27518 (rank : 514)	NC score	0.010837 (rank : 1131)
Query Neighborhood Hits	600	Target Neighborhood Hits	821	Shared Neighborhood Hits	41
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FUT7_HUMAN
θ value	5.27518 (rank : 515)	NC score	0.003343 (rank : 1161)
Query Neighborhood Hits	600	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q11130, Q6DK54	Gene names	FUT7
Domain Architecture
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 7) (FUCT-VII) (Selectin-ligand synthase).

GP110_HUMAN
θ value	5.27518 (rank : 516)	NC score	0.032546 (rank : 1088)
Query Neighborhood Hits	600	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

HABP2_MOUSE
θ value	5.27518 (rank : 517)	NC score	0.176458 (rank : 464)
Query Neighborhood Hits	600	Target Neighborhood Hits	445	Shared Neighborhood Hits	190
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HB2B_HUMAN
θ value	5.27518 (rank : 518)	NC score	-0.004318 (rank : 1195)
Query Neighborhood Hits	600	Target Neighborhood Hits	209	Shared Neighborhood Hits	5
SwissProt Accessions	P01912	Gene names
Domain Architecture
Description	HLA class II histocompatibility antigen, DR-1 beta chain precursor (Clone P2-beta-3).

LRP12_MOUSE
θ value	5.27518 (rank : 519)	NC score	0.077749 (rank : 842)
Query Neighborhood Hits	600	Target Neighborhood Hits	180	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP6_HUMAN
θ value	5.27518 (rank : 520)	NC score	0.098952 (rank : 705)
Query Neighborhood Hits	600	Target Neighborhood Hits	235	Shared Neighborhood Hits	99
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MAP1A_HUMAN
θ value	5.27518 (rank : 521)	NC score	-0.002771 (rank : 1183)
Query Neighborhood Hits	600	Target Neighborhood Hits	1626	Shared Neighborhood Hits	35
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MCPT2_MOUSE
θ value	5.27518 (rank : 522)	NC score	-0.003259 (rank : 1186)
Query Neighborhood Hits	600	Target Neighborhood Hits	175	Shared Neighborhood Hits	7
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

MGR4_HUMAN
θ value	5.27518 (rank : 523)	NC score	0.000417 (rank : 1175)
Query Neighborhood Hits	600	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MT1B_HUMAN
θ value	5.27518 (rank : 524)	NC score	0.128434 (rank : 594)
Query Neighborhood Hits	600	Target Neighborhood Hits	87	Shared Neighborhood Hits	59
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1X_HUMAN
θ value	5.27518 (rank : 525)	NC score	0.176736 (rank : 462)
Query Neighborhood Hits	600	Target Neighborhood Hits	76	Shared Neighborhood Hits	58
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT2_MOUSE
θ value	5.27518 (rank : 526)	NC score	0.141165 (rank : 559)
Query Neighborhood Hits	600	Target Neighborhood Hits	81	Shared Neighborhood Hits	59
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

PAPPA_HUMAN
θ value	5.27518 (rank : 527)	NC score	0.061049 (rank : 947)
Query Neighborhood Hits	600	Target Neighborhood Hits	161	Shared Neighborhood Hits	57
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PHF3_HUMAN
θ value	5.27518 (rank : 528)	NC score	0.002882 (rank : 1162)
Query Neighborhood Hits	600	Target Neighborhood Hits	419	Shared Neighborhood Hits	16
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PTN3_HUMAN
θ value	5.27518 (rank : 529)	NC score	0.071375 (rank : 870)
Query Neighborhood Hits	600	Target Neighborhood Hits	258	Shared Neighborhood Hits	28
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

RNC_HUMAN
θ value	5.27518 (rank : 530)	NC score	0.009300 (rank : 1135)
Query Neighborhood Hits	600	Target Neighborhood Hits	176	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

TFE2_MOUSE
θ value	5.27518 (rank : 531)	NC score	0.003903 (rank : 1158)
Query Neighborhood Hits	600	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

TICN1_MOUSE
θ value	5.27518 (rank : 532)	NC score	0.018253 (rank : 1121)
Query Neighborhood Hits	600	Target Neighborhood Hits	79	Shared Neighborhood Hits	14
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TMEM5_HUMAN
θ value	5.27518 (rank : 533)	NC score	0.007265 (rank : 1141)
Query Neighborhood Hits	600	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2B1, Q6PKD6	Gene names	TMEM5
Domain Architecture	No domain graphic available
Description	Transmembrane protein 5.

TNC6B_HUMAN
θ value	5.27518 (rank : 534)	NC score	0.013652 (rank : 1127)
Query Neighborhood Hits	600	Target Neighborhood Hits	256	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

TNR19_HUMAN
θ value	5.27518 (rank : 535)	NC score	0.090164 (rank : 761)
Query Neighborhood Hits	600	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TYRO_HUMAN
θ value	5.27518 (rank : 536)	NC score	0.034559 (rank : 1085)
Query Neighborhood Hits	600	Target Neighborhood Hits	35	Shared Neighborhood Hits	21
SwissProt Accessions	P14679, Q15675, Q15676, Q15680, Q8TAK4, Q9BYY0, Q9BZX1	Gene names	TYR
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Tumor rejection antigen AB) (SK29-AB) (LB24-AB).

TYRO_MOUSE
θ value	5.27518 (rank : 537)	NC score	0.027287 (rank : 1100)
Query Neighborhood Hits	600	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P11344	Gene names	Tyr
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Albino locus protein).

ULK2_HUMAN
θ value	5.27518 (rank : 538)	NC score	0.023426 (rank : 1106)
Query Neighborhood Hits	600	Target Neighborhood Hits	979	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

ZFP37_MOUSE
θ value	5.27518 (rank : 539)	NC score	-0.005873 (rank : 1203)
Query Neighborhood Hits	600	Target Neighborhood Hits	906	Shared Neighborhood Hits	34
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ZN221_HUMAN
θ value	5.27518 (rank : 540)	NC score	0.003821 (rank : 1159)
Query Neighborhood Hits	600	Target Neighborhood Hits	784	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UK13, Q9P1U8	Gene names	ZNF221
Domain Architecture
Description	Zinc finger protein 221.

ZN363_MOUSE
θ value	5.27518 (rank : 541)	NC score	0.012896 (rank : 1128)
Query Neighborhood Hits	600	Target Neighborhood Hits	134	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

ZN480_HUMAN
θ value	5.27518 (rank : 542)	NC score	-0.005940 (rank : 1204)
Query Neighborhood Hits	600	Target Neighborhood Hits	744	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WV37, Q5JPG9, Q6P0Q4, Q8N1M5	Gene names	ZNF480
Domain Architecture	No domain graphic available
Description	Zinc finger protein 480.

ASM3B_HUMAN
θ value	6.88961 (rank : 543)	NC score	0.003533 (rank : 1160)
Query Neighborhood Hits	600	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q92485, Q5T0Z0, Q96CB7	Gene names	SMPDL3B, ASML3B
Domain Architecture
Description	Acid sphingomyelinase-like phosphodiesterase 3b precursor (EC 3.1.4.-) (ASM-like phosphodiesterase 3b).

BRWD1_HUMAN
θ value	6.88961 (rank : 544)	NC score	-0.003910 (rank : 1192)
Query Neighborhood Hits	600	Target Neighborhood Hits	448	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CATE_MOUSE
θ value	6.88961 (rank : 545)	NC score	0.001438 (rank : 1171)
Query Neighborhood Hits	600	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P70269, O35647	Gene names	Ctse
Domain Architecture
Description	Cathepsin E precursor (EC 3.4.23.34).

CR2_MOUSE
θ value	6.88961 (rank : 546)	NC score	0.010941 (rank : 1130)
Query Neighborhood Hits	600	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

FANK1_MOUSE
θ value	6.88961 (rank : 547)	NC score	0.045249 (rank : 1073)
Query Neighborhood Hits	600	Target Neighborhood Hits	325	Shared Neighborhood Hits	52
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

FBLN3_HUMAN
θ value	6.88961 (rank : 548)	NC score	0.246140 (rank : 325)
Query Neighborhood Hits	600	Target Neighborhood Hits	293	Shared Neighborhood Hits	183
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FRMD6_MOUSE
θ value	6.88961 (rank : 549)	NC score	0.006484 (rank : 1144)
Query Neighborhood Hits	600	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

KLRA8_MOUSE
θ value	6.88961 (rank : 550)	NC score	0.001790 (rank : 1169)
Query Neighborhood Hits	600	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q60682, O78027	Gene names	Klra8, Ly-49h, Ly49-h, Ly49H
Domain Architecture
Description	Killer cell lectin-like receptor 8 (T-cell surface glycoprotein Ly- 49H) (Ly49-H antigen) (Lymphocyte antigen 49H).

KRHB3_HUMAN
θ value	6.88961 (rank : 551)	NC score	0.004672 (rank : 1154)
Query Neighborhood Hits	600	Target Neighborhood Hits	438	Shared Neighborhood Hits	29
SwissProt Accessions	P78385, Q9NSB3	Gene names	KRTHB3
Domain Architecture
Description	Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3).

LORI_MOUSE
θ value	6.88961 (rank : 552)	NC score	0.117199 (rank : 633)
Query Neighborhood Hits	600	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

MLL2_HUMAN
θ value	6.88961 (rank : 553)	NC score	0.021776 (rank : 1114)
Query Neighborhood Hits	600	Target Neighborhood Hits	1788	Shared Neighborhood Hits	88
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MT1I_HUMAN
θ value	6.88961 (rank : 554)	NC score	0.076229 (rank : 847)
Query Neighborhood Hits	600	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

POK7_HUMAN
θ value	6.88961 (rank : 555)	NC score	0.000468 (rank : 1174)
Query Neighborhood Hits	600	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QC07, Q6QAI9, Q96PI5	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K18 Pol protein) (HERV-K110 Pol protein) (HERV-K(C1a) Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H)].

PTPRR_MOUSE
θ value	6.88961 (rank : 556)	NC score	0.090885 (rank : 754)
Query Neighborhood Hits	600	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRZ_HUMAN
θ value	6.88961 (rank : 557)	NC score	0.111281 (rank : 651)
Query Neighborhood Hits	600	Target Neighborhood Hits	255	Shared Neighborhood Hits	52
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

RNAS2_MOUSE
θ value	6.88961 (rank : 558)	NC score	0.002531 (rank : 1165)
Query Neighborhood Hits	600	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	O35291	Gene names	Rnase2, Ear4
Domain Architecture
Description	Nonsecretory ribonuclease precursor (EC 3.1.27.5) (Eosinophil cationic-type ribonuclease 4) (MR-4) (Ribonuclease 2).

SN_MOUSE
θ value	6.88961 (rank : 559)	NC score	0.190916 (rank : 419)
Query Neighborhood Hits	600	Target Neighborhood Hits	416	Shared Neighborhood Hits	90
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

ST18_MOUSE
θ value	6.88961 (rank : 560)	NC score	0.020391 (rank : 1115)
Query Neighborhood Hits	600	Target Neighborhood Hits	248	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TY4, Q3UH00, Q3URH9, Q3UVB9, Q3UZN9, Q811B4, Q8K098	Gene names	St18, Kiaa0535
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18.

SYPM_MOUSE
θ value	6.88961 (rank : 561)	NC score	0.005658 (rank : 1148)
Query Neighborhood Hits	600	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFI5, Q8R0C4	Gene names	Pars2
Domain Architecture	No domain graphic available
Description	Probable prolyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.15) (Proline--tRNA ligase) (ProRS).

TBX18_MOUSE
θ value	6.88961 (rank : 562)	NC score	-0.000672 (rank : 1177)
Query Neighborhood Hits	600	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TCF17_HUMAN
θ value	6.88961 (rank : 563)	NC score	-0.003051 (rank : 1184)
Query Neighborhood Hits	600	Target Neighborhood Hits	797	Shared Neighborhood Hits	46
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

TLN2_MOUSE
θ value	6.88961 (rank : 564)	NC score	0.006166 (rank : 1146)
Query Neighborhood Hits	600	Target Neighborhood Hits	149	Shared Neighborhood Hits	11
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TNR3_MOUSE
θ value	6.88961 (rank : 565)	NC score	0.133316 (rank : 574)
Query Neighborhood Hits	600	Target Neighborhood Hits	113	Shared Neighborhood Hits	74
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TRIM9_HUMAN
θ value	6.88961 (rank : 566)	NC score	0.047516 (rank : 1070)
Query Neighborhood Hits	600	Target Neighborhood Hits	294	Shared Neighborhood Hits	54
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

UBP36_HUMAN
θ value	6.88961 (rank : 567)	NC score	0.002331 (rank : 1166)
Query Neighborhood Hits	600	Target Neighborhood Hits	232	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

WNK1_MOUSE
θ value	6.88961 (rank : 568)	NC score	0.019575 (rank : 1118)
Query Neighborhood Hits	600	Target Neighborhood Hits	1179	Shared Neighborhood Hits	69
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

WNT16_MOUSE
θ value	6.88961 (rank : 569)	NC score	-0.001530 (rank : 1179)
Query Neighborhood Hits	600	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYS1	Gene names	Wnt16
Domain Architecture
Description	Protein Wnt-16 precursor.

4ET_MOUSE
θ value	8.99809 (rank : 570)	NC score	0.005657 (rank : 1149)
Query Neighborhood Hits	600	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

ADA11_MOUSE
θ value	8.99809 (rank : 571)	NC score	0.090533 (rank : 758)
Query Neighborhood Hits	600	Target Neighborhood Hits	263	Shared Neighborhood Hits	153
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA21_HUMAN
θ value	8.99809 (rank : 572)	NC score	0.038130 (rank : 1083)
Query Neighborhood Hits	600	Target Neighborhood Hits	181	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA30_HUMAN
θ value	8.99809 (rank : 573)	NC score	0.041401 (rank : 1078)
Query Neighborhood Hits	600	Target Neighborhood Hits	391	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADM1B_MOUSE
θ value	8.99809 (rank : 574)	NC score	0.042060 (rank : 1077)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	109
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ANK3_HUMAN
θ value	8.99809 (rank : 575)	NC score	0.020204 (rank : 1116)
Query Neighborhood Hits	600	Target Neighborhood Hits	853	Shared Neighborhood Hits	39
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ATS2_MOUSE
θ value	8.99809 (rank : 576)	NC score	0.004811 (rank : 1153)
Query Neighborhood Hits	600	Target Neighborhood Hits	179	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

CASZ1_HUMAN
θ value	8.99809 (rank : 577)	NC score	0.005589 (rank : 1150)
Query Neighborhood Hits	600	Target Neighborhood Hits	473	Shared Neighborhood Hits	25
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

CO8B_MOUSE
θ value	8.99809 (rank : 578)	NC score	0.089282 (rank : 769)
Query Neighborhood Hits	600	Target Neighborhood Hits	224	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CORIN_MOUSE
θ value	8.99809 (rank : 579)	NC score	0.090334 (rank : 760)
Query Neighborhood Hits	600	Target Neighborhood Hits	451	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

DBNL_MOUSE
θ value	8.99809 (rank : 580)	NC score	-0.001101 (rank : 1178)
Query Neighborhood Hits	600	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

DEN1A_MOUSE
θ value	8.99809 (rank : 581)	NC score	0.004165 (rank : 1156)
Query Neighborhood Hits	600	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

FBLI1_MOUSE
θ value	8.99809 (rank : 582)	NC score	0.002603 (rank : 1164)
Query Neighborhood Hits	600	Target Neighborhood Hits	228	Shared Neighborhood Hits	14
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

FBLN5_HUMAN
θ value	8.99809 (rank : 583)	NC score	0.263104 (rank : 300)
Query Neighborhood Hits	600	Target Neighborhood Hits	329	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FOG2_HUMAN
θ value	8.99809 (rank : 584)	NC score	-0.003793 (rank : 1191)
Query Neighborhood Hits	600	Target Neighborhood Hits	731	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WW38, Q9NPL7, Q9NPS4, Q9UNI5	Gene names	ZFPM2, FOG2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (FOG-2) (hFOG-2).

FOG2_MOUSE
θ value	8.99809 (rank : 585)	NC score	-0.003757 (rank : 1190)
Query Neighborhood Hits	600	Target Neighborhood Hits	714	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

KRA45_HUMAN
θ value	8.99809 (rank : 586)	NC score	0.236805 (rank : 338)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

MT2_HUMAN
θ value	8.99809 (rank : 587)	NC score	0.078008 (rank : 839)
Query Neighborhood Hits	600	Target Neighborhood Hits	69	Shared Neighborhood Hits	49
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MUC18_HUMAN
θ value	8.99809 (rank : 588)	NC score	0.187763 (rank : 427)
Query Neighborhood Hits	600	Target Neighborhood Hits	275	Shared Neighborhood Hits	81
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

PCDH8_HUMAN
θ value	8.99809 (rank : 589)	NC score	0.024199 (rank : 1105)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	O95206, Q8IYE9, Q96SF1	Gene names	PCDH8
Domain Architecture
Description	Protocadherin-8 precursor (Arcadlin).

PRDM5_MOUSE
θ value	8.99809 (rank : 590)	NC score	-0.006776 (rank : 1206)
Query Neighborhood Hits	600	Target Neighborhood Hits	774	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CXE0	Gene names	Prdm5
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 5 (PR domain-containing protein 5).

RAG2_HUMAN
θ value	8.99809 (rank : 591)	NC score	0.004256 (rank : 1155)
Query Neighborhood Hits	600	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P55895, Q8TBL4	Gene names	RAG2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

RIMB1_HUMAN
θ value	8.99809 (rank : 592)	NC score	0.031747 (rank : 1091)
Query Neighborhood Hits	600	Target Neighborhood Hits	1479	Shared Neighborhood Hits	56
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SPY2_HUMAN
θ value	8.99809 (rank : 593)	NC score	0.025467 (rank : 1104)
Query Neighborhood Hits	600	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SRGEF_HUMAN
θ value	8.99809 (rank : 594)	NC score	0.000817 (rank : 1173)
Query Neighborhood Hits	600	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

TICN1_HUMAN
θ value	8.99809 (rank : 595)	NC score	0.017577 (rank : 1123)
Query Neighborhood Hits	600	Target Neighborhood Hits	70	Shared Neighborhood Hits	15
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TNR1B_HUMAN
θ value	8.99809 (rank : 596)	NC score	0.087737 (rank : 784)
Query Neighborhood Hits	600	Target Neighborhood Hits	127	Shared Neighborhood Hits	71
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

VMDL3_MOUSE
θ value	8.99809 (rank : 597)	NC score	0.001569 (rank : 1170)
Query Neighborhood Hits	600	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q6H1V1	Gene names	Vmd2l3
Domain Architecture	No domain graphic available
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

ZN228_HUMAN
θ value	8.99809 (rank : 598)	NC score	-0.003055 (rank : 1185)
Query Neighborhood Hits	600	Target Neighborhood Hits	775	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UJU3, Q9HCA7	Gene names	ZNF228
Domain Architecture
Description	Zinc finger protein 228.

ZN700_HUMAN
θ value	8.99809 (rank : 599)	NC score	-0.004087 (rank : 1193)
Query Neighborhood Hits	600	Target Neighborhood Hits	772	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H0M5	Gene names	ZNF700
Domain Architecture	No domain graphic available
Description	Zinc finger protein 700.

ZNF14_HUMAN
θ value	8.99809 (rank : 600)	NC score	-0.005601 (rank : 1202)
Query Neighborhood Hits	600	Target Neighborhood Hits	760	Shared Neighborhood Hits	35
SwissProt Accessions	P17017, Q9ULZ5	Gene names	ZNF14, GIOT4, KOX6
Domain Architecture
Description	Zinc finger protein 14 (Zinc finger protein KOX6) (Gonadotropin- inducible transcription repressor 4) (GIOT-4).

AATK_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.055142 (rank : 999)
Query Neighborhood Hits	600	Target Neighborhood Hits	1243	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AATK_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.057281 (rank : 987)
Query Neighborhood Hits	600	Target Neighborhood Hits	942	Shared Neighborhood Hits	61
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ABL1_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.051371 (rank : 1056)
Query Neighborhood Hits	600	Target Neighborhood Hits	1220	Shared Neighborhood Hits	62
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.052008 (rank : 1041)
Query Neighborhood Hits	600	Target Neighborhood Hits	1178	Shared Neighborhood Hits	64
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL2_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.051260 (rank : 1058)
Query Neighborhood Hits	600	Target Neighborhood Hits	1045	Shared Neighborhood Hits	59
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ACK1_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.058620 (rank : 979)
Query Neighborhood Hits	600	Target Neighborhood Hits	1140	Shared Neighborhood Hits	64
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.059195 (rank : 972)
Query Neighborhood Hits	600	Target Neighborhood Hits	1080	Shared Neighborhood Hits	62
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ADA10_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.066148 (rank : 913)
Query Neighborhood Hits	600	Target Neighborhood Hits	189	Shared Neighborhood Hits	96
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.059948 (rank : 958)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	93
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA15_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.084647 (rank : 803)
Query Neighborhood Hits	600	Target Neighborhood Hits	288	Shared Neighborhood Hits	143
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.085628 (rank : 798)
Query Neighborhood Hits	600	Target Neighborhood Hits	324	Shared Neighborhood Hits	158
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.054128 (rank : 1008)
Query Neighborhood Hits	600	Target Neighborhood Hits	223	Shared Neighborhood Hits	101
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA18_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.060459 (rank : 953)
Query Neighborhood Hits	600	Target Neighborhood Hits	227	Shared Neighborhood Hits	124
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA19_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.066097 (rank : 915)
Query Neighborhood Hits	600	Target Neighborhood Hits	381	Shared Neighborhood Hits	140
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA19_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.068536 (rank : 897)
Query Neighborhood Hits	600	Target Neighborhood Hits	315	Shared Neighborhood Hits	149
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADA23_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.074369 (rank : 853)
Query Neighborhood Hits	600	Target Neighborhood Hits	235	Shared Neighborhood Hits	134
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.071022 (rank : 875)
Query Neighborhood Hits	600	Target Neighborhood Hits	245	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA25_MOUSE
θ value	θ > 10 (rank : 618)	NC score	0.051871 (rank : 1044)
Query Neighborhood Hits	600	Target Neighborhood Hits	213	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADA28_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.053013 (rank : 1027)
Query Neighborhood Hits	600	Target Neighborhood Hits	241	Shared Neighborhood Hits	121
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA33_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.066107 (rank : 914)
Query Neighborhood Hits	600	Target Neighborhood Hits	264	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.059496 (rank : 966)
Query Neighborhood Hits	600	Target Neighborhood Hits	231	Shared Neighborhood Hits	126
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.061332 (rank : 945)
Query Neighborhood Hits	600	Target Neighborhood Hits	209	Shared Neighborhood Hits	116
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM7_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.059666 (rank : 962)
Query Neighborhood Hits	600	Target Neighborhood Hits	221	Shared Neighborhood Hits	125
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM8_MOUSE
θ value	θ > 10 (rank : 624)	NC score	0.081010 (rank : 824)
Query Neighborhood Hits	600	Target Neighborhood Hits	326	Shared Neighborhood Hits	149
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.069989 (rank : 883)
Query Neighborhood Hits	600	Target Neighborhood Hits	325	Shared Neighborhood Hits	150
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADM1A_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.050410 (rank : 1064)
Query Neighborhood Hits	600	Target Neighborhood Hits	230	Shared Neighborhood Hits	120
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ALK_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.068922 (rank : 894)
Query Neighborhood Hits	600	Target Neighborhood Hits	795	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.069631 (rank : 886)
Query Neighborhood Hits	600	Target Neighborhood Hits	811	Shared Neighborhood Hits	73
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ANKF1_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.098979 (rank : 704)
Query Neighborhood Hits	600	Target Neighborhood Hits	126	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

APR3_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.072469 (rank : 866)
Query Neighborhood Hits	600	Target Neighborhood Hits	50	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.084557 (rank : 805)
Query Neighborhood Hits	600	Target Neighborhood Hits	61	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ASTN_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.055287 (rank : 996)
Query Neighborhood Hits	600	Target Neighborhood Hits	105	Shared Neighborhood Hits	51
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.057646 (rank : 984)
Query Neighborhood Hits	600	Target Neighborhood Hits	98	Shared Neighborhood Hits	51
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATL3_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.137912 (rank : 563)
Query Neighborhood Hits	600	Target Neighborhood Hits	414	Shared Neighborhood Hits	118
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

BASI_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.175884 (rank : 466)
Query Neighborhood Hits	600	Target Neighborhood Hits	211	Shared Neighborhood Hits	72
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

BASI_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.168750 (rank : 483)
Query Neighborhood Hits	600	Target Neighborhood Hits	238	Shared Neighborhood Hits	76
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

BLK_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.051835 (rank : 1047)
Query Neighborhood Hits	600	Target Neighborhood Hits	994	Shared Neighborhood Hits	54
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.052569 (rank : 1033)
Query Neighborhood Hits	600	Target Neighborhood Hits	992	Shared Neighborhood Hits	55
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BMP1_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.066474 (rank : 912)
Query Neighborhood Hits	600	Target Neighborhood Hits	233	Shared Neighborhood Hits	100
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.067020 (rank : 908)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	101
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMPER_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.123690 (rank : 610)
Query Neighborhood Hits	600	Target Neighborhood Hits	175	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMX_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.052423 (rank : 1036)
Query Neighborhood Hits	600	Target Neighborhood Hits	942	Shared Neighborhood Hits	55
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.052879 (rank : 1028)
Query Neighborhood Hits	600	Target Neighborhood Hits	912	Shared Neighborhood Hits	54
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BTC_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.051184 (rank : 1059)
Query Neighborhood Hits	600	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

BTC_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.050511 (rank : 1063)
Query Neighborhood Hits	600	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

BTK_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.052284 (rank : 1038)
Query Neighborhood Hits	600	Target Neighborhood Hits	1026	Shared Neighborhood Hits	58
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.052331 (rank : 1037)
Query Neighborhood Hits	600	Target Neighborhood Hits	1017	Shared Neighborhood Hits	58
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

C1QR1_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.283206 (rank : 271)
Query Neighborhood Hits	600	Target Neighborhood Hits	493	Shared Neighborhood Hits	213
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.279840 (rank : 277)
Query Neighborhood Hits	600	Target Neighborhood Hits	342	Shared Neighborhood Hits	195
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD166_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.118865 (rank : 627)
Query Neighborhood Hits	600	Target Neighborhood Hits	247	Shared Neighborhood Hits	68
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

CD166_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.131010 (rank : 583)
Query Neighborhood Hits	600	Target Neighborhood Hits	252	Shared Neighborhood Hits	71
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

CD22_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.166457 (rank : 491)
Query Neighborhood Hits	600	Target Neighborhood Hits	365	Shared Neighborhood Hits	82
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD22_MOUSE
θ value	θ > 10 (rank : 653)	NC score	0.177282 (rank : 458)
Query Neighborhood Hits	600	Target Neighborhood Hits	331	Shared Neighborhood Hits	76
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD248_HUMAN
θ value	θ > 10 (rank : 654)	NC score	0.216315 (rank : 374)
Query Neighborhood Hits	600	Target Neighborhood Hits	679	Shared Neighborhood Hits	175
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 655)	NC score	0.208569 (rank : 389)
Query Neighborhood Hits	600	Target Neighborhood Hits	578	Shared Neighborhood Hits	159
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD276_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.099339 (rank : 700)
Query Neighborhood Hits	600	Target Neighborhood Hits	261	Shared Neighborhood Hits	51
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	θ > 10 (rank : 657)	NC score	0.062101 (rank : 937)
Query Neighborhood Hits	600	Target Neighborhood Hits	243	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CD320_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.082207 (rank : 814)
Query Neighborhood Hits	600	Target Neighborhood Hits	103	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD79A_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.062219 (rank : 936)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.233129 (rank : 346)
Query Neighborhood Hits	600	Target Neighborhood Hits	353	Shared Neighborhood Hits	174
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 661)	NC score	0.179019 (rank : 453)
Query Neighborhood Hits	600	Target Neighborhood Hits	295	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CEA20_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.154715 (rank : 521)
Query Neighborhood Hits	600	Target Neighborhood Hits	251	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

CEAM1_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.135553 (rank : 569)
Query Neighborhood Hits	600	Target Neighborhood Hits	348	Shared Neighborhood Hits	80
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

CEAM1_MOUSE
θ value	θ > 10 (rank : 664)	NC score	0.152914 (rank : 528)
Query Neighborhood Hits	600	Target Neighborhood Hits	326	Shared Neighborhood Hits	79
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

CEAM5_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.165045 (rank : 498)
Query Neighborhood Hits	600	Target Neighborhood Hits	343	Shared Neighborhood Hits	85
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

CEAM6_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.114028 (rank : 643)
Query Neighborhood Hits	600	Target Neighborhood Hits	308	Shared Neighborhood Hits	81
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

CEAM7_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.060771 (rank : 949)
Query Neighborhood Hits	600	Target Neighborhood Hits	170	Shared Neighborhood Hits	60
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

CEAM8_HUMAN
θ value	θ > 10 (rank : 668)	NC score	0.098699 (rank : 706)
Query Neighborhood Hits	600	Target Neighborhood Hits	264	Shared Neighborhood Hits	77
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

CFC1_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.202015 (rank : 397)
Query Neighborhood Hits	600	Target Neighborhood Hits	148	Shared Neighborhood Hits	111
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 670)	NC score	0.181109 (rank : 451)
Query Neighborhood Hits	600	Target Neighborhood Hits	125	Shared Neighborhood Hits	96
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CHRD_HUMAN
θ value	θ > 10 (rank : 671)	NC score	0.073409 (rank : 856)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 672)	NC score	0.081849 (rank : 820)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CI094_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.180382 (rank : 452)
Query Neighborhood Hits	600	Target Neighborhood Hits	310	Shared Neighborhood Hits	92
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CILP1_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.105523 (rank : 676)
Query Neighborhood Hits	600	Target Neighborhood Hits	266	Shared Neighborhood Hits	96
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.100987 (rank : 691)
Query Neighborhood Hits	600	Target Neighborhood Hits	282	Shared Neighborhood Hits	88
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP2_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.125346 (rank : 601)
Query Neighborhood Hits	600	Target Neighborhood Hits	307	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CLC14_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.060585 (rank : 951)
Query Neighborhood Hits	600	Target Neighborhood Hits	143	Shared Neighborhood Hits	65
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.062782 (rank : 931)
Query Neighborhood Hits	600	Target Neighborhood Hits	120	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CO6_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.126033 (rank : 597)
Query Neighborhood Hits	600	Target Neighborhood Hits	331	Shared Neighborhood Hits	132
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.093917 (rank : 730)
Query Neighborhood Hits	600	Target Neighborhood Hits	278	Shared Neighborhood Hits	115
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.060054 (rank : 956)
Query Neighborhood Hits	600	Target Neighborhood Hits	200	Shared Neighborhood Hits	85
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	θ > 10 (rank : 682)	NC score	0.052053 (rank : 1040)
Query Neighborhood Hits	600	Target Neighborhood Hits	182	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.059174 (rank : 973)
Query Neighborhood Hits	600	Target Neighborhood Hits	199	Shared Neighborhood Hits	75
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.061650 (rank : 941)
Query Neighborhood Hits	600	Target Neighborhood Hits	147	Shared Neighborhood Hits	68
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.063243 (rank : 928)
Query Neighborhood Hits	600	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CRAC1_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.066880 (rank : 910)
Query Neighborhood Hits	600	Target Neighborhood Hits	111	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 687)	NC score	0.068810 (rank : 895)
Query Neighborhood Hits	600	Target Neighborhood Hits	112	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CSF1R_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.088583 (rank : 777)
Query Neighborhood Hits	600	Target Neighborhood Hits	943	Shared Neighborhood Hits	110
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSF1R_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.109829 (rank : 658)
Query Neighborhood Hits	600	Target Neighborhood Hits	983	Shared Neighborhood Hits	116
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSK_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.050879 (rank : 1062)
Query Neighborhood Hits	600	Target Neighborhood Hits	1009	Shared Neighborhood Hits	58
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSPG2_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.234027 (rank : 343)
Query Neighborhood Hits	600	Target Neighborhood Hits	681	Shared Neighborhood Hits	205
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 692)	NC score	0.232611 (rank : 349)
Query Neighborhood Hits	600	Target Neighborhood Hits	711	Shared Neighborhood Hits	201
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG4_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.125140 (rank : 602)
Query Neighborhood Hits	600	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CT127_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.132126 (rank : 577)
Query Neighborhood Hits	600	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CXAR_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.097288 (rank : 712)
Query Neighborhood Hits	600	Target Neighborhood Hits	245	Shared Neighborhood Hits	58
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

CXAR_MOUSE
θ value	θ > 10 (rank : 696)	NC score	0.091283 (rank : 749)
Query Neighborhood Hits	600	Target Neighborhood Hits	250	Shared Neighborhood Hits	60
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

CYR61_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.053566 (rank : 1021)
Query Neighborhood Hits	600	Target Neighborhood Hits	159	Shared Neighborhood Hits	61
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 698)	NC score	0.054060 (rank : 1011)
Query Neighborhood Hits	600	Target Neighborhood Hits	156	Shared Neighborhood Hits	60
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DDR1_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.072306 (rank : 868)
Query Neighborhood Hits	600	Target Neighborhood Hits	819	Shared Neighborhood Hits	64
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 700)	NC score	0.071141 (rank : 873)
Query Neighborhood Hits	600	Target Neighborhood Hits	818	Shared Neighborhood Hits	64
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.071989 (rank : 869)
Query Neighborhood Hits	600	Target Neighborhood Hits	818	Shared Neighborhood Hits	62
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 702)	NC score	0.071335 (rank : 871)
Query Neighborhood Hits	600	Target Neighborhood Hits	813	Shared Neighborhood Hits	63
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DKK3_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.058182 (rank : 980)
Query Neighborhood Hits	600	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.059520 (rank : 965)
Query Neighborhood Hits	600	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

EGFL7_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.299072 (rank : 249)
Query Neighborhood Hits	600	Target Neighborhood Hits	325	Shared Neighborhood Hits	190
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 706)	NC score	0.282939 (rank : 273)
Query Neighborhood Hits	600	Target Neighborhood Hits	287	Shared Neighborhood Hits	172
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.249373 (rank : 320)
Query Neighborhood Hits	600	Target Neighborhood Hits	270	Shared Neighborhood Hits	150
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 708)	NC score	0.245714 (rank : 327)
Query Neighborhood Hits	600	Target Neighborhood Hits	266	Shared Neighborhood Hits	153
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFR_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.076988 (rank : 845)
Query Neighborhood Hits	600	Target Neighborhood Hits	939	Shared Neighborhood Hits	127
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 710)	NC score	0.077172 (rank : 844)
Query Neighborhood Hits	600	Target Neighborhood Hits	927	Shared Neighborhood Hits	121
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EGF_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.248863 (rank : 321)
Query Neighborhood Hits	600	Target Neighborhood Hits	343	Shared Neighborhood Hits	193
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.277343 (rank : 279)
Query Neighborhood Hits	600	Target Neighborhood Hits	358	Shared Neighborhood Hits	202
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELTD1_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.148489 (rank : 540)
Query Neighborhood Hits	600	Target Neighborhood Hits	269	Shared Neighborhood Hits	132
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 714)	NC score	0.193212 (rank : 413)
Query Neighborhood Hits	600	Target Neighborhood Hits	288	Shared Neighborhood Hits	145
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMB_MOUSE
θ value	θ > 10 (rank : 715)	NC score	0.082076 (rank : 817)
Query Neighborhood Hits	600	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

EMR1_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.248018 (rank : 322)
Query Neighborhood Hits	600	Target Neighborhood Hits	382	Shared Neighborhood Hits	192
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 717)	NC score	0.219652 (rank : 367)
Query Neighborhood Hits	600	Target Neighborhood Hits	349	Shared Neighborhood Hits	163
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 718)	NC score	0.235649 (rank : 340)
Query Neighborhood Hits	600	Target Neighborhood Hits	345	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 719)	NC score	0.109331 (rank : 663)
Query Neighborhood Hits	600	Target Neighborhood Hits	245	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 720)	NC score	0.084414 (rank : 806)
Query Neighborhood Hits	600	Target Neighborhood Hits	191	Shared Neighborhood Hits	77
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

ERBB2_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.076165 (rank : 848)
Query Neighborhood Hits	600	Target Neighborhood Hits	1073	Shared Neighborhood Hits	117
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
θ value	θ > 10 (rank : 722)	NC score	0.073363 (rank : 857)
Query Neighborhood Hits	600	Target Neighborhood Hits	918	Shared Neighborhood Hits	104
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_MOUSE
θ value	θ > 10 (rank : 723)	NC score	0.079088 (rank : 833)
Query Neighborhood Hits	600	Target Neighborhood Hits	898	Shared Neighborhood Hits	105
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.081870 (rank : 819)
Query Neighborhood Hits	600	Target Neighborhood Hits	910	Shared Neighborhood Hits	115
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

EREG_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.067446 (rank : 903)
Query Neighborhood Hits	600	Target Neighborhood Hits	73	Shared Neighborhood Hits	44
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ESAM_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.099807 (rank : 696)
Query Neighborhood Hits	600	Target Neighborhood Hits	251	Shared Neighborhood Hits	70
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ESAM_MOUSE
θ value	θ > 10 (rank : 727)	NC score	0.087338 (rank : 788)
Query Neighborhood Hits	600	Target Neighborhood Hits	222	Shared Neighborhood Hits	62
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

FA10_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.105144 (rank : 677)
Query Neighborhood Hits	600	Target Neighborhood Hits	431	Shared Neighborhood Hits	168
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 729)	NC score	0.106760 (rank : 673)
Query Neighborhood Hits	600	Target Neighborhood Hits	435	Shared Neighborhood Hits	165
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA12_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.115425 (rank : 636)
Query Neighborhood Hits	600	Target Neighborhood Hits	425	Shared Neighborhood Hits	166
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 731)	NC score	0.096256 (rank : 715)
Query Neighborhood Hits	600	Target Neighborhood Hits	404	Shared Neighborhood Hits	155
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 732)	NC score	0.080877 (rank : 825)
Query Neighborhood Hits	600	Target Neighborhood Hits	374	Shared Neighborhood Hits	135
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.100221 (rank : 694)
Query Neighborhood Hits	600	Target Neighborhood Hits	421	Shared Neighborhood Hits	159
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FAK1_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.059613 (rank : 963)
Query Neighborhood Hits	600	Target Neighborhood Hits	850	Shared Neighborhood Hits	55
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 735)	NC score	0.059490 (rank : 967)
Query Neighborhood Hits	600	Target Neighborhood Hits	850	Shared Neighborhood Hits	55
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.060195 (rank : 954)
Query Neighborhood Hits	600	Target Neighborhood Hits	847	Shared Neighborhood Hits	54
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 737)	NC score	0.059758 (rank : 960)
Query Neighborhood Hits	600	Target Neighborhood Hits	851	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FBLN2_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.308352 (rank : 235)
Query Neighborhood Hits	600	Target Neighborhood Hits	392	Shared Neighborhood Hits	209
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 739)	NC score	0.298115 (rank : 250)
Query Neighborhood Hits	600	Target Neighborhood Hits	505	Shared Neighborhood Hits	217
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_MOUSE
θ value	θ > 10 (rank : 740)	NC score	0.229707 (rank : 355)
Query Neighborhood Hits	600	Target Neighborhood Hits	279	Shared Neighborhood Hits	166
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.258888 (rank : 308)
Query Neighborhood Hits	600	Target Neighborhood Hits	278	Shared Neighborhood Hits	175
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 742)	NC score	0.251840 (rank : 314)
Query Neighborhood Hits	600	Target Neighborhood Hits	270	Shared Neighborhood Hits	170
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_MOUSE
θ value	θ > 10 (rank : 743)	NC score	0.260034 (rank : 306)
Query Neighborhood Hits	600	Target Neighborhood Hits	317	Shared Neighborhood Hits	196
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FCERA_HUMAN
θ value	θ > 10 (rank : 744)	NC score	0.053471 (rank : 1022)
Query Neighborhood Hits	600	Target Neighborhood Hits	150	Shared Neighborhood Hits	44
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

FCGR1_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.055573 (rank : 994)
Query Neighborhood Hits	600	Target Neighborhood Hits	145	Shared Neighborhood Hits	45
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

FCN1_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.053769 (rank : 1014)
Query Neighborhood Hits	600	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	O00602, Q92596	Gene names	FCN1
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FCN1_MOUSE
θ value	θ > 10 (rank : 747)	NC score	0.054398 (rank : 1006)
Query Neighborhood Hits	600	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FCN2_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.053571 (rank : 1020)
Query Neighborhood Hits	600	Target Neighborhood Hits	122	Shared Neighborhood Hits	14
SwissProt Accessions	Q15485, Q9UC57	Gene names	FCN2
Domain Architecture
Description	Ficolin-2 precursor (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin B) (Serum lectin p35) (EBP-37) (Hucolin) (L- Ficolin).

FCN3_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.053679 (rank : 1016)
Query Neighborhood Hits	600	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

FCRL2_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.159902 (rank : 507)
Query Neighborhood Hits	600	Target Neighborhood Hits	251	Shared Neighborhood Hits	74
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

FCRL5_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.170964 (rank : 476)
Query Neighborhood Hits	600	Target Neighborhood Hits	267	Shared Neighborhood Hits	69
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

FER_HUMAN
θ value	θ > 10 (rank : 752)	NC score	0.054497 (rank : 1004)
Query Neighborhood Hits	600	Target Neighborhood Hits	1278	Shared Neighborhood Hits	60
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FES_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.055261 (rank : 997)
Query Neighborhood Hits	600	Target Neighborhood Hits	978	Shared Neighborhood Hits	56
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
θ value	θ > 10 (rank : 754)	NC score	0.055165 (rank : 998)
Query Neighborhood Hits	600	Target Neighborhood Hits	980	Shared Neighborhood Hits	54
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FGFR1_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.121983 (rank : 618)
Query Neighborhood Hits	600	Target Neighborhood Hits	1069	Shared Neighborhood Hits	125
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR1_MOUSE
θ value	θ > 10 (rank : 756)	NC score	0.121862 (rank : 619)
Query Neighborhood Hits	600	Target Neighborhood Hits	1068	Shared Neighborhood Hits	125
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

FGFR2_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.121638 (rank : 621)
Query Neighborhood Hits	600	Target Neighborhood Hits	1062	Shared Neighborhood Hits	124
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

FGFR2_MOUSE
θ value	θ > 10 (rank : 758)	NC score	0.117754 (rank : 631)
Query Neighborhood Hits	600	Target Neighborhood Hits	1062	Shared Neighborhood Hits	123
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

FGFR3_HUMAN
θ value	θ > 10 (rank : 759)	NC score	0.122035 (rank : 617)
Query Neighborhood Hits	600	Target Neighborhood Hits	1042	Shared Neighborhood Hits	124
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

FGFR3_MOUSE
θ value	θ > 10 (rank : 760)	NC score	0.124828 (rank : 606)
Query Neighborhood Hits	600	Target Neighborhood Hits	1059	Shared Neighborhood Hits	126
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

FGFR4_HUMAN
θ value	θ > 10 (rank : 761)	NC score	0.125754 (rank : 599)
Query Neighborhood Hits	600	Target Neighborhood Hits	1037	Shared Neighborhood Hits	125
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

FGFR4_MOUSE
θ value	θ > 10 (rank : 762)	NC score	0.128768 (rank : 592)
Query Neighborhood Hits	600	Target Neighborhood Hits	1026	Shared Neighborhood Hits	124
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

FGRL1_HUMAN
θ value	θ > 10 (rank : 763)	NC score	0.230589 (rank : 353)
Query Neighborhood Hits	600	Target Neighborhood Hits	335	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

FGRL1_MOUSE
θ value	θ > 10 (rank : 764)	NC score	0.229161 (rank : 356)
Query Neighborhood Hits	600	Target Neighborhood Hits	325	Shared Neighborhood Hits	87
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

FGR_HUMAN
θ value	θ > 10 (rank : 765)	NC score	0.051743 (rank : 1050)
Query Neighborhood Hits	600	Target Neighborhood Hits	1067	Shared Neighborhood Hits	58
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_MOUSE
θ value	θ > 10 (rank : 766)	NC score	0.051583 (rank : 1054)
Query Neighborhood Hits	600	Target Neighborhood Hits	1069	Shared Neighborhood Hits	58
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FLT3_HUMAN
θ value	θ > 10 (rank : 767)	NC score	0.063847 (rank : 923)
Query Neighborhood Hits	600	Target Neighborhood Hits	843	Shared Neighborhood Hits	72
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

FLT3_MOUSE
θ value	θ > 10 (rank : 768)	NC score	0.072526 (rank : 865)
Query Neighborhood Hits	600	Target Neighborhood Hits	847	Shared Neighborhood Hits	86
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

FRK_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.051540 (rank : 1055)
Query Neighborhood Hits	600	Target Neighborhood Hits	1058	Shared Neighborhood Hits	55
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FSTL3_HUMAN
θ value	θ > 10 (rank : 770)	NC score	0.108490 (rank : 668)
Query Neighborhood Hits	600	Target Neighborhood Hits	162	Shared Neighborhood Hits	84
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 771)	NC score	0.098171 (rank : 707)
Query Neighborhood Hits	600	Target Neighborhood Hits	152	Shared Neighborhood Hits	76
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL4_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.185963 (rank : 435)
Query Neighborhood Hits	600	Target Neighborhood Hits	344	Shared Neighborhood Hits	93
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL4_MOUSE
θ value	θ > 10 (rank : 773)	NC score	0.188472 (rank : 425)
Query Neighborhood Hits	600	Target Neighborhood Hits	333	Shared Neighborhood Hits	92
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL5_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.186708 (rank : 432)
Query Neighborhood Hits	600	Target Neighborhood Hits	347	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	θ > 10 (rank : 775)	NC score	0.184423 (rank : 440)
Query Neighborhood Hits	600	Target Neighborhood Hits	355	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FST_HUMAN
θ value	θ > 10 (rank : 776)	NC score	0.067158 (rank : 906)
Query Neighborhood Hits	600	Target Neighborhood Hits	129	Shared Neighborhood Hits	54
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 777)	NC score	0.070989 (rank : 876)
Query Neighborhood Hits	600	Target Neighborhood Hits	146	Shared Neighborhood Hits	68
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FYN_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.050338 (rank : 1065)
Query Neighborhood Hits	600	Target Neighborhood Hits	1073	Shared Neighborhood Hits	57
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GLPC_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.054123 (rank : 1010)
Query Neighborhood Hits	600	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

GP116_HUMAN
θ value	θ > 10 (rank : 780)	NC score	0.063536 (rank : 926)
Query Neighborhood Hits	600	Target Neighborhood Hits	167	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP128_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.055932 (rank : 991)
Query Neighborhood Hits	600	Target Neighborhood Hits	135	Shared Neighborhood Hits	37
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP128_MOUSE
θ value	θ > 10 (rank : 782)	NC score	0.059596 (rank : 964)
Query Neighborhood Hits	600	Target Neighborhood Hits	141	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GPA33_HUMAN
θ value	θ > 10 (rank : 783)	NC score	0.118669 (rank : 629)
Query Neighborhood Hits	600	Target Neighborhood Hits	273	Shared Neighborhood Hits	65
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

GPA33_MOUSE
θ value	θ > 10 (rank : 784)	NC score	0.122103 (rank : 616)
Query Neighborhood Hits	600	Target Neighborhood Hits	294	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

GRN_HUMAN
θ value	θ > 10 (rank : 785)	NC score	0.237496 (rank : 336)
Query Neighborhood Hits	600	Target Neighborhood Hits	268	Shared Neighborhood Hits	148
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 786)	NC score	0.242691 (rank : 332)
Query Neighborhood Hits	600	Target Neighborhood Hits	248	Shared Neighborhood Hits	144
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HCK_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.052562 (rank : 1034)
Query Neighborhood Hits	600	Target Neighborhood Hits	1035	Shared Neighborhood Hits	57
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 788)	NC score	0.052842 (rank : 1029)
Query Neighborhood Hits	600	Target Neighborhood Hits	1029	Shared Neighborhood Hits	55
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HGFA_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.128617 (rank : 593)
Query Neighborhood Hits	600	Target Neighborhood Hits	436	Shared Neighborhood Hits	167
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HHIP_HUMAN
θ value	θ > 10 (rank : 790)	NC score	0.343111 (rank : 200)
Query Neighborhood Hits	600	Target Neighborhood Hits	249	Shared Neighborhood Hits	175
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 791)	NC score	0.330199 (rank : 215)
Query Neighborhood Hits	600	Target Neighborhood Hits	219	Shared Neighborhood Hits	160
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHLA2_HUMAN
θ value	θ > 10 (rank : 792)	NC score	0.060514 (rank : 952)
Query Neighborhood Hits	600	Target Neighborhood Hits	140	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

HMCN1_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.339841 (rank : 203)
Query Neighborhood Hits	600	Target Neighborhood Hits	983	Shared Neighborhood Hits	299
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

I11RA_HUMAN
θ value	θ > 10 (rank : 794)	NC score	0.069572 (rank : 888)
Query Neighborhood Hits	600	Target Neighborhood Hits	138	Shared Neighborhood Hits	54
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

I11RA_MOUSE
θ value	θ > 10 (rank : 795)	NC score	0.067866 (rank : 901)
Query Neighborhood Hits	600	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

I11RB_MOUSE
θ value	θ > 10 (rank : 796)	NC score	0.075576 (rank : 851)
Query Neighborhood Hits	600	Target Neighborhood Hits	101	Shared Neighborhood Hits	51
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

I12R1_HUMAN
θ value	θ > 10 (rank : 797)	NC score	0.107013 (rank : 672)
Query Neighborhood Hits	600	Target Neighborhood Hits	78	Shared Neighborhood Hits	64
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

I12R1_MOUSE
θ value	θ > 10 (rank : 798)	NC score	0.099254 (rank : 701)
Query Neighborhood Hits	600	Target Neighborhood Hits	70	Shared Neighborhood Hits	54
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

I27RA_HUMAN
θ value	θ > 10 (rank : 799)	NC score	0.115265 (rank : 638)
Query Neighborhood Hits	600	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

I27RA_MOUSE
θ value	θ > 10 (rank : 800)	NC score	0.084994 (rank : 801)
Query Neighborhood Hits	600	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

IBP7_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.174430 (rank : 472)
Query Neighborhood Hits	600	Target Neighborhood Hits	220	Shared Neighborhood Hits	82
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
θ value	θ > 10 (rank : 802)	NC score	0.175655 (rank : 468)
Query Neighborhood Hits	600	Target Neighborhood Hits	230	Shared Neighborhood Hits	92
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ICAM5_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.186309 (rank : 433)
Query Neighborhood Hits	600	Target Neighborhood Hits	276	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

ICAM5_MOUSE
θ value	θ > 10 (rank : 804)	NC score	0.191192 (rank : 416)
Query Neighborhood Hits	600	Target Neighborhood Hits	308	Shared Neighborhood Hits	83
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

IGS21_HUMAN
θ value	θ > 10 (rank : 805)	NC score	0.094977 (rank : 725)
Query Neighborhood Hits	600	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS21_MOUSE
θ value	θ > 10 (rank : 806)	NC score	0.091307 (rank : 748)
Query Neighborhood Hits	600	Target Neighborhood Hits	118	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS4B_HUMAN
θ value	θ > 10 (rank : 807)	NC score	0.158520 (rank : 512)
Query Neighborhood Hits	600	Target Neighborhood Hits	305	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

IGS4B_MOUSE
θ value	θ > 10 (rank : 808)	NC score	0.159456 (rank : 509)
Query Neighborhood Hits	600	Target Neighborhood Hits	328	Shared Neighborhood Hits	81
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

IL1R1_HUMAN
θ value	θ > 10 (rank : 809)	NC score	0.070842 (rank : 879)
Query Neighborhood Hits	600	Target Neighborhood Hits	140	Shared Neighborhood Hits	54
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

IL1R1_MOUSE
θ value	θ > 10 (rank : 810)	NC score	0.072634 (rank : 863)
Query Neighborhood Hits	600	Target Neighborhood Hits	142	Shared Neighborhood Hits	58
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

IL1R2_HUMAN
θ value	θ > 10 (rank : 811)	NC score	0.117235 (rank : 632)
Query Neighborhood Hits	600	Target Neighborhood Hits	153	Shared Neighborhood Hits	61
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

IL1R2_MOUSE
θ value	θ > 10 (rank : 812)	NC score	0.102485 (rank : 685)
Query Neighborhood Hits	600	Target Neighborhood Hits	125	Shared Neighborhood Hits	51
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IL27B_MOUSE
θ value	θ > 10 (rank : 813)	NC score	0.053874 (rank : 1013)
Query Neighborhood Hits	600	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

IL6RA_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.054787 (rank : 1002)
Query Neighborhood Hits	600	Target Neighborhood Hits	96	Shared Neighborhood Hits	38
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

IL6RA_MOUSE
θ value	θ > 10 (rank : 815)	NC score	0.073314 (rank : 858)
Query Neighborhood Hits	600	Target Neighborhood Hits	104	Shared Neighborhood Hits	47
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

ILK1_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.058972 (rank : 976)
Query Neighborhood Hits	600	Target Neighborhood Hits	857	Shared Neighborhood Hits	63
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.059014 (rank : 974)
Query Neighborhood Hits	600	Target Neighborhood Hits	848	Shared Neighborhood Hits	63
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ILK_MOUSE
θ value	θ > 10 (rank : 818)	NC score	0.059013 (rank : 975)
Query Neighborhood Hits	600	Target Neighborhood Hits	858	Shared Neighborhood Hits	63
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ILRL1_HUMAN
θ value	θ > 10 (rank : 819)	NC score	0.069733 (rank : 884)
Query Neighborhood Hits	600	Target Neighborhood Hits	167	Shared Neighborhood Hits	53
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

ILRL2_MOUSE
θ value	θ > 10 (rank : 820)	NC score	0.076515 (rank : 846)
Query Neighborhood Hits	600	Target Neighborhood Hits	158	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

IRPL1_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.085701 (rank : 797)
Query Neighborhood Hits	600	Target Neighborhood Hits	196	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

IRPL1_MOUSE
θ value	θ > 10 (rank : 822)	NC score	0.091401 (rank : 745)
Query Neighborhood Hits	600	Target Neighborhood Hits	186	Shared Neighborhood Hits	67
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

IRPL2_HUMAN
θ value	θ > 10 (rank : 823)	NC score	0.095944 (rank : 718)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

IRPL2_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.095198 (rank : 724)
Query Neighborhood Hits	600	Target Neighborhood Hits	195	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

ITK_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.052501 (rank : 1035)
Query Neighborhood Hits	600	Target Neighborhood Hits	1016	Shared Neighborhood Hits	57
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITK_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.052651 (rank : 1031)
Query Neighborhood Hits	600	Target Neighborhood Hits	985	Shared Neighborhood Hits	57
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

JAM1_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.171460 (rank : 475)
Query Neighborhood Hits	600	Target Neighborhood Hits	294	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

JAM1_MOUSE
θ value	θ > 10 (rank : 828)	NC score	0.166468 (rank : 490)
Query Neighborhood Hits	600	Target Neighborhood Hits	287	Shared Neighborhood Hits	80
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

JAM2_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.150761 (rank : 532)
Query Neighborhood Hits	600	Target Neighborhood Hits	304	Shared Neighborhood Hits	83
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM2_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.144532 (rank : 549)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM3_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.177030 (rank : 459)
Query Neighborhood Hits	600	Target Neighborhood Hits	271	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAM3_MOUSE
θ value	θ > 10 (rank : 832)	NC score	0.175474 (rank : 470)
Query Neighborhood Hits	600	Target Neighborhood Hits	286	Shared Neighborhood Hits	79
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAML1_MOUSE
θ value	θ > 10 (rank : 833)	NC score	0.064839 (rank : 920)
Query Neighborhood Hits	600	Target Neighborhood Hits	185	Shared Neighborhood Hits	42
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

KAZD1_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.200347 (rank : 402)
Query Neighborhood Hits	600	Target Neighborhood Hits	248	Shared Neighborhood Hits	97
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 835)	NC score	0.197336 (rank : 410)
Query Neighborhood Hits	600	Target Neighborhood Hits	281	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KIRR1_HUMAN
θ value	θ > 10 (rank : 836)	NC score	0.171560 (rank : 474)
Query Neighborhood Hits	600	Target Neighborhood Hits	401	Shared Neighborhood Hits	81
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR1_MOUSE
θ value	θ > 10 (rank : 837)	NC score	0.169437 (rank : 479)
Query Neighborhood Hits	600	Target Neighborhood Hits	403	Shared Neighborhood Hits	81
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR2_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.190357 (rank : 420)
Query Neighborhood Hits	600	Target Neighborhood Hits	321	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

KIRR2_MOUSE
θ value	θ > 10 (rank : 839)	NC score	0.187387 (rank : 428)
Query Neighborhood Hits	600	Target Neighborhood Hits	326	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

KIRR3_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.170932 (rank : 477)
Query Neighborhood Hits	600	Target Neighborhood Hits	302	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

KIRR3_MOUSE
θ value	θ > 10 (rank : 841)	NC score	0.167635 (rank : 487)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

KIT_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.093059 (rank : 735)
Query Neighborhood Hits	600	Target Neighborhood Hits	953	Shared Neighborhood Hits	115
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 843)	NC score	0.099236 (rank : 702)
Query Neighborhood Hits	600	Target Neighborhood Hits	949	Shared Neighborhood Hits	115
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KR101_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.334494 (rank : 209)
Query Neighborhood Hits	600	Target Neighborhood Hits	261	Shared Neighborhood Hits	147
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 845)	NC score	0.291919 (rank : 260)
Query Neighborhood Hits	600	Target Neighborhood Hits	264	Shared Neighborhood Hits	145
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.208715 (rank : 388)
Query Neighborhood Hits	600	Target Neighborhood Hits	212	Shared Neighborhood Hits	117
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR105_HUMAN
θ value	θ > 10 (rank : 847)	NC score	0.276064 (rank : 283)
Query Neighborhood Hits	600	Target Neighborhood Hits	271	Shared Neighborhood Hits	148
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR109_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.276236 (rank : 282)
Query Neighborhood Hits	600	Target Neighborhood Hits	226	Shared Neighborhood Hits	130
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	θ > 10 (rank : 849)	NC score	0.272833 (rank : 290)
Query Neighborhood Hits	600	Target Neighborhood Hits	269	Shared Neighborhood Hits	140
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 850)	NC score	0.276528 (rank : 281)
Query Neighborhood Hits	600	Target Neighborhood Hits	219	Shared Neighborhood Hits	128
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR122_HUMAN
θ value	θ > 10 (rank : 851)	NC score	0.090753 (rank : 756)
Query Neighborhood Hits	600	Target Neighborhood Hits	97	Shared Neighborhood Hits	45
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR124_HUMAN
θ value	θ > 10 (rank : 852)	NC score	0.064261 (rank : 922)
Query Neighborhood Hits	600	Target Neighborhood Hits	124	Shared Neighborhood Hits	64
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR241_HUMAN
θ value	θ > 10 (rank : 853)	NC score	0.090871 (rank : 755)
Query Neighborhood Hits	600	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KR410_HUMAN
θ value	θ > 10 (rank : 854)	NC score	0.160014 (rank : 506)
Query Neighborhood Hits	600	Target Neighborhood Hits	156	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 855)	NC score	0.199763 (rank : 404)
Query Neighborhood Hits	600	Target Neighborhood Hits	178	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 856)	NC score	0.095968 (rank : 717)
Query Neighborhood Hits	600	Target Neighborhood Hits	112	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.233210 (rank : 345)
Query Neighborhood Hits	600	Target Neighborhood Hits	199	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA11_HUMAN
θ value	θ > 10 (rank : 858)	NC score	0.250929 (rank : 317)
Query Neighborhood Hits	600	Target Neighborhood Hits	155	Shared Neighborhood Hits	86
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 859)	NC score	0.225618 (rank : 361)
Query Neighborhood Hits	600	Target Neighborhood Hits	144	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 860)	NC score	0.189551 (rank : 422)
Query Neighborhood Hits	600	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 861)	NC score	0.125432 (rank : 600)
Query Neighborhood Hits	600	Target Neighborhood Hits	192	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA42_HUMAN
θ value	θ > 10 (rank : 862)	NC score	0.133732 (rank : 572)
Query Neighborhood Hits	600	Target Neighborhood Hits	149	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 863)	NC score	0.216698 (rank : 373)
Query Neighborhood Hits	600	Target Neighborhood Hits	162	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA47_HUMAN
θ value	θ > 10 (rank : 864)	NC score	0.261684 (rank : 303)
Query Neighborhood Hits	600	Target Neighborhood Hits	204	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA92_HUMAN
θ value	θ > 10 (rank : 865)	NC score	0.222580 (rank : 365)
Query Neighborhood Hits	600	Target Neighborhood Hits	198	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA94_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.233073 (rank : 347)
Query Neighborhood Hits	600	Target Neighborhood Hits	204	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 867)	NC score	0.221645 (rank : 366)
Query Neighborhood Hits	600	Target Neighborhood Hits	185	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 868)	NC score	0.181800 (rank : 449)
Query Neighborhood Hits	600	Target Neighborhood Hits	173	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

KSYK_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.056415 (rank : 989)
Query Neighborhood Hits	600	Target Neighborhood Hits	901	Shared Neighborhood Hits	54
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 870)	NC score	0.056461 (rank : 988)
Query Neighborhood Hits	600	Target Neighborhood Hits	944	Shared Neighborhood Hits	57
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAG3_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.062019 (rank : 938)
Query Neighborhood Hits	600	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

LAG3_MOUSE
θ value	θ > 10 (rank : 872)	NC score	0.062308 (rank : 935)
Query Neighborhood Hits	600	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

LCE1A_HUMAN
θ value	θ > 10 (rank : 873)	NC score	0.156390 (rank : 517)
Query Neighborhood Hits	600	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 874)	NC score	0.211040 (rank : 382)
Query Neighborhood Hits	600	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.232469 (rank : 350)
Query Neighborhood Hits	600	Target Neighborhood Hits	65	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.154629 (rank : 523)
Query Neighborhood Hits	600	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.148751 (rank : 538)
Query Neighborhood Hits	600	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 878)	NC score	0.155249 (rank : 520)
Query Neighborhood Hits	600	Target Neighborhood Hits	48	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 879)	NC score	0.130849 (rank : 585)
Query Neighborhood Hits	600	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.142975 (rank : 555)
Query Neighborhood Hits	600	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.134503 (rank : 571)
Query Neighborhood Hits	600	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 882)	NC score	0.153543 (rank : 527)
Query Neighborhood Hits	600	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 883)	NC score	0.154371 (rank : 525)
Query Neighborhood Hits	600	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 884)	NC score	0.063258 (rank : 927)
Query Neighborhood Hits	600	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE4A_HUMAN
θ value	θ > 10 (rank : 885)	NC score	0.099159 (rank : 703)
Query Neighborhood Hits	600	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCK_HUMAN
θ value	θ > 10 (rank : 886)	NC score	0.052785 (rank : 1030)
Query Neighborhood Hits	600	Target Neighborhood Hits	987	Shared Neighborhood Hits	57
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.052583 (rank : 1032)
Query Neighborhood Hits	600	Target Neighborhood Hits	981	Shared Neighborhood Hits	54
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LDLR_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.243563 (rank : 329)
Query Neighborhood Hits	600	Target Neighborhood Hits	375	Shared Neighborhood Hits	202
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRC21_HUMAN
θ value	θ > 10 (rank : 889)	NC score	0.114999 (rank : 639)
Query Neighborhood Hits	600	Target Neighborhood Hits	456	Shared Neighborhood Hits	103
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC21_MOUSE
θ value	θ > 10 (rank : 890)	NC score	0.117178 (rank : 634)
Query Neighborhood Hits	600	Target Neighborhood Hits	462	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC24_HUMAN
θ value	θ > 10 (rank : 891)	NC score	0.082651 (rank : 811)
Query Neighborhood Hits	600	Target Neighborhood Hits	404	Shared Neighborhood Hits	83
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC24_MOUSE
θ value	θ > 10 (rank : 892)	NC score	0.072649 (rank : 862)
Query Neighborhood Hits	600	Target Neighborhood Hits	387	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC4B_HUMAN
θ value	θ > 10 (rank : 893)	NC score	0.069719 (rank : 885)
Query Neighborhood Hits	600	Target Neighborhood Hits	479	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRC4B_MOUSE
θ value	θ > 10 (rank : 894)	NC score	0.070804 (rank : 880)
Query Neighborhood Hits	600	Target Neighborhood Hits	484	Shared Neighborhood Hits	81
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRFN2_HUMAN
θ value	θ > 10 (rank : 895)	NC score	0.108764 (rank : 666)
Query Neighborhood Hits	600	Target Neighborhood Hits	450	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN2_MOUSE
θ value	θ > 10 (rank : 896)	NC score	0.109652 (rank : 659)
Query Neighborhood Hits	600	Target Neighborhood Hits	450	Shared Neighborhood Hits	96
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN3_HUMAN
θ value	θ > 10 (rank : 897)	NC score	0.104729 (rank : 679)
Query Neighborhood Hits	600	Target Neighborhood Hits	444	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN3_MOUSE
θ value	θ > 10 (rank : 898)	NC score	0.109398 (rank : 662)
Query Neighborhood Hits	600	Target Neighborhood Hits	455	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN4_HUMAN
θ value	θ > 10 (rank : 899)	NC score	0.118677 (rank : 628)
Query Neighborhood Hits	600	Target Neighborhood Hits	462	Shared Neighborhood Hits	102
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN4_MOUSE
θ value	θ > 10 (rank : 900)	NC score	0.114688 (rank : 641)
Query Neighborhood Hits	600	Target Neighborhood Hits	442	Shared Neighborhood Hits	96
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN5_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.097597 (rank : 711)
Query Neighborhood Hits	600	Target Neighborhood Hits	464	Shared Neighborhood Hits	90
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRFN5_MOUSE
θ value	θ > 10 (rank : 902)	NC score	0.099931 (rank : 695)
Query Neighborhood Hits	600	Target Neighborhood Hits	472	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRIG1_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.168140 (rank : 485)
Query Neighborhood Hits	600	Target Neighborhood Hits	654	Shared Neighborhood Hits	100
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG1_MOUSE
θ value	θ > 10 (rank : 904)	NC score	0.166614 (rank : 489)
Query Neighborhood Hits	600	Target Neighborhood Hits	627	Shared Neighborhood Hits	100
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_HUMAN
θ value	θ > 10 (rank : 905)	NC score	0.168938 (rank : 482)
Query Neighborhood Hits	600	Target Neighborhood Hits	595	Shared Neighborhood Hits	101
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
θ value	θ > 10 (rank : 906)	NC score	0.169042 (rank : 481)
Query Neighborhood Hits	600	Target Neighborhood Hits	586	Shared Neighborhood Hits	101
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG3_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.162518 (rank : 502)
Query Neighborhood Hits	600	Target Neighborhood Hits	601	Shared Neighborhood Hits	103
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRIG3_MOUSE
θ value	θ > 10 (rank : 908)	NC score	0.163814 (rank : 500)
Query Neighborhood Hits	600	Target Neighborhood Hits	611	Shared Neighborhood Hits	102
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 909)	NC score	0.100939 (rank : 692)
Query Neighborhood Hits	600	Target Neighborhood Hits	280	Shared Neighborhood Hits	96
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP5_HUMAN
θ value	θ > 10 (rank : 910)	NC score	0.091324 (rank : 747)
Query Neighborhood Hits	600	Target Neighborhood Hits	224	Shared Neighborhood Hits	90
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 911)	NC score	0.096053 (rank : 716)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	99
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_MOUSE
θ value	θ > 10 (rank : 912)	NC score	0.095754 (rank : 720)
Query Neighborhood Hits	600	Target Neighborhood Hits	232	Shared Neighborhood Hits	94
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.217468 (rank : 371)
Query Neighborhood Hits	600	Target Neighborhood Hits	346	Shared Neighborhood Hits	176
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRRC4_HUMAN
θ value	θ > 10 (rank : 914)	NC score	0.065748 (rank : 917)
Query Neighborhood Hits	600	Target Neighborhood Hits	444	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

LRRC4_MOUSE
θ value	θ > 10 (rank : 915)	NC score	0.056408 (rank : 990)
Query Neighborhood Hits	600	Target Neighborhood Hits	412	Shared Neighborhood Hits	75
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

LRRN1_HUMAN
θ value	θ > 10 (rank : 916)	NC score	0.097859 (rank : 710)
Query Neighborhood Hits	600	Target Neighborhood Hits	518	Shared Neighborhood Hits	104
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN1_MOUSE
θ value	θ > 10 (rank : 917)	NC score	0.094031 (rank : 729)
Query Neighborhood Hits	600	Target Neighborhood Hits	508	Shared Neighborhood Hits	103
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN3_HUMAN
θ value	θ > 10 (rank : 918)	NC score	0.094537 (rank : 727)
Query Neighborhood Hits	600	Target Neighborhood Hits	461	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN3_MOUSE
θ value	θ > 10 (rank : 919)	NC score	0.088059 (rank : 781)
Query Neighborhood Hits	600	Target Neighborhood Hits	455	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN5_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.084058 (rank : 808)
Query Neighborhood Hits	600	Target Neighborhood Hits	493	Shared Neighborhood Hits	91
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

LSAMP_HUMAN
θ value	θ > 10 (rank : 921)	NC score	0.198547 (rank : 408)
Query Neighborhood Hits	600	Target Neighborhood Hits	347	Shared Neighborhood Hits	84
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
θ value	θ > 10 (rank : 922)	NC score	0.200473 (rank : 401)
Query Neighborhood Hits	600	Target Neighborhood Hits	344	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

LTK_HUMAN
θ value	θ > 10 (rank : 923)	NC score	0.069169 (rank : 891)
Query Neighborhood Hits	600	Target Neighborhood Hits	774	Shared Neighborhood Hits	58
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 924)	NC score	0.069258 (rank : 890)
Query Neighborhood Hits	600	Target Neighborhood Hits	770	Shared Neighborhood Hits	58
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LU_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.185860 (rank : 436)
Query Neighborhood Hits	600	Target Neighborhood Hits	283	Shared Neighborhood Hits	84
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

LYAM1_HUMAN
θ value	θ > 10 (rank : 926)	NC score	0.163175 (rank : 501)
Query Neighborhood Hits	600	Target Neighborhood Hits	315	Shared Neighborhood Hits	144
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 927)	NC score	0.162183 (rank : 503)
Query Neighborhood Hits	600	Target Neighborhood Hits	332	Shared Neighborhood Hits	152
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYN_HUMAN
θ value	θ > 10 (rank : 928)	NC score	0.051632 (rank : 1052)
Query Neighborhood Hits	600	Target Neighborhood Hits	1022	Shared Neighborhood Hits	54
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 929)	NC score	0.051745 (rank : 1049)
Query Neighborhood Hits	600	Target Neighborhood Hits	1023	Shared Neighborhood Hits	55
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

MAG_HUMAN
θ value	θ > 10 (rank : 930)	NC score	0.184255 (rank : 441)
Query Neighborhood Hits	600	Target Neighborhood Hits	278	Shared Neighborhood Hits	82
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
θ value	θ > 10 (rank : 931)	NC score	0.184120 (rank : 442)
Query Neighborhood Hits	600	Target Neighborhood Hits	271	Shared Neighborhood Hits	82
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MALT1_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.200767 (rank : 400)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

MAMC1_HUMAN
θ value	θ > 10 (rank : 933)	NC score	0.235635 (rank : 341)
Query Neighborhood Hits	600	Target Neighborhood Hits	357	Shared Neighborhood Hits	92
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 934)	NC score	0.236845 (rank : 337)
Query Neighborhood Hits	600	Target Neighborhood Hits	357	Shared Neighborhood Hits	92
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MATK_HUMAN
θ value	θ > 10 (rank : 935)	NC score	0.054023 (rank : 1012)
Query Neighborhood Hits	600	Target Neighborhood Hits	954	Shared Neighborhood Hits	54
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 936)	NC score	0.053658 (rank : 1017)
Query Neighborhood Hits	600	Target Neighborhood Hits	952	Shared Neighborhood Hits	54
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MATN1_HUMAN
θ value	θ > 10 (rank : 937)	NC score	0.078890 (rank : 835)
Query Neighborhood Hits	600	Target Neighborhood Hits	191	Shared Neighborhood Hits	80
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 938)	NC score	0.079428 (rank : 832)
Query Neighborhood Hits	600	Target Neighborhood Hits	186	Shared Neighborhood Hits	77
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN2_MOUSE
θ value	θ > 10 (rank : 939)	NC score	0.269323 (rank : 297)
Query Neighborhood Hits	600	Target Neighborhood Hits	356	Shared Neighborhood Hits	191
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 940)	NC score	0.208566 (rank : 390)
Query Neighborhood Hits	600	Target Neighborhood Hits	268	Shared Neighborhood Hits	146
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 941)	NC score	0.212785 (rank : 379)
Query Neighborhood Hits	600	Target Neighborhood Hits	287	Shared Neighborhood Hits	161
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MCSP_MOUSE
θ value	θ > 10 (rank : 942)	NC score	0.094725 (rank : 726)
Query Neighborhood Hits	600	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEP1A_HUMAN
θ value	θ > 10 (rank : 943)	NC score	0.069121 (rank : 892)
Query Neighborhood Hits	600	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 944)	NC score	0.075911 (rank : 849)
Query Neighborhood Hits	600	Target Neighborhood Hits	166	Shared Neighborhood Hits	94
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_MOUSE
θ value	θ > 10 (rank : 945)	NC score	0.054351 (rank : 1007)
Query Neighborhood Hits	600	Target Neighborhood Hits	127	Shared Neighborhood Hits	71
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MET_HUMAN
θ value	θ > 10 (rank : 946)	NC score	0.058946 (rank : 977)
Query Neighborhood Hits	600	Target Neighborhood Hits	831	Shared Neighborhood Hits	54
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 947)	NC score	0.059266 (rank : 971)
Query Neighborhood Hits	600	Target Neighborhood Hits	844	Shared Neighborhood Hits	58
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MFA3L_HUMAN
θ value	θ > 10 (rank : 948)	NC score	0.148974 (rank : 536)
Query Neighborhood Hits	600	Target Neighborhood Hits	230	Shared Neighborhood Hits	77
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

MFA3L_MOUSE
θ value	θ > 10 (rank : 949)	NC score	0.129978 (rank : 590)
Query Neighborhood Hits	600	Target Neighborhood Hits	214	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

MFAP4_HUMAN
θ value	θ > 10 (rank : 950)	NC score	0.051703 (rank : 1051)
Query Neighborhood Hits	600	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_MOUSE
θ value	θ > 10 (rank : 951)	NC score	0.051780 (rank : 1048)
Query Neighborhood Hits	600	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFGM_HUMAN
θ value	θ > 10 (rank : 952)	NC score	0.121560 (rank : 622)
Query Neighborhood Hits	600	Target Neighborhood Hits	150	Shared Neighborhood Hits	93
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 953)	NC score	0.253389 (rank : 312)
Query Neighborhood Hits	600	Target Neighborhood Hits	233	Shared Neighborhood Hits	150
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MMRN1_HUMAN
θ value	θ > 10 (rank : 954)	NC score	0.111226 (rank : 652)
Query Neighborhood Hits	600	Target Neighborhood Hits	636	Shared Neighborhood Hits	107
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MOX2R_MOUSE
θ value	θ > 10 (rank : 955)	NC score	0.090701 (rank : 757)
Query Neighborhood Hits	600	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

MT1F_HUMAN
θ value	θ > 10 (rank : 956)	NC score	0.080481 (rank : 826)
Query Neighborhood Hits	600	Target Neighborhood Hits	73	Shared Neighborhood Hits	52
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1G_HUMAN
θ value	θ > 10 (rank : 957)	NC score	0.095389 (rank : 721)
Query Neighborhood Hits	600	Target Neighborhood Hits	63	Shared Neighborhood Hits	42
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT1L_HUMAN
θ value	θ > 10 (rank : 958)	NC score	0.095850 (rank : 719)
Query Neighborhood Hits	600	Target Neighborhood Hits	73	Shared Neighborhood Hits	49
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1M_HUMAN
θ value	θ > 10 (rank : 959)	NC score	0.061928 (rank : 939)
Query Neighborhood Hits	600	Target Neighborhood Hits	72	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

MT1_MOUSE
θ value	θ > 10 (rank : 960)	NC score	0.122978 (rank : 613)
Query Neighborhood Hits	600	Target Neighborhood Hits	72	Shared Neighborhood Hits	44
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT3_HUMAN
θ value	θ > 10 (rank : 961)	NC score	0.197017 (rank : 411)
Query Neighborhood Hits	600	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT4_HUMAN
θ value	θ > 10 (rank : 962)	NC score	0.123467 (rank : 611)
Query Neighborhood Hits	600	Target Neighborhood Hits	83	Shared Neighborhood Hits	55
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 963)	NC score	0.150441 (rank : 534)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_HUMAN
θ value	θ > 10 (rank : 964)	NC score	0.122742 (rank : 614)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC13_MOUSE
θ value	θ > 10 (rank : 965)	NC score	0.156190 (rank : 518)
Query Neighborhood Hits	600	Target Neighborhood Hits	447	Shared Neighborhood Hits	146
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC18_MOUSE
θ value	θ > 10 (rank : 966)	NC score	0.176899 (rank : 460)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

MUSK_HUMAN
θ value	θ > 10 (rank : 967)	NC score	0.165251 (rank : 496)
Query Neighborhood Hits	600	Target Neighborhood Hits	1074	Shared Neighborhood Hits	125
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 968)	NC score	0.165471 (rank : 495)
Query Neighborhood Hits	600	Target Neighborhood Hits	1057	Shared Neighborhood Hits	125
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MYBPH_MOUSE
θ value	θ > 10 (rank : 969)	NC score	0.210345 (rank : 383)
Query Neighborhood Hits	600	Target Neighborhood Hits	290	Shared Neighborhood Hits	117
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MYOTI_HUMAN
θ value	θ > 10 (rank : 970)	NC score	0.227500 (rank : 358)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

MYOTI_MOUSE
θ value	θ > 10 (rank : 971)	NC score	0.229127 (rank : 357)
Query Neighborhood Hits	600	Target Neighborhood Hits	297	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYPN_HUMAN
θ value	θ > 10 (rank : 972)	NC score	0.229749 (rank : 354)
Query Neighborhood Hits	600	Target Neighborhood Hits	418	Shared Neighborhood Hits	92
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

MYPN_MOUSE
θ value	θ > 10 (rank : 973)	NC score	0.225679 (rank : 360)
Query Neighborhood Hits	600	Target Neighborhood Hits	421	Shared Neighborhood Hits	93
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

NEGR1_HUMAN
θ value	θ > 10 (rank : 974)	NC score	0.200168 (rank : 403)
Query Neighborhood Hits	600	Target Neighborhood Hits	346	Shared Neighborhood Hits	83
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

NEGR1_MOUSE
θ value	θ > 10 (rank : 975)	NC score	0.198822 (rank : 407)
Query Neighborhood Hits	600	Target Neighborhood Hits	349	Shared Neighborhood Hits	83
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

NELL2_HUMAN
θ value	θ > 10 (rank : 976)	NC score	0.364825 (rank : 167)
Query Neighborhood Hits	600	Target Neighborhood Hits	449	Shared Neighborhood Hits	242
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NGL1_HUMAN
θ value	θ > 10 (rank : 977)	NC score	0.067964 (rank : 899)
Query Neighborhood Hits	600	Target Neighborhood Hits	511	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_MOUSE
θ value	θ > 10 (rank : 978)	NC score	0.068057 (rank : 898)
Query Neighborhood Hits	600	Target Neighborhood Hits	512	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NID2_MOUSE
θ value	θ > 10 (rank : 979)	NC score	0.283754 (rank : 269)
Query Neighborhood Hits	600	Target Neighborhood Hits	338	Shared Neighborhood Hits	198
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NPTN_HUMAN
θ value	θ > 10 (rank : 980)	NC score	0.185986 (rank : 434)
Query Neighborhood Hits	600	Target Neighborhood Hits	212	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NPTN_MOUSE
θ value	θ > 10 (rank : 981)	NC score	0.175769 (rank : 467)
Query Neighborhood Hits	600	Target Neighborhood Hits	216	Shared Neighborhood Hits	75
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NRG1_HUMAN
θ value	θ > 10 (rank : 982)	NC score	0.182206 (rank : 448)
Query Neighborhood Hits	600	Target Neighborhood Hits	285	Shared Neighborhood Hits	133
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 983)	NC score	0.205901 (rank : 393)
Query Neighborhood Hits	600	Target Neighborhood Hits	419	Shared Neighborhood Hits	149
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 984)	NC score	0.222959 (rank : 364)
Query Neighborhood Hits	600	Target Neighborhood Hits	392	Shared Neighborhood Hits	162
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG4_HUMAN
θ value	θ > 10 (rank : 985)	NC score	0.073055 (rank : 859)
Query Neighborhood Hits	600	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 986)	NC score	0.070844 (rank : 878)
Query Neighborhood Hits	600	Target Neighborhood Hits	79	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRX1B_HUMAN
θ value	θ > 10 (rank : 987)	NC score	0.140118 (rank : 560)
Query Neighborhood Hits	600	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

NRX2B_HUMAN
θ value	θ > 10 (rank : 988)	NC score	0.101731 (rank : 690)
Query Neighborhood Hits	600	Target Neighborhood Hits	481	Shared Neighborhood Hits	42
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

NRX3B_HUMAN
θ value	θ > 10 (rank : 989)	NC score	0.143740 (rank : 552)
Query Neighborhood Hits	600	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

NTRI_HUMAN
θ value	θ > 10 (rank : 990)	NC score	0.189229 (rank : 423)
Query Neighborhood Hits	600	Target Neighborhood Hits	344	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

NTRI_MOUSE
θ value	θ > 10 (rank : 991)	NC score	0.190985 (rank : 418)
Query Neighborhood Hits	600	Target Neighborhood Hits	342	Shared Neighborhood Hits	85
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

NTRK1_HUMAN
θ value	θ > 10 (rank : 992)	NC score	0.081944 (rank : 818)
Query Neighborhood Hits	600	Target Neighborhood Hits	1023	Shared Neighborhood Hits	115
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 993)	NC score	0.109132 (rank : 664)
Query Neighborhood Hits	600	Target Neighborhood Hits	1081	Shared Neighborhood Hits	130
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 994)	NC score	0.108431 (rank : 669)
Query Neighborhood Hits	600	Target Neighborhood Hits	1088	Shared Neighborhood Hits	130
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 995)	NC score	0.108525 (rank : 667)
Query Neighborhood Hits	600	Target Neighborhood Hits	1115	Shared Neighborhood Hits	132
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

OBSL1_HUMAN
θ value	θ > 10 (rank : 996)	NC score	0.249464 (rank : 319)
Query Neighborhood Hits	600	Target Neighborhood Hits	354	Shared Neighborhood Hits	87
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

ODFP_MOUSE
θ value	θ > 10 (rank : 997)	NC score	0.092578 (rank : 738)
Query Neighborhood Hits	600	Target Neighborhood Hits	75	Shared Neighborhood Hits	45
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

OPCM_HUMAN
θ value	θ > 10 (rank : 998)	NC score	0.198228 (rank : 409)
Query Neighborhood Hits	600	Target Neighborhood Hits	332	Shared Neighborhood Hits	86
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

OX2G_MOUSE
θ value	θ > 10 (rank : 999)	NC score	0.051846 (rank : 1046)
Query Neighborhood Hits	600	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	O54901, O54816, Q9JHD5	Gene names	Cd200, Mox2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen).

PAPPA_MOUSE
θ value	θ > 10 (rank : 1000)	NC score	0.063155 (rank : 929)
Query Neighborhood Hits	600	Target Neighborhood Hits	153	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PDL1_HUMAN
θ value	θ > 10 (rank : 1001)	NC score	0.082763 (rank : 810)
Query Neighborhood Hits	600	Target Neighborhood Hits	195	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL1_MOUSE
θ value	θ > 10 (rank : 1002)	NC score	0.065158 (rank : 918)
Query Neighborhood Hits	600	Target Neighborhood Hits	168	Shared Neighborhood Hits	54
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_MOUSE
θ value	θ > 10 (rank : 1003)	NC score	0.075903 (rank : 850)
Query Neighborhood Hits	600	Target Neighborhood Hits	116	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PECA1_HUMAN
θ value	θ > 10 (rank : 1004)	NC score	0.085099 (rank : 800)
Query Neighborhood Hits	600	Target Neighborhood Hits	178	Shared Neighborhood Hits	57
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

PECA1_MOUSE
θ value	θ > 10 (rank : 1005)	NC score	0.073617 (rank : 855)
Query Neighborhood Hits	600	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

PERT_HUMAN
θ value	θ > 10 (rank : 1006)	NC score	0.088879 (rank : 773)
Query Neighborhood Hits	600	Target Neighborhood Hits	221	Shared Neighborhood Hits	100
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 1007)	NC score	0.078837 (rank : 837)
Query Neighborhood Hits	600	Target Neighborhood Hits	221	Shared Neighborhood Hits	96
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGCA_HUMAN
θ value	θ > 10 (rank : 1008)	NC score	0.099544 (rank : 699)
Query Neighborhood Hits	600	Target Neighborhood Hits	821	Shared Neighborhood Hits	161
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCB_HUMAN
θ value	θ > 10 (rank : 1009)	NC score	0.122306 (rank : 615)
Query Neighborhood Hits	600	Target Neighborhood Hits	478	Shared Neighborhood Hits	153
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 1010)	NC score	0.133395 (rank : 573)
Query Neighborhood Hits	600	Target Neighborhood Hits	459	Shared Neighborhood Hits	157
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PGFRA_HUMAN
θ value	θ > 10 (rank : 1011)	NC score	0.101891 (rank : 689)
Query Neighborhood Hits	600	Target Neighborhood Hits	980	Shared Neighborhood Hits	117
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
θ value	θ > 10 (rank : 1012)	NC score	0.102438 (rank : 686)
Query Neighborhood Hits	600	Target Neighborhood Hits	975	Shared Neighborhood Hits	119
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRB_HUMAN
θ value	θ > 10 (rank : 1013)	NC score	0.092178 (rank : 739)
Query Neighborhood Hits	600	Target Neighborhood Hits	962	Shared Neighborhood Hits	119
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRB_MOUSE
θ value	θ > 10 (rank : 1014)	NC score	0.097866 (rank : 709)
Query Neighborhood Hits	600	Target Neighborhood Hits	960	Shared Neighborhood Hits	113
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRL_HUMAN
θ value	θ > 10 (rank : 1015)	NC score	0.078867 (rank : 836)
Query Neighborhood Hits	600	Target Neighborhood Hits	115	Shared Neighborhood Hits	52
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

PGFRL_MOUSE
θ value	θ > 10 (rank : 1016)	NC score	0.059911 (rank : 959)
Query Neighborhood Hits	600	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

PGH1_HUMAN
θ value	θ > 10 (rank : 1017)	NC score	0.081156 (rank : 822)
Query Neighborhood Hits	600	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_MOUSE
θ value	θ > 10 (rank : 1018)	NC score	0.091379 (rank : 746)
Query Neighborhood Hits	600	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 1019)	NC score	0.096352 (rank : 714)
Query Neighborhood Hits	600	Target Neighborhood Hits	103	Shared Neighborhood Hits	72
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 1020)	NC score	0.108307 (rank : 670)
Query Neighborhood Hits	600	Target Neighborhood Hits	113	Shared Neighborhood Hits	81
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PHXR5_MOUSE
θ value	θ > 10 (rank : 1021)	NC score	0.051263 (rank : 1057)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PIGR_HUMAN
θ value	θ > 10 (rank : 1022)	NC score	0.081813 (rank : 821)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	52
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

PIGR_MOUSE
θ value	θ > 10 (rank : 1023)	NC score	0.078225 (rank : 838)
Query Neighborhood Hits	600	Target Neighborhood Hits	214	Shared Neighborhood Hits	54
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

PRLR_HUMAN
θ value	θ > 10 (rank : 1024)	NC score	0.060145 (rank : 955)
Query Neighborhood Hits	600	Target Neighborhood Hits	95	Shared Neighborhood Hits	43
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

PRLR_MOUSE
θ value	θ > 10 (rank : 1025)	NC score	0.059752 (rank : 961)
Query Neighborhood Hits	600	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

PROC_HUMAN
θ value	θ > 10 (rank : 1026)	NC score	0.086578 (rank : 794)
Query Neighborhood Hits	600	Target Neighborhood Hits	406	Shared Neighborhood Hits	157
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 1027)	NC score	0.102611 (rank : 683)
Query Neighborhood Hits	600	Target Neighborhood Hits	426	Shared Neighborhood Hits	163
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROZ_HUMAN
θ value	θ > 10 (rank : 1028)	NC score	0.201210 (rank : 398)
Query Neighborhood Hits	600	Target Neighborhood Hits	422	Shared Neighborhood Hits	175
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 1029)	NC score	0.208742 (rank : 387)
Query Neighborhood Hits	600	Target Neighborhood Hits	410	Shared Neighborhood Hits	166
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PSG10_HUMAN
θ value	θ > 10 (rank : 1030)	NC score	0.091989 (rank : 740)
Query Neighborhood Hits	600	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

PSG11_HUMAN
θ value	θ > 10 (rank : 1031)	NC score	0.095302 (rank : 723)
Query Neighborhood Hits	600	Target Neighborhood Hits	223	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

PSG1_HUMAN
θ value	θ > 10 (rank : 1032)	NC score	0.093629 (rank : 731)
Query Neighborhood Hits	600	Target Neighborhood Hits	232	Shared Neighborhood Hits	73
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

PSG2_HUMAN
θ value	θ > 10 (rank : 1033)	NC score	0.090384 (rank : 759)
Query Neighborhood Hits	600	Target Neighborhood Hits	229	Shared Neighborhood Hits	70
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

PSG3_HUMAN
θ value	θ > 10 (rank : 1034)	NC score	0.103189 (rank : 682)
Query Neighborhood Hits	600	Target Neighborhood Hits	242	Shared Neighborhood Hits	75
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

PSG4_HUMAN
θ value	θ > 10 (rank : 1035)	NC score	0.100831 (rank : 693)
Query Neighborhood Hits	600	Target Neighborhood Hits	243	Shared Neighborhood Hits	70
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

PSG5_HUMAN
θ value	θ > 10 (rank : 1036)	NC score	0.081102 (rank : 823)
Query Neighborhood Hits	600	Target Neighborhood Hits	231	Shared Neighborhood Hits	71
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

PSG6_HUMAN
θ value	θ > 10 (rank : 1037)	NC score	0.093357 (rank : 733)
Query Neighborhood Hits	600	Target Neighborhood Hits	231	Shared Neighborhood Hits	69
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

PSG7_HUMAN
θ value	θ > 10 (rank : 1038)	NC score	0.095375 (rank : 722)
Query Neighborhood Hits	600	Target Neighborhood Hits	239	Shared Neighborhood Hits	71
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

PSG8_HUMAN
θ value	θ > 10 (rank : 1039)	NC score	0.098017 (rank : 708)
Query Neighborhood Hits	600	Target Neighborhood Hits	239	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

PSG9_HUMAN
θ value	θ > 10 (rank : 1040)	NC score	0.085770 (rank : 796)
Query Neighborhood Hits	600	Target Neighborhood Hits	221	Shared Neighborhood Hits	68
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

PTK6_MOUSE
θ value	θ > 10 (rank : 1041)	NC score	0.050287 (rank : 1066)
Query Neighborhood Hits	600	Target Neighborhood Hits	1026	Shared Neighborhood Hits	54
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

PTK7_HUMAN
θ value	θ > 10 (rank : 1042)	NC score	0.178864 (rank : 454)
Query Neighborhood Hits	600	Target Neighborhood Hits	1103	Shared Neighborhood Hits	126
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

PTN11_HUMAN
θ value	θ > 10 (rank : 1043)	NC score	0.079557 (rank : 830)
Query Neighborhood Hits	600	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 1044)	NC score	0.079538 (rank : 831)
Query Neighborhood Hits	600	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 1045)	NC score	0.088493 (rank : 778)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 1046)	NC score	0.087200 (rank : 791)
Query Neighborhood Hits	600	Target Neighborhood Hits	123	Shared Neighborhood Hits	23
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN13_HUMAN
θ value	θ > 10 (rank : 1047)	NC score	0.061860 (rank : 940)
Query Neighborhood Hits	600	Target Neighborhood Hits	471	Shared Neighborhood Hits	30
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	θ > 10 (rank : 1048)	NC score	0.062665 (rank : 932)
Query Neighborhood Hits	600	Target Neighborhood Hits	426	Shared Neighborhood Hits	28
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN14_HUMAN
θ value	θ > 10 (rank : 1049)	NC score	0.070916 (rank : 877)
Query Neighborhood Hits	600	Target Neighborhood Hits	163	Shared Neighborhood Hits	28
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	θ > 10 (rank : 1050)	NC score	0.070089 (rank : 881)
Query Neighborhood Hits	600	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN18_HUMAN
θ value	θ > 10 (rank : 1051)	NC score	0.087203 (rank : 790)
Query Neighborhood Hits	600	Target Neighborhood Hits	73	Shared Neighborhood Hits	21
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 1052)	NC score	0.091499 (rank : 744)
Query Neighborhood Hits	600	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 1053)	NC score	0.088893 (rank : 772)
Query Neighborhood Hits	600	Target Neighborhood Hits	84	Shared Neighborhood Hits	21
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 1054)	NC score	0.088815 (rank : 775)
Query Neighborhood Hits	600	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN21_HUMAN
θ value	θ > 10 (rank : 1055)	NC score	0.069329 (rank : 889)
Query Neighborhood Hits	600	Target Neighborhood Hits	143	Shared Neighborhood Hits	26
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
θ value	θ > 10 (rank : 1056)	NC score	0.069591 (rank : 887)
Query Neighborhood Hits	600	Target Neighborhood Hits	155	Shared Neighborhood Hits	28
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN22_HUMAN
θ value	θ > 10 (rank : 1057)	NC score	0.088940 (rank : 771)
Query Neighborhood Hits	600	Target Neighborhood Hits	109	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 1058)	NC score	0.086329 (rank : 795)
Query Neighborhood Hits	600	Target Neighborhood Hits	179	Shared Neighborhood Hits	25
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 1059)	NC score	0.077971 (rank : 840)
Query Neighborhood Hits	600	Target Neighborhood Hits	646	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 1060)	NC score	0.079669 (rank : 829)
Query Neighborhood Hits	600	Target Neighborhood Hits	726	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 1061)	NC score	0.089973 (rank : 762)
Query Neighborhood Hits	600	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 1062)	NC score	0.089373 (rank : 768)
Query Neighborhood Hits	600	Target Neighborhood Hits	107	Shared Neighborhood Hits	21
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN4_HUMAN
θ value	θ > 10 (rank : 1063)	NC score	0.067439 (rank : 904)
Query Neighborhood Hits	600	Target Neighborhood Hits	303	Shared Neighborhood Hits	28
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN5_HUMAN
θ value	θ > 10 (rank : 1064)	NC score	0.090977 (rank : 752)
Query Neighborhood Hits	600	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 1065)	NC score	0.091023 (rank : 751)
Query Neighborhood Hits	600	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 1066)	NC score	0.082433 (rank : 813)
Query Neighborhood Hits	600	Target Neighborhood Hits	234	Shared Neighborhood Hits	22
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 1067)	NC score	0.082161 (rank : 816)
Query Neighborhood Hits	600	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 1068)	NC score	0.091763 (rank : 741)
Query Neighborhood Hits	600	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 1069)	NC score	0.091757 (rank : 742)
Query Neighborhood Hits	600	Target Neighborhood Hits	71	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 1070)	NC score	0.090901 (rank : 753)
Query Neighborhood Hits	600	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 1071)	NC score	0.091198 (rank : 750)
Query Neighborhood Hits	600	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 1072)	NC score	0.088614 (rank : 776)
Query Neighborhood Hits	600	Target Neighborhood Hits	103	Shared Neighborhood Hits	23
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 1073)	NC score	0.088823 (rank : 774)
Query Neighborhood Hits	600	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 1074)	NC score	0.111084 (rank : 654)
Query Neighborhood Hits	600	Target Neighborhood Hits	101	Shared Neighborhood Hits	25
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 1075)	NC score	0.110800 (rank : 655)
Query Neighborhood Hits	600	Target Neighborhood Hits	93	Shared Neighborhood Hits	22
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_HUMAN
θ value	θ > 10 (rank : 1076)	NC score	0.111149 (rank : 653)
Query Neighborhood Hits	600	Target Neighborhood Hits	92	Shared Neighborhood Hits	21
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 1077)	NC score	0.111377 (rank : 650)
Query Neighborhood Hits	600	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRG_HUMAN
θ value	θ > 10 (rank : 1078)	NC score	0.110213 (rank : 657)
Query Neighborhood Hits	600	Target Neighborhood Hits	231	Shared Neighborhood Hits	63
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 1079)	NC score	0.109468 (rank : 661)
Query Neighborhood Hits	600	Target Neighborhood Hits	260	Shared Neighborhood Hits	63
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRN_HUMAN
θ value	θ > 10 (rank : 1080)	NC score	0.088380 (rank : 779)
Query Neighborhood Hits	600	Target Neighborhood Hits	156	Shared Neighborhood Hits	27
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 1081)	NC score	0.087477 (rank : 786)
Query Neighborhood Hits	600	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 1082)	NC score	0.089899 (rank : 763)
Query Neighborhood Hits	600	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PVRL1_HUMAN
θ value	θ > 10 (rank : 1083)	NC score	0.067568 (rank : 902)
Query Neighborhood Hits	600	Target Neighborhood Hits	219	Shared Neighborhood Hits	47
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

PVRL1_MOUSE
θ value	θ > 10 (rank : 1084)	NC score	0.062434 (rank : 933)
Query Neighborhood Hits	600	Target Neighborhood Hits	201	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

PVRL2_MOUSE
θ value	θ > 10 (rank : 1085)	NC score	0.050882 (rank : 1061)
Query Neighborhood Hits	600	Target Neighborhood Hits	242	Shared Neighborhood Hits	39
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

PVRL3_HUMAN
θ value	θ > 10 (rank : 1086)	NC score	0.067140 (rank : 907)
Query Neighborhood Hits	600	Target Neighborhood Hits	204	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

PVRL3_MOUSE
θ value	θ > 10 (rank : 1087)	NC score	0.072860 (rank : 860)
Query Neighborhood Hits	600	Target Neighborhood Hits	212	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

PVR_HUMAN
θ value	θ > 10 (rank : 1088)	NC score	0.061040 (rank : 948)
Query Neighborhood Hits	600	Target Neighborhood Hits	195	Shared Neighborhood Hits	47
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

RAGE_HUMAN
θ value	θ > 10 (rank : 1089)	NC score	0.184019 (rank : 444)
Query Neighborhood Hits	600	Target Neighborhood Hits	269	Shared Neighborhood Hits	83
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RAGE_MOUSE
θ value	θ > 10 (rank : 1090)	NC score	0.177870 (rank : 457)
Query Neighborhood Hits	600	Target Neighborhood Hits	295	Shared Neighborhood Hits	82
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RECK_HUMAN
θ value	θ > 10 (rank : 1091)	NC score	0.111950 (rank : 647)
Query Neighborhood Hits	600	Target Neighborhood Hits	189	Shared Neighborhood Hits	93
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 1092)	NC score	0.093587 (rank : 732)
Query Neighborhood Hits	600	Target Neighborhood Hits	158	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RELN_HUMAN
θ value	θ > 10 (rank : 1093)	NC score	0.130105 (rank : 589)
Query Neighborhood Hits	600	Target Neighborhood Hits	233	Shared Neighborhood Hits	136
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 1094)	NC score	0.135224 (rank : 570)
Query Neighborhood Hits	600	Target Neighborhood Hits	235	Shared Neighborhood Hits	139
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RET_HUMAN
θ value	θ > 10 (rank : 1095)	NC score	0.062383 (rank : 934)
Query Neighborhood Hits	600	Target Neighborhood Hits	873	Shared Neighborhood Hits	65
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 1096)	NC score	0.062884 (rank : 930)
Query Neighborhood Hits	600	Target Neighborhood Hits	884	Shared Neighborhood Hits	73
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RON_HUMAN
θ value	θ > 10 (rank : 1097)	NC score	0.057417 (rank : 986)
Query Neighborhood Hits	600	Target Neighborhood Hits	842	Shared Neighborhood Hits	59
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 1098)	NC score	0.058842 (rank : 978)
Query Neighborhood Hits	600	Target Neighborhood Hits	836	Shared Neighborhood Hits	59
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 1099)	NC score	0.110326 (rank : 656)
Query Neighborhood Hits	600	Target Neighborhood Hits	1018	Shared Neighborhood Hits	131
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 1100)	NC score	0.108769 (rank : 665)
Query Neighborhood Hits	600	Target Neighborhood Hits	1025	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 1101)	NC score	0.112904 (rank : 645)
Query Neighborhood Hits	600	Target Neighborhood Hits	1014	Shared Neighborhood Hits	129
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 1102)	NC score	0.116666 (rank : 635)
Query Neighborhood Hits	600	Target Neighborhood Hits	1000	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

RSPO2_HUMAN
θ value	θ > 10 (rank : 1103)	NC score	0.068974 (rank : 893)
Query Neighborhood Hits	600	Target Neighborhood Hits	90	Shared Neighborhood Hits	44
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	θ > 10 (rank : 1104)	NC score	0.066894 (rank : 909)
Query Neighborhood Hits	600	Target Neighborhood Hits	88	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO3_HUMAN
θ value	θ > 10 (rank : 1105)	NC score	0.077565 (rank : 843)
Query Neighborhood Hits	600	Target Neighborhood Hits	128	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 1106)	NC score	0.071090 (rank : 874)
Query Neighborhood Hits	600	Target Neighborhood Hits	120	Shared Neighborhood Hits	58
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 1107)	NC score	0.089063 (rank : 770)
Query Neighborhood Hits	600	Target Neighborhood Hits	110	Shared Neighborhood Hits	63
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 1108)	NC score	0.083476 (rank : 809)
Query Neighborhood Hits	600	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RYK_HUMAN
θ value	θ > 10 (rank : 1109)	NC score	0.072543 (rank : 864)
Query Neighborhood Hits	600	Target Neighborhood Hits	701	Shared Neighborhood Hits	53
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 1110)	NC score	0.071330 (rank : 872)
Query Neighborhood Hits	600	Target Neighborhood Hits	715	Shared Neighborhood Hits	53
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SIG10_HUMAN
θ value	θ > 10 (rank : 1111)	NC score	0.143749 (rank : 551)
Query Neighborhood Hits	600	Target Neighborhood Hits	363	Shared Neighborhood Hits	84
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

SIG11_HUMAN
θ value	θ > 10 (rank : 1112)	NC score	0.144080 (rank : 550)
Query Neighborhood Hits	600	Target Neighborhood Hits	273	Shared Neighborhood Hits	81
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

SIG12_HUMAN
θ value	θ > 10 (rank : 1113)	NC score	0.078964 (rank : 834)
Query Neighborhood Hits	600	Target Neighborhood Hits	245	Shared Neighborhood Hits	76
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

SIGL5_HUMAN
θ value	θ > 10 (rank : 1114)	NC score	0.087232 (rank : 789)
Query Neighborhood Hits	600	Target Neighborhood Hits	246	Shared Neighborhood Hits	69
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

SIGL5_MOUSE
θ value	θ > 10 (rank : 1115)	NC score	0.114789 (rank : 640)
Query Neighborhood Hits	600	Target Neighborhood Hits	271	Shared Neighborhood Hits	72
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

SIGL6_HUMAN
θ value	θ > 10 (rank : 1116)	NC score	0.072361 (rank : 867)
Query Neighborhood Hits	600	Target Neighborhood Hits	233	Shared Neighborhood Hits	72
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

SIGL8_HUMAN
θ value	θ > 10 (rank : 1117)	NC score	0.087453 (rank : 787)
Query Neighborhood Hits	600	Target Neighborhood Hits	252	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

SMDF_HUMAN
θ value	θ > 10 (rank : 1118)	NC score	0.087654 (rank : 785)
Query Neighborhood Hits	600	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SN_HUMAN
θ value	θ > 10 (rank : 1119)	NC score	0.183055 (rank : 446)
Query Neighborhood Hits	600	Target Neighborhood Hits	434	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

SPR2D_MOUSE
θ value	θ > 10 (rank : 1120)	NC score	0.061070 (rank : 946)
Query Neighborhood Hits	600	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2G_MOUSE
θ value	θ > 10 (rank : 1121)	NC score	0.053117 (rank : 1025)
Query Neighborhood Hits	600	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 1122)	NC score	0.057795 (rank : 982)
Query Neighborhood Hits	600	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SRC_HUMAN
θ value	θ > 10 (rank : 1123)	NC score	0.051162 (rank : 1060)
Query Neighborhood Hits	600	Target Neighborhood Hits	1058	Shared Neighborhood Hits	58
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SRC_MOUSE
θ value	θ > 10 (rank : 1124)	NC score	0.051629 (rank : 1053)
Query Neighborhood Hits	600	Target Neighborhood Hits	1033	Shared Neighborhood Hits	57
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SRMS_HUMAN
θ value	θ > 10 (rank : 1125)	NC score	0.054554 (rank : 1003)
Query Neighborhood Hits	600	Target Neighborhood Hits	946	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 1126)	NC score	0.053642 (rank : 1018)
Query Neighborhood Hits	600	Target Neighborhood Hits	964	Shared Neighborhood Hits	54
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

ST14_HUMAN
θ value	θ > 10 (rank : 1127)	NC score	0.057596 (rank : 985)
Query Neighborhood Hits	600	Target Neighborhood Hits	409	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 1128)	NC score	0.054871 (rank : 1001)
Query Neighborhood Hits	600	Target Neighborhood Hits	419	Shared Neighborhood Hits	128
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

STYK1_HUMAN
θ value	θ > 10 (rank : 1129)	NC score	0.059379 (rank : 968)
Query Neighborhood Hits	600	Target Neighborhood Hits	786	Shared Neighborhood Hits	57
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

STYK1_MOUSE
θ value	θ > 10 (rank : 1130)	NC score	0.061636 (rank : 942)
Query Neighborhood Hits	600	Target Neighborhood Hits	779	Shared Neighborhood Hits	55
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

SUSD1_HUMAN
θ value	θ > 10 (rank : 1131)	NC score	0.258275 (rank : 310)
Query Neighborhood Hits	600	Target Neighborhood Hits	285	Shared Neighborhood Hits	166
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 1132)	NC score	0.148943 (rank : 537)
Query Neighborhood Hits	600	Target Neighborhood Hits	132	Shared Neighborhood Hits	93
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 1133)	NC score	0.189050 (rank : 424)
Query Neighborhood Hits	600	Target Neighborhood Hits	146	Shared Neighborhood Hits	107
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 1134)	NC score	0.145738 (rank : 546)
Query Neighborhood Hits	600	Target Neighborhood Hits	131	Shared Neighborhood Hits	92
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TECTA_HUMAN
θ value	θ > 10 (rank : 1135)	NC score	0.079842 (rank : 828)
Query Neighborhood Hits	600	Target Neighborhood Hits	239	Shared Neighborhood Hits	119
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 1136)	NC score	0.092772 (rank : 736)
Query Neighborhood Hits	600	Target Neighborhood Hits	244	Shared Neighborhood Hits	133
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEC_HUMAN
θ value	θ > 10 (rank : 1137)	NC score	0.052167 (rank : 1039)
Query Neighborhood Hits	600	Target Neighborhood Hits	1006	Shared Neighborhood Hits	55
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 1138)	NC score	0.051961 (rank : 1043)
Query Neighborhood Hits	600	Target Neighborhood Hits	1006	Shared Neighborhood Hits	55
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEFF2_HUMAN
θ value	θ > 10 (rank : 1139)	NC score	0.153641 (rank : 526)
Query Neighborhood Hits	600	Target Neighborhood Hits	211	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 1140)	NC score	0.156867 (rank : 516)
Query Neighborhood Hits	600	Target Neighborhood Hits	214	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEX14_HUMAN
θ value	θ > 10 (rank : 1141)	NC score	0.050157 (rank : 1067)
Query Neighborhood Hits	600	Target Neighborhood Hits	1103	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TLL1_HUMAN
θ value	θ > 10 (rank : 1142)	NC score	0.063571 (rank : 925)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	95
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 1143)	NC score	0.066606 (rank : 911)
Query Neighborhood Hits	600	Target Neighborhood Hits	237	Shared Neighborhood Hits	98
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 1144)	NC score	0.064979 (rank : 919)
Query Neighborhood Hits	600	Target Neighborhood Hits	241	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 1145)	NC score	0.060710 (rank : 950)
Query Neighborhood Hits	600	Target Neighborhood Hits	240	Shared Neighborhood Hits	99
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TMIGD_HUMAN
θ value	θ > 10 (rank : 1146)	NC score	0.183939 (rank : 445)
Query Neighborhood Hits	600	Target Neighborhood Hits	240	Shared Neighborhood Hits	83
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TMIGD_MOUSE
θ value	θ > 10 (rank : 1147)	NC score	0.184046 (rank : 443)
Query Neighborhood Hits	600	Target Neighborhood Hits	234	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TNK1_HUMAN
θ value	θ > 10 (rank : 1148)	NC score	0.061405 (rank : 944)
Query Neighborhood Hits	600	Target Neighborhood Hits	815	Shared Neighborhood Hits	54
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TNK1_MOUSE
θ value	θ > 10 (rank : 1149)	NC score	0.060029 (rank : 957)
Query Neighborhood Hits	600	Target Neighborhood Hits	806	Shared Neighborhood Hits	56
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TNR18_HUMAN
θ value	θ > 10 (rank : 1150)	NC score	0.053440 (rank : 1023)
Query Neighborhood Hits	600	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR1B_MOUSE
θ value	θ > 10 (rank : 1151)	NC score	0.055039 (rank : 1000)
Query Neighborhood Hits	600	Target Neighborhood Hits	123	Shared Neighborhood Hits	58
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR21_MOUSE
θ value	θ > 10 (rank : 1152)	NC score	0.055924 (rank : 992)
Query Neighborhood Hits	600	Target Neighborhood Hits	108	Shared Neighborhood Hits	60
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR26_MOUSE
θ value	θ > 10 (rank : 1153)	NC score	0.097187 (rank : 713)
Query Neighborhood Hits	600	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR3_HUMAN
θ value	θ > 10 (rank : 1154)	NC score	0.115330 (rank : 637)
Query Neighborhood Hits	600	Target Neighborhood Hits	145	Shared Neighborhood Hits	72
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR5_HUMAN
θ value	θ > 10 (rank : 1155)	NC score	0.085277 (rank : 799)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	70
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR6B_HUMAN
θ value	θ > 10 (rank : 1156)	NC score	0.093289 (rank : 734)
Query Neighborhood Hits	600	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_HUMAN
θ value	θ > 10 (rank : 1157)	NC score	0.072853 (rank : 861)
Query Neighborhood Hits	600	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	θ > 10 (rank : 1158)	NC score	0.089458 (rank : 767)
Query Neighborhood Hits	600	Target Neighborhood Hits	99	Shared Neighborhood Hits	66
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 1159)	NC score	0.106006 (rank : 674)
Query Neighborhood Hits	600	Target Neighborhood Hits	208	Shared Neighborhood Hits	84
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TPA_HUMAN
θ value	θ > 10 (rank : 1160)	NC score	0.050106 (rank : 1068)
Query Neighborhood Hits	600	Target Neighborhood Hits	324	Shared Neighborhood Hits	110
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 1161)	NC score	0.053355 (rank : 1024)
Query Neighborhood Hits	600	Target Neighborhood Hits	335	Shared Neighborhood Hits	113
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TR10B_MOUSE
θ value	θ > 10 (rank : 1162)	NC score	0.077763 (rank : 841)
Query Neighborhood Hits	600	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR11B_HUMAN
θ value	θ > 10 (rank : 1163)	NC score	0.059346 (rank : 970)
Query Neighborhood Hits	600	Target Neighborhood Hits	92	Shared Neighborhood Hits	55
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR11B_MOUSE
θ value	θ > 10 (rank : 1164)	NC score	0.067420 (rank : 905)
Query Neighborhood Hits	600	Target Neighborhood Hits	95	Shared Neighborhood Hits	57
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR19L_HUMAN
θ value	θ > 10 (rank : 1165)	NC score	0.084397 (rank : 807)
Query Neighborhood Hits	600	Target Neighborhood Hits	99	Shared Neighborhood Hits	53
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	θ > 10 (rank : 1166)	NC score	0.087184 (rank : 792)
Query Neighborhood Hits	600	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TRBM_HUMAN
θ value	θ > 10 (rank : 1167)	NC score	0.290943 (rank : 261)
Query Neighborhood Hits	600	Target Neighborhood Hits	339	Shared Neighborhood Hits	189
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 1168)	NC score	0.281321 (rank : 274)
Query Neighborhood Hits	600	Target Neighborhood Hits	361	Shared Neighborhood Hits	202
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRI42_HUMAN
θ value	θ > 10 (rank : 1169)	NC score	0.055810 (rank : 993)
Query Neighborhood Hits	600	Target Neighborhood Hits	283	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
θ value	θ > 10 (rank : 1170)	NC score	0.054452 (rank : 1005)
Query Neighborhood Hits	600	Target Neighborhood Hits	316	Shared Neighborhood Hits	88
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRIO_HUMAN
θ value	θ > 10 (rank : 1171)	NC score	0.059353 (rank : 969)
Query Neighborhood Hits	600	Target Neighborhood Hits	1580	Shared Neighborhood Hits	132
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TXK_HUMAN
θ value	θ > 10 (rank : 1172)	NC score	0.053041 (rank : 1026)
Query Neighborhood Hits	600	Target Neighborhood Hits	971	Shared Neighborhood Hits	56
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 1173)	NC score	0.053637 (rank : 1019)
Query Neighborhood Hits	600	Target Neighborhood Hits	980	Shared Neighborhood Hits	56
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

UNC5A_HUMAN
θ value	θ > 10 (rank : 1174)	NC score	0.094143 (rank : 728)
Query Neighborhood Hits	600	Target Neighborhood Hits	198	Shared Neighborhood Hits	72
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5A_MOUSE
θ value	θ > 10 (rank : 1175)	NC score	0.084637 (rank : 804)
Query Neighborhood Hits	600	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 1176)	NC score	0.087813 (rank : 782)
Query Neighborhood Hits	600	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 1177)	NC score	0.087169 (rank : 793)
Query Neighborhood Hits	600	Target Neighborhood Hits	226	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 1178)	NC score	0.089727 (rank : 765)
Query Neighborhood Hits	600	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 1179)	NC score	0.089670 (rank : 766)
Query Neighborhood Hits	600	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 1180)	NC score	0.102089 (rank : 687)
Query Neighborhood Hits	600	Target Neighborhood Hits	267	Shared Neighborhood Hits	88
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 1181)	NC score	0.105555 (rank : 675)
Query Neighborhood Hits	600	Target Neighborhood Hits	268	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UROL1_HUMAN
θ value	θ > 10 (rank : 1182)	NC score	0.084881 (rank : 802)
Query Neighborhood Hits	600	Target Neighborhood Hits	213	Shared Neighborhood Hits	97
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 1183)	NC score	0.099715 (rank : 697)
Query Neighborhood Hits	600	Target Neighborhood Hits	235	Shared Neighborhood Hits	114
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

VASN_HUMAN
θ value	θ > 10 (rank : 1184)	NC score	0.080423 (rank : 827)
Query Neighborhood Hits	600	Target Neighborhood Hits	449	Shared Neighborhood Hits	115
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VASN_MOUSE
θ value	θ > 10 (rank : 1185)	NC score	0.075186 (rank : 852)
Query Neighborhood Hits	600	Target Neighborhood Hits	426	Shared Neighborhood Hits	110
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VCAM1_HUMAN
θ value	θ > 10 (rank : 1186)	NC score	0.190146 (rank : 421)
Query Neighborhood Hits	600	Target Neighborhood Hits	352	Shared Neighborhood Hits	82
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

VCAM1_MOUSE
θ value	θ > 10 (rank : 1187)	NC score	0.193284 (rank : 412)
Query Neighborhood Hits	600	Target Neighborhood Hits	320	Shared Neighborhood Hits	80
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

VEGFC_MOUSE
θ value	θ > 10 (rank : 1188)	NC score	0.111695 (rank : 649)
Query Neighborhood Hits	600	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VGFR1_HUMAN
θ value	θ > 10 (rank : 1189)	NC score	0.136712 (rank : 566)
Query Neighborhood Hits	600	Target Neighborhood Hits	1109	Shared Neighborhood Hits	123
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

VGFR1_MOUSE
θ value	θ > 10 (rank : 1190)	NC score	0.136123 (rank : 568)
Query Neighborhood Hits	600	Target Neighborhood Hits	1118	Shared Neighborhood Hits	124
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

VGFR2_HUMAN
θ value	θ > 10 (rank : 1191)	NC score	0.130496 (rank : 586)
Query Neighborhood Hits	600	Target Neighborhood Hits	1103	Shared Neighborhood Hits	123
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

VGFR2_MOUSE
θ value	θ > 10 (rank : 1192)	NC score	0.129771 (rank : 591)
Query Neighborhood Hits	600	Target Neighborhood Hits	1089	Shared Neighborhood Hits	123
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

VGFR3_HUMAN
θ value	θ > 10 (rank : 1193)	NC score	0.114159 (rank : 642)
Query Neighborhood Hits	600	Target Neighborhood Hits	1037	Shared Neighborhood Hits	123
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VGFR3_MOUSE
θ value	θ > 10 (rank : 1194)	NC score	0.113326 (rank : 644)
Query Neighborhood Hits	600	Target Neighborhood Hits	1056	Shared Neighborhood Hits	126
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VLDLR_HUMAN
θ value	θ > 10 (rank : 1195)	NC score	0.243103 (rank : 331)
Query Neighborhood Hits	600	Target Neighborhood Hits	383	Shared Neighborhood Hits	200
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VSIG2_HUMAN
θ value	θ > 10 (rank : 1196)	NC score	0.157430 (rank : 515)
Query Neighborhood Hits	600	Target Neighborhood Hits	321	Shared Neighborhood Hits	79
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG2_MOUSE
θ value	θ > 10 (rank : 1197)	NC score	0.148639 (rank : 539)
Query Neighborhood Hits	600	Target Neighborhood Hits	316	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG4_HUMAN
θ value	θ > 10 (rank : 1198)	NC score	0.130954 (rank : 584)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

VWF_MOUSE
θ value	θ > 10 (rank : 1199)	NC score	0.178316 (rank : 456)
Query Neighborhood Hits	600	Target Neighborhood Hits	381	Shared Neighborhood Hits	179
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WFDC3_HUMAN
θ value	θ > 10 (rank : 1200)	NC score	0.074355 (rank : 854)
Query Neighborhood Hits	600	Target Neighborhood Hits	138	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

YES_HUMAN
θ value	θ > 10 (rank : 1201)	NC score	0.051987 (rank : 1042)
Query Neighborhood Hits	600	Target Neighborhood Hits	1059	Shared Neighborhood Hits	60
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	θ > 10 (rank : 1202)	NC score	0.051859 (rank : 1045)
Query Neighborhood Hits	600	Target Neighborhood Hits	1052	Shared Neighborhood Hits	59
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

ZAP70_HUMAN
θ value	θ > 10 (rank : 1203)	NC score	0.057814 (rank : 981)
Query Neighborhood Hits	600	Target Neighborhood Hits	893	Shared Neighborhood Hits	54
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 1204)	NC score	0.057700 (rank : 983)
Query Neighborhood Hits	600	Target Neighborhood Hits	905	Shared Neighborhood Hits	55
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZNFX1_HUMAN
θ value	θ > 10 (rank : 1205)	NC score	0.067902 (rank : 900)
Query Neighborhood Hits	600	Target Neighborhood Hits	308	Shared Neighborhood Hits	84
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	θ > 10 (rank : 1206)	NC score	0.070076 (rank : 882)
Query Neighborhood Hits	600	Target Neighborhood Hits	407	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

Hits sorted by NC score

USH2A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	600	Target Neighborhood Hits	600	Shared Neighborhood Hits	600
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
NC score	0.979454 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	600	Target Neighborhood Hits	626	Shared Neighborhood Hits	444
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LAMA5_MOUSE
NC score	0.762848 (rank : 3)	θ value	6.24247e-110 (rank : 3)
Query Neighborhood Hits	600	Target Neighborhood Hits	828	Shared Neighborhood Hits	316
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB3_MOUSE
NC score	0.760799 (rank : 4)	θ value	3.82246e-75 (rank : 8)
Query Neighborhood Hits	600	Target Neighborhood Hits	444	Shared Neighborhood Hits	218
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMA5_HUMAN
NC score	0.755775 (rank : 5)	θ value	1.81628e-109 (rank : 4)
Query Neighborhood Hits	600	Target Neighborhood Hits	976	Shared Neighborhood Hits	317
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB3_HUMAN
NC score	0.753578 (rank : 6)	θ value	1.35638e-80 (rank : 6)
Query Neighborhood Hits	600	Target Neighborhood Hits	461	Shared Neighborhood Hits	196
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMC3_HUMAN
NC score	0.751322 (rank : 7)	θ value	1.19377e-60 (rank : 19)
Query Neighborhood Hits	600	Target Neighborhood Hits	588	Shared Neighborhood Hits	283
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
NC score	0.749701 (rank : 8)	θ value	2.17557e-62 (rank : 18)
Query Neighborhood Hits	600	Target Neighborhood Hits	624	Shared Neighborhood Hits	274
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA1_HUMAN
NC score	0.749325 (rank : 9)	θ value	1.66191e-70 (rank : 15)
Query Neighborhood Hits	600	Target Neighborhood Hits	804	Shared Neighborhood Hits	318
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_MOUSE
NC score	0.746867 (rank : 10)	θ value	3.23591e-74 (rank : 10)
Query Neighborhood Hits	600	Target Neighborhood Hits	722	Shared Neighborhood Hits	278
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB2_HUMAN
NC score	0.746357 (rank : 11)	θ value	7.97034e-73 (rank : 13)
Query Neighborhood Hits	600	Target Neighborhood Hits	692	Shared Neighborhood Hits	273
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMA1_MOUSE
NC score	0.741889 (rank : 12)	θ value	1.50314e-71 (rank : 14)
Query Neighborhood Hits	600	Target Neighborhood Hits	838	Shared Neighborhood Hits	313
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MEGF9_HUMAN
NC score	0.738328 (rank : 13)	θ value	6.81017e-40 (rank : 30)
Query Neighborhood Hits	600	Target Neighborhood Hits	557	Shared Neighborhood Hits	272
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NET4_HUMAN
NC score	0.730746 (rank : 14)	θ value	3.2585e-50 (rank : 21)
Query Neighborhood Hits	600	Target Neighborhood Hits	191	Shared Neighborhood Hits	163
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
NC score	0.728201 (rank : 15)	θ value	1.97686e-47 (rank : 25)
Query Neighborhood Hits	600	Target Neighborhood Hits	180	Shared Neighborhood Hits	157
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NET2_MOUSE
NC score	0.720345 (rank : 16)	θ value	6.15952e-41 (rank : 28)
Query Neighborhood Hits	600	Target Neighborhood Hits	193	Shared Neighborhood Hits	160
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET2_HUMAN
NC score	0.718139 (rank : 17)	θ value	5.21438e-40 (rank : 29)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	153
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

LAMA3_MOUSE
NC score	0.715353 (rank : 18)	θ value	3.56116e-89 (rank : 5)
Query Neighborhood Hits	600	Target Neighborhood Hits	859	Shared Neighborhood Hits	284
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

NTNG2_HUMAN
NC score	0.711321 (rank : 19)	θ value	5.40856e-29 (rank : 39)
Query Neighborhood Hits	600	Target Neighborhood Hits	276	Shared Neighborhood Hits	188
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

MEGF9_MOUSE
NC score	0.710472 (rank : 20)	θ value	5.39604e-37 (rank : 31)
Query Neighborhood Hits	600	Target Neighborhood Hits	896	Shared Neighborhood Hits	274
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NTNG1_HUMAN
NC score	0.710372 (rank : 21)	θ value	2.42779e-29 (rank : 36)
Query Neighborhood Hits	600	Target Neighborhood Hits	247	Shared Neighborhood Hits	179
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMB1_MOUSE
NC score	0.710263 (rank : 22)	θ value	3.69378e-78 (rank : 7)
Query Neighborhood Hits	600	Target Neighborhood Hits	919	Shared Neighborhood Hits	254
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NTNG1_MOUSE
NC score	0.710106 (rank : 23)	θ value	2.42779e-29 (rank : 37)
Query Neighborhood Hits	600	Target Neighborhood Hits	246	Shared Neighborhood Hits	182
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NET1_HUMAN
NC score	0.706051 (rank : 24)	θ value	7.25919e-50 (rank : 22)
Query Neighborhood Hits	600	Target Neighborhood Hits	149	Shared Neighborhood Hits	125
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
NC score	0.705689 (rank : 25)	θ value	8.57503e-51 (rank : 20)
Query Neighborhood Hits	600	Target Neighborhood Hits	151	Shared Neighborhood Hits	126
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

LAMC1_MOUSE
NC score	0.703786 (rank : 26)	θ value	8.83269e-64 (rank : 17)
Query Neighborhood Hits	600	Target Neighborhood Hits	856	Shared Neighborhood Hits	272
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA2_HUMAN
NC score	0.701250 (rank : 27)	θ value	7.20884e-74 (rank : 11)
Query Neighborhood Hits	600	Target Neighborhood Hits	1092	Shared Neighborhood Hits	314
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NTNG2_MOUSE
NC score	0.689380 (rank : 28)	θ value	2.35696e-16 (rank : 74)
Query Neighborhood Hits	600	Target Neighborhood Hits	276	Shared Neighborhood Hits	190
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMC2_MOUSE
NC score	0.686187 (rank : 29)	θ value	4.01107e-24 (rank : 54)
Query Neighborhood Hits	600	Target Neighborhood Hits	614	Shared Neighborhood Hits	270
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC1_HUMAN
NC score	0.683386 (rank : 30)	θ value	1.2325e-65 (rank : 16)
Query Neighborhood Hits	600	Target Neighborhood Hits	922	Shared Neighborhood Hits	270
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMB1_HUMAN
NC score	0.683380 (rank : 31)	θ value	2.47765e-74 (rank : 9)
Query Neighborhood Hits	600	Target Neighborhood Hits	1018	Shared Neighborhood Hits	257
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMA2_MOUSE
NC score	0.676300 (rank : 32)	θ value	1.22964e-73 (rank : 12)
Query Neighborhood Hits	600	Target Neighborhood Hits	1198	Shared Neighborhood Hits	312
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC2_HUMAN
NC score	0.661191 (rank : 33)	θ value	9.87957e-23 (rank : 56)
Query Neighborhood Hits	600	Target Neighborhood Hits	715	Shared Neighborhood Hits	264
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

SREC2_MOUSE
NC score	0.647650 (rank : 34)	θ value	3.87602e-27 (rank : 45)
Query Neighborhood Hits	600	Target Neighborhood Hits	605	Shared Neighborhood Hits	273
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC2_HUMAN
NC score	0.647502 (rank : 35)	θ value	7.06379e-29 (rank : 40)
Query Neighborhood Hits	600	Target Neighborhood Hits	645	Shared Neighborhood Hits	276
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LAMA4_MOUSE
NC score	0.644226 (rank : 36)	θ value	6.40375e-22 (rank : 57)
Query Neighborhood Hits	600	Target Neighborhood Hits	584	Shared Neighborhood Hits	211
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

SREC_HUMAN
NC score	0.637633 (rank : 37)	θ value	5.59698e-26 (rank : 47)
Query Neighborhood Hits	600	Target Neighborhood Hits	645	Shared Neighborhood Hits	279
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

PGBM_MOUSE
NC score	0.637152 (rank : 38)	θ value	4.15078e-21 (rank : 59)
Query Neighborhood Hits	600	Target Neighborhood Hits	1073	Shared Neighborhood Hits	375
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

AGRIN_HUMAN
NC score	0.634670 (rank : 39)	θ value	5.07402e-19 (rank : 64)
Query Neighborhood Hits	600	Target Neighborhood Hits	582	Shared Neighborhood Hits	271
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

PGBM_HUMAN
NC score	0.628147 (rank : 40)	θ value	6.40375e-22 (rank : 58)
Query Neighborhood Hits	600	Target Neighborhood Hits	1113	Shared Neighborhood Hits	378
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LAMA3_HUMAN
NC score	0.627536 (rank : 41)	θ value	3.51386e-20 (rank : 62)
Query Neighborhood Hits	600	Target Neighborhood Hits	760	Shared Neighborhood Hits	255
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA4_HUMAN
NC score	0.610658 (rank : 42)	θ value	5.79196e-23 (rank : 55)
Query Neighborhood Hits	600	Target Neighborhood Hits	708	Shared Neighborhood Hits	212
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TENA_HUMAN
NC score	0.595849 (rank : 43)	θ value	6.20254e-17 (rank : 72)
Query Neighborhood Hits	600	Target Neighborhood Hits	631	Shared Neighborhood Hits	372
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENX_HUMAN
NC score	0.593914 (rank : 44)	θ value	3.40345e-15 (rank : 81)
Query Neighborhood Hits	600	Target Neighborhood Hits	789	Shared Neighborhood Hits	385
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TENA_MOUSE
NC score	0.586185 (rank : 45)	θ value	4.29542e-18 (rank : 69)
Query Neighborhood Hits	600	Target Neighborhood Hits	596	Shared Neighborhood Hits	364
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

ITB4_HUMAN
NC score	0.580530 (rank : 46)	θ value	6.87365e-08 (rank : 152)
Query Neighborhood Hits	600	Target Neighborhood Hits	458	Shared Neighborhood Hits	336
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

MEGF8_HUMAN
NC score	0.577796 (rank : 47)	θ value	5.62301e-10 (rank : 116)
Query Neighborhood Hits	600	Target Neighborhood Hits	528	Shared Neighborhood Hits	260
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF6_HUMAN
NC score	0.569891 (rank : 48)	θ value	1.6247e-33 (rank : 33)
Query Neighborhood Hits	600	Target Neighborhood Hits	671	Shared Neighborhood Hits	305
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF8_MOUSE
NC score	0.568686 (rank : 49)	θ value	4.30538e-10 (rank : 114)
Query Neighborhood Hits	600	Target Neighborhood Hits	520	Shared Neighborhood Hits	255
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KRA51_HUMAN
NC score	0.567188 (rank : 50)	θ value	2.44474e-05 (rank : 214)
Query Neighborhood Hits	600	Target Neighborhood Hits	288	Shared Neighborhood Hits	168
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
NC score	0.535683 (rank : 51)	θ value	0.00134147 (rank : 267)
Query Neighborhood Hits	600	Target Neighborhood Hits	331	Shared Neighborhood Hits	197
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA59_HUMAN
NC score	0.520426 (rank : 52)	θ value	0.00035302 (rank : 249)
Query Neighborhood Hits	600	Target Neighborhood Hits	310	Shared Neighborhood Hits	164
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

TENR_MOUSE
NC score	0.520205 (rank : 53)	θ value	2.0648e-12 (rank : 95)
Query Neighborhood Hits	600	Target Neighborhood Hits	531	Shared Neighborhood Hits	347
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

JAG1_MOUSE
NC score	0.520051 (rank : 54)	θ value	6.62687e-19 (rank : 65)
Query Neighborhood Hits	600	Target Neighborhood Hits	518	Shared Neighborhood Hits	266
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

TENR_HUMAN
NC score	0.519966 (rank : 55)	θ value	1.02475e-11 (rank : 99)
Query Neighborhood Hits	600	Target Neighborhood Hits	526	Shared Neighborhood Hits	349
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

DLL4_MOUSE
NC score	0.517857 (rank : 56)	θ value	2.69671e-12 (rank : 96)
Query Neighborhood Hits	600	Target Neighborhood Hits	440	Shared Neighborhood Hits	255
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

JAG1_HUMAN
NC score	0.517139 (rank : 57)	θ value	1.68911e-14 (rank : 86)
Query Neighborhood Hits	600	Target Neighborhood Hits	514	Shared Neighborhood Hits	266
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

FNDC3_HUMAN
NC score	0.516939 (rank : 58)	θ value	2.05525e-28 (rank : 41)
Query Neighborhood Hits	600	Target Neighborhood Hits	196	Shared Neighborhood Hits	169
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
NC score	0.515133 (rank : 59)	θ value	5.06226e-27 (rank : 46)
Query Neighborhood Hits	600	Target Neighborhood Hits	207	Shared Neighborhood Hits	168
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

JAG2_HUMAN
NC score	0.512297 (rank : 60)	θ value	3.76295e-14 (rank : 87)
Query Neighborhood Hits	600	Target Neighborhood Hits	491	Shared Neighborhood Hits	254
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
NC score	0.511183 (rank : 61)	θ value	8.95645e-16 (rank : 76)
Query Neighborhood Hits	600	Target Neighborhood Hits	504	Shared Neighborhood Hits	257
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DLL4_HUMAN
NC score	0.511095 (rank : 62)	θ value	3.29651e-10 (rank : 111)
Query Neighborhood Hits	600	Target Neighborhood Hits	435	Shared Neighborhood Hits	251
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLK_HUMAN
NC score	0.510241 (rank : 63)	θ value	1.09739e-05 (rank : 208)
Query Neighborhood Hits	600	Target Neighborhood Hits	401	Shared Neighborhood Hits	249
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

ATRN_MOUSE
NC score	0.507925 (rank : 64)	θ value	1.33837e-11 (rank : 100)
Query Neighborhood Hits	600	Target Neighborhood Hits	519	Shared Neighborhood Hits	230
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

ATRN_HUMAN
NC score	0.507136 (rank : 65)	θ value	1.02475e-11 (rank : 98)
Query Neighborhood Hits	600	Target Neighborhood Hits	525	Shared Neighborhood Hits	236
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

DLL1_HUMAN
NC score	0.506011 (rank : 66)	θ value	5.62301e-10 (rank : 115)
Query Neighborhood Hits	600	Target Neighborhood Hits	455	Shared Neighborhood Hits	256
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
NC score	0.503784 (rank : 67)	θ value	9.59137e-10 (rank : 119)
Query Neighborhood Hits	600	Target Neighborhood Hits	456	Shared Neighborhood Hits	261
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

KRA55_HUMAN
NC score	0.502807 (rank : 68)	θ value	0.00298849 (rank : 286)
Query Neighborhood Hits	600	Target Neighborhood Hits	257	Shared Neighborhood Hits	155
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

DLK_MOUSE
NC score	0.502216 (rank : 69)	θ value	7.1131e-05 (rank : 224)
Query Neighborhood Hits	600	Target Neighborhood Hits	374	Shared Neighborhood Hits	236
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

KRA54_HUMAN
NC score	0.501430 (rank : 70)	θ value	0.00228821 (rank : 281)
Query Neighborhood Hits	600	Target Neighborhood Hits	270	Shared Neighborhood Hits	152
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

WIF1_MOUSE
NC score	0.500567 (rank : 71)	θ value	9.29e-05 (rank : 234)
Query Neighborhood Hits	600	Target Neighborhood Hits	393	Shared Neighborhood Hits	236
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CRUM1_HUMAN
NC score	0.500081 (rank : 72)	θ value	4.45536e-07 (rank : 175)
Query Neighborhood Hits	600	Target Neighborhood Hits	457	Shared Neighborhood Hits	245
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DNER_MOUSE
NC score	0.500016 (rank : 73)	θ value	1.38499e-08 (rank : 142)
Query Neighborhood Hits	600	Target Neighborhood Hits	413	Shared Neighborhood Hits	232
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DNER_HUMAN
NC score	0.499546 (rank : 74)	θ value	4.76016e-09 (rank : 131)
Query Neighborhood Hits	600	Target Neighborhood Hits	460	Shared Neighborhood Hits	237
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

CRUM1_MOUSE
NC score	0.499162 (rank : 75)	θ value	4.1701e-05 (rank : 217)
Query Neighborhood Hits	600	Target Neighborhood Hits	444	Shared Neighborhood Hits	241
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
NC score	0.498163 (rank : 76)	θ value	1.63604e-09 (rank : 123)
Query Neighborhood Hits	600	Target Neighborhood Hits	453	Shared Neighborhood Hits	252
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

KRA57_HUMAN
NC score	0.495233 (rank : 77)	θ value	0.0193708 (rank : 318)
Query Neighborhood Hits	600	Target Neighborhood Hits	269	Shared Neighborhood Hits	156
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

WIF1_HUMAN
NC score	0.494518 (rank : 78)	θ value	5.44631e-05 (rank : 223)
Query Neighborhood Hits	600	Target Neighborhood Hits	392	Shared Neighborhood Hits	238
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

KRA58_HUMAN
NC score	0.493479 (rank : 79)	θ value	0.0193708 (rank : 319)
Query Neighborhood Hits	600	Target Neighborhood Hits	324	Shared Neighborhood Hits	181
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

DLL3_HUMAN
NC score	0.490779 (rank : 80)	θ value	0.00298849 (rank : 282)
Query Neighborhood Hits	600	Target Neighborhood Hits	419	Shared Neighborhood Hits	239
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

NAGPA_MOUSE
NC score	0.489912 (rank : 81)	θ value	0.000158464 (rank : 237)
Query Neighborhood Hits	600	Target Neighborhood Hits	308	Shared Neighborhood Hits	206
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

STAB1_HUMAN
NC score	0.488208 (rank : 82)	θ value	2.13673e-09 (rank : 124)
Query Neighborhood Hits	600	Target Neighborhood Hits	546	Shared Neighborhood Hits	281
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_MOUSE
NC score	0.485047 (rank : 83)	θ value	5.62301e-10 (rank : 117)
Query Neighborhood Hits	600	Target Neighborhood Hits	528	Shared Neighborhood Hits	286
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

EGFL9_HUMAN
NC score	0.484461 (rank : 84)	θ value	0.00298849 (rank : 283)
Query Neighborhood Hits	600	Target Neighborhood Hits	365	Shared Neighborhood Hits	236
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

DLL3_MOUSE
NC score	0.484389 (rank : 85)	θ value	0.0193708 (rank : 315)
Query Neighborhood Hits	600	Target Neighborhood Hits	399	Shared Neighborhood Hits	237
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

TENN_MOUSE
NC score	0.483132 (rank : 86)	θ value	1.74796e-11 (rank : 103)
Query Neighborhood Hits	600	Target Neighborhood Hits	484	Shared Neighborhood Hits	332
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

STAB2_HUMAN
NC score	0.482987 (rank : 87)	θ value	4.76016e-09 (rank : 134)
Query Neighborhood Hits	600	Target Neighborhood Hits	534	Shared Neighborhood Hits	274
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB1_MOUSE
NC score	0.481076 (rank : 88)	θ value	4.45536e-07 (rank : 177)
Query Neighborhood Hits	600	Target Neighborhood Hits	566	Shared Neighborhood Hits	284
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

NOTC1_MOUSE
NC score	0.478617 (rank : 89)	θ value	6.62687e-19 (rank : 66)
Query Neighborhood Hits	600	Target Neighborhood Hits	916	Shared Neighborhood Hits	275
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

EGFL9_MOUSE
NC score	0.475756 (rank : 90)	θ value	0.00228821 (rank : 278)
Query Neighborhood Hits	600	Target Neighborhood Hits	379	Shared Neighborhood Hits	238
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

NAGPA_HUMAN
NC score	0.475429 (rank : 91)	θ value	0.00175202 (rank : 274)
Query Neighborhood Hits	600	Target Neighborhood Hits	282	Shared Neighborhood Hits	195
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

SDK2_MOUSE
NC score	0.471751 (rank : 92)	θ value	7.25919e-50 (rank : 23)
Query Neighborhood Hits	600	Target Neighborhood Hits	480	Shared Neighborhood Hits	185
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

NOTC1_HUMAN
NC score	0.468292 (rank : 93)	θ value	5.99374e-20 (rank : 63)
Query Neighborhood Hits	600	Target Neighborhood Hits	906	Shared Neighborhood Hits	274
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SDK2_HUMAN
NC score	0.468003 (rank : 94)	θ value	1.23823e-49 (rank : 24)
Query Neighborhood Hits	600	Target Neighborhood Hits	495	Shared Neighborhood Hits	185
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_MOUSE
NC score	0.466935 (rank : 95)	θ value	7.51208e-47 (rank : 27)
Query Neighborhood Hits	600	Target Neighborhood Hits	495	Shared Neighborhood Hits	184
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

NOTC3_HUMAN
NC score	0.466021 (rank : 96)	θ value	1.2077e-20 (rank : 61)
Query Neighborhood Hits	600	Target Neighborhood Hits	1062	Shared Neighborhood Hits	293
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
NC score	0.465021 (rank : 97)	θ value	9.24701e-21 (rank : 60)
Query Neighborhood Hits	600	Target Neighborhood Hits	975	Shared Neighborhood Hits	280
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SDK1_HUMAN
NC score	0.463937 (rank : 98)	θ value	3.37202e-47 (rank : 26)
Query Neighborhood Hits	600	Target Neighborhood Hits	511	Shared Neighborhood Hits	183
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

TENN_HUMAN
NC score	0.461393 (rank : 99)	θ value	2.13673e-09 (rank : 125)
Query Neighborhood Hits	600	Target Neighborhood Hits	453	Shared Neighborhood Hits	315
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

FINC_MOUSE
NC score	0.460527 (rank : 100)	θ value	3.07116e-24 (rank : 53)
Query Neighborhood Hits	600	Target Neighborhood Hits	309	Shared Neighborhood Hits	194
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FINC_HUMAN
NC score	0.458326 (rank : 101)	θ value	2.77775e-25 (rank : 48)
Query Neighborhood Hits	600	Target Neighborhood Hits	302	Shared Neighborhood Hits	198
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

KR510_HUMAN
NC score	0.455229 (rank : 102)	θ value	0.21417 (rank : 375)
Query Neighborhood Hits	600	Target Neighborhood Hits	217	Shared Neighborhood Hits	123
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

NOTC2_MOUSE
NC score	0.454790 (rank : 103)	θ value	1.92812e-18 (rank : 67)
Query Neighborhood Hits	600	Target Neighborhood Hits	1069	Shared Neighborhood Hits	280
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KRA52_HUMAN
NC score	0.454278 (rank : 104)	θ value	0.0961366 (rank : 355)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	141
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

NOTC4_MOUSE
NC score	0.449921 (rank : 105)	θ value	2.69671e-12 (rank : 97)
Query Neighborhood Hits	600	Target Neighborhood Hits	872	Shared Neighborhood Hits	279
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC2_HUMAN
NC score	0.448848 (rank : 106)	θ value	2.43908e-13 (rank : 91)
Query Neighborhood Hits	600	Target Neighborhood Hits	1113	Shared Neighborhood Hits	290
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_HUMAN
NC score	0.448252 (rank : 107)	θ value	3.29651e-10 (rank : 112)
Query Neighborhood Hits	600	Target Neighborhood Hits	905	Shared Neighborhood Hits	284
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NEO1_MOUSE
NC score	0.447587 (rank : 108)	θ value	3.50572e-28 (rank : 42)
Query Neighborhood Hits	600	Target Neighborhood Hits	523	Shared Neighborhood Hits	184
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NEO1_HUMAN
NC score	0.447290 (rank : 109)	θ value	3.17079e-29 (rank : 38)
Query Neighborhood Hits	600	Target Neighborhood Hits	530	Shared Neighborhood Hits	184
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

CREL1_HUMAN
NC score	0.443972 (rank : 110)	θ value	9.29e-05 (rank : 229)
Query Neighborhood Hits	600	Target Neighborhood Hits	441	Shared Neighborhood Hits	222
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

KR511_HUMAN
NC score	0.440106 (rank : 111)	θ value	0.0563607 (rank : 345)
Query Neighborhood Hits	600	Target Neighborhood Hits	231	Shared Neighborhood Hits	129
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA56_HUMAN
NC score	0.439795 (rank : 112)	θ value	1.38821 (rank : 432)
Query Neighborhood Hits	600	Target Neighborhood Hits	207	Shared Neighborhood Hits	134
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

DCC_HUMAN
NC score	0.434107 (rank : 113)	θ value	6.18819e-25 (rank : 50)
Query Neighborhood Hits	600	Target Neighborhood Hits	583	Shared Neighborhood Hits	187
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

CREL1_MOUSE
NC score	0.425951 (rank : 114)	θ value	0.00020696 (rank : 239)
Query Neighborhood Hits	600	Target Neighborhood Hits	524	Shared Neighborhood Hits	235
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

DCC_MOUSE
NC score	0.423848 (rank : 115)	θ value	8.08199e-25 (rank : 51)
Query Neighborhood Hits	600	Target Neighborhood Hits	896	Shared Neighborhood Hits	197
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DSCL1_HUMAN
NC score	0.420727 (rank : 116)	θ value	3.62785e-25 (rank : 49)
Query Neighborhood Hits	600	Target Neighborhood Hits	589	Shared Neighborhood Hits	176
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

DSCAM_HUMAN
NC score	0.416455 (rank : 117)	θ value	1.73987e-27 (rank : 43)
Query Neighborhood Hits	600	Target Neighborhood Hits	524	Shared Neighborhood Hits	170
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

NRCAM_HUMAN
NC score	0.415137 (rank : 118)	θ value	5.8054e-15 (rank : 83)
Query Neighborhood Hits	600	Target Neighborhood Hits	439	Shared Neighborhood Hits	168
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
NC score	0.406950 (rank : 119)	θ value	8.38298e-14 (rank : 88)
Query Neighborhood Hits	600	Target Neighborhood Hits	432	Shared Neighborhood Hits	166
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

L1CAM_HUMAN
NC score	0.406819 (rank : 120)	θ value	1.86753e-13 (rank : 90)
Query Neighborhood Hits	600	Target Neighborhood Hits	457	Shared Neighborhood Hits	171
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

PTPRD_HUMAN
NC score	0.405558 (rank : 121)	θ value	1.01765e-35 (rank : 32)
Query Neighborhood Hits	600	Target Neighborhood Hits	485	Shared Neighborhood Hits	195
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
NC score	0.401711 (rank : 122)	θ value	6.38894e-30 (rank : 35)
Query Neighborhood Hits	600	Target Neighborhood Hits	491	Shared Neighborhood Hits	189
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

KR171_HUMAN
NC score	0.400957 (rank : 123)	θ value	1.06291 (rank : 422)
Query Neighborhood Hits	600	Target Neighborhood Hits	144	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

L1CAM_MOUSE
NC score	0.399815 (rank : 124)	θ value	5.43371e-13 (rank : 93)
Query Neighborhood Hits	600	Target Neighborhood Hits	457	Shared Neighborhood Hits	173
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LTBP4_MOUSE
NC score	0.398049 (rank : 125)	θ value	2.88788e-06 (rank : 196)
Query Neighborhood Hits	600	Target Neighborhood Hits	607	Shared Neighborhood Hits	259
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

ITB6_MOUSE
NC score	0.397378 (rank : 126)	θ value	5.44631e-05 (rank : 222)
Query Neighborhood Hits	600	Target Neighborhood Hits	341	Shared Neighborhood Hits	219
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

NFASC_HUMAN
NC score	0.396721 (rank : 127)	θ value	1.09485e-13 (rank : 89)
Query Neighborhood Hits	600	Target Neighborhood Hits	497	Shared Neighborhood Hits	174
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

PTPRF_HUMAN
NC score	0.396606 (rank : 128)	θ value	7.54701e-31 (rank : 34)
Query Neighborhood Hits	600	Target Neighborhood Hits	489	Shared Neighborhood Hits	188
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

FBN3_HUMAN
NC score	0.393882 (rank : 129)	θ value	0.000602161 (rank : 254)
Query Neighborhood Hits	600	Target Neighborhood Hits	543	Shared Neighborhood Hits	273
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

KR104_HUMAN
NC score	0.393313 (rank : 130)	θ value	0.000786445 (rank : 258)
Query Neighborhood Hits	600	Target Neighborhood Hits	313	Shared Neighborhood Hits	174
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

ITB7_MOUSE
NC score	0.393198 (rank : 131)	θ value	0.00102713 (rank : 263)
Query Neighborhood Hits	600	Target Neighborhood Hits	277	Shared Neighborhood Hits	199
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

LTBP2_MOUSE
NC score	0.393016 (rank : 132)	θ value	1.43324e-05 (rank : 210)
Query Neighborhood Hits	600	Target Neighborhood Hits	617	Shared Neighborhood Hits	274
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

ITB7_HUMAN
NC score	0.393011 (rank : 133)	θ value	0.000602161 (rank : 255)
Query Neighborhood Hits	600	Target Neighborhood Hits	290	Shared Neighborhood Hits	206
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

PTPRS_HUMAN
NC score	0.390875 (rank : 134)	θ value	1.05554e-24 (rank : 52)
Query Neighborhood Hits	600	Target Neighborhood Hits	472	Shared Neighborhood Hits	185
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

ITB6_HUMAN
NC score	0.390110 (rank : 135)	θ value	7.1131e-05 (rank : 225)
Query Neighborhood Hits	600	Target Neighborhood Hits	318	Shared Neighborhood Hits	211
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

FBN1_MOUSE
NC score	0.389954 (rank : 136)	θ value	1.43324e-05 (rank : 209)
Query Neighborhood Hits	600	Target Neighborhood Hits	563	Shared Neighborhood Hits	279
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

NELL1_HUMAN
NC score	0.389951 (rank : 137)	θ value	0.00390308 (rank : 292)
Query Neighborhood Hits	600	Target Neighborhood Hits	451	Shared Neighborhood Hits	246
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

LTBP2_HUMAN
NC score	0.388494 (rank : 138)	θ value	0.00298849 (rank : 287)
Query Neighborhood Hits	600	Target Neighborhood Hits	552	Shared Neighborhood Hits	269
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN1_HUMAN
NC score	0.388465 (rank : 139)	θ value	1.87187e-05 (rank : 212)
Query Neighborhood Hits	600	Target Neighborhood Hits	557	Shared Neighborhood Hits	283
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

ITB2_MOUSE
NC score	0.388137 (rank : 140)	θ value	0.000461057 (rank : 251)
Query Neighborhood Hits	600	Target Neighborhood Hits	326	Shared Neighborhood Hits	226
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

CHL1_HUMAN
NC score	0.387955 (rank : 141)	θ value	1.63604e-09 (rank : 122)
Query Neighborhood Hits	600	Target Neighborhood Hits	413	Shared Neighborhood Hits	154
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

FBN2_HUMAN
NC score	0.387363 (rank : 142)	θ value	8.40245e-06 (rank : 206)
Query Neighborhood Hits	600	Target Neighborhood Hits	560	Shared Neighborhood Hits	275
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

ITB5_MOUSE
NC score	0.386028 (rank : 143)	θ value	0.000270298 (rank : 246)
Query Neighborhood Hits	600	Target Neighborhood Hits	329	Shared Neighborhood Hits	222
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

FBN2_MOUSE
NC score	0.385864 (rank : 144)	θ value	8.40245e-06 (rank : 207)
Query Neighborhood Hits	600	Target Neighborhood Hits	549	Shared Neighborhood Hits	276
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

CNTN2_HUMAN
NC score	0.384890 (rank : 145)	θ value	3.63628e-17 (rank : 70)
Query Neighborhood Hits	600	Target Neighborhood Hits	440	Shared Neighborhood Hits	166
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN3_MOUSE
NC score	0.382684 (rank : 146)	θ value	6.64225e-11 (rank : 107)
Query Neighborhood Hits	600	Target Neighborhood Hits	447	Shared Neighborhood Hits	169
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN2_MOUSE
NC score	0.381610 (rank : 147)	θ value	1.16975e-15 (rank : 77)
Query Neighborhood Hits	600	Target Neighborhood Hits	450	Shared Neighborhood Hits	162
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN3_HUMAN
NC score	0.381403 (rank : 148)	θ value	1.133e-10 (rank : 108)
Query Neighborhood Hits	600	Target Neighborhood Hits	455	Shared Neighborhood Hits	170
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

PCSK5_MOUSE
NC score	0.380372 (rank : 149)	θ value	1.38499e-08 (rank : 143)
Query Neighborhood Hits	600	Target Neighborhood Hits	613	Shared Neighborhood Hits	290
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CHL1_MOUSE
NC score	0.380065 (rank : 150)	θ value	2.28291e-11 (rank : 104)
Query Neighborhood Hits	600	Target Neighborhood Hits	402	Shared Neighborhood Hits	150
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CRIM1_HUMAN
NC score	0.379594 (rank : 151)	θ value	4.45536e-07 (rank : 174)
Query Neighborhood Hits	600	Target Neighborhood Hits	362	Shared Neighborhood Hits	185
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ITB5_HUMAN
NC score	0.379014 (rank : 152)	θ value	0.000121331 (rank : 235)
Query Neighborhood Hits	600	Target Neighborhood Hits	310	Shared Neighborhood Hits	219
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

NFASC_MOUSE
NC score	0.376568 (rank : 153)	θ value	2.98157e-11 (rank : 106)
Query Neighborhood Hits	600	Target Neighborhood Hits	475	Shared Neighborhood Hits	163
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

MYOM1_HUMAN
NC score	0.374067 (rank : 154)	θ value	3.77169e-06 (rank : 200)
Query Neighborhood Hits	600	Target Neighborhood Hits	405	Shared Neighborhood Hits	162
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

CNTN5_HUMAN
NC score	0.372894 (rank : 155)	θ value	2.79066e-09 (rank : 126)
Query Neighborhood Hits	600	Target Neighborhood Hits	446	Shared Neighborhood Hits	163
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

KR107_HUMAN
NC score	0.371863 (rank : 156)	θ value	0.0431538 (rank : 341)
Query Neighborhood Hits	600	Target Neighborhood Hits	330	Shared Neighborhood Hits	184
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

ITB1_HUMAN
NC score	0.371507 (rank : 157)	θ value	7.59969e-07 (rank : 182)
Query Neighborhood Hits	600	Target Neighborhood Hits	298	Shared Neighborhood Hits	207
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

CNTN1_MOUSE
NC score	0.370815 (rank : 158)	θ value	4.0297e-08 (rank : 147)
Query Neighborhood Hits	600	Target Neighborhood Hits	422	Shared Neighborhood Hits	153
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

ITB1_MOUSE
NC score	0.370559 (rank : 159)	θ value	3.77169e-06 (rank : 198)
Query Neighborhood Hits	600	Target Neighborhood Hits	283	Shared Neighborhood Hits	197
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

NELL2_MOUSE
NC score	0.369903 (rank : 160)	θ value	0.00102713 (rank : 264)
Query Neighborhood Hits	600	Target Neighborhood Hits	436	Shared Neighborhood Hits	238
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

CNTN1_HUMAN
NC score	0.369870 (rank : 161)	θ value	8.97725e-08 (rank : 154)
Query Neighborhood Hits	600	Target Neighborhood Hits	431	Shared Neighborhood Hits	152
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

ZAN_MOUSE
NC score	0.369428 (rank : 162)	θ value	0.000602161 (rank : 257)
Query Neighborhood Hits	600	Target Neighborhood Hits	808	Shared Neighborhood Hits	311
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CNTN5_MOUSE
NC score	0.368136 (rank : 163)	θ value	8.11959e-09 (rank : 138)
Query Neighborhood Hits	600	Target Neighborhood Hits	434	Shared Neighborhood Hits	154
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

FRAS1_HUMAN
NC score	0.368014 (rank : 164)	θ value	8.97725e-08 (rank : 156)
Query Neighborhood Hits	600	Target Neighborhood Hits	759	Shared Neighborhood Hits	274
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ITB2_HUMAN
NC score	0.367414 (rank : 165)	θ value	0.0113563 (rank : 310)
Query Neighborhood Hits	600	Target Neighborhood Hits	282	Shared Neighborhood Hits	211
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

CNTN6_HUMAN
NC score	0.366047 (rank : 166)	θ value	1.69304e-06 (rank : 190)
Query Neighborhood Hits	600	Target Neighborhood Hits	422	Shared Neighborhood Hits	148
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

NELL2_HUMAN
NC score	0.364825 (rank : 167)	θ value	θ > 10 (rank : 976)
Query Neighborhood Hits	600	Target Neighborhood Hits	449	Shared Neighborhood Hits	242
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

CNTN4_MOUSE
NC score	0.364078 (rank : 168)	θ value	2.28291e-11 (rank : 105)
Query Neighborhood Hits	600	Target Neighborhood Hits	445	Shared Neighborhood Hits	150
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN4_HUMAN
NC score	0.363930 (rank : 169)	θ value	3.29651e-10 (rank : 110)
Query Neighborhood Hits	600	Target Neighborhood Hits	449	Shared Neighborhood Hits	150
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

NRX1A_HUMAN
NC score	0.363845 (rank : 170)	θ value	4.74913e-17 (rank : 71)
Query Neighborhood Hits	600	Target Neighborhood Hits	170	Shared Neighborhood Hits	110
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

SLIT1_MOUSE
NC score	0.361723 (rank : 171)	θ value	1.99992e-07 (rank : 167)
Query Neighborhood Hits	600	Target Neighborhood Hits	715	Shared Neighborhood Hits	245
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

CNTN6_MOUSE
NC score	0.360843 (rank : 172)	θ value	7.59969e-07 (rank : 179)
Query Neighborhood Hits	600	Target Neighborhood Hits	429	Shared Neighborhood Hits	147
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

NRX1A_MOUSE
NC score	0.359793 (rank : 173)	θ value	1.99529e-15 (rank : 79)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	109
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

ITB3_HUMAN
NC score	0.359429 (rank : 174)	θ value	0.0193708 (rank : 317)
Query Neighborhood Hits	600	Target Neighborhood Hits	325	Shared Neighborhood Hits	218
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LTBP3_MOUSE
NC score	0.359279 (rank : 175)	θ value	3.77169e-06 (rank : 199)
Query Neighborhood Hits	600	Target Neighborhood Hits	475	Shared Neighborhood Hits	249
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FRAS1_MOUSE
NC score	0.359259 (rank : 176)	θ value	4.76016e-09 (rank : 132)
Query Neighborhood Hits	600	Target Neighborhood Hits	747	Shared Neighborhood Hits	278
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LTBP3_HUMAN
NC score	0.358931 (rank : 177)	θ value	0.000121331 (rank : 236)
Query Neighborhood Hits	600	Target Neighborhood Hits	502	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

SCUB3_HUMAN
NC score	0.358334 (rank : 178)	θ value	2.36244e-08 (rank : 145)
Query Neighborhood Hits	600	Target Neighborhood Hits	428	Shared Neighborhood Hits	244
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

KR106_HUMAN
NC score	0.357677 (rank : 179)	θ value	0.125558 (rank : 362)
Query Neighborhood Hits	600	Target Neighborhood Hits	347	Shared Neighborhood Hits	194
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

NRX3A_HUMAN
NC score	0.357661 (rank : 180)	θ value	2.5182e-18 (rank : 68)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

SCUB3_MOUSE
NC score	0.357121 (rank : 181)	θ value	1.99992e-07 (rank : 166)
Query Neighborhood Hits	600	Target Neighborhood Hits	442	Shared Neighborhood Hits	250
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SLIT1_HUMAN
NC score	0.356699 (rank : 182)	θ value	0.000602161 (rank : 256)
Query Neighborhood Hits	600	Target Neighborhood Hits	700	Shared Neighborhood Hits	240
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

PUNC_HUMAN
NC score	0.356310 (rank : 183)	θ value	6.21693e-09 (rank : 136)
Query Neighborhood Hits	600	Target Neighborhood Hits	449	Shared Neighborhood Hits	152
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

SLIT2_HUMAN
NC score	0.356235 (rank : 184)	θ value	1.53129e-07 (rank : 163)
Query Neighborhood Hits	600	Target Neighborhood Hits	708	Shared Neighborhood Hits	239
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

MYOM2_HUMAN
NC score	0.356144 (rank : 185)	θ value	0.00665767 (rank : 304)
Query Neighborhood Hits	600	Target Neighborhood Hits	341	Shared Neighborhood Hits	150
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

ITB3_MOUSE
NC score	0.355579 (rank : 186)	θ value	0.000461057 (rank : 252)
Query Neighborhood Hits	600	Target Neighborhood Hits	319	Shared Neighborhood Hits	209
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

SORL_MOUSE
NC score	0.354705 (rank : 187)	θ value	9.92553e-07 (rank : 186)
Query Neighborhood Hits	600	Target Neighborhood Hits	439	Shared Neighborhood Hits	289
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LTB1S_HUMAN
NC score	0.354370 (rank : 188)	θ value	9.29e-05 (rank : 231)
Query Neighborhood Hits	600	Target Neighborhood Hits	502	Shared Neighborhood Hits	244
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.354000 (rank : 189)	θ value	9.29e-05 (rank : 230)
Query Neighborhood Hits	600	Target Neighborhood Hits	553	Shared Neighborhood Hits	256
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MYOM1_MOUSE
NC score	0.353484 (rank : 190)	θ value	0.00020696 (rank : 241)
Query Neighborhood Hits	600	Target Neighborhood Hits	415	Shared Neighborhood Hits	171
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

LRP1_HUMAN
NC score	0.351535 (rank : 191)	θ value	2.21117e-06 (rank : 193)
Query Neighborhood Hits	600	Target Neighborhood Hits	617	Shared Neighborhood Hits	278
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

PUNC_MOUSE
NC score	0.351405 (rank : 192)	θ value	1.80886e-08 (rank : 144)
Query Neighborhood Hits	600	Target Neighborhood Hits	501	Shared Neighborhood Hits	148
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

CUBN_HUMAN
NC score	0.350424 (rank : 193)	θ value	0.0330416 (rank : 334)
Query Neighborhood Hits	600	Target Neighborhood Hits	482	Shared Neighborhood Hits	232
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

SLIT2_MOUSE
NC score	0.349055 (rank : 194)	θ value	0.000158464 (rank : 238)
Query Neighborhood Hits	600	Target Neighborhood Hits	684	Shared Neighborhood Hits	231
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LTB1S_MOUSE
NC score	0.347328 (rank : 195)	θ value	4.1701e-05 (rank : 220)
Query Neighborhood Hits	600	Target Neighborhood Hits	479	Shared Neighborhood Hits	234
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.347168 (rank : 196)	θ value	4.1701e-05 (rank : 219)
Query Neighborhood Hits	600	Target Neighborhood Hits	514	Shared Neighborhood Hits	246
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

CUBN_MOUSE
NC score	0.346925 (rank : 197)	θ value	0.00228821 (rank : 277)
Query Neighborhood Hits	600	Target Neighborhood Hits	477	Shared Neighborhood Hits	233
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

SORL_HUMAN
NC score	0.345958 (rank : 198)	θ value	3.64472e-09 (rank : 130)
Query Neighborhood Hits	600	Target Neighborhood Hits	440	Shared Neighborhood Hits	288
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

EDIL3_MOUSE
NC score	0.345072 (rank : 199)	θ value	0.0193708 (rank : 316)
Query Neighborhood Hits	600	Target Neighborhood Hits	317	Shared Neighborhood Hits	191
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

HHIP_HUMAN
NC score	0.343111 (rank : 200)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	600	Target Neighborhood Hits	249	Shared Neighborhood Hits	175
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

SLIT3_MOUSE
NC score	0.342933 (rank : 201)	θ value	8.97725e-08 (rank : 159)
Query Neighborhood Hits	600	Target Neighborhood Hits	700	Shared Neighborhood Hits	243
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ROBO3_HUMAN
NC score	0.340704 (rank : 202)	θ value	1.53129e-07 (rank : 162)
Query Neighborhood Hits	600	Target Neighborhood Hits	570	Shared Neighborhood Hits	168
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

HMCN1_HUMAN
NC score	0.339841 (rank : 203)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	600	Target Neighborhood Hits	983	Shared Neighborhood Hits	299
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

SLIT3_HUMAN
NC score	0.339441 (rank : 204)	θ value	5.81887e-07 (rank : 178)
Query Neighborhood Hits	600	Target Neighborhood Hits	682	Shared Neighborhood Hits	235
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

ROBO3_MOUSE
NC score	0.336937 (rank : 205)	θ value	6.87365e-08 (rank : 153)
Query Neighborhood Hits	600	Target Neighborhood Hits	524	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

ROBO2_MOUSE
NC score	0.336639 (rank : 206)	θ value	2.21117e-06 (rank : 194)
Query Neighborhood Hits	600	Target Neighborhood Hits	504	Shared Neighborhood Hits	166
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

LRP1B_HUMAN
NC score	0.336520 (rank : 207)	θ value	1.87187e-05 (rank : 213)
Query Neighborhood Hits	600	Target Neighborhood Hits	602	Shared Neighborhood Hits	258
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

ROBO2_HUMAN
NC score	0.336484 (rank : 208)	θ value	3.19293e-05 (rank : 216)
Query Neighborhood Hits	600	Target Neighborhood Hits	479	Shared Neighborhood Hits	164
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

KR101_HUMAN
NC score	0.334494 (rank : 209)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	600	Target Neighborhood Hits	261	Shared Neighborhood Hits	147
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

IL6RB_HUMAN
NC score	0.334045 (rank : 210)	θ value	1.06045e-08 (rank : 140)
Query Neighborhood Hits	600	Target Neighborhood Hits	181	Shared Neighborhood Hits	128
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

LRP1B_MOUSE
NC score	0.333586 (rank : 211)	θ value	7.1131e-05 (rank : 226)
Query Neighborhood Hits	600	Target Neighborhood Hits	606	Shared Neighborhood Hits	261
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

NRX2A_HUMAN
NC score	0.333038 (rank : 212)	θ value	4.02038e-16 (rank : 75)
Query Neighborhood Hits	600	Target Neighborhood Hits	614	Shared Neighborhood Hits	132
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

ROBO1_MOUSE
NC score	0.331404 (rank : 213)	θ value	6.43352e-06 (rank : 205)
Query Neighborhood Hits	600	Target Neighborhood Hits	559	Shared Neighborhood Hits	168
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

COCA1_MOUSE
NC score	0.330428 (rank : 214)	θ value	6.21693e-09 (rank : 135)
Query Neighborhood Hits	600	Target Neighborhood Hits	467	Shared Neighborhood Hits	172
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

HHIP_MOUSE
NC score	0.330199 (rank : 215)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	600	Target Neighborhood Hits	219	Shared Neighborhood Hits	160
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

PROS_HUMAN
NC score	0.329799 (rank : 216)	θ value	0.00390308 (rank : 293)
Query Neighborhood Hits	600	Target Neighborhood Hits	340	Shared Neighborhood Hits	215
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

CDON_HUMAN
NC score	0.328240 (rank : 217)	θ value	4.92598e-06 (rank : 201)
Query Neighborhood Hits	600	Target Neighborhood Hits	412	Shared Neighborhood Hits	144
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

COMP_MOUSE
NC score	0.326456 (rank : 218)	θ value	1.06291 (rank : 421)
Query Neighborhood Hits	600	Target Neighborhood Hits	290	Shared Neighborhood Hits	202
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

GAS6_HUMAN
NC score	0.326220 (rank : 219)	θ value	0.0113563 (rank : 309)
Query Neighborhood Hits	600	Target Neighborhood Hits	348	Shared Neighborhood Hits	213
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

CDON_MOUSE
NC score	0.325260 (rank : 220)	θ value	1.69304e-06 (rank : 189)
Query Neighborhood Hits	600	Target Neighborhood Hits	410	Shared Neighborhood Hits	139
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

ROBO1_HUMAN
NC score	0.324141 (rank : 221)	θ value	7.1131e-05 (rank : 228)
Query Neighborhood Hits	600	Target Neighborhood Hits	529	Shared Neighborhood Hits	160
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

COCA1_HUMAN
NC score	0.323011 (rank : 222)	θ value	7.34386e-10 (rank : 118)
Query Neighborhood Hits	600	Target Neighborhood Hits	458	Shared Neighborhood Hits	164
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

GAS6_MOUSE
NC score	0.321630 (rank : 223)	θ value	2.36792 (rank : 465)
Query Neighborhood Hits	600	Target Neighborhood Hits	343	Shared Neighborhood Hits	217
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

PROS_MOUSE
NC score	0.320897 (rank : 224)	θ value	1.38821 (rank : 435)
Query Neighborhood Hits	600	Target Neighborhood Hits	330	Shared Neighborhood Hits	211
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

CELR2_HUMAN
NC score	0.320000 (rank : 225)	θ value	1.99529e-15 (rank : 78)
Query Neighborhood Hits	600	Target Neighborhood Hits	657	Shared Neighborhood Hits	247
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_HUMAN
NC score	0.318443 (rank : 226)	θ value	3.40345e-15 (rank : 80)
Query Neighborhood Hits	600	Target Neighborhood Hits	680	Shared Neighborhood Hits	247
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
NC score	0.317714 (rank : 227)	θ value	1.68911e-14 (rank : 85)
Query Neighborhood Hits	600	Target Neighborhood Hits	687	Shared Neighborhood Hits	250
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

BOC_HUMAN
NC score	0.316019 (rank : 228)	θ value	0.00175202 (rank : 270)
Query Neighborhood Hits	600	Target Neighborhood Hits	543	Shared Neighborhood Hits	150
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

EDIL3_HUMAN
NC score	0.315122 (rank : 229)	θ value	0.21417 (rank : 373)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	177
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

CELR1_HUMAN
NC score	0.310822 (rank : 230)	θ value	5.8054e-15 (rank : 82)
Query Neighborhood Hits	600	Target Neighborhood Hits	613	Shared Neighborhood Hits	231
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CNTP2_MOUSE
NC score	0.309953 (rank : 231)	θ value	1.29331e-14 (rank : 84)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	120
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

ITB8_HUMAN
NC score	0.309868 (rank : 232)	θ value	0.00228821 (rank : 280)
Query Neighborhood Hits	600	Target Neighborhood Hits	280	Shared Neighborhood Hits	194
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

CNTP2_HUMAN
NC score	0.309693 (rank : 233)	θ value	1.38178e-16 (rank : 73)
Query Neighborhood Hits	600	Target Neighborhood Hits	199	Shared Neighborhood Hits	121
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

BOC_MOUSE
NC score	0.309346 (rank : 234)	θ value	0.0330416 (rank : 333)
Query Neighborhood Hits	600	Target Neighborhood Hits	433	Shared Neighborhood Hits	138
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

FBLN2_HUMAN
NC score	0.308352 (rank : 235)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	600	Target Neighborhood Hits	392	Shared Neighborhood Hits	209
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

I12R2_MOUSE
NC score	0.308291 (rank : 236)	θ value	9.59137e-10 (rank : 120)
Query Neighborhood Hits	600	Target Neighborhood Hits	143	Shared Neighborhood Hits	112
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

CELR1_MOUSE
NC score	0.308176 (rank : 237)	θ value	9.26847e-13 (rank : 94)
Query Neighborhood Hits	600	Target Neighborhood Hits	617	Shared Neighborhood Hits	240
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

TSP4_MOUSE
NC score	0.307852 (rank : 238)	θ value	1.81305 (rank : 461)
Query Neighborhood Hits	600	Target Neighborhood Hits	276	Shared Neighborhood Hits	196
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

CNTP4_HUMAN
NC score	0.307694 (rank : 239)	θ value	1.74796e-11 (rank : 102)
Query Neighborhood Hits	600	Target Neighborhood Hits	187	Shared Neighborhood Hits	108
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

TSP4_HUMAN
NC score	0.306715 (rank : 240)	θ value	0.0252991 (rank : 332)
Query Neighborhood Hits	600	Target Neighborhood Hits	277	Shared Neighborhood Hits	186
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

I12R2_HUMAN
NC score	0.305630 (rank : 241)	θ value	2.21117e-06 (rank : 192)
Query Neighborhood Hits	600	Target Neighborhood Hits	163	Shared Neighborhood Hits	113
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

CELR2_MOUSE
NC score	0.305463 (rank : 242)	θ value	3.18553e-13 (rank : 92)
Query Neighborhood Hits	600	Target Neighborhood Hits	584	Shared Neighborhood Hits	226
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

NID2_HUMAN
NC score	0.304998 (rank : 243)	θ value	1.81305 (rank : 454)
Query Neighborhood Hits	600	Target Neighborhood Hits	456	Shared Neighborhood Hits	210
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LIFR_HUMAN
NC score	0.303067 (rank : 244)	θ value	8.97725e-08 (rank : 157)
Query Neighborhood Hits	600	Target Neighborhood Hits	130	Shared Neighborhood Hits	91
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

COMP_HUMAN
NC score	0.303051 (rank : 245)	θ value	3.0926 (rank : 474)
Query Neighborhood Hits	600	Target Neighborhood Hits	258	Shared Neighborhood Hits	180
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NID1_HUMAN
NC score	0.302585 (rank : 246)	θ value	0.0252991 (rank : 328)
Query Neighborhood Hits	600	Target Neighborhood Hits	329	Shared Neighborhood Hits	197
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

IL6RB_MOUSE
NC score	0.301328 (rank : 247)	θ value	5.44631e-05 (rank : 221)
Query Neighborhood Hits	600	Target Neighborhood Hits	168	Shared Neighborhood Hits	125
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

CNTP4_MOUSE
NC score	0.299693 (rank : 248)	θ value	4.45536e-07 (rank : 173)
Query Neighborhood Hits	600	Target Neighborhood Hits	193	Shared Neighborhood Hits	120
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

EGFL7_HUMAN
NC score	0.299072 (rank : 249)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	600	Target Neighborhood Hits	325	Shared Neighborhood Hits	190
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

FBLN2_MOUSE
NC score	0.298115 (rank : 250)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	600	Target Neighborhood Hits	505	Shared Neighborhood Hits	217
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LIFR_MOUSE
NC score	0.297480 (rank : 251)	θ value	4.92598e-06 (rank : 204)
Query Neighborhood Hits	600	Target Neighborhood Hits	127	Shared Neighborhood Hits	90
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

TSP3_MOUSE
NC score	0.297469 (rank : 252)	θ value	2.36792 (rank : 470)
Query Neighborhood Hits	600	Target Neighborhood Hits	247	Shared Neighborhood Hits	172
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

NID1_MOUSE
NC score	0.297380 (rank : 253)	θ value	0.0193708 (rank : 320)
Query Neighborhood Hits	600	Target Neighborhood Hits	335	Shared Neighborhood Hits	192
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NCAM2_MOUSE
NC score	0.296563 (rank : 254)	θ value	0.00175202 (rank : 275)
Query Neighborhood Hits	600	Target Neighborhood Hits	472	Shared Neighborhood Hits	152
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

UROM_HUMAN
NC score	0.295963 (rank : 255)	θ value	0.0113563 (rank : 312)
Query Neighborhood Hits	600	Target Neighborhood Hits	284	Shared Neighborhood Hits	181
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FBLN1_MOUSE
NC score	0.295486 (rank : 256)	θ value	0.00175202 (rank : 272)
Query Neighborhood Hits	600	Target Neighborhood Hits	329	Shared Neighborhood Hits	199
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

UROM_MOUSE
NC score	0.294158 (rank : 257)	θ value	2.44474e-05 (rank : 215)
Query Neighborhood Hits	600	Target Neighborhood Hits	276	Shared Neighborhood Hits	183
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

TIE1_HUMAN
NC score	0.292714 (rank : 258)	θ value	8.97725e-08 (rank : 160)
Query Neighborhood Hits	600	Target Neighborhood Hits	1241	Shared Neighborhood Hits	334
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
NC score	0.292299 (rank : 259)	θ value	8.11959e-09 (rank : 139)
Query Neighborhood Hits	600	Target Neighborhood Hits	1266	Shared Neighborhood Hits	334
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

KR102_HUMAN
NC score	0.291919 (rank : 260)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	600	Target Neighborhood Hits	264	Shared Neighborhood Hits	145
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

TRBM_HUMAN
NC score	0.290943 (rank : 261)	θ value	θ > 10 (rank : 1167)
Query Neighborhood Hits	600	Target Neighborhood Hits	339	Shared Neighborhood Hits	189
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP3_HUMAN
NC score	0.289911 (rank : 262)	θ value	0.365318 (rank : 394)
Query Neighborhood Hits	600	Target Neighborhood Hits	250	Shared Neighborhood Hits	165
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

NCAM2_HUMAN
NC score	0.287443 (rank : 263)	θ value	0.0736092 (rank : 352)
Query Neighborhood Hits	600	Target Neighborhood Hits	441	Shared Neighborhood Hits	148
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

COEA1_MOUSE
NC score	0.286852 (rank : 264)	θ value	8.97725e-08 (rank : 155)
Query Neighborhood Hits	600	Target Neighborhood Hits	402	Shared Neighborhood Hits	125
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

MATN2_HUMAN
NC score	0.286465 (rank : 265)	θ value	0.0431538 (rank : 342)
Query Neighborhood Hits	600	Target Neighborhood Hits	365	Shared Neighborhood Hits	200
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

KR108_HUMAN
NC score	0.285786 (rank : 266)	θ value	3.0926 (rank : 477)
Query Neighborhood Hits	600	Target Neighborhood Hits	226	Shared Neighborhood Hits	129
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

NPHN_HUMAN
NC score	0.284355 (rank : 267)	θ value	0.0252991 (rank : 329)
Query Neighborhood Hits	600	Target Neighborhood Hits	362	Shared Neighborhood Hits	122
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

CNTP1_MOUSE
NC score	0.283910 (rank : 268)	θ value	1.47974e-10 (rank : 109)
Query Neighborhood Hits	600	Target Neighborhood Hits	183	Shared Neighborhood Hits	100
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

NID2_MOUSE
NC score	0.283754 (rank : 269)	θ value	θ > 10 (rank : 979)
Query Neighborhood Hits	600	Target Neighborhood Hits	338	Shared Neighborhood Hits	198
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

CNTP1_HUMAN
NC score	0.283698 (rank : 270)	θ value	4.30538e-10 (rank : 113)
Query Neighborhood Hits	600	Target Neighborhood Hits	196	Shared Neighborhood Hits	103
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

C1QR1_HUMAN
NC score	0.283206 (rank : 271)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	600	Target Neighborhood Hits	493	Shared Neighborhood Hits	213
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

FBLN1_HUMAN
NC score	0.283111 (rank : 272)	θ value	0.00298849 (rank : 285)
Query Neighborhood Hits	600	Target Neighborhood Hits	324	Shared Neighborhood Hits	202
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

EGFL7_MOUSE
NC score	0.282939 (rank : 273)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	600	Target Neighborhood Hits	287	Shared Neighborhood Hits	172
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

TRBM_MOUSE
NC score	0.281321 (rank : 274)	θ value	θ > 10 (rank : 1168)
Query Neighborhood Hits	600	Target Neighborhood Hits	361	Shared Neighborhood Hits	202
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CNTP3_HUMAN
NC score	0.280590 (rank : 275)	θ value	1.87187e-05 (rank : 211)
Query Neighborhood Hits	600	Target Neighborhood Hits	195	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

LRP2_HUMAN
NC score	0.280342 (rank : 276)	θ value	0.163984 (rank : 368)
Query Neighborhood Hits	600	Target Neighborhood Hits	573	Shared Neighborhood Hits	262
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

C1QR1_MOUSE
NC score	0.279840 (rank : 277)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	600	Target Neighborhood Hits	342	Shared Neighborhood Hits	195
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

TIE2_MOUSE
NC score	0.278904 (rank : 278)	θ value	6.21693e-09 (rank : 137)
Query Neighborhood Hits	600	Target Neighborhood Hits	1204	Shared Neighborhood Hits	339
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

EGF_MOUSE
NC score	0.277343 (rank : 279)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	600	Target Neighborhood Hits	358	Shared Neighborhood Hits	202
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

MT3_MOUSE
NC score	0.276818 (rank : 280)	θ value	1.81305 (rank : 449)
Query Neighborhood Hits	600	Target Neighborhood Hits	68	Shared Neighborhood Hits	49
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

KR10C_HUMAN
NC score	0.276528 (rank : 281)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	600	Target Neighborhood Hits	219	Shared Neighborhood Hits	128
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR109_HUMAN
NC score	0.276236 (rank : 282)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	600	Target Neighborhood Hits	226	Shared Neighborhood Hits	130
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR105_HUMAN
NC score	0.276064 (rank : 283)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	600	Target Neighborhood Hits	271	Shared Neighborhood Hits	148
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

TIE2_HUMAN
NC score	0.274926 (rank : 284)	θ value	1.25267e-09 (rank : 121)
Query Neighborhood Hits	600	Target Neighborhood Hits	1192	Shared Neighborhood Hits	327
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

ROBO4_HUMAN
NC score	0.274475 (rank : 285)	θ value	1.81305 (rank : 458)
Query Neighborhood Hits	600	Target Neighborhood Hits	364	Shared Neighborhood Hits	111
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

CSF3R_HUMAN
NC score	0.273410 (rank : 286)	θ value	3.77169e-06 (rank : 197)
Query Neighborhood Hits	600	Target Neighborhood Hits	140	Shared Neighborhood Hits	103
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

MYPC2_MOUSE
NC score	0.273156 (rank : 287)	θ value	0.279714 (rank : 382)
Query Neighborhood Hits	600	Target Neighborhood Hits	297	Shared Neighborhood Hits	122
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NPHN_MOUSE
NC score	0.273018 (rank : 288)	θ value	0.0431538 (rank : 343)
Query Neighborhood Hits	600	Target Neighborhood Hits	370	Shared Neighborhood Hits	126
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

PTPRM_HUMAN
NC score	0.272911 (rank : 289)	θ value	4.0297e-08 (rank : 149)
Query Neighborhood Hits	600	Target Neighborhood Hits	244	Shared Neighborhood Hits	143
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

KR10B_HUMAN
NC score	0.272833 (rank : 290)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	600	Target Neighborhood Hits	269	Shared Neighborhood Hits	140
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

MYPC3_HUMAN
NC score	0.272490 (rank : 291)	θ value	0.0563607 (rank : 346)
Query Neighborhood Hits	600	Target Neighborhood Hits	318	Shared Neighborhood Hits	136
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

PTPRM_MOUSE
NC score	0.272285 (rank : 292)	θ value	4.0297e-08 (rank : 150)
Query Neighborhood Hits	600	Target Neighborhood Hits	238	Shared Neighborhood Hits	143
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

NCA11_HUMAN
NC score	0.271443 (rank : 293)	θ value	0.0330416 (rank : 337)
Query Neighborhood Hits	600	Target Neighborhood Hits	443	Shared Neighborhood Hits	132
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

MYPC3_MOUSE
NC score	0.271075 (rank : 294)	θ value	0.0736092 (rank : 351)
Query Neighborhood Hits	600	Target Neighborhood Hits	310	Shared Neighborhood Hits	137
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NCA11_MOUSE
NC score	0.270229 (rank : 295)	θ value	0.00509761 (rank : 298)
Query Neighborhood Hits	600	Target Neighborhood Hits	661	Shared Neighborhood Hits	141
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

ROBO4_MOUSE
NC score	0.270126 (rank : 296)	θ value	3.0926 (rank : 483)
Query Neighborhood Hits	600	Target Neighborhood Hits	358	Shared Neighborhood Hits	109
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

MATN2_MOUSE
NC score	0.269323 (rank : 297)	θ value	θ > 10 (rank : 939)
Query Neighborhood Hits	600	Target Neighborhood Hits	356	Shared Neighborhood Hits	191
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MYPC2_HUMAN
NC score	0.266899 (rank : 298)	θ value	1.81305 (rank : 453)
Query Neighborhood Hits	600	Target Neighborhood Hits	316	Shared Neighborhood Hits	130
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NCA12_MOUSE
NC score	0.266295 (rank : 299)	θ value	0.000786445 (rank : 259)
Query Neighborhood Hits	600	Target Neighborhood Hits	399	Shared Neighborhood Hits	117
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

FBLN5_HUMAN
NC score	0.263104 (rank : 300)	θ value	8.99809 (rank : 583)
Query Neighborhood Hits	600	Target Neighborhood Hits	329	Shared Neighborhood Hits	201
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

PTPRT_MOUSE
NC score	0.262365 (rank : 301)	θ value	2.79066e-09 (rank : 129)
Query Neighborhood Hits	600	Target Neighborhood Hits	219	Shared Neighborhood Hits	134
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.261961 (rank : 302)	θ value	2.79066e-09 (rank : 128)
Query Neighborhood Hits	600	Target Neighborhood Hits	217	Shared Neighborhood Hits	133
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

KRA47_HUMAN
NC score	0.261684 (rank : 303)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	600	Target Neighborhood Hits	204	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

NCA12_HUMAN
NC score	0.261259 (rank : 304)	θ value	0.0961366 (rank : 357)
Query Neighborhood Hits	600	Target Neighborhood Hits	437	Shared Neighborhood Hits	126
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

MYPC1_HUMAN
NC score	0.261099 (rank : 305)	θ value	0.00509761 (rank : 297)
Query Neighborhood Hits	600	Target Neighborhood Hits	303	Shared Neighborhood Hits	121
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

FBLN5_MOUSE
NC score	0.260034 (rank : 306)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	600	Target Neighborhood Hits	317	Shared Neighborhood Hits	196
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

COEA1_HUMAN
NC score	0.259760 (rank : 307)	θ value	1.69304e-06 (rank : 191)
Query Neighborhood Hits	600	Target Neighborhood Hits	427	Shared Neighborhood Hits	139
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

FBLN4_HUMAN
NC score	0.258888 (rank : 308)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	600	Target Neighborhood Hits	278	Shared Neighborhood Hits	175
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FATH_HUMAN
NC score	0.258394 (rank : 309)	θ value	4.1701e-05 (rank : 218)
Query Neighborhood Hits	600	Target Neighborhood Hits	570	Shared Neighborhood Hits	233
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

SUSD1_HUMAN
NC score	0.258275 (rank : 310)	θ value	θ > 10 (rank : 1131)
Query Neighborhood Hits	600	Target Neighborhood Hits	285	Shared Neighborhood Hits	166
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

PTPRU_HUMAN
NC score	0.256619 (rank : 311)	θ value	8.97725e-08 (rank : 158)
Query Neighborhood Hits	600	Target Neighborhood Hits	237	Shared Neighborhood Hits	142
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

MFGM_MOUSE
NC score	0.253389 (rank : 312)	θ value	θ > 10 (rank : 953)
Query Neighborhood Hits	600	Target Neighborhood Hits	233	Shared Neighborhood Hits	150
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

SSPO_MOUSE
NC score	0.252178 (rank : 313)	θ value	0.00390308 (rank : 294)
Query Neighborhood Hits	600	Target Neighborhood Hits	800	Shared Neighborhood Hits	282
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

FBLN4_MOUSE
NC score	0.251840 (rank : 314)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	600	Target Neighborhood Hits	270	Shared Neighborhood Hits	170
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

CSPG3_MOUSE
NC score	0.251782 (rank : 315)	θ value	0.47712 (rank : 396)
Query Neighborhood Hits	600	Target Neighborhood Hits	657	Shared Neighborhood Hits	206
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

HCFC2_MOUSE
NC score	0.251636 (rank : 316)	θ value	0.00175202 (rank : 273)
Query Neighborhood Hits	600	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

KRA11_HUMAN
NC score	0.250929 (rank : 317)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	600	Target Neighborhood Hits	155	Shared Neighborhood Hits	86
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

COKA1_HUMAN
NC score	0.249619 (rank : 318)	θ value	0.000270298 (rank : 242)
Query Neighborhood Hits	600	Target Neighborhood Hits	403	Shared Neighborhood Hits	129
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

OBSL1_HUMAN
NC score	0.249464 (rank : 319)	θ value	θ > 10 (rank : 996)
Query Neighborhood Hits	600	Target Neighborhood Hits	354	Shared Neighborhood Hits	87
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

EGFL8_HUMAN
NC score	0.249373 (rank : 320)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	600	Target Neighborhood Hits	270	Shared Neighborhood Hits	150
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGF_HUMAN
NC score	0.248863 (rank : 321)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	600	Target Neighborhood Hits	343	Shared Neighborhood Hits	193
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EMR1_HUMAN
NC score	0.248018 (rank : 322)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	600	Target Neighborhood Hits	382	Shared Neighborhood Hits	192
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

CSPG3_HUMAN
NC score	0.246533 (rank : 323)	θ value	1.81305 (rank : 442)
Query Neighborhood Hits	600	Target Neighborhood Hits	676	Shared Neighborhood Hits	208
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CO7A1_HUMAN
NC score	0.246143 (rank : 324)	θ value	1.33837e-11 (rank : 101)
Query Neighborhood Hits	600	Target Neighborhood Hits	807	Shared Neighborhood Hits	173
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

FBLN3_HUMAN
NC score	0.246140 (rank : 325)	θ value	6.88961 (rank : 548)
Query Neighborhood Hits	600	Target Neighborhood Hits	293	Shared Neighborhood Hits	183
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

LRP8_MOUSE
NC score	0.246123 (rank : 326)	θ value	7.1131e-05 (rank : 227)
Query Neighborhood Hits	600	Target Neighborhood Hits	385	Shared Neighborhood Hits	193
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

EGFL8_MOUSE
NC score	0.245714 (rank : 327)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	600	Target Neighborhood Hits	266	Shared Neighborhood Hits	153
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

VLDLR_MOUSE
NC score	0.244573 (rank : 328)	θ value	0.0330416 (rank : 339)
Query Neighborhood Hits	600	Target Neighborhood Hits	360	Shared Neighborhood Hits	193
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LDLR_HUMAN
NC score	0.243563 (rank : 329)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	600	Target Neighborhood Hits	375	Shared Neighborhood Hits	202
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

PTPRK_MOUSE
NC score	0.243291 (rank : 330)	θ value	4.76016e-09 (rank : 133)
Query Neighborhood Hits	600	Target Neighborhood Hits	223	Shared Neighborhood Hits	128
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

VLDLR_HUMAN
NC score	0.243103 (rank : 331)	θ value	θ > 10 (rank : 1195)
Query Neighborhood Hits	600	Target Neighborhood Hits	383	Shared Neighborhood Hits	200
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

GRN_MOUSE
NC score	0.242691 (rank : 332)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	600	Target Neighborhood Hits	248	Shared Neighborhood Hits	144
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

MDGA1_HUMAN
NC score	0.240992 (rank : 333)	θ value	1.81305 (rank : 447)
Query Neighborhood Hits	600	Target Neighborhood Hits	358	Shared Neighborhood Hits	94
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

PTPRK_HUMAN
NC score	0.240741 (rank : 334)	θ value	1.06045e-08 (rank : 141)
Query Neighborhood Hits	600	Target Neighborhood Hits	228	Shared Neighborhood Hits	129
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

TNR4_MOUSE
NC score	0.237853 (rank : 335)	θ value	0.00298849 (rank : 288)
Query Neighborhood Hits	600	Target Neighborhood Hits	137	Shared Neighborhood Hits	89
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

GRN_HUMAN
NC score	0.237496 (rank : 336)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	600	Target Neighborhood Hits	268	Shared Neighborhood Hits	148
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

MAMC1_MOUSE
NC score	0.236845 (rank : 337)	θ value	θ > 10 (rank : 934)
Query Neighborhood Hits	600	Target Neighborhood Hits	357	Shared Neighborhood Hits	92
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

KRA45_HUMAN
NC score	0.236805 (rank : 338)	θ value	8.99809 (rank : 586)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

ESM1_HUMAN
NC score	0.235961 (rank : 339)	θ value	2.36792 (rank : 464)
Query Neighborhood Hits	600	Target Neighborhood Hits	110	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

EMR2_HUMAN
NC score	0.235649 (rank : 340)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	600	Target Neighborhood Hits	345	Shared Neighborhood Hits	175
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

MAMC1_HUMAN
NC score	0.235635 (rank : 341)	θ value	θ > 10 (rank : 933)
Query Neighborhood Hits	600	Target Neighborhood Hits	357	Shared Neighborhood Hits	92
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

KRA93_HUMAN
NC score	0.235139 (rank : 342)	θ value	4.03905 (rank : 497)
Query Neighborhood Hits	600	Target Neighborhood Hits	203	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

CSPG2_HUMAN
NC score	0.234027 (rank : 343)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	600	Target Neighborhood Hits	681	Shared Neighborhood Hits	205
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

PCSK5_HUMAN
NC score	0.233700 (rank : 344)	θ value	0.000786445 (rank : 260)
Query Neighborhood Hits	600	Target Neighborhood Hits	291	Shared Neighborhood Hits	184
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

KR414_HUMAN
NC score	0.233210 (rank : 345)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	600	Target Neighborhood Hits	199	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

CD97_HUMAN
NC score	0.233129 (rank : 346)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	600	Target Neighborhood Hits	353	Shared Neighborhood Hits	174
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

KRA94_HUMAN
NC score	0.233073 (rank : 347)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	600	Target Neighborhood Hits	204	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

TITIN_HUMAN
NC score	0.232701 (rank : 348)	θ value	2.27234e-27 (rank : 44)
Query Neighborhood Hits	600	Target Neighborhood Hits	2923	Shared Neighborhood Hits	236
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CSPG2_MOUSE
NC score	0.232611 (rank : 349)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	600	Target Neighborhood Hits	711	Shared Neighborhood Hits	201
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

LCE1C_HUMAN
NC score	0.232469 (rank : 350)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	600	Target Neighborhood Hits	65	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

PTPRB_HUMAN
NC score	0.232067 (rank : 351)	θ value	5.26297e-08 (rank : 151)
Query Neighborhood Hits	600	Target Neighborhood Hits	242	Shared Neighborhood Hits	110
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

LDLR_MOUSE
NC score	0.232035 (rank : 352)	θ value	0.279714 (rank : 381)
Query Neighborhood Hits	600	Target Neighborhood Hits	382	Shared Neighborhood Hits	196
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

FGRL1_HUMAN
NC score	0.230589 (rank : 353)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	600	Target Neighborhood Hits	335	Shared Neighborhood Hits	87
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

MYPN_HUMAN
NC score	0.229749 (rank : 354)	θ value	θ > 10 (rank : 972)
Query Neighborhood Hits	600	Target Neighborhood Hits	418	Shared Neighborhood Hits	92
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

FBLN3_MOUSE
NC score	0.229707 (rank : 355)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	600	Target Neighborhood Hits	279	Shared Neighborhood Hits	166
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FGRL1_MOUSE
NC score	0.229161 (rank : 356)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	600	Target Neighborhood Hits	325	Shared Neighborhood Hits	87
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

MYOTI_MOUSE
NC score	0.229127 (rank : 357)	θ value	θ > 10 (rank : 971)
Query Neighborhood Hits	600	Target Neighborhood Hits	297	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYOTI_HUMAN
NC score	0.227500 (rank : 358)	θ value	θ > 10 (rank : 970)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

TNR16_HUMAN
NC score	0.225725 (rank : 359)	θ value	0.0961366 (rank : 360)
Query Neighborhood Hits	600	Target Neighborhood Hits	183	Shared Neighborhood Hits	118
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

MYPN_MOUSE
NC score	0.225679 (rank : 360)	θ value	θ > 10 (rank : 973)
Query Neighborhood Hits	600	Target Neighborhood Hits	421	Shared Neighborhood Hits	93
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

KRA13_HUMAN
NC score	0.225618 (rank : 361)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	600	Target Neighborhood Hits	144	Shared Neighborhood Hits	82
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KR10A_HUMAN
NC score	0.223669 (rank : 362)	θ value	0.00390308 (rank : 290)
Query Neighborhood Hits	600	Target Neighborhood Hits	232	Shared Neighborhood Hits	129
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

TSP1_MOUSE
NC score	0.222980 (rank : 363)	θ value	0.365318 (rank : 393)
Query Neighborhood Hits	600	Target Neighborhood Hits	396	Shared Neighborhood Hits	199
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

NRG2_MOUSE
NC score	0.222959 (rank : 364)	θ value	θ > 10 (rank : 984)
Query Neighborhood Hits	600	Target Neighborhood Hits	392	Shared Neighborhood Hits	162
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

KRA92_HUMAN
NC score	0.222580 (rank : 365)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	600	Target Neighborhood Hits	198	Shared Neighborhood Hits	111
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA98_HUMAN
NC score	0.221645 (rank : 366)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	600	Target Neighborhood Hits	185	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

EMR1_MOUSE
NC score	0.219652 (rank : 367)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	600	Target Neighborhood Hits	349	Shared Neighborhood Hits	163
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

CSF3R_MOUSE
NC score	0.219512 (rank : 368)	θ value	0.00509761 (rank : 295)
Query Neighborhood Hits	600	Target Neighborhood Hits	104	Shared Neighborhood Hits	79
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

TSP1_HUMAN
NC score	0.219064 (rank : 369)	θ value	0.813845 (rank : 419)
Query Neighborhood Hits	600	Target Neighborhood Hits	389	Shared Neighborhood Hits	199
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

KALM_HUMAN
NC score	0.218455 (rank : 370)	θ value	0.813845 (rank : 414)
Query Neighborhood Hits	600	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

LRP8_HUMAN
NC score	0.217468 (rank : 371)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	600	Target Neighborhood Hits	346	Shared Neighborhood Hits	176
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MATN3_MOUSE
NC score	0.217460 (rank : 372)	θ value	0.0330416 (rank : 335)
Query Neighborhood Hits	600	Target Neighborhood Hits	261	Shared Neighborhood Hits	148
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

KRA44_HUMAN
NC score	0.216698 (rank : 373)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	600	Target Neighborhood Hits	162	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

CD248_HUMAN
NC score	0.216315 (rank : 374)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	600	Target Neighborhood Hits	679	Shared Neighborhood Hits	175
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TNR4_HUMAN
NC score	0.213884 (rank : 375)	θ value	0.365318 (rank : 391)
Query Neighborhood Hits	600	Target Neighborhood Hits	152	Shared Neighborhood Hits	90
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

LRP4_MOUSE
NC score	0.213086 (rank : 376)	θ value	3.0926 (rank : 479)
Query Neighborhood Hits	600	Target Neighborhood Hits	351	Shared Neighborhood Hits	182
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

NFX1_HUMAN
NC score	0.212836 (rank : 377)	θ value	3.0926 (rank : 481)
Query Neighborhood Hits	600	Target Neighborhood Hits	405	Shared Neighborhood Hits	140
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

LRP4_HUMAN
NC score	0.212830 (rank : 378)	θ value	0.365318 (rank : 389)
Query Neighborhood Hits	600	Target Neighborhood Hits	355	Shared Neighborhood Hits	180
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

MATN4_HUMAN
NC score	0.212785 (rank : 379)	θ value	θ > 10 (rank : 941)
Query Neighborhood Hits	600	Target Neighborhood Hits	287	Shared Neighborhood Hits	161
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MUC5B_HUMAN
NC score	0.212326 (rank : 380)	θ value	4.03905 (rank : 502)
Query Neighborhood Hits	600	Target Neighborhood Hits	1020	Shared Neighborhood Hits	249
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TNR25_HUMAN
NC score	0.211670 (rank : 381)	θ value	0.0330416 (rank : 338)
Query Neighborhood Hits	600	Target Neighborhood Hits	172	Shared Neighborhood Hits	100
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

LCE1B_HUMAN
NC score	0.211040 (rank : 382)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	600	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

MYBPH_MOUSE
NC score	0.210345 (rank : 383)	θ value	θ > 10 (rank : 969)
Query Neighborhood Hits	600	Target Neighborhood Hits	290	Shared Neighborhood Hits	117
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MATN4_MOUSE
NC score	0.209332 (rank : 384)	θ value	1.06291 (rank : 425)
Query Neighborhood Hits	600	Target Neighborhood Hits	277	Shared Neighborhood Hits	150
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

TNR16_MOUSE
NC score	0.208967 (rank : 385)	θ value	0.125558 (rank : 366)
Query Neighborhood Hits	600	Target Neighborhood Hits	178	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

ESM1_MOUSE
NC score	0.208881 (rank : 386)	θ value	1.81305 (rank : 443)
Query Neighborhood Hits	600	Target Neighborhood Hits	107	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

PROZ_MOUSE
NC score	0.208742 (rank : 387)	θ value	θ > 10 (rank : 1029)
Query Neighborhood Hits	600	Target Neighborhood Hits	410	Shared Neighborhood Hits	166
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

KR103_HUMAN
NC score	0.208715 (rank : 388)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	600	Target Neighborhood Hits	212	Shared Neighborhood Hits	117
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

CD248_MOUSE
NC score	0.208569 (rank : 389)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	600	Target Neighborhood Hits	578	Shared Neighborhood Hits	159
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MATN3_HUMAN
NC score	0.208566 (rank : 390)	θ value	θ > 10 (rank : 940)
Query Neighborhood Hits	600	Target Neighborhood Hits	268	Shared Neighborhood Hits	146
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

PCSK6_HUMAN
NC score	0.208561 (rank : 391)	θ value	0.0193708 (rank : 321)
Query Neighborhood Hits	600	Target Neighborhood Hits	298	Shared Neighborhood Hits	154
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

TNR23_MOUSE
NC score	0.205926 (rank : 392)	θ value	0.00509761 (rank : 299)
Query Neighborhood Hits	600	Target Neighborhood Hits	114	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

NRG2_HUMAN
NC score	0.205901 (rank : 393)	θ value	θ > 10 (rank : 983)
Query Neighborhood Hits	600	Target Neighborhood Hits	419	Shared Neighborhood Hits	149
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

PTPRV_MOUSE
NC score	0.204858 (rank : 394)	θ value	1.99992e-07 (rank : 164)
Query Neighborhood Hits	600	Target Neighborhood Hits	179	Shared Neighborhood Hits	84
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

LYAM2_MOUSE
NC score	0.204649 (rank : 395)	θ value	1.81305 (rank : 445)
Query Neighborhood Hits	600	Target Neighborhood Hits	420	Shared Neighborhood Hits	195
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

VWF_HUMAN
NC score	0.204193 (rank : 396)	θ value	0.62314 (rank : 407)
Query Neighborhood Hits	600	Target Neighborhood Hits	396	Shared Neighborhood Hits	194
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CFC1_HUMAN
NC score	0.202015 (rank : 397)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	600	Target Neighborhood Hits	148	Shared Neighborhood Hits	111
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

PROZ_HUMAN
NC score	0.201210 (rank : 398)	θ value	θ > 10 (rank : 1028)
Query Neighborhood Hits	600	Target Neighborhood Hits	422	Shared Neighborhood Hits	175
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

MYBPH_HUMAN
NC score	0.201065 (rank : 399)	θ value	4.03905 (rank : 503)
Query Neighborhood Hits	600	Target Neighborhood Hits	256	Shared Neighborhood Hits	109
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

MALT1_HUMAN
NC score	0.200767 (rank : 400)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

LSAMP_MOUSE
NC score	0.200473 (rank : 401)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	600	Target Neighborhood Hits	344	Shared Neighborhood Hits	84
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

KAZD1_HUMAN
NC score	0.200347 (rank : 402)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	600	Target Neighborhood Hits	248	Shared Neighborhood Hits	97
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

NEGR1_HUMAN
NC score	0.200168 (rank : 403)	θ value	θ > 10 (rank : 974)
Query Neighborhood Hits	600	Target Neighborhood Hits	346	Shared Neighborhood Hits	83
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

KR412_HUMAN
NC score	0.199763 (rank : 404)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	600	Target Neighborhood Hits	178	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

ZAN_HUMAN
NC score	0.199473 (rank : 405)	θ value	0.62314 (rank : 408)
Query Neighborhood Hits	600	Target Neighborhood Hits	679	Shared Neighborhood Hits	227
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

MKS3_MOUSE
NC score	0.199451 (rank : 406)	θ value	0.00665767 (rank : 303)
Query Neighborhood Hits	600	Target Neighborhood Hits	89	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

NEGR1_MOUSE
NC score	0.198822 (rank : 407)	θ value	θ > 10 (rank : 975)
Query Neighborhood Hits	600	Target Neighborhood Hits	349	Shared Neighborhood Hits	83
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

LSAMP_HUMAN
NC score	0.198547 (rank : 408)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	600	Target Neighborhood Hits	347	Shared Neighborhood Hits	84
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

OPCM_HUMAN
NC score	0.198228 (rank : 409)	θ value	θ > 10 (rank : 998)
Query Neighborhood Hits	600	Target Neighborhood Hits	332	Shared Neighborhood Hits	86
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

KAZD1_MOUSE
NC score	0.197336 (rank : 410)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	600	Target Neighborhood Hits	281	Shared Neighborhood Hits	94
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

MT3_HUMAN
NC score	0.197017 (rank : 411)	θ value	θ > 10 (rank : 961)
Query Neighborhood Hits	600	Target Neighborhood Hits	82	Shared Neighborhood Hits	52
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

VCAM1_MOUSE
NC score	0.193284 (rank : 412)	θ value	θ > 10 (rank : 1187)
Query Neighborhood Hits	600	Target Neighborhood Hits	320	Shared Neighborhood Hits	80
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

ELTD1_MOUSE
NC score	0.193212 (rank : 413)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	600	Target Neighborhood Hits	288	Shared Neighborhood Hits	145
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

TNR9_MOUSE
NC score	0.192575 (rank : 414)	θ value	9.29e-05 (rank : 233)
Query Neighborhood Hits	600	Target Neighborhood Hits	137	Shared Neighborhood Hits	88
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TSP2_MOUSE
NC score	0.192439 (rank : 415)	θ value	0.00134147 (rank : 268)
Query Neighborhood Hits	600	Target Neighborhood Hits	352	Shared Neighborhood Hits	177
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ICAM5_MOUSE
NC score	0.191192 (rank : 416)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	600	Target Neighborhood Hits	308	Shared Neighborhood Hits	83
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

PTPRJ_MOUSE
NC score	0.191182 (rank : 417)	θ value	9.29e-05 (rank : 232)
Query Neighborhood Hits	600	Target Neighborhood Hits	188	Shared Neighborhood Hits	100
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

NTRI_MOUSE
NC score	0.190985 (rank : 418)	θ value	θ > 10 (rank : 991)
Query Neighborhood Hits	600	Target Neighborhood Hits	342	Shared Neighborhood Hits	85
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

SN_MOUSE
NC score	0.190916 (rank : 419)	θ value	6.88961 (rank : 559)
Query Neighborhood Hits	600	Target Neighborhood Hits	416	Shared Neighborhood Hits	90
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

KIRR2_HUMAN
NC score	0.190357 (rank : 420)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	600	Target Neighborhood Hits	321	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

VCAM1_HUMAN
NC score	0.190146 (rank : 421)	θ value	θ > 10 (rank : 1186)
Query Neighborhood Hits	600	Target Neighborhood Hits	352	Shared Neighborhood Hits	82
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

KRA15_HUMAN
NC score	0.189551 (rank : 422)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	600	Target Neighborhood Hits	126	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

NTRI_HUMAN
NC score	0.189229 (rank : 423)	θ value	θ > 10 (rank : 990)
Query Neighborhood Hits	600	Target Neighborhood Hits	344	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

TDGF1_MOUSE
NC score	0.189050 (rank : 424)	θ value	θ > 10 (rank : 1133)
Query Neighborhood Hits	600	Target Neighborhood Hits	146	Shared Neighborhood Hits	107
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

FSTL4_MOUSE
NC score	0.188472 (rank : 425)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	600	Target Neighborhood Hits	333	Shared Neighborhood Hits	92
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

LYAM3_MOUSE
NC score	0.188163 (rank : 426)	θ value	1.81305 (rank : 446)
Query Neighborhood Hits	600	Target Neighborhood Hits	390	Shared Neighborhood Hits	169
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MUC18_HUMAN
NC score	0.187763 (rank : 427)	θ value	8.99809 (rank : 588)
Query Neighborhood Hits	600	Target Neighborhood Hits	275	Shared Neighborhood Hits	81
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

KIRR2_MOUSE
NC score	0.187387 (rank : 428)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	600	Target Neighborhood Hits	326	Shared Neighborhood Hits	83
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

PTPRJ_HUMAN
NC score	0.187248 (rank : 429)	θ value	0.0252991 (rank : 330)
Query Neighborhood Hits	600	Target Neighborhood Hits	207	Shared Neighborhood Hits	103
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

TARSH_HUMAN
NC score	0.186949 (rank : 430)	θ value	0.0148317 (rank : 314)
Query Neighborhood Hits	600	Target Neighborhood Hits	768	Shared Neighborhood Hits	131
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

SHBG_HUMAN
NC score	0.186825 (rank : 431)	θ value	3.0926 (rank : 484)
Query Neighborhood Hits	600	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

FSTL5_HUMAN
NC score	0.186708 (rank : 432)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	600	Target Neighborhood Hits	347	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

ICAM5_HUMAN
NC score	0.186309 (rank : 433)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	600	Target Neighborhood Hits	276	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

NPTN_HUMAN
NC score	0.185986 (rank : 434)	θ value	θ > 10 (rank : 980)
Query Neighborhood Hits	600	Target Neighborhood Hits	212	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

FSTL4_HUMAN
NC score	0.185963 (rank : 435)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	600	Target Neighborhood Hits	344	Shared Neighborhood Hits	93
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

LU_HUMAN
NC score	0.185860 (rank : 436)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	600	Target Neighborhood Hits	283	Shared Neighborhood Hits	84
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

EPHB6_HUMAN
NC score	0.185286 (rank : 437)	θ value	0.00134147 (rank : 266)
Query Neighborhood Hits	600	Target Neighborhood Hits	912	Shared Neighborhood Hits	200
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

LYAM2_HUMAN
NC score	0.184612 (rank : 438)	θ value	0.125558 (rank : 364)
Query Neighborhood Hits	600	Target Neighborhood Hits	394	Shared Neighborhood Hits	181
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

HCFC2_HUMAN
NC score	0.184547 (rank : 439)	θ value	0.00228821 (rank : 279)
Query Neighborhood Hits	600	Target Neighborhood Hits	154	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

FSTL5_MOUSE
NC score	0.184423 (rank : 440)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	600	Target Neighborhood Hits	355	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

MAG_HUMAN
NC score	0.184255 (rank : 441)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	600	Target Neighborhood Hits	278	Shared Neighborhood Hits	82
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
NC score	0.184120 (rank : 442)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	600	Target Neighborhood Hits	271	Shared Neighborhood Hits	82
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

TMIGD_MOUSE
NC score	0.184046 (rank : 443)	θ value	θ > 10 (rank : 1147)
Query Neighborhood Hits	600	Target Neighborhood Hits	234	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

RAGE_HUMAN
NC score	0.184019 (rank : 444)	θ value	θ > 10 (rank : 1089)
Query Neighborhood Hits	600	Target Neighborhood Hits	269	Shared Neighborhood Hits	83
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

TMIGD_HUMAN
NC score	0.183939 (rank : 445)	θ value	θ > 10 (rank : 1146)
Query Neighborhood Hits	600	Target Neighborhood Hits	240	Shared Neighborhood Hits	83
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

SN_HUMAN
NC score	0.183055 (rank : 446)	θ value	θ > 10 (rank : 1119)
Query Neighborhood Hits	600	Target Neighborhood Hits	434	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

TSP2_HUMAN
NC score	0.182263 (rank : 447)	θ value	0.0193708 (rank : 323)
Query Neighborhood Hits	600	Target Neighborhood Hits	359	Shared Neighborhood Hits	175
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

NRG1_HUMAN
NC score	0.182206 (rank : 448)	θ value	θ > 10 (rank : 982)
Query Neighborhood Hits	600	Target Neighborhood Hits	285	Shared Neighborhood Hits	133
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

KRA99_HUMAN
NC score	0.181800 (rank : 449)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	600	Target Neighborhood Hits	173	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

HABP2_HUMAN
NC score	0.181774 (rank : 450)	θ value	0.365318 (rank : 388)
Query Neighborhood Hits	600	Target Neighborhood Hits	431	Shared Neighborhood Hits	186
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

CFC1_MOUSE
NC score	0.181109 (rank : 451)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	600	Target Neighborhood Hits	125	Shared Neighborhood Hits	96
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CI094_HUMAN
NC score	0.180382 (rank : 452)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	600	Target Neighborhood Hits	310	Shared Neighborhood Hits	92
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CD97_MOUSE
NC score	0.179019 (rank : 453)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	600	Target Neighborhood Hits	295	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

PTK7_HUMAN
NC score	0.178864 (rank : 454)	θ value	θ > 10 (rank : 1042)
Query Neighborhood Hits	600	Target Neighborhood Hits	1103	Shared Neighborhood Hits	126
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

EPHA7_HUMAN
NC score	0.178639 (rank : 455)	θ value	4.0297e-08 (rank : 148)
Query Neighborhood Hits	600	Target Neighborhood Hits	1053	Shared Neighborhood Hits	235
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

VWF_MOUSE
NC score	0.178316 (rank : 456)	θ value	θ > 10 (rank : 1199)
Query Neighborhood Hits	600	Target Neighborhood Hits	381	Shared Neighborhood Hits	179
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

RAGE_MOUSE
NC score	0.177870 (rank : 457)	θ value	θ > 10 (rank : 1090)
Query Neighborhood Hits	600	Target Neighborhood Hits	295	Shared Neighborhood Hits	82
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

CD22_MOUSE
NC score	0.177282 (rank : 458)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	600	Target Neighborhood Hits	331	Shared Neighborhood Hits	76
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

JAM3_HUMAN
NC score	0.177030 (rank : 459)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	600	Target Neighborhood Hits	271	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

MUC18_MOUSE
NC score	0.176899 (rank : 460)	θ value	θ > 10 (rank : 966)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

LYAM3_HUMAN
NC score	0.176827 (rank : 461)	θ value	0.163984 (rank : 369)
Query Neighborhood Hits	600	Target Neighborhood Hits	378	Shared Neighborhood Hits	166
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MT1X_HUMAN
NC score	0.176736 (rank : 462)	θ value	5.27518 (rank : 525)
Query Neighborhood Hits	600	Target Neighborhood Hits	76	Shared Neighborhood Hits	58
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

SHBG_MOUSE
NC score	0.176632 (rank : 463)	θ value	1.06291 (rank : 427)
Query Neighborhood Hits	600	Target Neighborhood Hits	50	Shared Neighborhood Hits	42
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

HABP2_MOUSE
NC score	0.176458 (rank : 464)	θ value	5.27518 (rank : 517)
Query Neighborhood Hits	600	Target Neighborhood Hits	445	Shared Neighborhood Hits	190
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

EPHB6_MOUSE
NC score	0.176057 (rank : 465)	θ value	0.000602161 (rank : 253)
Query Neighborhood Hits	600	Target Neighborhood Hits	906	Shared Neighborhood Hits	179
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

BASI_HUMAN
NC score	0.175884 (rank : 466)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	600	Target Neighborhood Hits	211	Shared Neighborhood Hits	72
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

NPTN_MOUSE
NC score	0.175769 (rank : 467)	θ value	θ > 10 (rank : 981)
Query Neighborhood Hits	600	Target Neighborhood Hits	216	Shared Neighborhood Hits	75
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

IBP7_MOUSE
NC score	0.175655 (rank : 468)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	600	Target Neighborhood Hits	230	Shared Neighborhood Hits	92
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

EPHB4_HUMAN
NC score	0.175516 (rank : 469)	θ value	0.000270298 (rank : 245)
Query Neighborhood Hits	600	Target Neighborhood Hits	1056	Shared Neighborhood Hits	246
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

JAM3_MOUSE
NC score	0.175474 (rank : 470)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	600	Target Neighborhood Hits	286	Shared Neighborhood Hits	79
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

TNR22_MOUSE
NC score	0.175268 (rank : 471)	θ value	0.163984 (rank : 371)
Query Neighborhood Hits	600	Target Neighborhood Hits	97	Shared Neighborhood Hits	66
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

IBP7_HUMAN
NC score	0.174430 (rank : 472)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	600	Target Neighborhood Hits	220	Shared Neighborhood Hits	82
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

FAT2_HUMAN
NC score	0.172129 (rank : 473)	θ value	0.365318 (rank : 387)
Query Neighborhood Hits	600	Target Neighborhood Hits	507	Shared Neighborhood Hits	186
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

KIRR1_HUMAN
NC score	0.171560 (rank : 474)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	600	Target Neighborhood Hits	401	Shared Neighborhood Hits	81
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

JAM1_HUMAN
NC score	0.171460 (rank : 475)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	600	Target Neighborhood Hits	294	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

FCRL5_HUMAN
NC score	0.170964 (rank : 476)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	600	Target Neighborhood Hits	267	Shared Neighborhood Hits	69
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

KIRR3_HUMAN
NC score	0.170932 (rank : 477)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	600	Target Neighborhood Hits	302	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

EPHA3_MOUSE
NC score	0.169626 (rank : 478)	θ value	1.53129e-07 (rank : 161)
Query Neighborhood Hits	600	Target Neighborhood Hits	1009	Shared Neighborhood Hits	205
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

KIRR1_MOUSE
NC score	0.169437 (rank : 479)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	600	Target Neighborhood Hits	403	Shared Neighborhood Hits	81
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

TNR14_HUMAN
NC score	0.169230 (rank : 480)	θ value	0.279714 (rank : 383)
Query Neighborhood Hits	600	Target Neighborhood Hits	149	Shared Neighborhood Hits	102
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

LRIG2_MOUSE
NC score	0.169042 (rank : 481)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	600	Target Neighborhood Hits	586	Shared Neighborhood Hits	101
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG2_HUMAN
NC score	0.168938 (rank : 482)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	600	Target Neighborhood Hits	595	Shared Neighborhood Hits	101
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

BASI_MOUSE
NC score	0.168750 (rank : 483)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	600	Target Neighborhood Hits	238	Shared Neighborhood Hits	76
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

EPHA7_MOUSE
NC score	0.168363 (rank : 484)	θ value	3.08544e-08 (rank : 146)
Query Neighborhood Hits	600	Target Neighborhood Hits	1025	Shared Neighborhood Hits	211
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

LRIG1_HUMAN
NC score	0.168140 (rank : 485)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	600	Target Neighborhood Hits	654	Shared Neighborhood Hits	100
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

MT1A_HUMAN
NC score	0.167815 (rank : 486)	θ value	1.81305 (rank : 448)
Query Neighborhood Hits	600	Target Neighborhood Hits	74	Shared Neighborhood Hits	51
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

KIRR3_MOUSE
NC score	0.167635 (rank : 487)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

PTPRO_HUMAN
NC score	0.167527 (rank : 488)	θ value	0.000786445 (rank : 261)
Query Neighborhood Hits	600	Target Neighborhood Hits	139	Shared Neighborhood Hits	65
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

LRIG1_MOUSE
NC score	0.166614 (rank : 489)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	600	Target Neighborhood Hits	627	Shared Neighborhood Hits	100
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

JAM1_MOUSE
NC score	0.166468 (rank : 490)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	600	Target Neighborhood Hits	287	Shared Neighborhood Hits	80
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

CD22_HUMAN
NC score	0.166457 (rank : 491)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	600	Target Neighborhood Hits	365	Shared Neighborhood Hits	82
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

EPHB4_MOUSE
NC score	0.166349 (rank : 492)	θ value	0.00298849 (rank : 284)
Query Neighborhood Hits	600	Target Neighborhood Hits	1013	Shared Neighborhood Hits	220
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

CRLF1_HUMAN
NC score	0.165643 (rank : 493)	θ value	0.365318 (rank : 386)
Query Neighborhood Hits	600	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

TNR7_HUMAN
NC score	0.165625 (rank : 494)	θ value	0.365318 (rank : 392)
Query Neighborhood Hits	600	Target Neighborhood Hits	120	Shared Neighborhood Hits	87
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

MUSK_MOUSE
NC score	0.165471 (rank : 495)	θ value	θ > 10 (rank : 968)
Query Neighborhood Hits	600	Target Neighborhood Hits	1057	Shared Neighborhood Hits	125
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MUSK_HUMAN
NC score	0.165251 (rank : 496)	θ value	θ > 10 (rank : 967)
Query Neighborhood Hits	600	Target Neighborhood Hits	1074	Shared Neighborhood Hits	125
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

CRLF1_MOUSE
NC score	0.165106 (rank : 497)	θ value	0.279714 (rank : 378)
Query Neighborhood Hits	600	Target Neighborhood Hits	116	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CEAM5_HUMAN
NC score	0.165045 (rank : 498)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	600	Target Neighborhood Hits	343	Shared Neighborhood Hits	85
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

EPHA3_HUMAN
NC score	0.164247 (rank : 499)	θ value	3.41135e-07 (rank : 171)
Query Neighborhood Hits	600	Target Neighborhood Hits	1005	Shared Neighborhood Hits	204
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

LRIG3_MOUSE
NC score	0.163814 (rank : 500)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	600	Target Neighborhood Hits	611	Shared Neighborhood Hits	102
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

LYAM1_HUMAN
NC score	0.163175 (rank : 501)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	600	Target Neighborhood Hits	315	Shared Neighborhood Hits	144
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LRIG3_HUMAN
NC score	0.162518 (rank : 502)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	600	Target Neighborhood Hits	601	Shared Neighborhood Hits	103
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LYAM1_MOUSE
NC score	0.162183 (rank : 503)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	600	Target Neighborhood Hits	332	Shared Neighborhood Hits	152
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

TYRO3_HUMAN
NC score	0.161028 (rank : 504)	θ value	0.00134147 (rank : 269)
Query Neighborhood Hits	600	Target Neighborhood Hits	995	Shared Neighborhood Hits	146
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

EPHA4_MOUSE
NC score	0.160170 (rank : 505)	θ value	9.92553e-07 (rank : 183)
Query Neighborhood Hits	600	Target Neighborhood Hits	982	Shared Neighborhood Hits	188
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

KR410_HUMAN
NC score	0.160014 (rank : 506)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	600	Target Neighborhood Hits	156	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

FCRL2_HUMAN
NC score	0.159902 (rank : 507)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	600	Target Neighborhood Hits	251	Shared Neighborhood Hits	74
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

EPHB3_HUMAN
NC score	0.159775 (rank : 508)	θ value	1.29631e-06 (rank : 187)
Query Neighborhood Hits	600	Target Neighborhood Hits	996	Shared Neighborhood Hits	191
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

IGS4B_MOUSE
NC score	0.159456 (rank : 509)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	600	Target Neighborhood Hits	328	Shared Neighborhood Hits	81
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

TYRO3_MOUSE
NC score	0.159105 (rank : 510)	θ value	0.0193708 (rank : 324)
Query Neighborhood Hits	600	Target Neighborhood Hits	1007	Shared Neighborhood Hits	150
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

EPHA4_HUMAN
NC score	0.158938 (rank : 511)	θ value	7.59969e-07 (rank : 180)
Query Neighborhood Hits	600	Target Neighborhood Hits	975	Shared Neighborhood Hits	181
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

IGS4B_HUMAN
NC score	0.158520 (rank : 512)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	600	Target Neighborhood Hits	305	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

EPHB3_MOUSE
NC score	0.158118 (rank : 513)	θ value	3.41135e-07 (rank : 172)
Query Neighborhood Hits	600	Target Neighborhood Hits	996	Shared Neighborhood Hits	187
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHA8_MOUSE
NC score	0.157865 (rank : 514)	θ value	2.61198e-07 (rank : 169)
Query Neighborhood Hits	600	Target Neighborhood Hits	969	Shared Neighborhood Hits	173
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

VSIG2_HUMAN
NC score	0.157430 (rank : 515)	θ value	θ > 10 (rank : 1196)
Query Neighborhood Hits	600	Target Neighborhood Hits	321	Shared Neighborhood Hits	79
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

TEFF2_MOUSE
NC score	0.156867 (rank : 516)	θ value	θ > 10 (rank : 1140)
Query Neighborhood Hits	600	Target Neighborhood Hits	214	Shared Neighborhood Hits	115
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

LCE1A_HUMAN
NC score	0.156390 (rank : 517)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	600	Target Neighborhood Hits	47	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

MUC13_MOUSE
NC score	0.156190 (rank : 518)	θ value	θ > 10 (rank : 965)
Query Neighborhood Hits	600	Target Neighborhood Hits	447	Shared Neighborhood Hits	146
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

EPHA5_HUMAN
NC score	0.155329 (rank : 519)	θ value	9.92553e-07 (rank : 184)
Query Neighborhood Hits	600	Target Neighborhood Hits	1009	Shared Neighborhood Hits	188
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

LCE1F_HUMAN
NC score	0.155249 (rank : 520)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	600	Target Neighborhood Hits	48	Shared Neighborhood Hits	25
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

CEA20_HUMAN
NC score	0.154715 (rank : 521)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	600	Target Neighborhood Hits	251	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

EPHA8_HUMAN
NC score	0.154641 (rank : 522)	θ value	2.61198e-07 (rank : 168)
Query Neighborhood Hits	600	Target Neighborhood Hits	956	Shared Neighborhood Hits	167
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

LCE1D_HUMAN
NC score	0.154629 (rank : 523)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	600	Target Neighborhood Hits	44	Shared Neighborhood Hits	23
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

MERTK_HUMAN
NC score	0.154491 (rank : 524)	θ value	0.00035302 (rank : 250)
Query Neighborhood Hits	600	Target Neighborhood Hits	988	Shared Neighborhood Hits	142
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

LCE3A_HUMAN
NC score	0.154371 (rank : 525)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	600	Target Neighborhood Hits	29	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

TEFF2_HUMAN
NC score	0.153641 (rank : 526)	θ value	θ > 10 (rank : 1139)
Query Neighborhood Hits	600	Target Neighborhood Hits	211	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

LCE2D_HUMAN
NC score	0.153543 (rank : 527)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	600	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

CEAM1_MOUSE
NC score	0.152914 (rank : 528)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	600	Target Neighborhood Hits	326	Shared Neighborhood Hits	79
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

EPHA2_HUMAN
NC score	0.151225 (rank : 529)	θ value	0.00509761 (rank : 296)
Query Neighborhood Hits	600	Target Neighborhood Hits	1021	Shared Neighborhood Hits	190
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

MERTK_MOUSE
NC score	0.151188 (rank : 530)	θ value	0.00020696 (rank : 240)
Query Neighborhood Hits	600	Target Neighborhood Hits	974	Shared Neighborhood Hits	144
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

EPHA6_HUMAN
NC score	0.151103 (rank : 531)	θ value	0.00175202 (rank : 271)
Query Neighborhood Hits	600	Target Neighborhood Hits	959	Shared Neighborhood Hits	174
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

JAM2_HUMAN
NC score	0.150761 (rank : 532)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	600	Target Neighborhood Hits	304	Shared Neighborhood Hits	83
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

EPHB1_HUMAN
NC score	0.150500 (rank : 533)	θ value	2.88788e-06 (rank : 195)
Query Neighborhood Hits	600	Target Neighborhood Hits	988	Shared Neighborhood Hits	196
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

MT4_MOUSE
NC score	0.150441 (rank : 534)	θ value	θ > 10 (rank : 963)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

EPHAA_HUMAN
NC score	0.149642 (rank : 535)	θ value	0.0736092 (rank : 349)
Query Neighborhood Hits	600	Target Neighborhood Hits	960	Shared Neighborhood Hits	164
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

MFA3L_HUMAN
NC score	0.148974 (rank : 536)	θ value	θ > 10 (rank : 948)
Query Neighborhood Hits	600	Target Neighborhood Hits	230	Shared Neighborhood Hits	77
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

TDGF1_HUMAN
NC score	0.148943 (rank : 537)	θ value	θ > 10 (rank : 1132)
Query Neighborhood Hits	600	Target Neighborhood Hits	132	Shared Neighborhood Hits	93
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

LCE1E_HUMAN
NC score	0.148751 (rank : 538)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	600	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

VSIG2_MOUSE
NC score	0.148639 (rank : 539)	θ value	θ > 10 (rank : 1197)
Query Neighborhood Hits	600	Target Neighborhood Hits	316	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

ELTD1_HUMAN
NC score	0.148489 (rank : 540)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	600	Target Neighborhood Hits	269	Shared Neighborhood Hits	132
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

EPHA2_MOUSE
NC score	0.148009 (rank : 541)	θ value	0.00665767 (rank : 301)
Query Neighborhood Hits	600	Target Neighborhood Hits	1020	Shared Neighborhood Hits	193
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

MKS3_HUMAN
NC score	0.147655 (rank : 542)	θ value	0.21417 (rank : 376)
Query Neighborhood Hits	600	Target Neighborhood Hits	79	Shared Neighborhood Hits	71
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

CD45_HUMAN
NC score	0.147257 (rank : 543)	θ value	0.0113563 (rank : 307)
Query Neighborhood Hits	600	Target Neighborhood Hits	243	Shared Neighborhood Hits	72
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

UFO_MOUSE
NC score	0.146488 (rank : 544)	θ value	0.00175202 (rank : 276)
Query Neighborhood Hits	600	Target Neighborhood Hits	988	Shared Neighborhood Hits	154
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

EPHB2_HUMAN
NC score	0.145773 (rank : 545)	θ value	0.000270298 (rank : 243)
Query Neighborhood Hits	600	Target Neighborhood Hits	983	Shared Neighborhood Hits	181
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

TDGF2_HUMAN
NC score	0.145738 (rank : 546)	θ value	θ > 10 (rank : 1134)
Query Neighborhood Hits	600	Target Neighborhood Hits	131	Shared Neighborhood Hits	92
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

EPHB2_MOUSE
NC score	0.145716 (rank : 547)	θ value	0.000270298 (rank : 244)
Query Neighborhood Hits	600	Target Neighborhood Hits	982	Shared Neighborhood Hits	181
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHA6_MOUSE
NC score	0.145628 (rank : 548)	θ value	0.00390308 (rank : 289)
Query Neighborhood Hits	600	Target Neighborhood Hits	946	Shared Neighborhood Hits	160
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

JAM2_MOUSE
NC score	0.144532 (rank : 549)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

SIG11_HUMAN
NC score	0.144080 (rank : 550)	θ value	θ > 10 (rank : 1112)
Query Neighborhood Hits	600	Target Neighborhood Hits	273	Shared Neighborhood Hits	81
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

SIG10_HUMAN
NC score	0.143749 (rank : 551)	θ value	θ > 10 (rank : 1111)
Query Neighborhood Hits	600	Target Neighborhood Hits	363	Shared Neighborhood Hits	84
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

NRX3B_HUMAN
NC score	0.143740 (rank : 552)	θ value	θ > 10 (rank : 989)
Query Neighborhood Hits	600	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HDB5	Gene names	NRXN3, KIAA0743
Domain Architecture	No domain graphic available
Description	Neurexin-3-beta precursor (Neurexin III-beta).

INSRR_HUMAN
NC score	0.143610 (rank : 553)	θ value	9.92553e-07 (rank : 185)
Query Neighborhood Hits	600	Target Neighborhood Hits	950	Shared Neighborhood Hits	179
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
NC score	0.143018 (rank : 554)	θ value	7.59969e-07 (rank : 181)
Query Neighborhood Hits	600	Target Neighborhood Hits	961	Shared Neighborhood Hits	186
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LCE2B_HUMAN
NC score	0.142975 (rank : 555)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	600	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

UFO_HUMAN
NC score	0.142779 (rank : 556)	θ value	0.00509761 (rank : 300)
Query Neighborhood Hits	600	Target Neighborhood Hits	981	Shared Neighborhood Hits	153
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

IL27B_HUMAN
NC score	0.142510 (rank : 557)	θ value	0.62314 (rank : 404)
Query Neighborhood Hits	600	Target Neighborhood Hits	80	Shared Neighborhood Hits	61
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

MT1H_HUMAN
NC score	0.141309 (rank : 558)	θ value	1.38821 (rank : 433)
Query Neighborhood Hits	600	Target Neighborhood Hits	78	Shared Neighborhood Hits	56
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT2_MOUSE
NC score	0.141165 (rank : 559)	θ value	5.27518 (rank : 526)
Query Neighborhood Hits	600	Target Neighborhood Hits	81	Shared Neighborhood Hits	59
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

NRX1B_HUMAN
NC score	0.140118 (rank : 560)	θ value	θ > 10 (rank : 987)
Query Neighborhood Hits	600	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	P58400	Gene names	NRXN1
Domain Architecture	No domain graphic available
Description	Neurexin-1-beta precursor (Neurexin I-beta).

CD45_MOUSE
NC score	0.139739 (rank : 561)	θ value	0.00102713 (rank : 262)
Query Neighborhood Hits	600	Target Neighborhood Hits	178	Shared Neighborhood Hits	59
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

BMPER_MOUSE
NC score	0.138595 (rank : 562)	θ value	3.0926 (rank : 473)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	106
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

ATL3_HUMAN
NC score	0.137912 (rank : 563)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	600	Target Neighborhood Hits	414	Shared Neighborhood Hits	118
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

LRP10_HUMAN
NC score	0.137620 (rank : 564)	θ value	0.0736092 (rank : 350)
Query Neighborhood Hits	600	Target Neighborhood Hits	197	Shared Neighborhood Hits	77
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

ROS_HUMAN
NC score	0.137290 (rank : 565)	θ value	1.99992e-07 (rank : 165)
Query Neighborhood Hits	600	Target Neighborhood Hits	907	Shared Neighborhood Hits	165
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

VGFR1_HUMAN
NC score	0.136712 (rank : 566)	θ value	θ > 10 (rank : 1189)
Query Neighborhood Hits	600	Target Neighborhood Hits	1109	Shared Neighborhood Hits	123
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

HCFC1_MOUSE
NC score	0.136161 (rank : 567)	θ value	0.00665767 (rank : 302)
Query Neighborhood Hits	600	Target Neighborhood Hits	348	Shared Neighborhood Hits	82
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

VGFR1_MOUSE
NC score	0.136123 (rank : 568)	θ value	θ > 10 (rank : 1190)
Query Neighborhood Hits	600	Target Neighborhood Hits	1118	Shared Neighborhood Hits	124
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

CEAM1_HUMAN
NC score	0.135553 (rank : 569)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	600	Target Neighborhood Hits	348	Shared Neighborhood Hits	80
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

RELN_MOUSE
NC score	0.135224 (rank : 570)	θ value	θ > 10 (rank : 1094)
Query Neighborhood Hits	600	Target Neighborhood Hits	235	Shared Neighborhood Hits	139
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

LCE2C_HUMAN
NC score	0.134503 (rank : 571)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	600	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

KRA42_HUMAN
NC score	0.133732 (rank : 572)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	600	Target Neighborhood Hits	149	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

PGCB_MOUSE
NC score	0.133395 (rank : 573)	θ value	θ > 10 (rank : 1010)
Query Neighborhood Hits	600	Target Neighborhood Hits	459	Shared Neighborhood Hits	157
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

TNR3_MOUSE
NC score	0.133316 (rank : 574)	θ value	6.88961 (rank : 565)
Query Neighborhood Hits	600	Target Neighborhood Hits	113	Shared Neighborhood Hits	74
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

MYLK_HUMAN
NC score	0.132410 (rank : 575)	θ value	1.81305 (rank : 451)
Query Neighborhood Hits	600	Target Neighborhood Hits	1328	Shared Neighborhood Hits	150
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

EPHA1_HUMAN
NC score	0.132245 (rank : 576)	θ value	0.00035302 (rank : 247)
Query Neighborhood Hits	600	Target Neighborhood Hits	997	Shared Neighborhood Hits	183
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

CT127_HUMAN
NC score	0.132126 (rank : 577)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	600	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

OBSCN_HUMAN
NC score	0.132041 (rank : 578)	θ value	0.365318 (rank : 390)
Query Neighborhood Hits	600	Target Neighborhood Hits	1931	Shared Neighborhood Hits	174
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

CT075_HUMAN
NC score	0.132013 (rank : 579)	θ value	0.00134147 (rank : 265)
Query Neighborhood Hits	600	Target Neighborhood Hits	387	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

MYLK_MOUSE
NC score	0.131850 (rank : 580)	θ value	1.81305 (rank : 452)
Query Neighborhood Hits	600	Target Neighborhood Hits	1489	Shared Neighborhood Hits	157
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

LRP10_MOUSE
NC score	0.131661 (rank : 581)	θ value	0.125558 (rank : 363)
Query Neighborhood Hits	600	Target Neighborhood Hits	169	Shared Neighborhood Hits	73
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

CSPG4_HUMAN
NC score	0.131022 (rank : 582)	θ value	0.0113563 (rank : 308)
Query Neighborhood Hits	600	Target Neighborhood Hits	112	Shared Neighborhood Hits	41
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CD166_MOUSE
NC score	0.131010 (rank : 583)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	600	Target Neighborhood Hits	252	Shared Neighborhood Hits	71
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

VSIG4_HUMAN
NC score	0.130954 (rank : 584)	θ value	θ > 10 (rank : 1198)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

LCE2A_HUMAN
NC score	0.130849 (rank : 585)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	600	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

VGFR2_HUMAN
NC score	0.130496 (rank : 586)	θ value	θ > 10 (rank : 1191)
Query Neighborhood Hits	600	Target Neighborhood Hits	1103	Shared Neighborhood Hits	123
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

SPEG_MOUSE
NC score	0.130331 (rank : 587)	θ value	0.0193708 (rank : 322)
Query Neighborhood Hits	600	Target Neighborhood Hits	1959	Shared Neighborhood Hits	161
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_HUMAN
NC score	0.130212 (rank : 588)	θ value	0.0252991 (rank : 331)
Query Neighborhood Hits	600	Target Neighborhood Hits	1762	Shared Neighborhood Hits	161
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

RELN_HUMAN
NC score	0.130105 (rank : 589)	θ value	θ > 10 (rank : 1093)
Query Neighborhood Hits	600	Target Neighborhood Hits	233	Shared Neighborhood Hits	136
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

MFA3L_MOUSE
NC score	0.129978 (rank : 590)	θ value	θ > 10 (rank : 949)
Query Neighborhood Hits	600	Target Neighborhood Hits	214	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

VGFR2_MOUSE
NC score	0.129771 (rank : 591)	θ value	θ > 10 (rank : 1192)
Query Neighborhood Hits	600	Target Neighborhood Hits	1089	Shared Neighborhood Hits	123
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

FGFR4_MOUSE
NC score	0.128768 (rank : 592)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	600	Target Neighborhood Hits	1026	Shared Neighborhood Hits	124
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

HGFA_HUMAN
NC score	0.128617 (rank : 593)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	600	Target Neighborhood Hits	436	Shared Neighborhood Hits	167
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

MT1B_HUMAN
NC score	0.128434 (rank : 594)	θ value	5.27518 (rank : 524)
Query Neighborhood Hits	600	Target Neighborhood Hits	87	Shared Neighborhood Hits	59
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

EPHA1_MOUSE
NC score	0.128421 (rank : 595)	θ value	0.0148317 (rank : 313)
Query Neighborhood Hits	600	Target Neighborhood Hits	958	Shared Neighborhood Hits	180
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

INSR_MOUSE
NC score	0.127151 (rank : 596)	θ value	4.45536e-07 (rank : 176)
Query Neighborhood Hits	600	Target Neighborhood Hits	968	Shared Neighborhood Hits	164
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

CO6_HUMAN
NC score	0.126033 (rank : 597)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	600	Target Neighborhood Hits	331	Shared Neighborhood Hits	132
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

EPHA5_MOUSE
NC score	0.125872 (rank : 598)	θ value	0.00035302 (rank : 248)
Query Neighborhood Hits	600	Target Neighborhood Hits	950	Shared Neighborhood Hits	146
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

FGFR4_HUMAN
NC score	0.125754 (rank : 599)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	600	Target Neighborhood Hits	1037	Shared Neighborhood Hits	125
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

KRA24_HUMAN
NC score	0.125432 (rank : 600)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	600	Target Neighborhood Hits	192	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

CILP2_HUMAN
NC score	0.125346 (rank : 601)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	600	Target Neighborhood Hits	307	Shared Neighborhood Hits	94
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CSPG4_MOUSE
NC score	0.125140 (rank : 602)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	600	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

IGF1R_MOUSE
NC score	0.125006 (rank : 603)	θ value	4.92598e-06 (rank : 203)
Query Neighborhood Hits	600	Target Neighborhood Hits	973	Shared Neighborhood Hits	176
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

RIMB2_HUMAN
NC score	0.124962 (rank : 604)	θ value	0.0563607 (rank : 347)
Query Neighborhood Hits	600	Target Neighborhood Hits	263	Shared Neighborhood Hits	62
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

INSR_HUMAN
NC score	0.124880 (rank : 605)	θ value	1.29631e-06 (rank : 188)
Query Neighborhood Hits	600	Target Neighborhood Hits	963	Shared Neighborhood Hits	159
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

FGFR3_MOUSE
NC score	0.124828 (rank : 606)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	600	Target Neighborhood Hits	1059	Shared Neighborhood Hits	126
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

IGF1R_HUMAN
NC score	0.124649 (rank : 607)	θ value	4.92598e-06 (rank : 202)
Query Neighborhood Hits	600	Target Neighborhood Hits	977	Shared Neighborhood Hits	174
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

TNR9_HUMAN
NC score	0.123974 (rank : 608)	θ value	0.21417 (rank : 377)
Query Neighborhood Hits	600	Target Neighborhood Hits	166	Shared Neighborhood Hits	112
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

MUC2_HUMAN
NC score	0.123960 (rank : 609)	θ value	1.81305 (rank : 450)
Query Neighborhood Hits	600	Target Neighborhood Hits	906	Shared Neighborhood Hits	169
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

BMPER_HUMAN
NC score	0.123690 (rank : 610)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	600	Target Neighborhood Hits	175	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

MT4_HUMAN
NC score	0.123467 (rank : 611)	θ value	θ > 10 (rank : 962)
Query Neighborhood Hits	600	Target Neighborhood Hits	83	Shared Neighborhood Hits	55
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

HGFA_MOUSE
NC score	0.123235 (rank : 612)	θ value	0.813845 (rank : 413)
Query Neighborhood Hits	600	Target Neighborhood Hits	419	Shared Neighborhood Hits	164
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

MT1_MOUSE
NC score	0.122978 (rank : 613)	θ value	θ > 10 (rank : 960)
Query Neighborhood Hits	600	Target Neighborhood Hits	72	Shared Neighborhood Hits	44
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MUC13_HUMAN
NC score	0.122742 (rank : 614)	θ value	θ > 10 (rank : 964)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	84
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

PGCB_HUMAN
NC score	0.122306 (rank : 615)	θ value	θ > 10 (rank : 1009)
Query Neighborhood Hits	600	Target Neighborhood Hits	478	Shared Neighborhood Hits	153
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

GPA33_MOUSE
NC score	0.122103 (rank : 616)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	600	Target Neighborhood Hits	294	Shared Neighborhood Hits	69
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

FGFR3_HUMAN
NC score	0.122035 (rank : 617)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	600	Target Neighborhood Hits	1042	Shared Neighborhood Hits	124
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

FGFR1_HUMAN
NC score	0.121983 (rank : 618)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	600	Target Neighborhood Hits	1069	Shared Neighborhood Hits	125
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR1_MOUSE
NC score	0.121862 (rank : 619)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	600	Target Neighborhood Hits	1068	Shared Neighborhood Hits	125
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

HCFC1_HUMAN
NC score	0.121835 (rank : 620)	θ value	0.0252991 (rank : 327)
Query Neighborhood Hits	600	Target Neighborhood Hits	331	Shared Neighborhood Hits	69
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

FGFR2_HUMAN
NC score	0.121638 (rank : 621)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	600	Target Neighborhood Hits	1062	Shared Neighborhood Hits	124
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

MFGM_HUMAN
NC score	0.121560 (rank : 622)	θ value	θ > 10 (rank : 952)
Query Neighborhood Hits	600	Target Neighborhood Hits	150	Shared Neighborhood Hits	93
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

TNR19_MOUSE
NC score	0.121534 (rank : 623)	θ value	3.0926 (rank : 488)
Query Neighborhood Hits	600	Target Neighborhood Hits	100	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR7_MOUSE
NC score	0.121300 (rank : 624)	θ value	2.36792 (rank : 469)
Query Neighborhood Hits	600	Target Neighborhood Hits	112	Shared Neighborhood Hits	77
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR5_MOUSE
NC score	0.119691 (rank : 625)	θ value	4.03905 (rank : 508)
Query Neighborhood Hits	600	Target Neighborhood Hits	131	Shared Neighborhood Hits	84
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

RIMB2_MOUSE
NC score	0.119022 (rank : 626)	θ value	1.81305 (rank : 457)
Query Neighborhood Hits	600	Target Neighborhood Hits	246	Shared Neighborhood Hits	55
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

CD166_HUMAN
NC score	0.118865 (rank : 627)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	600	Target Neighborhood Hits	247	Shared Neighborhood Hits	68
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

LRFN4_HUMAN
NC score	0.118677 (rank : 628)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	600	Target Neighborhood Hits	462	Shared Neighborhood Hits	102
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

GPA33_HUMAN
NC score	0.118669 (rank : 629)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	600	Target Neighborhood Hits	273	Shared Neighborhood Hits	65
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

VEGFC_HUMAN
NC score	0.118225 (rank : 630)	θ value	4.03905 (rank : 510)
Query Neighborhood Hits	600	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

FGFR2_MOUSE
NC score	0.117754 (rank : 631)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	600	Target Neighborhood Hits	1062	Shared Neighborhood Hits	123
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

IL1R2_HUMAN
NC score	0.117235 (rank : 632)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	600	Target Neighborhood Hits	153	Shared Neighborhood Hits	61
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

LORI_MOUSE
NC score	0.117199 (rank : 633)	θ value	6.88961 (rank : 552)
Query Neighborhood Hits	600	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRC21_MOUSE
NC score	0.117178 (rank : 634)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	600	Target Neighborhood Hits	462	Shared Neighborhood Hits	107
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

ROR2_MOUSE
NC score	0.116666 (rank : 635)	θ value	θ > 10 (rank : 1102)
Query Neighborhood Hits	600	Target Neighborhood Hits	1000	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

FA12_HUMAN
NC score	0.115425 (rank : 636)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	600	Target Neighborhood Hits	425	Shared Neighborhood Hits	166
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

TNR3_HUMAN
NC score	0.115330 (rank : 637)	θ value	θ > 10 (rank : 1154)
Query Neighborhood Hits	600	Target Neighborhood Hits	145	Shared Neighborhood Hits	72
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

I27RA_HUMAN
NC score	0.115265 (rank : 638)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	600	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

LRC21_HUMAN
NC score	0.114999 (rank : 639)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	600	Target Neighborhood Hits	456	Shared Neighborhood Hits	103
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

SIGL5_MOUSE
NC score	0.114789 (rank : 640)	θ value	θ > 10 (rank : 1115)
Query Neighborhood Hits	600	Target Neighborhood Hits	271	Shared Neighborhood Hits	72
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

LRFN4_MOUSE
NC score	0.114688 (rank : 641)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	600	Target Neighborhood Hits	442	Shared Neighborhood Hits	96
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

VGFR3_HUMAN
NC score	0.114159 (rank : 642)	θ value	θ > 10 (rank : 1193)
Query Neighborhood Hits	600	Target Neighborhood Hits	1037	Shared Neighborhood Hits	123
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

CEAM6_HUMAN
NC score	0.114028 (rank : 643)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	600	Target Neighborhood Hits	308	Shared Neighborhood Hits	81
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

VGFR3_MOUSE
NC score	0.113326 (rank : 644)	θ value	θ > 10 (rank : 1194)
Query Neighborhood Hits	600	Target Neighborhood Hits	1056	Shared Neighborhood Hits	126
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

ROR2_HUMAN
NC score	0.112904 (rank : 645)	θ value	θ > 10 (rank : 1101)
Query Neighborhood Hits	600	Target Neighborhood Hits	1014	Shared Neighborhood Hits	129
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

TNR8_HUMAN
NC score	0.112750 (rank : 646)	θ value	0.813845 (rank : 418)
Query Neighborhood Hits	600	Target Neighborhood Hits	198	Shared Neighborhood Hits	85
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

RECK_HUMAN
NC score	0.111950 (rank : 647)	θ value	θ > 10 (rank : 1091)
Query Neighborhood Hits	600	Target Neighborhood Hits	189	Shared Neighborhood Hits	93
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

GPR98_HUMAN
NC score	0.111746 (rank : 648)	θ value	2.79066e-09 (rank : 127)
Query Neighborhood Hits	600	Target Neighborhood Hits	202	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

VEGFC_MOUSE
NC score	0.111695 (rank : 649)	θ value	θ > 10 (rank : 1188)
Query Neighborhood Hits	600	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

PTPRE_MOUSE
NC score	0.111377 (rank : 650)	θ value	θ > 10 (rank : 1077)
Query Neighborhood Hits	600	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRZ_HUMAN
NC score	0.111281 (rank : 651)	θ value	6.88961 (rank : 557)
Query Neighborhood Hits	600	Target Neighborhood Hits	255	Shared Neighborhood Hits	52
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

MMRN1_HUMAN
NC score	0.111226 (rank : 652)	θ value	θ > 10 (rank : 954)
Query Neighborhood Hits	600	Target Neighborhood Hits	636	Shared Neighborhood Hits	107
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

PTPRE_HUMAN
NC score	0.111149 (rank : 653)	θ value	θ > 10 (rank : 1076)
Query Neighborhood Hits	600	Target Neighborhood Hits	92	Shared Neighborhood Hits	21
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.111084 (rank : 654)	θ value	θ > 10 (rank : 1074)
Query Neighborhood Hits	600	Target Neighborhood Hits	101	Shared Neighborhood Hits	25
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
NC score	0.110800 (rank : 655)	θ value	θ > 10 (rank : 1075)
Query Neighborhood Hits	600	Target Neighborhood Hits	93	Shared Neighborhood Hits	22
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

ROR1_HUMAN
NC score	0.110326 (rank : 656)	θ value	θ > 10 (rank : 1099)
Query Neighborhood Hits	600	Target Neighborhood Hits	1018	Shared Neighborhood Hits	131
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

PTPRG_HUMAN
NC score	0.110213 (rank : 657)	θ value	θ > 10 (rank : 1078)
Query Neighborhood Hits	600	Target Neighborhood Hits	231	Shared Neighborhood Hits	63
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

CSF1R_MOUSE
NC score	0.109829 (rank : 658)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	600	Target Neighborhood Hits	983	Shared Neighborhood Hits	116
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

LRFN2_MOUSE
NC score	0.109652 (rank : 659)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	600	Target Neighborhood Hits	450	Shared Neighborhood Hits	96
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LEPR_MOUSE
NC score	0.109478 (rank : 660)	θ value	0.00390308 (rank : 291)
Query Neighborhood Hits	600	Target Neighborhood Hits	109	Shared Neighborhood Hits	57
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

PTPRG_MOUSE
NC score	0.109468 (rank : 661)	θ value	θ > 10 (rank : 1079)
Query Neighborhood Hits	600	Target Neighborhood Hits	260	Shared Neighborhood Hits	63
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

LRFN3_MOUSE
NC score	0.109398 (rank : 662)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	600	Target Neighborhood Hits	455	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

EMR3_HUMAN
NC score	0.109331 (rank : 663)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	600	Target Neighborhood Hits	245	Shared Neighborhood Hits	104
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

NTRK2_HUMAN
NC score	0.109132 (rank : 664)	θ value	θ > 10 (rank : 993)
Query Neighborhood Hits	600	Target Neighborhood Hits	1081	Shared Neighborhood Hits	130
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

ROR1_MOUSE
NC score	0.108769 (rank : 665)	θ value	θ > 10 (rank : 1100)
Query Neighborhood Hits	600	Target Neighborhood Hits	1025	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

LRFN2_HUMAN
NC score	0.108764 (rank : 666)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	600	Target Neighborhood Hits	450	Shared Neighborhood Hits	95
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

NTRK3_HUMAN
NC score	0.108525 (rank : 667)	θ value	θ > 10 (rank : 995)
Query Neighborhood Hits	600	Target Neighborhood Hits	1115	Shared Neighborhood Hits	132
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

FSTL3_HUMAN
NC score	0.108490 (rank : 668)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	600	Target Neighborhood Hits	162	Shared Neighborhood Hits	84
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

NTRK2_MOUSE
NC score	0.108431 (rank : 669)	θ value	θ > 10 (rank : 994)
Query Neighborhood Hits	600	Target Neighborhood Hits	1088	Shared Neighborhood Hits	130
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

PGH2_MOUSE
NC score	0.108307 (rank : 670)	θ value	θ > 10 (rank : 1020)
Query Neighborhood Hits	600	Target Neighborhood Hits	113	Shared Neighborhood Hits	81
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

DUET_HUMAN
NC score	0.107661 (rank : 671)	θ value	0.00869519 (rank : 305)
Query Neighborhood Hits	600	Target Neighborhood Hits	1220	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

I12R1_HUMAN
NC score	0.107013 (rank : 672)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	600	Target Neighborhood Hits	78	Shared Neighborhood Hits	64
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

FA10_MOUSE
NC score	0.106760 (rank : 673)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	600	Target Neighborhood Hits	435	Shared Neighborhood Hits	165
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

TNR8_MOUSE
NC score	0.106006 (rank : 674)	θ value	θ > 10 (rank : 1159)
Query Neighborhood Hits	600	Target Neighborhood Hits	208	Shared Neighborhood Hits	84
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

UNC5D_MOUSE
NC score	0.105555 (rank : 675)	θ value	θ > 10 (rank : 1181)
Query Neighborhood Hits	600	Target Neighborhood Hits	268	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

CILP1_HUMAN
NC score	0.105523 (rank : 676)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	600	Target Neighborhood Hits	266	Shared Neighborhood Hits	96
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

FA10_HUMAN
NC score	0.105144 (rank : 677)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	600	Target Neighborhood Hits	431	Shared Neighborhood Hits	168
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

CT075_MOUSE
NC score	0.105130 (rank : 678)	θ value	0.0252991 (rank : 326)
Query Neighborhood Hits	600	Target Neighborhood Hits	358	Shared Neighborhood Hits	69
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

LRFN3_HUMAN
NC score	0.104729 (rank : 679)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	600	Target Neighborhood Hits	444	Shared Neighborhood Hits	98
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

TNR11_HUMAN
NC score	0.104057 (rank : 680)	θ value	4.03905 (rank : 507)
Query Neighborhood Hits	600	Target Neighborhood Hits	135	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

MT1E_HUMAN
NC score	0.103784 (rank : 681)	θ value	3.0926 (rank : 480)
Query Neighborhood Hits	600	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

PSG3_HUMAN
NC score	0.103189 (rank : 682)	θ value	θ > 10 (rank : 1034)
Query Neighborhood Hits	600	Target Neighborhood Hits	242	Shared Neighborhood Hits	75
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

PROC_MOUSE
NC score	0.102611 (rank : 683)	θ value	θ > 10 (rank : 1027)
Query Neighborhood Hits	600	Target Neighborhood Hits	426	Shared Neighborhood Hits	163
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

GPR98_MOUSE
NC score	0.102557 (rank : 684)	θ value	2.61198e-07 (rank : 170)
Query Neighborhood Hits	600	Target Neighborhood Hits	206	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

IL1R2_MOUSE
NC score	0.102485 (rank : 685)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	600	Target Neighborhood Hits	125	Shared Neighborhood Hits	51
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

PGFRA_MOUSE
NC score	0.102438 (rank : 686)	θ value	θ > 10 (rank : 1012)
Query Neighborhood Hits	600	Target Neighborhood Hits	975	Shared Neighborhood Hits	119
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

UNC5D_HUMAN
NC score	0.102089 (rank : 687)	θ value	θ > 10 (rank : 1180)
Query Neighborhood Hits	600	Target Neighborhood Hits	267	Shared Neighborhood Hits	88
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

CORIN_HUMAN
NC score	0.102005 (rank : 688)	θ value	0.125558 (rank : 361)
Query Neighborhood Hits	600	Target Neighborhood Hits	453	Shared Neighborhood Hits	155
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

PGFRA_HUMAN
NC score	0.101891 (rank : 689)	θ value	θ > 10 (rank : 1011)
Query Neighborhood Hits	600	Target Neighborhood Hits	980	Shared Neighborhood Hits	117
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

NRX2B_HUMAN
NC score	0.101731 (rank : 690)	θ value	θ > 10 (rank : 988)
Query Neighborhood Hits	600	Target Neighborhood Hits	481	Shared Neighborhood Hits	42
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

CILP1_MOUSE
NC score	0.100987 (rank : 691)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	600	Target Neighborhood Hits	282	Shared Neighborhood Hits	88
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

LRP3_HUMAN
NC score	0.100939 (rank : 692)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	600	Target Neighborhood Hits	280	Shared Neighborhood Hits	96
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

PSG4_HUMAN
NC score	0.100831 (rank : 693)	θ value	θ > 10 (rank : 1035)
Query Neighborhood Hits	600	Target Neighborhood Hits	243	Shared Neighborhood Hits	70
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

FA9_HUMAN
NC score	0.100221 (rank : 694)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	600	Target Neighborhood Hits	421	Shared Neighborhood Hits	159
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

LRFN5_MOUSE
NC score	0.099931 (rank : 695)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	600	Target Neighborhood Hits	472	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

ESAM_HUMAN
NC score	0.099807 (rank : 696)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	600	Target Neighborhood Hits	251	Shared Neighborhood Hits	70
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

UROL1_MOUSE
NC score	0.099715 (rank : 697)	θ value	θ > 10 (rank : 1183)
Query Neighborhood Hits	600	Target Neighborhood Hits	235	Shared Neighborhood Hits	114
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

LEPR_HUMAN
NC score	0.099701 (rank : 698)	θ value	4.03905 (rank : 499)
Query Neighborhood Hits	600	Target Neighborhood Hits	112	Shared Neighborhood Hits	61
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

PGCA_HUMAN
NC score	0.099544 (rank : 699)	θ value	θ > 10 (rank : 1008)
Query Neighborhood Hits	600	Target Neighborhood Hits	821	Shared Neighborhood Hits	161
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

CD276_HUMAN
NC score	0.099339 (rank : 700)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	600	Target Neighborhood Hits	261	Shared Neighborhood Hits	51
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

I12R1_MOUSE
NC score	0.099254 (rank : 701)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	600	Target Neighborhood Hits	70	Shared Neighborhood Hits	54
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

KIT_MOUSE
NC score	0.099236 (rank : 702)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	600	Target Neighborhood Hits	949	Shared Neighborhood Hits	115
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

LCE4A_HUMAN
NC score	0.099159 (rank : 703)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	600	Target Neighborhood Hits	26	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

ANKF1_HUMAN
NC score	0.098979 (rank : 704)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	600	Target Neighborhood Hits	126	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

LRP6_HUMAN
NC score	0.098952 (rank : 705)	θ value	5.27518 (rank : 520)
Query Neighborhood Hits	600	Target Neighborhood Hits	235	Shared Neighborhood Hits	99
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

CEAM8_HUMAN
NC score	0.098699 (rank : 706)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	600	Target Neighborhood Hits	264	Shared Neighborhood Hits	77
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

FSTL3_MOUSE
NC score	0.098171 (rank : 707)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	600	Target Neighborhood Hits	152	Shared Neighborhood Hits	76
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

PSG8_HUMAN
NC score	0.098017 (rank : 708)	θ value	θ > 10 (rank : 1039)
Query Neighborhood Hits	600	Target Neighborhood Hits	239	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

PGFRB_MOUSE
NC score	0.097866 (rank : 709)	θ value	θ > 10 (rank : 1014)
Query Neighborhood Hits	600	Target Neighborhood Hits	960	Shared Neighborhood Hits	113
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

LRRN1_HUMAN
NC score	0.097859 (rank : 710)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	600	Target Neighborhood Hits	518	Shared Neighborhood Hits	104
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRFN5_HUMAN
NC score	0.097597 (rank : 711)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	600	Target Neighborhood Hits	464	Shared Neighborhood Hits	90
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

CXAR_HUMAN
NC score	0.097288 (rank : 712)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	600	Target Neighborhood Hits	245	Shared Neighborhood Hits	58
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

TNR26_MOUSE
NC score	0.097187 (rank : 713)	θ value	θ > 10 (rank : 1153)
Query Neighborhood Hits	600	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

PGH2_HUMAN
NC score	0.096352 (rank : 714)	θ value	θ > 10 (rank : 1019)
Query Neighborhood Hits	600	Target Neighborhood Hits	103	Shared Neighborhood Hits	72
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

FA7_HUMAN
NC score	0.096256 (rank : 715)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	600	Target Neighborhood Hits	404	Shared Neighborhood Hits	155
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

LRP5_MOUSE
NC score	0.096053 (rank : 716)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	99
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

KR413_HUMAN
NC score	0.095968 (rank : 717)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	600	Target Neighborhood Hits	112	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

IRPL2_HUMAN
NC score	0.095944 (rank : 718)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

MT1L_HUMAN
NC score	0.095850 (rank : 719)	θ value	θ > 10 (rank : 958)
Query Neighborhood Hits	600	Target Neighborhood Hits	73	Shared Neighborhood Hits	49
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

LRP6_MOUSE
NC score	0.095754 (rank : 720)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	600	Target Neighborhood Hits	232	Shared Neighborhood Hits	94
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MT1G_HUMAN
NC score	0.095389 (rank : 721)	θ value	θ > 10 (rank : 957)
Query Neighborhood Hits	600	Target Neighborhood Hits	63	Shared Neighborhood Hits	42
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

PSG7_HUMAN
NC score	0.095375 (rank : 722)	θ value	θ > 10 (rank : 1038)
Query Neighborhood Hits	600	Target Neighborhood Hits	239	Shared Neighborhood Hits	71
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

PSG11_HUMAN
NC score	0.095302 (rank : 723)	θ value	θ > 10 (rank : 1031)
Query Neighborhood Hits	600	Target Neighborhood Hits	223	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

IRPL2_MOUSE
NC score	0.095198 (rank : 724)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	600	Target Neighborhood Hits	195	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

IGS21_HUMAN
NC score	0.094977 (rank : 725)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	600	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

MCSP_MOUSE
NC score	0.094725 (rank : 726)	θ value	θ > 10 (rank : 942)
Query Neighborhood Hits	600	Target Neighborhood Hits	108	Shared Neighborhood Hits	41
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

LRRN3_HUMAN
NC score	0.094537 (rank : 727)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	600	Target Neighborhood Hits	461	Shared Neighborhood Hits	100
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

UNC5A_HUMAN
NC score	0.094143 (rank : 728)	θ value	θ > 10 (rank : 1174)
Query Neighborhood Hits	600	Target Neighborhood Hits	198	Shared Neighborhood Hits	72
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

LRRN1_MOUSE
NC score	0.094031 (rank : 729)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	600	Target Neighborhood Hits	508	Shared Neighborhood Hits	103
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

CO7_HUMAN
NC score	0.093917 (rank : 730)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	600	Target Neighborhood Hits	278	Shared Neighborhood Hits	115
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

PSG1_HUMAN
NC score	0.093629 (rank : 731)	θ value	θ > 10 (rank : 1032)
Query Neighborhood Hits	600	Target Neighborhood Hits	232	Shared Neighborhood Hits	73
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

RECK_MOUSE
NC score	0.093587 (rank : 732)	θ value	θ > 10 (rank : 1092)
Query Neighborhood Hits	600	Target Neighborhood Hits	158	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

PSG6_HUMAN
NC score	0.093357 (rank : 733)	θ value	θ > 10 (rank : 1037)
Query Neighborhood Hits	600	Target Neighborhood Hits	231	Shared Neighborhood Hits	69
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

TNR6B_HUMAN
NC score	0.093289 (rank : 734)	θ value	θ > 10 (rank : 1156)
Query Neighborhood Hits	600	Target Neighborhood Hits	103	Shared Neighborhood Hits	67
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

KIT_HUMAN
NC score	0.093059 (rank : 735)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	600	Target Neighborhood Hits	953	Shared Neighborhood Hits	115
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

TECTA_MOUSE
NC score	0.092772 (rank : 736)	θ value	θ > 10 (rank : 1136)
Query Neighborhood Hits	600	Target Neighborhood Hits	244	Shared Neighborhood Hits	133
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TNR11_MOUSE
NC score	0.092759 (rank : 737)	θ value	3.0926 (rank : 487)
Query Neighborhood Hits	600	Target Neighborhood Hits	121	Shared Neighborhood Hits	69
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

ODFP_MOUSE
NC score	0.092578 (rank : 738)	θ value	θ > 10 (rank : 997)
Query Neighborhood Hits	600	Target Neighborhood Hits	75	Shared Neighborhood Hits	45
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PGFRB_HUMAN
NC score	0.092178 (rank : 739)	θ value	θ > 10 (rank : 1013)
Query Neighborhood Hits	600	Target Neighborhood Hits	962	Shared Neighborhood Hits	119
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PSG10_HUMAN
NC score	0.091989 (rank : 740)	θ value	θ > 10 (rank : 1030)
Query Neighborhood Hits	600	Target Neighborhood Hits	227	Shared Neighborhood Hits	69
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

PTN7_HUMAN
NC score	0.091763 (rank : 741)	θ value	θ > 10 (rank : 1068)
Query Neighborhood Hits	600	Target Neighborhood Hits	75	Shared Neighborhood Hits	21
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
NC score	0.091757 (rank : 742)	θ value	θ > 10 (rank : 1069)
Query Neighborhood Hits	600	Target Neighborhood Hits	71	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

ADA11_HUMAN
NC score	0.091713 (rank : 743)	θ value	0.62314 (rank : 401)
Query Neighborhood Hits	600	Target Neighborhood Hits	259	Shared Neighborhood Hits	153
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

PTN18_MOUSE
NC score	0.091499 (rank : 744)	θ value	θ > 10 (rank : 1052)
Query Neighborhood Hits	600	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

IRPL1_MOUSE
NC score	0.091401 (rank : 745)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	600	Target Neighborhood Hits	186	Shared Neighborhood Hits	67
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

PGH1_MOUSE
NC score	0.091379 (rank : 746)	θ value	θ > 10 (rank : 1018)
Query Neighborhood Hits	600	Target Neighborhood Hits	100	Shared Neighborhood Hits	69
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

LRP5_HUMAN
NC score	0.091324 (rank : 747)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	600	Target Neighborhood Hits	224	Shared Neighborhood Hits	90
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

IGS21_MOUSE
NC score	0.091307 (rank : 748)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	600	Target Neighborhood Hits	118	Shared Neighborhood Hits	45
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

CXAR_MOUSE
NC score	0.091283 (rank : 749)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	600	Target Neighborhood Hits	250	Shared Neighborhood Hits	60
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

PTN9_MOUSE
NC score	0.091198 (rank : 750)	θ value	θ > 10 (rank : 1071)
Query Neighborhood Hits	600	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN5_MOUSE
NC score	0.091023 (rank : 751)	θ value	θ > 10 (rank : 1065)
Query Neighborhood Hits	600	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.090977 (rank : 752)	θ value	θ > 10 (rank : 1064)
Query Neighborhood Hits	600	Target Neighborhood Hits	80	Shared Neighborhood Hits	21
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN9_HUMAN
NC score	0.090901 (rank : 753)	θ value	θ > 10 (rank : 1070)
Query Neighborhood Hits	600	Target Neighborhood Hits	79	Shared Neighborhood Hits	21
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPRR_MOUSE
NC score	0.090885 (rank : 754)	θ value	6.88961 (rank : 556)
Query Neighborhood Hits	600	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

KR241_HUMAN
NC score	0.090871 (rank : 755)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	600	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KR122_HUMAN
NC score	0.090753 (rank : 756)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	600	Target Neighborhood Hits	97	Shared Neighborhood Hits	45
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

MOX2R_MOUSE
NC score	0.090701 (rank : 757)	θ value	θ > 10 (rank : 955)
Query Neighborhood Hits	600	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

ADA11_MOUSE
NC score	0.090533 (rank : 758)	θ value	8.99809 (rank : 571)
Query Neighborhood Hits	600	Target Neighborhood Hits	263	Shared Neighborhood Hits	153
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

PSG2_HUMAN
NC score	0.090384 (rank : 759)	θ value	θ > 10 (rank : 1033)
Query Neighborhood Hits	600	Target Neighborhood Hits	229	Shared Neighborhood Hits	70
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

CORIN_MOUSE
NC score	0.090334 (rank : 760)	θ value	8.99809 (rank : 579)
Query Neighborhood Hits	600	Target Neighborhood Hits	451	Shared Neighborhood Hits	152
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

TNR19_HUMAN
NC score	0.090164 (rank : 761)	θ value	5.27518 (rank : 535)
Query Neighborhood Hits	600	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

PTN2_HUMAN
NC score	0.089973 (rank : 762)	θ value	θ > 10 (rank : 1061)
Query Neighborhood Hits	600	Target Neighborhood Hits	92	Shared Neighborhood Hits	22
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTPRR_HUMAN
NC score	0.089899 (rank : 763)	θ value	θ > 10 (rank : 1082)
Query Neighborhood Hits	600	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

LCE5A_HUMAN
NC score	0.089795 (rank : 764)	θ value	4.03905 (rank : 498)
Query Neighborhood Hits	600	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

UNC5C_HUMAN
NC score	0.089727 (rank : 765)	θ value	θ > 10 (rank : 1178)
Query Neighborhood Hits	600	Target Neighborhood Hits	226	Shared Neighborhood Hits	78
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
NC score	0.089670 (rank : 766)	θ value	θ > 10 (rank : 1179)
Query Neighborhood Hits	600	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

TNR6_MOUSE
NC score	0.089458 (rank : 767)	θ value	θ > 10 (rank : 1158)
Query Neighborhood Hits	600	Target Neighborhood Hits	99	Shared Neighborhood Hits	66
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

PTN2_MOUSE
NC score	0.089373 (rank : 768)	θ value	θ > 10 (rank : 1062)
Query Neighborhood Hits	600	Target Neighborhood Hits	107	Shared Neighborhood Hits	21
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

CO8B_MOUSE
NC score	0.089282 (rank : 769)	θ value	8.99809 (rank : 578)
Query Neighborhood Hits	600	Target Neighborhood Hits	224	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

RSPO4_HUMAN
NC score	0.089063 (rank : 770)	θ value	θ > 10 (rank : 1107)
Query Neighborhood Hits	600	Target Neighborhood Hits	110	Shared Neighborhood Hits	63
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

PTN22_HUMAN
NC score	0.088940 (rank : 771)	θ value	θ > 10 (rank : 1057)
Query Neighborhood Hits	600	Target Neighborhood Hits	109	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN1_HUMAN
NC score	0.088893 (rank : 772)	θ value	θ > 10 (rank : 1053)
Query Neighborhood Hits	600	Target Neighborhood Hits	84	Shared Neighborhood Hits	21
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PERT_HUMAN
NC score	0.088879 (rank : 773)	θ value	θ > 10 (rank : 1006)
Query Neighborhood Hits	600	Target Neighborhood Hits	221	Shared Neighborhood Hits	100
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PTPR2_MOUSE
NC score	0.088823 (rank : 774)	θ value	θ > 10 (rank : 1073)
Query Neighborhood Hits	600	Target Neighborhood Hits	120	Shared Neighborhood Hits	23
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTN1_MOUSE
NC score	0.088815 (rank : 775)	θ value	θ > 10 (rank : 1054)
Query Neighborhood Hits	600	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTPR2_HUMAN
NC score	0.088614 (rank : 776)	θ value	θ > 10 (rank : 1072)
Query Neighborhood Hits	600	Target Neighborhood Hits	103	Shared Neighborhood Hits	23
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

CSF1R_HUMAN
NC score	0.088583 (rank : 777)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	600	Target Neighborhood Hits	943	Shared Neighborhood Hits	110
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

PTN12_HUMAN
NC score	0.088493 (rank : 778)	θ value	θ > 10 (rank : 1045)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	24
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTPRN_HUMAN
NC score	0.088380 (rank : 779)	θ value	θ > 10 (rank : 1080)
Query Neighborhood Hits	600	Target Neighborhood Hits	156	Shared Neighborhood Hits	27
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

TNR1A_MOUSE
NC score	0.088152 (rank : 780)	θ value	1.81305 (rank : 459)
Query Neighborhood Hits	600	Target Neighborhood Hits	131	Shared Neighborhood Hits	66
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

LRRN3_MOUSE
NC score	0.088059 (rank : 781)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	600	Target Neighborhood Hits	455	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

UNC5B_HUMAN
NC score	0.087813 (rank : 782)	θ value	θ > 10 (rank : 1176)
Query Neighborhood Hits	600	Target Neighborhood Hits	225	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

ERBB3_HUMAN
NC score	0.087766 (rank : 783)	θ value	0.47712 (rank : 397)
Query Neighborhood Hits	600	Target Neighborhood Hits	918	Shared Neighborhood Hits	121
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

TNR1B_HUMAN
NC score	0.087737 (rank : 784)	θ value	8.99809 (rank : 596)
Query Neighborhood Hits	600	Target Neighborhood Hits	127	Shared Neighborhood Hits	71
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

SMDF_HUMAN
NC score	0.087654 (rank : 785)	θ value	θ > 10 (rank : 1118)
Query Neighborhood Hits	600	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

PTPRN_MOUSE
NC score	0.087477 (rank : 786)	θ value	θ > 10 (rank : 1081)
Query Neighborhood Hits	600	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

SIGL8_HUMAN
NC score	0.087453 (rank : 787)	θ value	θ > 10 (rank : 1117)
Query Neighborhood Hits	600	Target Neighborhood Hits	252	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

ESAM_MOUSE
NC score	0.087338 (rank : 788)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	600	Target Neighborhood Hits	222	Shared Neighborhood Hits	62
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

SIGL5_HUMAN
NC score	0.087232 (rank : 789)	θ value	θ > 10 (rank : 1114)
Query Neighborhood Hits	600	Target Neighborhood Hits	246	Shared Neighborhood Hits	69
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

PTN18_HUMAN
NC score	0.087203 (rank : 790)	θ value	θ > 10 (rank : 1051)
Query Neighborhood Hits	600	Target Neighborhood Hits	73	Shared Neighborhood Hits	21
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN12_MOUSE
NC score	0.087200 (rank : 791)	θ value	θ > 10 (rank : 1046)
Query Neighborhood Hits	600	Target Neighborhood Hits	123	Shared Neighborhood Hits	23
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

TR19L_MOUSE
NC score	0.087184 (rank : 792)	θ value	θ > 10 (rank : 1166)
Query Neighborhood Hits	600	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

UNC5B_MOUSE
NC score	0.087169 (rank : 793)	θ value	θ > 10 (rank : 1177)
Query Neighborhood Hits	600	Target Neighborhood Hits	226	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

PROC_HUMAN
NC score	0.086578 (rank : 794)	θ value	θ > 10 (rank : 1026)
Query Neighborhood Hits	600	Target Neighborhood Hits	406	Shared Neighborhood Hits	157
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PTN22_MOUSE
NC score	0.086329 (rank : 795)	θ value	θ > 10 (rank : 1058)
Query Neighborhood Hits	600	Target Neighborhood Hits	179	Shared Neighborhood Hits	25
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PSG9_HUMAN
NC score	0.085770 (rank : 796)	θ value	θ > 10 (rank : 1040)
Query Neighborhood Hits	600	Target Neighborhood Hits	221	Shared Neighborhood Hits	68
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

IRPL1_HUMAN
NC score	0.085701 (rank : 797)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	600	Target Neighborhood Hits	196	Shared Neighborhood Hits	66
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

ADA15_MOUSE
NC score	0.085628 (rank : 798)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	600	Target Neighborhood Hits	324	Shared Neighborhood Hits	158
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

TNR5_HUMAN
NC score	0.085277 (rank : 799)	θ value	θ > 10 (rank : 1155)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	70
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

PECA1_HUMAN
NC score	0.085099 (rank : 800)	θ value	θ > 10 (rank : 1004)
Query Neighborhood Hits	600	Target Neighborhood Hits	178	Shared Neighborhood Hits	57
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

I27RA_MOUSE
NC score	0.084994 (rank : 801)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	600	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

UROL1_HUMAN
NC score	0.084881 (rank : 802)	θ value	θ > 10 (rank : 1182)
Query Neighborhood Hits	600	Target Neighborhood Hits	213	Shared Neighborhood Hits	97
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ADA15_HUMAN
NC score	0.084647 (rank : 803)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	600	Target Neighborhood Hits	288	Shared Neighborhood Hits	143
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

UNC5A_MOUSE
NC score	0.084637 (rank : 804)	θ value	θ > 10 (rank : 1175)
Query Neighborhood Hits	600	Target Neighborhood Hits	203	Shared Neighborhood Hits	76
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

APR3_MOUSE
NC score	0.084557 (rank : 805)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	600	Target Neighborhood Hits	61	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

EMR4_MOUSE
NC score	0.084414 (rank : 806)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	600	Target Neighborhood Hits	191	Shared Neighborhood Hits	77
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

TR19L_HUMAN
NC score	0.084397 (rank : 807)	θ value	θ > 10 (rank : 1165)
Query Neighborhood Hits	600	Target Neighborhood Hits	99	Shared Neighborhood Hits	53
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

LRRN5_HUMAN
NC score	0.084058 (rank : 808)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	600	Target Neighborhood Hits	493	Shared Neighborhood Hits	91
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

RSPO4_MOUSE
NC score	0.083476 (rank : 809)	θ value	θ > 10 (rank : 1108)
Query Neighborhood Hits	600	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

PDL1_HUMAN
NC score	0.082763 (rank : 810)	θ value	θ > 10 (rank : 1001)
Query Neighborhood Hits	600	Target Neighborhood Hits	195	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

LRC24_HUMAN
NC score	0.082651 (rank : 811)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	600	Target Neighborhood Hits	404	Shared Neighborhood Hits	83
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRP12_HUMAN
NC score	0.082544 (rank : 812)	θ value	1.06291 (rank : 423)
Query Neighborhood Hits	600	Target Neighborhood Hits	205	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

PTN6_HUMAN
NC score	0.082433 (rank : 813)	θ value	θ > 10 (rank : 1066)
Query Neighborhood Hits	600	Target Neighborhood Hits	234	Shared Neighborhood Hits	22
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

CD320_HUMAN
NC score	0.082207 (rank : 814)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	600	Target Neighborhood Hits	103	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

ADAM8_HUMAN
NC score	0.082199 (rank : 815)	θ value	0.365318 (rank : 385)
Query Neighborhood Hits	600	Target Neighborhood Hits	327	Shared Neighborhood Hits	151
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

PTN6_MOUSE
NC score	0.082161 (rank : 816)	θ value	θ > 10 (rank : 1067)
Query Neighborhood Hits	600	Target Neighborhood Hits	225	Shared Neighborhood Hits	22
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

EMB_MOUSE
NC score	0.082076 (rank : 817)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	600	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

NTRK1_HUMAN
NC score	0.081944 (rank : 818)	θ value	θ > 10 (rank : 992)
Query Neighborhood Hits	600	Target Neighborhood Hits	1023	Shared Neighborhood Hits	115
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

ERBB4_HUMAN
NC score	0.081870 (rank : 819)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	600	Target Neighborhood Hits	910	Shared Neighborhood Hits	115
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

CHRD_MOUSE
NC score	0.081849 (rank : 820)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

PIGR_HUMAN
NC score	0.081813 (rank : 821)	θ value	θ > 10 (rank : 1022)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	52
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

PGH1_HUMAN
NC score	0.081156 (rank : 822)	θ value	θ > 10 (rank : 1017)
Query Neighborhood Hits	600	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PSG5_HUMAN
NC score	0.081102 (rank : 823)	θ value	θ > 10 (rank : 1036)
Query Neighborhood Hits	600	Target Neighborhood Hits	231	Shared Neighborhood Hits	71
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

ADAM8_MOUSE
NC score	0.081010 (rank : 824)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	600	Target Neighborhood Hits	326	Shared Neighborhood Hits	149
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

FA7_MOUSE
NC score	0.080877 (rank : 825)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	600	Target Neighborhood Hits	374	Shared Neighborhood Hits	135
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

MT1F_HUMAN
NC score	0.080481 (rank : 826)	θ value	θ > 10 (rank : 956)
Query Neighborhood Hits	600	Target Neighborhood Hits	73	Shared Neighborhood Hits	52
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

VASN_HUMAN
NC score	0.080423 (rank : 827)	θ value	θ > 10 (rank : 1184)
Query Neighborhood Hits	600	Target Neighborhood Hits	449	Shared Neighborhood Hits	115
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

TECTA_HUMAN
NC score	0.079842 (rank : 828)	θ value	θ > 10 (rank : 1135)
Query Neighborhood Hits	600	Target Neighborhood Hits	239	Shared Neighborhood Hits	119
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

PTN23_MOUSE
NC score	0.079669 (rank : 829)	θ value	θ > 10 (rank : 1060)
Query Neighborhood Hits	600	Target Neighborhood Hits	726	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN11_HUMAN
NC score	0.079557 (rank : 830)	θ value	θ > 10 (rank : 1043)
Query Neighborhood Hits	600	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.079538 (rank : 831)	θ value	θ > 10 (rank : 1044)
Query Neighborhood Hits	600	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

MATN1_MOUSE
NC score	0.079428 (rank : 832)	θ value	θ > 10 (rank : 938)
Query Neighborhood Hits	600	Target Neighborhood Hits	186	Shared Neighborhood Hits	77
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

ERBB3_MOUSE
NC score	0.079088 (rank : 833)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	600	Target Neighborhood Hits	898	Shared Neighborhood Hits	105
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

SIG12_HUMAN
NC score	0.078964 (rank : 834)	θ value	θ > 10 (rank : 1113)
Query Neighborhood Hits	600	Target Neighborhood Hits	245	Shared Neighborhood Hits	76
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

MATN1_HUMAN
NC score	0.078890 (rank : 835)	θ value	θ > 10 (rank : 937)
Query Neighborhood Hits	600	Target Neighborhood Hits	191	Shared Neighborhood Hits	80
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

PGFRL_HUMAN
NC score	0.078867 (rank : 836)	θ value	θ > 10 (rank : 1015)
Query Neighborhood Hits	600	Target Neighborhood Hits	115	Shared Neighborhood Hits	52
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

PERT_MOUSE
NC score	0.078837 (rank : 837)	θ value	θ > 10 (rank : 1007)
Query Neighborhood Hits	600	Target Neighborhood Hits	221	Shared Neighborhood Hits	96
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PIGR_MOUSE
NC score	0.078225 (rank : 838)	θ value	θ > 10 (rank : 1023)
Query Neighborhood Hits	600	Target Neighborhood Hits	214	Shared Neighborhood Hits	54
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

MT2_HUMAN
NC score	0.078008 (rank : 839)	θ value	8.99809 (rank : 587)
Query Neighborhood Hits	600	Target Neighborhood Hits	69	Shared Neighborhood Hits	49
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

PTN23_HUMAN
NC score	0.077971 (rank : 840)	θ value	θ > 10 (rank : 1059)
Query Neighborhood Hits	600	Target Neighborhood Hits	646	Shared Neighborhood Hits	45
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

TR10B_MOUSE
NC score	0.077763 (rank : 841)	θ value	θ > 10 (rank : 1162)
Query Neighborhood Hits	600	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

LRP12_MOUSE
NC score	0.077749 (rank : 842)	θ value	5.27518 (rank : 519)
Query Neighborhood Hits	600	Target Neighborhood Hits	180	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

RSPO3_HUMAN
NC score	0.077565 (rank : 843)	θ value	θ > 10 (rank : 1105)
Query Neighborhood Hits	600	Target Neighborhood Hits	128	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

EGFR_MOUSE
NC score	0.077172 (rank : 844)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	600	Target Neighborhood Hits	927	Shared Neighborhood Hits	121
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EGFR_HUMAN
NC score	0.076988 (rank : 845)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	600	Target Neighborhood Hits	939	Shared Neighborhood Hits	127
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

ILRL2_MOUSE
NC score	0.076515 (rank : 846)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	600	Target Neighborhood Hits	158	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

MT1I_HUMAN
NC score	0.076229 (rank : 847)	θ value	6.88961 (rank : 554)
Query Neighborhood Hits	600	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

ERBB2_HUMAN
NC score	0.076165 (rank : 848)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	600	Target Neighborhood Hits	1073	Shared Neighborhood Hits	117
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

MEP1A_MOUSE
NC score	0.075911 (rank : 849)	θ value	θ > 10 (rank : 944)
Query Neighborhood Hits	600	Target Neighborhood Hits	166	Shared Neighborhood Hits	94
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

PDL2_MOUSE
NC score	0.075903 (rank : 850)	θ value	θ > 10 (rank : 1003)
Query Neighborhood Hits	600	Target Neighborhood Hits	116	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

I11RB_MOUSE
NC score	0.075576 (rank : 851)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	600	Target Neighborhood Hits	101	Shared Neighborhood Hits	51
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

VASN_MOUSE
NC score	0.075186 (rank : 852)	θ value	θ > 10 (rank : 1185)
Query Neighborhood Hits	600	Target Neighborhood Hits	426	Shared Neighborhood Hits	110
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ADA23_HUMAN
NC score	0.074369 (rank : 853)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	600	Target Neighborhood Hits	235	Shared Neighborhood Hits	134
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

WFDC3_HUMAN
NC score	0.074355 (rank : 854)	θ value	θ > 10 (rank : 1200)
Query Neighborhood Hits	600	Target Neighborhood Hits	138	Shared Neighborhood Hits	57
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

PECA1_MOUSE
NC score	0.073617 (rank : 855)	θ value	θ > 10 (rank : 1005)
Query Neighborhood Hits	600	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

CHRD_HUMAN
NC score	0.073409 (rank : 856)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

ERBB2_MOUSE
NC score	0.073363 (rank : 857)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	600	Target Neighborhood Hits	918	Shared Neighborhood Hits	104
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

IL6RA_MOUSE
NC score	0.073314 (rank : 858)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	600	Target Neighborhood Hits	104	Shared Neighborhood Hits	47
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

NRG4_HUMAN
NC score	0.073055 (rank : 859)	θ value	θ > 10 (rank : 985)
Query Neighborhood Hits	600	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PVRL3_MOUSE
NC score	0.072860 (rank : 860)	θ value	θ > 10 (rank : 1087)
Query Neighborhood Hits	600	Target Neighborhood Hits	212	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

TNR6_HUMAN
NC score	0.072853 (rank : 861)	θ value	θ > 10 (rank : 1157)
Query Neighborhood Hits	600	Target Neighborhood Hits	95	Shared Neighborhood Hits	63
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

LRC24_MOUSE
NC score	0.072649 (rank : 862)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	600	Target Neighborhood Hits	387	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

IL1R1_MOUSE
NC score	0.072634 (rank : 863)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	600	Target Neighborhood Hits	142	Shared Neighborhood Hits	58
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

RYK_HUMAN
NC score	0.072543 (rank : 864)	θ value	θ > 10 (rank : 1109)
Query Neighborhood Hits	600	Target Neighborhood Hits	701	Shared Neighborhood Hits	53
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

FLT3_MOUSE
NC score	0.072526 (rank : 865)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	600	Target Neighborhood Hits	847	Shared Neighborhood Hits	86
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

APR3_HUMAN
NC score	0.072469 (rank : 866)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	600	Target Neighborhood Hits	50	Shared Neighborhood Hits	43
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

SIGL6_HUMAN
NC score	0.072361 (rank : 867)	θ value	θ > 10 (rank : 1116)
Query Neighborhood Hits	600	Target Neighborhood Hits	233	Shared Neighborhood Hits	72
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

DDR1_HUMAN
NC score	0.072306 (rank : 868)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	600	Target Neighborhood Hits	819	Shared Neighborhood Hits	64
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR2_HUMAN
NC score	0.071989 (rank : 869)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	600	Target Neighborhood Hits	818	Shared Neighborhood Hits	62
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

PTN3_HUMAN
NC score	0.071375 (rank : 870)	θ value	5.27518 (rank : 529)
Query Neighborhood Hits	600	Target Neighborhood Hits	258	Shared Neighborhood Hits	28
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

DDR2_MOUSE
NC score	0.071335 (rank : 871)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	600	Target Neighborhood Hits	813	Shared Neighborhood Hits	63
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

RYK_MOUSE
NC score	0.071330 (rank : 872)	θ value	θ > 10 (rank : 1110)
Query Neighborhood Hits	600	Target Neighborhood Hits	715	Shared Neighborhood Hits	53
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

DDR1_MOUSE
NC score	0.071141 (rank : 873)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	600	Target Neighborhood Hits	818	Shared Neighborhood Hits	64
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

RSPO3_MOUSE
NC score	0.071090 (rank : 874)	θ value	θ > 10 (rank : 1106)
Query Neighborhood Hits	600	Target Neighborhood Hits	120	Shared Neighborhood Hits	58
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

ADA23_MOUSE
NC score	0.071022 (rank : 875)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	600	Target Neighborhood Hits	245	Shared Neighborhood Hits	144
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

FST_MOUSE
NC score	0.070989 (rank : 876)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	600	Target Neighborhood Hits	146	Shared Neighborhood Hits	68
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

PTN14_HUMAN
NC score	0.070916 (rank : 877)	θ value	θ > 10 (rank : 1049)
Query Neighborhood Hits	600	Target Neighborhood Hits	163	Shared Neighborhood Hits	28
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

NRG4_MOUSE
NC score	0.070844 (rank : 878)	θ value	θ > 10 (rank : 986)
Query Neighborhood Hits	600	Target Neighborhood Hits	79	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

IL1R1_HUMAN
NC score	0.070842 (rank : 879)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	600	Target Neighborhood Hits	140	Shared Neighborhood Hits	54
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

LRC4B_MOUSE
NC score	0.070804 (rank : 880)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	600	Target Neighborhood Hits	484	Shared Neighborhood Hits	81
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

PTN14_MOUSE
NC score	0.070089 (rank : 881)	θ value	θ > 10 (rank : 1050)
Query Neighborhood Hits	600	Target Neighborhood Hits	142	Shared Neighborhood Hits	27
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

ZNFX1_MOUSE
NC score	0.070076 (rank : 882)	θ value	θ > 10 (rank : 1206)
Query Neighborhood Hits	600	Target Neighborhood Hits	407	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ADAM9_MOUSE
NC score	0.069989 (rank : 883)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	600	Target Neighborhood Hits	325	Shared Neighborhood Hits	150
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ILRL1_HUMAN
NC score	0.069733 (rank : 884)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	600	Target Neighborhood Hits	167	Shared Neighborhood Hits	53
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

LRC4B_HUMAN
NC score	0.069719 (rank : 885)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	600	Target Neighborhood Hits	479	Shared Neighborhood Hits	80
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

ALK_MOUSE
NC score	0.069631 (rank : 886)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	600	Target Neighborhood Hits	811	Shared Neighborhood Hits	73
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

PTN21_MOUSE
NC score	0.069591 (rank : 887)	θ value	θ > 10 (rank : 1056)
Query Neighborhood Hits	600	Target Neighborhood Hits	155	Shared Neighborhood Hits	28
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

I11RA_HUMAN
NC score	0.069572 (rank : 888)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	600	Target Neighborhood Hits	138	Shared Neighborhood Hits	54
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

PTN21_HUMAN
NC score	0.069329 (rank : 889)	θ value	θ > 10 (rank : 1055)
Query Neighborhood Hits	600	Target Neighborhood Hits	143	Shared Neighborhood Hits	26
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

LTK_MOUSE
NC score	0.069258 (rank : 890)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	600	Target Neighborhood Hits	770	Shared Neighborhood Hits	58
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LTK_HUMAN
NC score	0.069169 (rank : 891)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	600	Target Neighborhood Hits	774	Shared Neighborhood Hits	58
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

MEP1A_HUMAN
NC score	0.069121 (rank : 892)	θ value	θ > 10 (rank : 943)
Query Neighborhood Hits	600	Target Neighborhood Hits	162	Shared Neighborhood Hits	89
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

RSPO2_HUMAN
NC score	0.068974 (rank : 893)	θ value	θ > 10 (rank : 1103)
Query Neighborhood Hits	600	Target Neighborhood Hits	90	Shared Neighborhood Hits	44
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

ALK_HUMAN
NC score	0.068922 (rank : 894)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	600	Target Neighborhood Hits	795	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

CRAC1_MOUSE
NC score	0.068810 (rank : 895)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	600	Target Neighborhood Hits	112	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

ADA22_MOUSE
NC score	0.068773 (rank : 896)	θ value	1.81305 (rank : 439)
Query Neighborhood Hits	600	Target Neighborhood Hits	225	Shared Neighborhood Hits	121
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADA19_MOUSE
NC score	0.068536 (rank : 897)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	600	Target Neighborhood Hits	315	Shared Neighborhood Hits	149
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

NGL1_MOUSE
NC score	0.068057 (rank : 898)	θ value	θ > 10 (rank : 978)
Query Neighborhood Hits	600	Target Neighborhood Hits	512	Shared Neighborhood Hits	81
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_HUMAN
NC score	0.067964 (rank : 899)	θ value	θ > 10 (rank : 977)
Query Neighborhood Hits	600	Target Neighborhood Hits	511	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

ZNFX1_HUMAN
NC score	0.067902 (rank : 900)	θ value	θ > 10 (rank : 1205)
Query Neighborhood Hits	600	Target Neighborhood Hits	308	Shared Neighborhood Hits	84
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

I11RA_MOUSE
NC score	0.067866 (rank : 901)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	600	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

PVRL1_HUMAN
NC score	0.067568 (rank : 902)	θ value	θ > 10 (rank : 1083)
Query Neighborhood Hits	600	Target Neighborhood Hits	219	Shared Neighborhood Hits	47
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

EREG_HUMAN
NC score	0.067446 (rank : 903)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	600	Target Neighborhood Hits	73	Shared Neighborhood Hits	44
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

PTN4_HUMAN
NC score	0.067439 (rank : 904)	θ value	θ > 10 (rank : 1063)
Query Neighborhood Hits	600	Target Neighborhood Hits	303	Shared Neighborhood Hits	28
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

TR11B_MOUSE
NC score	0.067420 (rank : 905)	θ value	θ > 10 (rank : 1164)
Query Neighborhood Hits	600	Target Neighborhood Hits	95	Shared Neighborhood Hits	57
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

FST_HUMAN
NC score	0.067158 (rank : 906)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	600	Target Neighborhood Hits	129	Shared Neighborhood Hits	54
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

PVRL3_HUMAN
NC score	0.067140 (rank : 907)	θ value	θ > 10 (rank : 1086)
Query Neighborhood Hits	600	Target Neighborhood Hits	204	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

BMP1_MOUSE
NC score	0.067020 (rank : 908)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	101
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

RSPO2_MOUSE
NC score	0.066894 (rank : 909)	θ value	θ > 10 (rank : 1104)
Query Neighborhood Hits	600	Target Neighborhood Hits	88	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

CRAC1_HUMAN
NC score	0.066880 (rank : 910)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	600	Target Neighborhood Hits	111	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

TLL1_MOUSE
NC score	0.066606 (rank : 911)	θ value	θ > 10 (rank : 1143)
Query Neighborhood Hits	600	Target Neighborhood Hits	237	Shared Neighborhood Hits	98
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

BMP1_HUMAN
NC score	0.066474 (rank : 912)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	600	Target Neighborhood Hits	233	Shared Neighborhood Hits	100
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

ADA10_HUMAN
NC score	0.066148 (rank : 913)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	600	Target Neighborhood Hits	189	Shared Neighborhood Hits	96
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA33_HUMAN
NC score	0.066107 (rank : 914)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	600	Target Neighborhood Hits	264	Shared Neighborhood Hits	126
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA19_HUMAN
NC score	0.066097 (rank : 915)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	600	Target Neighborhood Hits	381	Shared Neighborhood Hits	140
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

TNR1A_HUMAN
NC score	0.065912 (rank : 916)	θ value	2.36792 (rank : 468)
Query Neighborhood Hits	600	Target Neighborhood Hits	121	Shared Neighborhood Hits	59
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

LRRC4_HUMAN
NC score	0.065748 (rank : 917)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	600	Target Neighborhood Hits	444	Shared Neighborhood Hits	81
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

PDL1_MOUSE
NC score	0.065158 (rank : 918)	θ value	θ > 10 (rank : 1002)
Query Neighborhood Hits	600	Target Neighborhood Hits	168	Shared Neighborhood Hits	54
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

TLL2_HUMAN
NC score	0.064979 (rank : 919)	θ value	θ > 10 (rank : 1144)
Query Neighborhood Hits	600	Target Neighborhood Hits	241	Shared Neighborhood Hits	105
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

JAML1_MOUSE
NC score	0.064839 (rank : 920)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	600	Target Neighborhood Hits	185	Shared Neighborhood Hits	42
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

TR10A_HUMAN
NC score	0.064311 (rank : 921)	θ value	0.0563607 (rank : 348)
Query Neighborhood Hits	600	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

KR124_HUMAN
NC score	0.064261 (rank : 922)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	600	Target Neighborhood Hits	124	Shared Neighborhood Hits	64
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

FLT3_HUMAN
NC score	0.063847 (rank : 923)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	600	Target Neighborhood Hits	843	Shared Neighborhood Hits	72
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

ADAM9_HUMAN
NC score	0.063673 (rank : 924)	θ value	4.03905 (rank : 494)
Query Neighborhood Hits	600	Target Neighborhood Hits	243	Shared Neighborhood Hits	131
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

TLL1_HUMAN
NC score	0.063571 (rank : 925)	θ value	θ > 10 (rank : 1142)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	95
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

GP116_HUMAN
NC score	0.063536 (rank : 926)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	600	Target Neighborhood Hits	167	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

LCE3B_HUMAN
NC score	0.063258 (rank : 927)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	600	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

CO9_MOUSE
NC score	0.063243 (rank : 928)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	600	Target Neighborhood Hits	153	Shared Neighborhood Hits	71
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

PAPPA_MOUSE
NC score	0.063155 (rank : 929)	θ value	θ > 10 (rank : 1000)
Query Neighborhood Hits	600	Target Neighborhood Hits	153	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

RET_MOUSE
NC score	0.062884 (rank : 930)	θ value	θ > 10 (rank : 1096)
Query Neighborhood Hits	600	Target Neighborhood Hits	884	Shared Neighborhood Hits	73
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

CLC14_MOUSE
NC score	0.062782 (rank : 931)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	600	Target Neighborhood Hits	120	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

PTN13_MOUSE
NC score	0.062665 (rank : 932)	θ value	θ > 10 (rank : 1048)
Query Neighborhood Hits	600	Target Neighborhood Hits	426	Shared Neighborhood Hits	28
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PVRL1_MOUSE
NC score	0.062434 (rank : 933)	θ value	θ > 10 (rank : 1084)
Query Neighborhood Hits	600	Target Neighborhood Hits	201	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

RET_HUMAN
NC score	0.062383 (rank : 934)	θ value	θ > 10 (rank : 1095)
Query Neighborhood Hits	600	Target Neighborhood Hits	873	Shared Neighborhood Hits	65
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

LAG3_MOUSE
NC score	0.062308 (rank : 935)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	600	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

CD79A_HUMAN
NC score	0.062219 (rank : 936)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CD276_MOUSE
NC score	0.062101 (rank : 937)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	600	Target Neighborhood Hits	243	Shared Neighborhood Hits	54
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

LAG3_HUMAN
NC score	0.062019 (rank : 938)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	600	Target Neighborhood Hits	129	Shared Neighborhood Hits	26
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

MT1M_HUMAN
NC score	0.061928 (rank : 939)	θ value	θ > 10 (rank : 959)
Query Neighborhood Hits	600	Target Neighborhood Hits	72	Shared Neighborhood Hits	46
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

PTN13_HUMAN
NC score	0.061860 (rank : 940)	θ value	θ > 10 (rank : 1047)
Query Neighborhood Hits	600	Target Neighborhood Hits	471	Shared Neighborhood Hits	30
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

CO9_HUMAN
NC score	0.061650 (rank : 941)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	600	Target Neighborhood Hits	147	Shared Neighborhood Hits	68
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

STYK1_MOUSE
NC score	0.061636 (rank : 942)	θ value	θ > 10 (rank : 1130)
Query Neighborhood Hits	600	Target Neighborhood Hits	779	Shared Neighborhood Hits	55
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

ADA22_HUMAN
NC score	0.061629 (rank : 943)	θ value	0.813845 (rank : 411)
Query Neighborhood Hits	600	Target Neighborhood Hits	211	Shared Neighborhood Hits	114
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

TNK1_HUMAN
NC score	0.061405 (rank : 944)	θ value	θ > 10 (rank : 1148)
Query Neighborhood Hits	600	Target Neighborhood Hits	815	Shared Neighborhood Hits	54
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

ADAM2_MOUSE
NC score	0.061332 (rank : 945)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	600	Target Neighborhood Hits	209	Shared Neighborhood Hits	116
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

SPR2D_MOUSE
NC score	0.061070 (rank : 946)	θ value	θ > 10 (rank : 1120)
Query Neighborhood Hits	600	Target Neighborhood Hits	61	Shared Neighborhood Hits	20
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

PAPPA_HUMAN
NC score	0.061049 (rank : 947)	θ value	5.27518 (rank : 527)
Query Neighborhood Hits	600	Target Neighborhood Hits	161	Shared Neighborhood Hits	57
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PVR_HUMAN
NC score	0.061040 (rank : 948)	θ value	θ > 10 (rank : 1088)
Query Neighborhood Hits	600	Target Neighborhood Hits	195	Shared Neighborhood Hits	47
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

CEAM7_HUMAN
NC score	0.060771 (rank : 949)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	600	Target Neighborhood Hits	170	Shared Neighborhood Hits	60
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

TLL2_MOUSE
NC score	0.060710 (rank : 950)	θ value	θ > 10 (rank : 1145)
Query Neighborhood Hits	600	Target Neighborhood Hits	240	Shared Neighborhood Hits	99
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CLC14_HUMAN
NC score	0.060585 (rank : 951)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	600	Target Neighborhood Hits	143	Shared Neighborhood Hits	65
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

HHLA2_HUMAN
NC score	0.060514 (rank : 952)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	600	Target Neighborhood Hits	140	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

ADA18_MOUSE
NC score	0.060459 (rank : 953)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	600	Target Neighborhood Hits	227	Shared Neighborhood Hits	124
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

FAK2_HUMAN
NC score	0.060195 (rank : 954)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	600	Target Neighborhood Hits	847	Shared Neighborhood Hits	54
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

PRLR_HUMAN
NC score	0.060145 (rank : 955)	θ value	θ > 10 (rank : 1024)
Query Neighborhood Hits	600	Target Neighborhood Hits	95	Shared Neighborhood Hits	43
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

CO8A_HUMAN
NC score	0.060054 (rank : 956)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	600	Target Neighborhood Hits	200	Shared Neighborhood Hits	85
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

TNK1_MOUSE
NC score	0.060029 (rank : 957)	θ value	θ > 10 (rank : 1149)
Query Neighborhood Hits	600	Target Neighborhood Hits	806	Shared Neighborhood Hits	56
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

ADA10_MOUSE
NC score	0.059948 (rank : 958)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	93
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

PGFRL_MOUSE
NC score	0.059911 (rank : 959)	θ value	θ > 10 (rank : 1016)
Query Neighborhood Hits	600	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

FAK2_MOUSE
NC score	0.059758 (rank : 960)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	600	Target Neighborhood Hits	851	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

PRLR_MOUSE
NC score	0.059752 (rank : 961)	θ value	θ > 10 (rank : 1025)
Query Neighborhood Hits	600	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

ADAM7_HUMAN
NC score	0.059666 (rank : 962)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	600	Target Neighborhood Hits	221	Shared Neighborhood Hits	125
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

FAK1_HUMAN
NC score	0.059613 (rank : 963)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	600	Target Neighborhood Hits	850	Shared Neighborhood Hits	55
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

GP128_MOUSE
NC score	0.059596 (rank : 964)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	600	Target Neighborhood Hits	141	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

DKK3_MOUSE
NC score	0.059520 (rank : 965)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	600	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

ADA33_MOUSE
NC score	0.059496 (rank : 966)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	600	Target Neighborhood Hits	231	Shared Neighborhood Hits	126
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

FAK1_MOUSE
NC score	0.059490 (rank : 967)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	600	Target Neighborhood Hits	850	Shared Neighborhood Hits	55
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

STYK1_HUMAN
NC score	0.059379 (rank : 968)	θ value	θ > 10 (rank : 1129)
Query Neighborhood Hits	600	Target Neighborhood Hits	786	Shared Neighborhood Hits	57
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

TRIO_HUMAN
NC score	0.059353 (rank : 969)	θ value	θ > 10 (rank : 1171)
Query Neighborhood Hits	600	Target Neighborhood Hits	1580	Shared Neighborhood Hits	132
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TR11B_HUMAN
NC score	0.059346 (rank : 970)	θ value	θ > 10 (rank : 1163)
Query Neighborhood Hits	600	Target Neighborhood Hits	92	Shared Neighborhood Hits	55
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

MET_MOUSE
NC score	0.059266 (rank : 971)	θ value	θ > 10 (rank : 947)
Query Neighborhood Hits	600	Target Neighborhood Hits	844	Shared Neighborhood Hits	58
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

ACK1_MOUSE
NC score	0.059195 (rank : 972)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	600	Target Neighborhood Hits	1080	Shared Neighborhood Hits	62
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

CO8B_HUMAN
NC score	0.059174 (rank : 973)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	600	Target Neighborhood Hits	199	Shared Neighborhood Hits	75
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

ILK2_HUMAN
NC score	0.059014 (rank : 974)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	600	Target Neighborhood Hits	848	Shared Neighborhood Hits	63
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ILK_MOUSE
NC score	0.059013 (rank : 975)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	600	Target Neighborhood Hits	858	Shared Neighborhood Hits	63
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ILK1_HUMAN
NC score	0.058972 (rank : 976)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	600	Target Neighborhood Hits	857	Shared Neighborhood Hits	63
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

MET_HUMAN
NC score	0.058946 (rank : 977)	θ value	θ > 10 (rank : 946)
Query Neighborhood Hits	600	Target Neighborhood Hits	831	Shared Neighborhood Hits	54
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

RON_MOUSE
NC score	0.058842 (rank : 978)	θ value	θ > 10 (rank : 1098)
Query Neighborhood Hits	600	Target Neighborhood Hits	836	Shared Neighborhood Hits	59
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ACK1_HUMAN
NC score	0.058620 (rank : 979)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	600	Target Neighborhood Hits	1140	Shared Neighborhood Hits	64
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

DKK3_HUMAN
NC score	0.058182 (rank : 980)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	600	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

ZAP70_HUMAN
NC score	0.057814 (rank : 981)	θ value	θ > 10 (rank : 1203)
Query Neighborhood Hits	600	Target Neighborhood Hits	893	Shared Neighborhood Hits	54
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

SPR2H_MOUSE
NC score	0.057795 (rank : 982)	θ value	θ > 10 (rank : 1122)
Query Neighborhood Hits	600	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

ZAP70_MOUSE
NC score	0.057700 (rank : 983)	θ value	θ > 10 (rank : 1204)
Query Neighborhood Hits	600	Target Neighborhood Hits	905	Shared Neighborhood Hits	55
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ASTN_MOUSE
NC score	0.057646 (rank : 984)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	600	Target Neighborhood Hits	98	Shared Neighborhood Hits	51
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ST14_HUMAN
NC score	0.057596 (rank : 985)	θ value	θ > 10 (rank : 1127)
Query Neighborhood Hits	600	Target Neighborhood Hits	409	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

RON_HUMAN
NC score	0.057417 (rank : 986)	θ value	θ > 10 (rank : 1097)
Query Neighborhood Hits	600	Target Neighborhood Hits	842	Shared Neighborhood Hits	59
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

AATK_MOUSE
NC score	0.057281 (rank : 987)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	600	Target Neighborhood Hits	942	Shared Neighborhood Hits	61
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

KSYK_MOUSE
NC score	0.056461 (rank : 988)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	600	Target Neighborhood Hits	944	Shared Neighborhood Hits	57
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_HUMAN
NC score	0.056415 (rank : 989)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	600	Target Neighborhood Hits	901	Shared Neighborhood Hits	54
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LRRC4_MOUSE
NC score	0.056408 (rank : 990)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	600	Target Neighborhood Hits	412	Shared Neighborhood Hits	75
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

GP128_HUMAN
NC score	0.055932 (rank : 991)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	600	Target Neighborhood Hits	135	Shared Neighborhood Hits	37
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

TNR21_MOUSE
NC score	0.055924 (rank : 992)	θ value	θ > 10 (rank : 1152)
Query Neighborhood Hits	600	Target Neighborhood Hits	108	Shared Neighborhood Hits	60
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TRI42_HUMAN
NC score	0.055810 (rank : 993)	θ value	θ > 10 (rank : 1169)
Query Neighborhood Hits	600	Target Neighborhood Hits	283	Shared Neighborhood Hits	81
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

FCGR1_HUMAN
NC score	0.055573 (rank : 994)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	600	Target Neighborhood Hits	145	Shared Neighborhood Hits	45
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

THYG_HUMAN
NC score	0.055432 (rank : 995)	θ value	3.0926 (rank : 485)
Query Neighborhood Hits	600	Target Neighborhood Hits	154	Shared Neighborhood Hits	82
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

ASTN_HUMAN
NC score	0.055287 (rank : 996)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	600	Target Neighborhood Hits	105	Shared Neighborhood Hits	51
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

FES_HUMAN
NC score	0.055261 (rank : 997)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	600	Target Neighborhood Hits	978	Shared Neighborhood Hits	56
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
NC score	0.055165 (rank : 998)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	600	Target Neighborhood Hits	980	Shared Neighborhood Hits	54
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

AATK_HUMAN
NC score	0.055142 (rank : 999)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	600	Target Neighborhood Hits	1243	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

TNR1B_MOUSE
NC score	0.055039 (rank : 1000)	θ value	θ > 10 (rank : 1151)
Query Neighborhood Hits	600	Target Neighborhood Hits	123	Shared Neighborhood Hits	58
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

ST14_MOUSE
NC score	0.054871 (rank : 1001)	θ value	θ > 10 (rank : 1128)
Query Neighborhood Hits	600	Target Neighborhood Hits	419	Shared Neighborhood Hits	128
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

IL6RA_HUMAN
NC score	0.054787 (rank : 1002)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	600	Target Neighborhood Hits	96	Shared Neighborhood Hits	38
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

SRMS_HUMAN
NC score	0.054554 (rank : 1003)	θ value	θ > 10 (rank : 1125)
Query Neighborhood Hits	600	Target Neighborhood Hits	946	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

FER_HUMAN
NC score	0.054497 (rank : 1004)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	600	Target Neighborhood Hits	1278	Shared Neighborhood Hits	60
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

TRI42_MOUSE
NC score	0.054452 (rank : 1005)	θ value	θ > 10 (rank : 1170)
Query Neighborhood Hits	600	Target Neighborhood Hits	316	Shared Neighborhood Hits	88
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

FCN1_MOUSE
NC score	0.054398 (rank : 1006)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	600	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

MEP1B_MOUSE
NC score	0.054351 (rank : 1007)	θ value	θ > 10 (rank : 945)
Query Neighborhood Hits	600	Target Neighborhood Hits	127	Shared Neighborhood Hits	71
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

ADA17_HUMAN
NC score	0.054128 (rank : 1008)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	600	Target Neighborhood Hits	223	Shared Neighborhood Hits	101
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA28_HUMAN
NC score	0.054124 (rank : 1009)	θ value	1.06291 (rank : 420)
Query Neighborhood Hits	600	Target Neighborhood Hits	244	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

GLPC_HUMAN
NC score	0.054123 (rank : 1010)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	600	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	P04921, Q92642	Gene names	GYPC, GPC
Domain Architecture
Description	Glycophorin C (PAS-2') (Glycoprotein beta) (GLPC) (Glycoconnectin) (Sialoglycoprotein D) (Glycophorin D) (GPD) (CD236 antigen).

CYR61_MOUSE
NC score	0.054060 (rank : 1011)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	600	Target Neighborhood Hits	156	Shared Neighborhood Hits	60
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

MATK_HUMAN
NC score	0.054023 (rank : 1012)	θ value	θ > 10 (rank : 935)
Query Neighborhood Hits	600	Target Neighborhood Hits	954	Shared Neighborhood Hits	54
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

IL27B_MOUSE
NC score	0.053874 (rank : 1013)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	600	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

FCN1_HUMAN
NC score	0.053769 (rank : 1014)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	600	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	O00602, Q92596	Gene names	FCN1
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

SPY1_MOUSE
NC score	0.053694 (rank : 1015)	θ value	0.47712 (rank : 400)
Query Neighborhood Hits	600	Target Neighborhood Hits	57	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

FCN3_HUMAN
NC score	0.053679 (rank : 1016)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	600	Target Neighborhood Hits	125	Shared Neighborhood Hits	14
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

MATK_MOUSE
NC score	0.053658 (rank : 1017)	θ value	θ > 10 (rank : 936)
Query Neighborhood Hits	600	Target Neighborhood Hits	952	Shared Neighborhood Hits	54
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

SRMS_MOUSE
NC score	0.053642 (rank : 1018)	θ value	θ > 10 (rank : 1126)
Query Neighborhood Hits	600	Target Neighborhood Hits	964	Shared Neighborhood Hits	54
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

TXK_MOUSE
NC score	0.053637 (rank : 1019)	θ value	θ > 10 (rank : 1173)
Query Neighborhood Hits	600	Target Neighborhood Hits	980	Shared Neighborhood Hits	56
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

FCN2_HUMAN
NC score	0.053571 (rank : 1020)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	600	Target Neighborhood Hits	122	Shared Neighborhood Hits	14
SwissProt Accessions	Q15485, Q9UC57	Gene names	FCN2
Domain Architecture
Description	Ficolin-2 precursor (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin B) (Serum lectin p35) (EBP-37) (Hucolin) (L- Ficolin).

CYR61_HUMAN
NC score	0.053566 (rank : 1021)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	600	Target Neighborhood Hits	159	Shared Neighborhood Hits	61
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

FCERA_HUMAN
NC score	0.053471 (rank : 1022)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	600	Target Neighborhood Hits	150	Shared Neighborhood Hits	44
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

TNR18_HUMAN
NC score	0.053440 (rank : 1023)	θ value	θ > 10 (rank : 1150)
Query Neighborhood Hits	600	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TPA_MOUSE
NC score	0.053355 (rank : 1024)	θ value	θ > 10 (rank : 1161)
Query Neighborhood Hits	600	Target Neighborhood Hits	335	Shared Neighborhood Hits	113
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

SPR2G_MOUSE
NC score	0.053117 (rank : 1025)	θ value	θ > 10 (rank : 1121)
Query Neighborhood Hits	600	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

TXK_HUMAN
NC score	0.053041 (rank : 1026)	θ value	θ > 10 (rank : 1172)
Query Neighborhood Hits	600	Target Neighborhood Hits	971	Shared Neighborhood Hits	56
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

ADA28_MOUSE
NC score	0.053013 (rank : 1027)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	600	Target Neighborhood Hits	241	Shared Neighborhood Hits	121
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

BMX_MOUSE
NC score	0.052879 (rank : 1028)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	600	Target Neighborhood Hits	912	Shared Neighborhood Hits	54
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

HCK_MOUSE
NC score	0.052842 (rank : 1029)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	600	Target Neighborhood Hits	1029	Shared Neighborhood Hits	55
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

LCK_HUMAN
NC score	0.052785 (rank : 1030)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	600	Target Neighborhood Hits	987	Shared Neighborhood Hits	57
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

ITK_MOUSE
NC score	0.052651 (rank : 1031)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	600	Target Neighborhood Hits	985	Shared Neighborhood Hits	57
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

LCK_MOUSE
NC score	0.052583 (rank : 1032)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	600	Target Neighborhood Hits	981	Shared Neighborhood Hits	54
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

BLK_MOUSE
NC score	0.052569 (rank : 1033)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	600	Target Neighborhood Hits	992	Shared Neighborhood Hits	55
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

HCK_HUMAN
NC score	0.052562 (rank : 1034)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	600	Target Neighborhood Hits	1035	Shared Neighborhood Hits	57
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

ITK_HUMAN
NC score	0.052501 (rank : 1035)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	600	Target Neighborhood Hits	1016	Shared Neighborhood Hits	57
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

BMX_HUMAN
NC score	0.052423 (rank : 1036)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	600	Target Neighborhood Hits	942	Shared Neighborhood Hits	55
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BTK_MOUSE
NC score	0.052331 (rank : 1037)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	600	Target Neighborhood Hits	1017	Shared Neighborhood Hits	58
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

BTK_HUMAN
NC score	0.052284 (rank : 1038)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	600	Target Neighborhood Hits	1026	Shared Neighborhood Hits	58
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

TEC_HUMAN
NC score	0.052167 (rank : 1039)	θ value	θ > 10 (rank : 1137)
Query Neighborhood Hits	600	Target Neighborhood Hits	1006	Shared Neighborhood Hits	55
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

CO8A_MOUSE
NC score	0.052053 (rank : 1040)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	600	Target Neighborhood Hits	182	Shared Neighborhood Hits	67
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

ABL1_MOUSE
NC score	0.052008 (rank : 1041)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	600	Target Neighborhood Hits	1178	Shared Neighborhood Hits	64
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

YES_HUMAN
NC score	0.051987 (rank : 1042)	θ value	θ > 10 (rank : 1201)
Query Neighborhood Hits	600	Target Neighborhood Hits	1059	Shared Neighborhood Hits	60
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

TEC_MOUSE
NC score	0.051961 (rank : 1043)	θ value	θ > 10 (rank : 1138)
Query Neighborhood Hits	600	Target Neighborhood Hits	1006	Shared Neighborhood Hits	55
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

ADA25_MOUSE
NC score	0.051871 (rank : 1044)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	600	Target Neighborhood Hits	213	Shared Neighborhood Hits	116
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

YES_MOUSE
NC score	0.051859 (rank : 1045)	θ value	θ > 10 (rank : 1202)
Query Neighborhood Hits	600	Target Neighborhood Hits	1052	Shared Neighborhood Hits	59
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

OX2G_MOUSE
NC score	0.051846 (rank : 1046)	θ value	θ > 10 (rank : 999)
Query Neighborhood Hits	600	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	O54901, O54816, Q9JHD5	Gene names	Cd200, Mox2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen).

BLK_HUMAN
NC score	0.051835 (rank : 1047)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	600	Target Neighborhood Hits	994	Shared Neighborhood Hits	54
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

MFAP4_MOUSE
NC score	0.051780 (rank : 1048)	θ value	θ > 10 (rank : 951)
Query Neighborhood Hits	600	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

LYN_MOUSE
NC score	0.051745 (rank : 1049)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	600	Target Neighborhood Hits	1023	Shared Neighborhood Hits	55
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

FGR_HUMAN
NC score	0.051743 (rank : 1050)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	600	Target Neighborhood Hits	1067	Shared Neighborhood Hits	58
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

MFAP4_HUMAN
NC score	0.051703 (rank : 1051)	θ value	θ > 10 (rank : 950)
Query Neighborhood Hits	600	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

LYN_HUMAN
NC score	0.051632 (rank : 1052)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	600	Target Neighborhood Hits	1022	Shared Neighborhood Hits	54
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

SRC_MOUSE
NC score	0.051629 (rank : 1053)	θ value	θ > 10 (rank : 1124)
Query Neighborhood Hits	600	Target Neighborhood Hits	1033	Shared Neighborhood Hits	57
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

FGR_MOUSE
NC score	0.051583 (rank : 1054)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	600	Target Neighborhood Hits	1069	Shared Neighborhood Hits	58
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FRK_HUMAN
NC score	0.051540 (rank : 1055)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	600	Target Neighborhood Hits	1058	Shared Neighborhood Hits	55
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

ABL1_HUMAN
NC score	0.051371 (rank : 1056)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	600	Target Neighborhood Hits	1220	Shared Neighborhood Hits	62
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

PHXR5_MOUSE
NC score	0.051263 (rank : 1057)	θ value	θ > 10 (rank : 1021)
Query Neighborhood Hits	600	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

ABL2_HUMAN
NC score	0.051260 (rank : 1058)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	600	Target Neighborhood Hits	1045	Shared Neighborhood Hits	59
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

BTC_HUMAN
NC score	0.051184 (rank : 1059)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	600	Target Neighborhood Hits	70	Shared Neighborhood Hits	37
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

SRC_HUMAN
NC score	0.051162 (rank : 1060)	θ value	θ > 10 (rank : 1123)
Query Neighborhood Hits	600	Target Neighborhood Hits	1058	Shared Neighborhood Hits	58
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

PVRL2_MOUSE
NC score	0.050882 (rank : 1061)	θ value	θ > 10 (rank : 1085)
Query Neighborhood Hits	600	Target Neighborhood Hits	242	Shared Neighborhood Hits	39
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

CSK_HUMAN
NC score	0.050879 (rank : 1062)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	600	Target Neighborhood Hits	1009	Shared Neighborhood Hits	58
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

BTC_MOUSE
NC score	0.050511 (rank : 1063)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	600	Target Neighborhood Hits	67	Shared Neighborhood Hits	38
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

ADM1A_MOUSE
NC score	0.050410 (rank : 1064)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	600	Target Neighborhood Hits	230	Shared Neighborhood Hits	120
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

FYN_MOUSE
NC score	0.050338 (rank : 1065)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	600	Target Neighborhood Hits	1073	Shared Neighborhood Hits	57
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

PTK6_MOUSE
NC score	0.050287 (rank : 1066)	θ value	θ > 10 (rank : 1041)
Query Neighborhood Hits	600	Target Neighborhood Hits	1026	Shared Neighborhood Hits	54
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

TEX14_HUMAN
NC score	0.050157 (rank : 1067)	θ value	θ > 10 (rank : 1141)
Query Neighborhood Hits	600	Target Neighborhood Hits	1103	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TPA_HUMAN
NC score	0.050106 (rank : 1068)	θ value	θ > 10 (rank : 1160)
Query Neighborhood Hits	600	Target Neighborhood Hits	324	Shared Neighborhood Hits	110
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

GP112_HUMAN
NC score	0.048850 (rank : 1069)	θ value	0.62314 (rank : 403)
Query Neighborhood Hits	600	Target Neighborhood Hits	441	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

TRIM9_HUMAN
NC score	0.047516 (rank : 1070)	θ value	6.88961 (rank : 566)
Query Neighborhood Hits	600	Target Neighborhood Hits	294	Shared Neighborhood Hits	54
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

FANK1_HUMAN
NC score	0.046647 (rank : 1071)	θ value	4.03905 (rank : 496)
Query Neighborhood Hits	600	Target Neighborhood Hits	326	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

SPY1_HUMAN
NC score	0.046521 (rank : 1072)	θ value	0.163984 (rank : 370)
Query Neighborhood Hits	600	Target Neighborhood Hits	64	Shared Neighborhood Hits	44
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

FANK1_MOUSE
NC score	0.045249 (rank : 1073)	θ value	6.88961 (rank : 547)
Query Neighborhood Hits	600	Target Neighborhood Hits	325	Shared Neighborhood Hits	52
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

TRIM9_MOUSE
NC score	0.044511 (rank : 1074)	θ value	1.81305 (rank : 460)
Query Neighborhood Hits	600	Target Neighborhood Hits	274	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TR10D_HUMAN
NC score	0.043404 (rank : 1075)	θ value	1.38821 (rank : 438)
Query Neighborhood Hits	600	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

THYG_MOUSE
NC score	0.042919 (rank : 1076)	θ value	3.0926 (rank : 486)
Query Neighborhood Hits	600	Target Neighborhood Hits	161	Shared Neighborhood Hits	80
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

ADM1B_MOUSE
NC score	0.042060 (rank : 1077)	θ value	8.99809 (rank : 574)
Query Neighborhood Hits	600	Target Neighborhood Hits	236	Shared Neighborhood Hits	109
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA30_HUMAN
NC score	0.041401 (rank : 1078)	θ value	8.99809 (rank : 573)
Query Neighborhood Hits	600	Target Neighborhood Hits	391	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

CSTN3_HUMAN
NC score	0.040311 (rank : 1079)	θ value	0.0431538 (rank : 340)
Query Neighborhood Hits	600	Target Neighborhood Hits	145	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BQT9, O94831	Gene names	CLSTN3, CS3, KIAA0726
Domain Architecture
Description	Calsyntenin-3 precursor.

PAP2_HUMAN
NC score	0.039285 (rank : 1080)	θ value	1.38821 (rank : 434)
Query Neighborhood Hits	600	Target Neighborhood Hits	106	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

CSTN3_MOUSE
NC score	0.038698 (rank : 1081)	θ value	0.279714 (rank : 379)
Query Neighborhood Hits	600	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q99JH7	Gene names	Clstn3, Cs3, Cstn3
Domain Architecture
Description	Calsyntenin-3 precursor.

CAD23_MOUSE
NC score	0.038502 (rank : 1082)	θ value	4.03905 (rank : 495)
Query Neighborhood Hits	600	Target Neighborhood Hits	208	Shared Neighborhood Hits	25
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

ADA21_HUMAN
NC score	0.038130 (rank : 1083)	θ value	8.99809 (rank : 572)
Query Neighborhood Hits	600	Target Neighborhood Hits	181	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

CT195_MOUSE
NC score	0.035817 (rank : 1084)	θ value	3.0926 (rank : 475)
Query Neighborhood Hits	600	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q80WB0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf195 homolog.

TYRO_HUMAN
NC score	0.034559 (rank : 1085)	θ value	5.27518 (rank : 536)
Query Neighborhood Hits	600	Target Neighborhood Hits	35	Shared Neighborhood Hits	21
SwissProt Accessions	P14679, Q15675, Q15676, Q15680, Q8TAK4, Q9BYY0, Q9BZX1	Gene names	TYR
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Tumor rejection antigen AB) (SK29-AB) (LB24-AB).

MYT1_MOUSE
NC score	0.034147 (rank : 1086)	θ value	0.0113563 (rank : 311)
Query Neighborhood Hits	600	Target Neighborhood Hits	385	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

ZN363_HUMAN
NC score	0.034147 (rank : 1087)	θ value	4.03905 (rank : 512)
Query Neighborhood Hits	600	Target Neighborhood Hits	162	Shared Neighborhood Hits	27
SwissProt Accessions	Q96PM5, Q96PR5	Gene names	RCHY1, ARNIP, CHIMP, PIRH2, ZNF363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein) (p53 induced RING-H2 protein) (hPirh2).

GP110_HUMAN
NC score	0.032546 (rank : 1088)	θ value	5.27518 (rank : 516)
Query Neighborhood Hits	600	Target Neighborhood Hits	87	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

ANR38_MOUSE
NC score	0.032318 (rank : 1089)	θ value	1.81305 (rank : 440)
Query Neighborhood Hits	600	Target Neighborhood Hits	512	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

SAMH1_HUMAN
NC score	0.032121 (rank : 1090)	θ value	0.0961366 (rank : 358)
Query Neighborhood Hits	600	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3Z3, Q5JXG8, Q9H004, Q9H005, Q9H3U9	Gene names	SAMHD1, MOP5
Domain Architecture
Description	SAM domain and HD domain-containing protein 1 (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5).

RIMB1_HUMAN
NC score	0.031747 (rank : 1091)	θ value	8.99809 (rank : 592)
Query Neighborhood Hits	600	Target Neighborhood Hits	1479	Shared Neighborhood Hits	56
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SAMH1_MOUSE
NC score	0.031735 (rank : 1092)	θ value	0.0961366 (rank : 359)
Query Neighborhood Hits	600	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q60710, Q91VK8	Gene names	Samhd1, Mg11
Domain Architecture
Description	SAM domain and HD domain-containing protein 1 (Interferon-gamma- inducible protein Mg11).

CT111_HUMAN
NC score	0.030866 (rank : 1093)	θ value	0.62314 (rank : 402)
Query Neighborhood Hits	600	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NX31, O95912, Q9NZ84, Q9P0R8	Gene names	C20orf111
Domain Architecture
Description	Uncharacterized protein C20orf111.

NACAM_MOUSE
NC score	0.030431 (rank : 1094)	θ value	4.03905 (rank : 504)
Query Neighborhood Hits	600	Target Neighborhood Hits	1866	Shared Neighborhood Hits	87
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

COFA1_MOUSE
NC score	0.030195 (rank : 1095)	θ value	0.0961366 (rank : 354)
Query Neighborhood Hits	600	Target Neighborhood Hits	305	Shared Neighborhood Hits	30
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

FHL2_MOUSE
NC score	0.029947 (rank : 1096)	θ value	0.0563607 (rank : 344)
Query Neighborhood Hits	600	Target Neighborhood Hits	539	Shared Neighborhood Hits	60
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

MYT1_HUMAN
NC score	0.029793 (rank : 1097)	θ value	0.0330416 (rank : 336)
Query Neighborhood Hits	600	Target Neighborhood Hits	475	Shared Neighborhood Hits	18
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

MYT1L_MOUSE
NC score	0.029046 (rank : 1098)	θ value	0.0961366 (rank : 356)
Query Neighborhood Hits	600	Target Neighborhood Hits	461	Shared Neighborhood Hits	19
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

MYT1L_HUMAN
NC score	0.027751 (rank : 1099)	θ value	0.125558 (rank : 365)
Query Neighborhood Hits	600	Target Neighborhood Hits	471	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

TYRO_MOUSE
NC score	0.027287 (rank : 1100)	θ value	5.27518 (rank : 537)
Query Neighborhood Hits	600	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P11344	Gene names	Tyr
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Albino locus protein).

SORC1_MOUSE
NC score	0.026335 (rank : 1101)	θ value	0.47712 (rank : 399)
Query Neighborhood Hits	600	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JLC4, Q8VI45, Q922I1, Q9QY21	Gene names	Sorcs1, Sorcs
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (mSorCS).

SORC1_HUMAN
NC score	0.026195 (rank : 1102)	θ value	0.47712 (rank : 398)
Query Neighborhood Hits	600	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WY21, Q59GG7, Q5JVT7, Q5JVT8, Q5VY14, Q86WQ1, Q86WQ2, Q9H1Y1, Q9H1Y2	Gene names	SORCS1, SORCS
Domain Architecture
Description	VPS10 domain-containing receptor SorCS1 precursor (hSorCS).

PTX3_HUMAN
NC score	0.025641 (rank : 1103)	θ value	0.813845 (rank : 417)
Query Neighborhood Hits	600	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	P26022	Gene names	PTX3, TSG14
Domain Architecture
Description	Pentraxin-related protein PTX3 precursor (Pentaxin-related protein PTX3) (Tumor necrosis factor-inducible protein TSG-14).

SPY2_HUMAN
NC score	0.025467 (rank : 1104)	θ value	8.99809 (rank : 593)
Query Neighborhood Hits	600	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

PCDH8_HUMAN
NC score	0.024199 (rank : 1105)	θ value	8.99809 (rank : 589)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	O95206, Q8IYE9, Q96SF1	Gene names	PCDH8
Domain Architecture
Description	Protocadherin-8 precursor (Arcadlin).

ULK2_HUMAN
NC score	0.023426 (rank : 1106)	θ value	5.27518 (rank : 538)
Query Neighborhood Hits	600	Target Neighborhood Hits	979	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

BPAEA_HUMAN
NC score	0.023265 (rank : 1107)	θ value	0.813845 (rank : 412)
Query Neighborhood Hits	600	Target Neighborhood Hits	1369	Shared Neighborhood Hits	32
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

SSRG_HUMAN
NC score	0.023256 (rank : 1108)	θ value	1.06291 (rank : 428)
Query Neighborhood Hits	600	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNL2	Gene names	SSR3, TRAPG
Domain Architecture
Description	Translocon-associated protein subunit gamma (TRAP-gamma) (Signal sequence receptor subunit gamma) (SSR-gamma).

PCDBF_HUMAN
NC score	0.023022 (rank : 1109)	θ value	1.06291 (rank : 426)
Query Neighborhood Hits	600	Target Neighborhood Hits	164	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5E8, Q8IUX5	Gene names	PCDHB15
Domain Architecture
Description	Protocadherin beta 15 precursor (PCDH-beta15).

PME17_HUMAN
NC score	0.022754 (rank : 1110)	θ value	0.62314 (rank : 406)
Query Neighborhood Hits	600	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	P40967, Q12763, Q14448, Q14817, Q16565	Gene names	SILV, D12S53E, PMEL17
Domain Architecture
Description	Melanocyte protein Pmel 17 precursor (Melanocyte lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (ME20M/ME20S) (ME20- M/ME20-S) (95 kDa melanocyte-specific secreted glycoprotein).

FHL2_HUMAN
NC score	0.022522 (rank : 1111)	θ value	0.279714 (rank : 380)
Query Neighborhood Hits	600	Target Neighborhood Hits	533	Shared Neighborhood Hits	58
SwissProt Accessions	Q14192, Q13229, Q13644, Q9P294	Gene names	FHL2, DRAL, SLIM3
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3) (LIM-domain protein DRAL).

CO5A1_HUMAN
NC score	0.022498 (rank : 1112)	θ value	1.38821 (rank : 431)
Query Neighborhood Hits	600	Target Neighborhood Hits	434	Shared Neighborhood Hits	33
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

SSRG_MOUSE
NC score	0.022226 (rank : 1113)	θ value	1.38821 (rank : 437)
Query Neighborhood Hits	600	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DCF9, Q8C0Z8	Gene names	Ssr3
Domain Architecture	No domain graphic available
Description	Translocon-associated protein subunit gamma (TRAP-gamma) (Signal sequence receptor subunit gamma) (SSR-gamma).

MLL2_HUMAN
NC score	0.021776 (rank : 1114)	θ value	6.88961 (rank : 553)
Query Neighborhood Hits	600	Target Neighborhood Hits	1788	Shared Neighborhood Hits	88
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ST18_MOUSE
NC score	0.020391 (rank : 1115)	θ value	6.88961 (rank : 560)
Query Neighborhood Hits	600	Target Neighborhood Hits	248	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TY4, Q3UH00, Q3URH9, Q3UVB9, Q3UZN9, Q811B4, Q8K098	Gene names	St18, Kiaa0535
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18.

ANK3_HUMAN
NC score	0.020204 (rank : 1116)	θ value	8.99809 (rank : 575)
Query Neighborhood Hits	600	Target Neighborhood Hits	853	Shared Neighborhood Hits	39
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

FLRT1_HUMAN
NC score	0.019885 (rank : 1117)	θ value	0.21417 (rank : 374)
Query Neighborhood Hits	600	Target Neighborhood Hits	286	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZU1	Gene names	FLRT1
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT1 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 1).

WNK1_MOUSE
NC score	0.019575 (rank : 1118)	θ value	6.88961 (rank : 568)
Query Neighborhood Hits	600	Target Neighborhood Hits	1179	Shared Neighborhood Hits	69
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

TRI18_HUMAN
NC score	0.019364 (rank : 1119)	θ value	4.03905 (rank : 509)
Query Neighborhood Hits	600	Target Neighborhood Hits	307	Shared Neighborhood Hits	41
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

CI079_HUMAN
NC score	0.019040 (rank : 1120)	θ value	1.38821 (rank : 430)
Query Neighborhood Hits	600	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

TICN1_MOUSE
NC score	0.018253 (rank : 1121)	θ value	5.27518 (rank : 532)
Query Neighborhood Hits	600	Target Neighborhood Hits	79	Shared Neighborhood Hits	14
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TACD1_HUMAN
NC score	0.017588 (rank : 1122)	θ value	2.36792 (rank : 467)
Query Neighborhood Hits	600	Target Neighborhood Hits	34	Shared Neighborhood Hits	10
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

TICN1_HUMAN
NC score	0.017577 (rank : 1123)	θ value	8.99809 (rank : 595)
Query Neighborhood Hits	600	Target Neighborhood Hits	70	Shared Neighborhood Hits	15
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

LYPD3_MOUSE
NC score	0.016376 (rank : 1124)	θ value	0.62314 (rank : 405)
Query Neighborhood Hits	600	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YK8	Gene names	Lypd3, C4.4a
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 3 precursor (GPI-anchored metastasis-associated protein C4.4A homolog).

MAML3_HUMAN
NC score	0.014779 (rank : 1125)	θ value	0.813845 (rank : 416)
Query Neighborhood Hits	600	Target Neighborhood Hits	323	Shared Neighborhood Hits	20
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

TRI18_MOUSE
NC score	0.014694 (rank : 1126)	θ value	1.06291 (rank : 429)
Query Neighborhood Hits	600	Target Neighborhood Hits	292	Shared Neighborhood Hits	27
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TNC6B_HUMAN
NC score	0.013652 (rank : 1127)	θ value	5.27518 (rank : 534)
Query Neighborhood Hits	600	Target Neighborhood Hits	256	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

ZN363_MOUSE
NC score	0.012896 (rank : 1128)	θ value	5.27518 (rank : 541)
Query Neighborhood Hits	600	Target Neighborhood Hits	134	Shared Neighborhood Hits	16
SwissProt Accessions	Q9CR50, Q920H0	Gene names	Rchy1, Arnip, Chimp, Zfp363, Znf363
Domain Architecture
Description	RING finger and CHY zinc finger domain-containing protein 1 (Zinc finger protein 363) (CH-rich-interacting match with PLAG1) (Androgen receptor N-terminal-interacting protein).

DGKE_HUMAN
NC score	0.012556 (rank : 1129)	θ value	0.21417 (rank : 372)
Query Neighborhood Hits	600	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	P52429, Q9UKQ3	Gene names	DGKE, DAGK5
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

CR2_MOUSE
NC score	0.010941 (rank : 1130)	θ value	6.88961 (rank : 546)
Query Neighborhood Hits	600	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

EP300_HUMAN
NC score	0.010837 (rank : 1131)	θ value	5.27518 (rank : 514)
Query Neighborhood Hits	600	Target Neighborhood Hits	821	Shared Neighborhood Hits	41
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

SMS2_HUMAN
NC score	0.010609 (rank : 1132)	θ value	1.38821 (rank : 436)
Query Neighborhood Hits	600	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHU3	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

MAST1_MOUSE
NC score	0.009722 (rank : 1133)	θ value	1.06291 (rank : 424)
Query Neighborhood Hits	600	Target Neighborhood Hits	1123	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

PELI3_HUMAN
NC score	0.009314 (rank : 1134)	θ value	1.81305 (rank : 455)
Query Neighborhood Hits	600	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N2H9, Q8N3E1, Q8N9Q6, Q8TAW7, Q8TED5	Gene names	PELI3
Domain Architecture
Description	Protein pellino homolog 3 (Pellino-3).

RNC_HUMAN
NC score	0.009300 (rank : 1135)	θ value	5.27518 (rank : 530)
Query Neighborhood Hits	600	Target Neighborhood Hits	176	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRR4, Q7Z5V2, Q86YH0, Q9NW73, Q9Y2V9, Q9Y4Y0	Gene names	RNASEN, RN3, RNASE3L
Domain Architecture
Description	Ribonuclease III (EC 3.1.26.3) (RNase III) (Drosha) (p241).

PELI3_MOUSE
NC score	0.009289 (rank : 1136)	θ value	1.81305 (rank : 456)
Query Neighborhood Hits	600	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BXR6, Q8K329	Gene names	Peli3
Domain Architecture
Description	Protein pellino homolog 3 (Pellino-3).

ZDHC1_HUMAN
NC score	0.009265 (rank : 1137)	θ value	1.81305 (rank : 462)
Query Neighborhood Hits	600	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

OXSM_HUMAN
NC score	0.008743 (rank : 1138)	θ value	3.0926 (rank : 482)
Query Neighborhood Hits	600	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NWU1	Gene names	OXSM
Domain Architecture	No domain graphic available
Description	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial precursor (EC 2.3.1.41) (Beta-ketoacyl synthase).

FRMD6_HUMAN
NC score	0.008742 (rank : 1139)	θ value	1.81305 (rank : 444)
Query Neighborhood Hits	600	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

SMS2_MOUSE
NC score	0.008410 (rank : 1140)	θ value	4.03905 (rank : 505)
Query Neighborhood Hits	600	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D4B1	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

TMEM5_HUMAN
NC score	0.007265 (rank : 1141)	θ value	5.27518 (rank : 533)
Query Neighborhood Hits	600	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2B1, Q6PKD6	Gene names	TMEM5
Domain Architecture	No domain graphic available
Description	Transmembrane protein 5.

ZDHC8_HUMAN
NC score	0.007223 (rank : 1142)	θ value	3.0926 (rank : 489)
Query Neighborhood Hits	600	Target Neighborhood Hits	234	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULC8, Q6ICL1, Q6ZNF5, Q7Z6L9	Gene names	ZDHHC8, KIAA1292, ZDHHCL1, ZNF378
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378).

FBXL6_MOUSE
NC score	0.006794 (rank : 1143)	θ value	3.0926 (rank : 476)
Query Neighborhood Hits	600	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXW0, Q9JJD7	Gene names	Fbxl6, Fbl6
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 6 (F-box and leucine-rich repeat protein 6) (F-box protein FBL6).

FRMD6_MOUSE
NC score	0.006484 (rank : 1144)	θ value	6.88961 (rank : 549)
Query Neighborhood Hits	600	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

TLN2_HUMAN
NC score	0.006223 (rank : 1145)	θ value	4.03905 (rank : 506)
Query Neighborhood Hits	600	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
NC score	0.006166 (rank : 1146)	θ value	6.88961 (rank : 564)
Query Neighborhood Hits	600	Target Neighborhood Hits	149	Shared Neighborhood Hits	11
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

KRHB1_HUMAN
NC score	0.005939 (rank : 1147)	θ value	0.813845 (rank : 415)
Query Neighborhood Hits	600	Target Neighborhood Hits	461	Shared Neighborhood Hits	33
SwissProt Accessions	Q14533, Q14846, Q16274, Q8WU52, Q9BR74	Gene names	KRTHB1, MLN137
Domain Architecture
Description	Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) (ghHb1) (MLN 137).

SYPM_MOUSE
NC score	0.005658 (rank : 1148)	θ value	6.88961 (rank : 561)
Query Neighborhood Hits	600	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CFI5, Q8R0C4	Gene names	Pars2
Domain Architecture	No domain graphic available
Description	Probable prolyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.15) (Proline--tRNA ligase) (ProRS).

4ET_MOUSE
NC score	0.005657 (rank : 1149)	θ value	8.99809 (rank : 570)
Query Neighborhood Hits	600	Target Neighborhood Hits	103	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

CASZ1_HUMAN
NC score	0.005589 (rank : 1150)	θ value	8.99809 (rank : 577)
Query Neighborhood Hits	600	Target Neighborhood Hits	473	Shared Neighborhood Hits	25
SwissProt Accessions	Q86V15, Q5T9S1, Q8WX49, Q8WX50, Q9BT16, Q9NXC6	Gene names	CASZ1, CST, ZNF693
Domain Architecture	No domain graphic available
Description	Castor homolog 1 zinc finger protein (Castor-related protein) (Zinc finger protein 693).

IGHA1_HUMAN
NC score	0.005176 (rank : 1151)	θ value	2.36792 (rank : 466)
Query Neighborhood Hits	600	Target Neighborhood Hits	194	Shared Neighborhood Hits	10
SwissProt Accessions	P01876	Gene names	IGHA1
Domain Architecture
Description	Ig alpha-1 chain C region.

ZDHC8_MOUSE
NC score	0.005103 (rank : 1152)	θ value	4.03905 (rank : 511)
Query Neighborhood Hits	600	Target Neighborhood Hits	243	Shared Neighborhood Hits	17
SwissProt Accessions	Q5Y5T5, Q7TNF7	Gene names	Zdhhc8
Domain Architecture	No domain graphic available
Description	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 8) (DHHC-8).

ATS2_MOUSE
NC score	0.004811 (rank : 1153)	θ value	8.99809 (rank : 576)
Query Neighborhood Hits	600	Target Neighborhood Hits	179	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C9W3	Gene names	Adamts2
Domain Architecture
Description	ADAMTS-2 precursor (EC 3.4.24.14) (A disintegrin and metalloproteinase with thrombospondin motifs 2) (ADAM-TS 2) (ADAM-TS2) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen I N-proteinase) (PC I-NP) (Procollagen N-endopeptidase) (pNPI).

KRHB3_HUMAN
NC score	0.004672 (rank : 1154)	θ value	6.88961 (rank : 551)
Query Neighborhood Hits	600	Target Neighborhood Hits	438	Shared Neighborhood Hits	29
SwissProt Accessions	P78385, Q9NSB3	Gene names	KRTHB3
Domain Architecture
Description	Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3).

RAG2_HUMAN
NC score	0.004256 (rank : 1155)	θ value	8.99809 (rank : 591)
Query Neighborhood Hits	600	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P55895, Q8TBL4	Gene names	RAG2
Domain Architecture
Description	V(D)J recombination-activating protein 2 (RAG-2).

DEN1A_MOUSE
NC score	0.004165 (rank : 1156)	θ value	8.99809 (rank : 581)
Query Neighborhood Hits	600	Target Neighborhood Hits	178	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

ABLM2_HUMAN
NC score	0.003995 (rank : 1157)	θ value	3.0926 (rank : 472)
Query Neighborhood Hits	600	Target Neighborhood Hits	317	Shared Neighborhood Hits	26
SwissProt Accessions	Q6H8Q1, Q6H8Q0, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7	Gene names	ABLIM2, KIAA1808
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

TFE2_MOUSE
NC score	0.003903 (rank : 1158)	θ value	5.27518 (rank : 531)
Query Neighborhood Hits	600	Target Neighborhood Hits	118	Shared Neighborhood Hits	5
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

ZN221_HUMAN
NC score	0.003821 (rank : 1159)	θ value	5.27518 (rank : 540)
Query Neighborhood Hits	600	Target Neighborhood Hits	784	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UK13, Q9P1U8	Gene names	ZNF221
Domain Architecture
Description	Zinc finger protein 221.

ASM3B_HUMAN
NC score	0.003533 (rank : 1160)	θ value	6.88961 (rank : 543)
Query Neighborhood Hits	600	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q92485, Q5T0Z0, Q96CB7	Gene names	SMPDL3B, ASML3B
Domain Architecture
Description	Acid sphingomyelinase-like phosphodiesterase 3b precursor (EC 3.1.4.-) (ASM-like phosphodiesterase 3b).

FUT7_HUMAN
NC score	0.003343 (rank : 1161)	θ value	5.27518 (rank : 515)
Query Neighborhood Hits	600	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q11130, Q6DK54	Gene names	FUT7
Domain Architecture
Description	Alpha-(1,3)-fucosyltransferase (EC 2.4.1.-) (Galactoside 3-L- fucosyltransferase) (Fucosyltransferase 7) (FUCT-VII) (Selectin-ligand synthase).

PHF3_HUMAN
NC score	0.002882 (rank : 1162)	θ value	5.27518 (rank : 528)
Query Neighborhood Hits	600	Target Neighborhood Hits	419	Shared Neighborhood Hits	16
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

MOT4_MOUSE
NC score	0.002736 (rank : 1163)	θ value	4.03905 (rank : 501)
Query Neighborhood Hits	600	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P57787, Q9ES80, Q9ESF8	Gene names	Slc16a3, Mct4
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3).

FBLI1_MOUSE
NC score	0.002603 (rank : 1164)	θ value	8.99809 (rank : 582)
Query Neighborhood Hits	600	Target Neighborhood Hits	228	Shared Neighborhood Hits	14
SwissProt Accessions	Q71FD7, Q99J35	Gene names	Fblim1, Cal
Domain Architecture	No domain graphic available
Description	Filamin-binding LIM protein 1 (CSX-associated LIM).

RNAS2_MOUSE
NC score	0.002531 (rank : 1165)	θ value	6.88961 (rank : 558)
Query Neighborhood Hits	600	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	O35291	Gene names	Rnase2, Ear4
Domain Architecture
Description	Nonsecretory ribonuclease precursor (EC 3.1.27.5) (Eosinophil cationic-type ribonuclease 4) (MR-4) (Ribonuclease 2).

UBP36_HUMAN
NC score	0.002331 (rank : 1166)	θ value	6.88961 (rank : 567)
Query Neighborhood Hits	600	Target Neighborhood Hits	232	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

ZN155_HUMAN
NC score	0.001817 (rank : 1167)	θ value	0.279714 (rank : 384)
Query Neighborhood Hits	600	Target Neighborhood Hits	786	Shared Neighborhood Hits	54
SwissProt Accessions	Q12901, Q9UIE1, Q9UK14	Gene names	ZNF155
Domain Architecture
Description	Zinc finger protein 155.

MGR1_HUMAN
NC score	0.001791 (rank : 1168)	θ value	4.03905 (rank : 500)
Query Neighborhood Hits	600	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

KLRA8_MOUSE
NC score	0.001790 (rank : 1169)	θ value	6.88961 (rank : 550)
Query Neighborhood Hits	600	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q60682, O78027	Gene names	Klra8, Ly-49h, Ly49-h, Ly49H
Domain Architecture
Description	Killer cell lectin-like receptor 8 (T-cell surface glycoprotein Ly- 49H) (Ly49-H antigen) (Lymphocyte antigen 49H).

VMDL3_MOUSE
NC score	0.001569 (rank : 1170)	θ value	8.99809 (rank : 597)
Query Neighborhood Hits	600	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q6H1V1	Gene names	Vmd2l3
Domain Architecture	No domain graphic available
Description	Bestrophin-4 (Vitelliform macular dystrophy 2-like protein 3).

CATE_MOUSE
NC score	0.001438 (rank : 1171)	θ value	6.88961 (rank : 545)
Query Neighborhood Hits	600	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	P70269, O35647	Gene names	Ctse
Domain Architecture
Description	Cathepsin E precursor (EC 3.4.23.34).

ALDR_HUMAN
NC score	0.000844 (rank : 1172)	θ value	5.27518 (rank : 513)
Query Neighborhood Hits	600	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P15121, Q9BS21, Q9UCI9	Gene names	AKR1B1, ALDR1
Domain Architecture
Description	Aldose reductase (EC 1.1.1.21) (AR) (Aldehyde reductase).

SRGEF_HUMAN
NC score	0.000817 (rank : 1173)	θ value	8.99809 (rank : 594)
Query Neighborhood Hits	600	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGK8, Q9UGK9	Gene names	SERGEF, DELGEF, GNEFR
Domain Architecture	No domain graphic available
Description	Secretion-regulating guanine nucleotide exchange factor (Guanine nucleotide exchange factor-related protein) (Deafness locus-associated putative guanine nucleotide exchange factor) (DelGEF).

POK7_HUMAN
NC score	0.000468 (rank : 1174)	θ value	6.88961 (rank : 555)
Query Neighborhood Hits	600	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QC07, Q6QAI9, Q96PI5	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K18 Pol protein) (HERV-K110 Pol protein) (HERV-K(C1a) Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H)].

MGR4_HUMAN
NC score	0.000417 (rank : 1175)	θ value	5.27518 (rank : 523)
Query Neighborhood Hits	600	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

ZN678_HUMAN
NC score	-0.000561 (rank : 1176)	θ value	0.62314 (rank : 410)
Query Neighborhood Hits	600	Target Neighborhood Hits	761	Shared Neighborhood Hits	44
SwissProt Accessions	Q5SXM1, Q8IVQ9	Gene names	ZNF678
Domain Architecture	No domain graphic available
Description	Zinc finger protein 678.

TBX18_MOUSE
NC score	-0.000672 (rank : 1177)	θ value	6.88961 (rank : 562)
Query Neighborhood Hits	600	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

DBNL_MOUSE
NC score	-0.001101 (rank : 1178)	θ value	8.99809 (rank : 580)
Query Neighborhood Hits	600	Target Neighborhood Hits	306	Shared Neighborhood Hits	3
SwissProt Accessions	Q62418, Q80WP1, Q8BH56	Gene names	Dbnl, Abp1, Sh3p7
Domain Architecture	No domain graphic available
Description	Drebrin-like protein (SH3 domain-containing protein 7) (Actin-binding protein 1).

WNT16_MOUSE
NC score	-0.001530 (rank : 1179)	θ value	6.88961 (rank : 569)
Query Neighborhood Hits	600	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QYS1	Gene names	Wnt16
Domain Architecture
Description	Protein Wnt-16 precursor.

ZN226_HUMAN
NC score	-0.001681 (rank : 1180)	θ value	3.0926 (rank : 492)
Query Neighborhood Hits	600	Target Neighborhood Hits	770	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NYT6, Q96TE6, Q9NS44	Gene names	ZNF226
Domain Architecture
Description	Zinc finger protein 226.

ZN184_HUMAN
NC score	-0.002269 (rank : 1181)	θ value	0.125558 (rank : 367)
Query Neighborhood Hits	600	Target Neighborhood Hits	811	Shared Neighborhood Hits	45
SwissProt Accessions	Q99676, O60792, Q8TBA9	Gene names	ZNF184
Domain Architecture
Description	Zinc finger protein 184.

BRWD1_MOUSE
NC score	-0.002742 (rank : 1182)	θ value	1.81305 (rank : 441)
Query Neighborhood Hits	600	Target Neighborhood Hits	478	Shared Neighborhood Hits	11
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

MAP1A_HUMAN
NC score	-0.002771 (rank : 1183)	θ value	5.27518 (rank : 521)
Query Neighborhood Hits	600	Target Neighborhood Hits	1626	Shared Neighborhood Hits	35
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TCF17_HUMAN
NC score	-0.003051 (rank : 1184)	θ value	6.88961 (rank : 563)
Query Neighborhood Hits	600	Target Neighborhood Hits	797	Shared Neighborhood Hits	46
SwissProt Accessions	O60765, Q9UNJ8	Gene names	ZNF354A, EZNF, HKL1, TCF17
Domain Architecture
Description	Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF).

ZN228_HUMAN
NC score	-0.003055 (rank : 1185)	θ value	8.99809 (rank : 598)
Query Neighborhood Hits	600	Target Neighborhood Hits	775	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UJU3, Q9HCA7	Gene names	ZNF228
Domain Architecture
Description	Zinc finger protein 228.

MCPT2_MOUSE
NC score	-0.003259 (rank : 1186)	θ value	5.27518 (rank : 522)
Query Neighborhood Hits	600	Target Neighborhood Hits	175	Shared Neighborhood Hits	7
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

ZN611_HUMAN
NC score	-0.003262 (rank : 1187)	θ value	0.0193708 (rank : 325)
Query Neighborhood Hits	600	Target Neighborhood Hits	769	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N823, Q69YG9	Gene names	ZNF611
Domain Architecture	No domain graphic available
Description	Zinc finger protein 611.

ZNF23_HUMAN
NC score	-0.003568 (rank : 1188)	θ value	0.00869519 (rank : 306)
Query Neighborhood Hits	600	Target Neighborhood Hits	750	Shared Neighborhood Hits	37
SwissProt Accessions	P17027, Q96IT3, Q9UG42	Gene names	ZNF23, KOX16, ZNF359
Domain Architecture
Description	Zinc finger protein 23 (Zinc finger protein 359) (Zinc finger protein KOX16).

ZN195_HUMAN
NC score	-0.003692 (rank : 1189)	θ value	3.0926 (rank : 491)
Query Neighborhood Hits	600	Target Neighborhood Hits	760	Shared Neighborhood Hits	37
SwissProt Accessions	O14628	Gene names	ZNF195, ZNFP104
Domain Architecture
Description	Zinc finger protein 195.

FOG2_MOUSE
NC score	-0.003757 (rank : 1190)	θ value	8.99809 (rank : 585)
Query Neighborhood Hits	600	Target Neighborhood Hits	714	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CCH7, Q9Z0F2	Gene names	Zfpm2, Fog2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (Friend of GATA-2) (FOG-2) (mFOG-2).

FOG2_HUMAN
NC score	-0.003793 (rank : 1191)	θ value	8.99809 (rank : 584)
Query Neighborhood Hits	600	Target Neighborhood Hits	731	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WW38, Q9NPL7, Q9NPS4, Q9UNI5	Gene names	ZFPM2, FOG2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (FOG-2) (hFOG-2).

BRWD1_HUMAN
NC score	-0.003910 (rank : 1192)	θ value	6.88961 (rank : 544)
Query Neighborhood Hits	600	Target Neighborhood Hits	448	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

ZN700_HUMAN
NC score	-0.004087 (rank : 1193)	θ value	8.99809 (rank : 599)
Query Neighborhood Hits	600	Target Neighborhood Hits	772	Shared Neighborhood Hits	40
SwissProt Accessions	Q9H0M5	Gene names	ZNF700
Domain Architecture	No domain graphic available
Description	Zinc finger protein 700.

ZN33A_HUMAN
NC score	-0.004212 (rank : 1194)	θ value	0.365318 (rank : 395)
Query Neighborhood Hits	600	Target Neighborhood Hits	780	Shared Neighborhood Hits	33
SwissProt Accessions	Q06730, Q5VZ86	Gene names	ZNF33A, KIAA0065, KOX31, ZNF33
Domain Architecture
Description	Zinc finger protein 33A (Zinc finger protein KOX31) (Zinc finger and ZAK-associated protein with KRAB domain) (ZZaPK).

HB2B_HUMAN
NC score	-0.004318 (rank : 1195)	θ value	5.27518 (rank : 518)
Query Neighborhood Hits	600	Target Neighborhood Hits	209	Shared Neighborhood Hits	5
SwissProt Accessions	P01912	Gene names
Domain Architecture
Description	HLA class II histocompatibility antigen, DR-1 beta chain precursor (Clone P2-beta-3).

ZN235_MOUSE
NC score	-0.004418 (rank : 1196)	θ value	0.62314 (rank : 409)
Query Neighborhood Hits	600	Target Neighborhood Hits	768	Shared Neighborhood Hits	41
SwissProt Accessions	Q61116, Q3UKA3, Q8CE70	Gene names	Znf235, Zfp93
Domain Architecture
Description	Zinc finger protein 235 (Zinc finger protein 93) (Zfp-93).

ZN11B_HUMAN
NC score	-0.004476 (rank : 1197)	θ value	3.0926 (rank : 490)
Query Neighborhood Hits	600	Target Neighborhood Hits	802	Shared Neighborhood Hits	37
SwissProt Accessions	Q06732, Q86XY8, Q8NDW3	Gene names	ZNF11B
Domain Architecture	No domain graphic available
Description	Zinc finger protein 11B.

ZN287_HUMAN
NC score	-0.004551 (rank : 1198)	θ value	0.0736092 (rank : 353)
Query Neighborhood Hits	600	Target Neighborhood Hits	777	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HBT7	Gene names	ZNF287
Domain Architecture
Description	Zinc finger protein 287.

KR18_HUMAN
NC score	-0.004630 (rank : 1199)	θ value	3.0926 (rank : 478)
Query Neighborhood Hits	600	Target Neighborhood Hits	763	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HCG1, Q96JC5, Q9H7N6	Gene names	KIAA1611
Domain Architecture
Description	Zinc finger protein Kr18 (HKr18).

ZN490_HUMAN
NC score	-0.005260 (rank : 1200)	θ value	1.81305 (rank : 463)
Query Neighborhood Hits	600	Target Neighborhood Hits	754	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ULM2	Gene names	ZNF490, KIAA1198
Domain Architecture
Description	Zinc finger protein 490.

ZN565_HUMAN
NC score	-0.005542 (rank : 1201)	θ value	2.36792 (rank : 471)
Query Neighborhood Hits	600	Target Neighborhood Hits	743	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N9K5, Q6NUS2	Gene names	ZNF565
Domain Architecture	No domain graphic available
Description	Zinc finger protein 565.

ZNF14_HUMAN
NC score	-0.005601 (rank : 1202)	θ value	8.99809 (rank : 600)
Query Neighborhood Hits	600	Target Neighborhood Hits	760	Shared Neighborhood Hits	35
SwissProt Accessions	P17017, Q9ULZ5	Gene names	ZNF14, GIOT4, KOX6
Domain Architecture
Description	Zinc finger protein 14 (Zinc finger protein KOX6) (Gonadotropin- inducible transcription repressor 4) (GIOT-4).

ZFP37_MOUSE
NC score	-0.005873 (rank : 1203)	θ value	5.27518 (rank : 539)
Query Neighborhood Hits	600	Target Neighborhood Hits	906	Shared Neighborhood Hits	34
SwissProt Accessions	P17141, Q62514	Gene names	Zfp37, Zfp-37
Domain Architecture
Description	Zinc finger protein 37 (Zfp-37) (Male germ cell-specific zinc finger protein).

ZN480_HUMAN
NC score	-0.005940 (rank : 1204)	θ value	5.27518 (rank : 542)
Query Neighborhood Hits	600	Target Neighborhood Hits	744	Shared Neighborhood Hits	30
SwissProt Accessions	Q8WV37, Q5JPG9, Q6P0Q4, Q8N1M5	Gene names	ZNF480
Domain Architecture	No domain graphic available
Description	Zinc finger protein 480.

ZN642_HUMAN
NC score	-0.006285 (rank : 1205)	θ value	3.0926 (rank : 493)
Query Neighborhood Hits	600	Target Neighborhood Hits	744	Shared Neighborhood Hits	31
SwissProt Accessions	Q49AA0, Q5SWM5, Q6ZWK8	Gene names	ZNF642
Domain Architecture	No domain graphic available
Description	Zinc finger protein 642.

PRDM5_MOUSE
NC score	-0.006776 (rank : 1206)	θ value	8.99809 (rank : 590)
Query Neighborhood Hits	600	Target Neighborhood Hits	774	Shared Neighborhood Hits	28
SwissProt Accessions	Q9CXE0	Gene names	Prdm5
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 5 (PR domain-containing protein 5).