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Network neighborhood for query Sequence : PTN21_MOUSE

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PTN21_MOUSE
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PTN14_HUMAN
θ value	0 (rank : 1)	NC score	0.992940 (rank : 4)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	104
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	0 (rank : 2)	NC score	0.993568 (rank : 3)
Query Neighborhood Hits	155	Target Neighborhood Hits	142	Shared Neighborhood Hits	107
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN21_HUMAN
θ value	0 (rank : 3)	NC score	0.998301 (rank : 2)
Query Neighborhood Hits	155	Target Neighborhood Hits	143	Shared Neighborhood Hits	118
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	155
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN3_HUMAN
θ value	1.61718e-49 (rank : 5)	NC score	0.930007 (rank : 5)
Query Neighborhood Hits	155	Target Neighborhood Hits	258	Shared Neighborhood Hits	102
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN6_MOUSE
θ value	1.67352e-46 (rank : 6)	NC score	0.754600 (rank : 41)
Query Neighborhood Hits	155	Target Neighborhood Hits	225	Shared Neighborhood Hits	64
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN6_HUMAN
θ value	2.41655e-45 (rank : 7)	NC score	0.756470 (rank : 39)
Query Neighborhood Hits	155	Target Neighborhood Hits	234	Shared Neighborhood Hits	64
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN13_MOUSE
θ value	4.122e-45 (rank : 8)	NC score	0.814867 (rank : 7)
Query Neighborhood Hits	155	Target Neighborhood Hits	426	Shared Neighborhood Hits	107
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN4_HUMAN
θ value	5.38352e-45 (rank : 9)	NC score	0.922410 (rank : 6)
Query Neighborhood Hits	155	Target Neighborhood Hits	303	Shared Neighborhood Hits	104
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN13_HUMAN
θ value	2.26182e-43 (rank : 10)	NC score	0.804840 (rank : 8)
Query Neighborhood Hits	155	Target Neighborhood Hits	471	Shared Neighborhood Hits	105
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTPRD_HUMAN
θ value	5.03882e-43 (rank : 11)	NC score	0.557376 (rank : 78)
Query Neighborhood Hits	155	Target Neighborhood Hits	485	Shared Neighborhood Hits	68
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRS_HUMAN
θ value	2.50074e-42 (rank : 12)	NC score	0.567690 (rank : 75)
Query Neighborhood Hits	155	Target Neighborhood Hits	472	Shared Neighborhood Hits	67
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTN9_HUMAN
θ value	9.50281e-42 (rank : 13)	NC score	0.788091 (rank : 18)
Query Neighborhood Hits	155	Target Neighborhood Hits	79	Shared Neighborhood Hits	62
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	3.61106e-41 (rank : 14)	NC score	0.788057 (rank : 19)
Query Neighborhood Hits	155	Target Neighborhood Hits	78	Shared Neighborhood Hits	62
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

E41L3_HUMAN
θ value	1.79215e-40 (rank : 15)	NC score	0.621864 (rank : 64)
Query Neighborhood Hits	155	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

PTPRD_MOUSE
θ value	1.79215e-40 (rank : 16)	NC score	0.547993 (rank : 82)
Query Neighborhood Hits	155	Target Neighborhood Hits	491	Shared Neighborhood Hits	68
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

E41L3_MOUSE
θ value	3.99248e-40 (rank : 17)	NC score	0.612034 (rank : 70)
Query Neighborhood Hits	155	Target Neighborhood Hits	250	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
θ value	1.98146e-39 (rank : 18)	NC score	0.610349 (rank : 71)
Query Neighborhood Hits	155	Target Neighborhood Hits	287	Shared Neighborhood Hits	51
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
θ value	1.98146e-39 (rank : 19)	NC score	0.595191 (rank : 72)
Query Neighborhood Hits	155	Target Neighborhood Hits	459	Shared Neighborhood Hits	51
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

PTN1_HUMAN
θ value	1.98146e-39 (rank : 20)	NC score	0.800783 (rank : 10)
Query Neighborhood Hits	155	Target Neighborhood Hits	84	Shared Neighborhood Hits	61
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTPRF_HUMAN
θ value	1.98146e-39 (rank : 21)	NC score	0.553403 (rank : 81)
Query Neighborhood Hits	155	Target Neighborhood Hits	489	Shared Neighborhood Hits	67
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTN11_HUMAN
θ value	3.37985e-39 (rank : 22)	NC score	0.733569 (rank : 43)
Query Neighborhood Hits	155	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN1_MOUSE
θ value	3.37985e-39 (rank : 23)	NC score	0.801136 (rank : 9)
Query Neighborhood Hits	155	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN11_MOUSE
θ value	4.41421e-39 (rank : 24)	NC score	0.733508 (rank : 44)
Query Neighborhood Hits	155	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTPRA_HUMAN
θ value	7.52953e-39 (rank : 25)	NC score	0.775944 (rank : 29)
Query Neighborhood Hits	155	Target Neighborhood Hits	101	Shared Neighborhood Hits	65
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

41_HUMAN
θ value	1.6774e-38 (rank : 26)	NC score	0.618461 (rank : 67)
Query Neighborhood Hits	155	Target Neighborhood Hits	157	Shared Neighborhood Hits	50
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

PTPRA_MOUSE
θ value	1.6774e-38 (rank : 27)	NC score	0.775572 (rank : 30)
Query Neighborhood Hits	155	Target Neighborhood Hits	93	Shared Neighborhood Hits	64
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

E41L1_MOUSE
θ value	2.19075e-38 (rank : 28)	NC score	0.618763 (rank : 66)
Query Neighborhood Hits	155	Target Neighborhood Hits	106	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

E41L1_HUMAN
θ value	6.37413e-38 (rank : 29)	NC score	0.615658 (rank : 68)
Query Neighborhood Hits	155	Target Neighborhood Hits	180	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

CD45_HUMAN
θ value	1.42001e-37 (rank : 30)	NC score	0.774007 (rank : 34)
Query Neighborhood Hits	155	Target Neighborhood Hits	243	Shared Neighborhood Hits	68
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	1.42001e-37 (rank : 31)	NC score	0.780557 (rank : 25)
Query Neighborhood Hits	155	Target Neighborhood Hits	178	Shared Neighborhood Hits	68
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

41_MOUSE
θ value	1.85459e-37 (rank : 32)	NC score	0.615193 (rank : 69)
Query Neighborhood Hits	155	Target Neighborhood Hits	184	Shared Neighborhood Hits	52
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

PTPRK_MOUSE
θ value	2.42216e-37 (rank : 33)	NC score	0.720596 (rank : 47)
Query Neighborhood Hits	155	Target Neighborhood Hits	223	Shared Neighborhood Hits	64
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTN2_MOUSE
θ value	4.13158e-37 (rank : 34)	NC score	0.799419 (rank : 11)
Query Neighborhood Hits	155	Target Neighborhood Hits	107	Shared Neighborhood Hits	61
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTPRV_MOUSE
θ value	5.39604e-37 (rank : 35)	NC score	0.752257 (rank : 42)
Query Neighborhood Hits	155	Target Neighborhood Hits	179	Shared Neighborhood Hits	66
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRK_HUMAN
θ value	7.04741e-37 (rank : 36)	NC score	0.722029 (rank : 46)
Query Neighborhood Hits	155	Target Neighborhood Hits	228	Shared Neighborhood Hits	64
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRG_MOUSE
θ value	9.20422e-37 (rank : 37)	NC score	0.698378 (rank : 55)
Query Neighborhood Hits	155	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	9.20422e-37 (rank : 38)	NC score	0.755400 (rank : 40)
Query Neighborhood Hits	155	Target Neighborhood Hits	207	Shared Neighborhood Hits	65
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN22_HUMAN
θ value	1.57e-36 (rank : 39)	NC score	0.790246 (rank : 17)
Query Neighborhood Hits	155	Target Neighborhood Hits	109	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTPRJ_MOUSE
θ value	2.67802e-36 (rank : 40)	NC score	0.758906 (rank : 38)
Query Neighborhood Hits	155	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN2_HUMAN
θ value	4.568e-36 (rank : 41)	NC score	0.798351 (rank : 12)
Query Neighborhood Hits	155	Target Neighborhood Hits	92	Shared Neighborhood Hits	61
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTPRZ_HUMAN
θ value	5.96599e-36 (rank : 42)	NC score	0.701633 (rank : 53)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	64
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_HUMAN
θ value	7.79185e-36 (rank : 43)	NC score	0.700552 (rank : 54)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	65
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRE_MOUSE
θ value	1.73584e-35 (rank : 44)	NC score	0.774134 (rank : 33)
Query Neighborhood Hits	155	Target Neighborhood Hits	86	Shared Neighborhood Hits	64
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRB_HUMAN
θ value	2.26708e-35 (rank : 45)	NC score	0.729330 (rank : 45)
Query Neighborhood Hits	155	Target Neighborhood Hits	242	Shared Neighborhood Hits	67
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTN12_HUMAN
θ value	5.0505e-35 (rank : 46)	NC score	0.787823 (rank : 20)
Query Neighborhood Hits	155	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTPRE_HUMAN
θ value	5.0505e-35 (rank : 47)	NC score	0.774418 (rank : 31)
Query Neighborhood Hits	155	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTN12_MOUSE
θ value	1.9192e-34 (rank : 48)	NC score	0.786961 (rank : 21)
Query Neighborhood Hits	155	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN22_MOUSE
θ value	2.50655e-34 (rank : 49)	NC score	0.783634 (rank : 24)
Query Neighborhood Hits	155	Target Neighborhood Hits	179	Shared Neighborhood Hits	64
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTPRM_MOUSE
θ value	2.50655e-34 (rank : 50)	NC score	0.704634 (rank : 51)
Query Neighborhood Hits	155	Target Neighborhood Hits	238	Shared Neighborhood Hits	67
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRT_HUMAN
θ value	2.50655e-34 (rank : 51)	NC score	0.715495 (rank : 49)
Query Neighborhood Hits	155	Target Neighborhood Hits	217	Shared Neighborhood Hits	64
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	2.50655e-34 (rank : 52)	NC score	0.715496 (rank : 48)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	64
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTN7_HUMAN
θ value	5.584e-34 (rank : 53)	NC score	0.793353 (rank : 16)
Query Neighborhood Hits	155	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTPRM_HUMAN
θ value	7.29293e-34 (rank : 54)	NC score	0.702769 (rank : 52)
Query Neighborhood Hits	155	Target Neighborhood Hits	244	Shared Neighborhood Hits	67
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTN18_HUMAN
θ value	1.24399e-33 (rank : 55)	NC score	0.797878 (rank : 13)
Query Neighborhood Hits	155	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

E41LA_HUMAN
θ value	2.77131e-33 (rank : 56)	NC score	0.627659 (rank : 59)
Query Neighborhood Hits	155	Target Neighborhood Hits	87	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

PTN7_MOUSE
θ value	2.77131e-33 (rank : 57)	NC score	0.793999 (rank : 14)
Query Neighborhood Hits	155	Target Neighborhood Hits	71	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

E41L5_HUMAN
θ value	4.72714e-33 (rank : 58)	NC score	0.626066 (rank : 60)
Query Neighborhood Hits	155	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LA_MOUSE
θ value	8.06329e-33 (rank : 59)	NC score	0.627848 (rank : 58)
Query Neighborhood Hits	155	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

FARP1_HUMAN
θ value	1.37539e-32 (rank : 60)	NC score	0.515959 (rank : 85)
Query Neighborhood Hits	155	Target Neighborhood Hits	241	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

E41LB_MOUSE
θ value	2.34606e-32 (rank : 61)	NC score	0.626061 (rank : 61)
Query Neighborhood Hits	155	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

PTPRO_HUMAN
θ value	3.06405e-32 (rank : 62)	NC score	0.780454 (rank : 27)
Query Neighborhood Hits	155	Target Neighborhood Hits	139	Shared Neighborhood Hits	64
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTN18_MOUSE
θ value	5.22648e-32 (rank : 63)	NC score	0.793576 (rank : 15)
Query Neighborhood Hits	155	Target Neighborhood Hits	134	Shared Neighborhood Hits	62
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN5_MOUSE
θ value	1.16434e-31 (rank : 64)	NC score	0.785227 (rank : 22)
Query Neighborhood Hits	155	Target Neighborhood Hits	85	Shared Neighborhood Hits	64
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRN_MOUSE
θ value	2.59387e-31 (rank : 65)	NC score	0.768338 (rank : 37)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	62
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRR_MOUSE
θ value	2.59387e-31 (rank : 66)	NC score	0.780522 (rank : 26)
Query Neighborhood Hits	155	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRN_HUMAN
θ value	5.77852e-31 (rank : 67)	NC score	0.771675 (rank : 36)
Query Neighborhood Hits	155	Target Neighborhood Hits	156	Shared Neighborhood Hits	63
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

E41LB_HUMAN
θ value	1.28732e-30 (rank : 68)	NC score	0.619690 (rank : 65)
Query Neighborhood Hits	155	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

PTN5_HUMAN
θ value	1.28732e-30 (rank : 69)	NC score	0.784705 (rank : 23)
Query Neighborhood Hits	155	Target Neighborhood Hits	80	Shared Neighborhood Hits	64
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRR_HUMAN
θ value	1.28732e-30 (rank : 70)	NC score	0.779865 (rank : 28)
Query Neighborhood Hits	155	Target Neighborhood Hits	77	Shared Neighborhood Hits	62
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

FARP2_MOUSE
θ value	8.3442e-30 (rank : 71)	NC score	0.495403 (rank : 91)
Query Neighborhood Hits	155	Target Neighborhood Hits	209	Shared Neighborhood Hits	46
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

FARP2_HUMAN
θ value	1.85889e-29 (rank : 72)	NC score	0.499246 (rank : 89)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	46
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

MOES_HUMAN
θ value	2.05525e-28 (rank : 73)	NC score	0.467719 (rank : 95)
Query Neighborhood Hits	155	Target Neighborhood Hits	892	Shared Neighborhood Hits	55
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

FRMD5_HUMAN
θ value	3.50572e-28 (rank : 74)	NC score	0.623583 (rank : 63)
Query Neighborhood Hits	155	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

MOES_MOUSE
θ value	3.50572e-28 (rank : 75)	NC score	0.462354 (rank : 96)
Query Neighborhood Hits	155	Target Neighborhood Hits	923	Shared Neighborhood Hits	56
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

PTPR2_MOUSE
θ value	3.50572e-28 (rank : 76)	NC score	0.773094 (rank : 35)
Query Neighborhood Hits	155	Target Neighborhood Hits	120	Shared Neighborhood Hits	62
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

FRMD5_MOUSE
θ value	4.57862e-28 (rank : 77)	NC score	0.624891 (rank : 62)
Query Neighborhood Hits	155	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

PTPR2_HUMAN
θ value	5.97985e-28 (rank : 78)	NC score	0.774354 (rank : 32)
Query Neighborhood Hits	155	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTN23_HUMAN
θ value	1.33217e-27 (rank : 79)	NC score	0.683368 (rank : 56)
Query Neighborhood Hits	155	Target Neighborhood Hits	646	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

EZRI_HUMAN
θ value	2.27234e-27 (rank : 80)	NC score	0.509815 (rank : 86)
Query Neighborhood Hits	155	Target Neighborhood Hits	663	Shared Neighborhood Hits	53
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

PTN23_MOUSE
θ value	2.96777e-27 (rank : 81)	NC score	0.681627 (rank : 57)
Query Neighborhood Hits	155	Target Neighborhood Hits	726	Shared Neighborhood Hits	71
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

EZRI_MOUSE
θ value	3.87602e-27 (rank : 82)	NC score	0.506409 (rank : 87)
Query Neighborhood Hits	155	Target Neighborhood Hits	693	Shared Neighborhood Hits	55
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

PTPRU_HUMAN
θ value	5.06226e-27 (rank : 83)	NC score	0.706876 (rank : 50)
Query Neighborhood Hits	155	Target Neighborhood Hits	237	Shared Neighborhood Hits	66
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

MERL_HUMAN
θ value	6.61148e-27 (rank : 84)	NC score	0.539243 (rank : 84)
Query Neighborhood Hits	155	Target Neighborhood Hits	532	Shared Neighborhood Hits	56
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

RADI_HUMAN
θ value	6.61148e-27 (rank : 85)	NC score	0.497901 (rank : 90)
Query Neighborhood Hits	155	Target Neighborhood Hits	741	Shared Neighborhood Hits	55
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

RADI_MOUSE
θ value	6.61148e-27 (rank : 86)	NC score	0.495123 (rank : 92)
Query Neighborhood Hits	155	Target Neighborhood Hits	773	Shared Neighborhood Hits	54
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

MERL_MOUSE
θ value	8.63488e-27 (rank : 87)	NC score	0.539669 (rank : 83)
Query Neighborhood Hits	155	Target Neighborhood Hits	524	Shared Neighborhood Hits	56
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

FRM4B_MOUSE
θ value	1.99067e-23 (rank : 88)	NC score	0.565420 (rank : 76)
Query Neighborhood Hits	155	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4B_HUMAN
θ value	2.20094e-22 (rank : 89)	NC score	0.564452 (rank : 77)
Query Neighborhood Hits	155	Target Neighborhood Hits	117	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

FRM4A_MOUSE
θ value	6.40375e-22 (rank : 90)	NC score	0.555796 (rank : 80)
Query Neighborhood Hits	155	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_HUMAN
θ value	1.09232e-21 (rank : 91)	NC score	0.556769 (rank : 79)
Query Neighborhood Hits	155	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

MYLIP_MOUSE
θ value	1.86321e-21 (rank : 92)	NC score	0.586197 (rank : 73)
Query Neighborhood Hits	155	Target Neighborhood Hits	139	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
θ value	1.33526e-19 (rank : 93)	NC score	0.571550 (rank : 74)
Query Neighborhood Hits	155	Target Neighborhood Hits	162	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

FRMD6_MOUSE
θ value	2.28291e-11 (rank : 94)	NC score	0.501040 (rank : 88)
Query Neighborhood Hits	155	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FRMD6_HUMAN
θ value	1.25267e-09 (rank : 95)	NC score	0.493628 (rank : 93)
Query Neighborhood Hits	155	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD1_HUMAN
θ value	6.21693e-09 (rank : 96)	NC score	0.490472 (rank : 94)
Query Neighborhood Hits	155	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

TLN1_HUMAN
θ value	0.000270298 (rank : 97)	NC score	0.261582 (rank : 97)
Query Neighborhood Hits	155	Target Neighborhood Hits	218	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
θ value	0.000270298 (rank : 98)	NC score	0.259267 (rank : 98)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	47
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

L2GL1_MOUSE
θ value	0.00390308 (rank : 99)	NC score	0.021273 (rank : 184)
Query Neighborhood Hits	155	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q80Y17, Q61856, Q7TNV3, Q8BN92	Gene names	Llgl1, Llglh
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Mlgl) (Mgl-1).

TLN2_HUMAN
θ value	0.00869519 (rank : 100)	NC score	0.250047 (rank : 100)
Query Neighborhood Hits	155	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

TLN2_MOUSE
θ value	0.0148317 (rank : 101)	NC score	0.254122 (rank : 99)
Query Neighborhood Hits	155	Target Neighborhood Hits	149	Shared Neighborhood Hits	53
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

K1024_HUMAN
θ value	0.0431538 (rank : 102)	NC score	0.022189 (rank : 183)
Query Neighborhood Hits	155	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPX6	Gene names	KIAA1024
Domain Architecture
Description	UPF0258 protein KIAA1024.

MYO10_HUMAN
θ value	0.0961366 (rank : 103)	NC score	0.022772 (rank : 181)
Query Neighborhood Hits	155	Target Neighborhood Hits	920	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

FRAT1_HUMAN
θ value	0.21417 (rank : 104)	NC score	0.027989 (rank : 180)
Query Neighborhood Hits	155	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q92837, Q8NE74, Q8TDW9	Gene names	FRAT1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

AP2B_HUMAN
θ value	0.365318 (rank : 105)	NC score	0.016351 (rank : 189)
Query Neighborhood Hits	155	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
θ value	0.365318 (rank : 106)	NC score	0.016334 (rank : 190)
Query Neighborhood Hits	155	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

MLL3_MOUSE
θ value	0.365318 (rank : 107)	NC score	0.017958 (rank : 186)
Query Neighborhood Hits	155	Target Neighborhood Hits	1399	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SETX_HUMAN
θ value	0.47712 (rank : 108)	NC score	0.019384 (rank : 185)
Query Neighborhood Hits	155	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

MYO7A_MOUSE
θ value	0.813845 (rank : 109)	NC score	0.038889 (rank : 176)
Query Neighborhood Hits	155	Target Neighborhood Hits	235	Shared Neighborhood Hits	28
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

SMAD2_HUMAN
θ value	0.813845 (rank : 110)	NC score	0.011370 (rank : 194)
Query Neighborhood Hits	155	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q15796	Gene names	SMAD2, MADH2, MADR2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (hMAD-2) (JV18-1) (hSMAD2).

SMAD2_MOUSE
θ value	0.813845 (rank : 111)	NC score	0.011371 (rank : 193)
Query Neighborhood Hits	155	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q62432, Q9D8P6	Gene names	Smad2, Madh2, Madr2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2).

AKAP6_HUMAN
θ value	1.06291 (rank : 112)	NC score	0.010430 (rank : 195)
Query Neighborhood Hits	155	Target Neighborhood Hits	263	Shared Neighborhood Hits	9
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

MYO7A_HUMAN
θ value	1.06291 (rank : 113)	NC score	0.038672 (rank : 177)
Query Neighborhood Hits	155	Target Neighborhood Hits	209	Shared Neighborhood Hits	30
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

TCF7_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.009373 (rank : 198)
Query Neighborhood Hits	155	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

AAT1_HUMAN
θ value	1.81305 (rank : 115)	NC score	0.010284 (rank : 196)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

AKAP2_MOUSE
θ value	1.81305 (rank : 116)	NC score	0.010100 (rank : 197)
Query Neighborhood Hits	155	Target Neighborhood Hits	385	Shared Neighborhood Hits	9
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CN037_HUMAN
θ value	1.81305 (rank : 117)	NC score	0.017630 (rank : 187)
Query Neighborhood Hits	155	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

FA5_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.006278 (rank : 204)
Query Neighborhood Hits	155	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

LIPA1_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.013604 (rank : 192)
Query Neighborhood Hits	155	Target Neighborhood Hits	1294	Shared Neighborhood Hits	21
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

ARI1A_HUMAN
θ value	2.36792 (rank : 120)	NC score	0.005627 (rank : 207)
Query Neighborhood Hits	155	Target Neighborhood Hits	787	Shared Neighborhood Hits	15
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

EP300_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.006884 (rank : 203)
Query Neighborhood Hits	155	Target Neighborhood Hits	821	Shared Neighborhood Hits	12
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

US6NL_MOUSE
θ value	2.36792 (rank : 122)	NC score	0.016858 (rank : 188)
Query Neighborhood Hits	155	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

MYPN_HUMAN
θ value	3.0926 (rank : 123)	NC score	0.031383 (rank : 179)
Query Neighborhood Hits	155	Target Neighborhood Hits	418	Shared Neighborhood Hits	11
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

PRP4B_HUMAN
θ value	3.0926 (rank : 124)	NC score	-0.005745 (rank : 221)
Query Neighborhood Hits	155	Target Neighborhood Hits	1030	Shared Neighborhood Hits	10
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

MLH1_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.006118 (rank : 205)
Query Neighborhood Hits	155	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P40692	Gene names	MLH1, COCA2
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

PTEN_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.082935 (rank : 114)
Query Neighborhood Hits	155	Target Neighborhood Hits	72	Shared Neighborhood Hits	30
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.082934 (rank : 115)
Query Neighborhood Hits	155	Target Neighborhood Hits	73	Shared Neighborhood Hits	30
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

TITIN_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.035852 (rank : 178)
Query Neighborhood Hits	155	Target Neighborhood Hits	2923	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TP53B_HUMAN
θ value	4.03905 (rank : 129)	NC score	0.015437 (rank : 191)
Query Neighborhood Hits	155	Target Neighborhood Hits	413	Shared Neighborhood Hits	16
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ANR26_MOUSE
θ value	5.27518 (rank : 130)	NC score	0.007492 (rank : 201)
Query Neighborhood Hits	155	Target Neighborhood Hits	1554	Shared Neighborhood Hits	22
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

COIA1_HUMAN
θ value	5.27518 (rank : 131)	NC score	-0.000150 (rank : 218)
Query Neighborhood Hits	155	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

MYNN_HUMAN
θ value	5.27518 (rank : 132)	NC score	-0.008982 (rank : 225)
Query Neighborhood Hits	155	Target Neighborhood Hits	826	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPC7, Q6QHA6, Q6QHA7, Q6R3G1, Q6R3G2, Q6R4A0, Q7Z716, Q7Z717, Q86Z11, Q86Z12, Q9NS01, Q9UIW8	Gene names	MYNN, OSZF, ZBTB31
Domain Architecture	No domain graphic available
Description	Myoneurin (Zinc finger and BTB domain-containing protein 31).

PRP4B_MOUSE
θ value	5.27518 (rank : 133)	NC score	-0.006400 (rank : 222)
Query Neighborhood Hits	155	Target Neighborhood Hits	1040	Shared Neighborhood Hits	9
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

SSH2_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.005979 (rank : 206)
Query Neighborhood Hits	155	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

SSH2_MOUSE
θ value	5.27518 (rank : 135)	NC score	0.003529 (rank : 212)
Query Neighborhood Hits	155	Target Neighborhood Hits	119	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

ACES_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.000899 (rank : 217)
Query Neighborhood Hits	155	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

AFAD_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.022442 (rank : 182)
Query Neighborhood Hits	155	Target Neighborhood Hits	689	Shared Neighborhood Hits	15
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

BRCA1_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.002414 (rank : 214)
Query Neighborhood Hits	155	Target Neighborhood Hits	436	Shared Neighborhood Hits	10
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

IMPG1_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.005135 (rank : 209)
Query Neighborhood Hits	155	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

K0494_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.001828 (rank : 216)
Query Neighborhood Hits	155	Target Neighborhood Hits	230	Shared Neighborhood Hits	4
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

KRIT1_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.059070 (rank : 150)
Query Neighborhood Hits	155	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

NU205_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.006934 (rank : 202)
Query Neighborhood Hits	155	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).

PAPPA_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.004708 (rank : 210)
Query Neighborhood Hits	155	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

RIF1_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.005376 (rank : 208)
Query Neighborhood Hits	155	Target Neighborhood Hits	320	Shared Neighborhood Hits	7
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

RIN2_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.003194 (rank : 213)
Query Neighborhood Hits	155	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

SMAD3_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.008597 (rank : 199)
Query Neighborhood Hits	155	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	P84022, O09064, O09144, O14510, O35273, Q92940, Q93002, Q9GKR4	Gene names	SMAD3, MADH3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (hMAD-3) (JV15-2) (hSMAD3).

SMAD3_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.008597 (rank : 200)
Query Neighborhood Hits	155	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BUN5, O09064, O09144, O14510, O35273, Q8BX84, Q92940, Q93002, Q9GKR4	Gene names	Smad3, Madh3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (mMad3).

TENR_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.065444 (rank : 136)
Query Neighborhood Hits	155	Target Neighborhood Hits	531	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

CC14B_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.106097 (rank : 105)
Query Neighborhood Hits	155	Target Neighborhood Hits	114	Shared Neighborhood Hits	53
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CD2L6_HUMAN
θ value	8.99809 (rank : 150)	NC score	-0.007173 (rank : 223)
Query Neighborhood Hits	155	Target Neighborhood Hits	844	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWU1, Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2	Gene names	CDC2L6, CDK11, KIAA1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11).

CD2L6_MOUSE
θ value	8.99809 (rank : 151)	NC score	-0.007183 (rank : 224)
Query Neighborhood Hits	155	Target Neighborhood Hits	851	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

DMRT1_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.004242 (rank : 211)
Query Neighborhood Hits	155	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ59, Q9QZ37, Q9QZA4	Gene names	Dmrt1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1.

PARVA_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.001888 (rank : 215)
Query Neighborhood Hits	155	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVD7, Q96C85, Q9HA48	Gene names	PARVA
Domain Architecture
Description	Alpha-parvin (Calponin-like integrin-linked kinase-binding protein) (CH-ILKBP).

REM1_MOUSE
θ value	8.99809 (rank : 154)	NC score	-0.003511 (rank : 220)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	2
SwissProt Accessions	O35929	Gene names	Rem1, Rem
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1).

STF1_HUMAN
θ value	8.99809 (rank : 155)	NC score	-0.001798 (rank : 219)
Query Neighborhood Hits	155	Target Neighborhood Hits	132	Shared Neighborhood Hits	2
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

CA106_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.070092 (rank : 126)
Query Neighborhood Hits	155	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

CA106_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.068986 (rank : 130)
Query Neighborhood Hits	155	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

CC14A_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.091721 (rank : 110)
Query Neighborhood Hits	155	Target Neighborhood Hits	133	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.094506 (rank : 109)
Query Neighborhood Hits	155	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14B_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.103394 (rank : 106)
Query Neighborhood Hits	155	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CDKN3_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.061618 (rank : 144)
Query Neighborhood Hits	155	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

CNTN1_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.054039 (rank : 165)
Query Neighborhood Hits	155	Target Neighborhood Hits	431	Shared Neighborhood Hits	15
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

CNTN1_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.055164 (rank : 160)
Query Neighborhood Hits	155	Target Neighborhood Hits	422	Shared Neighborhood Hits	15
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN2_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.058065 (rank : 152)
Query Neighborhood Hits	155	Target Neighborhood Hits	440	Shared Neighborhood Hits	16
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN2_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.057935 (rank : 154)
Query Neighborhood Hits	155	Target Neighborhood Hits	450	Shared Neighborhood Hits	16
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN3_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.051024 (rank : 173)
Query Neighborhood Hits	155	Target Neighborhood Hits	455	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN3_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.053194 (rank : 167)
Query Neighborhood Hits	155	Target Neighborhood Hits	447	Shared Neighborhood Hits	19
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN5_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.059756 (rank : 147)
Query Neighborhood Hits	155	Target Neighborhood Hits	446	Shared Neighborhood Hits	19
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

CNTN5_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.058399 (rank : 151)
Query Neighborhood Hits	155	Target Neighborhood Hits	434	Shared Neighborhood Hits	17
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CNTN6_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.052460 (rank : 168)
Query Neighborhood Hits	155	Target Neighborhood Hits	422	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CO7A1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.057537 (rank : 155)
Query Neighborhood Hits	155	Target Neighborhood Hits	807	Shared Neighborhood Hits	22
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

COCA1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.072556 (rank : 121)
Query Neighborhood Hits	155	Target Neighborhood Hits	458	Shared Neighborhood Hits	27
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.073990 (rank : 120)
Query Neighborhood Hits	155	Target Neighborhood Hits	467	Shared Neighborhood Hits	23
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.054479 (rank : 163)
Query Neighborhood Hits	155	Target Neighborhood Hits	427	Shared Neighborhood Hits	19
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.061140 (rank : 145)
Query Neighborhood Hits	155	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

DCC_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.083878 (rank : 113)
Query Neighborhood Hits	155	Target Neighborhood Hits	583	Shared Neighborhood Hits	26
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.081026 (rank : 117)
Query Neighborhood Hits	155	Target Neighborhood Hits	896	Shared Neighborhood Hits	29
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DSCAM_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.062035 (rank : 141)
Query Neighborhood Hits	155	Target Neighborhood Hits	524	Shared Neighborhood Hits	20
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.062035 (rank : 142)
Query Neighborhood Hits	155	Target Neighborhood Hits	589	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

DUS23_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.209048 (rank : 102)
Query Neighborhood Hits	155	Target Neighborhood Hits	98	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

DUS23_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.218523 (rank : 101)
Query Neighborhood Hits	155	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

FINC_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.111445 (rank : 103)
Query Neighborhood Hits	155	Target Neighborhood Hits	302	Shared Neighborhood Hits	22
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.110631 (rank : 104)
Query Neighborhood Hits	155	Target Neighborhood Hits	309	Shared Neighborhood Hits	22
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FNDC3_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.100963 (rank : 107)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.094676 (rank : 108)
Query Neighborhood Hits	155	Target Neighborhood Hits	207	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

ITB4_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.064667 (rank : 138)
Query Neighborhood Hits	155	Target Neighborhood Hits	458	Shared Neighborhood Hits	19
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KRIT1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.059440 (rank : 149)
Query Neighborhood Hits	155	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

L1CAM_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.062073 (rank : 140)
Query Neighborhood Hits	155	Target Neighborhood Hits	457	Shared Neighborhood Hits	18
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.062854 (rank : 139)
Query Neighborhood Hits	155	Target Neighborhood Hits	457	Shared Neighborhood Hits	23
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

LIFR_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.051192 (rank : 172)
Query Neighborhood Hits	155	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

MAMC1_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.055128 (rank : 161)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.056113 (rank : 159)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.069437 (rank : 128)
Query Neighborhood Hits	155	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.072386 (rank : 122)
Query Neighborhood Hits	155	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MDGA1_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.058052 (rank : 153)
Query Neighborhood Hits	155	Target Neighborhood Hits	358	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MYOM1_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.053720 (rank : 166)
Query Neighborhood Hits	155	Target Neighborhood Hits	405	Shared Neighborhood Hits	15
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

MYOM1_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.057073 (rank : 157)
Query Neighborhood Hits	155	Target Neighborhood Hits	415	Shared Neighborhood Hits	18
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

MYOM2_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.050279 (rank : 174)
Query Neighborhood Hits	155	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

NEO1_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.079534 (rank : 118)
Query Neighborhood Hits	155	Target Neighborhood Hits	530	Shared Neighborhood Hits	25
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.081876 (rank : 116)
Query Neighborhood Hits	155	Target Neighborhood Hits	523	Shared Neighborhood Hits	25
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NFASC_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.054412 (rank : 164)
Query Neighborhood Hits	155	Target Neighborhood Hits	497	Shared Neighborhood Hits	17
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

NFASC_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.052172 (rank : 170)
Query Neighborhood Hits	155	Target Neighborhood Hits	475	Shared Neighborhood Hits	17
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

NRCAM_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.059932 (rank : 146)
Query Neighborhood Hits	155	Target Neighborhood Hits	439	Shared Neighborhood Hits	16
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

NRCAM_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.061890 (rank : 143)
Query Neighborhood Hits	155	Target Neighborhood Hits	432	Shared Neighborhood Hits	18
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

PUNC_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.052323 (rank : 169)
Query Neighborhood Hits	155	Target Neighborhood Hits	449	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

RES18_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.056520 (rank : 158)
Query Neighborhood Hits	155	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

ROBO3_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.051719 (rank : 171)
Query Neighborhood Hits	155	Target Neighborhood Hits	524	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

SDK1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.067878 (rank : 132)
Query Neighborhood Hits	155	Target Neighborhood Hits	511	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.069038 (rank : 129)
Query Neighborhood Hits	155	Target Neighborhood Hits	495	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.068719 (rank : 131)
Query Neighborhood Hits	155	Target Neighborhood Hits	495	Shared Neighborhood Hits	21
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.071435 (rank : 123)
Query Neighborhood Hits	155	Target Neighborhood Hits	480	Shared Neighborhood Hits	21
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

TARSH_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.057079 (rank : 156)
Query Neighborhood Hits	155	Target Neighborhood Hits	768	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TENA_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.054940 (rank : 162)
Query Neighborhood Hits	155	Target Neighborhood Hits	631	Shared Neighborhood Hits	22
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.050101 (rank : 175)
Query Neighborhood Hits	155	Target Neighborhood Hits	596	Shared Neighborhood Hits	19
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.066205 (rank : 135)
Query Neighborhood Hits	155	Target Neighborhood Hits	453	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.077158 (rank : 119)
Query Neighborhood Hits	155	Target Neighborhood Hits	484	Shared Neighborhood Hits	20
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.065138 (rank : 137)
Query Neighborhood Hits	155	Target Neighborhood Hits	526	Shared Neighborhood Hits	19
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TP4A1_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.086393 (rank : 111)
Query Neighborhood Hits	155	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.086393 (rank : 112)
Query Neighborhood Hits	155	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

TP4A2_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.070266 (rank : 124)
Query Neighborhood Hits	155	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.070266 (rank : 125)
Query Neighborhood Hits	155	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

TP4A3_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.067025 (rank : 133)
Query Neighborhood Hits	155	Target Neighborhood Hits	62	Shared Neighborhood Hits	26
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.059660 (rank : 148)
Query Neighborhood Hits	155	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

USH2A_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.069591 (rank : 127)
Query Neighborhood Hits	155	Target Neighborhood Hits	600	Shared Neighborhood Hits	28
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.066515 (rank : 134)
Query Neighborhood Hits	155	Target Neighborhood Hits	626	Shared Neighborhood Hits	24
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

Hits sorted by NC score

PTN21_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	155
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
NC score	0.998301 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	155	Target Neighborhood Hits	143	Shared Neighborhood Hits	118
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN14_MOUSE
NC score	0.993568 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	155	Target Neighborhood Hits	142	Shared Neighborhood Hits	107
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN14_HUMAN
NC score	0.992940 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	104
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN3_HUMAN
NC score	0.930007 (rank : 5)	θ value	1.61718e-49 (rank : 5)
Query Neighborhood Hits	155	Target Neighborhood Hits	258	Shared Neighborhood Hits	102
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
NC score	0.922410 (rank : 6)	θ value	5.38352e-45 (rank : 9)
Query Neighborhood Hits	155	Target Neighborhood Hits	303	Shared Neighborhood Hits	104
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN13_MOUSE
NC score	0.814867 (rank : 7)	θ value	4.122e-45 (rank : 8)
Query Neighborhood Hits	155	Target Neighborhood Hits	426	Shared Neighborhood Hits	107
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN13_HUMAN
NC score	0.804840 (rank : 8)	θ value	2.26182e-43 (rank : 10)
Query Neighborhood Hits	155	Target Neighborhood Hits	471	Shared Neighborhood Hits	105
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN1_MOUSE
NC score	0.801136 (rank : 9)	θ value	3.37985e-39 (rank : 23)
Query Neighborhood Hits	155	Target Neighborhood Hits	85	Shared Neighborhood Hits	62
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN1_HUMAN
NC score	0.800783 (rank : 10)	θ value	1.98146e-39 (rank : 20)
Query Neighborhood Hits	155	Target Neighborhood Hits	84	Shared Neighborhood Hits	61
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN2_MOUSE
NC score	0.799419 (rank : 11)	θ value	4.13158e-37 (rank : 34)
Query Neighborhood Hits	155	Target Neighborhood Hits	107	Shared Neighborhood Hits	61
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN2_HUMAN
NC score	0.798351 (rank : 12)	θ value	4.568e-36 (rank : 41)
Query Neighborhood Hits	155	Target Neighborhood Hits	92	Shared Neighborhood Hits	61
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN18_HUMAN
NC score	0.797878 (rank : 13)	θ value	1.24399e-33 (rank : 55)
Query Neighborhood Hits	155	Target Neighborhood Hits	73	Shared Neighborhood Hits	62
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN7_MOUSE
NC score	0.793999 (rank : 14)	θ value	2.77131e-33 (rank : 57)
Query Neighborhood Hits	155	Target Neighborhood Hits	71	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN18_MOUSE
NC score	0.793576 (rank : 15)	θ value	5.22648e-32 (rank : 63)
Query Neighborhood Hits	155	Target Neighborhood Hits	134	Shared Neighborhood Hits	62
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN7_HUMAN
NC score	0.793353 (rank : 16)	θ value	5.584e-34 (rank : 53)
Query Neighborhood Hits	155	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN22_HUMAN
NC score	0.790246 (rank : 17)	θ value	1.57e-36 (rank : 39)
Query Neighborhood Hits	155	Target Neighborhood Hits	109	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN9_HUMAN
NC score	0.788091 (rank : 18)	θ value	9.50281e-42 (rank : 13)
Query Neighborhood Hits	155	Target Neighborhood Hits	79	Shared Neighborhood Hits	62
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
NC score	0.788057 (rank : 19)	θ value	3.61106e-41 (rank : 14)
Query Neighborhood Hits	155	Target Neighborhood Hits	78	Shared Neighborhood Hits	62
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN12_HUMAN
NC score	0.787823 (rank : 20)	θ value	5.0505e-35 (rank : 46)
Query Neighborhood Hits	155	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
NC score	0.786961 (rank : 21)	θ value	1.9192e-34 (rank : 48)
Query Neighborhood Hits	155	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN5_MOUSE
NC score	0.785227 (rank : 22)	θ value	1.16434e-31 (rank : 64)
Query Neighborhood Hits	155	Target Neighborhood Hits	85	Shared Neighborhood Hits	64
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.784705 (rank : 23)	θ value	1.28732e-30 (rank : 69)
Query Neighborhood Hits	155	Target Neighborhood Hits	80	Shared Neighborhood Hits	64
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN22_MOUSE
NC score	0.783634 (rank : 24)	θ value	2.50655e-34 (rank : 49)
Query Neighborhood Hits	155	Target Neighborhood Hits	179	Shared Neighborhood Hits	64
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

CD45_MOUSE
NC score	0.780557 (rank : 25)	θ value	1.42001e-37 (rank : 31)
Query Neighborhood Hits	155	Target Neighborhood Hits	178	Shared Neighborhood Hits	68
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPRR_MOUSE
NC score	0.780522 (rank : 26)	θ value	2.59387e-31 (rank : 66)
Query Neighborhood Hits	155	Target Neighborhood Hits	84	Shared Neighborhood Hits	62
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRO_HUMAN
NC score	0.780454 (rank : 27)	θ value	3.06405e-32 (rank : 62)
Query Neighborhood Hits	155	Target Neighborhood Hits	139	Shared Neighborhood Hits	64
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
NC score	0.779865 (rank : 28)	θ value	1.28732e-30 (rank : 70)
Query Neighborhood Hits	155	Target Neighborhood Hits	77	Shared Neighborhood Hits	62
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRA_HUMAN
NC score	0.775944 (rank : 29)	θ value	7.52953e-39 (rank : 25)
Query Neighborhood Hits	155	Target Neighborhood Hits	101	Shared Neighborhood Hits	65
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
NC score	0.775572 (rank : 30)	θ value	1.6774e-38 (rank : 27)
Query Neighborhood Hits	155	Target Neighborhood Hits	93	Shared Neighborhood Hits	64
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_HUMAN
NC score	0.774418 (rank : 31)	θ value	5.0505e-35 (rank : 47)
Query Neighborhood Hits	155	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPR2_HUMAN
NC score	0.774354 (rank : 32)	θ value	5.97985e-28 (rank : 78)
Query Neighborhood Hits	155	Target Neighborhood Hits	103	Shared Neighborhood Hits	62
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPRE_MOUSE
NC score	0.774134 (rank : 33)	θ value	1.73584e-35 (rank : 44)
Query Neighborhood Hits	155	Target Neighborhood Hits	86	Shared Neighborhood Hits	64
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

CD45_HUMAN
NC score	0.774007 (rank : 34)	θ value	1.42001e-37 (rank : 30)
Query Neighborhood Hits	155	Target Neighborhood Hits	243	Shared Neighborhood Hits	68
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PTPR2_MOUSE
NC score	0.773094 (rank : 35)	θ value	3.50572e-28 (rank : 76)
Query Neighborhood Hits	155	Target Neighborhood Hits	120	Shared Neighborhood Hits	62
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRN_HUMAN
NC score	0.771675 (rank : 36)	θ value	5.77852e-31 (rank : 67)
Query Neighborhood Hits	155	Target Neighborhood Hits	156	Shared Neighborhood Hits	63
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
NC score	0.768338 (rank : 37)	θ value	2.59387e-31 (rank : 65)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	62
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRJ_MOUSE
NC score	0.758906 (rank : 38)	θ value	2.67802e-36 (rank : 40)
Query Neighborhood Hits	155	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTN6_HUMAN
NC score	0.756470 (rank : 39)	θ value	2.41655e-45 (rank : 7)
Query Neighborhood Hits	155	Target Neighborhood Hits	234	Shared Neighborhood Hits	64
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTPRJ_HUMAN
NC score	0.755400 (rank : 40)	θ value	9.20422e-37 (rank : 38)
Query Neighborhood Hits	155	Target Neighborhood Hits	207	Shared Neighborhood Hits	65
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN6_MOUSE
NC score	0.754600 (rank : 41)	θ value	1.67352e-46 (rank : 6)
Query Neighborhood Hits	155	Target Neighborhood Hits	225	Shared Neighborhood Hits	64
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTPRV_MOUSE
NC score	0.752257 (rank : 42)	θ value	5.39604e-37 (rank : 35)
Query Neighborhood Hits	155	Target Neighborhood Hits	179	Shared Neighborhood Hits	66
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN11_HUMAN
NC score	0.733569 (rank : 43)	θ value	3.37985e-39 (rank : 22)
Query Neighborhood Hits	155	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.733508 (rank : 44)	θ value	4.41421e-39 (rank : 24)
Query Neighborhood Hits	155	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTPRB_HUMAN
NC score	0.729330 (rank : 45)	θ value	2.26708e-35 (rank : 45)
Query Neighborhood Hits	155	Target Neighborhood Hits	242	Shared Neighborhood Hits	67
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRK_HUMAN
NC score	0.722029 (rank : 46)	θ value	7.04741e-37 (rank : 36)
Query Neighborhood Hits	155	Target Neighborhood Hits	228	Shared Neighborhood Hits	64
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
NC score	0.720596 (rank : 47)	θ value	2.42216e-37 (rank : 33)
Query Neighborhood Hits	155	Target Neighborhood Hits	223	Shared Neighborhood Hits	64
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRT_MOUSE
NC score	0.715496 (rank : 48)	θ value	2.50655e-34 (rank : 52)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	64
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.715495 (rank : 49)	θ value	2.50655e-34 (rank : 51)
Query Neighborhood Hits	155	Target Neighborhood Hits	217	Shared Neighborhood Hits	64
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRU_HUMAN
NC score	0.706876 (rank : 50)	θ value	5.06226e-27 (rank : 83)
Query Neighborhood Hits	155	Target Neighborhood Hits	237	Shared Neighborhood Hits	66
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTPRM_MOUSE
NC score	0.704634 (rank : 51)	θ value	2.50655e-34 (rank : 50)
Query Neighborhood Hits	155	Target Neighborhood Hits	238	Shared Neighborhood Hits	67
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.702769 (rank : 52)	θ value	7.29293e-34 (rank : 54)
Query Neighborhood Hits	155	Target Neighborhood Hits	244	Shared Neighborhood Hits	67
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRZ_HUMAN
NC score	0.701633 (rank : 53)	θ value	5.96599e-36 (rank : 42)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	64
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTPRG_HUMAN
NC score	0.700552 (rank : 54)	θ value	7.79185e-36 (rank : 43)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	65
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
NC score	0.698378 (rank : 55)	θ value	9.20422e-37 (rank : 37)
Query Neighborhood Hits	155	Target Neighborhood Hits	260	Shared Neighborhood Hits	67
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTN23_HUMAN
NC score	0.683368 (rank : 56)	θ value	1.33217e-27 (rank : 79)
Query Neighborhood Hits	155	Target Neighborhood Hits	646	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
NC score	0.681627 (rank : 57)	θ value	2.96777e-27 (rank : 81)
Query Neighborhood Hits	155	Target Neighborhood Hits	726	Shared Neighborhood Hits	71
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

E41LA_MOUSE
NC score	0.627848 (rank : 58)	θ value	8.06329e-33 (rank : 59)
Query Neighborhood Hits	155	Target Neighborhood Hits	85	Shared Neighborhood Hits	47
SwissProt Accessions	P52963	Gene names	Epb41l4a, Epb4.1l4, Epb4.1l4a, Epb41l4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41LA_HUMAN
NC score	0.627659 (rank : 59)	θ value	2.77131e-33 (rank : 56)
Query Neighborhood Hits	155	Target Neighborhood Hits	87	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCS5	Gene names	EPB41L4A, EPB41L4
Domain Architecture
Description	Band 4.1-like protein 4A (Protein NBL4).

E41L5_HUMAN
NC score	0.626066 (rank : 60)	θ value	4.72714e-33 (rank : 58)
Query Neighborhood Hits	155	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HCM4, Q9H975	Gene names	EPB41L5, KIAA1548
Domain Architecture
Description	Band 4.1-like protein 5.

E41LB_MOUSE
NC score	0.626061 (rank : 61)	θ value	2.34606e-32 (rank : 61)
Query Neighborhood Hits	155	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JMC8	Gene names	Epb41l4b, Ehm2, Epb4.1l4b
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2).

FRMD5_MOUSE
NC score	0.624891 (rank : 62)	θ value	4.57862e-28 (rank : 77)
Query Neighborhood Hits	155	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q6P5H6, Q6PFH6, Q8C0K0	Gene names	Frmd5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

FRMD5_HUMAN
NC score	0.623583 (rank : 63)	θ value	3.50572e-28 (rank : 74)
Query Neighborhood Hits	155	Target Neighborhood Hits	55	Shared Neighborhood Hits	47
SwissProt Accessions	Q7Z6J6, Q8NBG4	Gene names	FRMD5
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 5.

E41L3_HUMAN
NC score	0.621864 (rank : 64)	θ value	1.79215e-40 (rank : 15)
Query Neighborhood Hits	155	Target Neighborhood Hits	113	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y2J2, O95713, Q9BRP5	Gene names	EPB41L3, DAL1, KIAA0987
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1).

E41LB_HUMAN
NC score	0.619690 (rank : 65)	θ value	1.28732e-30 (rank : 68)
Query Neighborhood Hits	155	Target Neighborhood Hits	79	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H329, Q9H328, Q9P2V3	Gene names	EPB41L4B, EHM2
Domain Architecture
Description	Band 4.1-like protein 4B (Protein EHM2) (FERM-containing protein CG1).

E41L1_MOUSE
NC score	0.618763 (rank : 66)	θ value	2.19075e-38 (rank : 28)
Query Neighborhood Hits	155	Target Neighborhood Hits	106	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z2H5	Gene names	Epb41l1, Epb4, Epb4.1l1
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_HUMAN
NC score	0.618461 (rank : 67)	θ value	1.6774e-38 (rank : 26)
Query Neighborhood Hits	155	Target Neighborhood Hits	157	Shared Neighborhood Hits	50
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

E41L1_HUMAN
NC score	0.615658 (rank : 68)	θ value	6.37413e-38 (rank : 29)
Query Neighborhood Hits	155	Target Neighborhood Hits	180	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H4G0, O15046, Q4VXN4	Gene names	EPB41L1, KIAA0338
Domain Architecture
Description	Band 4.1-like protein 1 (Neuronal protein 4.1) (4.1N).

41_MOUSE
NC score	0.615193 (rank : 69)	θ value	1.85459e-37 (rank : 32)
Query Neighborhood Hits	155	Target Neighborhood Hits	184	Shared Neighborhood Hits	52
SwissProt Accessions	P48193, Q68FF1, Q6NVF5	Gene names	Epb41, Epb4.1
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (4.1R).

E41L3_MOUSE
NC score	0.612034 (rank : 70)	θ value	3.99248e-40 (rank : 17)
Query Neighborhood Hits	155	Target Neighborhood Hits	250	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

E41L2_HUMAN
NC score	0.610349 (rank : 71)	θ value	1.98146e-39 (rank : 18)
Query Neighborhood Hits	155	Target Neighborhood Hits	287	Shared Neighborhood Hits	51
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

E41L2_MOUSE
NC score	0.595191 (rank : 72)	θ value	1.98146e-39 (rank : 19)
Query Neighborhood Hits	155	Target Neighborhood Hits	459	Shared Neighborhood Hits	51
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MYLIP_MOUSE
NC score	0.586197 (rank : 73)	θ value	1.86321e-21 (rank : 92)
Query Neighborhood Hits	155	Target Neighborhood Hits	139	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BM54, Q3TX01, Q8BLY9, Q91Z47	Gene names	Mylip
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

MYLIP_HUMAN
NC score	0.571550 (rank : 74)	θ value	1.33526e-19 (rank : 93)
Query Neighborhood Hits	155	Target Neighborhood Hits	162	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WY64, Q9BU73, Q9NRL9, Q9UHE7	Gene names	MYLIP, BZF1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase MYLIP (EC 6.3.2.-) (Myosin regulatory light chain- interacting protein) (MIR).

PTPRS_HUMAN
NC score	0.567690 (rank : 75)	θ value	2.50074e-42 (rank : 12)
Query Neighborhood Hits	155	Target Neighborhood Hits	472	Shared Neighborhood Hits	67
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

FRM4B_MOUSE
NC score	0.565420 (rank : 76)	θ value	1.99067e-23 (rank : 88)
Query Neighborhood Hits	155	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q920B0, Q3V1S1, Q9ESP9	Gene names	Frmd4b
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1) (Golgi- associated band 4.1-like protein) (GOBLIN).

FRM4B_HUMAN
NC score	0.564452 (rank : 77)	θ value	2.20094e-22 (rank : 89)
Query Neighborhood Hits	155	Target Neighborhood Hits	117	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y2L6, Q8TAI3	Gene names	FRMD4B, KIAA1013
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4B (GRP1-binding protein GRSP1).

PTPRD_HUMAN
NC score	0.557376 (rank : 78)	θ value	5.03882e-43 (rank : 11)
Query Neighborhood Hits	155	Target Neighborhood Hits	485	Shared Neighborhood Hits	68
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

FRM4A_HUMAN
NC score	0.556769 (rank : 79)	θ value	1.09232e-21 (rank : 91)
Query Neighborhood Hits	155	Target Neighborhood Hits	110	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P2Q2	Gene names	FRMD4A, FRMD4, KIAA1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

FRM4A_MOUSE
NC score	0.555796 (rank : 80)	θ value	6.40375e-22 (rank : 90)
Query Neighborhood Hits	155	Target Neighborhood Hits	108	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BIE6, Q6PDJ4, Q8CHA6	Gene names	Frmd4a, Frmd4, Kiaa1294
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 4A.

PTPRF_HUMAN
NC score	0.553403 (rank : 81)	θ value	1.98146e-39 (rank : 21)
Query Neighborhood Hits	155	Target Neighborhood Hits	489	Shared Neighborhood Hits	67
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRD_MOUSE
NC score	0.547993 (rank : 82)	θ value	1.79215e-40 (rank : 16)
Query Neighborhood Hits	155	Target Neighborhood Hits	491	Shared Neighborhood Hits	68
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

MERL_MOUSE
NC score	0.539669 (rank : 83)	θ value	8.63488e-27 (rank : 87)
Query Neighborhood Hits	155	Target Neighborhood Hits	524	Shared Neighborhood Hits	56
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.539243 (rank : 84)	θ value	6.61148e-27 (rank : 84)
Query Neighborhood Hits	155	Target Neighborhood Hits	532	Shared Neighborhood Hits	56
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

FARP1_HUMAN
NC score	0.515959 (rank : 85)	θ value	1.37539e-32 (rank : 60)
Query Neighborhood Hits	155	Target Neighborhood Hits	241	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

EZRI_HUMAN
NC score	0.509815 (rank : 86)	θ value	2.27234e-27 (rank : 80)
Query Neighborhood Hits	155	Target Neighborhood Hits	663	Shared Neighborhood Hits	53
SwissProt Accessions	P15311, P23714, Q96CU8, Q9NSJ4	Gene names	VIL2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

EZRI_MOUSE
NC score	0.506409 (rank : 87)	θ value	3.87602e-27 (rank : 82)
Query Neighborhood Hits	155	Target Neighborhood Hits	693	Shared Neighborhood Hits	55
SwissProt Accessions	P26040, Q80ZT8, Q9DCI1	Gene names	Vil2
Domain Architecture
Description	Ezrin (p81) (Cytovillin) (Villin-2).

FRMD6_MOUSE
NC score	0.501040 (rank : 88)	θ value	2.28291e-11 (rank : 94)
Query Neighborhood Hits	155	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C0V9, Q8BW34	Gene names	Frmd6
Domain Architecture
Description	FERM domain-containing protein 6.

FARP2_HUMAN
NC score	0.499246 (rank : 89)	θ value	1.85889e-29 (rank : 72)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	46
SwissProt Accessions	O94887, Q53QM5, Q8WU27, Q9UFE7	Gene names	FARP2, KIAA0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

RADI_HUMAN
NC score	0.497901 (rank : 90)	θ value	6.61148e-27 (rank : 85)
Query Neighborhood Hits	155	Target Neighborhood Hits	741	Shared Neighborhood Hits	55
SwissProt Accessions	P35241, Q86Y61	Gene names	RDX
Domain Architecture
Description	Radixin.

FARP2_MOUSE
NC score	0.495403 (rank : 91)	θ value	8.3442e-30 (rank : 71)
Query Neighborhood Hits	155	Target Neighborhood Hits	209	Shared Neighborhood Hits	46
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

RADI_MOUSE
NC score	0.495123 (rank : 92)	θ value	6.61148e-27 (rank : 86)
Query Neighborhood Hits	155	Target Neighborhood Hits	773	Shared Neighborhood Hits	54
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

FRMD6_HUMAN
NC score	0.493628 (rank : 93)	θ value	1.25267e-09 (rank : 95)
Query Neighborhood Hits	155	Target Neighborhood Hits	60	Shared Neighborhood Hits	43
SwissProt Accessions	Q96NE9, Q5HYF2, Q8N2X1, Q8WUH7	Gene names	FRMD6, C14orf31
Domain Architecture
Description	FERM domain-containing protein 6 (Willin).

FRMD1_HUMAN
NC score	0.490472 (rank : 94)	θ value	6.21693e-09 (rank : 96)
Query Neighborhood Hits	155	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N878, Q5SZU7, Q9UFB0	Gene names	FRMD1
Domain Architecture	No domain graphic available
Description	FERM domain-containing protein 1.

MOES_HUMAN
NC score	0.467719 (rank : 95)	θ value	2.05525e-28 (rank : 73)
Query Neighborhood Hits	155	Target Neighborhood Hits	892	Shared Neighborhood Hits	55
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MOES_MOUSE
NC score	0.462354 (rank : 96)	θ value	3.50572e-28 (rank : 75)
Query Neighborhood Hits	155	Target Neighborhood Hits	923	Shared Neighborhood Hits	56
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

TLN1_HUMAN
NC score	0.261582 (rank : 97)	θ value	0.000270298 (rank : 97)
Query Neighborhood Hits	155	Target Neighborhood Hits	218	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y490, Q86YD0, Q9NZQ2, Q9UHH8, Q9UPX3	Gene names	TLN1, KIAA1027, TLN
Domain Architecture
Description	Talin-1.

TLN1_MOUSE
NC score	0.259267 (rank : 98)	θ value	0.000270298 (rank : 98)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	47
SwissProt Accessions	P26039, Q8VEF0	Gene names	Tln1, Tln
Domain Architecture
Description	Talin-1.

TLN2_MOUSE
NC score	0.254122 (rank : 99)	θ value	0.0148317 (rank : 101)
Query Neighborhood Hits	155	Target Neighborhood Hits	149	Shared Neighborhood Hits	53
SwissProt Accessions	Q71LX4, Q8BWK0	Gene names	Tln2
Domain Architecture	No domain graphic available
Description	Talin-2.

TLN2_HUMAN
NC score	0.250047 (rank : 100)	θ value	0.00869519 (rank : 100)
Query Neighborhood Hits	155	Target Neighborhood Hits	157	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y4G6	Gene names	TLN2, KIAA0320
Domain Architecture
Description	Talin-2.

DUS23_MOUSE
NC score	0.218523 (rank : 101)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	155	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

DUS23_HUMAN
NC score	0.209048 (rank : 102)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	155	Target Neighborhood Hits	98	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

FINC_HUMAN
NC score	0.111445 (rank : 103)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	155	Target Neighborhood Hits	302	Shared Neighborhood Hits	22
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
NC score	0.110631 (rank : 104)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	155	Target Neighborhood Hits	309	Shared Neighborhood Hits	22
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

CC14B_HUMAN
NC score	0.106097 (rank : 105)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	155	Target Neighborhood Hits	114	Shared Neighborhood Hits	53
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CC14B_MOUSE
NC score	0.103394 (rank : 106)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	155	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

FNDC3_HUMAN
NC score	0.100963 (rank : 107)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
NC score	0.094676 (rank : 108)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	155	Target Neighborhood Hits	207	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

CC14A_MOUSE
NC score	0.094506 (rank : 109)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	155	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_HUMAN
NC score	0.091721 (rank : 110)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	155	Target Neighborhood Hits	133	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

TP4A1_HUMAN
NC score	0.086393 (rank : 111)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	155	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.086393 (rank : 112)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	155	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

DCC_HUMAN
NC score	0.083878 (rank : 113)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	155	Target Neighborhood Hits	583	Shared Neighborhood Hits	26
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

PTEN_HUMAN
NC score	0.082935 (rank : 114)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	155	Target Neighborhood Hits	72	Shared Neighborhood Hits	30
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.082934 (rank : 115)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	155	Target Neighborhood Hits	73	Shared Neighborhood Hits	30
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

NEO1_MOUSE
NC score	0.081876 (rank : 116)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	155	Target Neighborhood Hits	523	Shared Neighborhood Hits	25
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

DCC_MOUSE
NC score	0.081026 (rank : 117)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	155	Target Neighborhood Hits	896	Shared Neighborhood Hits	29
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

NEO1_HUMAN
NC score	0.079534 (rank : 118)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	155	Target Neighborhood Hits	530	Shared Neighborhood Hits	25
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

TENN_MOUSE
NC score	0.077158 (rank : 119)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	155	Target Neighborhood Hits	484	Shared Neighborhood Hits	20
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

COCA1_MOUSE
NC score	0.073990 (rank : 120)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	155	Target Neighborhood Hits	467	Shared Neighborhood Hits	23
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_HUMAN
NC score	0.072556 (rank : 121)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	155	Target Neighborhood Hits	458	Shared Neighborhood Hits	27
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MAMC2_MOUSE
NC score	0.072386 (rank : 122)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	155	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

SDK2_MOUSE
NC score	0.071435 (rank : 123)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	155	Target Neighborhood Hits	480	Shared Neighborhood Hits	21
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

TP4A2_HUMAN
NC score	0.070266 (rank : 124)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	155	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.070266 (rank : 125)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	155	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

CA106_HUMAN
NC score	0.070092 (rank : 126)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	155	Target Neighborhood Hits	124	Shared Neighborhood Hits	7
SwissProt Accessions	Q3KP66, Q9NV65, Q9NVI0	Gene names	C1orf106
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106.

USH2A_HUMAN
NC score	0.069591 (rank : 127)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	155	Target Neighborhood Hits	600	Shared Neighborhood Hits	28
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

MAMC2_HUMAN
NC score	0.069437 (rank : 128)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	155	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

SDK1_MOUSE
NC score	0.069038 (rank : 129)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	155	Target Neighborhood Hits	495	Shared Neighborhood Hits	24
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

CA106_MOUSE
NC score	0.068986 (rank : 130)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	155	Target Neighborhood Hits	89	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN12, Q7TN27, Q8BGK3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf106 homolog.

SDK2_HUMAN
NC score	0.068719 (rank : 131)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	155	Target Neighborhood Hits	495	Shared Neighborhood Hits	21
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_HUMAN
NC score	0.067878 (rank : 132)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	155	Target Neighborhood Hits	511	Shared Neighborhood Hits	23
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

TP4A3_HUMAN
NC score	0.067025 (rank : 133)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	155	Target Neighborhood Hits	62	Shared Neighborhood Hits	26
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

USH2A_MOUSE
NC score	0.066515 (rank : 134)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	155	Target Neighborhood Hits	626	Shared Neighborhood Hits	24
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

TENN_HUMAN
NC score	0.066205 (rank : 135)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	155	Target Neighborhood Hits	453	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_MOUSE
NC score	0.065444 (rank : 136)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	155	Target Neighborhood Hits	531	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENR_HUMAN
NC score	0.065138 (rank : 137)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	155	Target Neighborhood Hits	526	Shared Neighborhood Hits	19
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ITB4_HUMAN
NC score	0.064667 (rank : 138)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	155	Target Neighborhood Hits	458	Shared Neighborhood Hits	19
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

L1CAM_MOUSE
NC score	0.062854 (rank : 139)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	155	Target Neighborhood Hits	457	Shared Neighborhood Hits	23
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

L1CAM_HUMAN
NC score	0.062073 (rank : 140)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	155	Target Neighborhood Hits	457	Shared Neighborhood Hits	18
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

DSCAM_HUMAN
NC score	0.062035 (rank : 141)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	155	Target Neighborhood Hits	524	Shared Neighborhood Hits	20
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

DSCL1_HUMAN
NC score	0.062035 (rank : 142)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	155	Target Neighborhood Hits	589	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

NRCAM_MOUSE
NC score	0.061890 (rank : 143)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	155	Target Neighborhood Hits	432	Shared Neighborhood Hits	18
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

CDKN3_HUMAN
NC score	0.061618 (rank : 144)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	155	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

COEA1_MOUSE
NC score	0.061140 (rank : 145)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	155	Target Neighborhood Hits	402	Shared Neighborhood Hits	20
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

NRCAM_HUMAN
NC score	0.059932 (rank : 146)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	155	Target Neighborhood Hits	439	Shared Neighborhood Hits	16
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

CNTN5_HUMAN
NC score	0.059756 (rank : 147)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	155	Target Neighborhood Hits	446	Shared Neighborhood Hits	19
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

TP4A3_MOUSE
NC score	0.059660 (rank : 148)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	155	Target Neighborhood Hits	60	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

KRIT1_HUMAN
NC score	0.059440 (rank : 149)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	155	Target Neighborhood Hits	258	Shared Neighborhood Hits	23
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

KRIT1_MOUSE
NC score	0.059070 (rank : 150)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	155	Target Neighborhood Hits	258	Shared Neighborhood Hits	25
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

CNTN5_MOUSE
NC score	0.058399 (rank : 151)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	155	Target Neighborhood Hits	434	Shared Neighborhood Hits	17
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CNTN2_HUMAN
NC score	0.058065 (rank : 152)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	155	Target Neighborhood Hits	440	Shared Neighborhood Hits	16
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

MDGA1_HUMAN
NC score	0.058052 (rank : 153)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	155	Target Neighborhood Hits	358	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

CNTN2_MOUSE
NC score	0.057935 (rank : 154)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	155	Target Neighborhood Hits	450	Shared Neighborhood Hits	16
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CO7A1_HUMAN
NC score	0.057537 (rank : 155)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	155	Target Neighborhood Hits	807	Shared Neighborhood Hits	22
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

TARSH_HUMAN
NC score	0.057079 (rank : 156)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	155	Target Neighborhood Hits	768	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MYOM1_MOUSE
NC score	0.057073 (rank : 157)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	155	Target Neighborhood Hits	415	Shared Neighborhood Hits	18
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

RES18_MOUSE
NC score	0.056520 (rank : 158)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	155	Target Neighborhood Hits	4	Shared Neighborhood Hits	2
SwissProt Accessions	P47939	Gene names	Resp18
Domain Architecture	No domain graphic available
Description	Regulated endocrine-specific protein 18 precursor [Contains: Regulated endocrine-specific protein 18; Triskadecapeptide].

MAMC1_MOUSE
NC score	0.056113 (rank : 159)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

CNTN1_MOUSE
NC score	0.055164 (rank : 160)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	155	Target Neighborhood Hits	422	Shared Neighborhood Hits	15
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

MAMC1_HUMAN
NC score	0.055128 (rank : 161)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

TENA_HUMAN
NC score	0.054940 (rank : 162)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	155	Target Neighborhood Hits	631	Shared Neighborhood Hits	22
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

COEA1_HUMAN
NC score	0.054479 (rank : 163)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	155	Target Neighborhood Hits	427	Shared Neighborhood Hits	19
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

NFASC_HUMAN
NC score	0.054412 (rank : 164)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	155	Target Neighborhood Hits	497	Shared Neighborhood Hits	17
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

CNTN1_HUMAN
NC score	0.054039 (rank : 165)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	155	Target Neighborhood Hits	431	Shared Neighborhood Hits	15
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

MYOM1_HUMAN
NC score	0.053720 (rank : 166)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	155	Target Neighborhood Hits	405	Shared Neighborhood Hits	15
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

CNTN3_MOUSE
NC score	0.053194 (rank : 167)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	155	Target Neighborhood Hits	447	Shared Neighborhood Hits	19
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN6_HUMAN
NC score	0.052460 (rank : 168)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	155	Target Neighborhood Hits	422	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

PUNC_HUMAN
NC score	0.052323 (rank : 169)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	155	Target Neighborhood Hits	449	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

NFASC_MOUSE
NC score	0.052172 (rank : 170)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	155	Target Neighborhood Hits	475	Shared Neighborhood Hits	17
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

ROBO3_MOUSE
NC score	0.051719 (rank : 171)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	155	Target Neighborhood Hits	524	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

LIFR_MOUSE
NC score	0.051192 (rank : 172)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	155	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

CNTN3_HUMAN
NC score	0.051024 (rank : 173)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	155	Target Neighborhood Hits	455	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

MYOM2_HUMAN
NC score	0.050279 (rank : 174)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	155	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

TENA_MOUSE
NC score	0.050101 (rank : 175)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	155	Target Neighborhood Hits	596	Shared Neighborhood Hits	19
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

MYO7A_MOUSE
NC score	0.038889 (rank : 176)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	155	Target Neighborhood Hits	235	Shared Neighborhood Hits	28
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_HUMAN
NC score	0.038672 (rank : 177)	θ value	1.06291 (rank : 113)
Query Neighborhood Hits	155	Target Neighborhood Hits	209	Shared Neighborhood Hits	30
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

TITIN_HUMAN
NC score	0.035852 (rank : 178)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	155	Target Neighborhood Hits	2923	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MYPN_HUMAN
NC score	0.031383 (rank : 179)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	155	Target Neighborhood Hits	418	Shared Neighborhood Hits	11
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

FRAT1_HUMAN
NC score	0.027989 (rank : 180)	θ value	0.21417 (rank : 104)
Query Neighborhood Hits	155	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q92837, Q8NE74, Q8TDW9	Gene names	FRAT1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

MYO10_HUMAN
NC score	0.022772 (rank : 181)	θ value	0.0961366 (rank : 103)
Query Neighborhood Hits	155	Target Neighborhood Hits	920	Shared Neighborhood Hits	29
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

AFAD_HUMAN
NC score	0.022442 (rank : 182)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	155	Target Neighborhood Hits	689	Shared Neighborhood Hits	15
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

K1024_HUMAN
NC score	0.022189 (rank : 183)	θ value	0.0431538 (rank : 102)
Query Neighborhood Hits	155	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPX6	Gene names	KIAA1024
Domain Architecture
Description	UPF0258 protein KIAA1024.

L2GL1_MOUSE
NC score	0.021273 (rank : 184)	θ value	0.00390308 (rank : 99)
Query Neighborhood Hits	155	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q80Y17, Q61856, Q7TNV3, Q8BN92	Gene names	Llgl1, Llglh
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Mlgl) (Mgl-1).

SETX_HUMAN
NC score	0.019384 (rank : 185)	θ value	0.47712 (rank : 108)
Query Neighborhood Hits	155	Target Neighborhood Hits	368	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

MLL3_MOUSE
NC score	0.017958 (rank : 186)	θ value	0.365318 (rank : 107)
Query Neighborhood Hits	155	Target Neighborhood Hits	1399	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CN037_HUMAN
NC score	0.017630 (rank : 187)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	155	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q86TY3, Q6P5Q1, Q86TY1	Gene names	C14orf37
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 precursor.

US6NL_MOUSE
NC score	0.016858 (rank : 188)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	155	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

AP2B_HUMAN
NC score	0.016351 (rank : 189)	θ value	0.365318 (rank : 105)
Query Neighborhood Hits	155	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q92481, Q5JYX6, Q9NQ63, Q9NU99, Q9UJI7, Q9Y214, Q9Y3K3	Gene names	TFAP2B
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

AP2B_MOUSE
NC score	0.016334 (rank : 190)	θ value	0.365318 (rank : 106)
Query Neighborhood Hits	155	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q61313	Gene names	Tfap2b, Tcfap2b
Domain Architecture
Description	Transcription factor AP-2 beta (AP2-beta) (Activating enhancer-binding protein 2 beta).

TP53B_HUMAN
NC score	0.015437 (rank : 191)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	155	Target Neighborhood Hits	413	Shared Neighborhood Hits	16
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

LIPA1_HUMAN
NC score	0.013604 (rank : 192)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	155	Target Neighborhood Hits	1294	Shared Neighborhood Hits	21
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

SMAD2_MOUSE
NC score	0.011371 (rank : 193)	θ value	0.813845 (rank : 111)
Query Neighborhood Hits	155	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q62432, Q9D8P6	Gene names	Smad2, Madh2, Madr2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2).

SMAD2_HUMAN
NC score	0.011370 (rank : 194)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	155	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q15796	Gene names	SMAD2, MADH2, MADR2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (hMAD-2) (JV18-1) (hSMAD2).

AKAP6_HUMAN
NC score	0.010430 (rank : 195)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	155	Target Neighborhood Hits	263	Shared Neighborhood Hits	9
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

AAT1_HUMAN
NC score	0.010284 (rank : 196)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z4T9, Q68DX2, Q8TD41, Q96A45, Q96JE8	Gene names	AAT1, C3orf15
Domain Architecture	No domain graphic available
Description	AMY-1-associating protein expressed in testis 1 (AAT-1).

AKAP2_MOUSE
NC score	0.010100 (rank : 197)	θ value	1.81305 (rank : 116)
Query Neighborhood Hits	155	Target Neighborhood Hits	385	Shared Neighborhood Hits	9
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

TCF7_HUMAN
NC score	0.009373 (rank : 198)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	155	Target Neighborhood Hits	186	Shared Neighborhood Hits	4
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

SMAD3_HUMAN
NC score	0.008597 (rank : 199)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	155	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	P84022, O09064, O09144, O14510, O35273, Q92940, Q93002, Q9GKR4	Gene names	SMAD3, MADH3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (hMAD-3) (JV15-2) (hSMAD3).

SMAD3_MOUSE
NC score	0.008597 (rank : 200)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	155	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BUN5, O09064, O09144, O14510, O35273, Q8BX84, Q92940, Q93002, Q9GKR4	Gene names	Smad3, Madh3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (mMad3).

ANR26_MOUSE
NC score	0.007492 (rank : 201)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	155	Target Neighborhood Hits	1554	Shared Neighborhood Hits	22
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NU205_HUMAN
NC score	0.006934 (rank : 202)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	155	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q92621, Q86YC1	Gene names	NUP205, C7orf14, KIAA0225
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup205 (Nucleoporin Nup205) (205 kDa nucleoporin).

EP300_HUMAN
NC score	0.006884 (rank : 203)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	155	Target Neighborhood Hits	821	Shared Neighborhood Hits	12
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FA5_HUMAN
NC score	0.006278 (rank : 204)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	155	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

MLH1_HUMAN
NC score	0.006118 (rank : 205)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	155	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P40692	Gene names	MLH1, COCA2
Domain Architecture
Description	DNA mismatch repair protein Mlh1 (MutL protein homolog 1).

SSH2_HUMAN
NC score	0.005979 (rank : 206)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	155	Target Neighborhood Hits	140	Shared Neighborhood Hits	6
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

ARI1A_HUMAN
NC score	0.005627 (rank : 207)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	155	Target Neighborhood Hits	787	Shared Neighborhood Hits	15
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

RIF1_HUMAN
NC score	0.005376 (rank : 208)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	155	Target Neighborhood Hits	320	Shared Neighborhood Hits	7
SwissProt Accessions	Q5UIP0, Q5H9R3, Q5UIP2, Q66YK6, Q6PRU2, Q8TE94, Q99772, Q9H830, Q9H9B9, Q9NVP5, Q9Y4R4	Gene names	RIF1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog).

IMPG1_MOUSE
NC score	0.005135 (rank : 209)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	155	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

PAPPA_MOUSE
NC score	0.004708 (rank : 210)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	155	Target Neighborhood Hits	153	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

DMRT1_MOUSE
NC score	0.004242 (rank : 211)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	155	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ59, Q9QZ37, Q9QZA4	Gene names	Dmrt1
Domain Architecture
Description	Doublesex- and mab-3-related transcription factor 1.

SSH2_MOUSE
NC score	0.003529 (rank : 212)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	155	Target Neighborhood Hits	119	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

RIN2_HUMAN
NC score	0.003194 (rank : 213)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	155	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WYP3, Q00425, Q5TFT8, Q9BQL3, Q9H071	Gene names	RIN2, RASSF4
Domain Architecture
Description	Ras and Rab interactor 2 (Ras interaction/interference protein 2) (Ras inhibitor JC265) (Ras association domain family 4).

BRCA1_MOUSE
NC score	0.002414 (rank : 214)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	155	Target Neighborhood Hits	436	Shared Neighborhood Hits	10
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

PARVA_HUMAN
NC score	0.001888 (rank : 215)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	155	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NVD7, Q96C85, Q9HA48	Gene names	PARVA
Domain Architecture
Description	Alpha-parvin (Calponin-like integrin-linked kinase-binding protein) (CH-ILKBP).

K0494_HUMAN
NC score	0.001828 (rank : 216)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	155	Target Neighborhood Hits	230	Shared Neighborhood Hits	4
SwissProt Accessions	O75071	Gene names	KIAA0494
Domain Architecture	No domain graphic available
Description	Uncharacterized calcium-binding protein KIAA0494.

ACES_MOUSE
NC score	0.000899 (rank : 217)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	155	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

COIA1_HUMAN
NC score	-0.000150 (rank : 218)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	155	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

STF1_HUMAN
NC score	-0.001798 (rank : 219)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	155	Target Neighborhood Hits	132	Shared Neighborhood Hits	2
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

REM1_MOUSE
NC score	-0.003511 (rank : 220)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	2
SwissProt Accessions	O35929	Gene names	Rem1, Rem
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1).

PRP4B_HUMAN
NC score	-0.005745 (rank : 221)	θ value	3.0926 (rank : 124)
Query Neighborhood Hits	155	Target Neighborhood Hits	1030	Shared Neighborhood Hits	10
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

PRP4B_MOUSE
NC score	-0.006400 (rank : 222)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	155	Target Neighborhood Hits	1040	Shared Neighborhood Hits	9
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

CD2L6_HUMAN
NC score	-0.007173 (rank : 223)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	155	Target Neighborhood Hits	844	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWU1, Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2	Gene names	CDC2L6, CDK11, KIAA1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11).

CD2L6_MOUSE
NC score	-0.007183 (rank : 224)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	155	Target Neighborhood Hits	851	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BWD8, Q80TM1	Gene names	Cdc2l6, Kiaa1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6).

MYNN_HUMAN
NC score	-0.008982 (rank : 225)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	155	Target Neighborhood Hits	826	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPC7, Q6QHA6, Q6QHA7, Q6R3G1, Q6R3G2, Q6R4A0, Q7Z716, Q7Z717, Q86Z11, Q86Z12, Q9NS01, Q9UIW8	Gene names	MYNN, OSZF, ZBTB31
Domain Architecture	No domain graphic available
Description	Myoneurin (Zinc finger and BTB domain-containing protein 31).