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Network neighborhood for query Sequence : IMPG1_MOUSE

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IMPG1_MOUSE
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IMPG1_HUMAN
θ value	0 (rank : 1)	NC score	0.961032 (rank : 2)
Query Neighborhood Hits	50	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

IMPG1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	50	Target Neighborhood Hits	50	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

MUC1_MOUSE
θ value	0.000602161 (rank : 3)	NC score	0.148926 (rank : 3)
Query Neighborhood Hits	50	Target Neighborhood Hits	388	Shared Neighborhood Hits	10
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

IWS1_HUMAN
θ value	0.00869519 (rank : 4)	NC score	0.063459 (rank : 8)
Query Neighborhood Hits	50	Target Neighborhood Hits	1241	Shared Neighborhood Hits	11
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

UROL1_HUMAN
θ value	0.0113563 (rank : 5)	NC score	0.092515 (rank : 4)
Query Neighborhood Hits	50	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

GP110_HUMAN
θ value	0.0148317 (rank : 6)	NC score	0.080311 (rank : 6)
Query Neighborhood Hits	50	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

IWS1_MOUSE
θ value	0.0193708 (rank : 7)	NC score	0.062257 (rank : 9)
Query Neighborhood Hits	50	Target Neighborhood Hits	1258	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MUC1_HUMAN
θ value	0.0330416 (rank : 8)	NC score	0.059147 (rank : 10)
Query Neighborhood Hits	50	Target Neighborhood Hits	975	Shared Neighborhood Hits	14
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

GP116_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.064001 (rank : 7)
Query Neighborhood Hits	50	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

HDC_HUMAN
θ value	0.21417 (rank : 10)	NC score	0.085924 (rank : 5)
Query Neighborhood Hits	50	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBI9	Gene names	HECA, HDC
Domain Architecture	No domain graphic available
Description	Headcase protein homolog (hHDC).

CRUM1_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.031892 (rank : 17)
Query Neighborhood Hits	50	Target Neighborhood Hits	444	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

ZAN_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.043952 (rank : 11)
Query Neighborhood Hits	50	Target Neighborhood Hits	808	Shared Neighborhood Hits	17
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

EGF_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.038299 (rank : 13)
Query Neighborhood Hits	50	Target Neighborhood Hits	358	Shared Neighborhood Hits	15
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

CELR3_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.020468 (rank : 25)
Query Neighborhood Hits	50	Target Neighborhood Hits	687	Shared Neighborhood Hits	15
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

DMXL1_MOUSE
θ value	1.06291 (rank : 15)	NC score	0.025310 (rank : 21)
Query Neighborhood Hits	50	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

EGF_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.041766 (rank : 12)
Query Neighborhood Hits	50	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

RAI1_HUMAN
θ value	1.06291 (rank : 17)	NC score	0.031106 (rank : 18)
Query Neighborhood Hits	50	Target Neighborhood Hits	360	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CPXM2_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.016596 (rank : 32)
Query Neighborhood Hits	50	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

MATN2_MOUSE
θ value	1.38821 (rank : 19)	NC score	0.022816 (rank : 23)
Query Neighborhood Hits	50	Target Neighborhood Hits	356	Shared Neighborhood Hits	12
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

ZN687_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.011900 (rank : 40)
Query Neighborhood Hits	50	Target Neighborhood Hits	913	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

MDC1_MOUSE
θ value	1.81305 (rank : 21)	NC score	0.037506 (rank : 14)
Query Neighborhood Hits	50	Target Neighborhood Hits	998	Shared Neighborhood Hits	16
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

XPP2_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.033478 (rank : 16)
Query Neighborhood Hits	50	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	O43895, O75994	Gene names	XPNPEP2
Domain Architecture
Description	Xaa-Pro aminopeptidase 2 precursor (EC 3.4.11.9) (X-Pro aminopeptidase 2) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane- bound AmP) (mAmP) (Aminoacylproline aminopeptidase).

ATBF1_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.018494 (rank : 31)
Query Neighborhood Hits	50	Target Neighborhood Hits	1841	Shared Neighborhood Hits	16
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

AT11A_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.010593 (rank : 43)
Query Neighborhood Hits	50	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P98197	Gene names	Atp11a
Domain Architecture
Description	Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase class I type 11A) (ATPase IS).

EPIPL_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.019096 (rank : 28)
Query Neighborhood Hits	50	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	P58107, Q76E58	Gene names	EPPK1, EPIPL
Domain Architecture
Description	Epiplakin (450 kDa epidermal antigen).

NOTC2_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.019946 (rank : 27)
Query Neighborhood Hits	50	Target Neighborhood Hits	1113	Shared Neighborhood Hits	21
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_MOUSE
θ value	3.0926 (rank : 27)	NC score	0.024040 (rank : 22)
Query Neighborhood Hits	50	Target Neighborhood Hits	872	Shared Neighborhood Hits	15
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

POLS_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.030441 (rank : 19)
Query Neighborhood Hits	50	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XG87, O43289, Q9Y6C1	Gene names	POLS, TRF4
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7) (Topoisomerase-related function protein 4-1) (TRF4-1) (LAK-1) (DNA polymerase kappa).

DDX55_HUMAN
θ value	4.03905 (rank : 29)	NC score	0.012188 (rank : 38)
Query Neighborhood Hits	50	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.012204 (rank : 37)
Query Neighborhood Hits	50	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

ENTK_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.015905 (rank : 33)
Query Neighborhood Hits	50	Target Neighborhood Hits	310	Shared Neighborhood Hits	6
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ZAN_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.036064 (rank : 15)
Query Neighborhood Hits	50	Target Neighborhood Hits	679	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

AFF4_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.020116 (rank : 26)
Query Neighborhood Hits	50	Target Neighborhood Hits	581	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ATBF1_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.014658 (rank : 34)
Query Neighborhood Hits	50	Target Neighborhood Hits	1547	Shared Neighborhood Hits	11
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

POLS_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.027742 (rank : 20)
Query Neighborhood Hits	50	Target Neighborhood Hits	91	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PB75	Gene names	Pols
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7).

ANR38_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.011959 (rank : 39)
Query Neighborhood Hits	50	Target Neighborhood Hits	512	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

DOCK3_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.009988 (rank : 44)
Query Neighborhood Hits	50	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

FAT2_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.011027 (rank : 42)
Query Neighborhood Hits	50	Target Neighborhood Hits	507	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

NCOR2_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.022644 (rank : 24)
Query Neighborhood Hits	50	Target Neighborhood Hits	790	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

PTN21_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.005135 (rank : 49)
Query Neighborhood Hits	50	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

SL9A3_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.011750 (rank : 41)
Query Neighborhood Hits	50	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	P48764	Gene names	SLC9A3, NHE3
Domain Architecture
Description	Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3).

VASP_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.018812 (rank : 29)
Query Neighborhood Hits	50	Target Neighborhood Hits	195	Shared Neighborhood Hits	5
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

VITRN_MOUSE
θ value	6.88961 (rank : 43)	NC score	0.012776 (rank : 35)
Query Neighborhood Hits	50	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

BPTF_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.012301 (rank : 36)
Query Neighborhood Hits	50	Target Neighborhood Hits	786	Shared Neighborhood Hits	8
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CDX2_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.005160 (rank : 48)
Query Neighborhood Hits	50	Target Neighborhood Hits	336	Shared Neighborhood Hits	5
SwissProt Accessions	P43241	Gene names	Cdx2, Cdx-2
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2).

EZH1_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.009741 (rank : 45)
Query Neighborhood Hits	50	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

GAK6_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.005181 (rank : 47)
Query Neighborhood Hits	50	Target Neighborhood Hits	392	Shared Neighborhood Hits	5
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

LRP1_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.018572 (rank : 30)
Query Neighborhood Hits	50	Target Neighborhood Hits	617	Shared Neighborhood Hits	14
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

PHLPP_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.008721 (rank : 46)
Query Neighborhood Hits	50	Target Neighborhood Hits	604	Shared Neighborhood Hits	8
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

ZNF32_HUMAN
θ value	8.99809 (rank : 50)	NC score	-0.000068 (rank : 50)
Query Neighborhood Hits	50	Target Neighborhood Hits	735	Shared Neighborhood Hits	5
SwissProt Accessions	P17041, Q92951	Gene names	ZNF32, KOX30
Domain Architecture	No domain graphic available
Description	Zinc finger protein 32 (Zinc finger protein KOX30) (C2H2-546).

Hits sorted by NC score

IMPG1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	50	Target Neighborhood Hits	50	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

IMPG1_HUMAN
NC score	0.961032 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	50	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

MUC1_MOUSE
NC score	0.148926 (rank : 3)	θ value	0.000602161 (rank : 3)
Query Neighborhood Hits	50	Target Neighborhood Hits	388	Shared Neighborhood Hits	10
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

UROL1_HUMAN
NC score	0.092515 (rank : 4)	θ value	0.0113563 (rank : 5)
Query Neighborhood Hits	50	Target Neighborhood Hits	213	Shared Neighborhood Hits	10
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

HDC_HUMAN
NC score	0.085924 (rank : 5)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	50	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBI9	Gene names	HECA, HDC
Domain Architecture	No domain graphic available
Description	Headcase protein homolog (hHDC).

GP110_HUMAN
NC score	0.080311 (rank : 6)	θ value	0.0148317 (rank : 6)
Query Neighborhood Hits	50	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP116_HUMAN
NC score	0.064001 (rank : 7)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	50	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

IWS1_HUMAN
NC score	0.063459 (rank : 8)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	50	Target Neighborhood Hits	1241	Shared Neighborhood Hits	11
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
NC score	0.062257 (rank : 9)	θ value	0.0193708 (rank : 7)
Query Neighborhood Hits	50	Target Neighborhood Hits	1258	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MUC1_HUMAN
NC score	0.059147 (rank : 10)	θ value	0.0330416 (rank : 8)
Query Neighborhood Hits	50	Target Neighborhood Hits	975	Shared Neighborhood Hits	14
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

ZAN_MOUSE
NC score	0.043952 (rank : 11)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	50	Target Neighborhood Hits	808	Shared Neighborhood Hits	17
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

EGF_HUMAN
NC score	0.041766 (rank : 12)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	50	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
NC score	0.038299 (rank : 13)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	50	Target Neighborhood Hits	358	Shared Neighborhood Hits	15
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

MDC1_MOUSE
NC score	0.037506 (rank : 14)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	50	Target Neighborhood Hits	998	Shared Neighborhood Hits	16
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ZAN_HUMAN
NC score	0.036064 (rank : 15)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	50	Target Neighborhood Hits	679	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

XPP2_HUMAN
NC score	0.033478 (rank : 16)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	50	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	O43895, O75994	Gene names	XPNPEP2
Domain Architecture
Description	Xaa-Pro aminopeptidase 2 precursor (EC 3.4.11.9) (X-Pro aminopeptidase 2) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane- bound AmP) (mAmP) (Aminoacylproline aminopeptidase).

CRUM1_MOUSE
NC score	0.031892 (rank : 17)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	50	Target Neighborhood Hits	444	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

RAI1_HUMAN
NC score	0.031106 (rank : 18)	θ value	1.06291 (rank : 17)
Query Neighborhood Hits	50	Target Neighborhood Hits	360	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

POLS_HUMAN
NC score	0.030441 (rank : 19)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	50	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XG87, O43289, Q9Y6C1	Gene names	POLS, TRF4
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7) (Topoisomerase-related function protein 4-1) (TRF4-1) (LAK-1) (DNA polymerase kappa).

POLS_MOUSE
NC score	0.027742 (rank : 20)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	50	Target Neighborhood Hits	91	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PB75	Gene names	Pols
Domain Architecture	No domain graphic available
Description	DNA polymerase sigma (EC 2.7.7.7).

DMXL1_MOUSE
NC score	0.025310 (rank : 21)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	50	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

NOTC4_MOUSE
NC score	0.024040 (rank : 22)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	50	Target Neighborhood Hits	872	Shared Neighborhood Hits	15
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

MATN2_MOUSE
NC score	0.022816 (rank : 23)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	50	Target Neighborhood Hits	356	Shared Neighborhood Hits	12
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

NCOR2_MOUSE
NC score	0.022644 (rank : 24)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	50	Target Neighborhood Hits	790	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

CELR3_MOUSE
NC score	0.020468 (rank : 25)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	50	Target Neighborhood Hits	687	Shared Neighborhood Hits	15
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

AFF4_MOUSE
NC score	0.020116 (rank : 26)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	50	Target Neighborhood Hits	581	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

NOTC2_HUMAN
NC score	0.019946 (rank : 27)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	50	Target Neighborhood Hits	1113	Shared Neighborhood Hits	21
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

EPIPL_HUMAN
NC score	0.019096 (rank : 28)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	50	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	P58107, Q76E58	Gene names	EPPK1, EPIPL
Domain Architecture
Description	Epiplakin (450 kDa epidermal antigen).

VASP_MOUSE
NC score	0.018812 (rank : 29)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	50	Target Neighborhood Hits	195	Shared Neighborhood Hits	5
SwissProt Accessions	P70460, Q3TAP0, Q3TCD2, Q3U0C2, Q3UDF1, Q91VD2, Q9R214	Gene names	Vasp
Domain Architecture
Description	Vasodilator-stimulated phosphoprotein (VASP).

LRP1_HUMAN
NC score	0.018572 (rank : 30)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	50	Target Neighborhood Hits	617	Shared Neighborhood Hits	14
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

ATBF1_MOUSE
NC score	0.018494 (rank : 31)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	50	Target Neighborhood Hits	1841	Shared Neighborhood Hits	16
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CPXM2_MOUSE
NC score	0.016596 (rank : 32)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	50	Target Neighborhood Hits	58	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

ENTK_HUMAN
NC score	0.015905 (rank : 33)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	50	Target Neighborhood Hits	310	Shared Neighborhood Hits	6
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ATBF1_HUMAN
NC score	0.014658 (rank : 34)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	50	Target Neighborhood Hits	1547	Shared Neighborhood Hits	11
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

VITRN_MOUSE
NC score	0.012776 (rank : 35)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	50	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

BPTF_HUMAN
NC score	0.012301 (rank : 36)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	50	Target Neighborhood Hits	786	Shared Neighborhood Hits	8
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DDX55_MOUSE
NC score	0.012204 (rank : 37)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	50	Target Neighborhood Hits	111	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPL9, Q149H5, Q3U460, Q8BZR1	Gene names	Ddx55, Kiaa1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

DDX55_HUMAN
NC score	0.012188 (rank : 38)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	50	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHQ9, Q658L6, Q9HCH7	Gene names	DDX55, KIAA1595
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX55 (EC 3.6.1.-) (DEAD box protein 55).

ANR38_MOUSE
NC score	0.011959 (rank : 39)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	50	Target Neighborhood Hits	512	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ZN687_MOUSE
NC score	0.011900 (rank : 40)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	50	Target Neighborhood Hits	913	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D2D7, Q6PAP3, Q6ZPQ9	Gene names	Znf687, Kiaa1441, Zfp687
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

SL9A3_HUMAN
NC score	0.011750 (rank : 41)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	50	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	P48764	Gene names	SLC9A3, NHE3
Domain Architecture
Description	Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3).

FAT2_HUMAN
NC score	0.011027 (rank : 42)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	50	Target Neighborhood Hits	507	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

AT11A_MOUSE
NC score	0.010593 (rank : 43)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	50	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P98197	Gene names	Atp11a
Domain Architecture
Description	Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase class I type 11A) (ATPase IS).

DOCK3_HUMAN
NC score	0.009988 (rank : 44)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	50	Target Neighborhood Hits	87	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZD9, O15017	Gene names	DOCK3, KIAA0299, MOCA
Domain Architecture
Description	Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP protein).

EZH1_MOUSE
NC score	0.009741 (rank : 45)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	50	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

PHLPP_HUMAN
NC score	0.008721 (rank : 46)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	50	Target Neighborhood Hits	604	Shared Neighborhood Hits	8
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

GAK6_HUMAN
NC score	0.005181 (rank : 47)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	50	Target Neighborhood Hits	392	Shared Neighborhood Hits	5
SwissProt Accessions	P62685	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K115 Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CDX2_MOUSE
NC score	0.005160 (rank : 48)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	50	Target Neighborhood Hits	336	Shared Neighborhood Hits	5
SwissProt Accessions	P43241	Gene names	Cdx2, Cdx-2
Domain Architecture
Description	Homeobox protein CDX-2 (Caudal-type homeobox protein 2).

PTN21_MOUSE
NC score	0.005135 (rank : 49)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	50	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

ZNF32_HUMAN
NC score	-0.000068 (rank : 50)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	50	Target Neighborhood Hits	735	Shared Neighborhood Hits	5
SwissProt Accessions	P17041, Q92951	Gene names	ZNF32, KOX30
Domain Architecture	No domain graphic available
Description	Zinc finger protein 32 (Zinc finger protein KOX30) (C2H2-546).