Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : XPP2_HUMAN

For an explanation of this page, click here

XPP2_HUMAN
SwissProt Accessions	O43895, O75994	Gene names	XPNPEP2
Domain Architecture
Description	Xaa-Pro aminopeptidase 2 precursor (EC 3.4.11.9) (X-Pro aminopeptidase 2) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane- bound AmP) (mAmP) (Aminoacylproline aminopeptidase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

XPP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O43895, O75994	Gene names	XPNPEP2
Domain Architecture
Description	Xaa-Pro aminopeptidase 2 precursor (EC 3.4.11.9) (X-Pro aminopeptidase 2) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane- bound AmP) (mAmP) (Aminoacylproline aminopeptidase).

XPP1_HUMAN
θ value	4.90052e-139 (rank : 2)	NC score	0.959847 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQW7, O15250, Q53EX6, Q8N3Q0, Q96D23	Gene names	XPNPEP1, XPNPEPL
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

XPP1_MOUSE
θ value	1.86219e-138 (rank : 3)	NC score	0.961270 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1B1, Q91Y37	Gene names	Xpnpep1
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

PEPD_HUMAN
θ value	0.00102713 (rank : 4)	NC score	0.248397 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P12955, Q8TBN9, Q9BT75	Gene names	PEPD, PRD
Domain Architecture
Description	Xaa-Pro dipeptidase (EC 3.4.13.9) (X-Pro dipeptidase) (Proline dipeptidase) (Prolidase) (Imidodipeptidase).

PEPD_MOUSE
θ value	0.0736092 (rank : 5)	NC score	0.220883 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q11136, P97735, Q3TH86, Q9CWK4	Gene names	Pepd, Pep4
Domain Architecture
Description	Xaa-Pro dipeptidase (EC 3.4.13.9) (X-Pro dipeptidase) (Proline dipeptidase) (Prolidase) (Imidodipeptidase) (Peptidase 4).

VGFR1_MOUSE
θ value	0.813845 (rank : 6)	NC score	0.006030 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	1118	Shared Neighborhood Hits	2
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

IMPG1_MOUSE
θ value	1.81305 (rank : 7)	NC score	0.033478 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

PHC1_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.018134 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	227	Shared Neighborhood Hits	2
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

ADA24_MOUSE
θ value	8.99809 (rank : 9)	NC score	0.003996 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	230	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

PTN5_MOUSE
θ value	8.99809 (rank : 10)	NC score	0.004518 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

Hits sorted by NC score

XPP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	O43895, O75994	Gene names	XPNPEP2
Domain Architecture
Description	Xaa-Pro aminopeptidase 2 precursor (EC 3.4.11.9) (X-Pro aminopeptidase 2) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane- bound AmP) (mAmP) (Aminoacylproline aminopeptidase).

XPP1_MOUSE
NC score	0.961270 (rank : 2)	θ value	1.86219e-138 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P1B1, Q91Y37	Gene names	Xpnpep1
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

XPP1_HUMAN
NC score	0.959847 (rank : 3)	θ value	4.90052e-139 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQW7, O15250, Q53EX6, Q8N3Q0, Q96D23	Gene names	XPNPEP1, XPNPEPL
Domain Architecture	No domain graphic available
Description	Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (X-Pro aminopeptidase 1) (X- prolyl aminopeptidase 1, soluble) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (Aminoacylproline aminopeptidase).

PEPD_HUMAN
NC score	0.248397 (rank : 4)	θ value	0.00102713 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P12955, Q8TBN9, Q9BT75	Gene names	PEPD, PRD
Domain Architecture
Description	Xaa-Pro dipeptidase (EC 3.4.13.9) (X-Pro dipeptidase) (Proline dipeptidase) (Prolidase) (Imidodipeptidase).

PEPD_MOUSE
NC score	0.220883 (rank : 5)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q11136, P97735, Q3TH86, Q9CWK4	Gene names	Pepd, Pep4
Domain Architecture
Description	Xaa-Pro dipeptidase (EC 3.4.13.9) (X-Pro dipeptidase) (Proline dipeptidase) (Prolidase) (Imidodipeptidase) (Peptidase 4).

IMPG1_MOUSE
NC score	0.033478 (rank : 6)	θ value	1.81305 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

PHC1_HUMAN
NC score	0.018134 (rank : 7)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	227	Shared Neighborhood Hits	2
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

VGFR1_MOUSE
NC score	0.006030 (rank : 8)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	1118	Shared Neighborhood Hits	2
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

PTN5_MOUSE
NC score	0.004518 (rank : 9)	θ value	8.99809 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

ADA24_MOUSE
NC score	0.003996 (rank : 10)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	230	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).