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Network neighborhood for query Sequence : IMPG1_HUMAN

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IMPG1_HUMAN
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IMPG1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

IMPG1_MOUSE
θ value	0 (rank : 2)	NC score	0.961032 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

MUC1_HUMAN
θ value	9.92553e-07 (rank : 3)	NC score	0.066320 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	975	Shared Neighborhood Hits	9
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

GP110_HUMAN
θ value	0.00228821 (rank : 4)	NC score	0.093028 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

ENTK_HUMAN
θ value	0.00869519 (rank : 5)	NC score	0.024302 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	310	Shared Neighborhood Hits	5
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

GOGA3_HUMAN
θ value	0.0252991 (rank : 6)	NC score	0.037232 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	1317	Shared Neighborhood Hits	17
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

STAB1_MOUSE
θ value	0.0252991 (rank : 7)	NC score	0.074102 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	566	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB1_HUMAN
θ value	0.0431538 (rank : 8)	NC score	0.073146 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	546	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

GP116_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.071706 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

MUC1_MOUSE
θ value	0.125558 (rank : 10)	NC score	0.151453 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	388	Shared Neighborhood Hits	8
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

UROL1_HUMAN
θ value	0.125558 (rank : 11)	NC score	0.100803 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	213	Shared Neighborhood Hits	17
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

EGF_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.061414 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	343	Shared Neighborhood Hits	27
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

MEGF6_HUMAN
θ value	0.21417 (rank : 13)	NC score	0.049679 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	671	Shared Neighborhood Hits	26
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TRI66_HUMAN
θ value	0.21417 (rank : 14)	NC score	0.033704 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	479	Shared Neighborhood Hits	10
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

E41L3_MOUSE
θ value	0.365318 (rank : 15)	NC score	0.020419 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	250	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

LAMA3_MOUSE
θ value	0.47712 (rank : 16)	NC score	0.039465 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	859	Shared Neighborhood Hits	34
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

NOTC4_MOUSE
θ value	0.47712 (rank : 17)	NC score	0.047709 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	872	Shared Neighborhood Hits	27
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

GOGA3_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.031103 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	1437	Shared Neighborhood Hits	19
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

PDLI2_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.028579 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	220	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

TOP2A_MOUSE
θ value	0.62314 (rank : 20)	NC score	0.031160 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

CELR3_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.031714 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	687	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

LEG8_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.029692 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	O00214, O15215, Q96B92, Q9H584, Q9H585, Q9UEZ6, Q9UP32, Q9UP33, Q9UP34	Gene names	LGALS8
Domain Architecture
Description	Galectin-8 (Gal-8) (Prostate carcinoma tumor antigen 1) (PCTA-1) (Po66 carbohydrate-binding protein) (Po66-CBP).

STAB2_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.064860 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	534	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

CCNB3_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.030137 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	368	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

EPHB4_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.005510 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	1013	Shared Neighborhood Hits	15
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

PCX1_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.038169 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

PRGC2_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.034342 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

UROL1_MOUSE
θ value	1.06291 (rank : 28)	NC score	0.063869 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	235	Shared Neighborhood Hits	20
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ZAN_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.063725 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	808	Shared Neighborhood Hits	29
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ZN509_MOUSE
θ value	1.06291 (rank : 30)	NC score	0.002322 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	990	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

DLEC1_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.038932 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BLA1	Gene names	Dlec1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 homolog.

EGF_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.058206 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	358	Shared Neighborhood Hits	26
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

UBP12_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.016462 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

CYTA_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.035988 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P01040	Gene names	CSTA, STF1
Domain Architecture
Description	Cystatin A (Stefin A) (Cystatin AS).

NOTC1_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.043752 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	916	Shared Neighborhood Hits	26
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC4_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.044241 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	905	Shared Neighborhood Hits	26
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

PPR3A_HUMAN
θ value	1.81305 (rank : 37)	NC score	0.032976 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q16821, O43476, Q75LN8, Q7KYM8, Q86UI6	Gene names	PPP1R3A, PP1G
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit).

TIM_MOUSE
θ value	1.81305 (rank : 38)	NC score	0.032447 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1X4, Q63ZX9, Q6P204, Q6PDL4, Q7TPV8, Q8R0Q2, Q9R268, Q9Z0E7	Gene names	Timeless, Tim1, Timeless1
Domain Architecture	No domain graphic available
Description	Timeless homolog (mTim).

AKAP9_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.021461 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	1710	Shared Neighborhood Hits	18
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CRUM1_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.054275 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	444	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

MYH2_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.016537 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	1491	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH7_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.016337 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	1559	Shared Neighborhood Hits	15
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

SMOO_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.026939 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	391	Shared Neighborhood Hits	10
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

NOTC2_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.041776 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	1069	Shared Neighborhood Hits	28
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ROCK1_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.007628 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	2126	Shared Neighborhood Hits	15
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SON_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.027866 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	957	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

GP110_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.050972 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

PTC2_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.016319 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

A1ATR_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.005757 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	P20848	Gene names	SERPINA2, ARGS, ATR, PIL
Domain Architecture
Description	Alpha-1-antitrypsin-related protein precursor.

CBP_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.021559 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	1051	Shared Neighborhood Hits	14
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CRUM1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.047964 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	457	Shared Neighborhood Hits	27
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FBLN2_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.040559 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	505	Shared Neighborhood Hits	28
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LPHN2_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.021302 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

MYH8_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.015493 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	1600	Shared Neighborhood Hits	17
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

RIMB2_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.013826 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	246	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SLIT3_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.032646 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	682	Shared Neighborhood Hits	24
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.031983 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	700	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ZAN_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.044737 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	679	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

C1QR1_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.040386 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	493	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CDN1C_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.039502 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

CEP57_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.019492 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	576	Shared Neighborhood Hits	12
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

GOGA4_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.016794 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	2034	Shared Neighborhood Hits	22
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HDAC5_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.009709 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	310	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

JPH3_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.010427 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ET77, Q9EQZ2	Gene names	Jph3, Jp3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

PCNT_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.018371 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	1551	Shared Neighborhood Hits	18
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CASP_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.014572 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	1152	Shared Neighborhood Hits	15
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CF153_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.026695 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EU6, Q9BRF6, Q9P0C8	Gene names	C6orf153
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153.

CF153_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.025006 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UFY0, Q91X71	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153 homolog.

ELOA1_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.011055 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

FA21C_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.016921 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

FBN1_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.040566 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	563	Shared Neighborhood Hits	26
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

KIF5A_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.009353 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	843	Shared Neighborhood Hits	14
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

MCR_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.005216 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

SI1L3_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.009073 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	305	Shared Neighborhood Hits	5
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SLIT2_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.032475 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	708	Shared Neighborhood Hits	25
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LCE1D_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.056837 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

STAB2_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.058722 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	528	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

Hits sorted by NC score

IMPG1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

IMPG1_MOUSE
NC score	0.961032 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R1W8, Q9CTP8, Q9ES62, Q9ET31	Gene names	Impg1, Spacr
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (IPM 150 proteoglycan) (Sialoprotein associated with cones and rods).

MUC1_MOUSE
NC score	0.151453 (rank : 3)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	388	Shared Neighborhood Hits	8
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

UROL1_HUMAN
NC score	0.100803 (rank : 4)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	213	Shared Neighborhood Hits	17
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

GP110_HUMAN
NC score	0.093028 (rank : 5)	θ value	0.00228821 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

STAB1_MOUSE
NC score	0.074102 (rank : 6)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	566	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB1_HUMAN
NC score	0.073146 (rank : 7)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	546	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

GP116_HUMAN
NC score	0.071706 (rank : 8)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	167	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

MUC1_HUMAN
NC score	0.066320 (rank : 9)	θ value	9.92553e-07 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	975	Shared Neighborhood Hits	9
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

STAB2_HUMAN
NC score	0.064860 (rank : 10)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	534	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

UROL1_MOUSE
NC score	0.063869 (rank : 11)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	235	Shared Neighborhood Hits	20
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ZAN_MOUSE
NC score	0.063725 (rank : 12)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	808	Shared Neighborhood Hits	29
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

EGF_HUMAN
NC score	0.061414 (rank : 13)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	343	Shared Neighborhood Hits	27
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

STAB2_MOUSE
NC score	0.058722 (rank : 14)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	528	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

EGF_MOUSE
NC score	0.058206 (rank : 15)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	358	Shared Neighborhood Hits	26
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

LCE1D_HUMAN
NC score	0.056837 (rank : 16)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

CRUM1_MOUSE
NC score	0.054275 (rank : 17)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	444	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

GP110_MOUSE
NC score	0.050972 (rank : 18)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

MEGF6_HUMAN
NC score	0.049679 (rank : 19)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	671	Shared Neighborhood Hits	26
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

CRUM1_HUMAN
NC score	0.047964 (rank : 20)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	457	Shared Neighborhood Hits	27
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

NOTC4_MOUSE
NC score	0.047709 (rank : 21)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	872	Shared Neighborhood Hits	27
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ZAN_HUMAN
NC score	0.044737 (rank : 22)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	679	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

NOTC4_HUMAN
NC score	0.044241 (rank : 23)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	905	Shared Neighborhood Hits	26
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC1_MOUSE
NC score	0.043752 (rank : 24)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	916	Shared Neighborhood Hits	26
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
NC score	0.041776 (rank : 25)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	1069	Shared Neighborhood Hits	28
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FBN1_MOUSE
NC score	0.040566 (rank : 26)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	563	Shared Neighborhood Hits	26
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBLN2_MOUSE
NC score	0.040559 (rank : 27)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	505	Shared Neighborhood Hits	28
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

C1QR1_HUMAN
NC score	0.040386 (rank : 28)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	493	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CDN1C_HUMAN
NC score	0.039502 (rank : 29)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	168	Shared Neighborhood Hits	6
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

LAMA3_MOUSE
NC score	0.039465 (rank : 30)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	859	Shared Neighborhood Hits	34
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

DLEC1_MOUSE
NC score	0.038932 (rank : 31)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BLA1	Gene names	Dlec1
Domain Architecture	No domain graphic available
Description	Deleted in lung and esophageal cancer protein 1 homolog.

PCX1_HUMAN
NC score	0.038169 (rank : 32)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

GOGA3_HUMAN
NC score	0.037232 (rank : 33)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	1317	Shared Neighborhood Hits	17
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

CYTA_HUMAN
NC score	0.035988 (rank : 34)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P01040	Gene names	CSTA, STF1
Domain Architecture
Description	Cystatin A (Stefin A) (Cystatin AS).

PRGC2_MOUSE
NC score	0.034342 (rank : 35)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	225	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

TRI66_HUMAN
NC score	0.033704 (rank : 36)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	479	Shared Neighborhood Hits	10
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PPR3A_HUMAN
NC score	0.032976 (rank : 37)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q16821, O43476, Q75LN8, Q7KYM8, Q86UI6	Gene names	PPP1R3A, PP1G
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit).

SLIT3_HUMAN
NC score	0.032646 (rank : 38)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	682	Shared Neighborhood Hits	24
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT2_HUMAN
NC score	0.032475 (rank : 39)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	708	Shared Neighborhood Hits	25
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TIM_MOUSE
NC score	0.032447 (rank : 40)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1X4, Q63ZX9, Q6P204, Q6PDL4, Q7TPV8, Q8R0Q2, Q9R268, Q9Z0E7	Gene names	Timeless, Tim1, Timeless1
Domain Architecture	No domain graphic available
Description	Timeless homolog (mTim).

SLIT3_MOUSE
NC score	0.031983 (rank : 41)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	700	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

CELR3_MOUSE
NC score	0.031714 (rank : 42)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	687	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

TOP2A_MOUSE
NC score	0.031160 (rank : 43)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

GOGA3_MOUSE
NC score	0.031103 (rank : 44)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	1437	Shared Neighborhood Hits	19
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

CCNB3_HUMAN
NC score	0.030137 (rank : 45)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	368	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

LEG8_HUMAN
NC score	0.029692 (rank : 46)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	O00214, O15215, Q96B92, Q9H584, Q9H585, Q9UEZ6, Q9UP32, Q9UP33, Q9UP34	Gene names	LGALS8
Domain Architecture
Description	Galectin-8 (Gal-8) (Prostate carcinoma tumor antigen 1) (PCTA-1) (Po66 carbohydrate-binding protein) (Po66-CBP).

PDLI2_MOUSE
NC score	0.028579 (rank : 47)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	220	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1G6	Gene names	Pdlim2
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).

SON_MOUSE
NC score	0.027866 (rank : 48)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	957	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SMOO_HUMAN
NC score	0.026939 (rank : 49)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	391	Shared Neighborhood Hits	10
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CF153_HUMAN
NC score	0.026695 (rank : 50)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EU6, Q9BRF6, Q9P0C8	Gene names	C6orf153
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153.

CF153_MOUSE
NC score	0.025006 (rank : 51)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	78	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UFY0, Q91X71	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf153 homolog.

ENTK_HUMAN
NC score	0.024302 (rank : 52)	θ value	0.00869519 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	310	Shared Neighborhood Hits	5
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

CBP_MOUSE
NC score	0.021559 (rank : 53)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	1051	Shared Neighborhood Hits	14
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

AKAP9_HUMAN
NC score	0.021461 (rank : 54)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	1710	Shared Neighborhood Hits	18
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

LPHN2_HUMAN
NC score	0.021302 (rank : 55)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

E41L3_MOUSE
NC score	0.020419 (rank : 56)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	250	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WV92, Q9R102	Gene names	Epb41l3, Dal1, Epb4.1l3
Domain Architecture
Description	Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (DAL1P) (mDAL-1).

CEP57_HUMAN
NC score	0.019492 (rank : 57)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	576	Shared Neighborhood Hits	12
SwissProt Accessions	Q86XR8, Q14704, Q8IXP0, Q9BVF9	Gene names	CEP57, KIAA0092, TSP57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin) (FGF2-interacting protein).

PCNT_HUMAN
NC score	0.018371 (rank : 58)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	1551	Shared Neighborhood Hits	18
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

FA21C_HUMAN
NC score	0.016921 (rank : 59)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

GOGA4_HUMAN
NC score	0.016794 (rank : 60)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	2034	Shared Neighborhood Hits	22
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MYH2_HUMAN
NC score	0.016537 (rank : 61)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	1491	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

UBP12_HUMAN
NC score	0.016462 (rank : 62)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

MYH7_HUMAN
NC score	0.016337 (rank : 63)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	1559	Shared Neighborhood Hits	15
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PTC2_HUMAN
NC score	0.016319 (rank : 64)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	63	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6C5, O95341, O95856, Q5QP87, Q6UX14	Gene names	PTCH2
Domain Architecture
Description	Protein patched homolog 2 (PTC2).

MYH8_MOUSE
NC score	0.015493 (rank : 65)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	1600	Shared Neighborhood Hits	17
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CASP_MOUSE
NC score	0.014572 (rank : 66)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	1152	Shared Neighborhood Hits	15
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

RIMB2_MOUSE
NC score	0.013826 (rank : 67)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	246	Shared Neighborhood Hits	3
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ELOA1_MOUSE
NC score	0.011055 (rank : 68)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	152	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CB77, Q80VB2, Q9R0Q5	Gene names	Tceb3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

JPH3_MOUSE
NC score	0.010427 (rank : 69)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ET77, Q9EQZ2	Gene names	Jph3, Jp3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

HDAC5_MOUSE
NC score	0.009709 (rank : 70)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	310	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z2V6, Q9JL73	Gene names	Hdac5
Domain Architecture
Description	Histone deacetylase 5 (HD5) (Histone deacetylase mHDA1).

KIF5A_HUMAN
NC score	0.009353 (rank : 71)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	843	Shared Neighborhood Hits	14
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

SI1L3_HUMAN
NC score	0.009073 (rank : 72)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	305	Shared Neighborhood Hits	5
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

ROCK1_MOUSE
NC score	0.007628 (rank : 73)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	2126	Shared Neighborhood Hits	15
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

A1ATR_HUMAN
NC score	0.005757 (rank : 74)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	P20848	Gene names	SERPINA2, ARGS, ATR, PIL
Domain Architecture
Description	Alpha-1-antitrypsin-related protein precursor.

EPHB4_MOUSE
NC score	0.005510 (rank : 75)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	1013	Shared Neighborhood Hits	15
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

MCR_MOUSE
NC score	0.005216 (rank : 76)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

ZN509_MOUSE
NC score	0.002322 (rank : 77)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	990	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.