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Network neighborhood for query Sequence : MEGF6_HUMAN

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MEGF6_HUMAN
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MEGF6_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	671	Target Neighborhood Hits	671	Shared Neighborhood Hits	671
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NOTC2_MOUSE
θ value	1.06727e-101 (rank : 2)	NC score	0.829493 (rank : 50)
Query Neighborhood Hits	671	Target Neighborhood Hits	1069	Shared Neighborhood Hits	467
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	6.06035e-97 (rank : 3)	NC score	0.837476 (rank : 46)
Query Neighborhood Hits	671	Target Neighborhood Hits	1062	Shared Neighborhood Hits	505
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	1.03374e-96 (rank : 4)	NC score	0.836228 (rank : 47)
Query Neighborhood Hits	671	Target Neighborhood Hits	975	Shared Neighborhood Hits	486
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
θ value	3.1125e-93 (rank : 5)	NC score	0.827389 (rank : 52)
Query Neighborhood Hits	671	Target Neighborhood Hits	1113	Shared Neighborhood Hits	487
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_MOUSE
θ value	1.18275e-92 (rank : 6)	NC score	0.858295 (rank : 31)
Query Neighborhood Hits	671	Target Neighborhood Hits	916	Shared Neighborhood Hits	477
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_HUMAN
θ value	3.22093e-90 (rank : 7)	NC score	0.835520 (rank : 48)
Query Neighborhood Hits	671	Target Neighborhood Hits	906	Shared Neighborhood Hits	467
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC4_HUMAN
θ value	4.65103e-89 (rank : 8)	NC score	0.818515 (rank : 56)
Query Neighborhood Hits	671	Target Neighborhood Hits	905	Shared Neighborhood Hits	491
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	5.14231e-88 (rank : 9)	NC score	0.817997 (rank : 57)
Query Neighborhood Hits	671	Target Neighborhood Hits	872	Shared Neighborhood Hits	481
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

SREC_HUMAN
θ value	3.44927e-84 (rank : 10)	NC score	0.888455 (rank : 12)
Query Neighborhood Hits	671	Target Neighborhood Hits	645	Shared Neighborhood Hits	456
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

FBN3_HUMAN
θ value	2.73302e-81 (rank : 11)	NC score	0.899381 (rank : 4)
Query Neighborhood Hits	671	Target Neighborhood Hits	543	Shared Neighborhood Hits	450
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

SREC2_HUMAN
θ value	9.0981e-77 (rank : 12)	NC score	0.865088 (rank : 27)
Query Neighborhood Hits	671	Target Neighborhood Hits	645	Shared Neighborhood Hits	420
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	1.18825e-76 (rank : 13)	NC score	0.877217 (rank : 17)
Query Neighborhood Hits	671	Target Neighborhood Hits	605	Shared Neighborhood Hits	422
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

FBN2_MOUSE
θ value	2.56397e-71 (rank : 14)	NC score	0.894370 (rank : 10)
Query Neighborhood Hits	671	Target Neighborhood Hits	549	Shared Neighborhood Hits	466
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_HUMAN
θ value	3.34864e-71 (rank : 15)	NC score	0.896225 (rank : 6)
Query Neighborhood Hits	671	Target Neighborhood Hits	560	Shared Neighborhood Hits	465
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_HUMAN
θ value	3.13423e-69 (rank : 16)	NC score	0.895216 (rank : 9)
Query Neighborhood Hits	671	Target Neighborhood Hits	557	Shared Neighborhood Hits	463
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

TENX_HUMAN
θ value	2.24614e-67 (rank : 17)	NC score	0.689300 (rank : 109)
Query Neighborhood Hits	671	Target Neighborhood Hits	789	Shared Neighborhood Hits	426
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

FBN1_MOUSE
θ value	7.98882e-65 (rank : 18)	NC score	0.895648 (rank : 7)
Query Neighborhood Hits	671	Target Neighborhood Hits	563	Shared Neighborhood Hits	466
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

MATN2_MOUSE
θ value	2.32439e-64 (rank : 19)	NC score	0.761163 (rank : 82)
Query Neighborhood Hits	671	Target Neighborhood Hits	356	Shared Neighborhood Hits	278
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_HUMAN
θ value	5.7252e-63 (rank : 20)	NC score	0.770539 (rank : 80)
Query Neighborhood Hits	671	Target Neighborhood Hits	365	Shared Neighborhood Hits	281
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

SCUB3_HUMAN
θ value	5.7252e-63 (rank : 21)	NC score	0.850300 (rank : 39)
Query Neighborhood Hits	671	Target Neighborhood Hits	428	Shared Neighborhood Hits	343
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	1.27544e-62 (rank : 22)	NC score	0.851346 (rank : 38)
Query Neighborhood Hits	671	Target Neighborhood Hits	442	Shared Neighborhood Hits	349
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

JAG2_HUMAN
θ value	1.0458e-56 (rank : 23)	NC score	0.899130 (rank : 5)
Query Neighborhood Hits	671	Target Neighborhood Hits	491	Shared Neighborhood Hits	428
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

TENA_MOUSE
θ value	5.19021e-56 (rank : 24)	NC score	0.690672 (rank : 108)
Query Neighborhood Hits	671	Target Neighborhood Hits	596	Shared Neighborhood Hits	380
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENA_HUMAN
θ value	6.77864e-56 (rank : 25)	NC score	0.697041 (rank : 106)
Query Neighborhood Hits	671	Target Neighborhood Hits	631	Shared Neighborhood Hits	399
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LTB1L_HUMAN
θ value	4.39379e-55 (rank : 26)	NC score	0.860445 (rank : 28)
Query Neighborhood Hits	671	Target Neighborhood Hits	553	Shared Neighborhood Hits	399
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	4.39379e-55 (rank : 27)	NC score	0.859187 (rank : 30)
Query Neighborhood Hits	671	Target Neighborhood Hits	502	Shared Neighborhood Hits	394
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	1.66964e-54 (rank : 28)	NC score	0.856703 (rank : 33)
Query Neighborhood Hits	671	Target Neighborhood Hits	514	Shared Neighborhood Hits	404
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	1.66964e-54 (rank : 29)	NC score	0.856119 (rank : 34)
Query Neighborhood Hits	671	Target Neighborhood Hits	479	Shared Neighborhood Hits	389
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

JAG2_MOUSE
θ value	2.18062e-54 (rank : 30)	NC score	0.893963 (rank : 11)
Query Neighborhood Hits	671	Target Neighborhood Hits	504	Shared Neighborhood Hits	426
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

FBLN1_HUMAN
θ value	4.85792e-54 (rank : 31)	NC score	0.828942 (rank : 51)
Query Neighborhood Hits	671	Target Neighborhood Hits	324	Shared Neighborhood Hits	308
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

JAG1_HUMAN
θ value	1.08223e-53 (rank : 32)	NC score	0.899875 (rank : 2)
Query Neighborhood Hits	671	Target Neighborhood Hits	514	Shared Neighborhood Hits	433
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	1.19655e-52 (rank : 33)	NC score	0.899756 (rank : 3)
Query Neighborhood Hits	671	Target Neighborhood Hits	518	Shared Neighborhood Hits	428
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

LTBP3_HUMAN
θ value	1.19655e-52 (rank : 34)	NC score	0.871990 (rank : 19)
Query Neighborhood Hits	671	Target Neighborhood Hits	502	Shared Neighborhood Hits	403
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBLN1_MOUSE
θ value	2.041e-52 (rank : 35)	NC score	0.833151 (rank : 49)
Query Neighborhood Hits	671	Target Neighborhood Hits	329	Shared Neighborhood Hits	308
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LTBP4_MOUSE
θ value	4.54686e-52 (rank : 36)	NC score	0.895452 (rank : 8)
Query Neighborhood Hits	671	Target Neighborhood Hits	607	Shared Neighborhood Hits	410
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LAMA5_HUMAN
θ value	2.25659e-51 (rank : 37)	NC score	0.713771 (rank : 98)
Query Neighborhood Hits	671	Target Neighborhood Hits	976	Shared Neighborhood Hits	419
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LTBP2_HUMAN
θ value	8.57503e-51 (rank : 38)	NC score	0.881304 (rank : 14)
Query Neighborhood Hits	671	Target Neighborhood Hits	552	Shared Neighborhood Hits	423
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_MOUSE
θ value	8.02596e-49 (rank : 39)	NC score	0.869863 (rank : 21)
Query Neighborhood Hits	671	Target Neighborhood Hits	475	Shared Neighborhood Hits	397
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LAMA5_MOUSE
θ value	1.36902e-48 (rank : 40)	NC score	0.727666 (rank : 92)
Query Neighborhood Hits	671	Target Neighborhood Hits	828	Shared Neighborhood Hits	417
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FBLN2_HUMAN
θ value	2.3352e-48 (rank : 41)	NC score	0.849201 (rank : 40)
Query Neighborhood Hits	671	Target Neighborhood Hits	392	Shared Neighborhood Hits	306
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	4.40402e-47 (rank : 42)	NC score	0.841765 (rank : 45)
Query Neighborhood Hits	671	Target Neighborhood Hits	505	Shared Neighborhood Hits	329
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LTBP2_MOUSE
θ value	4.40402e-47 (rank : 43)	NC score	0.878949 (rank : 15)
Query Neighborhood Hits	671	Target Neighborhood Hits	617	Shared Neighborhood Hits	418
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LAMA2_HUMAN
θ value	1.41672e-45 (rank : 44)	NC score	0.634191 (rank : 137)
Query Neighborhood Hits	671	Target Neighborhood Hits	1092	Shared Neighborhood Hits	377
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	2.95404e-43 (rank : 45)	NC score	0.601272 (rank : 160)
Query Neighborhood Hits	671	Target Neighborhood Hits	1198	Shared Neighborhood Hits	377
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB2_HUMAN
θ value	4.2656e-42 (rank : 46)	NC score	0.697754 (rank : 105)
Query Neighborhood Hits	671	Target Neighborhood Hits	692	Shared Neighborhood Hits	340
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	9.50281e-42 (rank : 47)	NC score	0.691056 (rank : 107)
Query Neighborhood Hits	671	Target Neighborhood Hits	722	Shared Neighborhood Hits	338
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

HMCN1_HUMAN
θ value	1.2411e-41 (rank : 48)	NC score	0.501498 (rank : 210)
Query Neighborhood Hits	671	Target Neighborhood Hits	983	Shared Neighborhood Hits	359
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

USH2A_MOUSE
θ value	8.04462e-41 (rank : 49)	NC score	0.601552 (rank : 159)
Query Neighborhood Hits	671	Target Neighborhood Hits	626	Shared Neighborhood Hits	336
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LAMA1_HUMAN
θ value	1.3722e-40 (rank : 50)	NC score	0.680970 (rank : 111)
Query Neighborhood Hits	671	Target Neighborhood Hits	804	Shared Neighborhood Hits	373
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB1_MOUSE
θ value	2.34062e-40 (rank : 51)	NC score	0.640755 (rank : 135)
Query Neighborhood Hits	671	Target Neighborhood Hits	919	Shared Neighborhood Hits	325
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_HUMAN
θ value	2.58786e-39 (rank : 52)	NC score	0.620515 (rank : 148)
Query Neighborhood Hits	671	Target Neighborhood Hits	1018	Shared Neighborhood Hits	341
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

FBLN5_MOUSE
θ value	4.41421e-39 (rank : 53)	NC score	0.809226 (rank : 64)
Query Neighborhood Hits	671	Target Neighborhood Hits	317	Shared Neighborhood Hits	295
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LAMA1_MOUSE
θ value	4.41421e-39 (rank : 54)	NC score	0.684641 (rank : 110)
Query Neighborhood Hits	671	Target Neighborhood Hits	838	Shared Neighborhood Hits	388
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

FBLN5_HUMAN
θ value	1.6774e-38 (rank : 55)	NC score	0.813634 (rank : 61)
Query Neighborhood Hits	671	Target Neighborhood Hits	329	Shared Neighborhood Hits	308
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

CRUM1_HUMAN
θ value	2.19075e-38 (rank : 56)	NC score	0.867837 (rank : 24)
Query Neighborhood Hits	671	Target Neighborhood Hits	457	Shared Neighborhood Hits	398
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DLL4_MOUSE
θ value	1.08726e-37 (rank : 57)	NC score	0.867595 (rank : 25)
Query Neighborhood Hits	671	Target Neighborhood Hits	440	Shared Neighborhood Hits	390
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_HUMAN
θ value	1.42001e-37 (rank : 58)	NC score	0.868409 (rank : 22)
Query Neighborhood Hits	671	Target Neighborhood Hits	435	Shared Neighborhood Hits	382
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

C1QR1_MOUSE
θ value	2.26708e-35 (rank : 59)	NC score	0.821271 (rank : 55)
Query Neighborhood Hits	671	Target Neighborhood Hits	342	Shared Neighborhood Hits	303
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

MATN4_HUMAN
θ value	1.9192e-34 (rank : 60)	NC score	0.666117 (rank : 119)
Query Neighborhood Hits	671	Target Neighborhood Hits	287	Shared Neighborhood Hits	242
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

LAMC3_HUMAN
θ value	9.52487e-34 (rank : 61)	NC score	0.675471 (rank : 115)
Query Neighborhood Hits	671	Target Neighborhood Hits	588	Shared Neighborhood Hits	352
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

C1QR1_HUMAN
θ value	1.24399e-33 (rank : 62)	NC score	0.826107 (rank : 53)
Query Neighborhood Hits	671	Target Neighborhood Hits	493	Shared Neighborhood Hits	330
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

USH2A_HUMAN
θ value	1.6247e-33 (rank : 63)	NC score	0.569891 (rank : 179)
Query Neighborhood Hits	671	Target Neighborhood Hits	600	Shared Neighborhood Hits	305
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LAMC1_MOUSE
θ value	3.61944e-33 (rank : 64)	NC score	0.629147 (rank : 143)
Query Neighborhood Hits	671	Target Neighborhood Hits	856	Shared Neighborhood Hits	333
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

DLL1_HUMAN
θ value	6.17384e-33 (rank : 65)	NC score	0.877872 (rank : 16)
Query Neighborhood Hits	671	Target Neighborhood Hits	455	Shared Neighborhood Hits	404
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

CRUM1_MOUSE
θ value	8.06329e-33 (rank : 66)	NC score	0.870817 (rank : 20)
Query Neighborhood Hits	671	Target Neighborhood Hits	444	Shared Neighborhood Hits	390
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

MATN4_MOUSE
θ value	1.0531e-32 (rank : 67)	NC score	0.640004 (rank : 136)
Query Neighborhood Hits	671	Target Neighborhood Hits	277	Shared Neighborhood Hits	232
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

ZAN_MOUSE
θ value	1.0531e-32 (rank : 68)	NC score	0.672076 (rank : 117)
Query Neighborhood Hits	671	Target Neighborhood Hits	808	Shared Neighborhood Hits	475
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CRUM2_HUMAN
θ value	1.79631e-32 (rank : 69)	NC score	0.873833 (rank : 18)
Query Neighborhood Hits	671	Target Neighborhood Hits	453	Shared Neighborhood Hits	400
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

FBLN4_HUMAN
θ value	3.06405e-32 (rank : 70)	NC score	0.805562 (rank : 68)
Query Neighborhood Hits	671	Target Neighborhood Hits	278	Shared Neighborhood Hits	265
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

LAMC3_MOUSE
θ value	3.06405e-32 (rank : 71)	NC score	0.679668 (rank : 113)
Query Neighborhood Hits	671	Target Neighborhood Hits	624	Shared Neighborhood Hits	336
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

FBLN3_MOUSE
θ value	6.82597e-32 (rank : 72)	NC score	0.781829 (rank : 76)
Query Neighborhood Hits	671	Target Neighborhood Hits	279	Shared Neighborhood Hits	263
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_MOUSE
θ value	6.82597e-32 (rank : 73)	NC score	0.798872 (rank : 72)
Query Neighborhood Hits	671	Target Neighborhood Hits	270	Shared Neighborhood Hits	259
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

TIE1_HUMAN
θ value	6.82597e-32 (rank : 74)	NC score	0.259226 (rank : 331)
Query Neighborhood Hits	671	Target Neighborhood Hits	1241	Shared Neighborhood Hits	330
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TRBM_MOUSE
θ value	8.91499e-32 (rank : 75)	NC score	0.809946 (rank : 63)
Query Neighborhood Hits	671	Target Neighborhood Hits	361	Shared Neighborhood Hits	313
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

FBLN3_HUMAN
θ value	1.16434e-31 (rank : 76)	NC score	0.792044 (rank : 75)
Query Neighborhood Hits	671	Target Neighborhood Hits	293	Shared Neighborhood Hits	276
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

TIE1_MOUSE
θ value	5.77852e-31 (rank : 77)	NC score	0.253996 (rank : 337)
Query Neighborhood Hits	671	Target Neighborhood Hits	1266	Shared Neighborhood Hits	329
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TRBM_HUMAN
θ value	7.54701e-31 (rank : 78)	NC score	0.822252 (rank : 54)
Query Neighborhood Hits	671	Target Neighborhood Hits	339	Shared Neighborhood Hits	300
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

DLL1_MOUSE
θ value	9.8567e-31 (rank : 79)	NC score	0.882177 (rank : 13)
Query Neighborhood Hits	671	Target Neighborhood Hits	456	Shared Neighborhood Hits	412
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

MATN3_HUMAN
θ value	1.28732e-30 (rank : 80)	NC score	0.659636 (rank : 124)
Query Neighborhood Hits	671	Target Neighborhood Hits	268	Shared Neighborhood Hits	218
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

LAMC1_HUMAN
θ value	2.42779e-29 (rank : 81)	NC score	0.610800 (rank : 155)
Query Neighborhood Hits	671	Target Neighborhood Hits	922	Shared Neighborhood Hits	343
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

MATN3_MOUSE
θ value	3.17079e-29 (rank : 82)	NC score	0.659801 (rank : 122)
Query Neighborhood Hits	671	Target Neighborhood Hits	261	Shared Neighborhood Hits	221
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

TIE2_MOUSE
θ value	3.17079e-29 (rank : 83)	NC score	0.228540 (rank : 353)
Query Neighborhood Hits	671	Target Neighborhood Hits	1204	Shared Neighborhood Hits	313
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

DNER_HUMAN
θ value	1.2049e-28 (rank : 84)	NC score	0.868340 (rank : 23)
Query Neighborhood Hits	671	Target Neighborhood Hits	460	Shared Neighborhood Hits	385
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

EMR1_MOUSE
θ value	1.2049e-28 (rank : 85)	NC score	0.641559 (rank : 133)
Query Neighborhood Hits	671	Target Neighborhood Hits	349	Shared Neighborhood Hits	261
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

TIE2_HUMAN
θ value	2.68423e-28 (rank : 86)	NC score	0.228177 (rank : 354)
Query Neighborhood Hits	671	Target Neighborhood Hits	1192	Shared Neighborhood Hits	299
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

EGF_MOUSE
θ value	4.57862e-28 (rank : 87)	NC score	0.765105 (rank : 81)
Query Neighborhood Hits	671	Target Neighborhood Hits	358	Shared Neighborhood Hits	326
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

PCSK5_MOUSE
θ value	1.33217e-27 (rank : 88)	NC score	0.566816 (rank : 180)
Query Neighborhood Hits	671	Target Neighborhood Hits	613	Shared Neighborhood Hits	402
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

EGF_HUMAN
θ value	1.73987e-27 (rank : 89)	NC score	0.731325 (rank : 90)
Query Neighborhood Hits	671	Target Neighborhood Hits	343	Shared Neighborhood Hits	309
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

AGRIN_HUMAN
θ value	2.27234e-27 (rank : 90)	NC score	0.718347 (rank : 94)
Query Neighborhood Hits	671	Target Neighborhood Hits	582	Shared Neighborhood Hits	402
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

DNER_MOUSE
θ value	3.87602e-27 (rank : 91)	NC score	0.865254 (rank : 26)
Query Neighborhood Hits	671	Target Neighborhood Hits	413	Shared Neighborhood Hits	365
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

GAS6_HUMAN
θ value	3.87602e-27 (rank : 92)	NC score	0.811310 (rank : 62)
Query Neighborhood Hits	671	Target Neighborhood Hits	348	Shared Neighborhood Hits	316
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

NELL2_HUMAN
θ value	1.12775e-26 (rank : 93)	NC score	0.854250 (rank : 36)
Query Neighborhood Hits	671	Target Neighborhood Hits	449	Shared Neighborhood Hits	395
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

LAMA3_MOUSE
θ value	2.51237e-26 (rank : 94)	NC score	0.605444 (rank : 158)
Query Neighborhood Hits	671	Target Neighborhood Hits	859	Shared Neighborhood Hits	373
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

GAS6_MOUSE
θ value	7.30988e-26 (rank : 95)	NC score	0.806476 (rank : 67)
Query Neighborhood Hits	671	Target Neighborhood Hits	343	Shared Neighborhood Hits	314
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

LAMB3_HUMAN
θ value	7.30988e-26 (rank : 96)	NC score	0.598350 (rank : 163)
Query Neighborhood Hits	671	Target Neighborhood Hits	461	Shared Neighborhood Hits	221
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	1.62847e-25 (rank : 97)	NC score	0.632540 (rank : 140)
Query Neighborhood Hits	671	Target Neighborhood Hits	444	Shared Neighborhood Hits	248
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

CUBN_HUMAN
θ value	2.12685e-25 (rank : 98)	NC score	0.742931 (rank : 85)
Query Neighborhood Hits	671	Target Neighborhood Hits	482	Shared Neighborhood Hits	371
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

DLL3_HUMAN
θ value	2.12685e-25 (rank : 99)	NC score	0.848684 (rank : 41)
Query Neighborhood Hits	671	Target Neighborhood Hits	419	Shared Neighborhood Hits	372
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

NELL2_MOUSE
θ value	3.62785e-25 (rank : 100)	NC score	0.854746 (rank : 35)
Query Neighborhood Hits	671	Target Neighborhood Hits	436	Shared Neighborhood Hits	394
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

FRAS1_MOUSE
θ value	4.73814e-25 (rank : 101)	NC score	0.503546 (rank : 207)
Query Neighborhood Hits	671	Target Neighborhood Hits	747	Shared Neighborhood Hits	383
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CD97_HUMAN
θ value	6.18819e-25 (rank : 102)	NC score	0.651199 (rank : 128)
Query Neighborhood Hits	671	Target Neighborhood Hits	353	Shared Neighborhood Hits	266
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR2_HUMAN
θ value	1.37858e-24 (rank : 103)	NC score	0.659531 (rank : 125)
Query Neighborhood Hits	671	Target Neighborhood Hits	345	Shared Neighborhood Hits	263
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

CUBN_MOUSE
θ value	1.80048e-24 (rank : 104)	NC score	0.744735 (rank : 84)
Query Neighborhood Hits	671	Target Neighborhood Hits	477	Shared Neighborhood Hits	362
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

NELL1_HUMAN
θ value	6.84181e-24 (rank : 105)	NC score	0.857348 (rank : 32)
Query Neighborhood Hits	671	Target Neighborhood Hits	451	Shared Neighborhood Hits	390
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

PROS_HUMAN
θ value	1.16704e-23 (rank : 106)	NC score	0.802160 (rank : 71)
Query Neighborhood Hits	671	Target Neighborhood Hits	340	Shared Neighborhood Hits	312
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	1.16704e-23 (rank : 107)	NC score	0.796988 (rank : 73)
Query Neighborhood Hits	671	Target Neighborhood Hits	330	Shared Neighborhood Hits	302
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

STAB2_HUMAN
θ value	1.16704e-23 (rank : 108)	NC score	0.814949 (rank : 58)
Query Neighborhood Hits	671	Target Neighborhood Hits	534	Shared Neighborhood Hits	423
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

EGFL9_MOUSE
θ value	2.59989e-23 (rank : 109)	NC score	0.846212 (rank : 43)
Query Neighborhood Hits	671	Target Neighborhood Hits	379	Shared Neighborhood Hits	347
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EMR1_HUMAN
θ value	5.79196e-23 (rank : 110)	NC score	0.680278 (rank : 112)
Query Neighborhood Hits	671	Target Neighborhood Hits	382	Shared Neighborhood Hits	281
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

STAB2_MOUSE
θ value	5.79196e-23 (rank : 111)	NC score	0.808266 (rank : 65)
Query Neighborhood Hits	671	Target Neighborhood Hits	528	Shared Neighborhood Hits	425
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STAB1_HUMAN
θ value	7.56453e-23 (rank : 112)	NC score	0.814241 (rank : 60)
Query Neighborhood Hits	671	Target Neighborhood Hits	546	Shared Neighborhood Hits	431
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

DLL3_MOUSE
θ value	9.87957e-23 (rank : 113)	NC score	0.841974 (rank : 44)
Query Neighborhood Hits	671	Target Neighborhood Hits	399	Shared Neighborhood Hits	354
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EGFL9_HUMAN
θ value	2.20094e-22 (rank : 114)	NC score	0.847999 (rank : 42)
Query Neighborhood Hits	671	Target Neighborhood Hits	365	Shared Neighborhood Hits	342
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

STAB1_MOUSE
θ value	1.42661e-21 (rank : 115)	NC score	0.814259 (rank : 59)
Query Neighborhood Hits	671	Target Neighborhood Hits	566	Shared Neighborhood Hits	446
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

FRAS1_HUMAN
θ value	9.24701e-21 (rank : 116)	NC score	0.524567 (rank : 200)
Query Neighborhood Hits	671	Target Neighborhood Hits	759	Shared Neighborhood Hits	390
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

DLK_HUMAN
θ value	1.5773e-20 (rank : 117)	NC score	0.860421 (rank : 29)
Query Neighborhood Hits	671	Target Neighborhood Hits	401	Shared Neighborhood Hits	367
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

MEGF8_MOUSE
θ value	2.06002e-20 (rank : 118)	NC score	0.773214 (rank : 78)
Query Neighborhood Hits	671	Target Neighborhood Hits	520	Shared Neighborhood Hits	372
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NID2_HUMAN
θ value	2.69047e-20 (rank : 119)	NC score	0.750008 (rank : 83)
Query Neighborhood Hits	671	Target Neighborhood Hits	456	Shared Neighborhood Hits	304
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	4.58923e-20 (rank : 120)	NC score	0.741095 (rank : 86)
Query Neighborhood Hits	671	Target Neighborhood Hits	338	Shared Neighborhood Hits	287
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

CD248_HUMAN
θ value	5.99374e-20 (rank : 121)	NC score	0.659058 (rank : 126)
Query Neighborhood Hits	671	Target Neighborhood Hits	679	Shared Neighborhood Hits	253
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

WIF1_MOUSE
θ value	1.02238e-19 (rank : 122)	NC score	0.803200 (rank : 70)
Query Neighborhood Hits	671	Target Neighborhood Hits	393	Shared Neighborhood Hits	367
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LRP8_HUMAN
θ value	2.27762e-19 (rank : 123)	NC score	0.606808 (rank : 157)
Query Neighborhood Hits	671	Target Neighborhood Hits	346	Shared Neighborhood Hits	273
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP4_MOUSE
θ value	2.97466e-19 (rank : 124)	NC score	0.589426 (rank : 166)
Query Neighborhood Hits	671	Target Neighborhood Hits	351	Shared Neighborhood Hits	285
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

SLIT3_HUMAN
θ value	2.97466e-19 (rank : 125)	NC score	0.573173 (rank : 174)
Query Neighborhood Hits	671	Target Neighborhood Hits	682	Shared Neighborhood Hits	357
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

LDLR_HUMAN
θ value	5.07402e-19 (rank : 126)	NC score	0.643986 (rank : 132)
Query Neighborhood Hits	671	Target Neighborhood Hits	375	Shared Neighborhood Hits	318
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

SLIT3_MOUSE
θ value	5.07402e-19 (rank : 127)	NC score	0.582130 (rank : 173)
Query Neighborhood Hits	671	Target Neighborhood Hits	700	Shared Neighborhood Hits	369
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

DLK_MOUSE
θ value	8.65492e-19 (rank : 128)	NC score	0.852148 (rank : 37)
Query Neighborhood Hits	671	Target Neighborhood Hits	374	Shared Neighborhood Hits	349
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

MEGF9_HUMAN
θ value	1.13037e-18 (rank : 129)	NC score	0.713180 (rank : 99)
Query Neighborhood Hits	671	Target Neighborhood Hits	557	Shared Neighborhood Hits	318
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CD248_MOUSE
θ value	1.47631e-18 (rank : 130)	NC score	0.667027 (rank : 118)
Query Neighborhood Hits	671	Target Neighborhood Hits	578	Shared Neighborhood Hits	237
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MEGF8_HUMAN
θ value	1.47631e-18 (rank : 131)	NC score	0.780789 (rank : 77)
Query Neighborhood Hits	671	Target Neighborhood Hits	528	Shared Neighborhood Hits	380
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LRP4_HUMAN
θ value	3.28887e-18 (rank : 132)	NC score	0.584817 (rank : 169)
Query Neighborhood Hits	671	Target Neighborhood Hits	355	Shared Neighborhood Hits	291
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

CELR3_MOUSE
θ value	4.29542e-18 (rank : 133)	NC score	0.402068 (rank : 246)
Query Neighborhood Hits	671	Target Neighborhood Hits	687	Shared Neighborhood Hits	349
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

LDLR_MOUSE
θ value	4.29542e-18 (rank : 134)	NC score	0.619757 (rank : 150)
Query Neighborhood Hits	671	Target Neighborhood Hits	382	Shared Neighborhood Hits	310
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

WIF1_HUMAN
θ value	4.29542e-18 (rank : 135)	NC score	0.803294 (rank : 69)
Query Neighborhood Hits	671	Target Neighborhood Hits	392	Shared Neighborhood Hits	363
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CELR3_HUMAN
θ value	5.60996e-18 (rank : 136)	NC score	0.404642 (rank : 245)
Query Neighborhood Hits	671	Target Neighborhood Hits	680	Shared Neighborhood Hits	343
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

SLIT1_HUMAN
θ value	5.60996e-18 (rank : 137)	NC score	0.611711 (rank : 154)
Query Neighborhood Hits	671	Target Neighborhood Hits	700	Shared Neighborhood Hits	375
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

VLDLR_HUMAN
θ value	5.60996e-18 (rank : 138)	NC score	0.633750 (rank : 138)
Query Neighborhood Hits	671	Target Neighborhood Hits	383	Shared Neighborhood Hits	308
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	7.32683e-18 (rank : 139)	NC score	0.631884 (rank : 141)
Query Neighborhood Hits	671	Target Neighborhood Hits	360	Shared Neighborhood Hits	296
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LRP8_MOUSE
θ value	9.56915e-18 (rank : 140)	NC score	0.628324 (rank : 144)
Query Neighborhood Hits	671	Target Neighborhood Hits	385	Shared Neighborhood Hits	303
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LAMC2_HUMAN
θ value	1.63225e-17 (rank : 141)	NC score	0.614134 (rank : 152)
Query Neighborhood Hits	671	Target Neighborhood Hits	715	Shared Neighborhood Hits	315
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

NID1_HUMAN
θ value	1.63225e-17 (rank : 142)	NC score	0.735894 (rank : 89)
Query Neighborhood Hits	671	Target Neighborhood Hits	329	Shared Neighborhood Hits	289
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

CD97_MOUSE
θ value	2.7842e-17 (rank : 143)	NC score	0.560500 (rank : 185)
Query Neighborhood Hits	671	Target Neighborhood Hits	295	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

MEGF9_MOUSE
θ value	3.63628e-17 (rank : 144)	NC score	0.672170 (rank : 116)
Query Neighborhood Hits	671	Target Neighborhood Hits	896	Shared Neighborhood Hits	300
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NAGPA_HUMAN
θ value	4.74913e-17 (rank : 145)	NC score	0.661030 (rank : 121)
Query Neighborhood Hits	671	Target Neighborhood Hits	282	Shared Neighborhood Hits	264
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

SLIT1_MOUSE
θ value	4.74913e-17 (rank : 146)	NC score	0.613379 (rank : 153)
Query Neighborhood Hits	671	Target Neighborhood Hits	715	Shared Neighborhood Hits	385
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

LRP1B_MOUSE
θ value	8.10077e-17 (rank : 147)	NC score	0.709263 (rank : 103)
Query Neighborhood Hits	671	Target Neighborhood Hits	606	Shared Neighborhood Hits	448
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

NAGPA_MOUSE
θ value	8.10077e-17 (rank : 148)	NC score	0.659688 (rank : 123)
Query Neighborhood Hits	671	Target Neighborhood Hits	308	Shared Neighborhood Hits	288
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LAMC2_MOUSE
θ value	1.058e-16 (rank : 149)	NC score	0.646077 (rank : 130)
Query Neighborhood Hits	671	Target Neighborhood Hits	614	Shared Neighborhood Hits	327
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

NID1_MOUSE
θ value	1.38178e-16 (rank : 150)	NC score	0.736382 (rank : 88)
Query Neighborhood Hits	671	Target Neighborhood Hits	335	Shared Neighborhood Hits	280
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

LRP1B_HUMAN
θ value	4.02038e-16 (rank : 151)	NC score	0.711074 (rank : 101)
Query Neighborhood Hits	671	Target Neighborhood Hits	602	Shared Neighborhood Hits	450
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TENR_HUMAN
θ value	4.02038e-16 (rank : 152)	NC score	0.472925 (rank : 223)
Query Neighborhood Hits	671	Target Neighborhood Hits	526	Shared Neighborhood Hits	322
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

SLIT2_HUMAN
θ value	5.25075e-16 (rank : 153)	NC score	0.595369 (rank : 165)
Query Neighborhood Hits	671	Target Neighborhood Hits	708	Shared Neighborhood Hits	379
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TENR_MOUSE
θ value	6.85773e-16 (rank : 154)	NC score	0.480785 (rank : 221)
Query Neighborhood Hits	671	Target Neighborhood Hits	531	Shared Neighborhood Hits	323
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

SSPO_MOUSE
θ value	8.95645e-16 (rank : 155)	NC score	0.491507 (rank : 213)
Query Neighborhood Hits	671	Target Neighborhood Hits	800	Shared Neighborhood Hits	445
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

LRP2_HUMAN
θ value	1.16975e-15 (rank : 156)	NC score	0.661378 (rank : 120)
Query Neighborhood Hits	671	Target Neighborhood Hits	573	Shared Neighborhood Hits	444
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

PGBM_HUMAN
θ value	1.16975e-15 (rank : 157)	NC score	0.490666 (rank : 214)
Query Neighborhood Hits	671	Target Neighborhood Hits	1113	Shared Neighborhood Hits	411
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

UROM_HUMAN
θ value	1.16975e-15 (rank : 158)	NC score	0.731124 (rank : 91)
Query Neighborhood Hits	671	Target Neighborhood Hits	284	Shared Neighborhood Hits	260
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

LRP1_HUMAN
θ value	1.99529e-15 (rank : 159)	NC score	0.720214 (rank : 93)
Query Neighborhood Hits	671	Target Neighborhood Hits	617	Shared Neighborhood Hits	461
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

SLIT2_MOUSE
θ value	1.99529e-15 (rank : 160)	NC score	0.587911 (rank : 168)
Query Neighborhood Hits	671	Target Neighborhood Hits	684	Shared Neighborhood Hits	358
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CELR2_HUMAN
θ value	2.60593e-15 (rank : 161)	NC score	0.410471 (rank : 243)
Query Neighborhood Hits	671	Target Neighborhood Hits	657	Shared Neighborhood Hits	368
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

KRA53_HUMAN
θ value	3.40345e-15 (rank : 162)	NC score	0.714814 (rank : 96)
Query Neighborhood Hits	671	Target Neighborhood Hits	331	Shared Neighborhood Hits	272
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

PGBM_MOUSE
θ value	5.8054e-15 (rank : 163)	NC score	0.500283 (rank : 212)
Query Neighborhood Hits	671	Target Neighborhood Hits	1073	Shared Neighborhood Hits	416
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CELR1_MOUSE
θ value	7.58209e-15 (rank : 164)	NC score	0.394923 (rank : 256)
Query Neighborhood Hits	671	Target Neighborhood Hits	617	Shared Neighborhood Hits	318
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR1_HUMAN
θ value	1.29331e-14 (rank : 165)	NC score	0.392156 (rank : 258)
Query Neighborhood Hits	671	Target Neighborhood Hits	613	Shared Neighborhood Hits	313
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

LAMA4_MOUSE
θ value	1.68911e-14 (rank : 166)	NC score	0.533938 (rank : 196)
Query Neighborhood Hits	671	Target Neighborhood Hits	584	Shared Neighborhood Hits	229
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

GRN_HUMAN
θ value	8.38298e-14 (rank : 167)	NC score	0.582254 (rank : 172)
Query Neighborhood Hits	671	Target Neighborhood Hits	268	Shared Neighborhood Hits	233
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

LAMA4_HUMAN
θ value	2.43908e-13 (rank : 168)	NC score	0.502090 (rank : 208)
Query Neighborhood Hits	671	Target Neighborhood Hits	708	Shared Neighborhood Hits	224
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TENN_MOUSE
θ value	4.16044e-13 (rank : 169)	NC score	0.408759 (rank : 244)
Query Neighborhood Hits	671	Target Neighborhood Hits	484	Shared Neighborhood Hits	290
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CELR2_MOUSE
θ value	5.43371e-13 (rank : 170)	NC score	0.372261 (rank : 270)
Query Neighborhood Hits	671	Target Neighborhood Hits	584	Shared Neighborhood Hits	310
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

TLL1_MOUSE
θ value	5.43371e-13 (rank : 171)	NC score	0.340662 (rank : 285)
Query Neighborhood Hits	671	Target Neighborhood Hits	237	Shared Neighborhood Hits	178
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

BMP1_HUMAN
θ value	9.26847e-13 (rank : 172)	NC score	0.342105 (rank : 284)
Query Neighborhood Hits	671	Target Neighborhood Hits	233	Shared Neighborhood Hits	179
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	9.26847e-13 (rank : 173)	NC score	0.343921 (rank : 282)
Query Neighborhood Hits	671	Target Neighborhood Hits	236	Shared Neighborhood Hits	180
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

ITB4_HUMAN
θ value	2.0648e-12 (rank : 174)	NC score	0.481770 (rank : 219)
Query Neighborhood Hits	671	Target Neighborhood Hits	458	Shared Neighborhood Hits	274
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KRA51_HUMAN
θ value	2.0648e-12 (rank : 175)	NC score	0.714521 (rank : 97)
Query Neighborhood Hits	671	Target Neighborhood Hits	288	Shared Neighborhood Hits	225
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

TENN_HUMAN
θ value	2.0648e-12 (rank : 176)	NC score	0.395704 (rank : 254)
Query Neighborhood Hits	671	Target Neighborhood Hits	453	Shared Neighborhood Hits	281
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

GRN_MOUSE
θ value	3.52202e-12 (rank : 177)	NC score	0.584034 (rank : 170)
Query Neighborhood Hits	671	Target Neighborhood Hits	248	Shared Neighborhood Hits	231
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

ELTD1_MOUSE
θ value	4.59992e-12 (rank : 178)	NC score	0.544917 (rank : 190)
Query Neighborhood Hits	671	Target Neighborhood Hits	288	Shared Neighborhood Hits	213
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

TLL2_HUMAN
θ value	4.59992e-12 (rank : 179)	NC score	0.334081 (rank : 289)
Query Neighborhood Hits	671	Target Neighborhood Hits	241	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CREL1_MOUSE
θ value	1.74796e-11 (rank : 180)	NC score	0.795995 (rank : 74)
Query Neighborhood Hits	671	Target Neighborhood Hits	524	Shared Neighborhood Hits	318
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

UROM_MOUSE
θ value	3.89403e-11 (rank : 181)	NC score	0.716309 (rank : 95)
Query Neighborhood Hits	671	Target Neighborhood Hits	276	Shared Neighborhood Hits	255
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

EGFL8_MOUSE
θ value	5.08577e-11 (rank : 182)	NC score	0.707958 (rank : 104)
Query Neighborhood Hits	671	Target Neighborhood Hits	266	Shared Neighborhood Hits	260
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

KR106_HUMAN
θ value	8.67504e-11 (rank : 183)	NC score	0.627386 (rank : 145)
Query Neighborhood Hits	671	Target Neighborhood Hits	347	Shared Neighborhood Hits	281
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

SUSD1_HUMAN
θ value	8.67504e-11 (rank : 184)	NC score	0.711277 (rank : 100)
Query Neighborhood Hits	671	Target Neighborhood Hits	285	Shared Neighborhood Hits	225
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TLL2_MOUSE
θ value	8.67504e-11 (rank : 185)	NC score	0.329157 (rank : 295)
Query Neighborhood Hits	671	Target Neighborhood Hits	240	Shared Neighborhood Hits	178
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

NTNG2_HUMAN
θ value	1.133e-10 (rank : 186)	NC score	0.599503 (rank : 161)
Query Neighborhood Hits	671	Target Neighborhood Hits	276	Shared Neighborhood Hits	253
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

KR107_HUMAN
θ value	1.9326e-10 (rank : 187)	NC score	0.633703 (rank : 139)
Query Neighborhood Hits	671	Target Neighborhood Hits	330	Shared Neighborhood Hits	264
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

LAMA3_HUMAN
θ value	1.9326e-10 (rank : 188)	NC score	0.527148 (rank : 197)
Query Neighborhood Hits	671	Target Neighborhood Hits	760	Shared Neighborhood Hits	284
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

KRA54_HUMAN
θ value	2.52405e-10 (rank : 189)	NC score	0.617937 (rank : 151)
Query Neighborhood Hits	671	Target Neighborhood Hits	270	Shared Neighborhood Hits	211
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

TLL1_HUMAN
θ value	2.52405e-10 (rank : 190)	NC score	0.333224 (rank : 291)
Query Neighborhood Hits	671	Target Neighborhood Hits	236	Shared Neighborhood Hits	174
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

CREL1_HUMAN
θ value	3.29651e-10 (rank : 191)	NC score	0.807953 (rank : 66)
Query Neighborhood Hits	671	Target Neighborhood Hits	441	Shared Neighborhood Hits	303
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

ITB5_MOUSE
θ value	3.29651e-10 (rank : 192)	NC score	0.553233 (rank : 186)
Query Neighborhood Hits	671	Target Neighborhood Hits	329	Shared Neighborhood Hits	303
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

FATH_HUMAN
θ value	4.30538e-10 (rank : 193)	NC score	0.419561 (rank : 239)
Query Neighborhood Hits	671	Target Neighborhood Hits	570	Shared Neighborhood Hits	328
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

KR105_HUMAN
θ value	5.62301e-10 (rank : 194)	NC score	0.501918 (rank : 209)
Query Neighborhood Hits	671	Target Neighborhood Hits	271	Shared Neighborhood Hits	220
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

ITB2_HUMAN
θ value	7.34386e-10 (rank : 195)	NC score	0.500656 (rank : 211)
Query Neighborhood Hits	671	Target Neighborhood Hits	282	Shared Neighborhood Hits	255
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_MOUSE
θ value	7.34386e-10 (rank : 196)	NC score	0.514030 (rank : 203)
Query Neighborhood Hits	671	Target Neighborhood Hits	319	Shared Neighborhood Hits	289
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB5_HUMAN
θ value	7.34386e-10 (rank : 197)	NC score	0.536109 (rank : 195)
Query Neighborhood Hits	671	Target Neighborhood Hits	310	Shared Neighborhood Hits	283
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

EDIL3_MOUSE
θ value	9.59137e-10 (rank : 198)	NC score	0.598934 (rank : 162)
Query Neighborhood Hits	671	Target Neighborhood Hits	317	Shared Neighborhood Hits	277
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

ITB2_MOUSE
θ value	1.25267e-09 (rank : 199)	NC score	0.524837 (rank : 199)
Query Neighborhood Hits	671	Target Neighborhood Hits	326	Shared Neighborhood Hits	298
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

LYAM3_HUMAN
θ value	1.25267e-09 (rank : 200)	NC score	0.368822 (rank : 274)
Query Neighborhood Hits	671	Target Neighborhood Hits	378	Shared Neighborhood Hits	245
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

EGFL7_HUMAN
θ value	1.63604e-09 (rank : 201)	NC score	0.771782 (rank : 79)
Query Neighborhood Hits	671	Target Neighborhood Hits	325	Shared Neighborhood Hits	305
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

ITB3_HUMAN
θ value	2.13673e-09 (rank : 202)	NC score	0.536873 (rank : 193)
Query Neighborhood Hits	671	Target Neighborhood Hits	325	Shared Neighborhood Hits	297
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KR104_HUMAN
θ value	2.13673e-09 (rank : 203)	NC score	0.625878 (rank : 146)
Query Neighborhood Hits	671	Target Neighborhood Hits	313	Shared Neighborhood Hits	245
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

MFGM_MOUSE
θ value	2.13673e-09 (rank : 204)	NC score	0.399244 (rank : 249)
Query Neighborhood Hits	671	Target Neighborhood Hits	233	Shared Neighborhood Hits	199
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

ITB6_HUMAN
θ value	2.79066e-09 (rank : 205)	NC score	0.539634 (rank : 191)
Query Neighborhood Hits	671	Target Neighborhood Hits	318	Shared Neighborhood Hits	285
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_MOUSE
θ value	2.79066e-09 (rank : 206)	NC score	0.516859 (rank : 202)
Query Neighborhood Hits	671	Target Neighborhood Hits	277	Shared Neighborhood Hits	257
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

LYAM3_MOUSE
θ value	2.79066e-09 (rank : 207)	NC score	0.411544 (rank : 242)
Query Neighborhood Hits	671	Target Neighborhood Hits	390	Shared Neighborhood Hits	260
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

NET4_MOUSE
θ value	2.79066e-09 (rank : 208)	NC score	0.479076 (rank : 222)
Query Neighborhood Hits	671	Target Neighborhood Hits	180	Shared Neighborhood Hits	165
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

ITB7_HUMAN
θ value	3.64472e-09 (rank : 209)	NC score	0.522040 (rank : 201)
Query Neighborhood Hits	671	Target Neighborhood Hits	290	Shared Neighborhood Hits	267
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

KRA55_HUMAN
θ value	3.64472e-09 (rank : 210)	NC score	0.621215 (rank : 147)
Query Neighborhood Hits	671	Target Neighborhood Hits	257	Shared Neighborhood Hits	203
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

PROC_MOUSE
θ value	3.64472e-09 (rank : 211)	NC score	0.319736 (rank : 302)
Query Neighborhood Hits	671	Target Neighborhood Hits	426	Shared Neighborhood Hits	272
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

EGFL8_HUMAN
θ value	4.76016e-09 (rank : 212)	NC score	0.710658 (rank : 102)
Query Neighborhood Hits	671	Target Neighborhood Hits	270	Shared Neighborhood Hits	256
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

NTNG1_HUMAN
θ value	4.76016e-09 (rank : 213)	NC score	0.571021 (rank : 176)
Query Neighborhood Hits	671	Target Neighborhood Hits	247	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PROZ_HUMAN
θ value	4.76016e-09 (rank : 214)	NC score	0.561309 (rank : 184)
Query Neighborhood Hits	671	Target Neighborhood Hits	422	Shared Neighborhood Hits	270
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

NET4_HUMAN
θ value	6.21693e-09 (rank : 215)	NC score	0.483819 (rank : 217)
Query Neighborhood Hits	671	Target Neighborhood Hits	191	Shared Neighborhood Hits	167
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NTNG2_MOUSE
θ value	8.11959e-09 (rank : 216)	NC score	0.607045 (rank : 156)
Query Neighborhood Hits	671	Target Neighborhood Hits	276	Shared Neighborhood Hits	260
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ITB6_MOUSE
θ value	1.06045e-08 (rank : 217)	NC score	0.562775 (rank : 183)
Query Neighborhood Hits	671	Target Neighborhood Hits	341	Shared Neighborhood Hits	297
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

TSP1_HUMAN
θ value	1.06045e-08 (rank : 218)	NC score	0.481179 (rank : 220)
Query Neighborhood Hits	671	Target Neighborhood Hits	389	Shared Neighborhood Hits	283
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

MASP2_HUMAN
θ value	1.38499e-08 (rank : 219)	NC score	0.188868 (rank : 399)
Query Neighborhood Hits	671	Target Neighborhood Hits	364	Shared Neighborhood Hits	156
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

FA9_HUMAN
θ value	1.80886e-08 (rank : 220)	NC score	0.307910 (rank : 311)
Query Neighborhood Hits	671	Target Neighborhood Hits	421	Shared Neighborhood Hits	257
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

PROC_HUMAN
θ value	1.80886e-08 (rank : 221)	NC score	0.289010 (rank : 322)
Query Neighborhood Hits	671	Target Neighborhood Hits	406	Shared Neighborhood Hits	254
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

TSP1_MOUSE
θ value	1.80886e-08 (rank : 222)	NC score	0.484407 (rank : 216)
Query Neighborhood Hits	671	Target Neighborhood Hits	396	Shared Neighborhood Hits	291
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

EGFL7_MOUSE
θ value	2.36244e-08 (rank : 223)	NC score	0.736508 (rank : 87)
Query Neighborhood Hits	671	Target Neighborhood Hits	287	Shared Neighborhood Hits	278
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

ITB8_HUMAN
θ value	3.08544e-08 (rank : 224)	NC score	0.436613 (rank : 234)
Query Neighborhood Hits	671	Target Neighborhood Hits	280	Shared Neighborhood Hits	249
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KRA52_HUMAN
θ value	3.08544e-08 (rank : 225)	NC score	0.563216 (rank : 182)
Query Neighborhood Hits	671	Target Neighborhood Hits	236	Shared Neighborhood Hits	196
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

COMP_MOUSE
θ value	6.87365e-08 (rank : 226)	NC score	0.644185 (rank : 131)
Query Neighborhood Hits	671	Target Neighborhood Hits	290	Shared Neighborhood Hits	260
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

HHIP_HUMAN
θ value	6.87365e-08 (rank : 227)	NC score	0.571266 (rank : 175)
Query Neighborhood Hits	671	Target Neighborhood Hits	249	Shared Neighborhood Hits	236
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KRA59_HUMAN
θ value	6.87365e-08 (rank : 228)	NC score	0.641072 (rank : 134)
Query Neighborhood Hits	671	Target Neighborhood Hits	310	Shared Neighborhood Hits	236
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

HABP2_HUMAN
θ value	8.97725e-08 (rank : 229)	NC score	0.338534 (rank : 286)
Query Neighborhood Hits	671	Target Neighborhood Hits	431	Shared Neighborhood Hits	262
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

KRA57_HUMAN
θ value	8.97725e-08 (rank : 230)	NC score	0.631248 (rank : 142)
Query Neighborhood Hits	671	Target Neighborhood Hits	269	Shared Neighborhood Hits	222
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	8.97725e-08 (rank : 231)	NC score	0.676581 (rank : 114)
Query Neighborhood Hits	671	Target Neighborhood Hits	324	Shared Neighborhood Hits	260
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

NTNG1_MOUSE
θ value	8.97725e-08 (rank : 232)	NC score	0.570295 (rank : 178)
Query Neighborhood Hits	671	Target Neighborhood Hits	246	Shared Neighborhood Hits	224
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

EDIL3_HUMAN
θ value	1.17247e-07 (rank : 233)	NC score	0.583317 (rank : 171)
Query Neighborhood Hits	671	Target Neighborhood Hits	292	Shared Neighborhood Hits	253
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

PROZ_MOUSE
θ value	1.17247e-07 (rank : 234)	NC score	0.570495 (rank : 177)
Query Neighborhood Hits	671	Target Neighborhood Hits	410	Shared Neighborhood Hits	263
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

TSP4_HUMAN
θ value	1.17247e-07 (rank : 235)	NC score	0.646780 (rank : 129)
Query Neighborhood Hits	671	Target Neighborhood Hits	277	Shared Neighborhood Hits	253
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

ESM1_MOUSE
θ value	1.53129e-07 (rank : 236)	NC score	0.252158 (rank : 339)
Query Neighborhood Hits	671	Target Neighborhood Hits	107	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

MASP2_MOUSE
θ value	1.53129e-07 (rank : 237)	NC score	0.184714 (rank : 403)
Query Neighborhood Hits	671	Target Neighborhood Hits	382	Shared Neighborhood Hits	162
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

TSP3_HUMAN
θ value	1.53129e-07 (rank : 238)	NC score	0.589072 (rank : 167)
Query Neighborhood Hits	671	Target Neighborhood Hits	250	Shared Neighborhood Hits	217
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

COMP_HUMAN
θ value	1.99992e-07 (rank : 239)	NC score	0.620220 (rank : 149)
Query Neighborhood Hits	671	Target Neighborhood Hits	258	Shared Neighborhood Hits	238
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

FA10_MOUSE
θ value	1.99992e-07 (rank : 240)	NC score	0.327868 (rank : 296)
Query Neighborhood Hits	671	Target Neighborhood Hits	435	Shared Neighborhood Hits	271
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

HGFA_MOUSE
θ value	1.99992e-07 (rank : 241)	NC score	0.258913 (rank : 332)
Query Neighborhood Hits	671	Target Neighborhood Hits	419	Shared Neighborhood Hits	238
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TSP3_MOUSE
θ value	1.99992e-07 (rank : 242)	NC score	0.596152 (rank : 164)
Query Neighborhood Hits	671	Target Neighborhood Hits	247	Shared Neighborhood Hits	221
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_MOUSE
θ value	1.99992e-07 (rank : 243)	NC score	0.654830 (rank : 127)
Query Neighborhood Hits	671	Target Neighborhood Hits	276	Shared Neighborhood Hits	255
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

CSPG3_MOUSE
θ value	2.61198e-07 (rank : 244)	NC score	0.461902 (rank : 229)
Query Neighborhood Hits	671	Target Neighborhood Hits	657	Shared Neighborhood Hits	273
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LYAM2_HUMAN
θ value	2.61198e-07 (rank : 245)	NC score	0.375095 (rank : 267)
Query Neighborhood Hits	671	Target Neighborhood Hits	394	Shared Neighborhood Hits	258
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

PAPPA_HUMAN
θ value	2.61198e-07 (rank : 246)	NC score	0.139881 (rank : 491)
Query Neighborhood Hits	671	Target Neighborhood Hits	161	Shared Neighborhood Hits	86
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CRIM1_HUMAN
θ value	3.41135e-07 (rank : 247)	NC score	0.538340 (rank : 192)
Query Neighborhood Hits	671	Target Neighborhood Hits	362	Shared Neighborhood Hits	283
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KR101_HUMAN
θ value	3.41135e-07 (rank : 248)	NC score	0.536370 (rank : 194)
Query Neighborhood Hits	671	Target Neighborhood Hits	261	Shared Neighborhood Hits	211
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

ATRN_HUMAN
θ value	4.45536e-07 (rank : 249)	NC score	0.505731 (rank : 206)
Query Neighborhood Hits	671	Target Neighborhood Hits	525	Shared Neighborhood Hits	301
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ITB1_MOUSE
θ value	4.45536e-07 (rank : 250)	NC score	0.484746 (rank : 215)
Query Neighborhood Hits	671	Target Neighborhood Hits	283	Shared Neighborhood Hits	250
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

HGFA_HUMAN
θ value	5.81887e-07 (rank : 251)	NC score	0.261767 (rank : 329)
Query Neighborhood Hits	671	Target Neighborhood Hits	436	Shared Neighborhood Hits	234
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

VWF_MOUSE
θ value	5.81887e-07 (rank : 252)	NC score	0.342544 (rank : 283)
Query Neighborhood Hits	671	Target Neighborhood Hits	381	Shared Neighborhood Hits	268
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FA10_HUMAN
θ value	7.59969e-07 (rank : 253)	NC score	0.324987 (rank : 297)
Query Neighborhood Hits	671	Target Neighborhood Hits	431	Shared Neighborhood Hits	263
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA12_HUMAN
θ value	7.59969e-07 (rank : 254)	NC score	0.236368 (rank : 348)
Query Neighborhood Hits	671	Target Neighborhood Hits	425	Shared Neighborhood Hits	229
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

VWF_HUMAN
θ value	7.59969e-07 (rank : 255)	NC score	0.372935 (rank : 269)
Query Neighborhood Hits	671	Target Neighborhood Hits	396	Shared Neighborhood Hits	281
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KR511_HUMAN
θ value	9.92553e-07 (rank : 256)	NC score	0.564957 (rank : 181)
Query Neighborhood Hits	671	Target Neighborhood Hits	231	Shared Neighborhood Hits	181
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

PCSK6_HUMAN
θ value	9.92553e-07 (rank : 257)	NC score	0.269721 (rank : 328)
Query Neighborhood Hits	671	Target Neighborhood Hits	298	Shared Neighborhood Hits	189
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

HHIP_MOUSE
θ value	1.29631e-06 (rank : 258)	NC score	0.547601 (rank : 189)
Query Neighborhood Hits	671	Target Neighborhood Hits	219	Shared Neighborhood Hits	204
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB1_HUMAN
θ value	1.29631e-06 (rank : 259)	NC score	0.483495 (rank : 218)
Query Neighborhood Hits	671	Target Neighborhood Hits	298	Shared Neighborhood Hits	261
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

PERT_HUMAN
θ value	1.29631e-06 (rank : 260)	NC score	0.346129 (rank : 281)
Query Neighborhood Hits	671	Target Neighborhood Hits	221	Shared Neighborhood Hits	166
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

ADA15_MOUSE
θ value	1.69304e-06 (rank : 261)	NC score	0.210466 (rank : 372)
Query Neighborhood Hits	671	Target Neighborhood Hits	324	Shared Neighborhood Hits	224
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA33_HUMAN
θ value	1.69304e-06 (rank : 262)	NC score	0.182571 (rank : 409)
Query Neighborhood Hits	671	Target Neighborhood Hits	264	Shared Neighborhood Hits	184
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

KR510_HUMAN
θ value	1.69304e-06 (rank : 263)	NC score	0.526043 (rank : 198)
Query Neighborhood Hits	671	Target Neighborhood Hits	217	Shared Neighborhood Hits	169
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

PAPPA_MOUSE
θ value	1.69304e-06 (rank : 264)	NC score	0.140439 (rank : 490)
Query Neighborhood Hits	671	Target Neighborhood Hits	153	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

FAT2_HUMAN
θ value	2.21117e-06 (rank : 265)	NC score	0.249228 (rank : 340)
Query Neighborhood Hits	671	Target Neighborhood Hits	507	Shared Neighborhood Hits	230
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

CSPG2_MOUSE
θ value	2.88788e-06 (rank : 266)	NC score	0.470387 (rank : 224)
Query Neighborhood Hits	671	Target Neighborhood Hits	711	Shared Neighborhood Hits	271
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

FA7_HUMAN
θ value	2.88788e-06 (rank : 267)	NC score	0.289411 (rank : 321)
Query Neighborhood Hits	671	Target Neighborhood Hits	404	Shared Neighborhood Hits	242
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

KR10B_HUMAN
θ value	3.77169e-06 (rank : 268)	NC score	0.467164 (rank : 225)
Query Neighborhood Hits	671	Target Neighborhood Hits	269	Shared Neighborhood Hits	215
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

ADA11_MOUSE
θ value	4.92598e-06 (rank : 269)	NC score	0.218917 (rank : 365)
Query Neighborhood Hits	671	Target Neighborhood Hits	263	Shared Neighborhood Hits	214
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ASTN_MOUSE
θ value	4.92598e-06 (rank : 270)	NC score	0.229183 (rank : 352)
Query Neighborhood Hits	671	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATRN_MOUSE
θ value	4.92598e-06 (rank : 271)	NC score	0.507811 (rank : 204)
Query Neighborhood Hits	671	Target Neighborhood Hits	519	Shared Neighborhood Hits	302
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

MATN1_HUMAN
θ value	4.92598e-06 (rank : 272)	NC score	0.311727 (rank : 309)
Query Neighborhood Hits	671	Target Neighborhood Hits	191	Shared Neighborhood Hits	143
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	4.92598e-06 (rank : 273)	NC score	0.310725 (rank : 310)
Query Neighborhood Hits	671	Target Neighborhood Hits	186	Shared Neighborhood Hits	139
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

SORL_MOUSE
θ value	4.92598e-06 (rank : 274)	NC score	0.428051 (rank : 235)
Query Neighborhood Hits	671	Target Neighborhood Hits	439	Shared Neighborhood Hits	261
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LRP6_HUMAN
θ value	6.43352e-06 (rank : 275)	NC score	0.335193 (rank : 287)
Query Neighborhood Hits	671	Target Neighborhood Hits	235	Shared Neighborhood Hits	173
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	1.09739e-05 (rank : 276)	NC score	0.330900 (rank : 294)
Query Neighborhood Hits	671	Target Neighborhood Hits	232	Shared Neighborhood Hits	172
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

ADAM8_MOUSE
θ value	1.43324e-05 (rank : 277)	NC score	0.212344 (rank : 370)
Query Neighborhood Hits	671	Target Neighborhood Hits	326	Shared Neighborhood Hits	220
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

CSPG2_HUMAN
θ value	1.43324e-05 (rank : 278)	NC score	0.464941 (rank : 228)
Query Neighborhood Hits	671	Target Neighborhood Hits	681	Shared Neighborhood Hits	271
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG3_HUMAN
θ value	1.43324e-05 (rank : 279)	NC score	0.451087 (rank : 233)
Query Neighborhood Hits	671	Target Neighborhood Hits	676	Shared Neighborhood Hits	259
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MASP1_HUMAN
θ value	1.43324e-05 (rank : 280)	NC score	0.178375 (rank : 419)
Query Neighborhood Hits	671	Target Neighborhood Hits	369	Shared Neighborhood Hits	157
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	1.43324e-05 (rank : 281)	NC score	0.174924 (rank : 428)
Query Neighborhood Hits	671	Target Neighborhood Hits	364	Shared Neighborhood Hits	158
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

ZAN_HUMAN
θ value	1.43324e-05 (rank : 282)	NC score	0.378981 (rank : 264)
Query Neighborhood Hits	671	Target Neighborhood Hits	679	Shared Neighborhood Hits	322
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

C1RA_MOUSE
θ value	1.87187e-05 (rank : 283)	NC score	0.213714 (rank : 367)
Query Neighborhood Hits	671	Target Neighborhood Hits	379	Shared Neighborhood Hits	171
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	1.87187e-05 (rank : 284)	NC score	0.210622 (rank : 371)
Query Neighborhood Hits	671	Target Neighborhood Hits	380	Shared Neighborhood Hits	171
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	1.87187e-05 (rank : 285)	NC score	0.197401 (rank : 386)
Query Neighborhood Hits	671	Target Neighborhood Hits	364	Shared Neighborhood Hits	161
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

NFX1_HUMAN
θ value	1.87187e-05 (rank : 286)	NC score	0.394271 (rank : 257)
Query Neighborhood Hits	671	Target Neighborhood Hits	405	Shared Neighborhood Hits	200
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

ASTN_HUMAN
θ value	2.44474e-05 (rank : 287)	NC score	0.231835 (rank : 350)
Query Neighborhood Hits	671	Target Neighborhood Hits	105	Shared Neighborhood Hits	84
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

FA7_MOUSE
θ value	2.44474e-05 (rank : 288)	NC score	0.243269 (rank : 342)
Query Neighborhood Hits	671	Target Neighborhood Hits	374	Shared Neighborhood Hits	215
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

HABP2_MOUSE
θ value	4.1701e-05 (rank : 289)	NC score	0.332484 (rank : 292)
Query Neighborhood Hits	671	Target Neighborhood Hits	445	Shared Neighborhood Hits	276
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

MUC5B_HUMAN
θ value	4.1701e-05 (rank : 290)	NC score	0.358880 (rank : 276)
Query Neighborhood Hits	671	Target Neighborhood Hits	1020	Shared Neighborhood Hits	319
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

ADA11_HUMAN
θ value	7.1131e-05 (rank : 291)	NC score	0.219273 (rank : 362)
Query Neighborhood Hits	671	Target Neighborhood Hits	259	Shared Neighborhood Hits	214
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA28_HUMAN
θ value	7.1131e-05 (rank : 292)	NC score	0.162659 (rank : 445)
Query Neighborhood Hits	671	Target Neighborhood Hits	244	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

KR102_HUMAN
θ value	7.1131e-05 (rank : 293)	NC score	0.505745 (rank : 205)
Query Neighborhood Hits	671	Target Neighborhood Hits	264	Shared Neighborhood Hits	214
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KRA56_HUMAN
θ value	7.1131e-05 (rank : 294)	NC score	0.552412 (rank : 187)
Query Neighborhood Hits	671	Target Neighborhood Hits	207	Shared Neighborhood Hits	173
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LRP5_MOUSE
θ value	7.1131e-05 (rank : 295)	NC score	0.320453 (rank : 301)
Query Neighborhood Hits	671	Target Neighborhood Hits	236	Shared Neighborhood Hits	168
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

SORL_HUMAN
θ value	7.1131e-05 (rank : 296)	NC score	0.415299 (rank : 241)
Query Neighborhood Hits	671	Target Neighborhood Hits	440	Shared Neighborhood Hits	251
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

ZNFX1_HUMAN
θ value	7.1131e-05 (rank : 297)	NC score	0.172481 (rank : 433)
Query Neighborhood Hits	671	Target Neighborhood Hits	308	Shared Neighborhood Hits	155
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

KR109_HUMAN
θ value	9.29e-05 (rank : 298)	NC score	0.458139 (rank : 230)
Query Neighborhood Hits	671	Target Neighborhood Hits	226	Shared Neighborhood Hits	184
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

LRP5_HUMAN
θ value	9.29e-05 (rank : 299)	NC score	0.314915 (rank : 308)
Query Neighborhood Hits	671	Target Neighborhood Hits	224	Shared Neighborhood Hits	161
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LYAM2_MOUSE
θ value	9.29e-05 (rank : 300)	NC score	0.384420 (rank : 261)
Query Neighborhood Hits	671	Target Neighborhood Hits	420	Shared Neighborhood Hits	281
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

PCSK5_HUMAN
θ value	9.29e-05 (rank : 301)	NC score	0.315535 (rank : 307)
Query Neighborhood Hits	671	Target Neighborhood Hits	291	Shared Neighborhood Hits	230
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

ADA33_MOUSE
θ value	0.000121331 (rank : 302)	NC score	0.176582 (rank : 422)
Query Neighborhood Hits	671	Target Neighborhood Hits	231	Shared Neighborhood Hits	183
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ELTD1_HUMAN
θ value	0.000121331 (rank : 303)	NC score	0.398911 (rank : 251)
Query Neighborhood Hits	671	Target Neighborhood Hits	269	Shared Neighborhood Hits	189
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ESM1_HUMAN
θ value	0.000121331 (rank : 304)	NC score	0.291849 (rank : 318)
Query Neighborhood Hits	671	Target Neighborhood Hits	110	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

NET2_MOUSE
θ value	0.000121331 (rank : 305)	NC score	0.466552 (rank : 226)
Query Neighborhood Hits	671	Target Neighborhood Hits	193	Shared Neighborhood Hits	167
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

KR10A_HUMAN
θ value	0.000158464 (rank : 306)	NC score	0.388331 (rank : 260)
Query Neighborhood Hits	671	Target Neighborhood Hits	232	Shared Neighborhood Hits	190
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

NET2_HUMAN
θ value	0.000158464 (rank : 307)	NC score	0.466171 (rank : 227)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	161
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

INSRR_MOUSE
θ value	0.00020696 (rank : 308)	NC score	0.073797 (rank : 668)
Query Neighborhood Hits	671	Target Neighborhood Hits	961	Shared Neighborhood Hits	156
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KR10C_HUMAN
θ value	0.00020696 (rank : 309)	NC score	0.455260 (rank : 232)
Query Neighborhood Hits	671	Target Neighborhood Hits	219	Shared Neighborhood Hits	182
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

TSP2_MOUSE
θ value	0.000270298 (rank : 310)	NC score	0.420296 (rank : 238)
Query Neighborhood Hits	671	Target Neighborhood Hits	352	Shared Neighborhood Hits	263
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ADAM8_HUMAN
θ value	0.00035302 (rank : 311)	NC score	0.210099 (rank : 373)
Query Neighborhood Hits	671	Target Neighborhood Hits	327	Shared Neighborhood Hits	232
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

INSRR_HUMAN
θ value	0.00035302 (rank : 312)	NC score	0.072080 (rank : 678)
Query Neighborhood Hits	671	Target Neighborhood Hits	950	Shared Neighborhood Hits	143
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

KR108_HUMAN
θ value	0.00035302 (rank : 313)	NC score	0.456345 (rank : 231)
Query Neighborhood Hits	671	Target Neighborhood Hits	226	Shared Neighborhood Hits	180
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

ADAM9_MOUSE
θ value	0.000461057 (rank : 314)	NC score	0.182003 (rank : 410)
Query Neighborhood Hits	671	Target Neighborhood Hits	325	Shared Neighborhood Hits	217
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADA15_HUMAN
θ value	0.000602161 (rank : 315)	NC score	0.196161 (rank : 388)
Query Neighborhood Hits	671	Target Neighborhood Hits	288	Shared Neighborhood Hits	214
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

TEFF2_MOUSE
θ value	0.000602161 (rank : 316)	NC score	0.304925 (rank : 313)
Query Neighborhood Hits	671	Target Neighborhood Hits	214	Shared Neighborhood Hits	155
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

KR103_HUMAN
θ value	0.000786445 (rank : 317)	NC score	0.372968 (rank : 268)
Query Neighborhood Hits	671	Target Neighborhood Hits	212	Shared Neighborhood Hits	178
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

TECTA_HUMAN
θ value	0.000786445 (rank : 318)	NC score	0.260796 (rank : 330)
Query Neighborhood Hits	671	Target Neighborhood Hits	239	Shared Neighborhood Hits	198
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

KRA92_HUMAN
θ value	0.00102713 (rank : 319)	NC score	0.381222 (rank : 262)
Query Neighborhood Hits	671	Target Neighborhood Hits	198	Shared Neighborhood Hits	160
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

PERT_MOUSE
θ value	0.00102713 (rank : 320)	NC score	0.319219 (rank : 303)
Query Neighborhood Hits	671	Target Neighborhood Hits	221	Shared Neighborhood Hits	160
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

TEFF2_HUMAN
θ value	0.00102713 (rank : 321)	NC score	0.301751 (rank : 314)
Query Neighborhood Hits	671	Target Neighborhood Hits	211	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

ADA28_MOUSE
θ value	0.00134147 (rank : 322)	NC score	0.158269 (rank : 455)
Query Neighborhood Hits	671	Target Neighborhood Hits	241	Shared Neighborhood Hits	191
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

CS1B_MOUSE
θ value	0.00134147 (rank : 323)	NC score	0.179747 (rank : 417)
Query Neighborhood Hits	671	Target Neighborhood Hits	361	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

KR171_HUMAN
θ value	0.00134147 (rank : 324)	NC score	0.549739 (rank : 188)
Query Neighborhood Hits	671	Target Neighborhood Hits	144	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LCE2B_HUMAN
θ value	0.00134147 (rank : 325)	NC score	0.192176 (rank : 395)
Query Neighborhood Hits	671	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

MUC2_HUMAN
θ value	0.00134147 (rank : 326)	NC score	0.223144 (rank : 360)
Query Neighborhood Hits	671	Target Neighborhood Hits	906	Shared Neighborhood Hits	198
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

WISP2_MOUSE
θ value	0.00134147 (rank : 327)	NC score	0.115098 (rank : 529)
Query Neighborhood Hits	671	Target Neighborhood Hits	129	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

CS1A_MOUSE
θ value	0.00175202 (rank : 328)	NC score	0.180987 (rank : 412)
Query Neighborhood Hits	671	Target Neighborhood Hits	360	Shared Neighborhood Hits	151
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

KRA13_HUMAN
θ value	0.00175202 (rank : 329)	NC score	0.401723 (rank : 247)
Query Neighborhood Hits	671	Target Neighborhood Hits	144	Shared Neighborhood Hits	119
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

LCE2C_HUMAN
θ value	0.00175202 (rank : 330)	NC score	0.219220 (rank : 363)
Query Neighborhood Hits	671	Target Neighborhood Hits	53	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

TDGF1_MOUSE
θ value	0.00175202 (rank : 331)	NC score	0.376470 (rank : 266)
Query Neighborhood Hits	671	Target Neighborhood Hits	146	Shared Neighborhood Hits	144
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TSP2_HUMAN
θ value	0.00175202 (rank : 332)	NC score	0.425301 (rank : 236)
Query Neighborhood Hits	671	Target Neighborhood Hits	359	Shared Neighborhood Hits	271
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

CYR61_HUMAN
θ value	0.00228821 (rank : 333)	NC score	0.127813 (rank : 510)
Query Neighborhood Hits	671	Target Neighborhood Hits	159	Shared Neighborhood Hits	106
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	0.00228821 (rank : 334)	NC score	0.128962 (rank : 509)
Query Neighborhood Hits	671	Target Neighborhood Hits	156	Shared Neighborhood Hits	102
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

ERBB3_HUMAN
θ value	0.00228821 (rank : 335)	NC score	0.056067 (rank : 767)
Query Neighborhood Hits	671	Target Neighborhood Hits	918	Shared Neighborhood Hits	132
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	0.00228821 (rank : 336)	NC score	0.050367 (rank : 822)
Query Neighborhood Hits	671	Target Neighborhood Hits	898	Shared Neighborhood Hits	111
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

EMR3_HUMAN
θ value	0.00298849 (rank : 337)	NC score	0.334560 (rank : 288)
Query Neighborhood Hits	671	Target Neighborhood Hits	245	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

NET1_HUMAN
θ value	0.00298849 (rank : 338)	NC score	0.421213 (rank : 237)
Query Neighborhood Hits	671	Target Neighborhood Hits	149	Shared Neighborhood Hits	127
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	0.00298849 (rank : 339)	NC score	0.417493 (rank : 240)
Query Neighborhood Hits	671	Target Neighborhood Hits	151	Shared Neighborhood Hits	126
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

TDGF2_HUMAN
θ value	0.00298849 (rank : 340)	NC score	0.318896 (rank : 304)
Query Neighborhood Hits	671	Target Neighborhood Hits	131	Shared Neighborhood Hits	127
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

ADA18_HUMAN
θ value	0.00390308 (rank : 341)	NC score	0.157824 (rank : 456)
Query Neighborhood Hits	671	Target Neighborhood Hits	184	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA22_HUMAN
θ value	0.00390308 (rank : 342)	NC score	0.158926 (rank : 451)
Query Neighborhood Hits	671	Target Neighborhood Hits	211	Shared Neighborhood Hits	165
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADAM9_HUMAN
θ value	0.00390308 (rank : 343)	NC score	0.170763 (rank : 434)
Query Neighborhood Hits	671	Target Neighborhood Hits	243	Shared Neighborhood Hits	198
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

EPHB4_HUMAN
θ value	0.00390308 (rank : 344)	NC score	0.076072 (rank : 655)
Query Neighborhood Hits	671	Target Neighborhood Hits	1056	Shared Neighborhood Hits	163
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

LCE2D_HUMAN
θ value	0.00390308 (rank : 345)	NC score	0.205919 (rank : 377)
Query Neighborhood Hits	671	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

TDGF1_HUMAN
θ value	0.00390308 (rank : 346)	NC score	0.322223 (rank : 300)
Query Neighborhood Hits	671	Target Neighborhood Hits	132	Shared Neighborhood Hits	131
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

C1S_HUMAN
θ value	0.00509761 (rank : 347)	NC score	0.175606 (rank : 426)
Query Neighborhood Hits	671	Target Neighborhood Hits	359	Shared Neighborhood Hits	157
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

RSPO4_HUMAN
θ value	0.00509761 (rank : 348)	NC score	0.153626 (rank : 461)
Query Neighborhood Hits	671	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SEM5A_HUMAN
θ value	0.00509761 (rank : 349)	NC score	0.055239 (rank : 775)
Query Neighborhood Hits	671	Target Neighborhood Hits	177	Shared Neighborhood Hits	71
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

CFC1_HUMAN
θ value	0.00665767 (rank : 350)	NC score	0.401536 (rank : 248)
Query Neighborhood Hits	671	Target Neighborhood Hits	148	Shared Neighborhood Hits	145
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

ERBB2_MOUSE
θ value	0.00665767 (rank : 351)	NC score	0.040029 (rank : 853)
Query Neighborhood Hits	671	Target Neighborhood Hits	918	Shared Neighborhood Hits	95
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

KR410_HUMAN
θ value	0.00665767 (rank : 352)	NC score	0.291224 (rank : 320)
Query Neighborhood Hits	671	Target Neighborhood Hits	156	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

LCE1B_HUMAN
θ value	0.00665767 (rank : 353)	NC score	0.377263 (rank : 265)
Query Neighborhood Hits	671	Target Neighborhood Hits	58	Shared Neighborhood Hits	52
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

PHXR5_MOUSE
θ value	0.00665767 (rank : 354)	NC score	0.286028 (rank : 324)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	77
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PROP_HUMAN
θ value	0.00665767 (rank : 355)	NC score	0.081776 (rank : 633)
Query Neighborhood Hits	671	Target Neighborhood Hits	126	Shared Neighborhood Hits	61
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

TECTA_MOUSE
θ value	0.00665767 (rank : 356)	NC score	0.280899 (rank : 326)
Query Neighborhood Hits	671	Target Neighborhood Hits	244	Shared Neighborhood Hits	207
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

DKK2_MOUSE
θ value	0.00869519 (rank : 357)	NC score	0.048493 (rank : 826)
Query Neighborhood Hits	671	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYZ8	Gene names	Dkk2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (mDkk-2).

KRA47_HUMAN
θ value	0.00869519 (rank : 358)	NC score	0.395116 (rank : 255)
Query Neighborhood Hits	671	Target Neighborhood Hits	204	Shared Neighborhood Hits	157
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

LYAM1_MOUSE
θ value	0.00869519 (rank : 359)	NC score	0.306624 (rank : 312)
Query Neighborhood Hits	671	Target Neighborhood Hits	332	Shared Neighborhood Hits	201
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

RSPO2_HUMAN
θ value	0.00869519 (rank : 360)	NC score	0.119218 (rank : 521)
Query Neighborhood Hits	671	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

ZNFX1_MOUSE
θ value	0.00869519 (rank : 361)	NC score	0.166544 (rank : 441)
Query Neighborhood Hits	671	Target Neighborhood Hits	407	Shared Neighborhood Hits	165
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CLC14_MOUSE
θ value	0.0113563 (rank : 362)	NC score	0.333608 (rank : 290)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	113
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

LCE1C_HUMAN
θ value	0.0113563 (rank : 363)	NC score	0.372159 (rank : 271)
Query Neighborhood Hits	671	Target Neighborhood Hits	65	Shared Neighborhood Hits	56
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1F_HUMAN
θ value	0.0113563 (rank : 364)	NC score	0.317141 (rank : 305)
Query Neighborhood Hits	671	Target Neighborhood Hits	48	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE5A_HUMAN
θ value	0.0113563 (rank : 365)	NC score	0.160698 (rank : 447)
Query Neighborhood Hits	671	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

RELN_HUMAN
θ value	0.0113563 (rank : 366)	NC score	0.245693 (rank : 341)
Query Neighborhood Hits	671	Target Neighborhood Hits	233	Shared Neighborhood Hits	188
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	0.0113563 (rank : 367)	NC score	0.254420 (rank : 336)
Query Neighborhood Hits	671	Target Neighborhood Hits	235	Shared Neighborhood Hits	191
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

TNR14_HUMAN
θ value	0.0113563 (rank : 368)	NC score	0.167973 (rank : 438)
Query Neighborhood Hits	671	Target Neighborhood Hits	149	Shared Neighborhood Hits	112
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ADA22_MOUSE
θ value	0.0148317 (rank : 369)	NC score	0.169846 (rank : 436)
Query Neighborhood Hits	671	Target Neighborhood Hits	225	Shared Neighborhood Hits	178
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

LCE1E_HUMAN
θ value	0.0148317 (rank : 370)	NC score	0.324370 (rank : 299)
Query Neighborhood Hits	671	Target Neighborhood Hits	53	Shared Neighborhood Hits	45
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

RSPO2_MOUSE
θ value	0.0148317 (rank : 371)	NC score	0.120777 (rank : 518)
Query Neighborhood Hits	671	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

TMPS6_MOUSE
θ value	0.0148317 (rank : 372)	NC score	0.131374 (rank : 507)
Query Neighborhood Hits	671	Target Neighborhood Hits	341	Shared Neighborhood Hits	149
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

WISP2_HUMAN
θ value	0.0148317 (rank : 373)	NC score	0.120082 (rank : 519)
Query Neighborhood Hits	671	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

INSR_HUMAN
θ value	0.0193708 (rank : 374)	NC score	0.055858 (rank : 769)
Query Neighborhood Hits	671	Target Neighborhood Hits	963	Shared Neighborhood Hits	139
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

KRA98_HUMAN
θ value	0.0193708 (rank : 375)	NC score	0.396064 (rank : 253)
Query Neighborhood Hits	671	Target Neighborhood Hits	185	Shared Neighborhood Hits	153
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	0.0193708 (rank : 376)	NC score	0.357952 (rank : 277)
Query Neighborhood Hits	671	Target Neighborhood Hits	173	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LORI_MOUSE
θ value	0.0193708 (rank : 377)	NC score	0.168252 (rank : 437)
Query Neighborhood Hits	671	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

TNR4_MOUSE
θ value	0.0193708 (rank : 378)	NC score	0.185649 (rank : 401)
Query Neighborhood Hits	671	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

CRAC1_MOUSE
θ value	0.0252991 (rank : 379)	NC score	0.354302 (rank : 279)
Query Neighborhood Hits	671	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

KRA11_HUMAN
θ value	0.0252991 (rank : 380)	NC score	0.380262 (rank : 263)
Query Neighborhood Hits	671	Target Neighborhood Hits	155	Shared Neighborhood Hits	131
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

RSPO4_MOUSE
θ value	0.0252991 (rank : 381)	NC score	0.141508 (rank : 488)
Query Neighborhood Hits	671	Target Neighborhood Hits	110	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SEM5A_MOUSE
θ value	0.0252991 (rank : 382)	NC score	0.041798 (rank : 845)
Query Neighborhood Hits	671	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATL3_HUMAN
θ value	0.0330416 (rank : 383)	NC score	0.043959 (rank : 840)
Query Neighborhood Hits	671	Target Neighborhood Hits	414	Shared Neighborhood Hits	86
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

CLC14_HUMAN
θ value	0.0330416 (rank : 384)	NC score	0.317028 (rank : 306)
Query Neighborhood Hits	671	Target Neighborhood Hits	143	Shared Neighborhood Hits	115
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CO8B_MOUSE
θ value	0.0330416 (rank : 385)	NC score	0.178871 (rank : 418)
Query Neighborhood Hits	671	Target Neighborhood Hits	224	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CRAC1_HUMAN
θ value	0.0330416 (rank : 386)	NC score	0.352963 (rank : 280)
Query Neighborhood Hits	671	Target Neighborhood Hits	111	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

PROP_MOUSE
θ value	0.0330416 (rank : 387)	NC score	0.092932 (rank : 594)
Query Neighborhood Hits	671	Target Neighborhood Hits	165	Shared Neighborhood Hits	73
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

VASN_HUMAN
θ value	0.0330416 (rank : 388)	NC score	0.137353 (rank : 496)
Query Neighborhood Hits	671	Target Neighborhood Hits	449	Shared Neighborhood Hits	138
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ADA12_MOUSE
θ value	0.0431538 (rank : 389)	NC score	0.139129 (rank : 494)
Query Neighborhood Hits	671	Target Neighborhood Hits	474	Shared Neighborhood Hits	146
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA19_HUMAN
θ value	0.0431538 (rank : 390)	NC score	0.183436 (rank : 406)
Query Neighborhood Hits	671	Target Neighborhood Hits	381	Shared Neighborhood Hits	190
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA25_MOUSE
θ value	0.0431538 (rank : 391)	NC score	0.146885 (rank : 475)
Query Neighborhood Hits	671	Target Neighborhood Hits	213	Shared Neighborhood Hits	167
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

CILP1_HUMAN
θ value	0.0431538 (rank : 392)	NC score	0.048301 (rank : 829)
Query Neighborhood Hits	671	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

KRA93_HUMAN
θ value	0.0431538 (rank : 393)	NC score	0.397120 (rank : 252)
Query Neighborhood Hits	671	Target Neighborhood Hits	203	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

UROK_MOUSE
θ value	0.0431538 (rank : 394)	NC score	0.094742 (rank : 585)
Query Neighborhood Hits	671	Target Neighborhood Hits	273	Shared Neighborhood Hits	124
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

CORIN_MOUSE
θ value	0.0563607 (rank : 395)	NC score	0.206425 (rank : 375)
Query Neighborhood Hits	671	Target Neighborhood Hits	451	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

KRA45_HUMAN
θ value	0.0563607 (rank : 396)	NC score	0.392089 (rank : 259)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	160
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

NRG2_HUMAN
θ value	0.0563607 (rank : 397)	NC score	0.156372 (rank : 457)
Query Neighborhood Hits	671	Target Neighborhood Hits	419	Shared Neighborhood Hits	114
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	0.0563607 (rank : 398)	NC score	0.185036 (rank : 402)
Query Neighborhood Hits	671	Target Neighborhood Hits	392	Shared Neighborhood Hits	128
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

ADAM7_HUMAN
θ value	0.0736092 (rank : 399)	NC score	0.167840 (rank : 439)
Query Neighborhood Hits	671	Target Neighborhood Hits	221	Shared Neighborhood Hits	183
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

DKK2_HUMAN
θ value	0.0736092 (rank : 400)	NC score	0.048232 (rank : 830)
Query Neighborhood Hits	671	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBU2, Q9UIU3	Gene names	DKK2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (hDkk-2).

EPHA1_HUMAN
θ value	0.0736092 (rank : 401)	NC score	0.052238 (rank : 803)
Query Neighborhood Hits	671	Target Neighborhood Hits	997	Shared Neighborhood Hits	131
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHB3_MOUSE
θ value	0.0736092 (rank : 402)	NC score	0.035778 (rank : 861)
Query Neighborhood Hits	671	Target Neighborhood Hits	996	Shared Neighborhood Hits	87
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

IGF1R_MOUSE
θ value	0.0736092 (rank : 403)	NC score	0.055392 (rank : 773)
Query Neighborhood Hits	671	Target Neighborhood Hits	973	Shared Neighborhood Hits	149
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

KRA15_HUMAN
θ value	0.0736092 (rank : 404)	NC score	0.331130 (rank : 293)
Query Neighborhood Hits	671	Target Neighborhood Hits	126	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

LYAM1_HUMAN
θ value	0.0736092 (rank : 405)	NC score	0.299479 (rank : 316)
Query Neighborhood Hits	671	Target Neighborhood Hits	315	Shared Neighborhood Hits	200
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

SPR2D_MOUSE
θ value	0.0736092 (rank : 406)	NC score	0.132538 (rank : 505)
Query Neighborhood Hits	671	Target Neighborhood Hits	61	Shared Neighborhood Hits	24
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2H_MOUSE
θ value	0.0736092 (rank : 407)	NC score	0.115588 (rank : 527)
Query Neighborhood Hits	671	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

THYG_HUMAN
θ value	0.0736092 (rank : 408)	NC score	0.070377 (rank : 683)
Query Neighborhood Hits	671	Target Neighborhood Hits	154	Shared Neighborhood Hits	79
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

VASN_MOUSE
θ value	0.0736092 (rank : 409)	NC score	0.127615 (rank : 511)
Query Neighborhood Hits	671	Target Neighborhood Hits	426	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

ADA19_MOUSE
θ value	0.0961366 (rank : 410)	NC score	0.189602 (rank : 398)
Query Neighborhood Hits	671	Target Neighborhood Hits	315	Shared Neighborhood Hits	209
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

CILP1_MOUSE
θ value	0.0961366 (rank : 411)	NC score	0.043005 (rank : 841)
Query Neighborhood Hits	671	Target Neighborhood Hits	282	Shared Neighborhood Hits	43
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

KR412_HUMAN
θ value	0.0961366 (rank : 412)	NC score	0.354932 (rank : 278)
Query Neighborhood Hits	671	Target Neighborhood Hits	178	Shared Neighborhood Hits	143
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA94_HUMAN
θ value	0.0961366 (rank : 413)	NC score	0.399068 (rank : 250)
Query Neighborhood Hits	671	Target Neighborhood Hits	204	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

MUC13_MOUSE
θ value	0.0961366 (rank : 414)	NC score	0.288356 (rank : 323)
Query Neighborhood Hits	671	Target Neighborhood Hits	447	Shared Neighborhood Hits	173
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

ADA10_MOUSE
θ value	0.125558 (rank : 415)	NC score	0.176461 (rank : 423)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	149
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA32_MOUSE
θ value	0.125558 (rank : 416)	NC score	0.145340 (rank : 481)
Query Neighborhood Hits	671	Target Neighborhood Hits	219	Shared Neighborhood Hits	178
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ATS20_MOUSE
θ value	0.125558 (rank : 417)	NC score	0.069773 (rank : 685)
Query Neighborhood Hits	671	Target Neighborhood Hits	225	Shared Neighborhood Hits	129
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

LCE3A_HUMAN
θ value	0.125558 (rank : 418)	NC score	0.291484 (rank : 319)
Query Neighborhood Hits	671	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

MT1E_HUMAN
θ value	0.125558 (rank : 419)	NC score	0.114948 (rank : 531)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	71
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT3_HUMAN
θ value	0.125558 (rank : 420)	NC score	0.238112 (rank : 347)
Query Neighborhood Hits	671	Target Neighborhood Hits	82	Shared Neighborhood Hits	73
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

NOV_MOUSE
θ value	0.125558 (rank : 421)	NC score	0.093606 (rank : 593)
Query Neighborhood Hits	671	Target Neighborhood Hits	130	Shared Neighborhood Hits	85
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

TNR21_HUMAN
θ value	0.125558 (rank : 422)	NC score	0.070139 (rank : 684)
Query Neighborhood Hits	671	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR25_HUMAN
θ value	0.125558 (rank : 423)	NC score	0.218970 (rank : 364)
Query Neighborhood Hits	671	Target Neighborhood Hits	172	Shared Neighborhood Hits	104
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

ADA12_HUMAN
θ value	0.163984 (rank : 424)	NC score	0.158853 (rank : 453)
Query Neighborhood Hits	671	Target Neighborhood Hits	224	Shared Neighborhood Hits	159
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

BMPER_HUMAN
θ value	0.163984 (rank : 425)	NC score	0.238665 (rank : 346)
Query Neighborhood Hits	671	Target Neighborhood Hits	175	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CTGF_HUMAN
θ value	0.163984 (rank : 426)	NC score	0.113684 (rank : 534)
Query Neighborhood Hits	671	Target Neighborhood Hits	128	Shared Neighborhood Hits	88
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

EGFR_HUMAN
θ value	0.163984 (rank : 427)	NC score	0.045392 (rank : 836)
Query Neighborhood Hits	671	Target Neighborhood Hits	939	Shared Neighborhood Hits	132
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EPHB6_MOUSE
θ value	0.163984 (rank : 428)	NC score	0.048350 (rank : 828)
Query Neighborhood Hits	671	Target Neighborhood Hits	906	Shared Neighborhood Hits	95
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

ERBB2_HUMAN
θ value	0.163984 (rank : 429)	NC score	0.041428 (rank : 846)
Query Neighborhood Hits	671	Target Neighborhood Hits	1073	Shared Neighborhood Hits	107
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

KRA24_HUMAN
θ value	0.163984 (rank : 430)	NC score	0.235018 (rank : 349)
Query Neighborhood Hits	671	Target Neighborhood Hits	192	Shared Neighborhood Hits	150
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

PGCA_HUMAN
θ value	0.163984 (rank : 431)	NC score	0.189697 (rank : 397)
Query Neighborhood Hits	671	Target Neighborhood Hits	821	Shared Neighborhood Hits	189
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

SPR2F_HUMAN
θ value	0.163984 (rank : 432)	NC score	0.114827 (rank : 532)
Query Neighborhood Hits	671	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

ST14_HUMAN
θ value	0.163984 (rank : 433)	NC score	0.193934 (rank : 391)
Query Neighborhood Hits	671	Target Neighborhood Hits	409	Shared Neighborhood Hits	202
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

TMPS6_HUMAN
θ value	0.163984 (rank : 434)	NC score	0.139814 (rank : 492)
Query Neighborhood Hits	671	Target Neighborhood Hits	338	Shared Neighborhood Hits	147
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TNR3_MOUSE
θ value	0.163984 (rank : 435)	NC score	0.109508 (rank : 544)
Query Neighborhood Hits	671	Target Neighborhood Hits	113	Shared Neighborhood Hits	76
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

ADA10_HUMAN
θ value	0.21417 (rank : 436)	NC score	0.183941 (rank : 404)
Query Neighborhood Hits	671	Target Neighborhood Hits	189	Shared Neighborhood Hits	151
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

EPHB4_MOUSE
θ value	0.21417 (rank : 437)	NC score	0.056456 (rank : 764)
Query Neighborhood Hits	671	Target Neighborhood Hits	1013	Shared Neighborhood Hits	135
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

IGF1R_HUMAN
θ value	0.21417 (rank : 438)	NC score	0.050282 (rank : 824)
Query Neighborhood Hits	671	Target Neighborhood Hits	977	Shared Neighborhood Hits	150
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IMPG1_HUMAN
θ value	0.21417 (rank : 439)	NC score	0.049679 (rank : 825)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	26
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

LCE2A_HUMAN
θ value	0.21417 (rank : 440)	NC score	0.205064 (rank : 379)
Query Neighborhood Hits	671	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

MT1A_HUMAN
θ value	0.21417 (rank : 441)	NC score	0.159880 (rank : 450)
Query Neighborhood Hits	671	Target Neighborhood Hits	74	Shared Neighborhood Hits	68
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1H_HUMAN
θ value	0.21417 (rank : 442)	NC score	0.133824 (rank : 504)
Query Neighborhood Hits	671	Target Neighborhood Hits	78	Shared Neighborhood Hits	71
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

RSPO3_HUMAN
θ value	0.21417 (rank : 443)	NC score	0.161957 (rank : 446)
Query Neighborhood Hits	671	Target Neighborhood Hits	128	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

TNR5_MOUSE
θ value	0.21417 (rank : 444)	NC score	0.126849 (rank : 512)
Query Neighborhood Hits	671	Target Neighborhood Hits	131	Shared Neighborhood Hits	98
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

ADA21_HUMAN
θ value	0.279714 (rank : 445)	NC score	0.139432 (rank : 493)
Query Neighborhood Hits	671	Target Neighborhood Hits	181	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

CFAI_HUMAN
θ value	0.279714 (rank : 446)	NC score	0.094655 (rank : 586)
Query Neighborhood Hits	671	Target Neighborhood Hits	289	Shared Neighborhood Hits	86
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CT127_HUMAN
θ value	0.279714 (rank : 447)	NC score	0.151985 (rank : 464)
Query Neighborhood Hits	671	Target Neighborhood Hits	67	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

EPHA1_MOUSE
θ value	0.279714 (rank : 448)	NC score	0.046876 (rank : 832)
Query Neighborhood Hits	671	Target Neighborhood Hits	958	Shared Neighborhood Hits	116
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHB1_HUMAN
θ value	0.279714 (rank : 449)	NC score	0.040011 (rank : 854)
Query Neighborhood Hits	671	Target Neighborhood Hits	988	Shared Neighborhood Hits	110
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

GP128_MOUSE
θ value	0.279714 (rank : 450)	NC score	0.111271 (rank : 538)
Query Neighborhood Hits	671	Target Neighborhood Hits	141	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

MFGM_HUMAN
θ value	0.279714 (rank : 451)	NC score	0.194248 (rank : 390)
Query Neighborhood Hits	671	Target Neighborhood Hits	150	Shared Neighborhood Hits	120
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MT1B_HUMAN
θ value	0.279714 (rank : 452)	NC score	0.151831 (rank : 465)
Query Neighborhood Hits	671	Target Neighborhood Hits	87	Shared Neighborhood Hits	80
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1L_HUMAN
θ value	0.279714 (rank : 453)	NC score	0.115149 (rank : 528)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	67
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT2_MOUSE
θ value	0.279714 (rank : 454)	NC score	0.148913 (rank : 468)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

RSPO3_MOUSE
θ value	0.279714 (rank : 455)	NC score	0.145695 (rank : 478)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

SPR2G_MOUSE
θ value	0.279714 (rank : 456)	NC score	0.116511 (rank : 524)
Query Neighborhood Hits	671	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

TNR16_HUMAN
θ value	0.279714 (rank : 457)	NC score	0.212832 (rank : 368)
Query Neighborhood Hits	671	Target Neighborhood Hits	183	Shared Neighborhood Hits	127
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR6B_HUMAN
θ value	0.279714 (rank : 458)	NC score	0.099726 (rank : 571)
Query Neighborhood Hits	671	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

ADA23_HUMAN
θ value	0.365318 (rank : 459)	NC score	0.197733 (rank : 385)
Query Neighborhood Hits	671	Target Neighborhood Hits	235	Shared Neighborhood Hits	192
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

BMPER_MOUSE
θ value	0.365318 (rank : 460)	NC score	0.258239 (rank : 333)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CFC1_MOUSE
θ value	0.365318 (rank : 461)	NC score	0.363491 (rank : 275)
Query Neighborhood Hits	671	Target Neighborhood Hits	125	Shared Neighborhood Hits	124
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CO6_HUMAN
θ value	0.365318 (rank : 462)	NC score	0.212803 (rank : 369)
Query Neighborhood Hits	671	Target Neighborhood Hits	331	Shared Neighborhood Hits	191
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CTGF_MOUSE
θ value	0.365318 (rank : 463)	NC score	0.108815 (rank : 545)
Query Neighborhood Hits	671	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

ENPP2_MOUSE
θ value	0.365318 (rank : 464)	NC score	0.040433 (rank : 849)
Query Neighborhood Hits	671	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

EREG_HUMAN
θ value	0.365318 (rank : 465)	NC score	0.148017 (rank : 471)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

KAZD1_HUMAN
θ value	0.365318 (rank : 466)	NC score	0.042131 (rank : 843)
Query Neighborhood Hits	671	Target Neighborhood Hits	248	Shared Neighborhood Hits	49
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

LCE1D_HUMAN
θ value	0.365318 (rank : 467)	NC score	0.324461 (rank : 298)
Query Neighborhood Hits	671	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

MCSP_MOUSE
θ value	0.365318 (rank : 468)	NC score	0.193783 (rank : 392)
Query Neighborhood Hits	671	Target Neighborhood Hits	108	Shared Neighborhood Hits	70
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

NRX2A_HUMAN
θ value	0.365318 (rank : 469)	NC score	0.229952 (rank : 351)
Query Neighborhood Hits	671	Target Neighborhood Hits	614	Shared Neighborhood Hits	146
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

TNR4_HUMAN
θ value	0.365318 (rank : 470)	NC score	0.165676 (rank : 442)
Query Neighborhood Hits	671	Target Neighborhood Hits	152	Shared Neighborhood Hits	96
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR6_MOUSE
θ value	0.365318 (rank : 471)	NC score	0.096110 (rank : 579)
Query Neighborhood Hits	671	Target Neighborhood Hits	99	Shared Neighborhood Hits	67
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

VEGFC_HUMAN
θ value	0.365318 (rank : 472)	NC score	0.179834 (rank : 416)
Query Neighborhood Hits	671	Target Neighborhood Hits	128	Shared Neighborhood Hits	107
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CAC1I_HUMAN
θ value	0.47712 (rank : 473)	NC score	0.000924 (rank : 921)
Query Neighborhood Hits	671	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CORIN_HUMAN
θ value	0.47712 (rank : 474)	NC score	0.226780 (rank : 355)
Query Neighborhood Hits	671	Target Neighborhood Hits	453	Shared Neighborhood Hits	233
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

EPHA8_MOUSE
θ value	0.47712 (rank : 475)	NC score	0.030668 (rank : 869)
Query Neighborhood Hits	671	Target Neighborhood Hits	969	Shared Neighborhood Hits	71
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

EPHB3_HUMAN
θ value	0.47712 (rank : 476)	NC score	0.038290 (rank : 855)
Query Neighborhood Hits	671	Target Neighborhood Hits	996	Shared Neighborhood Hits	91
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

TNR3_HUMAN
θ value	0.47712 (rank : 477)	NC score	0.100042 (rank : 569)
Query Neighborhood Hits	671	Target Neighborhood Hits	145	Shared Neighborhood Hits	73
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

WFDC3_HUMAN
θ value	0.47712 (rank : 478)	NC score	0.200183 (rank : 383)
Query Neighborhood Hits	671	Target Neighborhood Hits	138	Shared Neighborhood Hits	101
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ADA21_MOUSE
θ value	0.62314 (rank : 479)	NC score	0.145949 (rank : 477)
Query Neighborhood Hits	671	Target Neighborhood Hits	172	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

APR3_MOUSE
θ value	0.62314 (rank : 480)	NC score	0.160062 (rank : 449)
Query Neighborhood Hits	671	Target Neighborhood Hits	61	Shared Neighborhood Hits	58
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ATS1_HUMAN
θ value	0.62314 (rank : 481)	NC score	0.051631 (rank : 808)
Query Neighborhood Hits	671	Target Neighborhood Hits	159	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

BAI1_HUMAN
θ value	0.62314 (rank : 482)	NC score	0.109556 (rank : 543)
Query Neighborhood Hits	671	Target Neighborhood Hits	375	Shared Neighborhood Hits	84
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

COGA1_HUMAN
θ value	0.62314 (rank : 483)	NC score	0.022587 (rank : 885)
Query Neighborhood Hits	671	Target Neighborhood Hits	345	Shared Neighborhood Hits	35
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

EPHA7_MOUSE
θ value	0.62314 (rank : 484)	NC score	0.044376 (rank : 839)
Query Neighborhood Hits	671	Target Neighborhood Hits	1025	Shared Neighborhood Hits	121
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

KR211_HUMAN
θ value	0.62314 (rank : 485)	NC score	0.058168 (rank : 746)
Query Neighborhood Hits	671	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q3LI58	Gene names	KRTAP21-1, KAP21.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 21-1.

LCE1A_HUMAN
θ value	0.62314 (rank : 486)	NC score	0.293356 (rank : 317)
Query Neighborhood Hits	671	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

MKS3_MOUSE
θ value	0.62314 (rank : 487)	NC score	0.173586 (rank : 431)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

ADA30_HUMAN
θ value	0.813845 (rank : 488)	NC score	0.155782 (rank : 459)
Query Neighborhood Hits	671	Target Neighborhood Hits	391	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADAM2_MOUSE
θ value	0.813845 (rank : 489)	NC score	0.160218 (rank : 448)
Query Neighborhood Hits	671	Target Neighborhood Hits	209	Shared Neighborhood Hits	166
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

CNTP2_HUMAN
θ value	0.813845 (rank : 490)	NC score	0.221289 (rank : 361)
Query Neighborhood Hits	671	Target Neighborhood Hits	199	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	0.813845 (rank : 491)	NC score	0.223871 (rank : 359)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	139
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CO3A1_HUMAN
θ value	0.813845 (rank : 492)	NC score	0.021478 (rank : 887)
Query Neighborhood Hits	671	Target Neighborhood Hits	452	Shared Neighborhood Hits	45
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

ENPP2_HUMAN
θ value	0.813845 (rank : 493)	NC score	0.031965 (rank : 865)
Query Neighborhood Hits	671	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

EPHB6_HUMAN
θ value	0.813845 (rank : 494)	NC score	0.056512 (rank : 762)
Query Neighborhood Hits	671	Target Neighborhood Hits	912	Shared Neighborhood Hits	112
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

ERBB4_HUMAN
θ value	0.813845 (rank : 495)	NC score	0.048422 (rank : 827)
Query Neighborhood Hits	671	Target Neighborhood Hits	910	Shared Neighborhood Hits	111
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

HTRA1_MOUSE
θ value	0.813845 (rank : 496)	NC score	0.031939 (rank : 866)
Query Neighborhood Hits	671	Target Neighborhood Hits	140	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

KR221_HUMAN
θ value	0.813845 (rank : 497)	NC score	0.077706 (rank : 650)
Query Neighborhood Hits	671	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

MT1_MOUSE
θ value	0.813845 (rank : 498)	NC score	0.140735 (rank : 489)
Query Neighborhood Hits	671	Target Neighborhood Hits	72	Shared Neighborhood Hits	65
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

TNR11_HUMAN
θ value	0.813845 (rank : 499)	NC score	0.131872 (rank : 506)
Query Neighborhood Hits	671	Target Neighborhood Hits	135	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TPA_MOUSE
θ value	0.813845 (rank : 500)	NC score	0.148542 (rank : 470)
Query Neighborhood Hits	671	Target Neighborhood Hits	335	Shared Neighborhood Hits	179
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRI42_MOUSE
θ value	0.813845 (rank : 501)	NC score	0.052571 (rank : 801)
Query Neighborhood Hits	671	Target Neighborhood Hits	316	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

UROL1_HUMAN
θ value	0.813845 (rank : 502)	NC score	0.285497 (rank : 325)
Query Neighborhood Hits	671	Target Neighborhood Hits	213	Shared Neighborhood Hits	141
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ADA32_HUMAN
θ value	1.06291 (rank : 503)	NC score	0.154007 (rank : 460)
Query Neighborhood Hits	671	Target Neighborhood Hits	216	Shared Neighborhood Hits	175
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADAM7_MOUSE
θ value	1.06291 (rank : 504)	NC score	0.142606 (rank : 484)
Query Neighborhood Hits	671	Target Neighborhood Hits	200	Shared Neighborhood Hits	156
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

DKK1_HUMAN
θ value	1.06291 (rank : 505)	NC score	0.028551 (rank : 874)
Query Neighborhood Hits	671	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	O94907	Gene names	DKK1
Domain Architecture
Description	Dickkopf-related protein 1 precursor (Dkk-1) (Dickkopf-1) (hDkk-1) (SK).

MT4_MOUSE
θ value	1.06291 (rank : 506)	NC score	0.226489 (rank : 356)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	95
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

SO2A1_HUMAN
θ value	1.06291 (rank : 507)	NC score	0.007754 (rank : 910)
Query Neighborhood Hits	671	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SPR2I_MOUSE
θ value	1.06291 (rank : 508)	NC score	0.086705 (rank : 610)
Query Neighborhood Hits	671	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

TNR21_MOUSE
θ value	1.06291 (rank : 509)	NC score	0.072696 (rank : 675)
Query Neighborhood Hits	671	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

AD26A_MOUSE
θ value	1.38821 (rank : 510)	NC score	0.115735 (rank : 526)
Query Neighborhood Hits	671	Target Neighborhood Hits	165	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA17_MOUSE
θ value	1.38821 (rank : 511)	NC score	0.146930 (rank : 474)
Query Neighborhood Hits	671	Target Neighborhood Hits	201	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA18_MOUSE
θ value	1.38821 (rank : 512)	NC score	0.179957 (rank : 415)
Query Neighborhood Hits	671	Target Neighborhood Hits	227	Shared Neighborhood Hits	189
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADM1B_MOUSE
θ value	1.38821 (rank : 513)	NC score	0.146481 (rank : 476)
Query Neighborhood Hits	671	Target Neighborhood Hits	236	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

CECR6_HUMAN
θ value	1.38821 (rank : 514)	NC score	0.010890 (rank : 901)
Query Neighborhood Hits	671	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXQ6	Gene names	CECR6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6.

CO5A2_HUMAN
θ value	1.38821 (rank : 515)	NC score	0.029104 (rank : 873)
Query Neighborhood Hits	671	Target Neighborhood Hits	760	Shared Neighborhood Hits	78
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

CO8B_HUMAN
θ value	1.38821 (rank : 516)	NC score	0.138405 (rank : 495)
Query Neighborhood Hits	671	Target Neighborhood Hits	199	Shared Neighborhood Hits	108
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

EMR4_MOUSE
θ value	1.38821 (rank : 517)	NC score	0.242432 (rank : 344)
Query Neighborhood Hits	671	Target Neighborhood Hits	191	Shared Neighborhood Hits	121
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

EPHA2_HUMAN
θ value	1.38821 (rank : 518)	NC score	0.044864 (rank : 838)
Query Neighborhood Hits	671	Target Neighborhood Hits	1021	Shared Neighborhood Hits	107
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA7_HUMAN
θ value	1.38821 (rank : 519)	NC score	0.053548 (rank : 792)
Query Neighborhood Hits	671	Target Neighborhood Hits	1053	Shared Neighborhood Hits	148
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

MT2_HUMAN
θ value	1.38821 (rank : 520)	NC score	0.097404 (rank : 572)
Query Neighborhood Hits	671	Target Neighborhood Hits	69	Shared Neighborhood Hits	67
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MT3_MOUSE
θ value	1.38821 (rank : 521)	NC score	0.255871 (rank : 334)
Query Neighborhood Hits	671	Target Neighborhood Hits	68	Shared Neighborhood Hits	62
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MUC13_HUMAN
θ value	1.38821 (rank : 522)	NC score	0.185652 (rank : 400)
Query Neighborhood Hits	671	Target Neighborhood Hits	164	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

NOV_HUMAN
θ value	1.38821 (rank : 523)	NC score	0.102601 (rank : 563)
Query Neighborhood Hits	671	Target Neighborhood Hits	128	Shared Neighborhood Hits	89
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

PKHB2_HUMAN
θ value	1.38821 (rank : 524)	NC score	0.008858 (rank : 906)
Query Neighborhood Hits	671	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

SMDF_HUMAN
θ value	1.38821 (rank : 525)	NC score	0.183282 (rank : 407)
Query Neighborhood Hits	671	Target Neighborhood Hits	117	Shared Neighborhood Hits	83
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SYN2_HUMAN
θ value	1.38821 (rank : 526)	NC score	0.003043 (rank : 917)
Query Neighborhood Hits	671	Target Neighborhood Hits	213	Shared Neighborhood Hits	8
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

TR19L_MOUSE
θ value	1.38821 (rank : 527)	NC score	0.072258 (rank : 676)
Query Neighborhood Hits	671	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

WISP1_HUMAN
θ value	1.38821 (rank : 528)	NC score	0.084662 (rank : 623)
Query Neighborhood Hits	671	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

ADA17_HUMAN
θ value	1.81305 (rank : 529)	NC score	0.176456 (rank : 424)
Query Neighborhood Hits	671	Target Neighborhood Hits	223	Shared Neighborhood Hits	166
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA23_MOUSE
θ value	1.81305 (rank : 530)	NC score	0.193370 (rank : 394)
Query Neighborhood Hits	671	Target Neighborhood Hits	245	Shared Neighborhood Hits	207
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADM1A_MOUSE
θ value	1.81305 (rank : 531)	NC score	0.162985 (rank : 444)
Query Neighborhood Hits	671	Target Neighborhood Hits	230	Shared Neighborhood Hits	186
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ATL2_MOUSE
θ value	1.81305 (rank : 532)	NC score	0.045747 (rank : 835)
Query Neighborhood Hits	671	Target Neighborhood Hits	137	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

EPHAA_HUMAN
θ value	1.81305 (rank : 533)	NC score	0.046621 (rank : 833)
Query Neighborhood Hits	671	Target Neighborhood Hits	960	Shared Neighborhood Hits	94
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHB2_HUMAN
θ value	1.81305 (rank : 534)	NC score	0.040321 (rank : 851)
Query Neighborhood Hits	671	Target Neighborhood Hits	983	Shared Neighborhood Hits	100
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	1.81305 (rank : 535)	NC score	0.040355 (rank : 850)
Query Neighborhood Hits	671	Target Neighborhood Hits	982	Shared Neighborhood Hits	100
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

FBX38_MOUSE
θ value	1.81305 (rank : 536)	NC score	0.010874 (rank : 902)
Query Neighborhood Hits	671	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMI0, Q8BTQ4, Q8C0H4	Gene names	Fbxo38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity) (MoKA).

IBP6_MOUSE
θ value	1.81305 (rank : 537)	NC score	0.030003 (rank : 870)
Query Neighborhood Hits	671	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

MT1F_HUMAN
θ value	1.81305 (rank : 538)	NC score	0.103146 (rank : 560)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	68
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

NRX3A_HUMAN
θ value	1.81305 (rank : 539)	NC score	0.240126 (rank : 345)
Query Neighborhood Hits	671	Target Neighborhood Hits	164	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

SPR2E_MOUSE
θ value	1.81305 (rank : 540)	NC score	0.073382 (rank : 671)
Query Neighborhood Hits	671	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_MOUSE
θ value	1.81305 (rank : 541)	NC score	0.066513 (rank : 699)
Query Neighborhood Hits	671	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

TNR16_MOUSE
θ value	1.81305 (rank : 542)	NC score	0.204524 (rank : 380)
Query Neighborhood Hits	671	Target Neighborhood Hits	178	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TYRO_HUMAN
θ value	1.81305 (rank : 543)	NC score	0.034462 (rank : 864)
Query Neighborhood Hits	671	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P14679, Q15675, Q15676, Q15680, Q8TAK4, Q9BYY0, Q9BZX1	Gene names	TYR
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Tumor rejection antigen AB) (SK29-AB) (LB24-AB).

TYRP2_HUMAN
θ value	1.81305 (rank : 544)	NC score	0.037236 (rank : 857)
Query Neighborhood Hits	671	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	P40126	Gene names	DCT, TYRP2
Domain Architecture
Description	L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2).

ATL2_HUMAN
θ value	2.36792 (rank : 545)	NC score	0.050351 (rank : 823)
Query Neighborhood Hits	671	Target Neighborhood Hits	125	Shared Neighborhood Hits	62
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

AXUD1_MOUSE
θ value	2.36792 (rank : 546)	NC score	0.013219 (rank : 896)
Query Neighborhood Hits	671	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	P59054	Gene names	Axud1, Taip3
Domain Architecture	No domain graphic available
Description	Axin-1 up-regulated gene 1 protein (TGF-beta-induced apoptosis protein 3) (TAIP-3).

CN065_HUMAN
θ value	2.36792 (rank : 547)	NC score	0.014476 (rank : 893)
Query Neighborhood Hits	671	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N9R9	Gene names	C14orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf65.

DKK1_MOUSE
θ value	2.36792 (rank : 548)	NC score	0.031211 (rank : 868)
Query Neighborhood Hits	671	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	O54908	Gene names	Dkk1
Domain Architecture
Description	Dickkopf-related protein 1 precursor (Dkk-1) (Dickkopf-1) (mDkk-1).

GNPTA_HUMAN
θ value	2.36792 (rank : 549)	NC score	0.088521 (rank : 605)
Query Neighborhood Hits	671	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

IBP1_MOUSE
θ value	2.36792 (rank : 550)	NC score	0.029762 (rank : 871)
Query Neighborhood Hits	671	Target Neighborhood Hits	97	Shared Neighborhood Hits	45
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

MT1I_HUMAN
θ value	2.36792 (rank : 551)	NC score	0.087741 (rank : 607)
Query Neighborhood Hits	671	Target Neighborhood Hits	64	Shared Neighborhood Hits	60
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

MT1X_HUMAN
θ value	2.36792 (rank : 552)	NC score	0.156313 (rank : 458)
Query Neighborhood Hits	671	Target Neighborhood Hits	76	Shared Neighborhood Hits	73
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

NRG4_HUMAN
θ value	2.36792 (rank : 553)	NC score	0.180510 (rank : 413)
Query Neighborhood Hits	671	Target Neighborhood Hits	85	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

PGCB_MOUSE
θ value	2.36792 (rank : 554)	NC score	0.242687 (rank : 343)
Query Neighborhood Hits	671	Target Neighborhood Hits	459	Shared Neighborhood Hits	190
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

RSN_HUMAN
θ value	2.36792 (rank : 555)	NC score	0.013619 (rank : 895)
Query Neighborhood Hits	671	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HD89, Q540D9	Gene names	RETN, FIZZ3, HXCP1, RSTN
Domain Architecture
Description	Resistin precursor (Cysteine-rich secreted protein FIZZ3) (Adipose tissue-specific secretory factor) (ADSF) (C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein) (Cysteine-rich secreted protein A12-alpha-like 2).

TNR11_MOUSE
θ value	2.36792 (rank : 556)	NC score	0.109800 (rank : 542)
Query Neighborhood Hits	671	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR7_HUMAN
θ value	2.36792 (rank : 557)	NC score	0.148005 (rank : 472)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	97
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TPA_HUMAN
θ value	2.36792 (rank : 558)	NC score	0.147165 (rank : 473)
Query Neighborhood Hits	671	Target Neighborhood Hits	324	Shared Neighborhood Hits	170
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

UROK_HUMAN
θ value	2.36792 (rank : 559)	NC score	0.091531 (rank : 599)
Query Neighborhood Hits	671	Target Neighborhood Hits	272	Shared Neighborhood Hits	121
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROL1_MOUSE
θ value	2.36792 (rank : 560)	NC score	0.299911 (rank : 315)
Query Neighborhood Hits	671	Target Neighborhood Hits	235	Shared Neighborhood Hits	151
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

BTC_MOUSE
θ value	3.0926 (rank : 561)	NC score	0.113758 (rank : 533)
Query Neighborhood Hits	671	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

EGFR_MOUSE
θ value	3.0926 (rank : 562)	NC score	0.042637 (rank : 842)
Query Neighborhood Hits	671	Target Neighborhood Hits	927	Shared Neighborhood Hits	117
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

HHCM_HUMAN
θ value	3.0926 (rank : 563)	NC score	0.009939 (rank : 903)
Query Neighborhood Hits	671	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q05877	Gene names
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma protein HHCM (HHC(M)).

IBP1_HUMAN
θ value	3.0926 (rank : 564)	NC score	0.024066 (rank : 882)
Query Neighborhood Hits	671	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

LCE4A_HUMAN
θ value	3.0926 (rank : 565)	NC score	0.205512 (rank : 378)
Query Neighborhood Hits	671	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

MKS3_HUMAN
θ value	3.0926 (rank : 566)	NC score	0.158888 (rank : 452)
Query Neighborhood Hits	671	Target Neighborhood Hits	79	Shared Neighborhood Hits	76
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MT4_HUMAN
θ value	3.0926 (rank : 567)	NC score	0.182925 (rank : 408)
Query Neighborhood Hits	671	Target Neighborhood Hits	83	Shared Neighborhood Hits	76
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

NRX1A_HUMAN
θ value	3.0926 (rank : 568)	NC score	0.254427 (rank : 335)
Query Neighborhood Hits	671	Target Neighborhood Hits	170	Shared Neighborhood Hits	128
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	3.0926 (rank : 569)	NC score	0.252960 (rank : 338)
Query Neighborhood Hits	671	Target Neighborhood Hits	164	Shared Neighborhood Hits	127
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

PGCB_HUMAN
θ value	3.0926 (rank : 570)	NC score	0.225923 (rank : 357)
Query Neighborhood Hits	671	Target Neighborhood Hits	478	Shared Neighborhood Hits	180
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

SO1A1_MOUSE
θ value	3.0926 (rank : 571)	NC score	0.003442 (rank : 916)
Query Neighborhood Hits	671	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SPR2E_HUMAN
θ value	3.0926 (rank : 572)	NC score	0.076469 (rank : 654)
Query Neighborhood Hits	671	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

THYG_MOUSE
θ value	3.0926 (rank : 573)	NC score	0.061171 (rank : 721)
Query Neighborhood Hits	671	Target Neighborhood Hits	161	Shared Neighborhood Hits	79
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TNR9_HUMAN
θ value	3.0926 (rank : 574)	NC score	0.152109 (rank : 462)
Query Neighborhood Hits	671	Target Neighborhood Hits	166	Shared Neighborhood Hits	130
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TRI42_HUMAN
θ value	3.0926 (rank : 575)	NC score	0.035048 (rank : 862)
Query Neighborhood Hits	671	Target Neighborhood Hits	283	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI56_MOUSE
θ value	3.0926 (rank : 576)	NC score	0.004430 (rank : 913)
Query Neighborhood Hits	671	Target Neighborhood Hits	255	Shared Neighborhood Hits	14
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

ADA29_HUMAN
θ value	4.03905 (rank : 577)	NC score	0.126769 (rank : 513)
Query Neighborhood Hits	671	Target Neighborhood Hits	247	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

CD320_HUMAN
θ value	4.03905 (rank : 578)	NC score	0.181651 (rank : 411)
Query Neighborhood Hits	671	Target Neighborhood Hits	103	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CO8A_HUMAN
θ value	4.03905 (rank : 579)	NC score	0.135909 (rank : 499)
Query Neighborhood Hits	671	Target Neighborhood Hits	200	Shared Neighborhood Hits	117
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

DKK4_MOUSE
θ value	4.03905 (rank : 580)	NC score	0.024069 (rank : 881)
Query Neighborhood Hits	671	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VEJ3	Gene names	Dkk4
Domain Architecture	No domain graphic available
Description	Dickkopf-related protein 4 precursor (Dkk-4) (Dickkopf-4).

EMID2_MOUSE
θ value	4.03905 (rank : 581)	NC score	0.020577 (rank : 889)
Query Neighborhood Hits	671	Target Neighborhood Hits	201	Shared Neighborhood Hits	30
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EPHA3_HUMAN
θ value	4.03905 (rank : 582)	NC score	0.041983 (rank : 844)
Query Neighborhood Hits	671	Target Neighborhood Hits	1005	Shared Neighborhood Hits	107
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EZH2_HUMAN
θ value	4.03905 (rank : 583)	NC score	0.019911 (rank : 890)
Query Neighborhood Hits	671	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	4.03905 (rank : 584)	NC score	0.020577 (rank : 888)
Query Neighborhood Hits	671	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

HTRA1_HUMAN
θ value	4.03905 (rank : 585)	NC score	0.040707 (rank : 847)
Query Neighborhood Hits	671	Target Neighborhood Hits	155	Shared Neighborhood Hits	67
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HTRA3_MOUSE
θ value	4.03905 (rank : 586)	NC score	0.036226 (rank : 859)
Query Neighborhood Hits	671	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

LY10_HUMAN
θ value	4.03905 (rank : 587)	NC score	0.001911 (rank : 919)
Query Neighborhood Hits	671	Target Neighborhood Hits	151	Shared Neighborhood Hits	7
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MT1M_HUMAN
θ value	4.03905 (rank : 588)	NC score	0.091202 (rank : 601)
Query Neighborhood Hits	671	Target Neighborhood Hits	72	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

SEPP1_HUMAN
θ value	4.03905 (rank : 589)	NC score	0.012325 (rank : 899)
Query Neighborhood Hits	671	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	P49908, Q6PD59, Q6PI43, Q6PI87, Q6PJF9	Gene names	SEPP1, SELP
Domain Architecture
Description	Selenoprotein P precursor (SeP).

SPR2B_MOUSE
θ value	4.03905 (rank : 590)	NC score	0.094531 (rank : 587)
Query Neighborhood Hits	671	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPRC_MOUSE
θ value	4.03905 (rank : 591)	NC score	0.036949 (rank : 858)
Query Neighborhood Hits	671	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

TECT2_MOUSE
θ value	4.03905 (rank : 592)	NC score	0.010989 (rank : 900)
Query Neighborhood Hits	671	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q2MV57, Q6PDZ5, Q8C0B3, Q9CXF5	Gene names	Tect2
Domain Architecture	No domain graphic available
Description	Tectonic-2 precursor.

TNR8_HUMAN
θ value	4.03905 (rank : 593)	NC score	0.125711 (rank : 514)
Query Neighborhood Hits	671	Target Neighborhood Hits	198	Shared Neighborhood Hits	98
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

VEGFD_HUMAN
θ value	4.03905 (rank : 594)	NC score	0.018536 (rank : 891)
Query Neighborhood Hits	671	Target Neighborhood Hits	48	Shared Neighborhood Hits	27
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

ATS20_HUMAN
θ value	5.27518 (rank : 595)	NC score	0.064704 (rank : 708)
Query Neighborhood Hits	671	Target Neighborhood Hits	192	Shared Neighborhood Hits	116
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

BAMBI_HUMAN
θ value	5.27518 (rank : 596)	NC score	0.014341 (rank : 894)
Query Neighborhood Hits	671	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q13145	Gene names	BAMBI, NMA
Domain Architecture
Description	BMP and activin membrane-bound inhibitor homolog precursor (Putative transmembrane protein NMA) (Non-metastatic gene A protein).

CO9_HUMAN
θ value	5.27518 (rank : 597)	NC score	0.135718 (rank : 500)
Query Neighborhood Hits	671	Target Neighborhood Hits	147	Shared Neighborhood Hits	97
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

EPHA8_HUMAN
θ value	5.27518 (rank : 598)	NC score	0.028420 (rank : 875)
Query Neighborhood Hits	671	Target Neighborhood Hits	956	Shared Neighborhood Hits	65
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

FAM5B_MOUSE
θ value	5.27518 (rank : 599)	NC score	0.026713 (rank : 878)
Query Neighborhood Hits	671	Target Neighborhood Hits	51	Shared Neighborhood Hits	36
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

FSTL3_MOUSE
θ value	5.27518 (rank : 600)	NC score	0.170462 (rank : 435)
Query Neighborhood Hits	671	Target Neighborhood Hits	152	Shared Neighborhood Hits	103
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

GP128_HUMAN
θ value	5.27518 (rank : 601)	NC score	0.104166 (rank : 557)
Query Neighborhood Hits	671	Target Neighborhood Hits	135	Shared Neighborhood Hits	52
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

HYAL3_MOUSE
θ value	5.27518 (rank : 602)	NC score	0.044869 (rank : 837)
Query Neighborhood Hits	671	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

KRHB6_MOUSE
θ value	5.27518 (rank : 603)	NC score	0.000209 (rank : 923)
Query Neighborhood Hits	671	Target Neighborhood Hits	413	Shared Neighborhood Hits	28
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

LEG3_HUMAN
θ value	5.27518 (rank : 604)	NC score	0.000051 (rank : 924)
Query Neighborhood Hits	671	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

LTK_MOUSE
θ value	5.27518 (rank : 605)	NC score	0.021864 (rank : 886)
Query Neighborhood Hits	671	Target Neighborhood Hits	770	Shared Neighborhood Hits	42
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

MICA1_MOUSE
θ value	5.27518 (rank : 606)	NC score	-0.004853 (rank : 930)
Query Neighborhood Hits	671	Target Neighborhood Hits	400	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

MMRN1_HUMAN
θ value	5.27518 (rank : 607)	NC score	0.198879 (rank : 384)
Query Neighborhood Hits	671	Target Neighborhood Hits	636	Shared Neighborhood Hits	154
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

RP1L1_MOUSE
θ value	5.27518 (rank : 608)	NC score	0.005226 (rank : 911)
Query Neighborhood Hits	671	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

RRMJ3_MOUSE
θ value	5.27518 (rank : 609)	NC score	0.001450 (rank : 920)
Query Neighborhood Hits	671	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

RSPO1_HUMAN
θ value	5.27518 (rank : 610)	NC score	0.097307 (rank : 574)
Query Neighborhood Hits	671	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

SEM5B_MOUSE
θ value	5.27518 (rank : 611)	NC score	0.051462 (rank : 811)
Query Neighborhood Hits	671	Target Neighborhood Hits	190	Shared Neighborhood Hits	75
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

SO2B1_MOUSE
θ value	5.27518 (rank : 612)	NC score	0.004398 (rank : 914)
Query Neighborhood Hits	671	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

SPY4_MOUSE
θ value	5.27518 (rank : 613)	NC score	0.037336 (rank : 856)
Query Neighborhood Hits	671	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

TBCD8_HUMAN
θ value	5.27518 (rank : 614)	NC score	0.000889 (rank : 922)
Query Neighborhood Hits	671	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	O95759, Q9UQ32	Gene names	TBC1D8, VRP
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (AD 3).

TNR26_MOUSE
θ value	5.27518 (rank : 615)	NC score	0.100645 (rank : 567)
Query Neighborhood Hits	671	Target Neighborhood Hits	106	Shared Neighborhood Hits	79
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR7_MOUSE
θ value	5.27518 (rank : 616)	NC score	0.102686 (rank : 561)
Query Neighborhood Hits	671	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

WISP1_MOUSE
θ value	5.27518 (rank : 617)	NC score	0.086011 (rank : 615)
Query Neighborhood Hits	671	Target Neighborhood Hits	123	Shared Neighborhood Hits	78
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ACCN4_MOUSE
θ value	6.88961 (rank : 618)	NC score	0.002088 (rank : 918)
Query Neighborhood Hits	671	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TNS7, Q80XK4	Gene names	Accn4, Asic4
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 4 (Acid-sensing ion channel 4).

BAI3_MOUSE
θ value	6.88961 (rank : 619)	NC score	0.108041 (rank : 548)
Query Neighborhood Hits	671	Target Neighborhood Hits	250	Shared Neighborhood Hits	87
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BEGIN_HUMAN
θ value	6.88961 (rank : 620)	NC score	-0.005246 (rank : 931)
Query Neighborhood Hits	671	Target Neighborhood Hits	454	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

CO9_MOUSE
θ value	6.88961 (rank : 621)	NC score	0.143859 (rank : 482)
Query Neighborhood Hits	671	Target Neighborhood Hits	153	Shared Neighborhood Hits	105
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

DB131_HUMAN
θ value	6.88961 (rank : 622)	NC score	0.009314 (rank : 905)
Query Neighborhood Hits	671	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P59861	Gene names	DEFB131, DEFB31
Domain Architecture	No domain graphic available
Description	Beta-defensin 131 precursor (Defensin, beta 131) (Beta-defensin 31) (DEFB-31).

EPHA5_HUMAN
θ value	6.88961 (rank : 623)	NC score	0.036071 (rank : 860)
Query Neighborhood Hits	671	Target Neighborhood Hits	1009	Shared Neighborhood Hits	83
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EREG_MOUSE
θ value	6.88961 (rank : 624)	NC score	0.096614 (rank : 577)
Query Neighborhood Hits	671	Target Neighborhood Hits	65	Shared Neighborhood Hits	52
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

EZH1_HUMAN
θ value	6.88961 (rank : 625)	NC score	0.022939 (rank : 884)
Query Neighborhood Hits	671	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	6.88961 (rank : 626)	NC score	0.023922 (rank : 883)
Query Neighborhood Hits	671	Target Neighborhood Hits	126	Shared Neighborhood Hits	55
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

FAM5B_HUMAN
θ value	6.88961 (rank : 627)	NC score	0.026924 (rank : 877)
Query Neighborhood Hits	671	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

HAIR_HUMAN
θ value	6.88961 (rank : 628)	NC score	0.004119 (rank : 915)
Query Neighborhood Hits	671	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

HCN2_MOUSE
θ value	6.88961 (rank : 629)	NC score	-0.001166 (rank : 925)
Query Neighborhood Hits	671	Target Neighborhood Hits	278	Shared Neighborhood Hits	7
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

KAZD1_MOUSE
θ value	6.88961 (rank : 630)	NC score	0.031626 (rank : 867)
Query Neighborhood Hits	671	Target Neighborhood Hits	281	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KR192_HUMAN
θ value	6.88961 (rank : 631)	NC score	0.029501 (rank : 872)
Query Neighborhood Hits	671	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q3LHN2	Gene names	KRTAP19-2, KAP19.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 19-2.

MYCB2_HUMAN
θ value	6.88961 (rank : 632)	NC score	0.012729 (rank : 897)
Query Neighborhood Hits	671	Target Neighborhood Hits	390	Shared Neighborhood Hits	31
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_MOUSE
θ value	6.88961 (rank : 633)	NC score	0.009744 (rank : 904)
Query Neighborhood Hits	671	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NRG1_HUMAN
θ value	6.88961 (rank : 634)	NC score	0.175015 (rank : 427)
Query Neighborhood Hits	671	Target Neighborhood Hits	285	Shared Neighborhood Hits	102
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG4_MOUSE
θ value	6.88961 (rank : 635)	NC score	0.166645 (rank : 440)
Query Neighborhood Hits	671	Target Neighborhood Hits	79	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

RON_HUMAN
θ value	6.88961 (rank : 636)	NC score	0.016883 (rank : 892)
Query Neighborhood Hits	671	Target Neighborhood Hits	842	Shared Neighborhood Hits	46
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RP1L1_HUMAN
θ value	6.88961 (rank : 637)	NC score	-0.004806 (rank : 929)
Query Neighborhood Hits	671	Target Neighborhood Hits	1072	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SEM5B_HUMAN
θ value	6.88961 (rank : 638)	NC score	0.046971 (rank : 831)
Query Neighborhood Hits	671	Target Neighborhood Hits	178	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SPR2D_HUMAN
θ value	6.88961 (rank : 639)	NC score	0.054061 (rank : 787)
Query Neighborhood Hits	671	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

SPY4_HUMAN
θ value	6.88961 (rank : 640)	NC score	0.025146 (rank : 880)
Query Neighborhood Hits	671	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	Q9C004, Q6QIX2, Q9C003	Gene names	SPRY4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

TGFA_HUMAN
θ value	6.88961 (rank : 641)	NC score	0.092162 (rank : 597)
Query Neighborhood Hits	671	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TIAF1_HUMAN
θ value	6.88961 (rank : 642)	NC score	0.007932 (rank : 908)
Query Neighborhood Hits	671	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	O95411, Q6PEG2	Gene names	TIAF1
Domain Architecture	No domain graphic available
Description	TGFB1-induced anti-apoptotic factor 1 (12 kDa TGF-beta1-induced antiapoptotic factor).

TIAF1_MOUSE
θ value	6.88961 (rank : 643)	NC score	0.007932 (rank : 909)
Query Neighborhood Hits	671	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1S4	Gene names	Tiaf1
Domain Architecture	No domain graphic available
Description	TGFB1-induced anti-apoptotic factor 1 (12 kDa TGF-beta1-induced antiapoptotic factor).

TNR19_HUMAN
θ value	6.88961 (rank : 644)	NC score	0.083312 (rank : 626)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TR11B_HUMAN
θ value	6.88961 (rank : 645)	NC score	0.057825 (rank : 749)
Query Neighborhood Hits	671	Target Neighborhood Hits	92	Shared Neighborhood Hits	59
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

ADA20_HUMAN
θ value	8.99809 (rank : 646)	NC score	0.101915 (rank : 565)
Query Neighborhood Hits	671	Target Neighborhood Hits	143	Shared Neighborhood Hits	103
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA24_MOUSE
θ value	8.99809 (rank : 647)	NC score	0.143269 (rank : 483)
Query Neighborhood Hits	671	Target Neighborhood Hits	230	Shared Neighborhood Hits	183
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ATS8_HUMAN
θ value	8.99809 (rank : 648)	NC score	0.046597 (rank : 834)
Query Neighborhood Hits	671	Target Neighborhood Hits	145	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

C1QT7_HUMAN
θ value	8.99809 (rank : 649)	NC score	-0.003238 (rank : 928)
Query Neighborhood Hits	671	Target Neighborhood Hits	119	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BXJ2	Gene names	C1QTNF7, CTRP7
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

CB027_HUMAN
θ value	8.99809 (rank : 650)	NC score	0.004969 (rank : 912)
Query Neighborhood Hits	671	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q580R0, O43575, Q52M10, Q86XG2	Gene names	C2orf27
Domain Architecture	No domain graphic available
Description	Protein C2orf27.

CO1A1_MOUSE
θ value	8.99809 (rank : 651)	NC score	0.025860 (rank : 879)
Query Neighborhood Hits	671	Target Neighborhood Hits	457	Shared Neighborhood Hits	62
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

DKK3_HUMAN
θ value	8.99809 (rank : 652)	NC score	0.102650 (rank : 562)
Query Neighborhood Hits	671	Target Neighborhood Hits	74	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

E2AK3_MOUSE
θ value	8.99809 (rank : 653)	NC score	-0.003158 (rank : 927)
Query Neighborhood Hits	671	Target Neighborhood Hits	851	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z2B5, Q9CTK8, Q9CWT5	Gene names	Eif2ak3, Pek, Perk
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase).

EMID2_HUMAN
θ value	8.99809 (rank : 654)	NC score	0.012683 (rank : 898)
Query Neighborhood Hits	671	Target Neighborhood Hits	226	Shared Neighborhood Hits	27
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EOMES_HUMAN
θ value	8.99809 (rank : 655)	NC score	-0.001626 (rank : 926)
Query Neighborhood Hits	671	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

F13B_MOUSE
θ value	8.99809 (rank : 656)	NC score	0.040082 (rank : 852)
Query Neighborhood Hits	671	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

HTRA3_HUMAN
θ value	8.99809 (rank : 657)	NC score	0.035022 (rank : 863)
Query Neighborhood Hits	671	Target Neighborhood Hits	152	Shared Neighborhood Hits	55
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HYAL3_HUMAN
θ value	8.99809 (rank : 658)	NC score	0.040562 (rank : 848)
Query Neighborhood Hits	671	Target Neighborhood Hits	45	Shared Neighborhood Hits	36
SwissProt Accessions	O43820, O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9	Gene names	HYAL3, LUCA3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3) (LUCA-3).

KR122_HUMAN
θ value	8.99809 (rank : 659)	NC score	0.149995 (rank : 467)
Query Neighborhood Hits	671	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

LCE3B_HUMAN
θ value	8.99809 (rank : 660)	NC score	0.142338 (rank : 486)
Query Neighborhood Hits	671	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

MEP1B_MOUSE
θ value	8.99809 (rank : 661)	NC score	0.134194 (rank : 502)
Query Neighborhood Hits	671	Target Neighborhood Hits	127	Shared Neighborhood Hits	88
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MT1G_HUMAN
θ value	8.99809 (rank : 662)	NC score	0.104007 (rank : 558)
Query Neighborhood Hits	671	Target Neighborhood Hits	63	Shared Neighborhood Hits	57
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

NRG3_HUMAN
θ value	8.99809 (rank : 663)	NC score	0.077706 (rank : 649)
Query Neighborhood Hits	671	Target Neighborhood Hits	119	Shared Neighborhood Hits	67
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRG3_MOUSE
θ value	8.99809 (rank : 664)	NC score	0.080791 (rank : 638)
Query Neighborhood Hits	671	Target Neighborhood Hits	132	Shared Neighborhood Hits	73
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

RECK_HUMAN
θ value	8.99809 (rank : 665)	NC score	0.224442 (rank : 358)
Query Neighborhood Hits	671	Target Neighborhood Hits	189	Shared Neighborhood Hits	136
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RSPO1_MOUSE
θ value	8.99809 (rank : 666)	NC score	0.082051 (rank : 632)
Query Neighborhood Hits	671	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

SO2A1_MOUSE
θ value	8.99809 (rank : 667)	NC score	0.008851 (rank : 907)
Query Neighborhood Hits	671	Target Neighborhood Hits	51	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

TGFA_MOUSE
θ value	8.99809 (rank : 668)	NC score	0.075347 (rank : 658)
Query Neighborhood Hits	671	Target Neighborhood Hits	62	Shared Neighborhood Hits	51
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

TICN1_MOUSE
θ value	8.99809 (rank : 669)	NC score	0.028276 (rank : 876)
Query Neighborhood Hits	671	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TR11B_MOUSE
θ value	8.99809 (rank : 670)	NC score	0.057143 (rank : 752)
Query Neighborhood Hits	671	Target Neighborhood Hits	95	Shared Neighborhood Hits	60
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

ZNF85_HUMAN
θ value	8.99809 (rank : 671)	NC score	-0.015705 (rank : 932)
Query Neighborhood Hits	671	Target Neighborhood Hits	770	Shared Neighborhood Hits	14
SwissProt Accessions	Q03923	Gene names	ZNF85
Domain Architecture
Description	Zinc finger protein 85 (Zinc finger protein HPF4) (HTF1).

ADAM2_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.148586 (rank : 469)
Query Neighborhood Hits	671	Target Neighborhood Hits	175	Shared Neighborhood Hits	145
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADEC1_HUMAN
θ value	θ > 10 (rank : 673)	NC score	0.066841 (rank : 696)
Query Neighborhood Hits	671	Target Neighborhood Hits	80	Shared Neighborhood Hits	47
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ADEC1_MOUSE
θ value	θ > 10 (rank : 674)	NC score	0.068959 (rank : 689)
Query Neighborhood Hits	671	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

ANGL1_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.055658 (rank : 771)
Query Neighborhood Hits	671	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	O95841, Q5T5Z5	Gene names	ANGPTL1, ANG3, ANGPT3, ARP1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1) (Angiopoietin-3) (ANG-3).

ANGL1_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.056131 (rank : 766)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q640P2, Q3UQL1, Q9CZ81	Gene names	Angptl1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1).

ANGL2_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.056664 (rank : 757)
Query Neighborhood Hits	671	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL2_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.056800 (rank : 754)
Query Neighborhood Hits	671	Target Neighborhood Hits	108	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL3_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.054618 (rank : 783)
Query Neighborhood Hits	671	Target Neighborhood Hits	306	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

ANGL4_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.054264 (rank : 786)
Query Neighborhood Hits	671	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

ANGL4_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.054840 (rank : 781)
Query Neighborhood Hits	671	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1P8, Q78ZJ9, Q9JHX7, Q9JLX7	Gene names	Angptl4, Farp, Fiaf, Ng27
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Fasting- induced adipose factor) (Secreted protein Bk89) (425O18-1).

ANGL5_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.059806 (rank : 730)
Query Neighborhood Hits	671	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

ANGL6_HUMAN
θ value	θ > 10 (rank : 683)	NC score	0.058876 (rank : 738)
Query Neighborhood Hits	671	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

ANGL6_MOUSE
θ value	θ > 10 (rank : 684)	NC score	0.060619 (rank : 726)
Query Neighborhood Hits	671	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0Z6	Gene names	Angptl6, Agf
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor).

ANGL7_HUMAN
θ value	θ > 10 (rank : 685)	NC score	0.060588 (rank : 727)
Query Neighborhood Hits	671	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	O43827, Q4ZGK4	Gene names	ANGPTL7, CDT6
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7) (Angiopoietin-like factor) (Cornea-derived transcript 6 protein).

ANGL7_MOUSE
θ value	θ > 10 (rank : 686)	NC score	0.060832 (rank : 723)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

ANGP1_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.054942 (rank : 777)
Query Neighborhood Hits	671	Target Neighborhood Hits	254	Shared Neighborhood Hits	11
SwissProt Accessions	Q15389	Gene names	ANGPT1, KIAA0003
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP1_MOUSE
θ value	θ > 10 (rank : 688)	NC score	0.052828 (rank : 798)
Query Neighborhood Hits	671	Target Neighborhood Hits	252	Shared Neighborhood Hits	10
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP4_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.056576 (rank : 760)
Query Neighborhood Hits	671	Target Neighborhood Hits	187	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ANGP4_MOUSE
θ value	θ > 10 (rank : 690)	NC score	0.053431 (rank : 794)
Query Neighborhood Hits	671	Target Neighborhood Hits	220	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WVH6	Gene names	Angpt4, Agpt4, Ang3
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ANR15_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.051937 (rank : 806)
Query Neighborhood Hits	671	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR38_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.053364 (rank : 795)
Query Neighborhood Hits	671	Target Neighborhood Hits	443	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR38_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.054902 (rank : 778)
Query Neighborhood Hits	671	Target Neighborhood Hits	512	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

APR3_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.145688 (rank : 479)
Query Neighborhood Hits	671	Target Neighborhood Hits	50	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

ASB16_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.051565 (rank : 809)
Query Neighborhood Hits	671	Target Neighborhood Hits	306	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASTL_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.056460 (rank : 763)
Query Neighborhood Hits	671	Target Neighborhood Hits	252	Shared Neighborhood Hits	19
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_MOUSE
θ value	θ > 10 (rank : 697)	NC score	0.050596 (rank : 821)
Query Neighborhood Hits	671	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ATS12_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.050869 (rank : 817)
Query Neighborhood Hits	671	Target Neighborhood Hits	251	Shared Neighborhood Hits	106
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS12_MOUSE
θ value	θ > 10 (rank : 699)	NC score	0.053444 (rank : 793)
Query Neighborhood Hits	671	Target Neighborhood Hits	220	Shared Neighborhood Hits	111
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS16_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.056437 (rank : 765)
Query Neighborhood Hits	671	Target Neighborhood Hits	208	Shared Neighborhood Hits	121
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_MOUSE
θ value	θ > 10 (rank : 701)	NC score	0.052891 (rank : 796)
Query Neighborhood Hits	671	Target Neighborhood Hits	179	Shared Neighborhood Hits	109
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS17_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.054472 (rank : 785)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	100
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS18_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.052748 (rank : 800)
Query Neighborhood Hits	671	Target Neighborhood Hits	169	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS1_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.050979 (rank : 816)
Query Neighborhood Hits	671	Target Neighborhood Hits	158	Shared Neighborhood Hits	95
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS6_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.052875 (rank : 797)
Query Neighborhood Hits	671	Target Neighborhood Hits	141	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS7_HUMAN
θ value	θ > 10 (rank : 706)	NC score	0.060724 (rank : 725)
Query Neighborhood Hits	671	Target Neighborhood Hits	169	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS9_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.077954 (rank : 648)
Query Neighborhood Hits	671	Target Neighborhood Hits	219	Shared Neighborhood Hits	139
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

BAI1_MOUSE
θ value	θ > 10 (rank : 708)	NC score	0.103418 (rank : 559)
Query Neighborhood Hits	671	Target Neighborhood Hits	340	Shared Neighborhood Hits	81
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.099805 (rank : 570)
Query Neighborhood Hits	671	Target Neighborhood Hits	332	Shared Neighborhood Hits	81
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 710)	NC score	0.101615 (rank : 566)
Query Neighborhood Hits	671	Target Neighborhood Hits	323	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.104526 (rank : 555)
Query Neighborhood Hits	671	Target Neighborhood Hits	246	Shared Neighborhood Hits	85
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BTC_HUMAN
θ value	θ > 10 (rank : 712)	NC score	0.104206 (rank : 556)
Query Neighborhood Hits	671	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CD2A1_MOUSE
θ value	θ > 10 (rank : 713)	NC score	0.061844 (rank : 718)
Query Neighborhood Hits	671	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CDN2B_HUMAN
θ value	θ > 10 (rank : 714)	NC score	0.062242 (rank : 716)
Query Neighborhood Hits	671	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CDN2B_MOUSE
θ value	θ > 10 (rank : 715)	NC score	0.055059 (rank : 776)
Query Neighborhood Hits	671	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CFAB_HUMAN
θ value	θ > 10 (rank : 716)	NC score	0.057959 (rank : 748)
Query Neighborhood Hits	671	Target Neighborhood Hits	251	Shared Neighborhood Hits	57
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
θ value	θ > 10 (rank : 717)	NC score	0.069756 (rank : 686)
Query Neighborhood Hits	671	Target Neighborhood Hits	262	Shared Neighborhood Hits	64
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAI_MOUSE
θ value	θ > 10 (rank : 718)	NC score	0.096063 (rank : 580)
Query Neighborhood Hits	671	Target Neighborhood Hits	290	Shared Neighborhood Hits	92
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CHRD_HUMAN
θ value	θ > 10 (rank : 719)	NC score	0.111212 (rank : 539)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 720)	NC score	0.107681 (rank : 549)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CNTP1_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.180442 (rank : 414)
Query Neighborhood Hits	671	Target Neighborhood Hits	196	Shared Neighborhood Hits	116
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 722)	NC score	0.173477 (rank : 432)
Query Neighborhood Hits	671	Target Neighborhood Hits	183	Shared Neighborhood Hits	107
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP3_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.193579 (rank : 393)
Query Neighborhood Hits	671	Target Neighborhood Hits	195	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.204503 (rank : 381)
Query Neighborhood Hits	671	Target Neighborhood Hits	187	Shared Neighborhood Hits	119
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 725)	NC score	0.207358 (rank : 374)
Query Neighborhood Hits	671	Target Neighborhood Hits	193	Shared Neighborhood Hits	137
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO2_HUMAN
θ value	θ > 10 (rank : 726)	NC score	0.056634 (rank : 758)
Query Neighborhood Hits	671	Target Neighborhood Hits	258	Shared Neighborhood Hits	62
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 727)	NC score	0.056533 (rank : 761)
Query Neighborhood Hits	671	Target Neighborhood Hits	250	Shared Neighborhood Hits	61
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO6A3_HUMAN
θ value	θ > 10 (rank : 728)	NC score	0.055341 (rank : 774)
Query Neighborhood Hits	671	Target Neighborhood Hits	317	Shared Neighborhood Hits	31
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

CO7A1_HUMAN
θ value	θ > 10 (rank : 729)	NC score	0.086007 (rank : 616)
Query Neighborhood Hits	671	Target Neighborhood Hits	807	Shared Neighborhood Hits	76
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO7_HUMAN
θ value	θ > 10 (rank : 730)	NC score	0.194854 (rank : 389)
Query Neighborhood Hits	671	Target Neighborhood Hits	278	Shared Neighborhood Hits	158
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_MOUSE
θ value	θ > 10 (rank : 731)	NC score	0.124505 (rank : 515)
Query Neighborhood Hits	671	Target Neighborhood Hits	182	Shared Neighborhood Hits	98
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

COCA1_HUMAN
θ value	θ > 10 (rank : 732)	NC score	0.113490 (rank : 537)
Query Neighborhood Hits	671	Target Neighborhood Hits	458	Shared Neighborhood Hits	56
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 733)	NC score	0.116080 (rank : 525)
Query Neighborhood Hits	671	Target Neighborhood Hits	467	Shared Neighborhood Hits	57
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCH_HUMAN
θ value	θ > 10 (rank : 734)	NC score	0.073829 (rank : 666)
Query Neighborhood Hits	671	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COCH_MOUSE
θ value	θ > 10 (rank : 735)	NC score	0.074053 (rank : 665)
Query Neighborhood Hits	671	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COEA1_HUMAN
θ value	θ > 10 (rank : 736)	NC score	0.104876 (rank : 553)
Query Neighborhood Hits	671	Target Neighborhood Hits	427	Shared Neighborhood Hits	47
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 737)	NC score	0.108255 (rank : 547)
Query Neighborhood Hits	671	Target Neighborhood Hits	402	Shared Neighborhood Hits	41
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 738)	NC score	0.115063 (rank : 530)
Query Neighborhood Hits	671	Target Neighborhood Hits	403	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

CR001_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.055650 (rank : 772)
Query Neighborhood Hits	671	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

CR001_MOUSE
θ value	θ > 10 (rank : 740)	NC score	0.054873 (rank : 780)
Query Neighborhood Hits	671	Target Neighborhood Hits	67	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

CRDL1_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.073774 (rank : 669)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
θ value	θ > 10 (rank : 742)	NC score	0.075266 (rank : 659)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	59
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 743)	NC score	0.091727 (rank : 598)
Query Neighborhood Hits	671	Target Neighborhood Hits	99	Shared Neighborhood Hits	67
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 744)	NC score	0.096861 (rank : 576)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CSMD1_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.102441 (rank : 564)
Query Neighborhood Hits	671	Target Neighborhood Hits	176	Shared Neighborhood Hits	65
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 746)	NC score	0.104690 (rank : 554)
Query Neighborhood Hits	671	Target Neighborhood Hits	193	Shared Neighborhood Hits	76
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 747)	NC score	0.093760 (rank : 591)
Query Neighborhood Hits	671	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.100427 (rank : 568)
Query Neighborhood Hits	671	Target Neighborhood Hits	199	Shared Neighborhood Hits	70
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSPG4_HUMAN
θ value	θ > 10 (rank : 749)	NC score	0.073699 (rank : 670)
Query Neighborhood Hits	671	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 750)	NC score	0.070999 (rank : 682)
Query Neighborhood Hits	671	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CUZD1_HUMAN
θ value	θ > 10 (rank : 751)	NC score	0.086219 (rank : 614)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	31
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 752)	NC score	0.080896 (rank : 637)
Query Neighborhood Hits	671	Target Neighborhood Hits	91	Shared Neighborhood Hits	29
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.068389 (rank : 692)
Query Neighborhood Hits	671	Target Neighborhood Hits	110	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	θ > 10 (rank : 754)	NC score	0.066903 (rank : 695)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.064202 (rank : 709)
Query Neighborhood Hits	671	Target Neighborhood Hits	118	Shared Neighborhood Hits	31
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 756)	NC score	0.060962 (rank : 722)
Query Neighborhood Hits	671	Target Neighborhood Hits	113	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DKK3_MOUSE
θ value	θ > 10 (rank : 757)	NC score	0.110646 (rank : 540)
Query Neighborhood Hits	671	Target Neighborhood Hits	83	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

DMBT1_HUMAN
θ value	θ > 10 (rank : 758)	NC score	0.061426 (rank : 719)
Query Neighborhood Hits	671	Target Neighborhood Hits	152	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 759)	NC score	0.073797 (rank : 667)
Query Neighborhood Hits	671	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

ENTK_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.075571 (rank : 657)
Query Neighborhood Hits	671	Target Neighborhood Hits	310	Shared Neighborhood Hits	82
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_MOUSE
θ value	θ > 10 (rank : 761)	NC score	0.081561 (rank : 634)
Query Neighborhood Hits	671	Target Neighborhood Hits	338	Shared Neighborhood Hits	88
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

EPGN_HUMAN
θ value	θ > 10 (rank : 762)	NC score	0.095590 (rank : 582)
Query Neighborhood Hits	671	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EPGN_MOUSE
θ value	θ > 10 (rank : 763)	NC score	0.108385 (rank : 546)
Query Neighborhood Hits	671	Target Neighborhood Hits	63	Shared Neighborhood Hits	54
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

FCN1_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.059372 (rank : 734)
Query Neighborhood Hits	671	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	O00602, Q92596	Gene names	FCN1
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FCN1_MOUSE
θ value	θ > 10 (rank : 765)	NC score	0.058599 (rank : 743)
Query Neighborhood Hits	671	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FCN2_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.063180 (rank : 712)
Query Neighborhood Hits	671	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q15485, Q9UC57	Gene names	FCN2
Domain Architecture
Description	Ficolin-2 precursor (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin B) (Serum lectin p35) (EBP-37) (Hucolin) (L- Ficolin).

FCN3_HUMAN
θ value	θ > 10 (rank : 767)	NC score	0.064200 (rank : 710)
Query Neighborhood Hits	671	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

FGL1_HUMAN
θ value	θ > 10 (rank : 768)	NC score	0.060446 (rank : 728)
Query Neighborhood Hits	671	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q08830, Q4PJH9, Q96KW6, Q96QM6	Gene names	FGL1, HFREP1
Domain Architecture
Description	Fibrinogen-like protein 1 precursor (Hepatocyte-derived fibrinogen- related protein 1) (HFREP-1) (Hepassocin) (HP-041).

FGL2_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.058733 (rank : 741)
Query Neighborhood Hits	671	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q14314	Gene names	FGL2
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (pT49).

FGL2_MOUSE
θ value	θ > 10 (rank : 770)	NC score	0.059383 (rank : 733)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

FIBA_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.059092 (rank : 737)
Query Neighborhood Hits	671	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

FIBB_HUMAN
θ value	θ > 10 (rank : 772)	NC score	0.056774 (rank : 755)
Query Neighborhood Hits	671	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	P02675	Gene names	FGB
Domain Architecture
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

FIBB_MOUSE
θ value	θ > 10 (rank : 773)	NC score	0.056708 (rank : 756)
Query Neighborhood Hits	671	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0E8, Q91ZP1	Gene names	Fgb
Domain Architecture	No domain graphic available
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

FIBG_HUMAN
θ value	θ > 10 (rank : 774)	NC score	0.051506 (rank : 810)
Query Neighborhood Hits	671	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	P02679, P04469, P04470, Q96A14, Q96KJ3	Gene names	FGG
Domain Architecture
Description	Fibrinogen gamma chain precursor.

FIBG_MOUSE
θ value	θ > 10 (rank : 775)	NC score	0.052038 (rank : 804)
Query Neighborhood Hits	671	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCM7, Q8WUR3, Q91ZP0	Gene names	Fgg
Domain Architecture	No domain graphic available
Description	Fibrinogen gamma chain precursor.

FINC_HUMAN
θ value	θ > 10 (rank : 776)	NC score	0.122981 (rank : 517)
Query Neighborhood Hits	671	Target Neighborhood Hits	302	Shared Neighborhood Hits	74
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 777)	NC score	0.124260 (rank : 516)
Query Neighborhood Hits	671	Target Neighborhood Hits	309	Shared Neighborhood Hits	77
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FNDC3_HUMAN
θ value	θ > 10 (rank : 778)	NC score	0.065663 (rank : 705)
Query Neighborhood Hits	671	Target Neighborhood Hits	196	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	θ > 10 (rank : 779)	NC score	0.072019 (rank : 679)
Query Neighborhood Hits	671	Target Neighborhood Hits	207	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FSTL3_HUMAN
θ value	θ > 10 (rank : 780)	NC score	0.177048 (rank : 421)
Query Neighborhood Hits	671	Target Neighborhood Hits	162	Shared Neighborhood Hits	108
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.135206 (rank : 501)
Query Neighborhood Hits	671	Target Neighborhood Hits	129	Shared Neighborhood Hits	79
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 782)	NC score	0.151376 (rank : 466)
Query Neighborhood Hits	671	Target Neighborhood Hits	146	Shared Neighborhood Hits	96
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GLU2B_HUMAN
θ value	θ > 10 (rank : 783)	NC score	0.055968 (rank : 768)
Query Neighborhood Hits	671	Target Neighborhood Hits	377	Shared Neighborhood Hits	39
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

GNPTA_MOUSE
θ value	θ > 10 (rank : 784)	NC score	0.085870 (rank : 617)
Query Neighborhood Hits	671	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GP110_HUMAN
θ value	θ > 10 (rank : 785)	NC score	0.072703 (rank : 674)
Query Neighborhood Hits	671	Target Neighborhood Hits	87	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

GP110_MOUSE
θ value	θ > 10 (rank : 786)	NC score	0.072951 (rank : 672)
Query Neighborhood Hits	671	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

GP111_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.066607 (rank : 698)
Query Neighborhood Hits	671	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

GP112_HUMAN
θ value	θ > 10 (rank : 788)	NC score	0.082902 (rank : 629)
Query Neighborhood Hits	671	Target Neighborhood Hits	441	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

GP113_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.092725 (rank : 596)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP114_HUMAN
θ value	θ > 10 (rank : 790)	NC score	0.079390 (rank : 643)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP115_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.067312 (rank : 693)
Query Neighborhood Hits	671	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GP115_MOUSE
θ value	θ > 10 (rank : 792)	NC score	0.069207 (rank : 688)
Query Neighborhood Hits	671	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP116_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.079870 (rank : 641)
Query Neighborhood Hits	671	Target Neighborhood Hits	167	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP123_HUMAN
θ value	θ > 10 (rank : 794)	NC score	0.063265 (rank : 711)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	25
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

GP124_HUMAN
θ value	θ > 10 (rank : 795)	NC score	0.058846 (rank : 740)
Query Neighborhood Hits	671	Target Neighborhood Hits	304	Shared Neighborhood Hits	30
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP124_MOUSE
θ value	θ > 10 (rank : 796)	NC score	0.061998 (rank : 717)
Query Neighborhood Hits	671	Target Neighborhood Hits	423	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
θ value	θ > 10 (rank : 797)	NC score	0.062507 (rank : 715)
Query Neighborhood Hits	671	Target Neighborhood Hits	327	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	θ > 10 (rank : 798)	NC score	0.058022 (rank : 747)
Query Neighborhood Hits	671	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP126_HUMAN
θ value	θ > 10 (rank : 799)	NC score	0.110633 (rank : 541)
Query Neighborhood Hits	671	Target Neighborhood Hits	187	Shared Neighborhood Hits	42
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GP133_HUMAN
θ value	θ > 10 (rank : 800)	NC score	0.085201 (rank : 620)
Query Neighborhood Hits	671	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

GP144_HUMAN
θ value	θ > 10 (rank : 801)	NC score	0.088582 (rank : 604)
Query Neighborhood Hits	671	Target Neighborhood Hits	108	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GP179_HUMAN
θ value	θ > 10 (rank : 802)	NC score	0.056587 (rank : 759)
Query Neighborhood Hits	671	Target Neighborhood Hits	372	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GP2_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.050631 (rank : 819)
Query Neighborhood Hits	671	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	P55259, Q13338, Q9UIF1	Gene names	GP2
Domain Architecture
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2) (ZAP75).

GPR56_HUMAN
θ value	θ > 10 (rank : 804)	NC score	0.074319 (rank : 664)
Query Neighborhood Hits	671	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GPR56_MOUSE
θ value	θ > 10 (rank : 805)	NC score	0.074513 (rank : 663)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

GPR64_HUMAN
θ value	θ > 10 (rank : 806)	NC score	0.077420 (rank : 652)
Query Neighborhood Hits	671	Target Neighborhood Hits	207	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GPR64_MOUSE
θ value	θ > 10 (rank : 807)	NC score	0.077970 (rank : 647)
Query Neighborhood Hits	671	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GPR97_HUMAN
θ value	θ > 10 (rank : 808)	NC score	0.068823 (rank : 690)
Query Neighborhood Hits	671	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GPR97_MOUSE
θ value	θ > 10 (rank : 809)	NC score	0.075094 (rank : 661)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GPR98_HUMAN
θ value	θ > 10 (rank : 810)	NC score	0.071828 (rank : 680)
Query Neighborhood Hits	671	Target Neighborhood Hits	202	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
θ value	θ > 10 (rank : 811)	NC score	0.069349 (rank : 687)
Query Neighborhood Hits	671	Target Neighborhood Hits	206	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

HBEGF_HUMAN
θ value	θ > 10 (rank : 812)	NC score	0.084074 (rank : 624)
Query Neighborhood Hits	671	Target Neighborhood Hits	61	Shared Neighborhood Hits	51
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

HBEGF_MOUSE
θ value	θ > 10 (rank : 813)	NC score	0.059995 (rank : 729)
Query Neighborhood Hits	671	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

HPTR_HUMAN
θ value	θ > 10 (rank : 814)	NC score	0.054524 (rank : 784)
Query Neighborhood Hits	671	Target Neighborhood Hits	166	Shared Neighborhood Hits	34
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 815)	NC score	0.054881 (rank : 779)
Query Neighborhood Hits	671	Target Neighborhood Hits	184	Shared Neighborhood Hits	37
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 816)	NC score	0.053549 (rank : 791)
Query Neighborhood Hits	671	Target Neighborhood Hits	178	Shared Neighborhood Hits	34
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

IDD_HUMAN
θ value	θ > 10 (rank : 817)	NC score	0.093657 (rank : 592)
Query Neighborhood Hits	671	Target Neighborhood Hits	127	Shared Neighborhood Hits	50
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

IDD_MOUSE
θ value	θ > 10 (rank : 818)	NC score	0.089295 (rank : 603)
Query Neighborhood Hits	671	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

INSR_MOUSE
θ value	θ > 10 (rank : 819)	NC score	0.051400 (rank : 812)
Query Neighborhood Hits	671	Target Neighborhood Hits	968	Shared Neighborhood Hits	136
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

KR111_HUMAN
θ value	θ > 10 (rank : 820)	NC score	0.117010 (rank : 523)
Query Neighborhood Hits	671	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR123_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.113591 (rank : 536)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

KR124_HUMAN
θ value	θ > 10 (rank : 822)	NC score	0.164785 (rank : 443)
Query Neighborhood Hits	671	Target Neighborhood Hits	124	Shared Neighborhood Hits	97
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR131_HUMAN
θ value	θ > 10 (rank : 823)	NC score	0.091220 (rank : 600)
Query Neighborhood Hits	671	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

KR132_HUMAN
θ value	θ > 10 (rank : 824)	NC score	0.067032 (rank : 694)
Query Neighborhood Hits	671	Target Neighborhood Hits	69	Shared Neighborhood Hits	48
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

KR133_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.065176 (rank : 707)
Query Neighborhood Hits	671	Target Neighborhood Hits	66	Shared Neighborhood Hits	50
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

KR134_HUMAN
θ value	θ > 10 (rank : 826)	NC score	0.078718 (rank : 645)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	54
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KR241_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.096327 (rank : 578)
Query Neighborhood Hits	671	Target Neighborhood Hits	71	Shared Neighborhood Hits	50
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KR261_HUMAN
θ value	θ > 10 (rank : 828)	NC score	0.087879 (rank : 606)
Query Neighborhood Hits	671	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

KR413_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.206391 (rank : 376)
Query Neighborhood Hits	671	Target Neighborhood Hits	112	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 830)	NC score	0.370319 (rank : 273)
Query Neighborhood Hits	671	Target Neighborhood Hits	199	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KRA42_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.274881 (rank : 327)
Query Neighborhood Hits	671	Target Neighborhood Hits	149	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 832)	NC score	0.370819 (rank : 272)
Query Neighborhood Hits	671	Target Neighborhood Hits	162	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA63_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.059739 (rank : 731)
Query Neighborhood Hits	671	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q3LI67	Gene names	KRTAP6-3, KAP6.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-3.

KREM1_HUMAN
θ value	θ > 10 (rank : 834)	NC score	0.059327 (rank : 735)
Query Neighborhood Hits	671	Target Neighborhood Hits	90	Shared Neighborhood Hits	32
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 835)	NC score	0.059699 (rank : 732)
Query Neighborhood Hits	671	Target Neighborhood Hits	92	Shared Neighborhood Hits	34
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 836)	NC score	0.062581 (rank : 714)
Query Neighborhood Hits	671	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 837)	NC score	0.056871 (rank : 753)
Query Neighborhood Hits	671	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LCE3C_HUMAN
θ value	θ > 10 (rank : 838)	NC score	0.094013 (rank : 590)
Query Neighborhood Hits	671	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LPHN1_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.082284 (rank : 631)
Query Neighborhood Hits	671	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 840)	NC score	0.083608 (rank : 625)
Query Neighborhood Hits	671	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

LPHN3_HUMAN
θ value	θ > 10 (rank : 841)	NC score	0.083149 (rank : 628)
Query Neighborhood Hits	671	Target Neighborhood Hits	139	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

LRP10_HUMAN
θ value	θ > 10 (rank : 842)	NC score	0.173708 (rank : 430)
Query Neighborhood Hits	671	Target Neighborhood Hits	197	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 843)	NC score	0.174401 (rank : 429)
Query Neighborhood Hits	671	Target Neighborhood Hits	169	Shared Neighborhood Hits	93
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP11_HUMAN
θ value	θ > 10 (rank : 844)	NC score	0.062708 (rank : 713)
Query Neighborhood Hits	671	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP11_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.065971 (rank : 703)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.177242 (rank : 420)
Query Neighborhood Hits	671	Target Neighborhood Hits	205	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 847)	NC score	0.175860 (rank : 425)
Query Neighborhood Hits	671	Target Neighborhood Hits	180	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.214865 (rank : 366)
Query Neighborhood Hits	671	Target Neighborhood Hits	280	Shared Neighborhood Hits	134
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

MCSP_HUMAN
θ value	θ > 10 (rank : 849)	NC score	0.068615 (rank : 691)
Query Neighborhood Hits	671	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEP1A_HUMAN
θ value	θ > 10 (rank : 850)	NC score	0.197378 (rank : 387)
Query Neighborhood Hits	671	Target Neighborhood Hits	162	Shared Neighborhood Hits	128
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 851)	NC score	0.201664 (rank : 382)
Query Neighborhood Hits	671	Target Neighborhood Hits	166	Shared Neighborhood Hits	130
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_HUMAN
θ value	θ > 10 (rank : 852)	NC score	0.094872 (rank : 584)
Query Neighborhood Hits	671	Target Neighborhood Hits	98	Shared Neighborhood Hits	60
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MFAP4_HUMAN
θ value	θ > 10 (rank : 853)	NC score	0.066209 (rank : 702)
Query Neighborhood Hits	671	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_MOUSE
θ value	θ > 10 (rank : 854)	NC score	0.066292 (rank : 701)
Query Neighborhood Hits	671	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFRP_HUMAN
θ value	θ > 10 (rank : 855)	NC score	0.117773 (rank : 522)
Query Neighborhood Hits	671	Target Neighborhood Hits	165	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 856)	NC score	0.105090 (rank : 552)
Query Neighborhood Hits	671	Target Neighborhood Hits	166	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NEO1_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.052250 (rank : 802)
Query Neighborhood Hits	671	Target Neighborhood Hits	530	Shared Neighborhood Hits	57
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	θ > 10 (rank : 858)	NC score	0.051693 (rank : 807)
Query Neighborhood Hits	671	Target Neighborhood Hits	523	Shared Neighborhood Hits	56
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NETO1_HUMAN
θ value	θ > 10 (rank : 859)	NC score	0.097337 (rank : 573)
Query Neighborhood Hits	671	Target Neighborhood Hits	110	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 860)	NC score	0.096866 (rank : 575)
Query Neighborhood Hits	671	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 861)	NC score	0.094230 (rank : 589)
Query Neighborhood Hits	671	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 862)	NC score	0.094255 (rank : 588)
Query Neighborhood Hits	671	Target Neighborhood Hits	113	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NEU1_MOUSE
θ value	θ > 10 (rank : 863)	NC score	0.075659 (rank : 656)
Query Neighborhood Hits	671	Target Neighborhood Hits	64	Shared Neighborhood Hits	54
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

NRP1_HUMAN
θ value	θ > 10 (rank : 864)	NC score	0.080144 (rank : 639)
Query Neighborhood Hits	671	Target Neighborhood Hits	119	Shared Neighborhood Hits	35
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 865)	NC score	0.079896 (rank : 640)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 866)	NC score	0.087444 (rank : 608)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	35
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 867)	NC score	0.084683 (rank : 622)
Query Neighborhood Hits	671	Target Neighborhood Hits	113	Shared Neighborhood Hits	34
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

ODFP_MOUSE
θ value	θ > 10 (rank : 868)	NC score	0.085636 (rank : 618)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	53
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PAP2_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.086334 (rank : 613)
Query Neighborhood Hits	671	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PCOC1_HUMAN
θ value	θ > 10 (rank : 870)	NC score	0.085135 (rank : 621)
Query Neighborhood Hits	671	Target Neighborhood Hits	146	Shared Neighborhood Hits	27
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 871)	NC score	0.087085 (rank : 609)
Query Neighborhood Hits	671	Target Neighborhood Hits	100	Shared Neighborhood Hits	27
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 872)	NC score	0.086376 (rank : 612)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 873)	NC score	0.085435 (rank : 619)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 874)	NC score	0.076892 (rank : 653)
Query Neighborhood Hits	671	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 875)	NC score	0.078744 (rank : 644)
Query Neighborhood Hits	671	Target Neighborhood Hits	72	Shared Neighborhood Hits	23
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PGH1_HUMAN
θ value	θ > 10 (rank : 876)	NC score	0.113635 (rank : 535)
Query Neighborhood Hits	671	Target Neighborhood Hits	91	Shared Neighborhood Hits	68
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_MOUSE
θ value	θ > 10 (rank : 877)	NC score	0.136712 (rank : 498)
Query Neighborhood Hits	671	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 878)	NC score	0.145650 (rank : 480)
Query Neighborhood Hits	671	Target Neighborhood Hits	103	Shared Neighborhood Hits	82
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 879)	NC score	0.158374 (rank : 454)
Query Neighborhood Hits	671	Target Neighborhood Hits	113	Shared Neighborhood Hits	93
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

RECK_MOUSE
θ value	θ > 10 (rank : 880)	NC score	0.183747 (rank : 405)
Query Neighborhood Hits	671	Target Neighborhood Hits	158	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

SDK1_HUMAN
θ value	θ > 10 (rank : 881)	NC score	0.053999 (rank : 788)
Query Neighborhood Hits	671	Target Neighborhood Hits	511	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
θ value	θ > 10 (rank : 882)	NC score	0.053966 (rank : 789)
Query Neighborhood Hits	671	Target Neighborhood Hits	495	Shared Neighborhood Hits	59
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_HUMAN
θ value	θ > 10 (rank : 883)	NC score	0.052817 (rank : 799)
Query Neighborhood Hits	671	Target Neighborhood Hits	495	Shared Neighborhood Hits	56
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK2_MOUSE
θ value	θ > 10 (rank : 884)	NC score	0.054812 (rank : 782)
Query Neighborhood Hits	671	Target Neighborhood Hits	480	Shared Neighborhood Hits	54
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SEZ6L_HUMAN
θ value	θ > 10 (rank : 885)	NC score	0.083266 (rank : 627)
Query Neighborhood Hits	671	Target Neighborhood Hits	289	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SHBG_HUMAN
θ value	θ > 10 (rank : 886)	NC score	0.142568 (rank : 485)
Query Neighborhood Hits	671	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 887)	NC score	0.136738 (rank : 497)
Query Neighborhood Hits	671	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SPIT1_HUMAN
θ value	θ > 10 (rank : 888)	NC score	0.072948 (rank : 673)
Query Neighborhood Hits	671	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPIT1_MOUSE
θ value	θ > 10 (rank : 889)	NC score	0.066652 (rank : 697)
Query Neighborhood Hits	671	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

SPON1_HUMAN
θ value	θ > 10 (rank : 890)	NC score	0.055662 (rank : 770)
Query Neighborhood Hits	671	Target Neighborhood Hits	117	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	θ > 10 (rank : 891)	NC score	0.058336 (rank : 744)
Query Neighborhood Hits	671	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SRPX_MOUSE
θ value	θ > 10 (rank : 892)	NC score	0.050603 (rank : 820)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

ST14_MOUSE
θ value	θ > 10 (rank : 893)	NC score	0.191010 (rank : 396)
Query Neighborhood Hits	671	Target Neighborhood Hits	419	Shared Neighborhood Hits	206
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

THRB_HUMAN
θ value	θ > 10 (rank : 894)	NC score	0.059232 (rank : 736)
Query Neighborhood Hits	671	Target Neighborhood Hits	196	Shared Neighborhood Hits	38
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 895)	NC score	0.057629 (rank : 751)
Query Neighborhood Hits	671	Target Neighborhood Hits	195	Shared Neighborhood Hits	38
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TMG1_HUMAN
θ value	θ > 10 (rank : 896)	NC score	0.086660 (rank : 611)
Query Neighborhood Hits	671	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

TMG2_HUMAN
θ value	θ > 10 (rank : 897)	NC score	0.066438 (rank : 700)
Query Neighborhood Hits	671	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

TMG2_MOUSE
θ value	θ > 10 (rank : 898)	NC score	0.065420 (rank : 706)
Query Neighborhood Hits	671	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

TMG3_HUMAN
θ value	θ > 10 (rank : 899)	NC score	0.078423 (rank : 646)
Query Neighborhood Hits	671	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG3_MOUSE
θ value	θ > 10 (rank : 900)	NC score	0.077495 (rank : 651)
Query Neighborhood Hits	671	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

TMG4_HUMAN
θ value	θ > 10 (rank : 901)	NC score	0.065939 (rank : 704)
Query Neighborhood Hits	671	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMG4_MOUSE
θ value	θ > 10 (rank : 902)	NC score	0.058849 (rank : 739)
Query Neighborhood Hits	671	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGN6, Q8BM25	Gene names	Prrg4, Tmg4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

TMPS2_HUMAN
θ value	θ > 10 (rank : 903)	NC score	0.050635 (rank : 818)
Query Neighborhood Hits	671	Target Neighborhood Hits	252	Shared Neighborhood Hits	59
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	θ > 10 (rank : 904)	NC score	0.053654 (rank : 790)
Query Neighborhood Hits	671	Target Neighborhood Hits	243	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_HUMAN
θ value	θ > 10 (rank : 905)	NC score	0.051365 (rank : 813)
Query Neighborhood Hits	671	Target Neighborhood Hits	245	Shared Neighborhood Hits	62
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
θ value	θ > 10 (rank : 906)	NC score	0.052014 (rank : 805)
Query Neighborhood Hits	671	Target Neighborhood Hits	239	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS7_HUMAN
θ value	θ > 10 (rank : 907)	NC score	0.095681 (rank : 581)
Query Neighborhood Hits	671	Target Neighborhood Hits	275	Shared Neighborhood Hits	93
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 908)	NC score	0.095055 (rank : 583)
Query Neighborhood Hits	671	Target Neighborhood Hits	275	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS9_HUMAN
θ value	θ > 10 (rank : 909)	NC score	0.058695 (rank : 742)
Query Neighborhood Hits	671	Target Neighborhood Hits	276	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	θ > 10 (rank : 910)	NC score	0.058329 (rank : 745)
Query Neighborhood Hits	671	Target Neighborhood Hits	296	Shared Neighborhood Hits	73
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TNR18_HUMAN
θ value	θ > 10 (rank : 911)	NC score	0.071097 (rank : 681)
Query Neighborhood Hits	671	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR19_MOUSE
θ value	θ > 10 (rank : 912)	NC score	0.092836 (rank : 595)
Query Neighborhood Hits	671	Target Neighborhood Hits	100	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1A_HUMAN
θ value	θ > 10 (rank : 913)	NC score	0.081454 (rank : 635)
Query Neighborhood Hits	671	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR1A_MOUSE
θ value	θ > 10 (rank : 914)	NC score	0.082373 (rank : 630)
Query Neighborhood Hits	671	Target Neighborhood Hits	131	Shared Neighborhood Hits	74
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR1B_HUMAN
θ value	θ > 10 (rank : 915)	NC score	0.079799 (rank : 642)
Query Neighborhood Hits	671	Target Neighborhood Hits	127	Shared Neighborhood Hits	71
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1B_MOUSE
θ value	θ > 10 (rank : 916)	NC score	0.057635 (rank : 750)
Query Neighborhood Hits	671	Target Neighborhood Hits	123	Shared Neighborhood Hits	62
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR22_MOUSE
θ value	θ > 10 (rank : 917)	NC score	0.119760 (rank : 520)
Query Neighborhood Hits	671	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
θ value	θ > 10 (rank : 918)	NC score	0.134152 (rank : 503)
Query Neighborhood Hits	671	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR5_HUMAN
θ value	θ > 10 (rank : 919)	NC score	0.090121 (rank : 602)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	75
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR6_HUMAN
θ value	θ > 10 (rank : 920)	NC score	0.081145 (rank : 636)
Query Neighborhood Hits	671	Target Neighborhood Hits	95	Shared Neighborhood Hits	64
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 921)	NC score	0.129112 (rank : 508)
Query Neighborhood Hits	671	Target Neighborhood Hits	208	Shared Neighborhood Hits	102
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_MOUSE
θ value	θ > 10 (rank : 922)	NC score	0.142166 (rank : 487)
Query Neighborhood Hits	671	Target Neighborhood Hits	137	Shared Neighborhood Hits	109
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TR10A_HUMAN
θ value	θ > 10 (rank : 923)	NC score	0.051121 (rank : 814)
Query Neighborhood Hits	671	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_MOUSE
θ value	θ > 10 (rank : 924)	NC score	0.060824 (rank : 724)
Query Neighborhood Hits	671	Target Neighborhood Hits	76	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR19L_HUMAN
θ value	θ > 10 (rank : 925)	NC score	0.072085 (rank : 677)
Query Neighborhood Hits	671	Target Neighborhood Hits	99	Shared Neighborhood Hits	51
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TSG6_HUMAN
θ value	θ > 10 (rank : 926)	NC score	0.106479 (rank : 550)
Query Neighborhood Hits	671	Target Neighborhood Hits	91	Shared Neighborhood Hits	35
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 927)	NC score	0.106040 (rank : 551)
Query Neighborhood Hits	671	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

VEGFC_MOUSE
θ value	θ > 10 (rank : 928)	NC score	0.152102 (rank : 463)
Query Neighborhood Hits	671	Target Neighborhood Hits	119	Shared Neighborhood Hits	98
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VITRN_HUMAN
θ value	θ > 10 (rank : 929)	NC score	0.074967 (rank : 662)
Query Neighborhood Hits	671	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

VITRN_MOUSE
θ value	θ > 10 (rank : 930)	NC score	0.075196 (rank : 660)
Query Neighborhood Hits	671	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

WFDC2_HUMAN
θ value	θ > 10 (rank : 931)	NC score	0.061189 (rank : 720)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	49
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

WISP3_HUMAN
θ value	θ > 10 (rank : 932)	NC score	0.050980 (rank : 815)
Query Neighborhood Hits	671	Target Neighborhood Hits	87	Shared Neighborhood Hits	50
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

Hits sorted by NC score

MEGF6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	671	Target Neighborhood Hits	671	Shared Neighborhood Hits	671
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

JAG1_HUMAN
NC score	0.899875 (rank : 2)	θ value	1.08223e-53 (rank : 32)
Query Neighborhood Hits	671	Target Neighborhood Hits	514	Shared Neighborhood Hits	433
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.899756 (rank : 3)	θ value	1.19655e-52 (rank : 33)
Query Neighborhood Hits	671	Target Neighborhood Hits	518	Shared Neighborhood Hits	428
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

FBN3_HUMAN
NC score	0.899381 (rank : 4)	θ value	2.73302e-81 (rank : 11)
Query Neighborhood Hits	671	Target Neighborhood Hits	543	Shared Neighborhood Hits	450
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

JAG2_HUMAN
NC score	0.899130 (rank : 5)	θ value	1.0458e-56 (rank : 23)
Query Neighborhood Hits	671	Target Neighborhood Hits	491	Shared Neighborhood Hits	428
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

FBN2_HUMAN
NC score	0.896225 (rank : 6)	θ value	3.34864e-71 (rank : 15)
Query Neighborhood Hits	671	Target Neighborhood Hits	560	Shared Neighborhood Hits	465
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.895648 (rank : 7)	θ value	7.98882e-65 (rank : 18)
Query Neighborhood Hits	671	Target Neighborhood Hits	563	Shared Neighborhood Hits	466
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LTBP4_MOUSE
NC score	0.895452 (rank : 8)	θ value	4.54686e-52 (rank : 36)
Query Neighborhood Hits	671	Target Neighborhood Hits	607	Shared Neighborhood Hits	410
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

FBN1_HUMAN
NC score	0.895216 (rank : 9)	θ value	3.13423e-69 (rank : 16)
Query Neighborhood Hits	671	Target Neighborhood Hits	557	Shared Neighborhood Hits	463
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
NC score	0.894370 (rank : 10)	θ value	2.56397e-71 (rank : 14)
Query Neighborhood Hits	671	Target Neighborhood Hits	549	Shared Neighborhood Hits	466
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

JAG2_MOUSE
NC score	0.893963 (rank : 11)	θ value	2.18062e-54 (rank : 30)
Query Neighborhood Hits	671	Target Neighborhood Hits	504	Shared Neighborhood Hits	426
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

SREC_HUMAN
NC score	0.888455 (rank : 12)	θ value	3.44927e-84 (rank : 10)
Query Neighborhood Hits	671	Target Neighborhood Hits	645	Shared Neighborhood Hits	456
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

DLL1_MOUSE
NC score	0.882177 (rank : 13)	θ value	9.8567e-31 (rank : 79)
Query Neighborhood Hits	671	Target Neighborhood Hits	456	Shared Neighborhood Hits	412
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

LTBP2_HUMAN
NC score	0.881304 (rank : 14)	θ value	8.57503e-51 (rank : 38)
Query Neighborhood Hits	671	Target Neighborhood Hits	552	Shared Neighborhood Hits	423
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
NC score	0.878949 (rank : 15)	θ value	4.40402e-47 (rank : 43)
Query Neighborhood Hits	671	Target Neighborhood Hits	617	Shared Neighborhood Hits	418
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

DLL1_HUMAN
NC score	0.877872 (rank : 16)	θ value	6.17384e-33 (rank : 65)
Query Neighborhood Hits	671	Target Neighborhood Hits	455	Shared Neighborhood Hits	404
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

SREC2_MOUSE
NC score	0.877217 (rank : 17)	θ value	1.18825e-76 (rank : 13)
Query Neighborhood Hits	671	Target Neighborhood Hits	605	Shared Neighborhood Hits	422
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CRUM2_HUMAN
NC score	0.873833 (rank : 18)	θ value	1.79631e-32 (rank : 69)
Query Neighborhood Hits	671	Target Neighborhood Hits	453	Shared Neighborhood Hits	400
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

LTBP3_HUMAN
NC score	0.871990 (rank : 19)	θ value	1.19655e-52 (rank : 34)
Query Neighborhood Hits	671	Target Neighborhood Hits	502	Shared Neighborhood Hits	403
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CRUM1_MOUSE
NC score	0.870817 (rank : 20)	θ value	8.06329e-33 (rank : 66)
Query Neighborhood Hits	671	Target Neighborhood Hits	444	Shared Neighborhood Hits	390
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

LTBP3_MOUSE
NC score	0.869863 (rank : 21)	θ value	8.02596e-49 (rank : 39)
Query Neighborhood Hits	671	Target Neighborhood Hits	475	Shared Neighborhood Hits	397
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

DLL4_HUMAN
NC score	0.868409 (rank : 22)	θ value	1.42001e-37 (rank : 58)
Query Neighborhood Hits	671	Target Neighborhood Hits	435	Shared Neighborhood Hits	382
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
NC score	0.868340 (rank : 23)	θ value	1.2049e-28 (rank : 84)
Query Neighborhood Hits	671	Target Neighborhood Hits	460	Shared Neighborhood Hits	385
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

CRUM1_HUMAN
NC score	0.867837 (rank : 24)	θ value	2.19075e-38 (rank : 56)
Query Neighborhood Hits	671	Target Neighborhood Hits	457	Shared Neighborhood Hits	398
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DLL4_MOUSE
NC score	0.867595 (rank : 25)	θ value	1.08726e-37 (rank : 57)
Query Neighborhood Hits	671	Target Neighborhood Hits	440	Shared Neighborhood Hits	390
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_MOUSE
NC score	0.865254 (rank : 26)	θ value	3.87602e-27 (rank : 91)
Query Neighborhood Hits	671	Target Neighborhood Hits	413	Shared Neighborhood Hits	365
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

SREC2_HUMAN
NC score	0.865088 (rank : 27)	θ value	9.0981e-77 (rank : 12)
Query Neighborhood Hits	671	Target Neighborhood Hits	645	Shared Neighborhood Hits	420
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LTB1L_HUMAN
NC score	0.860445 (rank : 28)	θ value	4.39379e-55 (rank : 26)
Query Neighborhood Hits	671	Target Neighborhood Hits	553	Shared Neighborhood Hits	399
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DLK_HUMAN
NC score	0.860421 (rank : 29)	θ value	1.5773e-20 (rank : 117)
Query Neighborhood Hits	671	Target Neighborhood Hits	401	Shared Neighborhood Hits	367
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

LTB1S_HUMAN
NC score	0.859187 (rank : 30)	θ value	4.39379e-55 (rank : 27)
Query Neighborhood Hits	671	Target Neighborhood Hits	502	Shared Neighborhood Hits	394
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NOTC1_MOUSE
NC score	0.858295 (rank : 31)	θ value	1.18275e-92 (rank : 6)
Query Neighborhood Hits	671	Target Neighborhood Hits	916	Shared Neighborhood Hits	477
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NELL1_HUMAN
NC score	0.857348 (rank : 32)	θ value	6.84181e-24 (rank : 105)
Query Neighborhood Hits	671	Target Neighborhood Hits	451	Shared Neighborhood Hits	390
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

LTB1L_MOUSE
NC score	0.856703 (rank : 33)	θ value	1.66964e-54 (rank : 28)
Query Neighborhood Hits	671	Target Neighborhood Hits	514	Shared Neighborhood Hits	404
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.856119 (rank : 34)	θ value	1.66964e-54 (rank : 29)
Query Neighborhood Hits	671	Target Neighborhood Hits	479	Shared Neighborhood Hits	389
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NELL2_MOUSE
NC score	0.854746 (rank : 35)	θ value	3.62785e-25 (rank : 100)
Query Neighborhood Hits	671	Target Neighborhood Hits	436	Shared Neighborhood Hits	394
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NELL2_HUMAN
NC score	0.854250 (rank : 36)	θ value	1.12775e-26 (rank : 93)
Query Neighborhood Hits	671	Target Neighborhood Hits	449	Shared Neighborhood Hits	395
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

DLK_MOUSE
NC score	0.852148 (rank : 37)	θ value	8.65492e-19 (rank : 128)
Query Neighborhood Hits	671	Target Neighborhood Hits	374	Shared Neighborhood Hits	349
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

SCUB3_MOUSE
NC score	0.851346 (rank : 38)	θ value	1.27544e-62 (rank : 22)
Query Neighborhood Hits	671	Target Neighborhood Hits	442	Shared Neighborhood Hits	349
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.850300 (rank : 39)	θ value	5.7252e-63 (rank : 21)
Query Neighborhood Hits	671	Target Neighborhood Hits	428	Shared Neighborhood Hits	343
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

FBLN2_HUMAN
NC score	0.849201 (rank : 40)	θ value	2.3352e-48 (rank : 41)
Query Neighborhood Hits	671	Target Neighborhood Hits	392	Shared Neighborhood Hits	306
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

DLL3_HUMAN
NC score	0.848684 (rank : 41)	θ value	2.12685e-25 (rank : 99)
Query Neighborhood Hits	671	Target Neighborhood Hits	419	Shared Neighborhood Hits	372
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

EGFL9_HUMAN
NC score	0.847999 (rank : 42)	θ value	2.20094e-22 (rank : 114)
Query Neighborhood Hits	671	Target Neighborhood Hits	365	Shared Neighborhood Hits	342
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
NC score	0.846212 (rank : 43)	θ value	2.59989e-23 (rank : 109)
Query Neighborhood Hits	671	Target Neighborhood Hits	379	Shared Neighborhood Hits	347
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

DLL3_MOUSE
NC score	0.841974 (rank : 44)	θ value	9.87957e-23 (rank : 113)
Query Neighborhood Hits	671	Target Neighborhood Hits	399	Shared Neighborhood Hits	354
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

FBLN2_MOUSE
NC score	0.841765 (rank : 45)	θ value	4.40402e-47 (rank : 42)
Query Neighborhood Hits	671	Target Neighborhood Hits	505	Shared Neighborhood Hits	329
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

NOTC3_HUMAN
NC score	0.837476 (rank : 46)	θ value	6.06035e-97 (rank : 3)
Query Neighborhood Hits	671	Target Neighborhood Hits	1062	Shared Neighborhood Hits	505
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
NC score	0.836228 (rank : 47)	θ value	1.03374e-96 (rank : 4)
Query Neighborhood Hits	671	Target Neighborhood Hits	975	Shared Neighborhood Hits	486
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.835520 (rank : 48)	θ value	3.22093e-90 (rank : 7)
Query Neighborhood Hits	671	Target Neighborhood Hits	906	Shared Neighborhood Hits	467
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FBLN1_MOUSE
NC score	0.833151 (rank : 49)	θ value	2.041e-52 (rank : 35)
Query Neighborhood Hits	671	Target Neighborhood Hits	329	Shared Neighborhood Hits	308
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

NOTC2_MOUSE
NC score	0.829493 (rank : 50)	θ value	1.06727e-101 (rank : 2)
Query Neighborhood Hits	671	Target Neighborhood Hits	1069	Shared Neighborhood Hits	467
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FBLN1_HUMAN
NC score	0.828942 (rank : 51)	θ value	4.85792e-54 (rank : 31)
Query Neighborhood Hits	671	Target Neighborhood Hits	324	Shared Neighborhood Hits	308
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

NOTC2_HUMAN
NC score	0.827389 (rank : 52)	θ value	3.1125e-93 (rank : 5)
Query Neighborhood Hits	671	Target Neighborhood Hits	1113	Shared Neighborhood Hits	487
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

C1QR1_HUMAN
NC score	0.826107 (rank : 53)	θ value	1.24399e-33 (rank : 62)
Query Neighborhood Hits	671	Target Neighborhood Hits	493	Shared Neighborhood Hits	330
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

TRBM_HUMAN
NC score	0.822252 (rank : 54)	θ value	7.54701e-31 (rank : 78)
Query Neighborhood Hits	671	Target Neighborhood Hits	339	Shared Neighborhood Hits	300
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

C1QR1_MOUSE
NC score	0.821271 (rank : 55)	θ value	2.26708e-35 (rank : 59)
Query Neighborhood Hits	671	Target Neighborhood Hits	342	Shared Neighborhood Hits	303
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

NOTC4_HUMAN
NC score	0.818515 (rank : 56)	θ value	4.65103e-89 (rank : 8)
Query Neighborhood Hits	671	Target Neighborhood Hits	905	Shared Neighborhood Hits	491
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
NC score	0.817997 (rank : 57)	θ value	5.14231e-88 (rank : 9)
Query Neighborhood Hits	671	Target Neighborhood Hits	872	Shared Neighborhood Hits	481
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

STAB2_HUMAN
NC score	0.814949 (rank : 58)	θ value	1.16704e-23 (rank : 108)
Query Neighborhood Hits	671	Target Neighborhood Hits	534	Shared Neighborhood Hits	423
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB1_MOUSE
NC score	0.814259 (rank : 59)	θ value	1.42661e-21 (rank : 115)
Query Neighborhood Hits	671	Target Neighborhood Hits	566	Shared Neighborhood Hits	446
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB1_HUMAN
NC score	0.814241 (rank : 60)	θ value	7.56453e-23 (rank : 112)
Query Neighborhood Hits	671	Target Neighborhood Hits	546	Shared Neighborhood Hits	431
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

FBLN5_HUMAN
NC score	0.813634 (rank : 61)	θ value	1.6774e-38 (rank : 55)
Query Neighborhood Hits	671	Target Neighborhood Hits	329	Shared Neighborhood Hits	308
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

GAS6_HUMAN
NC score	0.811310 (rank : 62)	θ value	3.87602e-27 (rank : 92)
Query Neighborhood Hits	671	Target Neighborhood Hits	348	Shared Neighborhood Hits	316
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

TRBM_MOUSE
NC score	0.809946 (rank : 63)	θ value	8.91499e-32 (rank : 75)
Query Neighborhood Hits	671	Target Neighborhood Hits	361	Shared Neighborhood Hits	313
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

FBLN5_MOUSE
NC score	0.809226 (rank : 64)	θ value	4.41421e-39 (rank : 53)
Query Neighborhood Hits	671	Target Neighborhood Hits	317	Shared Neighborhood Hits	295
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

STAB2_MOUSE
NC score	0.808266 (rank : 65)	θ value	5.79196e-23 (rank : 111)
Query Neighborhood Hits	671	Target Neighborhood Hits	528	Shared Neighborhood Hits	425
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CREL1_HUMAN
NC score	0.807953 (rank : 66)	θ value	3.29651e-10 (rank : 191)
Query Neighborhood Hits	671	Target Neighborhood Hits	441	Shared Neighborhood Hits	303
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

GAS6_MOUSE
NC score	0.806476 (rank : 67)	θ value	7.30988e-26 (rank : 95)
Query Neighborhood Hits	671	Target Neighborhood Hits	343	Shared Neighborhood Hits	314
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN4_HUMAN
NC score	0.805562 (rank : 68)	θ value	3.06405e-32 (rank : 70)
Query Neighborhood Hits	671	Target Neighborhood Hits	278	Shared Neighborhood Hits	265
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

WIF1_HUMAN
NC score	0.803294 (rank : 69)	θ value	4.29542e-18 (rank : 135)
Query Neighborhood Hits	671	Target Neighborhood Hits	392	Shared Neighborhood Hits	363
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
NC score	0.803200 (rank : 70)	θ value	1.02238e-19 (rank : 122)
Query Neighborhood Hits	671	Target Neighborhood Hits	393	Shared Neighborhood Hits	367
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

PROS_HUMAN
NC score	0.802160 (rank : 71)	θ value	1.16704e-23 (rank : 106)
Query Neighborhood Hits	671	Target Neighborhood Hits	340	Shared Neighborhood Hits	312
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FBLN4_MOUSE
NC score	0.798872 (rank : 72)	θ value	6.82597e-32 (rank : 73)
Query Neighborhood Hits	671	Target Neighborhood Hits	270	Shared Neighborhood Hits	259
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

PROS_MOUSE
NC score	0.796988 (rank : 73)	θ value	1.16704e-23 (rank : 107)
Query Neighborhood Hits	671	Target Neighborhood Hits	330	Shared Neighborhood Hits	302
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

CREL1_MOUSE
NC score	0.795995 (rank : 74)	θ value	1.74796e-11 (rank : 180)
Query Neighborhood Hits	671	Target Neighborhood Hits	524	Shared Neighborhood Hits	318
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

FBLN3_HUMAN
NC score	0.792044 (rank : 75)	θ value	1.16434e-31 (rank : 76)
Query Neighborhood Hits	671	Target Neighborhood Hits	293	Shared Neighborhood Hits	276
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
NC score	0.781829 (rank : 76)	θ value	6.82597e-32 (rank : 72)
Query Neighborhood Hits	671	Target Neighborhood Hits	279	Shared Neighborhood Hits	263
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

MEGF8_HUMAN
NC score	0.780789 (rank : 77)	θ value	1.47631e-18 (rank : 131)
Query Neighborhood Hits	671	Target Neighborhood Hits	528	Shared Neighborhood Hits	380
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
NC score	0.773214 (rank : 78)	θ value	2.06002e-20 (rank : 118)
Query Neighborhood Hits	671	Target Neighborhood Hits	520	Shared Neighborhood Hits	372
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

EGFL7_HUMAN
NC score	0.771782 (rank : 79)	θ value	1.63604e-09 (rank : 201)
Query Neighborhood Hits	671	Target Neighborhood Hits	325	Shared Neighborhood Hits	305
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

MATN2_HUMAN
NC score	0.770539 (rank : 80)	θ value	5.7252e-63 (rank : 20)
Query Neighborhood Hits	671	Target Neighborhood Hits	365	Shared Neighborhood Hits	281
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

EGF_MOUSE
NC score	0.765105 (rank : 81)	θ value	4.57862e-28 (rank : 87)
Query Neighborhood Hits	671	Target Neighborhood Hits	358	Shared Neighborhood Hits	326
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

MATN2_MOUSE
NC score	0.761163 (rank : 82)	θ value	2.32439e-64 (rank : 19)
Query Neighborhood Hits	671	Target Neighborhood Hits	356	Shared Neighborhood Hits	278
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

NID2_HUMAN
NC score	0.750008 (rank : 83)	θ value	2.69047e-20 (rank : 119)
Query Neighborhood Hits	671	Target Neighborhood Hits	456	Shared Neighborhood Hits	304
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

CUBN_MOUSE
NC score	0.744735 (rank : 84)	θ value	1.80048e-24 (rank : 104)
Query Neighborhood Hits	671	Target Neighborhood Hits	477	Shared Neighborhood Hits	362
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUBN_HUMAN
NC score	0.742931 (rank : 85)	θ value	2.12685e-25 (rank : 98)
Query Neighborhood Hits	671	Target Neighborhood Hits	482	Shared Neighborhood Hits	371
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

NID2_MOUSE
NC score	0.741095 (rank : 86)	θ value	4.58923e-20 (rank : 120)
Query Neighborhood Hits	671	Target Neighborhood Hits	338	Shared Neighborhood Hits	287
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

EGFL7_MOUSE
NC score	0.736508 (rank : 87)	θ value	2.36244e-08 (rank : 223)
Query Neighborhood Hits	671	Target Neighborhood Hits	287	Shared Neighborhood Hits	278
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

NID1_MOUSE
NC score	0.736382 (rank : 88)	θ value	1.38178e-16 (rank : 150)
Query Neighborhood Hits	671	Target Neighborhood Hits	335	Shared Neighborhood Hits	280
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_HUMAN
NC score	0.735894 (rank : 89)	θ value	1.63225e-17 (rank : 142)
Query Neighborhood Hits	671	Target Neighborhood Hits	329	Shared Neighborhood Hits	289
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

EGF_HUMAN
NC score	0.731325 (rank : 90)	θ value	1.73987e-27 (rank : 89)
Query Neighborhood Hits	671	Target Neighborhood Hits	343	Shared Neighborhood Hits	309
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

UROM_HUMAN
NC score	0.731124 (rank : 91)	θ value	1.16975e-15 (rank : 158)
Query Neighborhood Hits	671	Target Neighborhood Hits	284	Shared Neighborhood Hits	260
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

LAMA5_MOUSE
NC score	0.727666 (rank : 92)	θ value	1.36902e-48 (rank : 40)
Query Neighborhood Hits	671	Target Neighborhood Hits	828	Shared Neighborhood Hits	417
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LRP1_HUMAN
NC score	0.720214 (rank : 93)	θ value	1.99529e-15 (rank : 159)
Query Neighborhood Hits	671	Target Neighborhood Hits	617	Shared Neighborhood Hits	461
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

AGRIN_HUMAN
NC score	0.718347 (rank : 94)	θ value	2.27234e-27 (rank : 90)
Query Neighborhood Hits	671	Target Neighborhood Hits	582	Shared Neighborhood Hits	402
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

UROM_MOUSE
NC score	0.716309 (rank : 95)	θ value	3.89403e-11 (rank : 181)
Query Neighborhood Hits	671	Target Neighborhood Hits	276	Shared Neighborhood Hits	255
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

KRA53_HUMAN
NC score	0.714814 (rank : 96)	θ value	3.40345e-15 (rank : 162)
Query Neighborhood Hits	671	Target Neighborhood Hits	331	Shared Neighborhood Hits	272
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA51_HUMAN
NC score	0.714521 (rank : 97)	θ value	2.0648e-12 (rank : 175)
Query Neighborhood Hits	671	Target Neighborhood Hits	288	Shared Neighborhood Hits	225
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LAMA5_HUMAN
NC score	0.713771 (rank : 98)	θ value	2.25659e-51 (rank : 37)
Query Neighborhood Hits	671	Target Neighborhood Hits	976	Shared Neighborhood Hits	419
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MEGF9_HUMAN
NC score	0.713180 (rank : 99)	θ value	1.13037e-18 (rank : 129)
Query Neighborhood Hits	671	Target Neighborhood Hits	557	Shared Neighborhood Hits	318
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SUSD1_HUMAN
NC score	0.711277 (rank : 100)	θ value	8.67504e-11 (rank : 184)
Query Neighborhood Hits	671	Target Neighborhood Hits	285	Shared Neighborhood Hits	225
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

LRP1B_HUMAN
NC score	0.711074 (rank : 101)	θ value	4.02038e-16 (rank : 151)
Query Neighborhood Hits	671	Target Neighborhood Hits	602	Shared Neighborhood Hits	450
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EGFL8_HUMAN
NC score	0.710658 (rank : 102)	θ value	4.76016e-09 (rank : 212)
Query Neighborhood Hits	671	Target Neighborhood Hits	270	Shared Neighborhood Hits	256
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

LRP1B_MOUSE
NC score	0.709263 (rank : 103)	θ value	8.10077e-17 (rank : 147)
Query Neighborhood Hits	671	Target Neighborhood Hits	606	Shared Neighborhood Hits	448
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EGFL8_MOUSE
NC score	0.707958 (rank : 104)	θ value	5.08577e-11 (rank : 182)
Query Neighborhood Hits	671	Target Neighborhood Hits	266	Shared Neighborhood Hits	260
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

LAMB2_HUMAN
NC score	0.697754 (rank : 105)	θ value	4.2656e-42 (rank : 46)
Query Neighborhood Hits	671	Target Neighborhood Hits	692	Shared Neighborhood Hits	340
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

TENA_HUMAN
NC score	0.697041 (rank : 106)	θ value	6.77864e-56 (rank : 25)
Query Neighborhood Hits	671	Target Neighborhood Hits	631	Shared Neighborhood Hits	399
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LAMB2_MOUSE
NC score	0.691056 (rank : 107)	θ value	9.50281e-42 (rank : 47)
Query Neighborhood Hits	671	Target Neighborhood Hits	722	Shared Neighborhood Hits	338
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

TENA_MOUSE
NC score	0.690672 (rank : 108)	θ value	5.19021e-56 (rank : 24)
Query Neighborhood Hits	671	Target Neighborhood Hits	596	Shared Neighborhood Hits	380
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENX_HUMAN
NC score	0.689300 (rank : 109)	θ value	2.24614e-67 (rank : 17)
Query Neighborhood Hits	671	Target Neighborhood Hits	789	Shared Neighborhood Hits	426
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LAMA1_MOUSE
NC score	0.684641 (rank : 110)	θ value	4.41421e-39 (rank : 54)
Query Neighborhood Hits	671	Target Neighborhood Hits	838	Shared Neighborhood Hits	388
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_HUMAN
NC score	0.680970 (rank : 111)	θ value	1.3722e-40 (rank : 50)
Query Neighborhood Hits	671	Target Neighborhood Hits	804	Shared Neighborhood Hits	373
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

EMR1_HUMAN
NC score	0.680278 (rank : 112)	θ value	5.79196e-23 (rank : 110)
Query Neighborhood Hits	671	Target Neighborhood Hits	382	Shared Neighborhood Hits	281
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

LAMC3_MOUSE
NC score	0.679668 (rank : 113)	θ value	3.06405e-32 (rank : 71)
Query Neighborhood Hits	671	Target Neighborhood Hits	624	Shared Neighborhood Hits	336
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

KRA58_HUMAN
NC score	0.676581 (rank : 114)	θ value	8.97725e-08 (rank : 231)
Query Neighborhood Hits	671	Target Neighborhood Hits	324	Shared Neighborhood Hits	260
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMC3_HUMAN
NC score	0.675471 (rank : 115)	θ value	9.52487e-34 (rank : 61)
Query Neighborhood Hits	671	Target Neighborhood Hits	588	Shared Neighborhood Hits	352
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEGF9_MOUSE
NC score	0.672170 (rank : 116)	θ value	3.63628e-17 (rank : 144)
Query Neighborhood Hits	671	Target Neighborhood Hits	896	Shared Neighborhood Hits	300
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ZAN_MOUSE
NC score	0.672076 (rank : 117)	θ value	1.0531e-32 (rank : 68)
Query Neighborhood Hits	671	Target Neighborhood Hits	808	Shared Neighborhood Hits	475
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CD248_MOUSE
NC score	0.667027 (rank : 118)	θ value	1.47631e-18 (rank : 130)
Query Neighborhood Hits	671	Target Neighborhood Hits	578	Shared Neighborhood Hits	237
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MATN4_HUMAN
NC score	0.666117 (rank : 119)	θ value	1.9192e-34 (rank : 60)
Query Neighborhood Hits	671	Target Neighborhood Hits	287	Shared Neighborhood Hits	242
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

LRP2_HUMAN
NC score	0.661378 (rank : 120)	θ value	1.16975e-15 (rank : 156)
Query Neighborhood Hits	671	Target Neighborhood Hits	573	Shared Neighborhood Hits	444
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

NAGPA_HUMAN
NC score	0.661030 (rank : 121)	θ value	4.74913e-17 (rank : 145)
Query Neighborhood Hits	671	Target Neighborhood Hits	282	Shared Neighborhood Hits	264
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

MATN3_MOUSE
NC score	0.659801 (rank : 122)	θ value	3.17079e-29 (rank : 82)
Query Neighborhood Hits	671	Target Neighborhood Hits	261	Shared Neighborhood Hits	221
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

NAGPA_MOUSE
NC score	0.659688 (rank : 123)	θ value	8.10077e-17 (rank : 148)
Query Neighborhood Hits	671	Target Neighborhood Hits	308	Shared Neighborhood Hits	288
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

MATN3_HUMAN
NC score	0.659636 (rank : 124)	θ value	1.28732e-30 (rank : 80)
Query Neighborhood Hits	671	Target Neighborhood Hits	268	Shared Neighborhood Hits	218
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

EMR2_HUMAN
NC score	0.659531 (rank : 125)	θ value	1.37858e-24 (rank : 103)
Query Neighborhood Hits	671	Target Neighborhood Hits	345	Shared Neighborhood Hits	263
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

CD248_HUMAN
NC score	0.659058 (rank : 126)	θ value	5.99374e-20 (rank : 121)
Query Neighborhood Hits	671	Target Neighborhood Hits	679	Shared Neighborhood Hits	253
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TSP4_MOUSE
NC score	0.654830 (rank : 127)	θ value	1.99992e-07 (rank : 243)
Query Neighborhood Hits	671	Target Neighborhood Hits	276	Shared Neighborhood Hits	255
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

CD97_HUMAN
NC score	0.651199 (rank : 128)	θ value	6.18819e-25 (rank : 102)
Query Neighborhood Hits	671	Target Neighborhood Hits	353	Shared Neighborhood Hits	266
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

TSP4_HUMAN
NC score	0.646780 (rank : 129)	θ value	1.17247e-07 (rank : 235)
Query Neighborhood Hits	671	Target Neighborhood Hits	277	Shared Neighborhood Hits	253
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

LAMC2_MOUSE
NC score	0.646077 (rank : 130)	θ value	1.058e-16 (rank : 149)
Query Neighborhood Hits	671	Target Neighborhood Hits	614	Shared Neighborhood Hits	327
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

COMP_MOUSE
NC score	0.644185 (rank : 131)	θ value	6.87365e-08 (rank : 226)
Query Neighborhood Hits	671	Target Neighborhood Hits	290	Shared Neighborhood Hits	260
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

LDLR_HUMAN
NC score	0.643986 (rank : 132)	θ value	5.07402e-19 (rank : 126)
Query Neighborhood Hits	671	Target Neighborhood Hits	375	Shared Neighborhood Hits	318
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

EMR1_MOUSE
NC score	0.641559 (rank : 133)	θ value	1.2049e-28 (rank : 85)
Query Neighborhood Hits	671	Target Neighborhood Hits	349	Shared Neighborhood Hits	261
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

KRA59_HUMAN
NC score	0.641072 (rank : 134)	θ value	6.87365e-08 (rank : 228)
Query Neighborhood Hits	671	Target Neighborhood Hits	310	Shared Neighborhood Hits	236
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMB1_MOUSE
NC score	0.640755 (rank : 135)	θ value	2.34062e-40 (rank : 51)
Query Neighborhood Hits	671	Target Neighborhood Hits	919	Shared Neighborhood Hits	325
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MATN4_MOUSE
NC score	0.640004 (rank : 136)	θ value	1.0531e-32 (rank : 67)
Query Neighborhood Hits	671	Target Neighborhood Hits	277	Shared Neighborhood Hits	232
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

LAMA2_HUMAN
NC score	0.634191 (rank : 137)	θ value	1.41672e-45 (rank : 44)
Query Neighborhood Hits	671	Target Neighborhood Hits	1092	Shared Neighborhood Hits	377
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

VLDLR_HUMAN
NC score	0.633750 (rank : 138)	θ value	5.60996e-18 (rank : 138)
Query Neighborhood Hits	671	Target Neighborhood Hits	383	Shared Neighborhood Hits	308
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

KR107_HUMAN
NC score	0.633703 (rank : 139)	θ value	1.9326e-10 (rank : 187)
Query Neighborhood Hits	671	Target Neighborhood Hits	330	Shared Neighborhood Hits	264
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

LAMB3_MOUSE
NC score	0.632540 (rank : 140)	θ value	1.62847e-25 (rank : 97)
Query Neighborhood Hits	671	Target Neighborhood Hits	444	Shared Neighborhood Hits	248
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

VLDLR_MOUSE
NC score	0.631884 (rank : 141)	θ value	7.32683e-18 (rank : 139)
Query Neighborhood Hits	671	Target Neighborhood Hits	360	Shared Neighborhood Hits	296
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

KRA57_HUMAN
NC score	0.631248 (rank : 142)	θ value	8.97725e-08 (rank : 230)
Query Neighborhood Hits	671	Target Neighborhood Hits	269	Shared Neighborhood Hits	222
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

LAMC1_MOUSE
NC score	0.629147 (rank : 143)	θ value	3.61944e-33 (rank : 64)
Query Neighborhood Hits	671	Target Neighborhood Hits	856	Shared Neighborhood Hits	333
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LRP8_MOUSE
NC score	0.628324 (rank : 144)	θ value	9.56915e-18 (rank : 140)
Query Neighborhood Hits	671	Target Neighborhood Hits	385	Shared Neighborhood Hits	303
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

KR106_HUMAN
NC score	0.627386 (rank : 145)	θ value	8.67504e-11 (rank : 183)
Query Neighborhood Hits	671	Target Neighborhood Hits	347	Shared Neighborhood Hits	281
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR104_HUMAN
NC score	0.625878 (rank : 146)	θ value	2.13673e-09 (rank : 203)
Query Neighborhood Hits	671	Target Neighborhood Hits	313	Shared Neighborhood Hits	245
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KRA55_HUMAN
NC score	0.621215 (rank : 147)	θ value	3.64472e-09 (rank : 210)
Query Neighborhood Hits	671	Target Neighborhood Hits	257	Shared Neighborhood Hits	203
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LAMB1_HUMAN
NC score	0.620515 (rank : 148)	θ value	2.58786e-39 (rank : 52)
Query Neighborhood Hits	671	Target Neighborhood Hits	1018	Shared Neighborhood Hits	341
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

COMP_HUMAN
NC score	0.620220 (rank : 149)	θ value	1.99992e-07 (rank : 239)
Query Neighborhood Hits	671	Target Neighborhood Hits	258	Shared Neighborhood Hits	238
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

LDLR_MOUSE
NC score	0.619757 (rank : 150)	θ value	4.29542e-18 (rank : 134)
Query Neighborhood Hits	671	Target Neighborhood Hits	382	Shared Neighborhood Hits	310
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

KRA54_HUMAN
NC score	0.617937 (rank : 151)	θ value	2.52405e-10 (rank : 189)
Query Neighborhood Hits	671	Target Neighborhood Hits	270	Shared Neighborhood Hits	211
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LAMC2_HUMAN
NC score	0.614134 (rank : 152)	θ value	1.63225e-17 (rank : 141)
Query Neighborhood Hits	671	Target Neighborhood Hits	715	Shared Neighborhood Hits	315
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

SLIT1_MOUSE
NC score	0.613379 (rank : 153)	θ value	4.74913e-17 (rank : 146)
Query Neighborhood Hits	671	Target Neighborhood Hits	715	Shared Neighborhood Hits	385
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT1_HUMAN
NC score	0.611711 (rank : 154)	θ value	5.60996e-18 (rank : 137)
Query Neighborhood Hits	671	Target Neighborhood Hits	700	Shared Neighborhood Hits	375
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

LAMC1_HUMAN
NC score	0.610800 (rank : 155)	θ value	2.42779e-29 (rank : 81)
Query Neighborhood Hits	671	Target Neighborhood Hits	922	Shared Neighborhood Hits	343
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NTNG2_MOUSE
NC score	0.607045 (rank : 156)	θ value	8.11959e-09 (rank : 216)
Query Neighborhood Hits	671	Target Neighborhood Hits	276	Shared Neighborhood Hits	260
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LRP8_HUMAN
NC score	0.606808 (rank : 157)	θ value	2.27762e-19 (rank : 123)
Query Neighborhood Hits	671	Target Neighborhood Hits	346	Shared Neighborhood Hits	273
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LAMA3_MOUSE
NC score	0.605444 (rank : 158)	θ value	2.51237e-26 (rank : 94)
Query Neighborhood Hits	671	Target Neighborhood Hits	859	Shared Neighborhood Hits	373
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

USH2A_MOUSE
NC score	0.601552 (rank : 159)	θ value	8.04462e-41 (rank : 49)
Query Neighborhood Hits	671	Target Neighborhood Hits	626	Shared Neighborhood Hits	336
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LAMA2_MOUSE
NC score	0.601272 (rank : 160)	θ value	2.95404e-43 (rank : 45)
Query Neighborhood Hits	671	Target Neighborhood Hits	1198	Shared Neighborhood Hits	377
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NTNG2_HUMAN
NC score	0.599503 (rank : 161)	θ value	1.133e-10 (rank : 186)
Query Neighborhood Hits	671	Target Neighborhood Hits	276	Shared Neighborhood Hits	253
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

EDIL3_MOUSE
NC score	0.598934 (rank : 162)	θ value	9.59137e-10 (rank : 198)
Query Neighborhood Hits	671	Target Neighborhood Hits	317	Shared Neighborhood Hits	277
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LAMB3_HUMAN
NC score	0.598350 (rank : 163)	θ value	7.30988e-26 (rank : 96)
Query Neighborhood Hits	671	Target Neighborhood Hits	461	Shared Neighborhood Hits	221
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

TSP3_MOUSE
NC score	0.596152 (rank : 164)	θ value	1.99992e-07 (rank : 242)
Query Neighborhood Hits	671	Target Neighborhood Hits	247	Shared Neighborhood Hits	221
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

SLIT2_HUMAN
NC score	0.595369 (rank : 165)	θ value	5.25075e-16 (rank : 153)
Query Neighborhood Hits	671	Target Neighborhood Hits	708	Shared Neighborhood Hits	379
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LRP4_MOUSE
NC score	0.589426 (rank : 166)	θ value	2.97466e-19 (rank : 124)
Query Neighborhood Hits	671	Target Neighborhood Hits	351	Shared Neighborhood Hits	285
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

TSP3_HUMAN
NC score	0.589072 (rank : 167)	θ value	1.53129e-07 (rank : 238)
Query Neighborhood Hits	671	Target Neighborhood Hits	250	Shared Neighborhood Hits	217
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

SLIT2_MOUSE
NC score	0.587911 (rank : 168)	θ value	1.99529e-15 (rank : 160)
Query Neighborhood Hits	671	Target Neighborhood Hits	684	Shared Neighborhood Hits	358
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LRP4_HUMAN
NC score	0.584817 (rank : 169)	θ value	3.28887e-18 (rank : 132)
Query Neighborhood Hits	671	Target Neighborhood Hits	355	Shared Neighborhood Hits	291
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

GRN_MOUSE
NC score	0.584034 (rank : 170)	θ value	3.52202e-12 (rank : 177)
Query Neighborhood Hits	671	Target Neighborhood Hits	248	Shared Neighborhood Hits	231
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

EDIL3_HUMAN
NC score	0.583317 (rank : 171)	θ value	1.17247e-07 (rank : 233)
Query Neighborhood Hits	671	Target Neighborhood Hits	292	Shared Neighborhood Hits	253
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

GRN_HUMAN
NC score	0.582254 (rank : 172)	θ value	8.38298e-14 (rank : 167)
Query Neighborhood Hits	671	Target Neighborhood Hits	268	Shared Neighborhood Hits	233
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

SLIT3_MOUSE
NC score	0.582130 (rank : 173)	θ value	5.07402e-19 (rank : 127)
Query Neighborhood Hits	671	Target Neighborhood Hits	700	Shared Neighborhood Hits	369
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SLIT3_HUMAN
NC score	0.573173 (rank : 174)	θ value	2.97466e-19 (rank : 125)
Query Neighborhood Hits	671	Target Neighborhood Hits	682	Shared Neighborhood Hits	357
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

HHIP_HUMAN
NC score	0.571266 (rank : 175)	θ value	6.87365e-08 (rank : 227)
Query Neighborhood Hits	671	Target Neighborhood Hits	249	Shared Neighborhood Hits	236
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

NTNG1_HUMAN
NC score	0.571021 (rank : 176)	θ value	4.76016e-09 (rank : 213)
Query Neighborhood Hits	671	Target Neighborhood Hits	247	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PROZ_MOUSE
NC score	0.570495 (rank : 177)	θ value	1.17247e-07 (rank : 234)
Query Neighborhood Hits	671	Target Neighborhood Hits	410	Shared Neighborhood Hits	263
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

NTNG1_MOUSE
NC score	0.570295 (rank : 178)	θ value	8.97725e-08 (rank : 232)
Query Neighborhood Hits	671	Target Neighborhood Hits	246	Shared Neighborhood Hits	224
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

USH2A_HUMAN
NC score	0.569891 (rank : 179)	θ value	1.6247e-33 (rank : 63)
Query Neighborhood Hits	671	Target Neighborhood Hits	600	Shared Neighborhood Hits	305
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

PCSK5_MOUSE
NC score	0.566816 (rank : 180)	θ value	1.33217e-27 (rank : 88)
Query Neighborhood Hits	671	Target Neighborhood Hits	613	Shared Neighborhood Hits	402
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

KR511_HUMAN
NC score	0.564957 (rank : 181)	θ value	9.92553e-07 (rank : 256)
Query Neighborhood Hits	671	Target Neighborhood Hits	231	Shared Neighborhood Hits	181
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA52_HUMAN
NC score	0.563216 (rank : 182)	θ value	3.08544e-08 (rank : 225)
Query Neighborhood Hits	671	Target Neighborhood Hits	236	Shared Neighborhood Hits	196
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

ITB6_MOUSE
NC score	0.562775 (rank : 183)	θ value	1.06045e-08 (rank : 217)
Query Neighborhood Hits	671	Target Neighborhood Hits	341	Shared Neighborhood Hits	297
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

PROZ_HUMAN
NC score	0.561309 (rank : 184)	θ value	4.76016e-09 (rank : 214)
Query Neighborhood Hits	671	Target Neighborhood Hits	422	Shared Neighborhood Hits	270
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CD97_MOUSE
NC score	0.560500 (rank : 185)	θ value	2.7842e-17 (rank : 143)
Query Neighborhood Hits	671	Target Neighborhood Hits	295	Shared Neighborhood Hits	221
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

ITB5_MOUSE
NC score	0.553233 (rank : 186)	θ value	3.29651e-10 (rank : 192)
Query Neighborhood Hits	671	Target Neighborhood Hits	329	Shared Neighborhood Hits	303
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

KRA56_HUMAN
NC score	0.552412 (rank : 187)	θ value	7.1131e-05 (rank : 294)
Query Neighborhood Hits	671	Target Neighborhood Hits	207	Shared Neighborhood Hits	173
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KR171_HUMAN
NC score	0.549739 (rank : 188)	θ value	0.00134147 (rank : 324)
Query Neighborhood Hits	671	Target Neighborhood Hits	144	Shared Neighborhood Hits	122
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

HHIP_MOUSE
NC score	0.547601 (rank : 189)	θ value	1.29631e-06 (rank : 258)
Query Neighborhood Hits	671	Target Neighborhood Hits	219	Shared Neighborhood Hits	204
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ELTD1_MOUSE
NC score	0.544917 (rank : 190)	θ value	4.59992e-12 (rank : 178)
Query Neighborhood Hits	671	Target Neighborhood Hits	288	Shared Neighborhood Hits	213
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

ITB6_HUMAN
NC score	0.539634 (rank : 191)	θ value	2.79066e-09 (rank : 205)
Query Neighborhood Hits	671	Target Neighborhood Hits	318	Shared Neighborhood Hits	285
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

CRIM1_HUMAN
NC score	0.538340 (rank : 192)	θ value	3.41135e-07 (rank : 247)
Query Neighborhood Hits	671	Target Neighborhood Hits	362	Shared Neighborhood Hits	283
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ITB3_HUMAN
NC score	0.536873 (rank : 193)	θ value	2.13673e-09 (rank : 202)
Query Neighborhood Hits	671	Target Neighborhood Hits	325	Shared Neighborhood Hits	297
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KR101_HUMAN
NC score	0.536370 (rank : 194)	θ value	3.41135e-07 (rank : 248)
Query Neighborhood Hits	671	Target Neighborhood Hits	261	Shared Neighborhood Hits	211
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

ITB5_HUMAN
NC score	0.536109 (rank : 195)	θ value	7.34386e-10 (rank : 197)
Query Neighborhood Hits	671	Target Neighborhood Hits	310	Shared Neighborhood Hits	283
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

LAMA4_MOUSE
NC score	0.533938 (rank : 196)	θ value	1.68911e-14 (rank : 166)
Query Neighborhood Hits	671	Target Neighborhood Hits	584	Shared Neighborhood Hits	229
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA3_HUMAN
NC score	0.527148 (rank : 197)	θ value	1.9326e-10 (rank : 188)
Query Neighborhood Hits	671	Target Neighborhood Hits	760	Shared Neighborhood Hits	284
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

KR510_HUMAN
NC score	0.526043 (rank : 198)	θ value	1.69304e-06 (rank : 263)
Query Neighborhood Hits	671	Target Neighborhood Hits	217	Shared Neighborhood Hits	169
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

ITB2_MOUSE
NC score	0.524837 (rank : 199)	θ value	1.25267e-09 (rank : 199)
Query Neighborhood Hits	671	Target Neighborhood Hits	326	Shared Neighborhood Hits	298
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

FRAS1_HUMAN
NC score	0.524567 (rank : 200)	θ value	9.24701e-21 (rank : 116)
Query Neighborhood Hits	671	Target Neighborhood Hits	759	Shared Neighborhood Hits	390
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ITB7_HUMAN
NC score	0.522040 (rank : 201)	θ value	3.64472e-09 (rank : 209)
Query Neighborhood Hits	671	Target Neighborhood Hits	290	Shared Neighborhood Hits	267
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
NC score	0.516859 (rank : 202)	θ value	2.79066e-09 (rank : 206)
Query Neighborhood Hits	671	Target Neighborhood Hits	277	Shared Neighborhood Hits	257
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB3_MOUSE
NC score	0.514030 (rank : 203)	θ value	7.34386e-10 (rank : 196)
Query Neighborhood Hits	671	Target Neighborhood Hits	319	Shared Neighborhood Hits	289
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ATRN_MOUSE
NC score	0.507811 (rank : 204)	θ value	4.92598e-06 (rank : 271)
Query Neighborhood Hits	671	Target Neighborhood Hits	519	Shared Neighborhood Hits	302
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

KR102_HUMAN
NC score	0.505745 (rank : 205)	θ value	7.1131e-05 (rank : 293)
Query Neighborhood Hits	671	Target Neighborhood Hits	264	Shared Neighborhood Hits	214
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

ATRN_HUMAN
NC score	0.505731 (rank : 206)	θ value	4.45536e-07 (rank : 249)
Query Neighborhood Hits	671	Target Neighborhood Hits	525	Shared Neighborhood Hits	301
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

FRAS1_MOUSE
NC score	0.503546 (rank : 207)	θ value	4.73814e-25 (rank : 101)
Query Neighborhood Hits	671	Target Neighborhood Hits	747	Shared Neighborhood Hits	383
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA4_HUMAN
NC score	0.502090 (rank : 208)	θ value	2.43908e-13 (rank : 168)
Query Neighborhood Hits	671	Target Neighborhood Hits	708	Shared Neighborhood Hits	224
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KR105_HUMAN
NC score	0.501918 (rank : 209)	θ value	5.62301e-10 (rank : 194)
Query Neighborhood Hits	671	Target Neighborhood Hits	271	Shared Neighborhood Hits	220
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

HMCN1_HUMAN
NC score	0.501498 (rank : 210)	θ value	1.2411e-41 (rank : 48)
Query Neighborhood Hits	671	Target Neighborhood Hits	983	Shared Neighborhood Hits	359
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ITB2_HUMAN
NC score	0.500656 (rank : 211)	θ value	7.34386e-10 (rank : 195)
Query Neighborhood Hits	671	Target Neighborhood Hits	282	Shared Neighborhood Hits	255
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

PGBM_MOUSE
NC score	0.500283 (rank : 212)	θ value	5.8054e-15 (rank : 163)
Query Neighborhood Hits	671	Target Neighborhood Hits	1073	Shared Neighborhood Hits	416
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SSPO_MOUSE
NC score	0.491507 (rank : 213)	θ value	8.95645e-16 (rank : 155)
Query Neighborhood Hits	671	Target Neighborhood Hits	800	Shared Neighborhood Hits	445
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

PGBM_HUMAN
NC score	0.490666 (rank : 214)	θ value	1.16975e-15 (rank : 157)
Query Neighborhood Hits	671	Target Neighborhood Hits	1113	Shared Neighborhood Hits	411
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ITB1_MOUSE
NC score	0.484746 (rank : 215)	θ value	4.45536e-07 (rank : 250)
Query Neighborhood Hits	671	Target Neighborhood Hits	283	Shared Neighborhood Hits	250
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

TSP1_MOUSE
NC score	0.484407 (rank : 216)	θ value	1.80886e-08 (rank : 222)
Query Neighborhood Hits	671	Target Neighborhood Hits	396	Shared Neighborhood Hits	291
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

NET4_HUMAN
NC score	0.483819 (rank : 217)	θ value	6.21693e-09 (rank : 215)
Query Neighborhood Hits	671	Target Neighborhood Hits	191	Shared Neighborhood Hits	167
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

ITB1_HUMAN
NC score	0.483495 (rank : 218)	θ value	1.29631e-06 (rank : 259)
Query Neighborhood Hits	671	Target Neighborhood Hits	298	Shared Neighborhood Hits	261
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB4_HUMAN
NC score	0.481770 (rank : 219)	θ value	2.0648e-12 (rank : 174)
Query Neighborhood Hits	671	Target Neighborhood Hits	458	Shared Neighborhood Hits	274
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

TSP1_HUMAN
NC score	0.481179 (rank : 220)	θ value	1.06045e-08 (rank : 218)
Query Neighborhood Hits	671	Target Neighborhood Hits	389	Shared Neighborhood Hits	283
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TENR_MOUSE
NC score	0.480785 (rank : 221)	θ value	6.85773e-16 (rank : 154)
Query Neighborhood Hits	671	Target Neighborhood Hits	531	Shared Neighborhood Hits	323
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

NET4_MOUSE
NC score	0.479076 (rank : 222)	θ value	2.79066e-09 (rank : 208)
Query Neighborhood Hits	671	Target Neighborhood Hits	180	Shared Neighborhood Hits	165
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

TENR_HUMAN
NC score	0.472925 (rank : 223)	θ value	4.02038e-16 (rank : 152)
Query Neighborhood Hits	671	Target Neighborhood Hits	526	Shared Neighborhood Hits	322
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

CSPG2_MOUSE
NC score	0.470387 (rank : 224)	θ value	2.88788e-06 (rank : 266)
Query Neighborhood Hits	671	Target Neighborhood Hits	711	Shared Neighborhood Hits	271
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

KR10B_HUMAN
NC score	0.467164 (rank : 225)	θ value	3.77169e-06 (rank : 268)
Query Neighborhood Hits	671	Target Neighborhood Hits	269	Shared Neighborhood Hits	215
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

NET2_MOUSE
NC score	0.466552 (rank : 226)	θ value	0.000121331 (rank : 305)
Query Neighborhood Hits	671	Target Neighborhood Hits	193	Shared Neighborhood Hits	167
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET2_HUMAN
NC score	0.466171 (rank : 227)	θ value	0.000158464 (rank : 307)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	161
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

CSPG2_HUMAN
NC score	0.464941 (rank : 228)	θ value	1.43324e-05 (rank : 278)
Query Neighborhood Hits	671	Target Neighborhood Hits	681	Shared Neighborhood Hits	271
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG3_MOUSE
NC score	0.461902 (rank : 229)	θ value	2.61198e-07 (rank : 244)
Query Neighborhood Hits	671	Target Neighborhood Hits	657	Shared Neighborhood Hits	273
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

KR109_HUMAN
NC score	0.458139 (rank : 230)	θ value	9.29e-05 (rank : 298)
Query Neighborhood Hits	671	Target Neighborhood Hits	226	Shared Neighborhood Hits	184
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR108_HUMAN
NC score	0.456345 (rank : 231)	θ value	0.00035302 (rank : 313)
Query Neighborhood Hits	671	Target Neighborhood Hits	226	Shared Neighborhood Hits	180
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR10C_HUMAN
NC score	0.455260 (rank : 232)	θ value	0.00020696 (rank : 309)
Query Neighborhood Hits	671	Target Neighborhood Hits	219	Shared Neighborhood Hits	182
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

CSPG3_HUMAN
NC score	0.451087 (rank : 233)	θ value	1.43324e-05 (rank : 279)
Query Neighborhood Hits	671	Target Neighborhood Hits	676	Shared Neighborhood Hits	259
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ITB8_HUMAN
NC score	0.436613 (rank : 234)	θ value	3.08544e-08 (rank : 224)
Query Neighborhood Hits	671	Target Neighborhood Hits	280	Shared Neighborhood Hits	249
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

SORL_MOUSE
NC score	0.428051 (rank : 235)	θ value	4.92598e-06 (rank : 274)
Query Neighborhood Hits	671	Target Neighborhood Hits	439	Shared Neighborhood Hits	261
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TSP2_HUMAN
NC score	0.425301 (rank : 236)	θ value	0.00175202 (rank : 332)
Query Neighborhood Hits	671	Target Neighborhood Hits	359	Shared Neighborhood Hits	271
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

NET1_HUMAN
NC score	0.421213 (rank : 237)	θ value	0.00298849 (rank : 338)
Query Neighborhood Hits	671	Target Neighborhood Hits	149	Shared Neighborhood Hits	127
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

TSP2_MOUSE
NC score	0.420296 (rank : 238)	θ value	0.000270298 (rank : 310)
Query Neighborhood Hits	671	Target Neighborhood Hits	352	Shared Neighborhood Hits	263
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

FATH_HUMAN
NC score	0.419561 (rank : 239)	θ value	4.30538e-10 (rank : 193)
Query Neighborhood Hits	671	Target Neighborhood Hits	570	Shared Neighborhood Hits	328
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

NET1_MOUSE
NC score	0.417493 (rank : 240)	θ value	0.00298849 (rank : 339)
Query Neighborhood Hits	671	Target Neighborhood Hits	151	Shared Neighborhood Hits	126
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

SORL_HUMAN
NC score	0.415299 (rank : 241)	θ value	7.1131e-05 (rank : 296)
Query Neighborhood Hits	671	Target Neighborhood Hits	440	Shared Neighborhood Hits	251
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

LYAM3_MOUSE
NC score	0.411544 (rank : 242)	θ value	2.79066e-09 (rank : 207)
Query Neighborhood Hits	671	Target Neighborhood Hits	390	Shared Neighborhood Hits	260
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CELR2_HUMAN
NC score	0.410471 (rank : 243)	θ value	2.60593e-15 (rank : 161)
Query Neighborhood Hits	671	Target Neighborhood Hits	657	Shared Neighborhood Hits	368
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

TENN_MOUSE
NC score	0.408759 (rank : 244)	θ value	4.16044e-13 (rank : 169)
Query Neighborhood Hits	671	Target Neighborhood Hits	484	Shared Neighborhood Hits	290
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CELR3_HUMAN
NC score	0.404642 (rank : 245)	θ value	5.60996e-18 (rank : 136)
Query Neighborhood Hits	671	Target Neighborhood Hits	680	Shared Neighborhood Hits	343
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
NC score	0.402068 (rank : 246)	θ value	4.29542e-18 (rank : 133)
Query Neighborhood Hits	671	Target Neighborhood Hits	687	Shared Neighborhood Hits	349
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

KRA13_HUMAN
NC score	0.401723 (rank : 247)	θ value	0.00175202 (rank : 329)
Query Neighborhood Hits	671	Target Neighborhood Hits	144	Shared Neighborhood Hits	119
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

CFC1_HUMAN
NC score	0.401536 (rank : 248)	θ value	0.00665767 (rank : 350)
Query Neighborhood Hits	671	Target Neighborhood Hits	148	Shared Neighborhood Hits	145
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

MFGM_MOUSE
NC score	0.399244 (rank : 249)	θ value	2.13673e-09 (rank : 204)
Query Neighborhood Hits	671	Target Neighborhood Hits	233	Shared Neighborhood Hits	199
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

KRA94_HUMAN
NC score	0.399068 (rank : 250)	θ value	0.0961366 (rank : 413)
Query Neighborhood Hits	671	Target Neighborhood Hits	204	Shared Neighborhood Hits	175
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

ELTD1_HUMAN
NC score	0.398911 (rank : 251)	θ value	0.000121331 (rank : 303)
Query Neighborhood Hits	671	Target Neighborhood Hits	269	Shared Neighborhood Hits	189
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

KRA93_HUMAN
NC score	0.397120 (rank : 252)	θ value	0.0431538 (rank : 393)
Query Neighborhood Hits	671	Target Neighborhood Hits	203	Shared Neighborhood Hits	164
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA98_HUMAN
NC score	0.396064 (rank : 253)	θ value	0.0193708 (rank : 375)
Query Neighborhood Hits	671	Target Neighborhood Hits	185	Shared Neighborhood Hits	153
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

TENN_HUMAN
NC score	0.395704 (rank : 254)	θ value	2.0648e-12 (rank : 176)
Query Neighborhood Hits	671	Target Neighborhood Hits	453	Shared Neighborhood Hits	281
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

KRA47_HUMAN
NC score	0.395116 (rank : 255)	θ value	0.00869519 (rank : 358)
Query Neighborhood Hits	671	Target Neighborhood Hits	204	Shared Neighborhood Hits	157
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

CELR1_MOUSE
NC score	0.394923 (rank : 256)	θ value	7.58209e-15 (rank : 164)
Query Neighborhood Hits	671	Target Neighborhood Hits	617	Shared Neighborhood Hits	318
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

NFX1_HUMAN
NC score	0.394271 (rank : 257)	θ value	1.87187e-05 (rank : 286)
Query Neighborhood Hits	671	Target Neighborhood Hits	405	Shared Neighborhood Hits	200
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

CELR1_HUMAN
NC score	0.392156 (rank : 258)	θ value	1.29331e-14 (rank : 165)
Query Neighborhood Hits	671	Target Neighborhood Hits	613	Shared Neighborhood Hits	313
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

KRA45_HUMAN
NC score	0.392089 (rank : 259)	θ value	0.0563607 (rank : 396)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	160
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KR10A_HUMAN
NC score	0.388331 (rank : 260)	θ value	0.000158464 (rank : 306)
Query Neighborhood Hits	671	Target Neighborhood Hits	232	Shared Neighborhood Hits	190
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

LYAM2_MOUSE
NC score	0.384420 (rank : 261)	θ value	9.29e-05 (rank : 300)
Query Neighborhood Hits	671	Target Neighborhood Hits	420	Shared Neighborhood Hits	281
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KRA92_HUMAN
NC score	0.381222 (rank : 262)	θ value	0.00102713 (rank : 319)
Query Neighborhood Hits	671	Target Neighborhood Hits	198	Shared Neighborhood Hits	160
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA11_HUMAN
NC score	0.380262 (rank : 263)	θ value	0.0252991 (rank : 380)
Query Neighborhood Hits	671	Target Neighborhood Hits	155	Shared Neighborhood Hits	131
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

ZAN_HUMAN
NC score	0.378981 (rank : 264)	θ value	1.43324e-05 (rank : 282)
Query Neighborhood Hits	671	Target Neighborhood Hits	679	Shared Neighborhood Hits	322
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

LCE1B_HUMAN
NC score	0.377263 (rank : 265)	θ value	0.00665767 (rank : 353)
Query Neighborhood Hits	671	Target Neighborhood Hits	58	Shared Neighborhood Hits	52
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

TDGF1_MOUSE
NC score	0.376470 (rank : 266)	θ value	0.00175202 (rank : 331)
Query Neighborhood Hits	671	Target Neighborhood Hits	146	Shared Neighborhood Hits	144
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

LYAM2_HUMAN
NC score	0.375095 (rank : 267)	θ value	2.61198e-07 (rank : 245)
Query Neighborhood Hits	671	Target Neighborhood Hits	394	Shared Neighborhood Hits	258
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KR103_HUMAN
NC score	0.372968 (rank : 268)	θ value	0.000786445 (rank : 317)
Query Neighborhood Hits	671	Target Neighborhood Hits	212	Shared Neighborhood Hits	178
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

VWF_HUMAN
NC score	0.372935 (rank : 269)	θ value	7.59969e-07 (rank : 255)
Query Neighborhood Hits	671	Target Neighborhood Hits	396	Shared Neighborhood Hits	281
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CELR2_MOUSE
NC score	0.372261 (rank : 270)	θ value	5.43371e-13 (rank : 170)
Query Neighborhood Hits	671	Target Neighborhood Hits	584	Shared Neighborhood Hits	310
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

LCE1C_HUMAN
NC score	0.372159 (rank : 271)	θ value	0.0113563 (rank : 363)
Query Neighborhood Hits	671	Target Neighborhood Hits	65	Shared Neighborhood Hits	56
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

KRA44_HUMAN
NC score	0.370819 (rank : 272)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	671	Target Neighborhood Hits	162	Shared Neighborhood Hits	130
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KR414_HUMAN
NC score	0.370319 (rank : 273)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	671	Target Neighborhood Hits	199	Shared Neighborhood Hits	156
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

LYAM3_HUMAN
NC score	0.368822 (rank : 274)	θ value	1.25267e-09 (rank : 200)
Query Neighborhood Hits	671	Target Neighborhood Hits	378	Shared Neighborhood Hits	245
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CFC1_MOUSE
NC score	0.363491 (rank : 275)	θ value	0.365318 (rank : 461)
Query Neighborhood Hits	671	Target Neighborhood Hits	125	Shared Neighborhood Hits	124
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

MUC5B_HUMAN
NC score	0.358880 (rank : 276)	θ value	4.1701e-05 (rank : 290)
Query Neighborhood Hits	671	Target Neighborhood Hits	1020	Shared Neighborhood Hits	319
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

KRA99_HUMAN
NC score	0.357952 (rank : 277)	θ value	0.0193708 (rank : 376)
Query Neighborhood Hits	671	Target Neighborhood Hits	173	Shared Neighborhood Hits	141
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

KR412_HUMAN
NC score	0.354932 (rank : 278)	θ value	0.0961366 (rank : 412)
Query Neighborhood Hits	671	Target Neighborhood Hits	178	Shared Neighborhood Hits	143
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

CRAC1_MOUSE
NC score	0.354302 (rank : 279)	θ value	0.0252991 (rank : 379)
Query Neighborhood Hits	671	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_HUMAN
NC score	0.352963 (rank : 280)	θ value	0.0330416 (rank : 386)
Query Neighborhood Hits	671	Target Neighborhood Hits	111	Shared Neighborhood Hits	98
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

PERT_HUMAN
NC score	0.346129 (rank : 281)	θ value	1.29631e-06 (rank : 260)
Query Neighborhood Hits	671	Target Neighborhood Hits	221	Shared Neighborhood Hits	166
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

BMP1_MOUSE
NC score	0.343921 (rank : 282)	θ value	9.26847e-13 (rank : 173)
Query Neighborhood Hits	671	Target Neighborhood Hits	236	Shared Neighborhood Hits	180
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

VWF_MOUSE
NC score	0.342544 (rank : 283)	θ value	5.81887e-07 (rank : 252)
Query Neighborhood Hits	671	Target Neighborhood Hits	381	Shared Neighborhood Hits	268
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

BMP1_HUMAN
NC score	0.342105 (rank : 284)	θ value	9.26847e-13 (rank : 172)
Query Neighborhood Hits	671	Target Neighborhood Hits	233	Shared Neighborhood Hits	179
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_MOUSE
NC score	0.340662 (rank : 285)	θ value	5.43371e-13 (rank : 171)
Query Neighborhood Hits	671	Target Neighborhood Hits	237	Shared Neighborhood Hits	178
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

HABP2_HUMAN
NC score	0.338534 (rank : 286)	θ value	8.97725e-08 (rank : 229)
Query Neighborhood Hits	671	Target Neighborhood Hits	431	Shared Neighborhood Hits	262
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LRP6_HUMAN
NC score	0.335193 (rank : 287)	θ value	6.43352e-06 (rank : 275)
Query Neighborhood Hits	671	Target Neighborhood Hits	235	Shared Neighborhood Hits	173
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

EMR3_HUMAN
NC score	0.334560 (rank : 288)	θ value	0.00298849 (rank : 337)
Query Neighborhood Hits	671	Target Neighborhood Hits	245	Shared Neighborhood Hits	161
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

TLL2_HUMAN
NC score	0.334081 (rank : 289)	θ value	4.59992e-12 (rank : 179)
Query Neighborhood Hits	671	Target Neighborhood Hits	241	Shared Neighborhood Hits	180
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CLC14_MOUSE
NC score	0.333608 (rank : 290)	θ value	0.0113563 (rank : 362)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	113
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

TLL1_HUMAN
NC score	0.333224 (rank : 291)	θ value	2.52405e-10 (rank : 190)
Query Neighborhood Hits	671	Target Neighborhood Hits	236	Shared Neighborhood Hits	174
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

HABP2_MOUSE
NC score	0.332484 (rank : 292)	θ value	4.1701e-05 (rank : 289)
Query Neighborhood Hits	671	Target Neighborhood Hits	445	Shared Neighborhood Hits	276
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

KRA15_HUMAN
NC score	0.331130 (rank : 293)	θ value	0.0736092 (rank : 404)
Query Neighborhood Hits	671	Target Neighborhood Hits	126	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

LRP6_MOUSE
NC score	0.330900 (rank : 294)	θ value	1.09739e-05 (rank : 276)
Query Neighborhood Hits	671	Target Neighborhood Hits	232	Shared Neighborhood Hits	172
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

TLL2_MOUSE
NC score	0.329157 (rank : 295)	θ value	8.67504e-11 (rank : 185)
Query Neighborhood Hits	671	Target Neighborhood Hits	240	Shared Neighborhood Hits	178
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

FA10_MOUSE
NC score	0.327868 (rank : 296)	θ value	1.99992e-07 (rank : 240)
Query Neighborhood Hits	671	Target Neighborhood Hits	435	Shared Neighborhood Hits	271
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_HUMAN
NC score	0.324987 (rank : 297)	θ value	7.59969e-07 (rank : 253)
Query Neighborhood Hits	671	Target Neighborhood Hits	431	Shared Neighborhood Hits	263
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

LCE1D_HUMAN
NC score	0.324461 (rank : 298)	θ value	0.365318 (rank : 467)
Query Neighborhood Hits	671	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
NC score	0.324370 (rank : 299)	θ value	0.0148317 (rank : 370)
Query Neighborhood Hits	671	Target Neighborhood Hits	53	Shared Neighborhood Hits	45
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

TDGF1_HUMAN
NC score	0.322223 (rank : 300)	θ value	0.00390308 (rank : 346)
Query Neighborhood Hits	671	Target Neighborhood Hits	132	Shared Neighborhood Hits	131
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

LRP5_MOUSE
NC score	0.320453 (rank : 301)	θ value	7.1131e-05 (rank : 295)
Query Neighborhood Hits	671	Target Neighborhood Hits	236	Shared Neighborhood Hits	168
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

PROC_MOUSE
NC score	0.319736 (rank : 302)	θ value	3.64472e-09 (rank : 211)
Query Neighborhood Hits	671	Target Neighborhood Hits	426	Shared Neighborhood Hits	272
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PERT_MOUSE
NC score	0.319219 (rank : 303)	θ value	0.00102713 (rank : 320)
Query Neighborhood Hits	671	Target Neighborhood Hits	221	Shared Neighborhood Hits	160
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

TDGF2_HUMAN
NC score	0.318896 (rank : 304)	θ value	0.00298849 (rank : 340)
Query Neighborhood Hits	671	Target Neighborhood Hits	131	Shared Neighborhood Hits	127
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

LCE1F_HUMAN
NC score	0.317141 (rank : 305)	θ value	0.0113563 (rank : 364)
Query Neighborhood Hits	671	Target Neighborhood Hits	48	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

CLC14_HUMAN
NC score	0.317028 (rank : 306)	θ value	0.0330416 (rank : 384)
Query Neighborhood Hits	671	Target Neighborhood Hits	143	Shared Neighborhood Hits	115
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

PCSK5_HUMAN
NC score	0.315535 (rank : 307)	θ value	9.29e-05 (rank : 301)
Query Neighborhood Hits	671	Target Neighborhood Hits	291	Shared Neighborhood Hits	230
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

LRP5_HUMAN
NC score	0.314915 (rank : 308)	θ value	9.29e-05 (rank : 299)
Query Neighborhood Hits	671	Target Neighborhood Hits	224	Shared Neighborhood Hits	161
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

MATN1_HUMAN
NC score	0.311727 (rank : 309)	θ value	4.92598e-06 (rank : 272)
Query Neighborhood Hits	671	Target Neighborhood Hits	191	Shared Neighborhood Hits	143
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
NC score	0.310725 (rank : 310)	θ value	4.92598e-06 (rank : 273)
Query Neighborhood Hits	671	Target Neighborhood Hits	186	Shared Neighborhood Hits	139
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

FA9_HUMAN
NC score	0.307910 (rank : 311)	θ value	1.80886e-08 (rank : 220)
Query Neighborhood Hits	671	Target Neighborhood Hits	421	Shared Neighborhood Hits	257
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

LYAM1_MOUSE
NC score	0.306624 (rank : 312)	θ value	0.00869519 (rank : 359)
Query Neighborhood Hits	671	Target Neighborhood Hits	332	Shared Neighborhood Hits	201
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

TEFF2_MOUSE
NC score	0.304925 (rank : 313)	θ value	0.000602161 (rank : 316)
Query Neighborhood Hits	671	Target Neighborhood Hits	214	Shared Neighborhood Hits	155
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.301751 (rank : 314)	θ value	0.00102713 (rank : 321)
Query Neighborhood Hits	671	Target Neighborhood Hits	211	Shared Neighborhood Hits	152
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

UROL1_MOUSE
NC score	0.299911 (rank : 315)	θ value	2.36792 (rank : 560)
Query Neighborhood Hits	671	Target Neighborhood Hits	235	Shared Neighborhood Hits	151
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

LYAM1_HUMAN
NC score	0.299479 (rank : 316)	θ value	0.0736092 (rank : 405)
Query Neighborhood Hits	671	Target Neighborhood Hits	315	Shared Neighborhood Hits	200
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LCE1A_HUMAN
NC score	0.293356 (rank : 317)	θ value	0.62314 (rank : 486)
Query Neighborhood Hits	671	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

ESM1_HUMAN
NC score	0.291849 (rank : 318)	θ value	0.000121331 (rank : 304)
Query Neighborhood Hits	671	Target Neighborhood Hits	110	Shared Neighborhood Hits	100
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

LCE3A_HUMAN
NC score	0.291484 (rank : 319)	θ value	0.125558 (rank : 418)
Query Neighborhood Hits	671	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

KR410_HUMAN
NC score	0.291224 (rank : 320)	θ value	0.00665767 (rank : 352)
Query Neighborhood Hits	671	Target Neighborhood Hits	156	Shared Neighborhood Hits	127
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

FA7_HUMAN
NC score	0.289411 (rank : 321)	θ value	2.88788e-06 (rank : 267)
Query Neighborhood Hits	671	Target Neighborhood Hits	404	Shared Neighborhood Hits	242
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

PROC_HUMAN
NC score	0.289010 (rank : 322)	θ value	1.80886e-08 (rank : 221)
Query Neighborhood Hits	671	Target Neighborhood Hits	406	Shared Neighborhood Hits	254
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

MUC13_MOUSE
NC score	0.288356 (rank : 323)	θ value	0.0961366 (rank : 414)
Query Neighborhood Hits	671	Target Neighborhood Hits	447	Shared Neighborhood Hits	173
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PHXR5_MOUSE
NC score	0.286028 (rank : 324)	θ value	0.00665767 (rank : 354)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	77
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

UROL1_HUMAN
NC score	0.285497 (rank : 325)	θ value	0.813845 (rank : 502)
Query Neighborhood Hits	671	Target Neighborhood Hits	213	Shared Neighborhood Hits	141
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

TECTA_MOUSE
NC score	0.280899 (rank : 326)	θ value	0.00665767 (rank : 356)
Query Neighborhood Hits	671	Target Neighborhood Hits	244	Shared Neighborhood Hits	207
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

KRA42_HUMAN
NC score	0.274881 (rank : 327)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	671	Target Neighborhood Hits	149	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

PCSK6_HUMAN
NC score	0.269721 (rank : 328)	θ value	9.92553e-07 (rank : 257)
Query Neighborhood Hits	671	Target Neighborhood Hits	298	Shared Neighborhood Hits	189
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

HGFA_HUMAN
NC score	0.261767 (rank : 329)	θ value	5.81887e-07 (rank : 251)
Query Neighborhood Hits	671	Target Neighborhood Hits	436	Shared Neighborhood Hits	234
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

TECTA_HUMAN
NC score	0.260796 (rank : 330)	θ value	0.000786445 (rank : 318)
Query Neighborhood Hits	671	Target Neighborhood Hits	239	Shared Neighborhood Hits	198
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TIE1_HUMAN
NC score	0.259226 (rank : 331)	θ value	6.82597e-32 (rank : 74)
Query Neighborhood Hits	671	Target Neighborhood Hits	1241	Shared Neighborhood Hits	330
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

HGFA_MOUSE
NC score	0.258913 (rank : 332)	θ value	1.99992e-07 (rank : 241)
Query Neighborhood Hits	671	Target Neighborhood Hits	419	Shared Neighborhood Hits	238
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

BMPER_MOUSE
NC score	0.258239 (rank : 333)	θ value	0.365318 (rank : 460)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

MT3_MOUSE
NC score	0.255871 (rank : 334)	θ value	1.38821 (rank : 521)
Query Neighborhood Hits	671	Target Neighborhood Hits	68	Shared Neighborhood Hits	62
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

NRX1A_HUMAN
NC score	0.254427 (rank : 335)	θ value	3.0926 (rank : 568)
Query Neighborhood Hits	671	Target Neighborhood Hits	170	Shared Neighborhood Hits	128
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

RELN_MOUSE
NC score	0.254420 (rank : 336)	θ value	0.0113563 (rank : 367)
Query Neighborhood Hits	671	Target Neighborhood Hits	235	Shared Neighborhood Hits	191
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

TIE1_MOUSE
NC score	0.253996 (rank : 337)	θ value	5.77852e-31 (rank : 77)
Query Neighborhood Hits	671	Target Neighborhood Hits	1266	Shared Neighborhood Hits	329
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

NRX1A_MOUSE
NC score	0.252960 (rank : 338)	θ value	3.0926 (rank : 569)
Query Neighborhood Hits	671	Target Neighborhood Hits	164	Shared Neighborhood Hits	127
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

ESM1_MOUSE
NC score	0.252158 (rank : 339)	θ value	1.53129e-07 (rank : 236)
Query Neighborhood Hits	671	Target Neighborhood Hits	107	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FAT2_HUMAN
NC score	0.249228 (rank : 340)	θ value	2.21117e-06 (rank : 265)
Query Neighborhood Hits	671	Target Neighborhood Hits	507	Shared Neighborhood Hits	230
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

RELN_HUMAN
NC score	0.245693 (rank : 341)	θ value	0.0113563 (rank : 366)
Query Neighborhood Hits	671	Target Neighborhood Hits	233	Shared Neighborhood Hits	188
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

FA7_MOUSE
NC score	0.243269 (rank : 342)	θ value	2.44474e-05 (rank : 288)
Query Neighborhood Hits	671	Target Neighborhood Hits	374	Shared Neighborhood Hits	215
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

PGCB_MOUSE
NC score	0.242687 (rank : 343)	θ value	2.36792 (rank : 554)
Query Neighborhood Hits	671	Target Neighborhood Hits	459	Shared Neighborhood Hits	190
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

EMR4_MOUSE
NC score	0.242432 (rank : 344)	θ value	1.38821 (rank : 517)
Query Neighborhood Hits	671	Target Neighborhood Hits	191	Shared Neighborhood Hits	121
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

NRX3A_HUMAN
NC score	0.240126 (rank : 345)	θ value	1.81305 (rank : 539)
Query Neighborhood Hits	671	Target Neighborhood Hits	164	Shared Neighborhood Hits	130
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

BMPER_HUMAN
NC score	0.238665 (rank : 346)	θ value	0.163984 (rank : 425)
Query Neighborhood Hits	671	Target Neighborhood Hits	175	Shared Neighborhood Hits	139
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

MT3_HUMAN
NC score	0.238112 (rank : 347)	θ value	0.125558 (rank : 420)
Query Neighborhood Hits	671	Target Neighborhood Hits	82	Shared Neighborhood Hits	73
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

FA12_HUMAN
NC score	0.236368 (rank : 348)	θ value	7.59969e-07 (rank : 254)
Query Neighborhood Hits	671	Target Neighborhood Hits	425	Shared Neighborhood Hits	229
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

KRA24_HUMAN
NC score	0.235018 (rank : 349)	θ value	0.163984 (rank : 430)
Query Neighborhood Hits	671	Target Neighborhood Hits	192	Shared Neighborhood Hits	150
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

ASTN_HUMAN
NC score	0.231835 (rank : 350)	θ value	2.44474e-05 (rank : 287)
Query Neighborhood Hits	671	Target Neighborhood Hits	105	Shared Neighborhood Hits	84
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

NRX2A_HUMAN
NC score	0.229952 (rank : 351)	θ value	0.365318 (rank : 469)
Query Neighborhood Hits	671	Target Neighborhood Hits	614	Shared Neighborhood Hits	146
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

ASTN_MOUSE
NC score	0.229183 (rank : 352)	θ value	4.92598e-06 (rank : 270)
Query Neighborhood Hits	671	Target Neighborhood Hits	98	Shared Neighborhood Hits	82
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

TIE2_MOUSE
NC score	0.228540 (rank : 353)	θ value	3.17079e-29 (rank : 83)
Query Neighborhood Hits	671	Target Neighborhood Hits	1204	Shared Neighborhood Hits	313
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TIE2_HUMAN
NC score	0.228177 (rank : 354)	θ value	2.68423e-28 (rank : 86)
Query Neighborhood Hits	671	Target Neighborhood Hits	1192	Shared Neighborhood Hits	299
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

CORIN_HUMAN
NC score	0.226780 (rank : 355)	θ value	0.47712 (rank : 474)
Query Neighborhood Hits	671	Target Neighborhood Hits	453	Shared Neighborhood Hits	233
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

MT4_MOUSE
NC score	0.226489 (rank : 356)	θ value	1.06291 (rank : 506)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	95
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

PGCB_HUMAN
NC score	0.225923 (rank : 357)	θ value	3.0926 (rank : 570)
Query Neighborhood Hits	671	Target Neighborhood Hits	478	Shared Neighborhood Hits	180
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

RECK_HUMAN
NC score	0.224442 (rank : 358)	θ value	8.99809 (rank : 665)
Query Neighborhood Hits	671	Target Neighborhood Hits	189	Shared Neighborhood Hits	136
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

CNTP2_MOUSE
NC score	0.223871 (rank : 359)	θ value	0.813845 (rank : 491)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	139
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

MUC2_HUMAN
NC score	0.223144 (rank : 360)	θ value	0.00134147 (rank : 326)
Query Neighborhood Hits	671	Target Neighborhood Hits	906	Shared Neighborhood Hits	198
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CNTP2_HUMAN
NC score	0.221289 (rank : 361)	θ value	0.813845 (rank : 490)
Query Neighborhood Hits	671	Target Neighborhood Hits	199	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

ADA11_HUMAN
NC score	0.219273 (rank : 362)	θ value	7.1131e-05 (rank : 291)
Query Neighborhood Hits	671	Target Neighborhood Hits	259	Shared Neighborhood Hits	214
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

LCE2C_HUMAN
NC score	0.219220 (rank : 363)	θ value	0.00175202 (rank : 330)
Query Neighborhood Hits	671	Target Neighborhood Hits	53	Shared Neighborhood Hits	37
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

TNR25_HUMAN
NC score	0.218970 (rank : 364)	θ value	0.125558 (rank : 423)
Query Neighborhood Hits	671	Target Neighborhood Hits	172	Shared Neighborhood Hits	104
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

ADA11_MOUSE
NC score	0.218917 (rank : 365)	θ value	4.92598e-06 (rank : 269)
Query Neighborhood Hits	671	Target Neighborhood Hits	263	Shared Neighborhood Hits	214
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

LRP3_HUMAN
NC score	0.214865 (rank : 366)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	671	Target Neighborhood Hits	280	Shared Neighborhood Hits	134
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

C1RA_MOUSE
NC score	0.213714 (rank : 367)	θ value	1.87187e-05 (rank : 283)
Query Neighborhood Hits	671	Target Neighborhood Hits	379	Shared Neighborhood Hits	171
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

TNR16_HUMAN
NC score	0.212832 (rank : 368)	θ value	0.279714 (rank : 457)
Query Neighborhood Hits	671	Target Neighborhood Hits	183	Shared Neighborhood Hits	127
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

CO6_HUMAN
NC score	0.212803 (rank : 369)	θ value	0.365318 (rank : 462)
Query Neighborhood Hits	671	Target Neighborhood Hits	331	Shared Neighborhood Hits	191
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

ADAM8_MOUSE
NC score	0.212344 (rank : 370)	θ value	1.43324e-05 (rank : 277)
Query Neighborhood Hits	671	Target Neighborhood Hits	326	Shared Neighborhood Hits	220
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

C1RB_MOUSE
NC score	0.210622 (rank : 371)	θ value	1.87187e-05 (rank : 284)
Query Neighborhood Hits	671	Target Neighborhood Hits	380	Shared Neighborhood Hits	171
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

ADA15_MOUSE
NC score	0.210466 (rank : 372)	θ value	1.69304e-06 (rank : 261)
Query Neighborhood Hits	671	Target Neighborhood Hits	324	Shared Neighborhood Hits	224
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADAM8_HUMAN
NC score	0.210099 (rank : 373)	θ value	0.00035302 (rank : 311)
Query Neighborhood Hits	671	Target Neighborhood Hits	327	Shared Neighborhood Hits	232
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

CNTP4_MOUSE
NC score	0.207358 (rank : 374)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	671	Target Neighborhood Hits	193	Shared Neighborhood Hits	137
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CORIN_MOUSE
NC score	0.206425 (rank : 375)	θ value	0.0563607 (rank : 395)
Query Neighborhood Hits	671	Target Neighborhood Hits	451	Shared Neighborhood Hits	222
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

KR413_HUMAN
NC score	0.206391 (rank : 376)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	671	Target Neighborhood Hits	112	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

LCE2D_HUMAN
NC score	0.205919 (rank : 377)	θ value	0.00390308 (rank : 345)
Query Neighborhood Hits	671	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE4A_HUMAN
NC score	0.205512 (rank : 378)	θ value	3.0926 (rank : 565)
Query Neighborhood Hits	671	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE2A_HUMAN
NC score	0.205064 (rank : 379)	θ value	0.21417 (rank : 440)
Query Neighborhood Hits	671	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

TNR16_MOUSE
NC score	0.204524 (rank : 380)	θ value	1.81305 (rank : 542)
Query Neighborhood Hits	671	Target Neighborhood Hits	178	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

CNTP4_HUMAN
NC score	0.204503 (rank : 381)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	671	Target Neighborhood Hits	187	Shared Neighborhood Hits	119
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

MEP1A_MOUSE
NC score	0.201664 (rank : 382)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	671	Target Neighborhood Hits	166	Shared Neighborhood Hits	130
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

WFDC3_HUMAN
NC score	0.200183 (rank : 383)	θ value	0.47712 (rank : 478)
Query Neighborhood Hits	671	Target Neighborhood Hits	138	Shared Neighborhood Hits	101
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

MMRN1_HUMAN
NC score	0.198879 (rank : 384)	θ value	5.27518 (rank : 607)
Query Neighborhood Hits	671	Target Neighborhood Hits	636	Shared Neighborhood Hits	154
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

ADA23_HUMAN
NC score	0.197733 (rank : 385)	θ value	0.365318 (rank : 459)
Query Neighborhood Hits	671	Target Neighborhood Hits	235	Shared Neighborhood Hits	192
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

C1R_HUMAN
NC score	0.197401 (rank : 386)	θ value	1.87187e-05 (rank : 285)
Query Neighborhood Hits	671	Target Neighborhood Hits	364	Shared Neighborhood Hits	161
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

MEP1A_HUMAN
NC score	0.197378 (rank : 387)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	671	Target Neighborhood Hits	162	Shared Neighborhood Hits	128
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

ADA15_HUMAN
NC score	0.196161 (rank : 388)	θ value	0.000602161 (rank : 315)
Query Neighborhood Hits	671	Target Neighborhood Hits	288	Shared Neighborhood Hits	214
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

CO7_HUMAN
NC score	0.194854 (rank : 389)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	671	Target Neighborhood Hits	278	Shared Neighborhood Hits	158
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

MFGM_HUMAN
NC score	0.194248 (rank : 390)	θ value	0.279714 (rank : 451)
Query Neighborhood Hits	671	Target Neighborhood Hits	150	Shared Neighborhood Hits	120
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

ST14_HUMAN
NC score	0.193934 (rank : 391)	θ value	0.163984 (rank : 433)
Query Neighborhood Hits	671	Target Neighborhood Hits	409	Shared Neighborhood Hits	202
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

MCSP_MOUSE
NC score	0.193783 (rank : 392)	θ value	0.365318 (rank : 468)
Query Neighborhood Hits	671	Target Neighborhood Hits	108	Shared Neighborhood Hits	70
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

CNTP3_HUMAN
NC score	0.193579 (rank : 393)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	671	Target Neighborhood Hits	195	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

ADA23_MOUSE
NC score	0.193370 (rank : 394)	θ value	1.81305 (rank : 530)
Query Neighborhood Hits	671	Target Neighborhood Hits	245	Shared Neighborhood Hits	207
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

LCE2B_HUMAN
NC score	0.192176 (rank : 395)	θ value	0.00134147 (rank : 325)
Query Neighborhood Hits	671	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

ST14_MOUSE
NC score	0.191010 (rank : 396)	θ value	θ > 10 (rank : 893)
Query Neighborhood Hits	671	Target Neighborhood Hits	419	Shared Neighborhood Hits	206
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

PGCA_HUMAN
NC score	0.189697 (rank : 397)	θ value	0.163984 (rank : 431)
Query Neighborhood Hits	671	Target Neighborhood Hits	821	Shared Neighborhood Hits	189
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

ADA19_MOUSE
NC score	0.189602 (rank : 398)	θ value	0.0961366 (rank : 410)
Query Neighborhood Hits	671	Target Neighborhood Hits	315	Shared Neighborhood Hits	209
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

MASP2_HUMAN
NC score	0.188868 (rank : 399)	θ value	1.38499e-08 (rank : 219)
Query Neighborhood Hits	671	Target Neighborhood Hits	364	Shared Neighborhood Hits	156
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MUC13_HUMAN
NC score	0.185652 (rank : 400)	θ value	1.38821 (rank : 522)
Query Neighborhood Hits	671	Target Neighborhood Hits	164	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

TNR4_MOUSE
NC score	0.185649 (rank : 401)	θ value	0.0193708 (rank : 378)
Query Neighborhood Hits	671	Target Neighborhood Hits	137	Shared Neighborhood Hits	97
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

NRG2_MOUSE
NC score	0.185036 (rank : 402)	θ value	0.0563607 (rank : 398)
Query Neighborhood Hits	671	Target Neighborhood Hits	392	Shared Neighborhood Hits	128
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

MASP2_MOUSE
NC score	0.184714 (rank : 403)	θ value	1.53129e-07 (rank : 237)
Query Neighborhood Hits	671	Target Neighborhood Hits	382	Shared Neighborhood Hits	162
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

ADA10_HUMAN
NC score	0.183941 (rank : 404)	θ value	0.21417 (rank : 436)
Query Neighborhood Hits	671	Target Neighborhood Hits	189	Shared Neighborhood Hits	151
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

RECK_MOUSE
NC score	0.183747 (rank : 405)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	671	Target Neighborhood Hits	158	Shared Neighborhood Hits	112
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

ADA19_HUMAN
NC score	0.183436 (rank : 406)	θ value	0.0431538 (rank : 390)
Query Neighborhood Hits	671	Target Neighborhood Hits	381	Shared Neighborhood Hits	190
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

SMDF_HUMAN
NC score	0.183282 (rank : 407)	θ value	1.38821 (rank : 525)
Query Neighborhood Hits	671	Target Neighborhood Hits	117	Shared Neighborhood Hits	83
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

MT4_HUMAN
NC score	0.182925 (rank : 408)	θ value	3.0926 (rank : 567)
Query Neighborhood Hits	671	Target Neighborhood Hits	83	Shared Neighborhood Hits	76
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ADA33_HUMAN
NC score	0.182571 (rank : 409)	θ value	1.69304e-06 (rank : 262)
Query Neighborhood Hits	671	Target Neighborhood Hits	264	Shared Neighborhood Hits	184
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM9_MOUSE
NC score	0.182003 (rank : 410)	θ value	0.000461057 (rank : 314)
Query Neighborhood Hits	671	Target Neighborhood Hits	325	Shared Neighborhood Hits	217
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

CD320_HUMAN
NC score	0.181651 (rank : 411)	θ value	4.03905 (rank : 578)
Query Neighborhood Hits	671	Target Neighborhood Hits	103	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CS1A_MOUSE
NC score	0.180987 (rank : 412)	θ value	0.00175202 (rank : 328)
Query Neighborhood Hits	671	Target Neighborhood Hits	360	Shared Neighborhood Hits	151
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

NRG4_HUMAN
NC score	0.180510 (rank : 413)	θ value	2.36792 (rank : 553)
Query Neighborhood Hits	671	Target Neighborhood Hits	85	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

CNTP1_HUMAN
NC score	0.180442 (rank : 414)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	671	Target Neighborhood Hits	196	Shared Neighborhood Hits	116
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

ADA18_MOUSE
NC score	0.179957 (rank : 415)	θ value	1.38821 (rank : 512)
Query Neighborhood Hits	671	Target Neighborhood Hits	227	Shared Neighborhood Hits	189
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

VEGFC_HUMAN
NC score	0.179834 (rank : 416)	θ value	0.365318 (rank : 472)
Query Neighborhood Hits	671	Target Neighborhood Hits	128	Shared Neighborhood Hits	107
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CS1B_MOUSE
NC score	0.179747 (rank : 417)	θ value	0.00134147 (rank : 323)
Query Neighborhood Hits	671	Target Neighborhood Hits	361	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CO8B_MOUSE
NC score	0.178871 (rank : 418)	θ value	0.0330416 (rank : 385)
Query Neighborhood Hits	671	Target Neighborhood Hits	224	Shared Neighborhood Hits	135
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

MASP1_HUMAN
NC score	0.178375 (rank : 419)	θ value	1.43324e-05 (rank : 280)
Query Neighborhood Hits	671	Target Neighborhood Hits	369	Shared Neighborhood Hits	157
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

LRP12_HUMAN
NC score	0.177242 (rank : 420)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	671	Target Neighborhood Hits	205	Shared Neighborhood Hits	107
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

FSTL3_HUMAN
NC score	0.177048 (rank : 421)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	671	Target Neighborhood Hits	162	Shared Neighborhood Hits	108
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ADA33_MOUSE
NC score	0.176582 (rank : 422)	θ value	0.000121331 (rank : 302)
Query Neighborhood Hits	671	Target Neighborhood Hits	231	Shared Neighborhood Hits	183
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA10_MOUSE
NC score	0.176461 (rank : 423)	θ value	0.125558 (rank : 415)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	149
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA17_HUMAN
NC score	0.176456 (rank : 424)	θ value	1.81305 (rank : 529)
Query Neighborhood Hits	671	Target Neighborhood Hits	223	Shared Neighborhood Hits	166
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

LRP12_MOUSE
NC score	0.175860 (rank : 425)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	671	Target Neighborhood Hits	180	Shared Neighborhood Hits	100
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

C1S_HUMAN
NC score	0.175606 (rank : 426)	θ value	0.00509761 (rank : 347)
Query Neighborhood Hits	671	Target Neighborhood Hits	359	Shared Neighborhood Hits	157
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

NRG1_HUMAN
NC score	0.175015 (rank : 427)	θ value	6.88961 (rank : 634)
Query Neighborhood Hits	671	Target Neighborhood Hits	285	Shared Neighborhood Hits	102
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

MASP1_MOUSE
NC score	0.174924 (rank : 428)	θ value	1.43324e-05 (rank : 281)
Query Neighborhood Hits	671	Target Neighborhood Hits	364	Shared Neighborhood Hits	158
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

LRP10_MOUSE
NC score	0.174401 (rank : 429)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	671	Target Neighborhood Hits	169	Shared Neighborhood Hits	93
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_HUMAN
NC score	0.173708 (rank : 430)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	671	Target Neighborhood Hits	197	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

MKS3_MOUSE
NC score	0.173586 (rank : 431)	θ value	0.62314 (rank : 487)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	77
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

CNTP1_MOUSE
NC score	0.173477 (rank : 432)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	671	Target Neighborhood Hits	183	Shared Neighborhood Hits	107
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

ZNFX1_HUMAN
NC score	0.172481 (rank : 433)	θ value	7.1131e-05 (rank : 297)
Query Neighborhood Hits	671	Target Neighborhood Hits	308	Shared Neighborhood Hits	155
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ADAM9_HUMAN
NC score	0.170763 (rank : 434)	θ value	0.00390308 (rank : 343)
Query Neighborhood Hits	671	Target Neighborhood Hits	243	Shared Neighborhood Hits	198
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

FSTL3_MOUSE
NC score	0.170462 (rank : 435)	θ value	5.27518 (rank : 600)
Query Neighborhood Hits	671	Target Neighborhood Hits	152	Shared Neighborhood Hits	103
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ADA22_MOUSE
NC score	0.169846 (rank : 436)	θ value	0.0148317 (rank : 369)
Query Neighborhood Hits	671	Target Neighborhood Hits	225	Shared Neighborhood Hits	178
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

LORI_MOUSE
NC score	0.168252 (rank : 437)	θ value	0.0193708 (rank : 377)
Query Neighborhood Hits	671	Target Neighborhood Hits	47	Shared Neighborhood Hits	23
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

TNR14_HUMAN
NC score	0.167973 (rank : 438)	θ value	0.0113563 (rank : 368)
Query Neighborhood Hits	671	Target Neighborhood Hits	149	Shared Neighborhood Hits	112
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ADAM7_HUMAN
NC score	0.167840 (rank : 439)	θ value	0.0736092 (rank : 399)
Query Neighborhood Hits	671	Target Neighborhood Hits	221	Shared Neighborhood Hits	183
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

NRG4_MOUSE
NC score	0.166645 (rank : 440)	θ value	6.88961 (rank : 635)
Query Neighborhood Hits	671	Target Neighborhood Hits	79	Shared Neighborhood Hits	69
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

ZNFX1_MOUSE
NC score	0.166544 (rank : 441)	θ value	0.00869519 (rank : 361)
Query Neighborhood Hits	671	Target Neighborhood Hits	407	Shared Neighborhood Hits	165
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

TNR4_HUMAN
NC score	0.165676 (rank : 442)	θ value	0.365318 (rank : 470)
Query Neighborhood Hits	671	Target Neighborhood Hits	152	Shared Neighborhood Hits	96
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

KR124_HUMAN
NC score	0.164785 (rank : 443)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	671	Target Neighborhood Hits	124	Shared Neighborhood Hits	97
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

ADM1A_MOUSE
NC score	0.162985 (rank : 444)	θ value	1.81305 (rank : 531)
Query Neighborhood Hits	671	Target Neighborhood Hits	230	Shared Neighborhood Hits	186
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA28_HUMAN
NC score	0.162659 (rank : 445)	θ value	7.1131e-05 (rank : 292)
Query Neighborhood Hits	671	Target Neighborhood Hits	244	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

RSPO3_HUMAN
NC score	0.161957 (rank : 446)	θ value	0.21417 (rank : 443)
Query Neighborhood Hits	671	Target Neighborhood Hits	128	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

LCE5A_HUMAN
NC score	0.160698 (rank : 447)	θ value	0.0113563 (rank : 365)
Query Neighborhood Hits	671	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

ADAM2_MOUSE
NC score	0.160218 (rank : 448)	θ value	0.813845 (rank : 489)
Query Neighborhood Hits	671	Target Neighborhood Hits	209	Shared Neighborhood Hits	166
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

APR3_MOUSE
NC score	0.160062 (rank : 449)	θ value	0.62314 (rank : 480)
Query Neighborhood Hits	671	Target Neighborhood Hits	61	Shared Neighborhood Hits	58
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

MT1A_HUMAN
NC score	0.159880 (rank : 450)	θ value	0.21417 (rank : 441)
Query Neighborhood Hits	671	Target Neighborhood Hits	74	Shared Neighborhood Hits	68
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

ADA22_HUMAN
NC score	0.158926 (rank : 451)	θ value	0.00390308 (rank : 342)
Query Neighborhood Hits	671	Target Neighborhood Hits	211	Shared Neighborhood Hits	165
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

MKS3_HUMAN
NC score	0.158888 (rank : 452)	θ value	3.0926 (rank : 566)
Query Neighborhood Hits	671	Target Neighborhood Hits	79	Shared Neighborhood Hits	76
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

ADA12_HUMAN
NC score	0.158853 (rank : 453)	θ value	0.163984 (rank : 424)
Query Neighborhood Hits	671	Target Neighborhood Hits	224	Shared Neighborhood Hits	159
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

PGH2_MOUSE
NC score	0.158374 (rank : 454)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	671	Target Neighborhood Hits	113	Shared Neighborhood Hits	93
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

ADA28_MOUSE
NC score	0.158269 (rank : 455)	θ value	0.00134147 (rank : 322)
Query Neighborhood Hits	671	Target Neighborhood Hits	241	Shared Neighborhood Hits	191
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

ADA18_HUMAN
NC score	0.157824 (rank : 456)	θ value	0.00390308 (rank : 341)
Query Neighborhood Hits	671	Target Neighborhood Hits	184	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

NRG2_HUMAN
NC score	0.156372 (rank : 457)	θ value	0.0563607 (rank : 397)
Query Neighborhood Hits	671	Target Neighborhood Hits	419	Shared Neighborhood Hits	114
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

MT1X_HUMAN
NC score	0.156313 (rank : 458)	θ value	2.36792 (rank : 552)
Query Neighborhood Hits	671	Target Neighborhood Hits	76	Shared Neighborhood Hits	73
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

ADA30_HUMAN
NC score	0.155782 (rank : 459)	θ value	0.813845 (rank : 488)
Query Neighborhood Hits	671	Target Neighborhood Hits	391	Shared Neighborhood Hits	149
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA32_HUMAN
NC score	0.154007 (rank : 460)	θ value	1.06291 (rank : 503)
Query Neighborhood Hits	671	Target Neighborhood Hits	216	Shared Neighborhood Hits	175
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

RSPO4_HUMAN
NC score	0.153626 (rank : 461)	θ value	0.00509761 (rank : 348)
Query Neighborhood Hits	671	Target Neighborhood Hits	110	Shared Neighborhood Hits	88
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

TNR9_HUMAN
NC score	0.152109 (rank : 462)	θ value	3.0926 (rank : 574)
Query Neighborhood Hits	671	Target Neighborhood Hits	166	Shared Neighborhood Hits	130
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

VEGFC_MOUSE
NC score	0.152102 (rank : 463)	θ value	θ > 10 (rank : 928)
Query Neighborhood Hits	671	Target Neighborhood Hits	119	Shared Neighborhood Hits	98
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CT127_HUMAN
NC score	0.151985 (rank : 464)	θ value	0.279714 (rank : 447)
Query Neighborhood Hits	671	Target Neighborhood Hits	67	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

MT1B_HUMAN
NC score	0.151831 (rank : 465)	θ value	0.279714 (rank : 452)
Query Neighborhood Hits	671	Target Neighborhood Hits	87	Shared Neighborhood Hits	80
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

FST_MOUSE
NC score	0.151376 (rank : 466)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	671	Target Neighborhood Hits	146	Shared Neighborhood Hits	96
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

KR122_HUMAN
NC score	0.149995 (rank : 467)	θ value	8.99809 (rank : 659)
Query Neighborhood Hits	671	Target Neighborhood Hits	97	Shared Neighborhood Hits	74
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

MT2_MOUSE
NC score	0.148913 (rank : 468)	θ value	0.279714 (rank : 454)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	73
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

ADAM2_HUMAN
NC score	0.148586 (rank : 469)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	671	Target Neighborhood Hits	175	Shared Neighborhood Hits	145
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

TPA_MOUSE
NC score	0.148542 (rank : 470)	θ value	0.813845 (rank : 500)
Query Neighborhood Hits	671	Target Neighborhood Hits	335	Shared Neighborhood Hits	179
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

EREG_HUMAN
NC score	0.148017 (rank : 471)	θ value	0.365318 (rank : 465)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	63
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

TNR7_HUMAN
NC score	0.148005 (rank : 472)	θ value	2.36792 (rank : 557)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	97
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TPA_HUMAN
NC score	0.147165 (rank : 473)	θ value	2.36792 (rank : 558)
Query Neighborhood Hits	671	Target Neighborhood Hits	324	Shared Neighborhood Hits	170
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

ADA17_MOUSE
NC score	0.146930 (rank : 474)	θ value	1.38821 (rank : 511)
Query Neighborhood Hits	671	Target Neighborhood Hits	201	Shared Neighborhood Hits	154
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA25_MOUSE
NC score	0.146885 (rank : 475)	θ value	0.0431538 (rank : 391)
Query Neighborhood Hits	671	Target Neighborhood Hits	213	Shared Neighborhood Hits	167
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ADM1B_MOUSE
NC score	0.146481 (rank : 476)	θ value	1.38821 (rank : 513)
Query Neighborhood Hits	671	Target Neighborhood Hits	236	Shared Neighborhood Hits	161
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA21_MOUSE
NC score	0.145949 (rank : 477)	θ value	0.62314 (rank : 479)
Query Neighborhood Hits	671	Target Neighborhood Hits	172	Shared Neighborhood Hits	138
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

RSPO3_MOUSE
NC score	0.145695 (rank : 478)	θ value	0.279714 (rank : 455)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

APR3_HUMAN
NC score	0.145688 (rank : 479)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	671	Target Neighborhood Hits	50	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

PGH2_HUMAN
NC score	0.145650 (rank : 480)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	671	Target Neighborhood Hits	103	Shared Neighborhood Hits	82
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

ADA32_MOUSE
NC score	0.145340 (rank : 481)	θ value	0.125558 (rank : 416)
Query Neighborhood Hits	671	Target Neighborhood Hits	219	Shared Neighborhood Hits	178
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CO9_MOUSE
NC score	0.143859 (rank : 482)	θ value	6.88961 (rank : 621)
Query Neighborhood Hits	671	Target Neighborhood Hits	153	Shared Neighborhood Hits	105
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

ADA24_MOUSE
NC score	0.143269 (rank : 483)	θ value	8.99809 (rank : 647)
Query Neighborhood Hits	671	Target Neighborhood Hits	230	Shared Neighborhood Hits	183
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ADAM7_MOUSE
NC score	0.142606 (rank : 484)	θ value	1.06291 (rank : 504)
Query Neighborhood Hits	671	Target Neighborhood Hits	200	Shared Neighborhood Hits	156
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

SHBG_HUMAN
NC score	0.142568 (rank : 485)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	671	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

LCE3B_HUMAN
NC score	0.142338 (rank : 486)	θ value	8.99809 (rank : 660)
Query Neighborhood Hits	671	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

TNR9_MOUSE
NC score	0.142166 (rank : 487)	θ value	θ > 10 (rank : 922)
Query Neighborhood Hits	671	Target Neighborhood Hits	137	Shared Neighborhood Hits	109
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

RSPO4_MOUSE
NC score	0.141508 (rank : 488)	θ value	0.0252991 (rank : 381)
Query Neighborhood Hits	671	Target Neighborhood Hits	110	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

MT1_MOUSE
NC score	0.140735 (rank : 489)	θ value	0.813845 (rank : 498)
Query Neighborhood Hits	671	Target Neighborhood Hits	72	Shared Neighborhood Hits	65
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

PAPPA_MOUSE
NC score	0.140439 (rank : 490)	θ value	1.69304e-06 (rank : 264)
Query Neighborhood Hits	671	Target Neighborhood Hits	153	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_HUMAN
NC score	0.139881 (rank : 491)	θ value	2.61198e-07 (rank : 246)
Query Neighborhood Hits	671	Target Neighborhood Hits	161	Shared Neighborhood Hits	86
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

TMPS6_HUMAN
NC score	0.139814 (rank : 492)	θ value	0.163984 (rank : 434)
Query Neighborhood Hits	671	Target Neighborhood Hits	338	Shared Neighborhood Hits	147
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ADA21_HUMAN
NC score	0.139432 (rank : 493)	θ value	0.279714 (rank : 445)
Query Neighborhood Hits	671	Target Neighborhood Hits	181	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA12_MOUSE
NC score	0.139129 (rank : 494)	θ value	0.0431538 (rank : 389)
Query Neighborhood Hits	671	Target Neighborhood Hits	474	Shared Neighborhood Hits	146
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CO8B_HUMAN
NC score	0.138405 (rank : 495)	θ value	1.38821 (rank : 516)
Query Neighborhood Hits	671	Target Neighborhood Hits	199	Shared Neighborhood Hits	108
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

VASN_HUMAN
NC score	0.137353 (rank : 496)	θ value	0.0330416 (rank : 388)
Query Neighborhood Hits	671	Target Neighborhood Hits	449	Shared Neighborhood Hits	138
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

SHBG_MOUSE
NC score	0.136738 (rank : 497)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	671	Target Neighborhood Hits	50	Shared Neighborhood Hits	35
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

PGH1_MOUSE
NC score	0.136712 (rank : 498)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	671	Target Neighborhood Hits	100	Shared Neighborhood Hits	75
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

CO8A_HUMAN
NC score	0.135909 (rank : 499)	θ value	4.03905 (rank : 579)
Query Neighborhood Hits	671	Target Neighborhood Hits	200	Shared Neighborhood Hits	117
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO9_HUMAN
NC score	0.135718 (rank : 500)	θ value	5.27518 (rank : 597)
Query Neighborhood Hits	671	Target Neighborhood Hits	147	Shared Neighborhood Hits	97
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

FST_HUMAN
NC score	0.135206 (rank : 501)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	671	Target Neighborhood Hits	129	Shared Neighborhood Hits	79
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

MEP1B_MOUSE
NC score	0.134194 (rank : 502)	θ value	8.99809 (rank : 661)
Query Neighborhood Hits	671	Target Neighborhood Hits	127	Shared Neighborhood Hits	88
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

TNR23_MOUSE
NC score	0.134152 (rank : 503)	θ value	θ > 10 (rank : 918)
Query Neighborhood Hits	671	Target Neighborhood Hits	114	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

MT1H_HUMAN
NC score	0.133824 (rank : 504)	θ value	0.21417 (rank : 442)
Query Neighborhood Hits	671	Target Neighborhood Hits	78	Shared Neighborhood Hits	71
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

SPR2D_MOUSE
NC score	0.132538 (rank : 505)	θ value	0.0736092 (rank : 406)
Query Neighborhood Hits	671	Target Neighborhood Hits	61	Shared Neighborhood Hits	24
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

TNR11_HUMAN
NC score	0.131872 (rank : 506)	θ value	0.813845 (rank : 499)
Query Neighborhood Hits	671	Target Neighborhood Hits	135	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TMPS6_MOUSE
NC score	0.131374 (rank : 507)	θ value	0.0148317 (rank : 372)
Query Neighborhood Hits	671	Target Neighborhood Hits	341	Shared Neighborhood Hits	149
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TNR8_MOUSE
NC score	0.129112 (rank : 508)	θ value	θ > 10 (rank : 921)
Query Neighborhood Hits	671	Target Neighborhood Hits	208	Shared Neighborhood Hits	102
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

CYR61_MOUSE
NC score	0.128962 (rank : 509)	θ value	0.00228821 (rank : 334)
Query Neighborhood Hits	671	Target Neighborhood Hits	156	Shared Neighborhood Hits	102
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

CYR61_HUMAN
NC score	0.127813 (rank : 510)	θ value	0.00228821 (rank : 333)
Query Neighborhood Hits	671	Target Neighborhood Hits	159	Shared Neighborhood Hits	106
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

VASN_MOUSE
NC score	0.127615 (rank : 511)	θ value	0.0736092 (rank : 409)
Query Neighborhood Hits	671	Target Neighborhood Hits	426	Shared Neighborhood Hits	128
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

TNR5_MOUSE
NC score	0.126849 (rank : 512)	θ value	0.21417 (rank : 444)
Query Neighborhood Hits	671	Target Neighborhood Hits	131	Shared Neighborhood Hits	98
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

ADA29_HUMAN
NC score	0.126769 (rank : 513)	θ value	4.03905 (rank : 577)
Query Neighborhood Hits	671	Target Neighborhood Hits	247	Shared Neighborhood Hits	126
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

TNR8_HUMAN
NC score	0.125711 (rank : 514)	θ value	4.03905 (rank : 593)
Query Neighborhood Hits	671	Target Neighborhood Hits	198	Shared Neighborhood Hits	98
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

CO8A_MOUSE
NC score	0.124505 (rank : 515)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	671	Target Neighborhood Hits	182	Shared Neighborhood Hits	98
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

FINC_MOUSE
NC score	0.124260 (rank : 516)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	671	Target Neighborhood Hits	309	Shared Neighborhood Hits	77
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FINC_HUMAN
NC score	0.122981 (rank : 517)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	671	Target Neighborhood Hits	302	Shared Neighborhood Hits	74
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

RSPO2_MOUSE
NC score	0.120777 (rank : 518)	θ value	0.0148317 (rank : 371)
Query Neighborhood Hits	671	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

WISP2_HUMAN
NC score	0.120082 (rank : 519)	θ value	0.0148317 (rank : 373)
Query Neighborhood Hits	671	Target Neighborhood Hits	126	Shared Neighborhood Hits	81
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

TNR22_MOUSE
NC score	0.119760 (rank : 520)	θ value	θ > 10 (rank : 917)
Query Neighborhood Hits	671	Target Neighborhood Hits	97	Shared Neighborhood Hits	71
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

RSPO2_HUMAN
NC score	0.119218 (rank : 521)	θ value	0.00869519 (rank : 360)
Query Neighborhood Hits	671	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

MFRP_HUMAN
NC score	0.117773 (rank : 522)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	671	Target Neighborhood Hits	165	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

KR111_HUMAN
NC score	0.117010 (rank : 523)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	671	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

SPR2G_MOUSE
NC score	0.116511 (rank : 524)	θ value	0.279714 (rank : 456)
Query Neighborhood Hits	671	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

COCA1_MOUSE
NC score	0.116080 (rank : 525)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	671	Target Neighborhood Hits	467	Shared Neighborhood Hits	57
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

AD26A_MOUSE
NC score	0.115735 (rank : 526)	θ value	1.38821 (rank : 510)
Query Neighborhood Hits	671	Target Neighborhood Hits	165	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

SPR2H_MOUSE
NC score	0.115588 (rank : 527)	θ value	0.0736092 (rank : 407)
Query Neighborhood Hits	671	Target Neighborhood Hits	82	Shared Neighborhood Hits	27
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

MT1L_HUMAN
NC score	0.115149 (rank : 528)	θ value	0.279714 (rank : 453)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	67
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

WISP2_MOUSE
NC score	0.115098 (rank : 529)	θ value	0.00134147 (rank : 327)
Query Neighborhood Hits	671	Target Neighborhood Hits	129	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

COKA1_HUMAN
NC score	0.115063 (rank : 530)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	671	Target Neighborhood Hits	403	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

MT1E_HUMAN
NC score	0.114948 (rank : 531)	θ value	0.125558 (rank : 419)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	71
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

SPR2F_HUMAN
NC score	0.114827 (rank : 532)	θ value	0.163984 (rank : 432)
Query Neighborhood Hits	671	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

BTC_MOUSE
NC score	0.113758 (rank : 533)	θ value	3.0926 (rank : 561)
Query Neighborhood Hits	671	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CTGF_HUMAN
NC score	0.113684 (rank : 534)	θ value	0.163984 (rank : 426)
Query Neighborhood Hits	671	Target Neighborhood Hits	128	Shared Neighborhood Hits	88
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

PGH1_HUMAN
NC score	0.113635 (rank : 535)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	671	Target Neighborhood Hits	91	Shared Neighborhood Hits	68
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

KR123_HUMAN
NC score	0.113591 (rank : 536)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	55
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

COCA1_HUMAN
NC score	0.113490 (rank : 537)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	671	Target Neighborhood Hits	458	Shared Neighborhood Hits	56
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

GP128_MOUSE
NC score	0.111271 (rank : 538)	θ value	0.279714 (rank : 450)
Query Neighborhood Hits	671	Target Neighborhood Hits	141	Shared Neighborhood Hits	55
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

CHRD_HUMAN
NC score	0.111212 (rank : 539)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

DKK3_MOUSE
NC score	0.110646 (rank : 540)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	671	Target Neighborhood Hits	83	Shared Neighborhood Hits	64
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

GP126_HUMAN
NC score	0.110633 (rank : 541)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	671	Target Neighborhood Hits	187	Shared Neighborhood Hits	42
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

TNR11_MOUSE
NC score	0.109800 (rank : 542)	θ value	2.36792 (rank : 556)
Query Neighborhood Hits	671	Target Neighborhood Hits	121	Shared Neighborhood Hits	77
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

BAI1_HUMAN
NC score	0.109556 (rank : 543)	θ value	0.62314 (rank : 482)
Query Neighborhood Hits	671	Target Neighborhood Hits	375	Shared Neighborhood Hits	84
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

TNR3_MOUSE
NC score	0.109508 (rank : 544)	θ value	0.163984 (rank : 435)
Query Neighborhood Hits	671	Target Neighborhood Hits	113	Shared Neighborhood Hits	76
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

CTGF_MOUSE
NC score	0.108815 (rank : 545)	θ value	0.365318 (rank : 463)
Query Neighborhood Hits	671	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

EPGN_MOUSE
NC score	0.108385 (rank : 546)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	671	Target Neighborhood Hits	63	Shared Neighborhood Hits	54
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

COEA1_MOUSE
NC score	0.108255 (rank : 547)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	671	Target Neighborhood Hits	402	Shared Neighborhood Hits	41
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

BAI3_MOUSE
NC score	0.108041 (rank : 548)	θ value	6.88961 (rank : 619)
Query Neighborhood Hits	671	Target Neighborhood Hits	250	Shared Neighborhood Hits	87
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CHRD_MOUSE
NC score	0.107681 (rank : 549)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

TSG6_HUMAN
NC score	0.106479 (rank : 550)	θ value	θ > 10 (rank : 926)
Query Neighborhood Hits	671	Target Neighborhood Hits	91	Shared Neighborhood Hits	35
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
NC score	0.106040 (rank : 551)	θ value	θ > 10 (rank : 927)
Query Neighborhood Hits	671	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

MFRP_MOUSE
NC score	0.105090 (rank : 552)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	671	Target Neighborhood Hits	166	Shared Neighborhood Hits	57
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

COEA1_HUMAN
NC score	0.104876 (rank : 553)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	671	Target Neighborhood Hits	427	Shared Neighborhood Hits	47
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

CSMD1_MOUSE
NC score	0.104690 (rank : 554)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	671	Target Neighborhood Hits	193	Shared Neighborhood Hits	76
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

BAI3_HUMAN
NC score	0.104526 (rank : 555)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	671	Target Neighborhood Hits	246	Shared Neighborhood Hits	85
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BTC_HUMAN
NC score	0.104206 (rank : 556)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	671	Target Neighborhood Hits	70	Shared Neighborhood Hits	57
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

GP128_HUMAN
NC score	0.104166 (rank : 557)	θ value	5.27518 (rank : 601)
Query Neighborhood Hits	671	Target Neighborhood Hits	135	Shared Neighborhood Hits	52
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

MT1G_HUMAN
NC score	0.104007 (rank : 558)	θ value	8.99809 (rank : 662)
Query Neighborhood Hits	671	Target Neighborhood Hits	63	Shared Neighborhood Hits	57
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

BAI1_MOUSE
NC score	0.103418 (rank : 559)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	671	Target Neighborhood Hits	340	Shared Neighborhood Hits	81
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

MT1F_HUMAN
NC score	0.103146 (rank : 560)	θ value	1.81305 (rank : 538)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	68
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

TNR7_MOUSE
NC score	0.102686 (rank : 561)	θ value	5.27518 (rank : 616)
Query Neighborhood Hits	671	Target Neighborhood Hits	112	Shared Neighborhood Hits	83
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

DKK3_HUMAN
NC score	0.102650 (rank : 562)	θ value	8.99809 (rank : 652)
Query Neighborhood Hits	671	Target Neighborhood Hits	74	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

NOV_HUMAN
NC score	0.102601 (rank : 563)	θ value	1.38821 (rank : 523)
Query Neighborhood Hits	671	Target Neighborhood Hits	128	Shared Neighborhood Hits	89
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

CSMD1_HUMAN
NC score	0.102441 (rank : 564)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	671	Target Neighborhood Hits	176	Shared Neighborhood Hits	65
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

ADA20_HUMAN
NC score	0.101915 (rank : 565)	θ value	8.99809 (rank : 646)
Query Neighborhood Hits	671	Target Neighborhood Hits	143	Shared Neighborhood Hits	103
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

BAI2_MOUSE
NC score	0.101615 (rank : 566)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	671	Target Neighborhood Hits	323	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TNR26_MOUSE
NC score	0.100645 (rank : 567)	θ value	5.27518 (rank : 615)
Query Neighborhood Hits	671	Target Neighborhood Hits	106	Shared Neighborhood Hits	79
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

CSMD3_HUMAN
NC score	0.100427 (rank : 568)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	671	Target Neighborhood Hits	199	Shared Neighborhood Hits	70
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

TNR3_HUMAN
NC score	0.100042 (rank : 569)	θ value	0.47712 (rank : 477)
Query Neighborhood Hits	671	Target Neighborhood Hits	145	Shared Neighborhood Hits	73
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

BAI2_HUMAN
NC score	0.099805 (rank : 570)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	671	Target Neighborhood Hits	332	Shared Neighborhood Hits	81
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TNR6B_HUMAN
NC score	0.099726 (rank : 571)	θ value	0.279714 (rank : 458)
Query Neighborhood Hits	671	Target Neighborhood Hits	103	Shared Neighborhood Hits	75
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

MT2_HUMAN
NC score	0.097404 (rank : 572)	θ value	1.38821 (rank : 520)
Query Neighborhood Hits	671	Target Neighborhood Hits	69	Shared Neighborhood Hits	67
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

NETO1_HUMAN
NC score	0.097337 (rank : 573)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	671	Target Neighborhood Hits	110	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

RSPO1_HUMAN
NC score	0.097307 (rank : 574)	θ value	5.27518 (rank : 610)
Query Neighborhood Hits	671	Target Neighborhood Hits	101	Shared Neighborhood Hits	73
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

NETO1_MOUSE
NC score	0.096866 (rank : 575)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	671	Target Neighborhood Hits	109	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

CRDL2_MOUSE
NC score	0.096861 (rank : 576)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

EREG_MOUSE
NC score	0.096614 (rank : 577)	θ value	6.88961 (rank : 624)
Query Neighborhood Hits	671	Target Neighborhood Hits	65	Shared Neighborhood Hits	52
SwissProt Accessions	Q61521, Q7M0A8	Gene names	Ereg
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

KR241_HUMAN
NC score	0.096327 (rank : 578)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	671	Target Neighborhood Hits	71	Shared Neighborhood Hits	50
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

TNR6_MOUSE
NC score	0.096110 (rank : 579)	θ value	0.365318 (rank : 471)
Query Neighborhood Hits	671	Target Neighborhood Hits	99	Shared Neighborhood Hits	67
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

CFAI_MOUSE
NC score	0.096063 (rank : 580)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	671	Target Neighborhood Hits	290	Shared Neighborhood Hits	92
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

TMPS7_HUMAN
NC score	0.095681 (rank : 581)	θ value	θ > 10 (rank : 907)
Query Neighborhood Hits	671	Target Neighborhood Hits	275	Shared Neighborhood Hits	93
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

EPGN_HUMAN
NC score	0.095590 (rank : 582)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	671	Target Neighborhood Hits	59	Shared Neighborhood Hits	49
SwissProt Accessions	Q6UW88	Gene names	EPGN
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

TMPS7_MOUSE
NC score	0.095055 (rank : 583)	θ value	θ > 10 (rank : 908)
Query Neighborhood Hits	671	Target Neighborhood Hits	275	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

MEP1B_HUMAN
NC score	0.094872 (rank : 584)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	671	Target Neighborhood Hits	98	Shared Neighborhood Hits	60
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

UROK_MOUSE
NC score	0.094742 (rank : 585)	θ value	0.0431538 (rank : 394)
Query Neighborhood Hits	671	Target Neighborhood Hits	273	Shared Neighborhood Hits	124
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

CFAI_HUMAN
NC score	0.094655 (rank : 586)	θ value	0.279714 (rank : 446)
Query Neighborhood Hits	671	Target Neighborhood Hits	289	Shared Neighborhood Hits	86
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

SPR2B_MOUSE
NC score	0.094531 (rank : 587)	θ value	4.03905 (rank : 590)
Query Neighborhood Hits	671	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

NETO2_MOUSE
NC score	0.094255 (rank : 588)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	671	Target Neighborhood Hits	113	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_HUMAN
NC score	0.094230 (rank : 589)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	671	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

LCE3C_HUMAN
NC score	0.094013 (rank : 590)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	671	Target Neighborhood Hits	15	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

CSMD2_HUMAN
NC score	0.093760 (rank : 591)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	671	Target Neighborhood Hits	188	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

IDD_HUMAN
NC score	0.093657 (rank : 592)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	671	Target Neighborhood Hits	127	Shared Neighborhood Hits	50
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

NOV_MOUSE
NC score	0.093606 (rank : 593)	θ value	0.125558 (rank : 421)
Query Neighborhood Hits	671	Target Neighborhood Hits	130	Shared Neighborhood Hits	85
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

PROP_MOUSE
NC score	0.092932 (rank : 594)	θ value	0.0330416 (rank : 387)
Query Neighborhood Hits	671	Target Neighborhood Hits	165	Shared Neighborhood Hits	73
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

TNR19_MOUSE
NC score	0.092836 (rank : 595)	θ value	θ > 10 (rank : 912)
Query Neighborhood Hits	671	Target Neighborhood Hits	100	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

GP113_HUMAN
NC score	0.092725 (rank : 596)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

TGFA_HUMAN
NC score	0.092162 (rank : 597)	θ value	6.88961 (rank : 641)
Query Neighborhood Hits	671	Target Neighborhood Hits	61	Shared Neighborhood Hits	53
SwissProt Accessions	P01135, Q15577	Gene names	TGFA
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

CRDL2_HUMAN
NC score	0.091727 (rank : 598)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	671	Target Neighborhood Hits	99	Shared Neighborhood Hits	67
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

UROK_HUMAN
NC score	0.091531 (rank : 599)	θ value	2.36792 (rank : 559)
Query Neighborhood Hits	671	Target Neighborhood Hits	272	Shared Neighborhood Hits	121
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

KR131_HUMAN
NC score	0.091220 (rank : 600)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	671	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

MT1M_HUMAN
NC score	0.091202 (rank : 601)	θ value	4.03905 (rank : 588)
Query Neighborhood Hits	671	Target Neighborhood Hits	72	Shared Neighborhood Hits	66
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

TNR5_HUMAN
NC score	0.090121 (rank : 602)	θ value	θ > 10 (rank : 919)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	75
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

IDD_MOUSE
NC score	0.089295 (rank : 603)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	671	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

GP144_HUMAN
NC score	0.088582 (rank : 604)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	671	Target Neighborhood Hits	108	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

GNPTA_HUMAN
NC score	0.088521 (rank : 605)	θ value	2.36792 (rank : 549)
Query Neighborhood Hits	671	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

KR261_HUMAN
NC score	0.087879 (rank : 606)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	671	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

MT1I_HUMAN
NC score	0.087741 (rank : 607)	θ value	2.36792 (rank : 551)
Query Neighborhood Hits	671	Target Neighborhood Hits	64	Shared Neighborhood Hits	60
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

NRP2_HUMAN
NC score	0.087444 (rank : 608)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	35
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PCOC1_MOUSE
NC score	0.087085 (rank : 609)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	671	Target Neighborhood Hits	100	Shared Neighborhood Hits	27
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

SPR2I_MOUSE
NC score	0.086705 (rank : 610)	θ value	1.06291 (rank : 508)
Query Neighborhood Hits	671	Target Neighborhood Hits	45	Shared Neighborhood Hits	17
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

TMG1_HUMAN
NC score	0.086660 (rank : 611)	θ value	θ > 10 (rank : 896)
Query Neighborhood Hits	671	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	O14668	Gene names	PRRG1, PRGP1, TMG1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 1 precursor (Proline- rich Gla protein 1) (Proline-rich gamma-carboxyglutamic acid protein 1).

PCOC2_HUMAN
NC score	0.086376 (rank : 612)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PAP2_HUMAN
NC score	0.086334 (rank : 613)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	671	Target Neighborhood Hits	106	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

CUZD1_HUMAN
NC score	0.086219 (rank : 614)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	31
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

WISP1_MOUSE
NC score	0.086011 (rank : 615)	θ value	5.27518 (rank : 617)
Query Neighborhood Hits	671	Target Neighborhood Hits	123	Shared Neighborhood Hits	78
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

CO7A1_HUMAN
NC score	0.086007 (rank : 616)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	671	Target Neighborhood Hits	807	Shared Neighborhood Hits	76
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

GNPTA_MOUSE
NC score	0.085870 (rank : 617)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	671	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

ODFP_MOUSE
NC score	0.085636 (rank : 618)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	53
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PCOC2_MOUSE
NC score	0.085435 (rank : 619)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

GP133_HUMAN
NC score	0.085201 (rank : 620)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	671	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

PCOC1_HUMAN
NC score	0.085135 (rank : 621)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	671	Target Neighborhood Hits	146	Shared Neighborhood Hits	27
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

NRP2_MOUSE
NC score	0.084683 (rank : 622)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	671	Target Neighborhood Hits	113	Shared Neighborhood Hits	34
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

WISP1_HUMAN
NC score	0.084662 (rank : 623)	θ value	1.38821 (rank : 528)
Query Neighborhood Hits	671	Target Neighborhood Hits	121	Shared Neighborhood Hits	81
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

HBEGF_HUMAN
NC score	0.084074 (rank : 624)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	671	Target Neighborhood Hits	61	Shared Neighborhood Hits	51
SwissProt Accessions	Q99075	Gene names	HBEGF, DTR, HEGFL
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R).

LPHN2_HUMAN
NC score	0.083608 (rank : 625)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	671	Target Neighborhood Hits	136	Shared Neighborhood Hits	22
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

TNR19_HUMAN
NC score	0.083312 (rank : 626)	θ value	6.88961 (rank : 644)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

SEZ6L_HUMAN
NC score	0.083266 (rank : 627)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	671	Target Neighborhood Hits	289	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

LPHN3_HUMAN
NC score	0.083149 (rank : 628)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	671	Target Neighborhood Hits	139	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

GP112_HUMAN
NC score	0.082902 (rank : 629)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	671	Target Neighborhood Hits	441	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

TNR1A_MOUSE
NC score	0.082373 (rank : 630)	θ value	θ > 10 (rank : 914)
Query Neighborhood Hits	671	Target Neighborhood Hits	131	Shared Neighborhood Hits	74
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

LPHN1_HUMAN
NC score	0.082284 (rank : 631)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	671	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

RSPO1_MOUSE
NC score	0.082051 (rank : 632)	θ value	8.99809 (rank : 666)
Query Neighborhood Hits	671	Target Neighborhood Hits	85	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

PROP_HUMAN
NC score	0.081776 (rank : 633)	θ value	0.00665767 (rank : 355)
Query Neighborhood Hits	671	Target Neighborhood Hits	126	Shared Neighborhood Hits	61
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

ENTK_MOUSE
NC score	0.081561 (rank : 634)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	671	Target Neighborhood Hits	338	Shared Neighborhood Hits	88
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TNR1A_HUMAN
NC score	0.081454 (rank : 635)	θ value	θ > 10 (rank : 913)
Query Neighborhood Hits	671	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR6_HUMAN
NC score	0.081145 (rank : 636)	θ value	θ > 10 (rank : 920)
Query Neighborhood Hits	671	Target Neighborhood Hits	95	Shared Neighborhood Hits	64
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

CUZD1_MOUSE
NC score	0.080896 (rank : 637)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	671	Target Neighborhood Hits	91	Shared Neighborhood Hits	29
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

NRG3_MOUSE
NC score	0.080791 (rank : 638)	θ value	8.99809 (rank : 664)
Query Neighborhood Hits	671	Target Neighborhood Hits	132	Shared Neighborhood Hits	73
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

NRP1_HUMAN
NC score	0.080144 (rank : 639)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	671	Target Neighborhood Hits	119	Shared Neighborhood Hits	35
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
NC score	0.079896 (rank : 640)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	34
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

GP116_HUMAN
NC score	0.079870 (rank : 641)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	671	Target Neighborhood Hits	167	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

TNR1B_HUMAN
NC score	0.079799 (rank : 642)	θ value	θ > 10 (rank : 915)
Query Neighborhood Hits	671	Target Neighborhood Hits	127	Shared Neighborhood Hits	71
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

GP114_HUMAN
NC score	0.079390 (rank : 643)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

PDGFD_MOUSE
NC score	0.078744 (rank : 644)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	671	Target Neighborhood Hits	72	Shared Neighborhood Hits	23
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

KR134_HUMAN
NC score	0.078718 (rank : 645)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	54
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

TMG3_HUMAN
NC score	0.078423 (rank : 646)	θ value	θ > 10 (rank : 899)
Query Neighborhood Hits	671	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD7, Q8N2N6	Gene names	PRRG3, TMG3
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

GPR64_MOUSE
NC score	0.077970 (rank : 647)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	671	Target Neighborhood Hits	156	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

ATS9_HUMAN
NC score	0.077954 (rank : 648)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	671	Target Neighborhood Hits	219	Shared Neighborhood Hits	139
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

NRG3_HUMAN
NC score	0.077706 (rank : 649)	θ value	8.99809 (rank : 663)
Query Neighborhood Hits	671	Target Neighborhood Hits	119	Shared Neighborhood Hits	67
SwissProt Accessions	P56975	Gene names	NRG3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

KR221_HUMAN
NC score	0.077706 (rank : 650)	θ value	0.813845 (rank : 497)
Query Neighborhood Hits	671	Target Neighborhood Hits	6	Shared Neighborhood Hits	6
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

TMG3_MOUSE
NC score	0.077495 (rank : 651)	θ value	θ > 10 (rank : 900)
Query Neighborhood Hits	671	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PAQ9	Gene names	Prrg3, Gm368, Tmg3
Domain Architecture	No domain graphic available
Description	Transmembrane gamma-carboxyglutamic acid protein 3 precursor (Proline- rich Gla protein 3) (Proline-rich gamma-carboxyglutamic acid protein 3).

GPR64_HUMAN
NC score	0.077420 (rank : 652)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	671	Target Neighborhood Hits	207	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

PDGFD_HUMAN
NC score	0.076892 (rank : 653)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	671	Target Neighborhood Hits	74	Shared Neighborhood Hits	23
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

SPR2E_HUMAN
NC score	0.076469 (rank : 654)	θ value	3.0926 (rank : 572)
Query Neighborhood Hits	671	Target Neighborhood Hits	32	Shared Neighborhood Hits	16
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

EPHB4_HUMAN
NC score	0.076072 (rank : 655)	θ value	0.00390308 (rank : 344)
Query Neighborhood Hits	671	Target Neighborhood Hits	1056	Shared Neighborhood Hits	163
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

NEU1_MOUSE
NC score	0.075659 (rank : 656)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	671	Target Neighborhood Hits	64	Shared Neighborhood Hits	54
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

ENTK_HUMAN
NC score	0.075571 (rank : 657)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	671	Target Neighborhood Hits	310	Shared Neighborhood Hits	82
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TGFA_MOUSE
NC score	0.075347 (rank : 658)	θ value	8.99809 (rank : 668)
Query Neighborhood Hits	671	Target Neighborhood Hits	62	Shared Neighborhood Hits	51
SwissProt Accessions	P48030	Gene names	Tgfa
Domain Architecture	No domain graphic available
Description	Transforming growth factor alpha precursor (TGF-alpha) (EGF-like TGF) (ETGF) (TGF type 1).

CRDL1_MOUSE
NC score	0.075266 (rank : 659)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	59
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

VITRN_MOUSE
NC score	0.075196 (rank : 660)	θ value	θ > 10 (rank : 930)
Query Neighborhood Hits	671	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

GPR97_MOUSE
NC score	0.075094 (rank : 661)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

VITRN_HUMAN
NC score	0.074967 (rank : 662)	θ value	θ > 10 (rank : 929)
Query Neighborhood Hits	671	Target Neighborhood Hits	63	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

GPR56_MOUSE
NC score	0.074513 (rank : 663)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

GPR56_HUMAN
NC score	0.074319 (rank : 664)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	671	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

COCH_MOUSE
NC score	0.074053 (rank : 665)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	671	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COCH_HUMAN
NC score	0.073829 (rank : 666)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	671	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

DMBT1_MOUSE
NC score	0.073797 (rank : 667)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	671	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

INSRR_MOUSE
NC score	0.073797 (rank : 668)	θ value	0.00020696 (rank : 308)
Query Neighborhood Hits	671	Target Neighborhood Hits	961	Shared Neighborhood Hits	156
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

CRDL1_HUMAN
NC score	0.073774 (rank : 669)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CSPG4_HUMAN
NC score	0.073699 (rank : 670)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	671	Target Neighborhood Hits	112	Shared Neighborhood Hits	37
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

SPR2E_MOUSE
NC score	0.073382 (rank : 671)	θ value	1.81305 (rank : 540)
Query Neighborhood Hits	671	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

GP110_MOUSE
NC score	0.072951 (rank : 672)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	671	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

SPIT1_HUMAN
NC score	0.072948 (rank : 673)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	671	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	O43278, Q7Z7D2	Gene names	SPINT1, HAI1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

GP110_HUMAN
NC score	0.072703 (rank : 674)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	671	Target Neighborhood Hits	87	Shared Neighborhood Hits	27
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

TNR21_MOUSE
NC score	0.072696 (rank : 675)	θ value	1.06291 (rank : 509)
Query Neighborhood Hits	671	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TR19L_MOUSE
NC score	0.072258 (rank : 676)	θ value	1.38821 (rank : 527)
Query Neighborhood Hits	671	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TR19L_HUMAN
NC score	0.072085 (rank : 677)	θ value	θ > 10 (rank : 925)
Query Neighborhood Hits	671	Target Neighborhood Hits	99	Shared Neighborhood Hits	51
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

INSRR_HUMAN
NC score	0.072080 (rank : 678)	θ value	0.00035302 (rank : 312)
Query Neighborhood Hits	671	Target Neighborhood Hits	950	Shared Neighborhood Hits	143
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

FNDC3_MOUSE
NC score	0.072019 (rank : 679)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	671	Target Neighborhood Hits	207	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

GPR98_HUMAN
NC score	0.071828 (rank : 680)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	671	Target Neighborhood Hits	202	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

TNR18_HUMAN
NC score	0.071097 (rank : 681)	θ value	θ > 10 (rank : 911)
Query Neighborhood Hits	671	Target Neighborhood Hits	55	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

CSPG4_MOUSE
NC score	0.070999 (rank : 682)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	671	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

THYG_HUMAN
NC score	0.070377 (rank : 683)	θ value	0.0736092 (rank : 408)
Query Neighborhood Hits	671	Target Neighborhood Hits	154	Shared Neighborhood Hits	79
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TNR21_HUMAN
NC score	0.070139 (rank : 684)	θ value	0.125558 (rank : 422)
Query Neighborhood Hits	671	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

ATS20_MOUSE
NC score	0.069773 (rank : 685)	θ value	0.125558 (rank : 417)
Query Neighborhood Hits	671	Target Neighborhood Hits	225	Shared Neighborhood Hits	129
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

CFAB_MOUSE
NC score	0.069756 (rank : 686)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	671	Target Neighborhood Hits	262	Shared Neighborhood Hits	64
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

GPR98_MOUSE
NC score	0.069349 (rank : 687)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	671	Target Neighborhood Hits	206	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

GP115_MOUSE
NC score	0.069207 (rank : 688)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	671	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

ADEC1_MOUSE
NC score	0.068959 (rank : 689)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	671	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q9R0X2	Gene names	Adamdec1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

GPR97_HUMAN
NC score	0.068823 (rank : 690)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	671	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

MCSP_HUMAN
NC score	0.068615 (rank : 691)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	671	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

DCBD1_HUMAN
NC score	0.068389 (rank : 692)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	671	Target Neighborhood Hits	110	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

GP115_HUMAN
NC score	0.067312 (rank : 693)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	671	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

KR132_HUMAN
NC score	0.067032 (rank : 694)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	671	Target Neighborhood Hits	69	Shared Neighborhood Hits	48
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

DCBD1_MOUSE
NC score	0.066903 (rank : 695)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	671	Target Neighborhood Hits	89	Shared Neighborhood Hits	21
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

ADEC1_HUMAN
NC score	0.066841 (rank : 696)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	671	Target Neighborhood Hits	80	Shared Neighborhood Hits	47
SwissProt Accessions	O15204	Gene names	ADAMDEC1
Domain Architecture	No domain graphic available
Description	ADAM DEC1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain-like protein decysin 1) (ADAM-like protein decysin 1).

SPIT1_MOUSE
NC score	0.066652 (rank : 697)	θ value	θ > 10 (rank : 889)
Query Neighborhood Hits	671	Target Neighborhood Hits	96	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R097	Gene names	Spint1, Hai1
Domain Architecture
Description	Kunitz-type protease inhibitor 1 precursor (Hepatocyte growth factor activator inhibitor type 1) (HAI-1).

GP111_HUMAN
NC score	0.066607 (rank : 698)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	671	Target Neighborhood Hits	77	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

SPR2F_MOUSE
NC score	0.066513 (rank : 699)	θ value	1.81305 (rank : 541)
Query Neighborhood Hits	671	Target Neighborhood Hits	43	Shared Neighborhood Hits	14
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

TMG2_HUMAN
NC score	0.066438 (rank : 700)	θ value	θ > 10 (rank : 897)
Query Neighborhood Hits	671	Target Neighborhood Hits	25	Shared Neighborhood Hits	14
SwissProt Accessions	O14669	Gene names	PRRG2, PRGP2, TMG2
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2).

MFAP4_MOUSE
NC score	0.066292 (rank : 701)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	671	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_HUMAN
NC score	0.066209 (rank : 702)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	671	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

LRP11_MOUSE
NC score	0.065971 (rank : 703)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CB67, Q8C7Y7	Gene names	Lrp11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

TMG4_HUMAN
NC score	0.065939 (rank : 704)	θ value	θ > 10 (rank : 901)
Query Neighborhood Hits	671	Target Neighborhood Hits	31	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZD6	Gene names	PRRG4, TMG4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

FNDC3_HUMAN
NC score	0.065663 (rank : 705)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	671	Target Neighborhood Hits	196	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

TMG2_MOUSE
NC score	0.065420 (rank : 706)	θ value	θ > 10 (rank : 898)
Query Neighborhood Hits	671	Target Neighborhood Hits	25	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R182, Q9EQI2	Gene names	Prrg2, N4wbp1
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 2 precursor (Proline- rich Gla protein 2) (Proline-rich gamma-carboxyglutamic acid protein 2) (NEDD4 WW domain-binding protein 1).

KR133_HUMAN
NC score	0.065176 (rank : 707)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	671	Target Neighborhood Hits	66	Shared Neighborhood Hits	50
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

ATS20_HUMAN
NC score	0.064704 (rank : 708)	θ value	5.27518 (rank : 595)
Query Neighborhood Hits	671	Target Neighborhood Hits	192	Shared Neighborhood Hits	116
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

DCBD2_HUMAN
NC score	0.064202 (rank : 709)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	671	Target Neighborhood Hits	118	Shared Neighborhood Hits	31
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

FCN3_HUMAN
NC score	0.064200 (rank : 710)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	671	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

GP123_HUMAN
NC score	0.063265 (rank : 711)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	671	Target Neighborhood Hits	120	Shared Neighborhood Hits	25
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

FCN2_HUMAN
NC score	0.063180 (rank : 712)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	671	Target Neighborhood Hits	122	Shared Neighborhood Hits	11
SwissProt Accessions	Q15485, Q9UC57	Gene names	FCN2
Domain Architecture
Description	Ficolin-2 precursor (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin B) (Serum lectin p35) (EBP-37) (Hucolin) (L- Ficolin).

LRP11_HUMAN
NC score	0.062708 (rank : 713)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	671	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q86VZ4, Q5VYC0, Q96SN6	Gene names	LRP11
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 11 precursor.

KREM2_HUMAN
NC score	0.062581 (rank : 714)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	671	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

GP125_HUMAN
NC score	0.062507 (rank : 715)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	671	Target Neighborhood Hits	327	Shared Neighborhood Hits	30
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

CDN2B_HUMAN
NC score	0.062242 (rank : 716)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	671	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

GP124_MOUSE
NC score	0.061998 (rank : 717)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	671	Target Neighborhood Hits	423	Shared Neighborhood Hits	39
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

CD2A1_MOUSE
NC score	0.061844 (rank : 718)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	671	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

DMBT1_HUMAN
NC score	0.061426 (rank : 719)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	671	Target Neighborhood Hits	152	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

WFDC2_HUMAN
NC score	0.061189 (rank : 720)	θ value	θ > 10 (rank : 931)
Query Neighborhood Hits	671	Target Neighborhood Hits	73	Shared Neighborhood Hits	49
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

THYG_MOUSE
NC score	0.061171 (rank : 721)	θ value	3.0926 (rank : 573)
Query Neighborhood Hits	671	Target Neighborhood Hits	161	Shared Neighborhood Hits	79
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

DCBD2_MOUSE
NC score	0.060962 (rank : 722)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	671	Target Neighborhood Hits	113	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

ANGL7_MOUSE
NC score	0.060832 (rank : 723)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	671	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

TR10B_MOUSE
NC score	0.060824 (rank : 724)	θ value	θ > 10 (rank : 924)
Query Neighborhood Hits	671	Target Neighborhood Hits	76	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

ATS7_HUMAN
NC score	0.060724 (rank : 725)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	671	Target Neighborhood Hits	169	Shared Neighborhood Hits	94
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ANGL6_MOUSE
NC score	0.060619 (rank : 726)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	671	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0Z6	Gene names	Angptl6, Agf
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor).

ANGL7_HUMAN
NC score	0.060588 (rank : 727)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	671	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	O43827, Q4ZGK4	Gene names	ANGPTL7, CDT6
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7) (Angiopoietin-like factor) (Cornea-derived transcript 6 protein).

FGL1_HUMAN
NC score	0.060446 (rank : 728)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	671	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q08830, Q4PJH9, Q96KW6, Q96QM6	Gene names	FGL1, HFREP1
Domain Architecture
Description	Fibrinogen-like protein 1 precursor (Hepatocyte-derived fibrinogen- related protein 1) (HFREP-1) (Hepassocin) (HP-041).

HBEGF_MOUSE
NC score	0.059995 (rank : 729)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	671	Target Neighborhood Hits	48	Shared Neighborhood Hits	41
SwissProt Accessions	Q06186	Gene names	Hbegf, Dtr, Hegfl
Domain Architecture	No domain graphic available
Description	Heparin-binding EGF-like growth factor precursor (HB-EGF) (HBEGF).

ANGL5_HUMAN
NC score	0.059806 (rank : 730)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	671	Target Neighborhood Hits	56	Shared Neighborhood Hits	9
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

KRA63_HUMAN
NC score	0.059739 (rank : 731)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	671	Target Neighborhood Hits	12	Shared Neighborhood Hits	7
SwissProt Accessions	Q3LI67	Gene names	KRTAP6-3, KAP6.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-3.

KREM1_MOUSE
NC score	0.059699 (rank : 732)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	671	Target Neighborhood Hits	92	Shared Neighborhood Hits	34
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

FGL2_MOUSE
NC score	0.059383 (rank : 733)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

FCN1_HUMAN
NC score	0.059372 (rank : 734)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	671	Target Neighborhood Hits	147	Shared Neighborhood Hits	14
SwissProt Accessions	O00602, Q92596	Gene names	FCN1
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

KREM1_HUMAN
NC score	0.059327 (rank : 735)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	671	Target Neighborhood Hits	90	Shared Neighborhood Hits	32
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

THRB_HUMAN
NC score	0.059232 (rank : 736)	θ value	θ > 10 (rank : 894)
Query Neighborhood Hits	671	Target Neighborhood Hits	196	Shared Neighborhood Hits	38
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

FIBA_HUMAN
NC score	0.059092 (rank : 737)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	671	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

ANGL6_HUMAN
NC score	0.058876 (rank : 738)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	671	Target Neighborhood Hits	70	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

TMG4_MOUSE
NC score	0.058849 (rank : 739)	θ value	θ > 10 (rank : 902)
Query Neighborhood Hits	671	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BGN6, Q8BM25	Gene names	Prrg4, Tmg4
Domain Architecture
Description	Transmembrane gamma-carboxyglutamic acid protein 4 precursor (Proline- rich Gla protein 4) (Proline-rich gamma-carboxyglutamic acid protein 4).

GP124_HUMAN
NC score	0.058846 (rank : 740)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	671	Target Neighborhood Hits	304	Shared Neighborhood Hits	30
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

FGL2_HUMAN
NC score	0.058733 (rank : 741)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	671	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q14314	Gene names	FGL2
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (pT49).

TMPS9_HUMAN
NC score	0.058695 (rank : 742)	θ value	θ > 10 (rank : 909)
Query Neighborhood Hits	671	Target Neighborhood Hits	276	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

FCN1_MOUSE
NC score	0.058599 (rank : 743)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	671	Target Neighborhood Hits	173	Shared Neighborhood Hits	16
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

SPON1_MOUSE
NC score	0.058336 (rank : 744)	θ value	θ > 10 (rank : 891)
Query Neighborhood Hits	671	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

TMPS9_MOUSE
NC score	0.058329 (rank : 745)	θ value	θ > 10 (rank : 910)
Query Neighborhood Hits	671	Target Neighborhood Hits	296	Shared Neighborhood Hits	73
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

KR211_HUMAN
NC score	0.058168 (rank : 746)	θ value	0.62314 (rank : 485)
Query Neighborhood Hits	671	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q3LI58	Gene names	KRTAP21-1, KAP21.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 21-1.

GP125_MOUSE
NC score	0.058022 (rank : 747)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	671	Target Neighborhood Hits	329	Shared Neighborhood Hits	29
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

CFAB_HUMAN
NC score	0.057959 (rank : 748)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	671	Target Neighborhood Hits	251	Shared Neighborhood Hits	57
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

TR11B_HUMAN
NC score	0.057825 (rank : 749)	θ value	6.88961 (rank : 645)
Query Neighborhood Hits	671	Target Neighborhood Hits	92	Shared Neighborhood Hits	59
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR1B_MOUSE
NC score	0.057635 (rank : 750)	θ value	θ > 10 (rank : 916)
Query Neighborhood Hits	671	Target Neighborhood Hits	123	Shared Neighborhood Hits	62
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

THRB_MOUSE
NC score	0.057629 (rank : 751)	θ value	θ > 10 (rank : 895)
Query Neighborhood Hits	671	Target Neighborhood Hits	195	Shared Neighborhood Hits	38
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TR11B_MOUSE
NC score	0.057143 (rank : 752)	θ value	8.99809 (rank : 670)
Query Neighborhood Hits	671	Target Neighborhood Hits	95	Shared Neighborhood Hits	60
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

KREM2_MOUSE
NC score	0.056871 (rank : 753)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	671	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

ANGL2_MOUSE
NC score	0.056800 (rank : 754)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	671	Target Neighborhood Hits	108	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

FIBB_HUMAN
NC score	0.056774 (rank : 755)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	671	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	P02675	Gene names	FGB
Domain Architecture
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

FIBB_MOUSE
NC score	0.056708 (rank : 756)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	671	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0E8, Q91ZP1	Gene names	Fgb
Domain Architecture	No domain graphic available
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

ANGL2_HUMAN
NC score	0.056664 (rank : 757)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	671	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

CO2_HUMAN
NC score	0.056634 (rank : 758)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	671	Target Neighborhood Hits	258	Shared Neighborhood Hits	62
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

GP179_HUMAN
NC score	0.056587 (rank : 759)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	671	Target Neighborhood Hits	372	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

ANGP4_HUMAN
NC score	0.056576 (rank : 760)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	671	Target Neighborhood Hits	187	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

CO2_MOUSE
NC score	0.056533 (rank : 761)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	671	Target Neighborhood Hits	250	Shared Neighborhood Hits	61
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

EPHB6_HUMAN
NC score	0.056512 (rank : 762)	θ value	0.813845 (rank : 494)
Query Neighborhood Hits	671	Target Neighborhood Hits	912	Shared Neighborhood Hits	112
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

ASTL_HUMAN
NC score	0.056460 (rank : 763)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	671	Target Neighborhood Hits	252	Shared Neighborhood Hits	19
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

EPHB4_MOUSE
NC score	0.056456 (rank : 764)	θ value	0.21417 (rank : 437)
Query Neighborhood Hits	671	Target Neighborhood Hits	1013	Shared Neighborhood Hits	135
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

ATS16_HUMAN
NC score	0.056437 (rank : 765)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	671	Target Neighborhood Hits	208	Shared Neighborhood Hits	121
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ANGL1_MOUSE
NC score	0.056131 (rank : 766)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	671	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q640P2, Q3UQL1, Q9CZ81	Gene names	Angptl1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1).

ERBB3_HUMAN
NC score	0.056067 (rank : 767)	θ value	0.00228821 (rank : 335)
Query Neighborhood Hits	671	Target Neighborhood Hits	918	Shared Neighborhood Hits	132
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

GLU2B_HUMAN
NC score	0.055968 (rank : 768)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	671	Target Neighborhood Hits	377	Shared Neighborhood Hits	39
SwissProt Accessions	P14314, Q96BU9, Q96D06, Q9P0W9	Gene names	PRKCSH, G19P1
Domain Architecture	No domain graphic available
Description	Glucosidase 2 subunit beta precursor (Glucosidase II subunit beta) (Protein kinase C substrate, 60.1 kDa protein, heavy chain) (PKCSH) (80K-H protein).

INSR_HUMAN
NC score	0.055858 (rank : 769)	θ value	0.0193708 (rank : 374)
Query Neighborhood Hits	671	Target Neighborhood Hits	963	Shared Neighborhood Hits	139
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

SPON1_HUMAN
NC score	0.055662 (rank : 770)	θ value	θ > 10 (rank : 890)
Query Neighborhood Hits	671	Target Neighborhood Hits	117	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

ANGL1_HUMAN
NC score	0.055658 (rank : 771)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	671	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	O95841, Q5T5Z5	Gene names	ANGPTL1, ANG3, ANGPT3, ARP1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1) (Angiopoietin-3) (ANG-3).

CR001_HUMAN
NC score	0.055650 (rank : 772)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	671	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	O15165, O15166, O15167, O15168, Q6NXP3	Gene names	C18orf1
Domain Architecture
Description	Protein C18orf1.

IGF1R_MOUSE
NC score	0.055392 (rank : 773)	θ value	0.0736092 (rank : 403)
Query Neighborhood Hits	671	Target Neighborhood Hits	973	Shared Neighborhood Hits	149
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

CO6A3_HUMAN
NC score	0.055341 (rank : 774)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	671	Target Neighborhood Hits	317	Shared Neighborhood Hits	31
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

SEM5A_HUMAN
NC score	0.055239 (rank : 775)	θ value	0.00509761 (rank : 349)
Query Neighborhood Hits	671	Target Neighborhood Hits	177	Shared Neighborhood Hits	71
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

CDN2B_MOUSE
NC score	0.055059 (rank : 776)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	671	Target Neighborhood Hits	201	Shared Neighborhood Hits	8
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

ANGP1_HUMAN
NC score	0.054942 (rank : 777)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	671	Target Neighborhood Hits	254	Shared Neighborhood Hits	11
SwissProt Accessions	Q15389	Gene names	ANGPT1, KIAA0003
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANR38_MOUSE
NC score	0.054902 (rank : 778)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	671	Target Neighborhood Hits	512	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

HPT_HUMAN
NC score	0.054881 (rank : 779)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	671	Target Neighborhood Hits	184	Shared Neighborhood Hits	37
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

CR001_MOUSE
NC score	0.054873 (rank : 780)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	671	Target Neighborhood Hits	67	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BWJ4	Gene names	D18Ertd653e
Domain Architecture	No domain graphic available
Description	Protein C18orf1 homolog.

ANGL4_MOUSE
NC score	0.054840 (rank : 781)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	671	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1P8, Q78ZJ9, Q9JHX7, Q9JLX7	Gene names	Angptl4, Farp, Fiaf, Ng27
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Fasting- induced adipose factor) (Secreted protein Bk89) (425O18-1).

SDK2_MOUSE
NC score	0.054812 (rank : 782)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	671	Target Neighborhood Hits	480	Shared Neighborhood Hits	54
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

ANGL3_MOUSE
NC score	0.054618 (rank : 783)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	671	Target Neighborhood Hits	306	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

HPTR_HUMAN
NC score	0.054524 (rank : 784)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	671	Target Neighborhood Hits	166	Shared Neighborhood Hits	34
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

ATS17_HUMAN
NC score	0.054472 (rank : 785)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	671	Target Neighborhood Hits	194	Shared Neighborhood Hits	100
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ANGL4_HUMAN
NC score	0.054264 (rank : 786)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	671	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

SPR2D_HUMAN
NC score	0.054061 (rank : 787)	θ value	6.88961 (rank : 639)
Query Neighborhood Hits	671	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

SDK1_HUMAN
NC score	0.053999 (rank : 788)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	671	Target Neighborhood Hits	511	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK1_MOUSE
NC score	0.053966 (rank : 789)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	671	Target Neighborhood Hits	495	Shared Neighborhood Hits	59
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

TMPS2_MOUSE
NC score	0.053654 (rank : 790)	θ value	θ > 10 (rank : 904)
Query Neighborhood Hits	671	Target Neighborhood Hits	243	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

HPT_MOUSE
NC score	0.053549 (rank : 791)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	671	Target Neighborhood Hits	178	Shared Neighborhood Hits	34
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

EPHA7_HUMAN
NC score	0.053548 (rank : 792)	θ value	1.38821 (rank : 519)
Query Neighborhood Hits	671	Target Neighborhood Hits	1053	Shared Neighborhood Hits	148
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

ATS12_MOUSE
NC score	0.053444 (rank : 793)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	671	Target Neighborhood Hits	220	Shared Neighborhood Hits	111
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ANGP4_MOUSE
NC score	0.053431 (rank : 794)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	671	Target Neighborhood Hits	220	Shared Neighborhood Hits	9
SwissProt Accessions	Q9WVH6	Gene names	Angpt4, Agpt4, Ang3
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ANR38_HUMAN
NC score	0.053364 (rank : 795)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	671	Target Neighborhood Hits	443	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ATS16_MOUSE
NC score	0.052891 (rank : 796)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	671	Target Neighborhood Hits	179	Shared Neighborhood Hits	109
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS6_HUMAN
NC score	0.052875 (rank : 797)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	671	Target Neighborhood Hits	141	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ANGP1_MOUSE
NC score	0.052828 (rank : 798)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	671	Target Neighborhood Hits	252	Shared Neighborhood Hits	10
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

SDK2_HUMAN
NC score	0.052817 (rank : 799)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	671	Target Neighborhood Hits	495	Shared Neighborhood Hits	56
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

ATS18_HUMAN
NC score	0.052748 (rank : 800)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	671	Target Neighborhood Hits	169	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

TRI42_MOUSE
NC score	0.052571 (rank : 801)	θ value	0.813845 (rank : 501)
Query Neighborhood Hits	671	Target Neighborhood Hits	316	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

NEO1_HUMAN
NC score	0.052250 (rank : 802)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	671	Target Neighborhood Hits	530	Shared Neighborhood Hits	57
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

EPHA1_HUMAN
NC score	0.052238 (rank : 803)	θ value	0.0736092 (rank : 401)
Query Neighborhood Hits	671	Target Neighborhood Hits	997	Shared Neighborhood Hits	131
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

FIBG_MOUSE
NC score	0.052038 (rank : 804)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	671	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCM7, Q8WUR3, Q91ZP0	Gene names	Fgg
Domain Architecture	No domain graphic available
Description	Fibrinogen gamma chain precursor.

TMPS3_MOUSE
NC score	0.052014 (rank : 805)	θ value	θ > 10 (rank : 906)
Query Neighborhood Hits	671	Target Neighborhood Hits	239	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

ANR15_HUMAN
NC score	0.051937 (rank : 806)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	671	Target Neighborhood Hits	478	Shared Neighborhood Hits	9
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

NEO1_MOUSE
NC score	0.051693 (rank : 807)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	671	Target Neighborhood Hits	523	Shared Neighborhood Hits	56
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

ATS1_HUMAN
NC score	0.051631 (rank : 808)	θ value	0.62314 (rank : 481)
Query Neighborhood Hits	671	Target Neighborhood Hits	159	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UHI8, Q9NSJ8, Q9P2K0, Q9UH83, Q9UP80	Gene names	ADAMTS1, KIAA1346, METH1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).

ASB16_MOUSE
NC score	0.051565 (rank : 809)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	671	Target Neighborhood Hits	306	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

FIBG_HUMAN
NC score	0.051506 (rank : 810)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	671	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	P02679, P04469, P04470, Q96A14, Q96KJ3	Gene names	FGG
Domain Architecture
Description	Fibrinogen gamma chain precursor.

SEM5B_MOUSE
NC score	0.051462 (rank : 811)	θ value	5.27518 (rank : 611)
Query Neighborhood Hits	671	Target Neighborhood Hits	190	Shared Neighborhood Hits	75
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

INSR_MOUSE
NC score	0.051400 (rank : 812)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	671	Target Neighborhood Hits	968	Shared Neighborhood Hits	136
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

TMPS3_HUMAN
NC score	0.051365 (rank : 813)	θ value	θ > 10 (rank : 905)
Query Neighborhood Hits	671	Target Neighborhood Hits	245	Shared Neighborhood Hits	62
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TR10A_HUMAN
NC score	0.051121 (rank : 814)	θ value	θ > 10 (rank : 923)
Query Neighborhood Hits	671	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

WISP3_HUMAN
NC score	0.050980 (rank : 815)	θ value	θ > 10 (rank : 932)
Query Neighborhood Hits	671	Target Neighborhood Hits	87	Shared Neighborhood Hits	50
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ATS1_MOUSE
NC score	0.050979 (rank : 816)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	671	Target Neighborhood Hits	158	Shared Neighborhood Hits	95
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS12_HUMAN
NC score	0.050869 (rank : 817)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	671	Target Neighborhood Hits	251	Shared Neighborhood Hits	106
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

TMPS2_HUMAN
NC score	0.050635 (rank : 818)	θ value	θ > 10 (rank : 903)
Query Neighborhood Hits	671	Target Neighborhood Hits	252	Shared Neighborhood Hits	59
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

GP2_HUMAN
NC score	0.050631 (rank : 819)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	671	Target Neighborhood Hits	34	Shared Neighborhood Hits	13
SwissProt Accessions	P55259, Q13338, Q9UIF1	Gene names	GP2
Domain Architecture
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2) (ZAP75).

SRPX_MOUSE
NC score	0.050603 (rank : 820)	θ value	θ > 10 (rank : 892)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	31
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

ASTL_MOUSE
NC score	0.050596 (rank : 821)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	671	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ERBB3_MOUSE
NC score	0.050367 (rank : 822)	θ value	0.00228821 (rank : 336)
Query Neighborhood Hits	671	Target Neighborhood Hits	898	Shared Neighborhood Hits	111
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ATL2_HUMAN
NC score	0.050351 (rank : 823)	θ value	2.36792 (rank : 545)
Query Neighborhood Hits	671	Target Neighborhood Hits	125	Shared Neighborhood Hits	62
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

IGF1R_HUMAN
NC score	0.050282 (rank : 824)	θ value	0.21417 (rank : 438)
Query Neighborhood Hits	671	Target Neighborhood Hits	977	Shared Neighborhood Hits	150
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IMPG1_HUMAN
NC score	0.049679 (rank : 825)	θ value	0.21417 (rank : 439)
Query Neighborhood Hits	671	Target Neighborhood Hits	75	Shared Neighborhood Hits	26
SwissProt Accessions	Q17R60, O43686, O95094, Q9BWZ1	Gene names	IMPG1, IPM150, SPACR
Domain Architecture	No domain graphic available
Description	Interphotoreceptor matrix proteoglycan 1 precursor (Interphotoreceptor matrix proteoglycan of 150 kDa) (IPM-150) (Sialoprotein associated with cones and rods).

DKK2_MOUSE
NC score	0.048493 (rank : 826)	θ value	0.00869519 (rank : 357)
Query Neighborhood Hits	671	Target Neighborhood Hits	34	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYZ8	Gene names	Dkk2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (mDkk-2).

ERBB4_HUMAN
NC score	0.048422 (rank : 827)	θ value	0.813845 (rank : 495)
Query Neighborhood Hits	671	Target Neighborhood Hits	910	Shared Neighborhood Hits	111
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

EPHB6_MOUSE
NC score	0.048350 (rank : 828)	θ value	0.163984 (rank : 428)
Query Neighborhood Hits	671	Target Neighborhood Hits	906	Shared Neighborhood Hits	95
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

CILP1_HUMAN
NC score	0.048301 (rank : 829)	θ value	0.0431538 (rank : 392)
Query Neighborhood Hits	671	Target Neighborhood Hits	266	Shared Neighborhood Hits	48
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

DKK2_HUMAN
NC score	0.048232 (rank : 830)	θ value	0.0736092 (rank : 400)
Query Neighborhood Hits	671	Target Neighborhood Hits	31	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBU2, Q9UIU3	Gene names	DKK2
Domain Architecture
Description	Dickkopf-related protein 2 precursor (Dkk-2) (Dickkopf-2) (hDkk-2).

SEM5B_HUMAN
NC score	0.046971 (rank : 831)	θ value	6.88961 (rank : 638)
Query Neighborhood Hits	671	Target Neighborhood Hits	178	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

EPHA1_MOUSE
NC score	0.046876 (rank : 832)	θ value	0.279714 (rank : 448)
Query Neighborhood Hits	671	Target Neighborhood Hits	958	Shared Neighborhood Hits	116
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHAA_HUMAN
NC score	0.046621 (rank : 833)	θ value	1.81305 (rank : 533)
Query Neighborhood Hits	671	Target Neighborhood Hits	960	Shared Neighborhood Hits	94
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

ATS8_HUMAN
NC score	0.046597 (rank : 834)	θ value	8.99809 (rank : 648)
Query Neighborhood Hits	671	Target Neighborhood Hits	145	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UP79, Q9NZS0	Gene names	ADAMTS8, METH2
Domain Architecture
Description	ADAMTS-8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH- 8).

ATL2_MOUSE
NC score	0.045747 (rank : 835)	θ value	1.81305 (rank : 532)
Query Neighborhood Hits	671	Target Neighborhood Hits	137	Shared Neighborhood Hits	62
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

EGFR_HUMAN
NC score	0.045392 (rank : 836)	θ value	0.163984 (rank : 427)
Query Neighborhood Hits	671	Target Neighborhood Hits	939	Shared Neighborhood Hits	132
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

HYAL3_MOUSE
NC score	0.044869 (rank : 837)	θ value	5.27518 (rank : 602)
Query Neighborhood Hits	671	Target Neighborhood Hits	44	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

EPHA2_HUMAN
NC score	0.044864 (rank : 838)	θ value	1.38821 (rank : 518)
Query Neighborhood Hits	671	Target Neighborhood Hits	1021	Shared Neighborhood Hits	107
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA7_MOUSE
NC score	0.044376 (rank : 839)	θ value	0.62314 (rank : 484)
Query Neighborhood Hits	671	Target Neighborhood Hits	1025	Shared Neighborhood Hits	121
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

ATL3_HUMAN
NC score	0.043959 (rank : 840)	θ value	0.0330416 (rank : 383)
Query Neighborhood Hits	671	Target Neighborhood Hits	414	Shared Neighborhood Hits	86
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

CILP1_MOUSE
NC score	0.043005 (rank : 841)	θ value	0.0961366 (rank : 411)
Query Neighborhood Hits	671	Target Neighborhood Hits	282	Shared Neighborhood Hits	43
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

EGFR_MOUSE
NC score	0.042637 (rank : 842)	θ value	3.0926 (rank : 562)
Query Neighborhood Hits	671	Target Neighborhood Hits	927	Shared Neighborhood Hits	117
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

KAZD1_HUMAN
NC score	0.042131 (rank : 843)	θ value	0.365318 (rank : 466)
Query Neighborhood Hits	671	Target Neighborhood Hits	248	Shared Neighborhood Hits	49
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

EPHA3_HUMAN
NC score	0.041983 (rank : 844)	θ value	4.03905 (rank : 582)
Query Neighborhood Hits	671	Target Neighborhood Hits	1005	Shared Neighborhood Hits	107
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

SEM5A_MOUSE
NC score	0.041798 (rank : 845)	θ value	0.0252991 (rank : 382)
Query Neighborhood Hits	671	Target Neighborhood Hits	162	Shared Neighborhood Hits	53
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ERBB2_HUMAN
NC score	0.041428 (rank : 846)	θ value	0.163984 (rank : 429)
Query Neighborhood Hits	671	Target Neighborhood Hits	1073	Shared Neighborhood Hits	107
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

HTRA1_HUMAN
NC score	0.040707 (rank : 847)	θ value	4.03905 (rank : 585)
Query Neighborhood Hits	671	Target Neighborhood Hits	155	Shared Neighborhood Hits	67
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HYAL3_HUMAN
NC score	0.040562 (rank : 848)	θ value	8.99809 (rank : 658)
Query Neighborhood Hits	671	Target Neighborhood Hits	45	Shared Neighborhood Hits	36
SwissProt Accessions	O43820, O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9	Gene names	HYAL3, LUCA3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3) (LUCA-3).

ENPP2_MOUSE
NC score	0.040433 (rank : 849)	θ value	0.365318 (rank : 464)
Query Neighborhood Hits	671	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	Q9R1E6, Q99LG9	Gene names	Enpp2, Npps2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

EPHB2_MOUSE
NC score	0.040355 (rank : 850)	θ value	1.81305 (rank : 535)
Query Neighborhood Hits	671	Target Neighborhood Hits	982	Shared Neighborhood Hits	100
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB2_HUMAN
NC score	0.040321 (rank : 851)	θ value	1.81305 (rank : 534)
Query Neighborhood Hits	671	Target Neighborhood Hits	983	Shared Neighborhood Hits	100
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

F13B_MOUSE
NC score	0.040082 (rank : 852)	θ value	8.99809 (rank : 656)
Query Neighborhood Hits	671	Target Neighborhood Hits	93	Shared Neighborhood Hits	40
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

ERBB2_MOUSE
NC score	0.040029 (rank : 853)	θ value	0.00665767 (rank : 351)
Query Neighborhood Hits	671	Target Neighborhood Hits	918	Shared Neighborhood Hits	95
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

EPHB1_HUMAN
NC score	0.040011 (rank : 854)	θ value	0.279714 (rank : 449)
Query Neighborhood Hits	671	Target Neighborhood Hits	988	Shared Neighborhood Hits	110
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHB3_HUMAN
NC score	0.038290 (rank : 855)	θ value	0.47712 (rank : 476)
Query Neighborhood Hits	671	Target Neighborhood Hits	996	Shared Neighborhood Hits	91
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

SPY4_MOUSE
NC score	0.037336 (rank : 856)	θ value	5.27518 (rank : 613)
Query Neighborhood Hits	671	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WTP2, Q9QXV7	Gene names	Spry4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

TYRP2_HUMAN
NC score	0.037236 (rank : 857)	θ value	1.81305 (rank : 544)
Query Neighborhood Hits	671	Target Neighborhood Hits	42	Shared Neighborhood Hits	34
SwissProt Accessions	P40126	Gene names	DCT, TYRP2
Domain Architecture
Description	L-dopachrome tautomerase precursor (EC 5.3.3.12) (DT) (DCT) (L- dopachrome delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2).

SPRC_MOUSE
NC score	0.036949 (rank : 858)	θ value	4.03905 (rank : 591)
Query Neighborhood Hits	671	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

HTRA3_MOUSE
NC score	0.036226 (rank : 859)	θ value	4.03905 (rank : 586)
Query Neighborhood Hits	671	Target Neighborhood Hits	156	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

EPHA5_HUMAN
NC score	0.036071 (rank : 860)	θ value	6.88961 (rank : 623)
Query Neighborhood Hits	671	Target Neighborhood Hits	1009	Shared Neighborhood Hits	83
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

EPHB3_MOUSE
NC score	0.035778 (rank : 861)	θ value	0.0736092 (rank : 402)
Query Neighborhood Hits	671	Target Neighborhood Hits	996	Shared Neighborhood Hits	87
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

TRI42_HUMAN
NC score	0.035048 (rank : 862)	θ value	3.0926 (rank : 575)
Query Neighborhood Hits	671	Target Neighborhood Hits	283	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

HTRA3_HUMAN
NC score	0.035022 (rank : 863)	θ value	8.99809 (rank : 657)
Query Neighborhood Hits	671	Target Neighborhood Hits	152	Shared Neighborhood Hits	55
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

TYRO_HUMAN
NC score	0.034462 (rank : 864)	θ value	1.81305 (rank : 543)
Query Neighborhood Hits	671	Target Neighborhood Hits	35	Shared Neighborhood Hits	22
SwissProt Accessions	P14679, Q15675, Q15676, Q15680, Q8TAK4, Q9BYY0, Q9BZX1	Gene names	TYR
Domain Architecture
Description	Tyrosinase precursor (EC 1.14.18.1) (Monophenol monooxygenase) (Tumor rejection antigen AB) (SK29-AB) (LB24-AB).

ENPP2_HUMAN
NC score	0.031965 (rank : 865)	θ value	0.813845 (rank : 493)
Query Neighborhood Hits	671	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	Q13822, Q13827, Q15117	Gene names	ENPP2, ATX, PDNP2
Domain Architecture
Description	Ectonucleotide pyrophosphatase/phosphodiesterase 2 (E-NPP 2) (Phosphodiesterase I/nucleotide pyrophosphatase 2) (Phosphodiesterase I alpha) (PD-Ialpha) (Autotaxin) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (EC 3.6.1.9) (NPPase)].

HTRA1_MOUSE
NC score	0.031939 (rank : 866)	θ value	0.813845 (rank : 496)
Query Neighborhood Hits	671	Target Neighborhood Hits	140	Shared Neighborhood Hits	53
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

KAZD1_MOUSE
NC score	0.031626 (rank : 867)	θ value	6.88961 (rank : 630)
Query Neighborhood Hits	671	Target Neighborhood Hits	281	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

DKK1_MOUSE
NC score	0.031211 (rank : 868)	θ value	2.36792 (rank : 548)
Query Neighborhood Hits	671	Target Neighborhood Hits	28	Shared Neighborhood Hits	16
SwissProt Accessions	O54908	Gene names	Dkk1
Domain Architecture
Description	Dickkopf-related protein 1 precursor (Dkk-1) (Dickkopf-1) (mDkk-1).

EPHA8_MOUSE
NC score	0.030668 (rank : 869)	θ value	0.47712 (rank : 475)
Query Neighborhood Hits	671	Target Neighborhood Hits	969	Shared Neighborhood Hits	71
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

IBP6_MOUSE
NC score	0.030003 (rank : 870)	θ value	1.81305 (rank : 537)
Query Neighborhood Hits	671	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP1_MOUSE
NC score	0.029762 (rank : 871)	θ value	2.36792 (rank : 550)
Query Neighborhood Hits	671	Target Neighborhood Hits	97	Shared Neighborhood Hits	45
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

KR192_HUMAN
NC score	0.029501 (rank : 872)	θ value	6.88961 (rank : 631)
Query Neighborhood Hits	671	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q3LHN2	Gene names	KRTAP19-2, KAP19.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 19-2.

CO5A2_HUMAN
NC score	0.029104 (rank : 873)	θ value	1.38821 (rank : 515)
Query Neighborhood Hits	671	Target Neighborhood Hits	760	Shared Neighborhood Hits	78
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

DKK1_HUMAN
NC score	0.028551 (rank : 874)	θ value	1.06291 (rank : 505)
Query Neighborhood Hits	671	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	O94907	Gene names	DKK1
Domain Architecture
Description	Dickkopf-related protein 1 precursor (Dkk-1) (Dickkopf-1) (hDkk-1) (SK).

EPHA8_HUMAN
NC score	0.028420 (rank : 875)	θ value	5.27518 (rank : 598)
Query Neighborhood Hits	671	Target Neighborhood Hits	956	Shared Neighborhood Hits	65
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

TICN1_MOUSE
NC score	0.028276 (rank : 876)	θ value	8.99809 (rank : 669)
Query Neighborhood Hits	671	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

FAM5B_HUMAN
NC score	0.026924 (rank : 877)	θ value	6.88961 (rank : 627)
Query Neighborhood Hits	671	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

FAM5B_MOUSE
NC score	0.026713 (rank : 878)	θ value	5.27518 (rank : 599)
Query Neighborhood Hits	671	Target Neighborhood Hits	51	Shared Neighborhood Hits	36
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

CO1A1_MOUSE
NC score	0.025860 (rank : 879)	θ value	8.99809 (rank : 651)
Query Neighborhood Hits	671	Target Neighborhood Hits	457	Shared Neighborhood Hits	62
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

SPY4_HUMAN
NC score	0.025146 (rank : 880)	θ value	6.88961 (rank : 640)
Query Neighborhood Hits	671	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	Q9C004, Q6QIX2, Q9C003	Gene names	SPRY4
Domain Architecture
Description	Sprouty homolog 4 (Spry-4).

DKK4_MOUSE
NC score	0.024069 (rank : 881)	θ value	4.03905 (rank : 580)
Query Neighborhood Hits	671	Target Neighborhood Hits	22	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VEJ3	Gene names	Dkk4
Domain Architecture	No domain graphic available
Description	Dickkopf-related protein 4 precursor (Dkk-4) (Dickkopf-4).

IBP1_HUMAN
NC score	0.024066 (rank : 882)	θ value	3.0926 (rank : 564)
Query Neighborhood Hits	671	Target Neighborhood Hits	67	Shared Neighborhood Hits	39
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

EZH1_MOUSE
NC score	0.023922 (rank : 883)	θ value	6.88961 (rank : 626)
Query Neighborhood Hits	671	Target Neighborhood Hits	126	Shared Neighborhood Hits	55
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_HUMAN
NC score	0.022939 (rank : 884)	θ value	6.88961 (rank : 625)
Query Neighborhood Hits	671	Target Neighborhood Hits	121	Shared Neighborhood Hits	48
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

COGA1_HUMAN
NC score	0.022587 (rank : 885)	θ value	0.62314 (rank : 483)
Query Neighborhood Hits	671	Target Neighborhood Hits	345	Shared Neighborhood Hits	35
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

LTK_MOUSE
NC score	0.021864 (rank : 886)	θ value	5.27518 (rank : 605)
Query Neighborhood Hits	671	Target Neighborhood Hits	770	Shared Neighborhood Hits	42
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

CO3A1_HUMAN
NC score	0.021478 (rank : 887)	θ value	0.813845 (rank : 492)
Query Neighborhood Hits	671	Target Neighborhood Hits	452	Shared Neighborhood Hits	45
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

EZH2_MOUSE
NC score	0.020577 (rank : 888)	θ value	4.03905 (rank : 584)
Query Neighborhood Hits	671	Target Neighborhood Hits	86	Shared Neighborhood Hits	34
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EMID2_MOUSE
NC score	0.020577 (rank : 889)	θ value	4.03905 (rank : 581)
Query Neighborhood Hits	671	Target Neighborhood Hits	201	Shared Neighborhood Hits	30
SwissProt Accessions	Q91VF6, Q8K4P3	Gene names	Emid2, Col26a, Col26a1, Emu2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

EZH2_HUMAN
NC score	0.019911 (rank : 890)	θ value	4.03905 (rank : 583)
Query Neighborhood Hits	671	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

VEGFD_HUMAN
NC score	0.018536 (rank : 891)	θ value	4.03905 (rank : 594)
Query Neighborhood Hits	671	Target Neighborhood Hits	48	Shared Neighborhood Hits	27
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

RON_HUMAN
NC score	0.016883 (rank : 892)	θ value	6.88961 (rank : 636)
Query Neighborhood Hits	671	Target Neighborhood Hits	842	Shared Neighborhood Hits	46
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

CN065_HUMAN
NC score	0.014476 (rank : 893)	θ value	2.36792 (rank : 547)
Query Neighborhood Hits	671	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N9R9	Gene names	C14orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf65.

BAMBI_HUMAN
NC score	0.014341 (rank : 894)	θ value	5.27518 (rank : 596)
Query Neighborhood Hits	671	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q13145	Gene names	BAMBI, NMA
Domain Architecture
Description	BMP and activin membrane-bound inhibitor homolog precursor (Putative transmembrane protein NMA) (Non-metastatic gene A protein).

RSN_HUMAN
NC score	0.013619 (rank : 895)	θ value	2.36792 (rank : 555)
Query Neighborhood Hits	671	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HD89, Q540D9	Gene names	RETN, FIZZ3, HXCP1, RSTN
Domain Architecture
Description	Resistin precursor (Cysteine-rich secreted protein FIZZ3) (Adipose tissue-specific secretory factor) (ADSF) (C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein) (Cysteine-rich secreted protein A12-alpha-like 2).

AXUD1_MOUSE
NC score	0.013219 (rank : 896)	θ value	2.36792 (rank : 546)
Query Neighborhood Hits	671	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	P59054	Gene names	Axud1, Taip3
Domain Architecture	No domain graphic available
Description	Axin-1 up-regulated gene 1 protein (TGF-beta-induced apoptosis protein 3) (TAIP-3).

MYCB2_HUMAN
NC score	0.012729 (rank : 897)	θ value	6.88961 (rank : 632)
Query Neighborhood Hits	671	Target Neighborhood Hits	390	Shared Neighborhood Hits	31
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

EMID2_HUMAN
NC score	0.012683 (rank : 898)	θ value	8.99809 (rank : 654)
Query Neighborhood Hits	671	Target Neighborhood Hits	226	Shared Neighborhood Hits	27
SwissProt Accessions	Q96A83	Gene names	EMID2, COL26A1, EMU2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XXVI) chain precursor (EMI domain-containing protein 2) (Protein Emu2) (Emilin and multimerin domain-containing protein 2).

SEPP1_HUMAN
NC score	0.012325 (rank : 899)	θ value	4.03905 (rank : 589)
Query Neighborhood Hits	671	Target Neighborhood Hits	28	Shared Neighborhood Hits	15
SwissProt Accessions	P49908, Q6PD59, Q6PI43, Q6PI87, Q6PJF9	Gene names	SEPP1, SELP
Domain Architecture
Description	Selenoprotein P precursor (SeP).

TECT2_MOUSE
NC score	0.010989 (rank : 900)	θ value	4.03905 (rank : 592)
Query Neighborhood Hits	671	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q2MV57, Q6PDZ5, Q8C0B3, Q9CXF5	Gene names	Tect2
Domain Architecture	No domain graphic available
Description	Tectonic-2 precursor.

CECR6_HUMAN
NC score	0.010890 (rank : 901)	θ value	1.38821 (rank : 514)
Query Neighborhood Hits	671	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BXQ6	Gene names	CECR6
Domain Architecture	No domain graphic available
Description	Cat eye syndrome critical region protein 6.

FBX38_MOUSE
NC score	0.010874 (rank : 902)	θ value	1.81305 (rank : 536)
Query Neighborhood Hits	671	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BMI0, Q8BTQ4, Q8C0H4	Gene names	Fbxo38
Domain Architecture	No domain graphic available
Description	F-box only protein 38 (Modulator of KLF7 activity) (MoKA).

HHCM_HUMAN
NC score	0.009939 (rank : 903)	θ value	3.0926 (rank : 563)
Query Neighborhood Hits	671	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q05877	Gene names
Domain Architecture	No domain graphic available
Description	Hepatocellular carcinoma protein HHCM (HHC(M)).

MYCB2_MOUSE
NC score	0.009744 (rank : 904)	θ value	6.88961 (rank : 633)
Query Neighborhood Hits	671	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

DB131_HUMAN
NC score	0.009314 (rank : 905)	θ value	6.88961 (rank : 622)
Query Neighborhood Hits	671	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P59861	Gene names	DEFB131, DEFB31
Domain Architecture	No domain graphic available
Description	Beta-defensin 131 precursor (Defensin, beta 131) (Beta-defensin 31) (DEFB-31).

PKHB2_HUMAN
NC score	0.008858 (rank : 906)	θ value	1.38821 (rank : 524)
Query Neighborhood Hits	671	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

SO2A1_MOUSE
NC score	0.008851 (rank : 907)	θ value	8.99809 (rank : 667)
Query Neighborhood Hits	671	Target Neighborhood Hits	51	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

TIAF1_HUMAN
NC score	0.007932 (rank : 908)	θ value	6.88961 (rank : 642)
Query Neighborhood Hits	671	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	O95411, Q6PEG2	Gene names	TIAF1
Domain Architecture	No domain graphic available
Description	TGFB1-induced anti-apoptotic factor 1 (12 kDa TGF-beta1-induced antiapoptotic factor).

TIAF1_MOUSE
NC score	0.007932 (rank : 909)	θ value	6.88961 (rank : 643)
Query Neighborhood Hits	671	Target Neighborhood Hits	3	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1S4	Gene names	Tiaf1
Domain Architecture	No domain graphic available
Description	TGFB1-induced anti-apoptotic factor 1 (12 kDa TGF-beta1-induced antiapoptotic factor).

SO2A1_HUMAN
NC score	0.007754 (rank : 910)	θ value	1.06291 (rank : 507)
Query Neighborhood Hits	671	Target Neighborhood Hits	40	Shared Neighborhood Hits	15
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

RP1L1_MOUSE
NC score	0.005226 (rank : 911)	θ value	5.27518 (rank : 608)
Query Neighborhood Hits	671	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

CB027_HUMAN
NC score	0.004969 (rank : 912)	θ value	8.99809 (rank : 650)
Query Neighborhood Hits	671	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q580R0, O43575, Q52M10, Q86XG2	Gene names	C2orf27
Domain Architecture	No domain graphic available
Description	Protein C2orf27.

TRI56_MOUSE
NC score	0.004430 (rank : 913)	θ value	3.0926 (rank : 576)
Query Neighborhood Hits	671	Target Neighborhood Hits	255	Shared Neighborhood Hits	14
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

SO2B1_MOUSE
NC score	0.004398 (rank : 914)	θ value	5.27518 (rank : 612)
Query Neighborhood Hits	671	Target Neighborhood Hits	37	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

HAIR_HUMAN
NC score	0.004119 (rank : 915)	θ value	6.88961 (rank : 628)
Query Neighborhood Hits	671	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

SO1A1_MOUSE
NC score	0.003442 (rank : 916)	θ value	3.0926 (rank : 571)
Query Neighborhood Hits	671	Target Neighborhood Hits	28	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SYN2_HUMAN
NC score	0.003043 (rank : 917)	θ value	1.38821 (rank : 526)
Query Neighborhood Hits	671	Target Neighborhood Hits	213	Shared Neighborhood Hits	8
SwissProt Accessions	Q92777	Gene names	SYN2
Domain Architecture
Description	Synapsin-2 (Synapsin II).

ACCN4_MOUSE
NC score	0.002088 (rank : 918)	θ value	6.88961 (rank : 618)
Query Neighborhood Hits	671	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TNS7, Q80XK4	Gene names	Accn4, Asic4
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 4 (Acid-sensing ion channel 4).

LY10_HUMAN
NC score	0.001911 (rank : 919)	θ value	4.03905 (rank : 587)
Query Neighborhood Hits	671	Target Neighborhood Hits	151	Shared Neighborhood Hits	7
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

RRMJ3_MOUSE
NC score	0.001450 (rank : 920)	θ value	5.27518 (rank : 609)
Query Neighborhood Hits	671	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

CAC1I_HUMAN
NC score	0.000924 (rank : 921)	θ value	0.47712 (rank : 473)
Query Neighborhood Hits	671	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

TBCD8_HUMAN
NC score	0.000889 (rank : 922)	θ value	5.27518 (rank : 614)
Query Neighborhood Hits	671	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	O95759, Q9UQ32	Gene names	TBC1D8, VRP
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (AD 3).

KRHB6_MOUSE
NC score	0.000209 (rank : 923)	θ value	5.27518 (rank : 603)
Query Neighborhood Hits	671	Target Neighborhood Hits	413	Shared Neighborhood Hits	28
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

LEG3_HUMAN
NC score	0.000051 (rank : 924)	θ value	5.27518 (rank : 604)
Query Neighborhood Hits	671	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	P17931, Q16005, Q96J47	Gene names	LGALS3, MAC2
Domain Architecture
Description	Galectin-3 (Galactose-specific lectin 3) (Mac-2 antigen) (IgE-binding protein) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Laminin-binding protein) (Lectin L-29) (L-31) (Galactoside-binding protein) (GALBP).

HCN2_MOUSE
NC score	-0.001166 (rank : 925)	θ value	6.88961 (rank : 629)
Query Neighborhood Hits	671	Target Neighborhood Hits	278	Shared Neighborhood Hits	7
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

EOMES_HUMAN
NC score	-0.001626 (rank : 926)	θ value	8.99809 (rank : 655)
Query Neighborhood Hits	671	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	O95936, Q8TAZ2, Q9UPM7	Gene names	EOMES, TBR2
Domain Architecture
Description	Eomesodermin homolog.

E2AK3_MOUSE
NC score	-0.003158 (rank : 927)	θ value	8.99809 (rank : 653)
Query Neighborhood Hits	671	Target Neighborhood Hits	851	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z2B5, Q9CTK8, Q9CWT5	Gene names	Eif2ak3, Pek, Perk
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase).

C1QT7_HUMAN
NC score	-0.003238 (rank : 928)	θ value	8.99809 (rank : 649)
Query Neighborhood Hits	671	Target Neighborhood Hits	119	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BXJ2	Gene names	C1QTNF7, CTRP7
Domain Architecture
Description	Complement C1q tumor necrosis factor-related protein 7 precursor.

RP1L1_HUMAN
NC score	-0.004806 (rank : 929)	θ value	6.88961 (rank : 637)
Query Neighborhood Hits	671	Target Neighborhood Hits	1072	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MICA1_MOUSE
NC score	-0.004853 (rank : 930)	θ value	5.27518 (rank : 606)
Query Neighborhood Hits	671	Target Neighborhood Hits	400	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDP3	Gene names	Mical1, Mical, Nical
Domain Architecture
Description	NEDD9-interacting protein with calponin homology and LIM domains (Molecule interacting with CasL protein 1).

BEGIN_HUMAN
NC score	-0.005246 (rank : 931)	θ value	6.88961 (rank : 620)
Query Neighborhood Hits	671	Target Neighborhood Hits	454	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

ZNF85_HUMAN
NC score	-0.015705 (rank : 932)	θ value	8.99809 (rank : 671)
Query Neighborhood Hits	671	Target Neighborhood Hits	770	Shared Neighborhood Hits	14
SwissProt Accessions	Q03923	Gene names	ZNF85
Domain Architecture
Description	Zinc finger protein 85 (Zinc finger protein HPF4) (HTF1).