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Network neighborhood for query Sequence : TNR21_MOUSE

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TNR21_MOUSE
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TNR21_HUMAN
θ value	0 (rank : 1)	NC score	0.985158 (rank : 2)
Query Neighborhood Hits	108	Target Neighborhood Hits	90	Shared Neighborhood Hits	65
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	108	Target Neighborhood Hits	108	Shared Neighborhood Hits	108
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TR11B_HUMAN
θ value	3.28125e-26 (rank : 3)	NC score	0.790015 (rank : 4)
Query Neighborhood Hits	108	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR6B_HUMAN
θ value	1.24688e-25 (rank : 4)	NC score	0.796757 (rank : 3)
Query Neighborhood Hits	108	Target Neighborhood Hits	103	Shared Neighborhood Hits	51
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TR11B_MOUSE
θ value	3.62785e-25 (rank : 5)	NC score	0.779565 (rank : 7)
Query Neighborhood Hits	108	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR1B_HUMAN
θ value	8.08199e-25 (rank : 6)	NC score	0.784331 (rank : 5)
Query Neighborhood Hits	108	Target Neighborhood Hits	127	Shared Neighborhood Hits	42
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1B_MOUSE
θ value	3.39556e-23 (rank : 7)	NC score	0.782962 (rank : 6)
Query Neighborhood Hits	108	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR5_MOUSE
θ value	8.65492e-19 (rank : 8)	NC score	0.726030 (rank : 9)
Query Neighborhood Hits	108	Target Neighborhood Hits	131	Shared Neighborhood Hits	47
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR3_HUMAN
θ value	8.10077e-17 (rank : 9)	NC score	0.726936 (rank : 8)
Query Neighborhood Hits	108	Target Neighborhood Hits	145	Shared Neighborhood Hits	51
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR3_MOUSE
θ value	3.40345e-15 (rank : 10)	NC score	0.721152 (rank : 10)
Query Neighborhood Hits	108	Target Neighborhood Hits	113	Shared Neighborhood Hits	55
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR9_HUMAN
θ value	4.44505e-15 (rank : 11)	NC score	0.682843 (rank : 13)
Query Neighborhood Hits	108	Target Neighborhood Hits	166	Shared Neighborhood Hits	59
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR11_HUMAN
θ value	1.09485e-13 (rank : 12)	NC score	0.679143 (rank : 14)
Query Neighborhood Hits	108	Target Neighborhood Hits	135	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR14_HUMAN
θ value	1.42992e-13 (rank : 13)	NC score	0.712452 (rank : 11)
Query Neighborhood Hits	108	Target Neighborhood Hits	149	Shared Neighborhood Hits	61
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR11_MOUSE
θ value	3.52202e-12 (rank : 14)	NC score	0.677876 (rank : 15)
Query Neighborhood Hits	108	Target Neighborhood Hits	121	Shared Neighborhood Hits	49
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR5_HUMAN
θ value	6.00763e-12 (rank : 15)	NC score	0.704663 (rank : 12)
Query Neighborhood Hits	108	Target Neighborhood Hits	102	Shared Neighborhood Hits	46
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR23_MOUSE
θ value	7.84624e-12 (rank : 16)	NC score	0.638717 (rank : 18)
Query Neighborhood Hits	108	Target Neighborhood Hits	114	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR16_HUMAN
θ value	2.52405e-10 (rank : 17)	NC score	0.598609 (rank : 21)
Query Neighborhood Hits	108	Target Neighborhood Hits	183	Shared Neighborhood Hits	61
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	2.52405e-10 (rank : 18)	NC score	0.610707 (rank : 20)
Query Neighborhood Hits	108	Target Neighborhood Hits	178	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR9_MOUSE
θ value	2.13673e-09 (rank : 19)	NC score	0.650133 (rank : 16)
Query Neighborhood Hits	108	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR8_HUMAN
θ value	8.11959e-09 (rank : 20)	NC score	0.593513 (rank : 22)
Query Neighborhood Hits	108	Target Neighborhood Hits	198	Shared Neighborhood Hits	53
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR22_MOUSE
θ value	3.08544e-08 (rank : 21)	NC score	0.632448 (rank : 19)
Query Neighborhood Hits	108	Target Neighborhood Hits	97	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR26_MOUSE
θ value	8.97725e-08 (rank : 22)	NC score	0.640093 (rank : 17)
Query Neighborhood Hits	108	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR8_MOUSE
θ value	3.41135e-07 (rank : 23)	NC score	0.514868 (rank : 27)
Query Neighborhood Hits	108	Target Neighborhood Hits	208	Shared Neighborhood Hits	50
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR1A_MOUSE
θ value	9.92553e-07 (rank : 24)	NC score	0.542818 (rank : 25)
Query Neighborhood Hits	108	Target Neighborhood Hits	131	Shared Neighborhood Hits	46
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR4_HUMAN
θ value	2.21117e-06 (rank : 25)	NC score	0.592399 (rank : 23)
Query Neighborhood Hits	108	Target Neighborhood Hits	152	Shared Neighborhood Hits	51
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TR10C_HUMAN
θ value	8.40245e-06 (rank : 26)	NC score	0.456082 (rank : 30)
Query Neighborhood Hits	108	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR1A_HUMAN
θ value	4.1701e-05 (rank : 27)	NC score	0.517615 (rank : 26)
Query Neighborhood Hits	108	Target Neighborhood Hits	121	Shared Neighborhood Hits	45
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR18_HUMAN
θ value	5.44631e-05 (rank : 28)	NC score	0.487901 (rank : 28)
Query Neighborhood Hits	108	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR25_HUMAN
θ value	7.1131e-05 (rank : 29)	NC score	0.469777 (rank : 29)
Query Neighborhood Hits	108	Target Neighborhood Hits	172	Shared Neighborhood Hits	61
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TR10A_HUMAN
θ value	0.000158464 (rank : 30)	NC score	0.413163 (rank : 33)
Query Neighborhood Hits	108	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_HUMAN
θ value	0.00020696 (rank : 31)	NC score	0.427244 (rank : 31)
Query Neighborhood Hits	108	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

SSPO_MOUSE
θ value	0.00298849 (rank : 32)	NC score	0.090160 (rank : 52)
Query Neighborhood Hits	108	Target Neighborhood Hits	800	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TNR4_MOUSE
θ value	0.0113563 (rank : 33)	NC score	0.545197 (rank : 24)
Query Neighborhood Hits	108	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

ZAN_MOUSE
θ value	0.0148317 (rank : 34)	NC score	0.126604 (rank : 47)
Query Neighborhood Hits	108	Target Neighborhood Hits	808	Shared Neighborhood Hits	66
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

EDAR_HUMAN
θ value	0.0252991 (rank : 35)	NC score	0.147417 (rank : 46)
Query Neighborhood Hits	108	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

TR10D_HUMAN
θ value	0.0252991 (rank : 36)	NC score	0.392746 (rank : 34)
Query Neighborhood Hits	108	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TSP4_HUMAN
θ value	0.0563607 (rank : 37)	NC score	0.040071 (rank : 125)
Query Neighborhood Hits	108	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

ADA17_HUMAN
θ value	0.0736092 (rank : 38)	NC score	0.049848 (rank : 120)
Query Neighborhood Hits	108	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

SCUB3_MOUSE
θ value	0.0736092 (rank : 39)	NC score	0.091339 (rank : 51)
Query Neighborhood Hits	108	Target Neighborhood Hits	442	Shared Neighborhood Hits	67
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
θ value	0.0961366 (rank : 40)	NC score	0.089744 (rank : 53)
Query Neighborhood Hits	108	Target Neighborhood Hits	428	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ADA17_MOUSE
θ value	0.125558 (rank : 41)	NC score	0.043364 (rank : 123)
Query Neighborhood Hits	108	Target Neighborhood Hits	201	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

FRAS1_HUMAN
θ value	0.125558 (rank : 42)	NC score	0.096287 (rank : 50)
Query Neighborhood Hits	108	Target Neighborhood Hits	759	Shared Neighborhood Hits	63
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MUC5B_HUMAN
θ value	0.125558 (rank : 43)	NC score	0.080246 (rank : 61)
Query Neighborhood Hits	108	Target Neighborhood Hits	1020	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

M3K12_MOUSE
θ value	0.163984 (rank : 44)	NC score	0.006350 (rank : 154)
Query Neighborhood Hits	108	Target Neighborhood Hits	957	Shared Neighborhood Hits	9
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

PCSK5_MOUSE
θ value	0.163984 (rank : 45)	NC score	0.122298 (rank : 48)
Query Neighborhood Hits	108	Target Neighborhood Hits	613	Shared Neighborhood Hits	75
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

LAMC2_MOUSE
θ value	0.21417 (rank : 46)	NC score	0.087589 (rank : 55)
Query Neighborhood Hits	108	Target Neighborhood Hits	614	Shared Neighborhood Hits	67
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

VWF_MOUSE
θ value	0.21417 (rank : 47)	NC score	0.083119 (rank : 58)
Query Neighborhood Hits	108	Target Neighborhood Hits	381	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ZAN_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.089393 (rank : 54)
Query Neighborhood Hits	108	Target Neighborhood Hits	679	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

FBN3_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.060980 (rank : 89)
Query Neighborhood Hits	108	Target Neighborhood Hits	543	Shared Neighborhood Hits	58
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LAMB2_HUMAN
θ value	0.365318 (rank : 50)	NC score	0.065446 (rank : 79)
Query Neighborhood Hits	108	Target Neighborhood Hits	692	Shared Neighborhood Hits	54
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

TNR18_MOUSE
θ value	0.365318 (rank : 51)	NC score	0.354207 (rank : 37)
Query Neighborhood Hits	108	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

LAMB2_MOUSE
θ value	0.47712 (rank : 52)	NC score	0.069110 (rank : 74)
Query Neighborhood Hits	108	Target Neighborhood Hits	722	Shared Neighborhood Hits	58
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC2_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.073346 (rank : 65)
Query Neighborhood Hits	108	Target Neighborhood Hits	715	Shared Neighborhood Hits	60
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

THYG_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.042559 (rank : 124)
Query Neighborhood Hits	108	Target Neighborhood Hits	161	Shared Neighborhood Hits	31
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

EPHA7_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.016434 (rank : 136)
Query Neighborhood Hits	108	Target Neighborhood Hits	1053	Shared Neighborhood Hits	41
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

TNR27_HUMAN
θ value	0.62314 (rank : 56)	NC score	0.243549 (rank : 40)
Query Neighborhood Hits	108	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

EPHA7_MOUSE
θ value	0.813845 (rank : 57)	NC score	0.014295 (rank : 142)
Query Neighborhood Hits	108	Target Neighborhood Hits	1025	Shared Neighborhood Hits	40
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHB2_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.014298 (rank : 141)
Query Neighborhood Hits	108	Target Neighborhood Hits	983	Shared Neighborhood Hits	32
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.813845 (rank : 59)	NC score	0.014264 (rank : 143)
Query Neighborhood Hits	108	Target Neighborhood Hits	982	Shared Neighborhood Hits	32
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

KIF5C_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.011835 (rank : 145)
Query Neighborhood Hits	108	Target Neighborhood Hits	974	Shared Neighborhood Hits	10
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LAMA5_MOUSE
θ value	0.813845 (rank : 61)	NC score	0.084296 (rank : 57)
Query Neighborhood Hits	108	Target Neighborhood Hits	828	Shared Neighborhood Hits	69
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

PODXL_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.039830 (rank : 126)
Query Neighborhood Hits	108	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

TENX_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.043499 (rank : 122)
Query Neighborhood Hits	108	Target Neighborhood Hits	789	Shared Neighborhood Hits	50
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

MEGF6_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.072696 (rank : 66)
Query Neighborhood Hits	108	Target Neighborhood Hits	671	Shared Neighborhood Hits	64
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

WIF1_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.050154 (rank : 118)
Query Neighborhood Hits	108	Target Neighborhood Hits	393	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

EGFR_HUMAN
θ value	1.38821 (rank : 66)	NC score	0.014407 (rank : 140)
Query Neighborhood Hits	108	Target Neighborhood Hits	939	Shared Neighborhood Hits	31
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

FOXE2_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.010409 (rank : 149)
Query Neighborhood Hits	108	Target Neighborhood Hits	236	Shared Neighborhood Hits	5
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

HCFC1_MOUSE
θ value	1.38821 (rank : 68)	NC score	0.021173 (rank : 133)
Query Neighborhood Hits	108	Target Neighborhood Hits	348	Shared Neighborhood Hits	11
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

STAB1_HUMAN
θ value	1.38821 (rank : 69)	NC score	0.065292 (rank : 80)
Query Neighborhood Hits	108	Target Neighborhood Hits	546	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

VWF_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.080453 (rank : 60)
Query Neighborhood Hits	108	Target Neighborhood Hits	396	Shared Neighborhood Hits	43
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

DRD2_HUMAN
θ value	1.81305 (rank : 71)	NC score	0.001399 (rank : 162)
Query Neighborhood Hits	108	Target Neighborhood Hits	774	Shared Neighborhood Hits	3
SwissProt Accessions	P14416, Q9NZR3, Q9UPA9	Gene names	DRD2
Domain Architecture
Description	D(2) dopamine receptor (Dopamine D2 receptor).

KIF5C_MOUSE
θ value	1.81305 (rank : 72)	NC score	0.009902 (rank : 151)
Query Neighborhood Hits	108	Target Neighborhood Hits	1040	Shared Neighborhood Hits	12
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

LAMA2_HUMAN
θ value	1.81305 (rank : 73)	NC score	0.063768 (rank : 82)
Query Neighborhood Hits	108	Target Neighborhood Hits	1092	Shared Neighborhood Hits	63
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

PCDGI_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.002346 (rank : 158)
Query Neighborhood Hits	108	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5F9, Q9Y5C5	Gene names	PCDHGB6
Domain Architecture
Description	Protocadherin gamma B6 precursor (PCDH-gamma-B6).

WIF1_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.049914 (rank : 119)
Query Neighborhood Hits	108	Target Neighborhood Hits	392	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

PALM_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.029853 (rank : 130)
Query Neighborhood Hits	108	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

SRRM2_MOUSE
θ value	2.36792 (rank : 77)	NC score	0.011794 (rank : 146)
Query Neighborhood Hits	108	Target Neighborhood Hits	1470	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STON2_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.015927 (rank : 137)
Query Neighborhood Hits	108	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

UBP31_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.010160 (rank : 150)
Query Neighborhood Hits	108	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

ZMYM3_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.015454 (rank : 138)
Query Neighborhood Hits	108	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

CENPT_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.020452 (rank : 134)
Query Neighborhood Hits	108	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TJM4, Q3TPY6, Q3UPD2, Q8BTH0, Q8BTP2, Q8R5E9	Gene names	Cenpt
Domain Architecture	No domain graphic available
Description	Centromere protein T (CENP-T).

MAML1_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.013446 (rank : 144)
Query Neighborhood Hits	108	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

PHF2_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.009163 (rank : 153)
Query Neighborhood Hits	108	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

SYNE2_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.003282 (rank : 157)
Query Neighborhood Hits	108	Target Neighborhood Hits	1323	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TENA_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.037669 (rank : 127)
Query Neighborhood Hits	108	Target Neighborhood Hits	631	Shared Neighborhood Hits	44
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

USH2A_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.061266 (rank : 87)
Query Neighborhood Hits	108	Target Neighborhood Hits	626	Shared Neighborhood Hits	60
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

FBN1_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.059214 (rank : 93)
Query Neighborhood Hits	108	Target Neighborhood Hits	557	Shared Neighborhood Hits	60
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.060140 (rank : 90)
Query Neighborhood Hits	108	Target Neighborhood Hits	549	Shared Neighborhood Hits	56
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

GSH2_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.001787 (rank : 159)
Query Neighborhood Hits	108	Target Neighborhood Hits	324	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZM3	Gene names	GSH2
Domain Architecture
Description	Homeobox protein GSH-2.

ITB3_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.028730 (rank : 131)
Query Neighborhood Hits	108	Target Neighborhood Hits	319	Shared Neighborhood Hits	39
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

MECP2_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.014432 (rank : 139)
Query Neighborhood Hits	108	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

CREL1_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.052698 (rank : 114)
Query Neighborhood Hits	108	Target Neighborhood Hits	524	Shared Neighborhood Hits	42
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

ERBB4_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.009802 (rank : 152)
Query Neighborhood Hits	108	Target Neighborhood Hits	910	Shared Neighborhood Hits	25
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

FBN1_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.057677 (rank : 96)
Query Neighborhood Hits	108	Target Neighborhood Hits	563	Shared Neighborhood Hits	58
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.056869 (rank : 101)
Query Neighborhood Hits	108	Target Neighborhood Hits	560	Shared Neighborhood Hits	56
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FRAS1_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.081992 (rank : 59)
Query Neighborhood Hits	108	Target Neighborhood Hits	747	Shared Neighborhood Hits	63
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

HMCN1_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.023379 (rank : 132)
Query Neighborhood Hits	108	Target Neighborhood Hits	983	Shared Neighborhood Hits	41
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

K1H2_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.003527 (rank : 156)
Query Neighborhood Hits	108	Target Neighborhood Hits	446	Shared Neighborhood Hits	5
SwissProt Accessions	Q62168	Gene names	Krtha2, Hka2, Krt1-2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

LR37A_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.011646 (rank : 147)
Query Neighborhood Hits	108	Target Neighborhood Hits	720	Shared Neighborhood Hits	12
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

POMT1_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.010441 (rank : 148)
Query Neighborhood Hits	108	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6A1, Q8NC91, Q8TCA9, Q9NX32, Q9NX82, Q9UNT2	Gene names	POMT1
Domain Architecture
Description	Protein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 1).

E2AK3_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.001470 (rank : 161)
Query Neighborhood Hits	108	Target Neighborhood Hits	859	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

LHX8_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.001628 (rank : 160)
Query Neighborhood Hits	108	Target Neighborhood Hits	406	Shared Neighborhood Hits	5
SwissProt Accessions	O35652, O70163, O88707	Gene names	Lhx8, Lhx7
Domain Architecture
Description	LIM/homeobox protein Lhx8 (LIM homeodomain Lhx7) (L3).

LRP1B_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.033640 (rank : 129)
Query Neighborhood Hits	108	Target Neighborhood Hits	606	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LTBP2_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.045088 (rank : 121)
Query Neighborhood Hits	108	Target Neighborhood Hits	552	Shared Neighborhood Hits	49
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NOTC2_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.035635 (rank : 128)
Query Neighborhood Hits	108	Target Neighborhood Hits	1069	Shared Neighborhood Hits	40
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

OSCP1_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.017437 (rank : 135)
Query Neighborhood Hits	108	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHW2, Q8BHQ7	Gene names	Oscp1
Domain Architecture	No domain graphic available
Description	Protein OSCP1.

TRI34_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.000462 (rank : 163)
Query Neighborhood Hits	108	Target Neighborhood Hits	416	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

WRN_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.004785 (rank : 155)
Query Neighborhood Hits	108	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

BMPER_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.057442 (rank : 98)
Query Neighborhood Hits	108	Target Neighborhood Hits	175	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.059628 (rank : 91)
Query Neighborhood Hits	108	Target Neighborhood Hits	194	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CREL1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.054629 (rank : 107)
Query Neighborhood Hits	108	Target Neighborhood Hits	441	Shared Neighborhood Hits	44
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.053867 (rank : 111)
Query Neighborhood Hits	108	Target Neighborhood Hits	362	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

EDAR_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.121812 (rank : 49)
Query Neighborhood Hits	108	Target Neighborhood Hits	66	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

KR104_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.052290 (rank : 116)
Query Neighborhood Hits	108	Target Neighborhood Hits	313	Shared Neighborhood Hits	39
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR107_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.053588 (rank : 112)
Query Neighborhood Hits	108	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.063412 (rank : 83)
Query Neighborhood Hits	108	Target Neighborhood Hits	288	Shared Neighborhood Hits	38
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.062962 (rank : 84)
Query Neighborhood Hits	108	Target Neighborhood Hits	236	Shared Neighborhood Hits	38
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.069193 (rank : 72)
Query Neighborhood Hits	108	Target Neighborhood Hits	331	Shared Neighborhood Hits	44
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.071205 (rank : 67)
Query Neighborhood Hits	108	Target Neighborhood Hits	270	Shared Neighborhood Hits	39
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.055747 (rank : 106)
Query Neighborhood Hits	108	Target Neighborhood Hits	257	Shared Neighborhood Hits	36
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.069114 (rank : 73)
Query Neighborhood Hits	108	Target Neighborhood Hits	207	Shared Neighborhood Hits	37
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.054048 (rank : 109)
Query Neighborhood Hits	108	Target Neighborhood Hits	269	Shared Neighborhood Hits	38
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.066912 (rank : 76)
Query Neighborhood Hits	108	Target Neighborhood Hits	324	Shared Neighborhood Hits	41
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.078961 (rank : 63)
Query Neighborhood Hits	108	Target Neighborhood Hits	310	Shared Neighborhood Hits	43
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMA1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.061371 (rank : 86)
Query Neighborhood Hits	108	Target Neighborhood Hits	804	Shared Neighborhood Hits	60
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.064619 (rank : 81)
Query Neighborhood Hits	108	Target Neighborhood Hits	838	Shared Neighborhood Hits	68
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.052449 (rank : 115)
Query Neighborhood Hits	108	Target Neighborhood Hits	1198	Shared Neighborhood Hits	58
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.052123 (rank : 117)
Query Neighborhood Hits	108	Target Neighborhood Hits	760	Shared Neighborhood Hits	53
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA3_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.062222 (rank : 85)
Query Neighborhood Hits	108	Target Neighborhood Hits	859	Shared Neighborhood Hits	67
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA5_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.078973 (rank : 62)
Query Neighborhood Hits	108	Target Neighborhood Hits	976	Shared Neighborhood Hits	67
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.057544 (rank : 97)
Query Neighborhood Hits	108	Target Neighborhood Hits	1018	Shared Neighborhood Hits	58
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.061092 (rank : 88)
Query Neighborhood Hits	108	Target Neighborhood Hits	919	Shared Neighborhood Hits	63
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.069918 (rank : 69)
Query Neighborhood Hits	108	Target Neighborhood Hits	922	Shared Neighborhood Hits	63
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.065798 (rank : 77)
Query Neighborhood Hits	108	Target Neighborhood Hits	856	Shared Neighborhood Hits	61
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.078747 (rank : 64)
Query Neighborhood Hits	108	Target Neighborhood Hits	588	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.085149 (rank : 56)
Query Neighborhood Hits	108	Target Neighborhood Hits	624	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEGF8_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.056287 (rank : 102)
Query Neighborhood Hits	108	Target Neighborhood Hits	528	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.069916 (rank : 70)
Query Neighborhood Hits	108	Target Neighborhood Hits	557	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.065682 (rank : 78)
Query Neighborhood Hits	108	Target Neighborhood Hits	896	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MT3_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.054031 (rank : 110)
Query Neighborhood Hits	108	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MUC2_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.059184 (rank : 94)
Query Neighborhood Hits	108	Target Neighborhood Hits	906	Shared Neighborhood Hits	43
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PCSK5_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.069615 (rank : 71)
Query Neighborhood Hits	108	Target Neighborhood Hits	291	Shared Neighborhood Hits	57
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK6_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.070125 (rank : 68)
Query Neighborhood Hits	108	Target Neighborhood Hits	298	Shared Neighborhood Hits	59
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

RSPO1_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.054249 (rank : 108)
Query Neighborhood Hits	108	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

SREC2_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.059522 (rank : 92)
Query Neighborhood Hits	108	Target Neighborhood Hits	645	Shared Neighborhood Hits	52
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.056952 (rank : 100)
Query Neighborhood Hits	108	Target Neighborhood Hits	605	Shared Neighborhood Hits	51
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.068221 (rank : 75)
Query Neighborhood Hits	108	Target Neighborhood Hits	645	Shared Neighborhood Hits	57
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.059076 (rank : 95)
Query Neighborhood Hits	108	Target Neighborhood Hits	566	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.053124 (rank : 113)
Query Neighborhood Hits	108	Target Neighborhood Hits	534	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.055761 (rank : 105)
Query Neighborhood Hits	108	Target Neighborhood Hits	528	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TECTA_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.055969 (rank : 103)
Query Neighborhood Hits	108	Target Neighborhood Hits	239	Shared Neighborhood Hits	30
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.057144 (rank : 99)
Query Neighborhood Hits	108	Target Neighborhood Hits	244	Shared Neighborhood Hits	29
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TNR19_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.160149 (rank : 45)
Query Neighborhood Hits	108	Target Neighborhood Hits	89	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.196801 (rank : 42)
Query Neighborhood Hits	108	Target Neighborhood Hits	100	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR27_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.183062 (rank : 44)
Query Neighborhood Hits	108	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR6_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.390331 (rank : 35)
Query Neighborhood Hits	108	Target Neighborhood Hits	95	Shared Neighborhood Hits	40
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.415340 (rank : 32)
Query Neighborhood Hits	108	Target Neighborhood Hits	99	Shared Neighborhood Hits	41
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.370208 (rank : 36)
Query Neighborhood Hits	108	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR7_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.343210 (rank : 38)
Query Neighborhood Hits	108	Target Neighborhood Hits	112	Shared Neighborhood Hits	42
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TR10B_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.321634 (rank : 39)
Query Neighborhood Hits	108	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR19L_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.193757 (rank : 43)
Query Neighborhood Hits	108	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.206123 (rank : 41)
Query Neighborhood Hits	108	Target Neighborhood Hits	85	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

USH2A_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.055924 (rank : 104)
Query Neighborhood Hits	108	Target Neighborhood Hits	600	Shared Neighborhood Hits	60
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

Hits sorted by NC score

TNR21_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	108	Target Neighborhood Hits	108	Shared Neighborhood Hits	108
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_HUMAN
NC score	0.985158 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	108	Target Neighborhood Hits	90	Shared Neighborhood Hits	65
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR6B_HUMAN
NC score	0.796757 (rank : 3)	θ value	1.24688e-25 (rank : 4)
Query Neighborhood Hits	108	Target Neighborhood Hits	103	Shared Neighborhood Hits	51
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TR11B_HUMAN
NC score	0.790015 (rank : 4)	θ value	3.28125e-26 (rank : 3)
Query Neighborhood Hits	108	Target Neighborhood Hits	92	Shared Neighborhood Hits	46
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR1B_HUMAN
NC score	0.784331 (rank : 5)	θ value	8.08199e-25 (rank : 6)
Query Neighborhood Hits	108	Target Neighborhood Hits	127	Shared Neighborhood Hits	42
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1B_MOUSE
NC score	0.782962 (rank : 6)	θ value	3.39556e-23 (rank : 7)
Query Neighborhood Hits	108	Target Neighborhood Hits	123	Shared Neighborhood Hits	51
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TR11B_MOUSE
NC score	0.779565 (rank : 7)	θ value	3.62785e-25 (rank : 5)
Query Neighborhood Hits	108	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR3_HUMAN
NC score	0.726936 (rank : 8)	θ value	8.10077e-17 (rank : 9)
Query Neighborhood Hits	108	Target Neighborhood Hits	145	Shared Neighborhood Hits	51
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR5_MOUSE
NC score	0.726030 (rank : 9)	θ value	8.65492e-19 (rank : 8)
Query Neighborhood Hits	108	Target Neighborhood Hits	131	Shared Neighborhood Hits	47
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR3_MOUSE
NC score	0.721152 (rank : 10)	θ value	3.40345e-15 (rank : 10)
Query Neighborhood Hits	108	Target Neighborhood Hits	113	Shared Neighborhood Hits	55
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR14_HUMAN
NC score	0.712452 (rank : 11)	θ value	1.42992e-13 (rank : 13)
Query Neighborhood Hits	108	Target Neighborhood Hits	149	Shared Neighborhood Hits	61
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR5_HUMAN
NC score	0.704663 (rank : 12)	θ value	6.00763e-12 (rank : 15)
Query Neighborhood Hits	108	Target Neighborhood Hits	102	Shared Neighborhood Hits	46
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR9_HUMAN
NC score	0.682843 (rank : 13)	θ value	4.44505e-15 (rank : 11)
Query Neighborhood Hits	108	Target Neighborhood Hits	166	Shared Neighborhood Hits	59
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR11_HUMAN
NC score	0.679143 (rank : 14)	θ value	1.09485e-13 (rank : 12)
Query Neighborhood Hits	108	Target Neighborhood Hits	135	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
NC score	0.677876 (rank : 15)	θ value	3.52202e-12 (rank : 14)
Query Neighborhood Hits	108	Target Neighborhood Hits	121	Shared Neighborhood Hits	49
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR9_MOUSE
NC score	0.650133 (rank : 16)	θ value	2.13673e-09 (rank : 19)
Query Neighborhood Hits	108	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR26_MOUSE
NC score	0.640093 (rank : 17)	θ value	8.97725e-08 (rank : 22)
Query Neighborhood Hits	108	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR23_MOUSE
NC score	0.638717 (rank : 18)	θ value	7.84624e-12 (rank : 16)
Query Neighborhood Hits	108	Target Neighborhood Hits	114	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR22_MOUSE
NC score	0.632448 (rank : 19)	θ value	3.08544e-08 (rank : 21)
Query Neighborhood Hits	108	Target Neighborhood Hits	97	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR16_MOUSE
NC score	0.610707 (rank : 20)	θ value	2.52405e-10 (rank : 18)
Query Neighborhood Hits	108	Target Neighborhood Hits	178	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR16_HUMAN
NC score	0.598609 (rank : 21)	θ value	2.52405e-10 (rank : 17)
Query Neighborhood Hits	108	Target Neighborhood Hits	183	Shared Neighborhood Hits	61
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR8_HUMAN
NC score	0.593513 (rank : 22)	θ value	8.11959e-09 (rank : 20)
Query Neighborhood Hits	108	Target Neighborhood Hits	198	Shared Neighborhood Hits	53
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR4_HUMAN
NC score	0.592399 (rank : 23)	θ value	2.21117e-06 (rank : 25)
Query Neighborhood Hits	108	Target Neighborhood Hits	152	Shared Neighborhood Hits	51
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR4_MOUSE
NC score	0.545197 (rank : 24)	θ value	0.0113563 (rank : 33)
Query Neighborhood Hits	108	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR1A_MOUSE
NC score	0.542818 (rank : 25)	θ value	9.92553e-07 (rank : 24)
Query Neighborhood Hits	108	Target Neighborhood Hits	131	Shared Neighborhood Hits	46
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR1A_HUMAN
NC score	0.517615 (rank : 26)	θ value	4.1701e-05 (rank : 27)
Query Neighborhood Hits	108	Target Neighborhood Hits	121	Shared Neighborhood Hits	45
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR8_MOUSE
NC score	0.514868 (rank : 27)	θ value	3.41135e-07 (rank : 23)
Query Neighborhood Hits	108	Target Neighborhood Hits	208	Shared Neighborhood Hits	50
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR18_HUMAN
NC score	0.487901 (rank : 28)	θ value	5.44631e-05 (rank : 28)
Query Neighborhood Hits	108	Target Neighborhood Hits	55	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR25_HUMAN
NC score	0.469777 (rank : 29)	θ value	7.1131e-05 (rank : 29)
Query Neighborhood Hits	108	Target Neighborhood Hits	172	Shared Neighborhood Hits	61
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TR10C_HUMAN
NC score	0.456082 (rank : 30)	θ value	8.40245e-06 (rank : 26)
Query Neighborhood Hits	108	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR10B_HUMAN
NC score	0.427244 (rank : 31)	θ value	0.00020696 (rank : 31)
Query Neighborhood Hits	108	Target Neighborhood Hits	71	Shared Neighborhood Hits	40
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TNR6_MOUSE
NC score	0.415340 (rank : 32)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	108	Target Neighborhood Hits	99	Shared Neighborhood Hits	41
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TR10A_HUMAN
NC score	0.413163 (rank : 33)	θ value	0.000158464 (rank : 30)
Query Neighborhood Hits	108	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10D_HUMAN
NC score	0.392746 (rank : 34)	θ value	0.0252991 (rank : 36)
Query Neighborhood Hits	108	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TNR6_HUMAN
NC score	0.390331 (rank : 35)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	108	Target Neighborhood Hits	95	Shared Neighborhood Hits	40
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
NC score	0.370208 (rank : 36)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	108	Target Neighborhood Hits	120	Shared Neighborhood Hits	46
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR18_MOUSE
NC score	0.354207 (rank : 37)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	108	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR7_MOUSE
NC score	0.343210 (rank : 38)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	108	Target Neighborhood Hits	112	Shared Neighborhood Hits	42
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TR10B_MOUSE
NC score	0.321634 (rank : 39)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	108	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR27_HUMAN
NC score	0.243549 (rank : 40)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	108	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TR19L_MOUSE
NC score	0.206123 (rank : 41)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	108	Target Neighborhood Hits	85	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TNR19_MOUSE
NC score	0.196801 (rank : 42)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	108	Target Neighborhood Hits	100	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TR19L_HUMAN
NC score	0.193757 (rank : 43)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	108	Target Neighborhood Hits	99	Shared Neighborhood Hits	35
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TNR27_MOUSE
NC score	0.183062 (rank : 44)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	108	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR19_HUMAN
NC score	0.160149 (rank : 45)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	108	Target Neighborhood Hits	89	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

EDAR_HUMAN
NC score	0.147417 (rank : 46)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	108	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

ZAN_MOUSE
NC score	0.126604 (rank : 47)	θ value	0.0148317 (rank : 34)
Query Neighborhood Hits	108	Target Neighborhood Hits	808	Shared Neighborhood Hits	66
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

PCSK5_MOUSE
NC score	0.122298 (rank : 48)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	108	Target Neighborhood Hits	613	Shared Neighborhood Hits	75
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

EDAR_MOUSE
NC score	0.121812 (rank : 49)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	108	Target Neighborhood Hits	66	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

FRAS1_HUMAN
NC score	0.096287 (rank : 50)	θ value	0.125558 (rank : 42)
Query Neighborhood Hits	108	Target Neighborhood Hits	759	Shared Neighborhood Hits	63
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SCUB3_MOUSE
NC score	0.091339 (rank : 51)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	108	Target Neighborhood Hits	442	Shared Neighborhood Hits	67
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SSPO_MOUSE
NC score	0.090160 (rank : 52)	θ value	0.00298849 (rank : 32)
Query Neighborhood Hits	108	Target Neighborhood Hits	800	Shared Neighborhood Hits	57
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

SCUB3_HUMAN
NC score	0.089744 (rank : 53)	θ value	0.0961366 (rank : 40)
Query Neighborhood Hits	108	Target Neighborhood Hits	428	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

ZAN_HUMAN
NC score	0.089393 (rank : 54)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	108	Target Neighborhood Hits	679	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

LAMC2_MOUSE
NC score	0.087589 (rank : 55)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	108	Target Neighborhood Hits	614	Shared Neighborhood Hits	67
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_MOUSE
NC score	0.085149 (rank : 56)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	108	Target Neighborhood Hits	624	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_MOUSE
NC score	0.084296 (rank : 57)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	108	Target Neighborhood Hits	828	Shared Neighborhood Hits	69
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

VWF_MOUSE
NC score	0.083119 (rank : 58)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	108	Target Neighborhood Hits	381	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FRAS1_MOUSE
NC score	0.081992 (rank : 59)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	108	Target Neighborhood Hits	747	Shared Neighborhood Hits	63
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

VWF_HUMAN
NC score	0.080453 (rank : 60)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	108	Target Neighborhood Hits	396	Shared Neighborhood Hits	43
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MUC5B_HUMAN
NC score	0.080246 (rank : 61)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	108	Target Neighborhood Hits	1020	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

LAMA5_HUMAN
NC score	0.078973 (rank : 62)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	108	Target Neighborhood Hits	976	Shared Neighborhood Hits	67
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

KRA59_HUMAN
NC score	0.078961 (rank : 63)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	108	Target Neighborhood Hits	310	Shared Neighborhood Hits	43
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMC3_HUMAN
NC score	0.078747 (rank : 64)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	108	Target Neighborhood Hits	588	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC2_HUMAN
NC score	0.073346 (rank : 65)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	108	Target Neighborhood Hits	715	Shared Neighborhood Hits	60
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

MEGF6_HUMAN
NC score	0.072696 (rank : 66)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	108	Target Neighborhood Hits	671	Shared Neighborhood Hits	64
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KRA54_HUMAN
NC score	0.071205 (rank : 67)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	108	Target Neighborhood Hits	270	Shared Neighborhood Hits	39
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

PCSK6_HUMAN
NC score	0.070125 (rank : 68)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	108	Target Neighborhood Hits	298	Shared Neighborhood Hits	59
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

LAMC1_HUMAN
NC score	0.069918 (rank : 69)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	108	Target Neighborhood Hits	922	Shared Neighborhood Hits	63
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

MEGF9_HUMAN
NC score	0.069916 (rank : 70)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	108	Target Neighborhood Hits	557	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PCSK5_HUMAN
NC score	0.069615 (rank : 71)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	108	Target Neighborhood Hits	291	Shared Neighborhood Hits	57
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

KRA53_HUMAN
NC score	0.069193 (rank : 72)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	108	Target Neighborhood Hits	331	Shared Neighborhood Hits	44
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA56_HUMAN
NC score	0.069114 (rank : 73)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	108	Target Neighborhood Hits	207	Shared Neighborhood Hits	37
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LAMB2_MOUSE
NC score	0.069110 (rank : 74)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	108	Target Neighborhood Hits	722	Shared Neighborhood Hits	58
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

SREC_HUMAN
NC score	0.068221 (rank : 75)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	108	Target Neighborhood Hits	645	Shared Neighborhood Hits	57
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

KRA58_HUMAN
NC score	0.066912 (rank : 76)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	108	Target Neighborhood Hits	324	Shared Neighborhood Hits	41
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMC1_MOUSE
NC score	0.065798 (rank : 77)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	108	Target Neighborhood Hits	856	Shared Neighborhood Hits	61
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

MEGF9_MOUSE
NC score	0.065682 (rank : 78)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	108	Target Neighborhood Hits	896	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMB2_HUMAN
NC score	0.065446 (rank : 79)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	108	Target Neighborhood Hits	692	Shared Neighborhood Hits	54
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

STAB1_HUMAN
NC score	0.065292 (rank : 80)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	108	Target Neighborhood Hits	546	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

LAMA1_MOUSE
NC score	0.064619 (rank : 81)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	108	Target Neighborhood Hits	838	Shared Neighborhood Hits	68
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
NC score	0.063768 (rank : 82)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	108	Target Neighborhood Hits	1092	Shared Neighborhood Hits	63
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KRA51_HUMAN
NC score	0.063412 (rank : 83)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	108	Target Neighborhood Hits	288	Shared Neighborhood Hits	38
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
NC score	0.062962 (rank : 84)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	108	Target Neighborhood Hits	236	Shared Neighborhood Hits	38
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LAMA3_MOUSE
NC score	0.062222 (rank : 85)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	108	Target Neighborhood Hits	859	Shared Neighborhood Hits	67
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA1_HUMAN
NC score	0.061371 (rank : 86)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	108	Target Neighborhood Hits	804	Shared Neighborhood Hits	60
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

USH2A_MOUSE
NC score	0.061266 (rank : 87)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	108	Target Neighborhood Hits	626	Shared Neighborhood Hits	60
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LAMB1_MOUSE
NC score	0.061092 (rank : 88)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	108	Target Neighborhood Hits	919	Shared Neighborhood Hits	63
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

FBN3_HUMAN
NC score	0.060980 (rank : 89)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	108	Target Neighborhood Hits	543	Shared Neighborhood Hits	58
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN2_MOUSE
NC score	0.060140 (rank : 90)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	108	Target Neighborhood Hits	549	Shared Neighborhood Hits	56
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

BMPER_MOUSE
NC score	0.059628 (rank : 91)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	108	Target Neighborhood Hits	194	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

SREC2_HUMAN
NC score	0.059522 (rank : 92)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	108	Target Neighborhood Hits	645	Shared Neighborhood Hits	52
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

FBN1_HUMAN
NC score	0.059214 (rank : 93)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	108	Target Neighborhood Hits	557	Shared Neighborhood Hits	60
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

MUC2_HUMAN
NC score	0.059184 (rank : 94)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	108	Target Neighborhood Hits	906	Shared Neighborhood Hits	43
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

STAB1_MOUSE
NC score	0.059076 (rank : 95)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	108	Target Neighborhood Hits	566	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

FBN1_MOUSE
NC score	0.057677 (rank : 96)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	108	Target Neighborhood Hits	563	Shared Neighborhood Hits	58
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LAMB1_HUMAN
NC score	0.057544 (rank : 97)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	108	Target Neighborhood Hits	1018	Shared Neighborhood Hits	58
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

BMPER_HUMAN
NC score	0.057442 (rank : 98)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	108	Target Neighborhood Hits	175	Shared Neighborhood Hits	29
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

TECTA_MOUSE
NC score	0.057144 (rank : 99)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	108	Target Neighborhood Hits	244	Shared Neighborhood Hits	29
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

SREC2_MOUSE
NC score	0.056952 (rank : 100)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	108	Target Neighborhood Hits	605	Shared Neighborhood Hits	51
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

FBN2_HUMAN
NC score	0.056869 (rank : 101)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	108	Target Neighborhood Hits	560	Shared Neighborhood Hits	56
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

MEGF8_HUMAN
NC score	0.056287 (rank : 102)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	108	Target Neighborhood Hits	528	Shared Neighborhood Hits	51
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TECTA_HUMAN
NC score	0.055969 (rank : 103)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	108	Target Neighborhood Hits	239	Shared Neighborhood Hits	30
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

USH2A_HUMAN
NC score	0.055924 (rank : 104)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	108	Target Neighborhood Hits	600	Shared Neighborhood Hits	60
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

STAB2_MOUSE
NC score	0.055761 (rank : 105)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	108	Target Neighborhood Hits	528	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

KRA55_HUMAN
NC score	0.055747 (rank : 106)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	108	Target Neighborhood Hits	257	Shared Neighborhood Hits	36
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

CREL1_HUMAN
NC score	0.054629 (rank : 107)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	108	Target Neighborhood Hits	441	Shared Neighborhood Hits	44
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

RSPO1_HUMAN
NC score	0.054249 (rank : 108)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	108	Target Neighborhood Hits	101	Shared Neighborhood Hits	21
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

KRA57_HUMAN
NC score	0.054048 (rank : 109)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	108	Target Neighborhood Hits	269	Shared Neighborhood Hits	38
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

MT3_MOUSE
NC score	0.054031 (rank : 110)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	108	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

CRIM1_HUMAN
NC score	0.053867 (rank : 111)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	108	Target Neighborhood Hits	362	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KR107_HUMAN
NC score	0.053588 (rank : 112)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	108	Target Neighborhood Hits	330	Shared Neighborhood Hits	41
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

STAB2_HUMAN
NC score	0.053124 (rank : 113)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	108	Target Neighborhood Hits	534	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

CREL1_MOUSE
NC score	0.052698 (rank : 114)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	108	Target Neighborhood Hits	524	Shared Neighborhood Hits	42
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LAMA2_MOUSE
NC score	0.052449 (rank : 115)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	108	Target Neighborhood Hits	1198	Shared Neighborhood Hits	58
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KR104_HUMAN
NC score	0.052290 (rank : 116)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	108	Target Neighborhood Hits	313	Shared Neighborhood Hits	39
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LAMA3_HUMAN
NC score	0.052123 (rank : 117)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	108	Target Neighborhood Hits	760	Shared Neighborhood Hits	53
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

WIF1_MOUSE
NC score	0.050154 (rank : 118)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	108	Target Neighborhood Hits	393	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_HUMAN
NC score	0.049914 (rank : 119)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	108	Target Neighborhood Hits	392	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ADA17_HUMAN
NC score	0.049848 (rank : 120)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	108	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

LTBP2_HUMAN
NC score	0.045088 (rank : 121)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	108	Target Neighborhood Hits	552	Shared Neighborhood Hits	49
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TENX_HUMAN
NC score	0.043499 (rank : 122)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	108	Target Neighborhood Hits	789	Shared Neighborhood Hits	50
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ADA17_MOUSE
NC score	0.043364 (rank : 123)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	108	Target Neighborhood Hits	201	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

THYG_MOUSE
NC score	0.042559 (rank : 124)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	108	Target Neighborhood Hits	161	Shared Neighborhood Hits	31
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TSP4_HUMAN
NC score	0.040071 (rank : 125)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	108	Target Neighborhood Hits	277	Shared Neighborhood Hits	33
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

PODXL_HUMAN
NC score	0.039830 (rank : 126)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	108	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

TENA_HUMAN
NC score	0.037669 (rank : 127)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	108	Target Neighborhood Hits	631	Shared Neighborhood Hits	44
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

NOTC2_MOUSE
NC score	0.035635 (rank : 128)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	108	Target Neighborhood Hits	1069	Shared Neighborhood Hits	40
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LRP1B_MOUSE
NC score	0.033640 (rank : 129)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	108	Target Neighborhood Hits	606	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

PALM_MOUSE
NC score	0.029853 (rank : 130)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	108	Target Neighborhood Hits	228	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

ITB3_MOUSE
NC score	0.028730 (rank : 131)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	108	Target Neighborhood Hits	319	Shared Neighborhood Hits	39
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

HMCN1_HUMAN
NC score	0.023379 (rank : 132)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	108	Target Neighborhood Hits	983	Shared Neighborhood Hits	41
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HCFC1_MOUSE
NC score	0.021173 (rank : 133)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	108	Target Neighborhood Hits	348	Shared Neighborhood Hits	11
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

CENPT_MOUSE
NC score	0.020452 (rank : 134)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	108	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TJM4, Q3TPY6, Q3UPD2, Q8BTH0, Q8BTP2, Q8R5E9	Gene names	Cenpt
Domain Architecture	No domain graphic available
Description	Centromere protein T (CENP-T).

OSCP1_MOUSE
NC score	0.017437 (rank : 135)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	108	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHW2, Q8BHQ7	Gene names	Oscp1
Domain Architecture	No domain graphic available
Description	Protein OSCP1.

EPHA7_HUMAN
NC score	0.016434 (rank : 136)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	108	Target Neighborhood Hits	1053	Shared Neighborhood Hits	41
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

STON2_HUMAN
NC score	0.015927 (rank : 137)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	108	Target Neighborhood Hits	115	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

ZMYM3_MOUSE
NC score	0.015454 (rank : 138)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	108	Target Neighborhood Hits	177	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLM4, Q80U17	Gene names	Zmym3, Kiaa0385, Zfp261, Znf261
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 3 (Zinc finger protein 261) (DXHXS6673E protein).

MECP2_MOUSE
NC score	0.014432 (rank : 139)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	108	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2D6	Gene names	Mecp2
Domain Architecture
Description	Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2).

EGFR_HUMAN
NC score	0.014407 (rank : 140)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	108	Target Neighborhood Hits	939	Shared Neighborhood Hits	31
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EPHB2_HUMAN
NC score	0.014298 (rank : 141)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	108	Target Neighborhood Hits	983	Shared Neighborhood Hits	32
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHA7_MOUSE
NC score	0.014295 (rank : 142)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	108	Target Neighborhood Hits	1025	Shared Neighborhood Hits	40
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHB2_MOUSE
NC score	0.014264 (rank : 143)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	108	Target Neighborhood Hits	982	Shared Neighborhood Hits	32
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

MAML1_HUMAN
NC score	0.013446 (rank : 144)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	108	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

KIF5C_HUMAN
NC score	0.011835 (rank : 145)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	108	Target Neighborhood Hits	974	Shared Neighborhood Hits	10
SwissProt Accessions	O60282, O95079	Gene names	KIF5C, KIAA0531, NKHC2
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

SRRM2_MOUSE
NC score	0.011794 (rank : 146)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	108	Target Neighborhood Hits	1470	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

LR37A_HUMAN
NC score	0.011646 (rank : 147)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	108	Target Neighborhood Hits	720	Shared Neighborhood Hits	12
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

POMT1_HUMAN
NC score	0.010441 (rank : 148)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	108	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6A1, Q8NC91, Q8TCA9, Q9NX32, Q9NX82, Q9UNT2	Gene names	POMT1
Domain Architecture
Description	Protein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 1).

FOXE2_HUMAN
NC score	0.010409 (rank : 149)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	108	Target Neighborhood Hits	236	Shared Neighborhood Hits	5
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

UBP31_HUMAN
NC score	0.010160 (rank : 150)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	108	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

KIF5C_MOUSE
NC score	0.009902 (rank : 151)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	108	Target Neighborhood Hits	1040	Shared Neighborhood Hits	12
SwissProt Accessions	P28738, Q9Z2F8	Gene names	Kif5c, Nkhc2
Domain Architecture
Description	Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2).

ERBB4_HUMAN
NC score	0.009802 (rank : 152)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	108	Target Neighborhood Hits	910	Shared Neighborhood Hits	25
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

PHF2_MOUSE
NC score	0.009163 (rank : 153)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	108	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

M3K12_MOUSE
NC score	0.006350 (rank : 154)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	108	Target Neighborhood Hits	957	Shared Neighborhood Hits	9
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

WRN_MOUSE
NC score	0.004785 (rank : 155)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	108	Target Neighborhood Hits	295	Shared Neighborhood Hits	3
SwissProt Accessions	O09053, O09050, Q9JKD4, Q9Z241, Q9Z242	Gene names	Wrn
Domain Architecture
Description	Werner syndrome ATP-dependent helicase homolog (EC 3.6.1.-).

K1H2_MOUSE
NC score	0.003527 (rank : 156)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	108	Target Neighborhood Hits	446	Shared Neighborhood Hits	5
SwissProt Accessions	Q62168	Gene names	Krtha2, Hka2, Krt1-2
Domain Architecture
Description	Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2).

SYNE2_HUMAN
NC score	0.003282 (rank : 157)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	108	Target Neighborhood Hits	1323	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

PCDGI_HUMAN
NC score	0.002346 (rank : 158)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	108	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5F9, Q9Y5C5	Gene names	PCDHGB6
Domain Architecture
Description	Protocadherin gamma B6 precursor (PCDH-gamma-B6).

GSH2_HUMAN
NC score	0.001787 (rank : 159)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	108	Target Neighborhood Hits	324	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZM3	Gene names	GSH2
Domain Architecture
Description	Homeobox protein GSH-2.

LHX8_MOUSE
NC score	0.001628 (rank : 160)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	108	Target Neighborhood Hits	406	Shared Neighborhood Hits	5
SwissProt Accessions	O35652, O70163, O88707	Gene names	Lhx8, Lhx7
Domain Architecture
Description	LIM/homeobox protein Lhx8 (LIM homeodomain Lhx7) (L3).

E2AK3_HUMAN
NC score	0.001470 (rank : 161)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	108	Target Neighborhood Hits	859	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZJ5, O95846	Gene names	EIF2AK3, PEK, PERK
Domain Architecture
Description	Eukaryotic translation initiation factor 2-alpha kinase 3 precursor (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase) (HsPEK).

DRD2_HUMAN
NC score	0.001399 (rank : 162)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	108	Target Neighborhood Hits	774	Shared Neighborhood Hits	3
SwissProt Accessions	P14416, Q9NZR3, Q9UPA9	Gene names	DRD2
Domain Architecture
Description	D(2) dopamine receptor (Dopamine D2 receptor).

TRI34_HUMAN
NC score	0.000462 (rank : 163)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	108	Target Neighborhood Hits	416	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).