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Network neighborhood for query Sequence : TNR18_MOUSE

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TNR18_MOUSE
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TNR18_MOUSE
θ value	4.28312e-143 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR18_HUMAN
θ value	1.18825e-76 (rank : 2)	NC score	0.944984 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR9_HUMAN
θ value	1.52774e-15 (rank : 3)	NC score	0.601700 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	166	Shared Neighborhood Hits	26
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR9_MOUSE
θ value	2.0648e-12 (rank : 4)	NC score	0.589602 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	137	Shared Neighborhood Hits	26
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR4_MOUSE
θ value	1.29631e-06 (rank : 5)	NC score	0.441702 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TR11B_HUMAN
θ value	9.29e-05 (rank : 6)	NC score	0.425661 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	92	Shared Neighborhood Hits	23
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR11B_MOUSE
θ value	0.000158464 (rank : 7)	NC score	0.423207 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	95	Shared Neighborhood Hits	23
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR11_MOUSE
θ value	0.000461057 (rank : 8)	NC score	0.420347 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	121	Shared Neighborhood Hits	23
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR4_HUMAN
θ value	0.00102713 (rank : 9)	NC score	0.438379 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	152	Shared Neighborhood Hits	25
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR6B_HUMAN
θ value	0.00134147 (rank : 10)	NC score	0.429943 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	103	Shared Neighborhood Hits	24
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR5_MOUSE
θ value	0.00228821 (rank : 11)	NC score	0.415695 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	131	Shared Neighborhood Hits	25
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR3_HUMAN
θ value	0.00298849 (rank : 12)	NC score	0.391158 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	145	Shared Neighborhood Hits	21
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR11_HUMAN
θ value	0.00390308 (rank : 13)	NC score	0.415086 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	135	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR3_MOUSE
θ value	0.00509761 (rank : 14)	NC score	0.398408 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR5_HUMAN
θ value	0.00509761 (rank : 15)	NC score	0.418884 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	102	Shared Neighborhood Hits	25
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR1B_MOUSE
θ value	0.0252991 (rank : 16)	NC score	0.387810 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR21_HUMAN
θ value	0.0431538 (rank : 17)	NC score	0.376977 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	90	Shared Neighborhood Hits	23
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR1B_HUMAN
θ value	0.0961366 (rank : 18)	NC score	0.375368 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	127	Shared Neighborhood Hits	23
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR21_MOUSE
θ value	0.365318 (rank : 19)	NC score	0.354207 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	108	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR14_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.336652 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	149	Shared Neighborhood Hits	29
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TS1R2_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.022053 (rank : 58)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

EDAR_MOUSE
θ value	1.06291 (rank : 22)	NC score	0.146203 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	66	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

TSP4_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.026271 (rank : 55)
Query Neighborhood Hits	36	Target Neighborhood Hits	276	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

KRA93_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.033883 (rank : 49)
Query Neighborhood Hits	36	Target Neighborhood Hits	203	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

NOTC1_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.015305 (rank : 60)
Query Neighborhood Hits	36	Target Neighborhood Hits	906	Shared Neighborhood Hits	14
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

STAB2_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.028576 (rank : 51)
Query Neighborhood Hits	36	Target Neighborhood Hits	528	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

EDAR_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.120125 (rank : 39)
Query Neighborhood Hits	36	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

GRN_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.026577 (rank : 53)
Query Neighborhood Hits	36	Target Neighborhood Hits	268	Shared Neighborhood Hits	12
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

STAB2_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.029559 (rank : 50)
Query Neighborhood Hits	36	Target Neighborhood Hits	534	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

CRIM1_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.026837 (rank : 52)
Query Neighborhood Hits	36	Target Neighborhood Hits	362	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

FBN1_HUMAN
θ value	6.88961 (rank : 31)	NC score	0.022422 (rank : 57)
Query Neighborhood Hits	36	Target Neighborhood Hits	557	Shared Neighborhood Hits	22
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

KRA98_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.026403 (rank : 54)
Query Neighborhood Hits	36	Target Neighborhood Hits	185	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

PGBM_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.020529 (rank : 59)
Query Neighborhood Hits	36	Target Neighborhood Hits	1073	Shared Neighborhood Hits	26
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TSP4_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.022962 (rank : 56)
Query Neighborhood Hits	36	Target Neighborhood Hits	277	Shared Neighborhood Hits	9
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

ZDH15_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.012069 (rank : 62)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MV8, Q3SY30, Q6UWH3	Gene names	ZDHHC15
Domain Architecture
Description	Palmitoyltransferase ZDHHC15 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 15) (DHHC-15).

ZDH15_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.012112 (rank : 61)
Query Neighborhood Hits	36	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGJ0, Q3TV63, Q8BMB7	Gene names	Zdhhc15
Domain Architecture	No domain graphic available
Description	Palmitoyltransferase ZDHHC15 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 15) (DHHC-15).

MT3_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.069546 (rank : 48)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

TNR16_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.201082 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	183	Shared Neighborhood Hits	23
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.205444 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	178	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR19_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.080795 (rank : 47)
Query Neighborhood Hits	36	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.120331 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	100	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1A_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.149587 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	121	Shared Neighborhood Hits	18
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR1A_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.165519 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	131	Shared Neighborhood Hits	17
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR22_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.199355 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.214525 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR25_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.145582 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	172	Shared Neighborhood Hits	21
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR26_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.210163 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	106	Shared Neighborhood Hits	22
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR27_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.114118 (rank : 40)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR27_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.092284 (rank : 46)
Query Neighborhood Hits	36	Target Neighborhood Hits	61	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR6_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.169863 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	95	Shared Neighborhood Hits	19
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.182922 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.203737 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR7_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.193143 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	112	Shared Neighborhood Hits	19
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR8_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.180272 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.164863 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	208	Shared Neighborhood Hits	25
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TR10A_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.110091 (rank : 42)
Query Neighborhood Hits	36	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.108244 (rank : 43)
Query Neighborhood Hits	36	Target Neighborhood Hits	71	Shared Neighborhood Hits	17
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10B_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.095167 (rank : 45)
Query Neighborhood Hits	36	Target Neighborhood Hits	76	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR10C_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.123617 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR10D_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.105926 (rank : 44)
Query Neighborhood Hits	36	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR19L_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.136828 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.110443 (rank : 41)
Query Neighborhood Hits	36	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

Hits sorted by NC score

TNR18_MOUSE
NC score	0.999962 (rank : 1)	θ value	4.28312e-143 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR18_HUMAN
NC score	0.944984 (rank : 2)	θ value	1.18825e-76 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR9_HUMAN
NC score	0.601700 (rank : 3)	θ value	1.52774e-15 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	166	Shared Neighborhood Hits	26
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR9_MOUSE
NC score	0.589602 (rank : 4)	θ value	2.0648e-12 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	137	Shared Neighborhood Hits	26
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR4_MOUSE
NC score	0.441702 (rank : 5)	θ value	1.29631e-06 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR4_HUMAN
NC score	0.438379 (rank : 6)	θ value	0.00102713 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	152	Shared Neighborhood Hits	25
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR6B_HUMAN
NC score	0.429943 (rank : 7)	θ value	0.00134147 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	103	Shared Neighborhood Hits	24
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TR11B_HUMAN
NC score	0.425661 (rank : 8)	θ value	9.29e-05 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	92	Shared Neighborhood Hits	23
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR11B_MOUSE
NC score	0.423207 (rank : 9)	θ value	0.000158464 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	95	Shared Neighborhood Hits	23
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR11_MOUSE
NC score	0.420347 (rank : 10)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	121	Shared Neighborhood Hits	23
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR5_HUMAN
NC score	0.418884 (rank : 11)	θ value	0.00509761 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	102	Shared Neighborhood Hits	25
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR5_MOUSE
NC score	0.415695 (rank : 12)	θ value	0.00228821 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	131	Shared Neighborhood Hits	25
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR11_HUMAN
NC score	0.415086 (rank : 13)	θ value	0.00390308 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	135	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR3_MOUSE
NC score	0.398408 (rank : 14)	θ value	0.00509761 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	113	Shared Neighborhood Hits	24
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR3_HUMAN
NC score	0.391158 (rank : 15)	θ value	0.00298849 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	145	Shared Neighborhood Hits	21
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR1B_MOUSE
NC score	0.387810 (rank : 16)	θ value	0.0252991 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	123	Shared Neighborhood Hits	25
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR21_HUMAN
NC score	0.376977 (rank : 17)	θ value	0.0431538 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	90	Shared Neighborhood Hits	23
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR1B_HUMAN
NC score	0.375368 (rank : 18)	θ value	0.0961366 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	127	Shared Neighborhood Hits	23
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR21_MOUSE
NC score	0.354207 (rank : 19)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	108	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR14_HUMAN
NC score	0.336652 (rank : 20)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	149	Shared Neighborhood Hits	29
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR23_MOUSE
NC score	0.214525 (rank : 21)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	36	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR26_MOUSE
NC score	0.210163 (rank : 22)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	36	Target Neighborhood Hits	106	Shared Neighborhood Hits	22
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR16_MOUSE
NC score	0.205444 (rank : 23)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	36	Target Neighborhood Hits	178	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR7_HUMAN
NC score	0.203737 (rank : 24)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	36	Target Neighborhood Hits	120	Shared Neighborhood Hits	19
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR16_HUMAN
NC score	0.201082 (rank : 25)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	183	Shared Neighborhood Hits	23
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR22_MOUSE
NC score	0.199355 (rank : 26)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	36	Target Neighborhood Hits	97	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR7_MOUSE
NC score	0.193143 (rank : 27)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	36	Target Neighborhood Hits	112	Shared Neighborhood Hits	19
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR6_MOUSE
NC score	0.182922 (rank : 28)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	36	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR8_HUMAN
NC score	0.180272 (rank : 29)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	36	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR6_HUMAN
NC score	0.169863 (rank : 30)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	36	Target Neighborhood Hits	95	Shared Neighborhood Hits	19
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR1A_MOUSE
NC score	0.165519 (rank : 31)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	36	Target Neighborhood Hits	131	Shared Neighborhood Hits	17
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR8_MOUSE
NC score	0.164863 (rank : 32)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	36	Target Neighborhood Hits	208	Shared Neighborhood Hits	25
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR1A_HUMAN
NC score	0.149587 (rank : 33)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	36	Target Neighborhood Hits	121	Shared Neighborhood Hits	18
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

EDAR_MOUSE
NC score	0.146203 (rank : 34)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	66	Shared Neighborhood Hits	16
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

TNR25_HUMAN
NC score	0.145582 (rank : 35)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	36	Target Neighborhood Hits	172	Shared Neighborhood Hits	21
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TR19L_HUMAN
NC score	0.136828 (rank : 36)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	36	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR10C_HUMAN
NC score	0.123617 (rank : 37)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	36	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR19_MOUSE
NC score	0.120331 (rank : 38)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	36	Target Neighborhood Hits	100	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

EDAR_HUMAN
NC score	0.120125 (rank : 39)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

TNR27_HUMAN
NC score	0.114118 (rank : 40)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TR19L_MOUSE
NC score	0.110443 (rank : 41)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	36	Target Neighborhood Hits	85	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TR10A_HUMAN
NC score	0.110091 (rank : 42)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	36	Target Neighborhood Hits	82	Shared Neighborhood Hits	16
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_HUMAN
NC score	0.108244 (rank : 43)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	36	Target Neighborhood Hits	71	Shared Neighborhood Hits	17
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10D_HUMAN
NC score	0.105926 (rank : 44)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	36	Target Neighborhood Hits	62	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10B_MOUSE
NC score	0.095167 (rank : 45)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	36	Target Neighborhood Hits	76	Shared Neighborhood Hits	13
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR27_MOUSE
NC score	0.092284 (rank : 46)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	36	Target Neighborhood Hits	61	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR19_HUMAN
NC score	0.080795 (rank : 47)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	36	Target Neighborhood Hits	89	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

MT3_MOUSE
NC score	0.069546 (rank : 48)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

KRA93_HUMAN
NC score	0.033883 (rank : 49)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	203	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

STAB2_HUMAN
NC score	0.029559 (rank : 50)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	534	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
NC score	0.028576 (rank : 51)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	528	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CRIM1_HUMAN
NC score	0.026837 (rank : 52)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	362	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

GRN_HUMAN
NC score	0.026577 (rank : 53)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	268	Shared Neighborhood Hits	12
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KRA98_HUMAN
NC score	0.026403 (rank : 54)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	185	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

TSP4_MOUSE
NC score	0.026271 (rank : 55)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	276	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_HUMAN
NC score	0.022962 (rank : 56)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	277	Shared Neighborhood Hits	9
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

FBN1_HUMAN
NC score	0.022422 (rank : 57)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	557	Shared Neighborhood Hits	22
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

TS1R2_MOUSE
NC score	0.022053 (rank : 58)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

PGBM_MOUSE
NC score	0.020529 (rank : 59)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	1073	Shared Neighborhood Hits	26
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NOTC1_HUMAN
NC score	0.015305 (rank : 60)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	906	Shared Neighborhood Hits	14
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ZDH15_MOUSE
NC score	0.012112 (rank : 61)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGJ0, Q3TV63, Q8BMB7	Gene names	Zdhhc15
Domain Architecture	No domain graphic available
Description	Palmitoyltransferase ZDHHC15 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 15) (DHHC-15).

ZDH15_HUMAN
NC score	0.012069 (rank : 62)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	Q96MV8, Q3SY30, Q6UWH3	Gene names	ZDHHC15
Domain Architecture
Description	Palmitoyltransferase ZDHHC15 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 15) (DHHC-15).