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Network neighborhood for query Sequence : TR10A_HUMAN

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TR10A_HUMAN
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TR10A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_HUMAN
θ value	4.96919e-91 (rank : 2)	NC score	0.943151 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10D_HUMAN
θ value	2.65329e-68 (rank : 3)	NC score	0.930347 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10B_MOUSE
θ value	2.49495e-50 (rank : 4)	NC score	0.873149 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR10C_HUMAN
θ value	1.73182e-43 (rank : 5)	NC score	0.905580 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR6_HUMAN
θ value	8.67504e-11 (rank : 6)	NC score	0.611339 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR22_MOUSE
θ value	5.62301e-10 (rank : 7)	NC score	0.646803 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	97	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR26_MOUSE
θ value	9.59137e-10 (rank : 8)	NC score	0.643780 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	106	Shared Neighborhood Hits	42
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR23_MOUSE
θ value	8.11959e-09 (rank : 9)	NC score	0.613961 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR6_MOUSE
θ value	3.08544e-08 (rank : 10)	NC score	0.591165 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR1B_HUMAN
θ value	1.53129e-07 (rank : 11)	NC score	0.500846 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	127	Shared Neighborhood Hits	47
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TR11B_HUMAN
θ value	7.59969e-07 (rank : 12)	NC score	0.509269 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	92	Shared Neighborhood Hits	44
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR3_HUMAN
θ value	2.21117e-06 (rank : 13)	NC score	0.479163 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	145	Shared Neighborhood Hits	49
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR6B_HUMAN
θ value	3.77169e-06 (rank : 14)	NC score	0.446798 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR8_HUMAN
θ value	6.43352e-06 (rank : 15)	NC score	0.465492 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR16_MOUSE
θ value	8.40245e-06 (rank : 16)	NC score	0.495236 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR4_MOUSE
θ value	1.09739e-05 (rank : 17)	NC score	0.482420 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR16_HUMAN
θ value	4.1701e-05 (rank : 18)	NC score	0.495244 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	183	Shared Neighborhood Hits	56
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR1B_MOUSE
θ value	9.29e-05 (rank : 19)	NC score	0.474195 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	123	Shared Neighborhood Hits	44
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR21_HUMAN
θ value	9.29e-05 (rank : 20)	NC score	0.427900 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR4_HUMAN
θ value	0.000121331 (rank : 21)	NC score	0.478581 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	152	Shared Neighborhood Hits	50
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TR11B_MOUSE
θ value	0.000121331 (rank : 22)	NC score	0.488177 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

SCUB3_MOUSE
θ value	0.000158464 (rank : 23)	NC score	0.103860 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	442	Shared Neighborhood Hits	55
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TNR21_MOUSE
θ value	0.000158464 (rank : 24)	NC score	0.413163 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR1A_HUMAN
θ value	0.00020696 (rank : 25)	NC score	0.497637 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	121	Shared Neighborhood Hits	47
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR1A_MOUSE
θ value	0.00020696 (rank : 26)	NC score	0.467072 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

SCUB3_HUMAN
θ value	0.000270298 (rank : 27)	NC score	0.104792 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	428	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TNR8_MOUSE
θ value	0.000602161 (rank : 28)	NC score	0.428906 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	208	Shared Neighborhood Hits	40
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

ANK3_HUMAN
θ value	0.00228821 (rank : 29)	NC score	0.045884 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	853	Shared Neighborhood Hits	13
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

TNR3_MOUSE
θ value	0.00228821 (rank : 30)	NC score	0.428278 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	113	Shared Neighborhood Hits	46
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR14_HUMAN
θ value	0.00298849 (rank : 31)	NC score	0.495047 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

COMP_MOUSE
θ value	0.0193708 (rank : 32)	NC score	0.063754 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CILP1_MOUSE
θ value	0.0252991 (rank : 33)	NC score	0.040954 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	282	Shared Neighborhood Hits	3
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

EPHB4_HUMAN
θ value	0.0252991 (rank : 34)	NC score	0.026605 (rank : 90)
Query Neighborhood Hits	82	Target Neighborhood Hits	1056	Shared Neighborhood Hits	32
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

PCSK5_HUMAN
θ value	0.0431538 (rank : 35)	NC score	0.100070 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	291	Shared Neighborhood Hits	47
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

TNR9_HUMAN
θ value	0.0431538 (rank : 36)	NC score	0.348637 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	166	Shared Neighborhood Hits	50
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

USH2A_HUMAN
θ value	0.0563607 (rank : 37)	NC score	0.064311 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	600	Shared Neighborhood Hits	48
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

COMP_HUMAN
θ value	0.0736092 (rank : 38)	NC score	0.055367 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

PCSK6_HUMAN
θ value	0.0961366 (rank : 39)	NC score	0.084138 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	298	Shared Neighborhood Hits	39
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

TNR9_MOUSE
θ value	0.0961366 (rank : 40)	NC score	0.351781 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

ANK1_MOUSE
θ value	0.125558 (rank : 41)	NC score	0.036959 (rank : 86)
Query Neighborhood Hits	82	Target Neighborhood Hits	430	Shared Neighborhood Hits	8
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

TNR7_HUMAN
θ value	0.163984 (rank : 42)	NC score	0.373283 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	120	Shared Neighborhood Hits	47
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

ZAN_MOUSE
θ value	0.163984 (rank : 43)	NC score	0.079968 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	808	Shared Neighborhood Hits	50
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

EPHA2_MOUSE
θ value	0.279714 (rank : 44)	NC score	0.022297 (rank : 92)
Query Neighborhood Hits	82	Target Neighborhood Hits	1020	Shared Neighborhood Hits	28
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

ANK1_HUMAN
θ value	0.365318 (rank : 45)	NC score	0.035613 (rank : 87)
Query Neighborhood Hits	82	Target Neighborhood Hits	416	Shared Neighborhood Hits	8
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

PAK4_MOUSE
θ value	0.365318 (rank : 46)	NC score	0.005955 (rank : 103)
Query Neighborhood Hits	82	Target Neighborhood Hits	1098	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PCSK5_MOUSE
θ value	0.365318 (rank : 47)	NC score	0.121861 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	613	Shared Neighborhood Hits	57
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TOIP2_HUMAN
θ value	0.365318 (rank : 48)	NC score	0.038056 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

ANK2_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.039193 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	1615	Shared Neighborhood Hits	14
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

EPHB6_HUMAN
θ value	1.06291 (rank : 50)	NC score	0.027487 (rank : 89)
Query Neighborhood Hits	82	Target Neighborhood Hits	912	Shared Neighborhood Hits	28
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

NELL1_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.044780 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	451	Shared Neighborhood Hits	31
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SREC_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.062199 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	645	Shared Neighborhood Hits	47
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

TNR25_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.371496 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	172	Shared Neighborhood Hits	48
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

LAMA1_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.053655 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	838	Shared Neighborhood Hits	54
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

SREC2_MOUSE
θ value	1.81305 (rank : 55)	NC score	0.052046 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	605	Shared Neighborhood Hits	42
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

MEGF8_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.063837 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	528	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TNR5_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.364736 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

USH2A_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.062235 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	626	Shared Neighborhood Hits	50
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

FBLN2_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.042673 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	392	Shared Neighborhood Hits	27
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

TNR7_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.322326 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	112	Shared Neighborhood Hits	41
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

AQR_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.016127 (rank : 97)
Query Neighborhood Hits	82	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

EPHA4_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.016186 (rank : 95)
Query Neighborhood Hits	82	Target Neighborhood Hits	975	Shared Neighborhood Hits	20
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
θ value	4.03905 (rank : 63)	NC score	0.016156 (rank : 96)
Query Neighborhood Hits	82	Target Neighborhood Hits	982	Shared Neighborhood Hits	21
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHB6_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.024703 (rank : 91)
Query Neighborhood Hits	82	Target Neighborhood Hits	906	Shared Neighborhood Hits	27
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

LAMA5_MOUSE
θ value	4.03905 (rank : 65)	NC score	0.063945 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	828	Shared Neighborhood Hits	57
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NC6IP_MOUSE
θ value	4.03905 (rank : 66)	NC score	0.017534 (rank : 93)
Query Neighborhood Hits	82	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q923W1, Q6DI60, Q6PEA7, Q8R0W9	Gene names	Ncoa6ip, Pimt
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT).

RIPK1_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.013152 (rank : 99)
Query Neighborhood Hits	82	Target Neighborhood Hits	891	Shared Neighborhood Hits	21
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

DPF1_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.005808 (rank : 104)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

EPHA2_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.017088 (rank : 94)
Query Neighborhood Hits	82	Target Neighborhood Hits	1021	Shared Neighborhood Hits	23
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

LAMC2_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.051900 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	715	Shared Neighborhood Hits	50
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

PGBM_MOUSE
θ value	5.27518 (rank : 71)	NC score	0.037177 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	1073	Shared Neighborhood Hits	48
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ZN516_MOUSE
θ value	5.27518 (rank : 72)	NC score	-0.001656 (rank : 107)
Query Neighborhood Hits	82	Target Neighborhood Hits	1197	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

FBLN2_MOUSE
θ value	6.88961 (rank : 73)	NC score	0.039086 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	505	Shared Neighborhood Hits	29
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LHX61_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.002763 (rank : 105)
Query Neighborhood Hits	82	Target Neighborhood Hits	396	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1R0, Q9R1R1	Gene names	Lhx6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1.

MY18B_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.001922 (rank : 106)
Query Neighborhood Hits	82	Target Neighborhood Hits	1299	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CF047_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.013737 (rank : 98)
Query Neighborhood Hits	82	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1R4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf47 homolog.

CN133_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.012130 (rank : 100)
Query Neighborhood Hits	82	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGQ1, Q8BL55, Q8CIK4, Q91YI3	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf133 homolog.

FBN3_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.042816 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	543	Shared Neighborhood Hits	38
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

MEGF8_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.056593 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	520	Shared Neighborhood Hits	35
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MT1G_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.027492 (rank : 88)
Query Neighborhood Hits	82	Target Neighborhood Hits	63	Shared Neighborhood Hits	12
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MTSS1_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.012057 (rank : 101)
Query Neighborhood Hits	82	Target Neighborhood Hits	504	Shared Neighborhood Hits	3
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.011731 (rank : 102)
Query Neighborhood Hits	82	Target Neighborhood Hits	592	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

EDAR_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.052362 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

FRAS1_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.058787 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	759	Shared Neighborhood Hits	48
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.053624 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	747	Shared Neighborhood Hits	46
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA1_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.052993 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	804	Shared Neighborhood Hits	50
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA5_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.067032 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	976	Shared Neighborhood Hits	56
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.050054 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	692	Shared Neighborhood Hits	42
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.050966 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	722	Shared Neighborhood Hits	46
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC1_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.052271 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	922	Shared Neighborhood Hits	49
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.059519 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	614	Shared Neighborhood Hits	54
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.060825 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	588	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.081166 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	624	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEGF6_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.051121 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	671	Shared Neighborhood Hits	48
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF9_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.062737 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	557	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.060608 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	896	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TNR11_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.298817 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	135	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.285037 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	121	Shared Neighborhood Hits	40
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR18_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.150032 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR18_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.110091 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR19_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.079879 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	89	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.110715 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR27_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.134995 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	69	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR27_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.108363 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR5_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.333409 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TR19L_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.101436 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.106028 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

Hits sorted by NC score

TR10A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_HUMAN
NC score	0.943151 (rank : 2)	θ value	4.96919e-91 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10D_HUMAN
NC score	0.930347 (rank : 3)	θ value	2.65329e-68 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10C_HUMAN
NC score	0.905580 (rank : 4)	θ value	1.73182e-43 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	105	Shared Neighborhood Hits	46
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR10B_MOUSE
NC score	0.873149 (rank : 5)	θ value	2.49495e-50 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	76	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR22_MOUSE
NC score	0.646803 (rank : 6)	θ value	5.62301e-10 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	97	Shared Neighborhood Hits	45
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR26_MOUSE
NC score	0.643780 (rank : 7)	θ value	9.59137e-10 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	106	Shared Neighborhood Hits	42
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR23_MOUSE
NC score	0.613961 (rank : 8)	θ value	8.11959e-09 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR6_HUMAN
NC score	0.611339 (rank : 9)	θ value	8.67504e-11 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
NC score	0.591165 (rank : 10)	θ value	3.08544e-08 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TR11B_HUMAN
NC score	0.509269 (rank : 11)	θ value	7.59969e-07 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	92	Shared Neighborhood Hits	44
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR1B_HUMAN
NC score	0.500846 (rank : 12)	θ value	1.53129e-07 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	127	Shared Neighborhood Hits	47
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1A_HUMAN
NC score	0.497637 (rank : 13)	θ value	0.00020696 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	121	Shared Neighborhood Hits	47
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR16_HUMAN
NC score	0.495244 (rank : 14)	θ value	4.1701e-05 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	183	Shared Neighborhood Hits	56
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
NC score	0.495236 (rank : 15)	θ value	8.40245e-06 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	178	Shared Neighborhood Hits	54
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR14_HUMAN
NC score	0.495047 (rank : 16)	θ value	0.00298849 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	149	Shared Neighborhood Hits	50
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TR11B_MOUSE
NC score	0.488177 (rank : 17)	θ value	0.000121331 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	95	Shared Neighborhood Hits	46
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR4_MOUSE
NC score	0.482420 (rank : 18)	θ value	1.09739e-05 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR3_HUMAN
NC score	0.479163 (rank : 19)	θ value	2.21117e-06 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	145	Shared Neighborhood Hits	49
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR4_HUMAN
NC score	0.478581 (rank : 20)	θ value	0.000121331 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	152	Shared Neighborhood Hits	50
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR1B_MOUSE
NC score	0.474195 (rank : 21)	θ value	9.29e-05 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	123	Shared Neighborhood Hits	44
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR1A_MOUSE
NC score	0.467072 (rank : 22)	θ value	0.00020696 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR8_HUMAN
NC score	0.465492 (rank : 23)	θ value	6.43352e-06 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR6B_HUMAN
NC score	0.446798 (rank : 24)	θ value	3.77169e-06 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	103	Shared Neighborhood Hits	43
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR8_MOUSE
NC score	0.428906 (rank : 25)	θ value	0.000602161 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	208	Shared Neighborhood Hits	40
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR3_MOUSE
NC score	0.428278 (rank : 26)	θ value	0.00228821 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	113	Shared Neighborhood Hits	46
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR21_HUMAN
NC score	0.427900 (rank : 27)	θ value	9.29e-05 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	90	Shared Neighborhood Hits	39
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
NC score	0.413163 (rank : 28)	θ value	0.000158464 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR7_HUMAN
NC score	0.373283 (rank : 29)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	120	Shared Neighborhood Hits	47
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR25_HUMAN
NC score	0.371496 (rank : 30)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	172	Shared Neighborhood Hits	48
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR5_MOUSE
NC score	0.364736 (rank : 31)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	131	Shared Neighborhood Hits	45
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR9_MOUSE
NC score	0.351781 (rank : 32)	θ value	0.0961366 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	137	Shared Neighborhood Hits	49
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR9_HUMAN
NC score	0.348637 (rank : 33)	θ value	0.0431538 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	166	Shared Neighborhood Hits	50
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR5_HUMAN
NC score	0.333409 (rank : 34)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	82	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR7_MOUSE
NC score	0.322326 (rank : 35)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	112	Shared Neighborhood Hits	41
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR11_HUMAN
NC score	0.298817 (rank : 36)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	82	Target Neighborhood Hits	135	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
NC score	0.285037 (rank : 37)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	82	Target Neighborhood Hits	121	Shared Neighborhood Hits	40
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR18_HUMAN
NC score	0.150032 (rank : 38)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	82	Target Neighborhood Hits	55	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR27_HUMAN
NC score	0.134995 (rank : 39)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	82	Target Neighborhood Hits	69	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

PCSK5_MOUSE
NC score	0.121861 (rank : 40)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	613	Shared Neighborhood Hits	57
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TNR19_MOUSE
NC score	0.110715 (rank : 41)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	82	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR18_MOUSE
NC score	0.110091 (rank : 42)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	82	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR27_MOUSE
NC score	0.108363 (rank : 43)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	82	Target Neighborhood Hits	61	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TR19L_MOUSE
NC score	0.106028 (rank : 44)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	82	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

SCUB3_HUMAN
NC score	0.104792 (rank : 45)	θ value	0.000270298 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	428	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
NC score	0.103860 (rank : 46)	θ value	0.000158464 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	442	Shared Neighborhood Hits	55
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TR19L_HUMAN
NC score	0.101436 (rank : 47)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	82	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

PCSK5_HUMAN
NC score	0.100070 (rank : 48)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	291	Shared Neighborhood Hits	47
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK6_HUMAN
NC score	0.084138 (rank : 49)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	298	Shared Neighborhood Hits	39
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

LAMC3_MOUSE
NC score	0.081166 (rank : 50)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	82	Target Neighborhood Hits	624	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

ZAN_MOUSE
NC score	0.079968 (rank : 51)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	808	Shared Neighborhood Hits	50
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

TNR19_HUMAN
NC score	0.079879 (rank : 52)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	82	Target Neighborhood Hits	89	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

LAMA5_HUMAN
NC score	0.067032 (rank : 53)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	82	Target Neighborhood Hits	976	Shared Neighborhood Hits	56
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

USH2A_HUMAN
NC score	0.064311 (rank : 54)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	600	Shared Neighborhood Hits	48
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LAMA5_MOUSE
NC score	0.063945 (rank : 55)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	828	Shared Neighborhood Hits	57
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MEGF8_HUMAN
NC score	0.063837 (rank : 56)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	528	Shared Neighborhood Hits	38
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

COMP_MOUSE
NC score	0.063754 (rank : 57)	θ value	0.0193708 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

MEGF9_HUMAN
NC score	0.062737 (rank : 58)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	82	Target Neighborhood Hits	557	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

USH2A_MOUSE
NC score	0.062235 (rank : 59)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	626	Shared Neighborhood Hits	50
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

SREC_HUMAN
NC score	0.062199 (rank : 60)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	645	Shared Neighborhood Hits	47
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LAMC3_HUMAN
NC score	0.060825 (rank : 61)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	82	Target Neighborhood Hits	588	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEGF9_MOUSE
NC score	0.060608 (rank : 62)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	82	Target Neighborhood Hits	896	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMC2_MOUSE
NC score	0.059519 (rank : 63)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	82	Target Neighborhood Hits	614	Shared Neighborhood Hits	54
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

FRAS1_HUMAN
NC score	0.058787 (rank : 64)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	759	Shared Neighborhood Hits	48
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF8_MOUSE
NC score	0.056593 (rank : 65)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	520	Shared Neighborhood Hits	35
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

COMP_HUMAN
NC score	0.055367 (rank : 66)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	258	Shared Neighborhood Hits	24
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

LAMA1_MOUSE
NC score	0.053655 (rank : 67)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	838	Shared Neighborhood Hits	54
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

FRAS1_MOUSE
NC score	0.053624 (rank : 68)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	747	Shared Neighborhood Hits	46
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA1_HUMAN
NC score	0.052993 (rank : 69)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	82	Target Neighborhood Hits	804	Shared Neighborhood Hits	50
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

EDAR_MOUSE
NC score	0.052362 (rank : 70)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	66	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

LAMC1_HUMAN
NC score	0.052271 (rank : 71)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	82	Target Neighborhood Hits	922	Shared Neighborhood Hits	49
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SREC2_MOUSE
NC score	0.052046 (rank : 72)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	605	Shared Neighborhood Hits	42
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

LAMC2_HUMAN
NC score	0.051900 (rank : 73)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	715	Shared Neighborhood Hits	50
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

MEGF6_HUMAN
NC score	0.051121 (rank : 74)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	82	Target Neighborhood Hits	671	Shared Neighborhood Hits	48
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LAMB2_MOUSE
NC score	0.050966 (rank : 75)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	82	Target Neighborhood Hits	722	Shared Neighborhood Hits	46
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB2_HUMAN
NC score	0.050054 (rank : 76)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	82	Target Neighborhood Hits	692	Shared Neighborhood Hits	42
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

ANK3_HUMAN
NC score	0.045884 (rank : 77)	θ value	0.00228821 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	853	Shared Neighborhood Hits	13
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

NELL1_HUMAN
NC score	0.044780 (rank : 78)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	451	Shared Neighborhood Hits	31
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

FBN3_HUMAN
NC score	0.042816 (rank : 79)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	543	Shared Neighborhood Hits	38
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBLN2_HUMAN
NC score	0.042673 (rank : 80)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	392	Shared Neighborhood Hits	27
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

CILP1_MOUSE
NC score	0.040954 (rank : 81)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	282	Shared Neighborhood Hits	3
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

ANK2_HUMAN
NC score	0.039193 (rank : 82)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	1615	Shared Neighborhood Hits	14
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

FBLN2_MOUSE
NC score	0.039086 (rank : 83)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	505	Shared Neighborhood Hits	29
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

TOIP2_HUMAN
NC score	0.038056 (rank : 84)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

PGBM_MOUSE
NC score	0.037177 (rank : 85)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	1073	Shared Neighborhood Hits	48
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ANK1_MOUSE
NC score	0.036959 (rank : 86)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	430	Shared Neighborhood Hits	8
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANK1_HUMAN
NC score	0.035613 (rank : 87)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	416	Shared Neighborhood Hits	8
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

MT1G_HUMAN
NC score	0.027492 (rank : 88)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	63	Shared Neighborhood Hits	12
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

EPHB6_HUMAN
NC score	0.027487 (rank : 89)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	912	Shared Neighborhood Hits	28
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHB4_HUMAN
NC score	0.026605 (rank : 90)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	1056	Shared Neighborhood Hits	32
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB6_MOUSE
NC score	0.024703 (rank : 91)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	906	Shared Neighborhood Hits	27
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHA2_MOUSE
NC score	0.022297 (rank : 92)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	1020	Shared Neighborhood Hits	28
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

NC6IP_MOUSE
NC score	0.017534 (rank : 93)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q923W1, Q6DI60, Q6PEA7, Q8R0W9	Gene names	Ncoa6ip, Pimt
Domain Architecture	No domain graphic available
Description	Putative RNA methyltransferase NCOA6IP (EC 2.1.1.-) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIPMT) (PIMT).

EPHA2_HUMAN
NC score	0.017088 (rank : 94)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	1021	Shared Neighborhood Hits	23
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA4_HUMAN
NC score	0.016186 (rank : 95)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	975	Shared Neighborhood Hits	20
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA4_MOUSE
NC score	0.016156 (rank : 96)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	982	Shared Neighborhood Hits	21
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

AQR_HUMAN
NC score	0.016127 (rank : 97)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

CF047_MOUSE
NC score	0.013737 (rank : 98)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1R4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf47 homolog.

RIPK1_HUMAN
NC score	0.013152 (rank : 99)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	891	Shared Neighborhood Hits	21
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

CN133_MOUSE
NC score	0.012130 (rank : 100)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGQ1, Q8BL55, Q8CIK4, Q91YI3	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf133 homolog.

MTSS1_HUMAN
NC score	0.012057 (rank : 101)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	504	Shared Neighborhood Hits	3
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
NC score	0.011731 (rank : 102)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	592	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PAK4_MOUSE
NC score	0.005955 (rank : 103)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	1098	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

DPF1_MOUSE
NC score	0.005808 (rank : 104)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	491	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

LHX61_MOUSE
NC score	0.002763 (rank : 105)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	396	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1R0, Q9R1R1	Gene names	Lhx6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1.

MY18B_HUMAN
NC score	0.001922 (rank : 106)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	1299	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

ZN516_MOUSE
NC score	-0.001656 (rank : 107)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	1197	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.