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Network neighborhood for query Sequence : PCSK6_HUMAN

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PCSK6_HUMAN
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FURIN_HUMAN
θ value	0 (rank : 1)	NC score	0.903218 (rank : 4)
Query Neighborhood Hits	298	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

FURIN_MOUSE
θ value	0 (rank : 2)	NC score	0.904758 (rank : 3)
Query Neighborhood Hits	298	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

PCSK5_HUMAN
θ value	0 (rank : 3)	NC score	0.958747 (rank : 2)
Query Neighborhood Hits	298	Target Neighborhood Hits	291	Shared Neighborhood Hits	177
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK5_MOUSE
θ value	0 (rank : 4)	NC score	0.883122 (rank : 6)
Query Neighborhood Hits	298	Target Neighborhood Hits	613	Shared Neighborhood Hits	217
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK6_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	298	Target Neighborhood Hits	298	Shared Neighborhood Hits	298
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PCSK4_HUMAN
θ value	2.49359e-167 (rank : 6)	NC score	0.890260 (rank : 5)
Query Neighborhood Hits	298	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

NEC1_HUMAN
θ value	3.25673e-167 (rank : 7)	NC score	0.875905 (rank : 8)
Query Neighborhood Hits	298	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

NEC1_MOUSE
θ value	1.23756e-166 (rank : 8)	NC score	0.875740 (rank : 9)
Query Neighborhood Hits	298	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	P63239, P21662, P22546	Gene names	Pcsk1, Att-1, Nec-1, Nec1
Domain Architecture	No domain graphic available
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1) (PC3) (Furin homolog) (Propeptide-processing protease).

PCSK4_MOUSE
θ value	4.86655e-163 (rank : 9)	NC score	0.878385 (rank : 7)
Query Neighborhood Hits	298	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

NEC2_HUMAN
θ value	3.62588e-142 (rank : 10)	NC score	0.872262 (rank : 11)
Query Neighborhood Hits	298	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P16519, Q14927, Q9NQG3, Q9NUG1, Q9UJC6	Gene names	PCSK2, NEC2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NEC2_MOUSE
θ value	3.06949e-141 (rank : 11)	NC score	0.872443 (rank : 10)
Query Neighborhood Hits	298	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P21661, Q80WU1	Gene names	Pcsk2, Nec-2, Nec2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

PCSK7_MOUSE
θ value	3.89193e-128 (rank : 12)	NC score	0.864788 (rank : 13)
Query Neighborhood Hits	298	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

PCSK7_HUMAN
θ value	1.05987e-125 (rank : 13)	NC score	0.864868 (rank : 12)
Query Neighborhood Hits	298	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

FRAS1_MOUSE
θ value	1.6813e-30 (rank : 14)	NC score	0.380325 (rank : 15)
Query Neighborhood Hits	298	Target Neighborhood Hits	747	Shared Neighborhood Hits	211
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_HUMAN
θ value	1.08979e-29 (rank : 15)	NC score	0.386391 (rank : 14)
Query Neighborhood Hits	298	Target Neighborhood Hits	759	Shared Neighborhood Hits	213
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CREL1_HUMAN
θ value	2.98157e-11 (rank : 16)	NC score	0.312117 (rank : 23)
Query Neighborhood Hits	298	Target Neighborhood Hits	441	Shared Neighborhood Hits	159
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	2.98157e-11 (rank : 17)	NC score	0.310883 (rank : 24)
Query Neighborhood Hits	298	Target Neighborhood Hits	524	Shared Neighborhood Hits	172
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

RSPO3_HUMAN
θ value	2.52405e-10 (rank : 18)	NC score	0.346145 (rank : 16)
Query Neighborhood Hits	298	Target Neighborhood Hits	128	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	4.30538e-10 (rank : 19)	NC score	0.340776 (rank : 17)
Query Neighborhood Hits	298	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

ERBB3_HUMAN
θ value	9.59137e-10 (rank : 20)	NC score	0.112880 (rank : 273)
Query Neighborhood Hits	298	Target Neighborhood Hits	918	Shared Neighborhood Hits	75
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB4_HUMAN
θ value	1.63604e-09 (rank : 21)	NC score	0.102479 (rank : 306)
Query Neighborhood Hits	298	Target Neighborhood Hits	910	Shared Neighborhood Hits	74
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

RSPO4_MOUSE
θ value	1.63604e-09 (rank : 22)	NC score	0.331780 (rank : 19)
Query Neighborhood Hits	298	Target Neighborhood Hits	110	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SREC2_HUMAN
θ value	2.13673e-09 (rank : 23)	NC score	0.293179 (rank : 27)
Query Neighborhood Hits	298	Target Neighborhood Hits	645	Shared Neighborhood Hits	179
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	2.79066e-09 (rank : 24)	NC score	0.295752 (rank : 26)
Query Neighborhood Hits	298	Target Neighborhood Hits	605	Shared Neighborhood Hits	182
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

EGFR_HUMAN
θ value	3.64472e-09 (rank : 25)	NC score	0.096222 (rank : 321)
Query Neighborhood Hits	298	Target Neighborhood Hits	939	Shared Neighborhood Hits	79
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

ERBB2_HUMAN
θ value	3.64472e-09 (rank : 26)	NC score	0.098693 (rank : 316)
Query Neighborhood Hits	298	Target Neighborhood Hits	1073	Shared Neighborhood Hits	60
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
θ value	3.64472e-09 (rank : 27)	NC score	0.098561 (rank : 317)
Query Neighborhood Hits	298	Target Neighborhood Hits	918	Shared Neighborhood Hits	60
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_MOUSE
θ value	6.21693e-09 (rank : 28)	NC score	0.111366 (rank : 281)
Query Neighborhood Hits	298	Target Neighborhood Hits	898	Shared Neighborhood Hits	70
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

RSPO4_HUMAN
θ value	6.21693e-09 (rank : 29)	NC score	0.334053 (rank : 18)
Query Neighborhood Hits	298	Target Neighborhood Hits	110	Shared Neighborhood Hits	68
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

EGFR_MOUSE
θ value	1.06045e-08 (rank : 30)	NC score	0.097275 (rank : 319)
Query Neighborhood Hits	298	Target Neighborhood Hits	927	Shared Neighborhood Hits	85
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

RSPO1_HUMAN
θ value	1.38499e-08 (rank : 31)	NC score	0.312790 (rank : 22)
Query Neighborhood Hits	298	Target Neighborhood Hits	101	Shared Neighborhood Hits	56
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO1_MOUSE
θ value	2.36244e-08 (rank : 32)	NC score	0.296244 (rank : 25)
Query Neighborhood Hits	298	Target Neighborhood Hits	85	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

LAMB1_MOUSE
θ value	4.0297e-08 (rank : 33)	NC score	0.232206 (rank : 51)
Query Neighborhood Hits	298	Target Neighborhood Hits	919	Shared Neighborhood Hits	157
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SREC_HUMAN
θ value	5.26297e-08 (rank : 34)	NC score	0.292256 (rank : 28)
Query Neighborhood Hits	298	Target Neighborhood Hits	645	Shared Neighborhood Hits	181
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

MEGF9_MOUSE
θ value	7.59969e-07 (rank : 35)	NC score	0.280043 (rank : 31)
Query Neighborhood Hits	298	Target Neighborhood Hits	896	Shared Neighborhood Hits	177
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF6_HUMAN
θ value	9.92553e-07 (rank : 36)	NC score	0.269721 (rank : 33)
Query Neighborhood Hits	298	Target Neighborhood Hits	671	Shared Neighborhood Hits	189
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

RSPO2_HUMAN
θ value	9.92553e-07 (rank : 37)	NC score	0.317999 (rank : 21)
Query Neighborhood Hits	298	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	1.29631e-06 (rank : 38)	NC score	0.318209 (rank : 20)
Query Neighborhood Hits	298	Target Neighborhood Hits	88	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

INSRR_HUMAN
θ value	6.43352e-06 (rank : 39)	NC score	0.090238 (rank : 333)
Query Neighborhood Hits	298	Target Neighborhood Hits	950	Shared Neighborhood Hits	92
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	1.09739e-05 (rank : 40)	NC score	0.089137 (rank : 337)
Query Neighborhood Hits	298	Target Neighborhood Hits	961	Shared Neighborhood Hits	104
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

ATS17_HUMAN
θ value	1.87187e-05 (rank : 41)	NC score	0.056429 (rank : 429)
Query Neighborhood Hits	298	Target Neighborhood Hits	194	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

IGF1R_HUMAN
θ value	2.44474e-05 (rank : 42)	NC score	0.084840 (rank : 347)
Query Neighborhood Hits	298	Target Neighborhood Hits	977	Shared Neighborhood Hits	87
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

LAMB2_HUMAN
θ value	4.1701e-05 (rank : 43)	NC score	0.248231 (rank : 40)
Query Neighborhood Hits	298	Target Neighborhood Hits	692	Shared Neighborhood Hits	167
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

SCUB3_HUMAN
θ value	5.44631e-05 (rank : 44)	NC score	0.209246 (rank : 74)
Query Neighborhood Hits	298	Target Neighborhood Hits	428	Shared Neighborhood Hits	157
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMC3_HUMAN
θ value	7.1131e-05 (rank : 45)	NC score	0.244205 (rank : 44)
Query Neighborhood Hits	298	Target Neighborhood Hits	588	Shared Neighborhood Hits	171
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

SCUB3_MOUSE
θ value	7.1131e-05 (rank : 46)	NC score	0.211031 (rank : 71)
Query Neighborhood Hits	298	Target Neighborhood Hits	442	Shared Neighborhood Hits	162
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

USH2A_MOUSE
θ value	7.1131e-05 (rank : 47)	NC score	0.226534 (rank : 53)
Query Neighborhood Hits	298	Target Neighborhood Hits	626	Shared Neighborhood Hits	167
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

IGF1R_MOUSE
θ value	9.29e-05 (rank : 48)	NC score	0.087161 (rank : 341)
Query Neighborhood Hits	298	Target Neighborhood Hits	973	Shared Neighborhood Hits	87
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

MEGF9_HUMAN
θ value	9.29e-05 (rank : 49)	NC score	0.284976 (rank : 29)
Query Neighborhood Hits	298	Target Neighborhood Hits	557	Shared Neighborhood Hits	168
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

DLL4_MOUSE
θ value	0.000121331 (rank : 50)	NC score	0.202394 (rank : 87)
Query Neighborhood Hits	298	Target Neighborhood Hits	440	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

FBLN2_MOUSE
θ value	0.000121331 (rank : 51)	NC score	0.185592 (rank : 113)
Query Neighborhood Hits	298	Target Neighborhood Hits	505	Shared Neighborhood Hits	134
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LAMA1_MOUSE
θ value	0.000158464 (rank : 52)	NC score	0.239476 (rank : 48)
Query Neighborhood Hits	298	Target Neighborhood Hits	838	Shared Neighborhood Hits	178
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB1_HUMAN
θ value	0.000158464 (rank : 53)	NC score	0.218847 (rank : 60)
Query Neighborhood Hits	298	Target Neighborhood Hits	1018	Shared Neighborhood Hits	158
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

INSR_MOUSE
θ value	0.00020696 (rank : 54)	NC score	0.081215 (rank : 358)
Query Neighborhood Hits	298	Target Neighborhood Hits	968	Shared Neighborhood Hits	78
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

LAMA1_HUMAN
θ value	0.000270298 (rank : 55)	NC score	0.239676 (rank : 46)
Query Neighborhood Hits	298	Target Neighborhood Hits	804	Shared Neighborhood Hits	179
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC3_MOUSE
θ value	0.000270298 (rank : 56)	NC score	0.239098 (rank : 49)
Query Neighborhood Hits	298	Target Neighborhood Hits	624	Shared Neighborhood Hits	176
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEGF8_HUMAN
θ value	0.000270298 (rank : 57)	NC score	0.263279 (rank : 35)
Query Neighborhood Hits	298	Target Neighborhood Hits	528	Shared Neighborhood Hits	165
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

CRUM1_HUMAN
θ value	0.000461057 (rank : 58)	NC score	0.185980 (rank : 112)
Query Neighborhood Hits	298	Target Neighborhood Hits	457	Shared Neighborhood Hits	142
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

MEGF8_MOUSE
θ value	0.000461057 (rank : 59)	NC score	0.258764 (rank : 38)
Query Neighborhood Hits	298	Target Neighborhood Hits	520	Shared Neighborhood Hits	162
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMA2_HUMAN
θ value	0.000602161 (rank : 60)	NC score	0.221325 (rank : 57)
Query Neighborhood Hits	298	Target Neighborhood Hits	1092	Shared Neighborhood Hits	182
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA5_MOUSE
θ value	0.000602161 (rank : 61)	NC score	0.244434 (rank : 43)
Query Neighborhood Hits	298	Target Neighborhood Hits	828	Shared Neighborhood Hits	182
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_MOUSE
θ value	0.000602161 (rank : 62)	NC score	0.243659 (rank : 45)
Query Neighborhood Hits	298	Target Neighborhood Hits	722	Shared Neighborhood Hits	164
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

TECTA_MOUSE
θ value	0.000602161 (rank : 63)	NC score	0.137668 (rank : 201)
Query Neighborhood Hits	298	Target Neighborhood Hits	244	Shared Neighborhood Hits	106
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

ZAN_MOUSE
θ value	0.000602161 (rank : 64)	NC score	0.246341 (rank : 42)
Query Neighborhood Hits	298	Target Neighborhood Hits	808	Shared Neighborhood Hits	188
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

INSR_HUMAN
θ value	0.00102713 (rank : 65)	NC score	0.080979 (rank : 359)
Query Neighborhood Hits	298	Target Neighborhood Hits	963	Shared Neighborhood Hits	85
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

TECTA_HUMAN
θ value	0.00102713 (rank : 66)	NC score	0.128405 (rank : 220)
Query Neighborhood Hits	298	Target Neighborhood Hits	239	Shared Neighborhood Hits	100
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

ZN319_MOUSE
θ value	0.00102713 (rank : 67)	NC score	0.020967 (rank : 475)
Query Neighborhood Hits	298	Target Neighborhood Hits	762	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ERR8	Gene names	Znf319, Zfp319
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

LTB1L_HUMAN
θ value	0.00134147 (rank : 68)	NC score	0.196571 (rank : 94)
Query Neighborhood Hits	298	Target Neighborhood Hits	553	Shared Neighborhood Hits	153
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.00134147 (rank : 69)	NC score	0.196182 (rank : 95)
Query Neighborhood Hits	298	Target Neighborhood Hits	502	Shared Neighborhood Hits	146
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

STAB2_HUMAN
θ value	0.00134147 (rank : 70)	NC score	0.221548 (rank : 56)
Query Neighborhood Hits	298	Target Neighborhood Hits	534	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TNR1A_MOUSE
θ value	0.00134147 (rank : 71)	NC score	0.123868 (rank : 238)
Query Neighborhood Hits	298	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

ZN319_HUMAN
θ value	0.00134147 (rank : 72)	NC score	0.021284 (rank : 473)
Query Neighborhood Hits	298	Target Neighborhood Hits	772	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P2F9	Gene names	ZNF319, KIAA1388
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

LTB1L_MOUSE
θ value	0.00175202 (rank : 73)	NC score	0.192913 (rank : 101)
Query Neighborhood Hits	298	Target Neighborhood Hits	514	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.00175202 (rank : 74)	NC score	0.193767 (rank : 99)
Query Neighborhood Hits	298	Target Neighborhood Hits	479	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

STAB1_HUMAN
θ value	0.00175202 (rank : 75)	NC score	0.223041 (rank : 54)
Query Neighborhood Hits	298	Target Neighborhood Hits	546	Shared Neighborhood Hits	164
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

FBN2_HUMAN
θ value	0.00228821 (rank : 76)	NC score	0.212527 (rank : 68)
Query Neighborhood Hits	298	Target Neighborhood Hits	560	Shared Neighborhood Hits	176
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	0.00228821 (rank : 77)	NC score	0.213644 (rank : 65)
Query Neighborhood Hits	298	Target Neighborhood Hits	543	Shared Neighborhood Hits	171
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LAMA5_HUMAN
θ value	0.00228821 (rank : 78)	NC score	0.239642 (rank : 47)
Query Neighborhood Hits	298	Target Neighborhood Hits	976	Shared Neighborhood Hits	188
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

UROM_MOUSE
θ value	0.00228821 (rank : 79)	NC score	0.177722 (rank : 131)
Query Neighborhood Hits	298	Target Neighborhood Hits	276	Shared Neighborhood Hits	114
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_HUMAN
θ value	0.00298849 (rank : 80)	NC score	0.175796 (rank : 136)
Query Neighborhood Hits	298	Target Neighborhood Hits	284	Shared Neighborhood Hits	116
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

NOTC1_MOUSE
θ value	0.00509761 (rank : 81)	NC score	0.204455 (rank : 84)
Query Neighborhood Hits	298	Target Neighborhood Hits	916	Shared Neighborhood Hits	165
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ATS19_MOUSE
θ value	0.00665767 (rank : 82)	NC score	0.045437 (rank : 447)
Query Neighborhood Hits	298	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

FBN1_HUMAN
θ value	0.00665767 (rank : 83)	NC score	0.213066 (rank : 67)
Query Neighborhood Hits	298	Target Neighborhood Hits	557	Shared Neighborhood Hits	177
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LAMC1_HUMAN
θ value	0.00665767 (rank : 84)	NC score	0.208937 (rank : 76)
Query Neighborhood Hits	298	Target Neighborhood Hits	922	Shared Neighborhood Hits	173
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

PGBM_HUMAN
θ value	0.00665767 (rank : 85)	NC score	0.144649 (rank : 189)
Query Neighborhood Hits	298	Target Neighborhood Hits	1113	Shared Neighborhood Hits	167
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

STAB2_MOUSE
θ value	0.00665767 (rank : 86)	NC score	0.220788 (rank : 58)
Query Neighborhood Hits	298	Target Neighborhood Hits	528	Shared Neighborhood Hits	165
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

ATL3_HUMAN
θ value	0.00869519 (rank : 87)	NC score	0.046636 (rank : 444)
Query Neighborhood Hits	298	Target Neighborhood Hits	414	Shared Neighborhood Hits	36
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

LTBP2_MOUSE
θ value	0.00869519 (rank : 88)	NC score	0.213428 (rank : 66)
Query Neighborhood Hits	298	Target Neighborhood Hits	617	Shared Neighborhood Hits	154
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NID2_HUMAN
θ value	0.00869519 (rank : 89)	NC score	0.165529 (rank : 153)
Query Neighborhood Hits	298	Target Neighborhood Hits	456	Shared Neighborhood Hits	128
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

TENA_HUMAN
θ value	0.00869519 (rank : 90)	NC score	0.176919 (rank : 134)
Query Neighborhood Hits	298	Target Neighborhood Hits	631	Shared Neighborhood Hits	157
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TNR26_MOUSE
θ value	0.00869519 (rank : 91)	NC score	0.123516 (rank : 240)
Query Neighborhood Hits	298	Target Neighborhood Hits	106	Shared Neighborhood Hits	63
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

ZN221_HUMAN
θ value	0.00869519 (rank : 92)	NC score	0.022916 (rank : 463)
Query Neighborhood Hits	298	Target Neighborhood Hits	784	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UK13, Q9P1U8	Gene names	ZNF221
Domain Architecture
Description	Zinc finger protein 221.

CRIM1_HUMAN
θ value	0.0113563 (rank : 93)	NC score	0.231771 (rank : 52)
Query Neighborhood Hits	298	Target Neighborhood Hits	362	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

NELL1_HUMAN
θ value	0.0113563 (rank : 94)	NC score	0.218269 (rank : 61)
Query Neighborhood Hits	298	Target Neighborhood Hits	451	Shared Neighborhood Hits	158
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

VWF_MOUSE
θ value	0.0113563 (rank : 95)	NC score	0.153817 (rank : 173)
Query Neighborhood Hits	298	Target Neighborhood Hits	381	Shared Neighborhood Hits	139
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CELR2_MOUSE
θ value	0.0148317 (rank : 96)	NC score	0.079577 (rank : 363)
Query Neighborhood Hits	298	Target Neighborhood Hits	584	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

KRA55_HUMAN
θ value	0.0148317 (rank : 97)	NC score	0.277759 (rank : 32)
Query Neighborhood Hits	298	Target Neighborhood Hits	257	Shared Neighborhood Hits	112
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA59_HUMAN
θ value	0.0148317 (rank : 98)	NC score	0.266620 (rank : 34)
Query Neighborhood Hits	298	Target Neighborhood Hits	310	Shared Neighborhood Hits	124
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMC1_MOUSE
θ value	0.0148317 (rank : 99)	NC score	0.211563 (rank : 70)
Query Neighborhood Hits	298	Target Neighborhood Hits	856	Shared Neighborhood Hits	168
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

FBN1_MOUSE
θ value	0.0193708 (rank : 100)	NC score	0.212256 (rank : 69)
Query Neighborhood Hits	298	Target Neighborhood Hits	563	Shared Neighborhood Hits	175
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

TIE2_MOUSE
θ value	0.0193708 (rank : 101)	NC score	0.095568 (rank : 323)
Query Neighborhood Hits	298	Target Neighborhood Hits	1204	Shared Neighborhood Hits	140
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

USH2A_HUMAN
θ value	0.0193708 (rank : 102)	NC score	0.208561 (rank : 78)
Query Neighborhood Hits	298	Target Neighborhood Hits	600	Shared Neighborhood Hits	154
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

FHL3_MOUSE
θ value	0.0252991 (rank : 103)	NC score	0.046071 (rank : 445)
Query Neighborhood Hits	298	Target Neighborhood Hits	424	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R059, Q9JLP5, Q9WUH3	Gene names	Fhl3
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

KR10B_HUMAN
θ value	0.0252991 (rank : 104)	NC score	0.164189 (rank : 158)
Query Neighborhood Hits	298	Target Neighborhood Hits	269	Shared Neighborhood Hits	109
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

JAG1_HUMAN
θ value	0.0330416 (rank : 105)	NC score	0.205882 (rank : 81)
Query Neighborhood Hits	298	Target Neighborhood Hits	514	Shared Neighborhood Hits	150
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	0.0330416 (rank : 106)	NC score	0.204121 (rank : 86)
Query Neighborhood Hits	298	Target Neighborhood Hits	518	Shared Neighborhood Hits	151
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

PGBM_MOUSE
θ value	0.0330416 (rank : 107)	NC score	0.151700 (rank : 175)
Query Neighborhood Hits	298	Target Neighborhood Hits	1073	Shared Neighborhood Hits	175
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

STAB1_MOUSE
θ value	0.0330416 (rank : 108)	NC score	0.221819 (rank : 55)
Query Neighborhood Hits	298	Target Neighborhood Hits	566	Shared Neighborhood Hits	163
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TIE1_HUMAN
θ value	0.0330416 (rank : 109)	NC score	0.101327 (rank : 309)
Query Neighborhood Hits	298	Target Neighborhood Hits	1241	Shared Neighborhood Hits	146
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

ATS19_HUMAN
θ value	0.0431538 (rank : 110)	NC score	0.041611 (rank : 448)
Query Neighborhood Hits	298	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

NELL2_HUMAN
θ value	0.0431538 (rank : 111)	NC score	0.210634 (rank : 72)
Query Neighborhood Hits	298	Target Neighborhood Hits	449	Shared Neighborhood Hits	147
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NOTC3_HUMAN
θ value	0.0431538 (rank : 112)	NC score	0.192678 (rank : 102)
Query Neighborhood Hits	298	Target Neighborhood Hits	1062	Shared Neighborhood Hits	165
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TNR16_HUMAN
θ value	0.0431538 (rank : 113)	NC score	0.165426 (rank : 154)
Query Neighborhood Hits	298	Target Neighborhood Hits	183	Shared Neighborhood Hits	87
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR1B_HUMAN
θ value	0.0431538 (rank : 114)	NC score	0.108643 (rank : 286)
Query Neighborhood Hits	298	Target Neighborhood Hits	127	Shared Neighborhood Hits	64
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

EGFL9_HUMAN
θ value	0.0563607 (rank : 115)	NC score	0.183945 (rank : 120)
Query Neighborhood Hits	298	Target Neighborhood Hits	365	Shared Neighborhood Hits	135
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

LAMA2_MOUSE
θ value	0.0563607 (rank : 116)	NC score	0.209655 (rank : 73)
Query Neighborhood Hits	298	Target Neighborhood Hits	1198	Shared Neighborhood Hits	170
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NOTC1_HUMAN
θ value	0.0563607 (rank : 117)	NC score	0.197662 (rank : 92)
Query Neighborhood Hits	298	Target Neighborhood Hits	906	Shared Neighborhood Hits	166
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_MOUSE
θ value	0.0563607 (rank : 118)	NC score	0.190875 (rank : 103)
Query Neighborhood Hits	298	Target Neighborhood Hits	975	Shared Neighborhood Hits	158
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TENX_HUMAN
θ value	0.0563607 (rank : 119)	NC score	0.181115 (rank : 125)
Query Neighborhood Hits	298	Target Neighborhood Hits	789	Shared Neighborhood Hits	158
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

KRA52_HUMAN
θ value	0.0736092 (rank : 120)	NC score	0.248375 (rank : 39)
Query Neighborhood Hits	298	Target Neighborhood Hits	236	Shared Neighborhood Hits	104
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LAMA3_HUMAN
θ value	0.0736092 (rank : 121)	NC score	0.185003 (rank : 114)
Query Neighborhood Hits	298	Target Neighborhood Hits	760	Shared Neighborhood Hits	143
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MBTP1_HUMAN
θ value	0.0736092 (rank : 122)	NC score	0.095483 (rank : 324)
Query Neighborhood Hits	298	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

NOTC4_HUMAN
θ value	0.0736092 (rank : 123)	NC score	0.189691 (rank : 107)
Query Neighborhood Hits	298	Target Neighborhood Hits	905	Shared Neighborhood Hits	164
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TNR16_MOUSE
θ value	0.0736092 (rank : 124)	NC score	0.158111 (rank : 162)
Query Neighborhood Hits	298	Target Neighborhood Hits	178	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

C1QR1_HUMAN
θ value	0.0961366 (rank : 125)	NC score	0.171659 (rank : 143)
Query Neighborhood Hits	298	Target Neighborhood Hits	493	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

EGF_HUMAN
θ value	0.0961366 (rank : 126)	NC score	0.140570 (rank : 197)
Query Neighborhood Hits	298	Target Neighborhood Hits	343	Shared Neighborhood Hits	124
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

LAMA4_HUMAN
θ value	0.0961366 (rank : 127)	NC score	0.181632 (rank : 124)
Query Neighborhood Hits	298	Target Neighborhood Hits	708	Shared Neighborhood Hits	121
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LYAM2_MOUSE
θ value	0.0961366 (rank : 128)	NC score	0.098134 (rank : 318)
Query Neighborhood Hits	298	Target Neighborhood Hits	420	Shared Neighborhood Hits	126
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

MKS3_MOUSE
θ value	0.0961366 (rank : 129)	NC score	0.095275 (rank : 325)
Query Neighborhood Hits	298	Target Neighborhood Hits	89	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

SLIT3_HUMAN
θ value	0.0961366 (rank : 130)	NC score	0.113113 (rank : 271)
Query Neighborhood Hits	298	Target Neighborhood Hits	682	Shared Neighborhood Hits	137
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

TR10A_HUMAN
θ value	0.0961366 (rank : 131)	NC score	0.084138 (rank : 350)
Query Neighborhood Hits	298	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

ZFY_HUMAN
θ value	0.0961366 (rank : 132)	NC score	0.022972 (rank : 462)
Query Neighborhood Hits	298	Target Neighborhood Hits	752	Shared Neighborhood Hits	47
SwissProt Accessions	P08048, Q14021, Q15558, Q96TF3	Gene names	ZFY
Domain Architecture
Description	Zinc finger Y-chromosomal protein.

EGFL9_MOUSE
θ value	0.125558 (rank : 133)	NC score	0.181722 (rank : 123)
Query Neighborhood Hits	298	Target Neighborhood Hits	379	Shared Neighborhood Hits	135
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

NOTC2_MOUSE
θ value	0.125558 (rank : 134)	NC score	0.186929 (rank : 110)
Query Neighborhood Hits	298	Target Neighborhood Hits	1069	Shared Neighborhood Hits	153
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

VWF_HUMAN
θ value	0.125558 (rank : 135)	NC score	0.155318 (rank : 168)
Query Neighborhood Hits	298	Target Neighborhood Hits	396	Shared Neighborhood Hits	139
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ZFX_MOUSE
θ value	0.125558 (rank : 136)	NC score	0.022521 (rank : 464)
Query Neighborhood Hits	298	Target Neighborhood Hits	748	Shared Neighborhood Hits	46
SwissProt Accessions	P17012, P17011	Gene names	Zfx
Domain Architecture
Description	Zinc finger X-chromosomal protein.

CI094_HUMAN
θ value	0.163984 (rank : 137)	NC score	0.039191 (rank : 451)
Query Neighborhood Hits	298	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

DLL4_HUMAN
θ value	0.163984 (rank : 138)	NC score	0.195901 (rank : 96)
Query Neighborhood Hits	298	Target Neighborhood Hits	435	Shared Neighborhood Hits	151
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

FHL3_HUMAN
θ value	0.163984 (rank : 139)	NC score	0.036415 (rank : 455)
Query Neighborhood Hits	298	Target Neighborhood Hits	354	Shared Neighborhood Hits	44
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

KR106_HUMAN
θ value	0.163984 (rank : 140)	NC score	0.197173 (rank : 93)
Query Neighborhood Hits	298	Target Neighborhood Hits	347	Shared Neighborhood Hits	137
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KRA51_HUMAN
θ value	0.163984 (rank : 141)	NC score	0.284240 (rank : 30)
Query Neighborhood Hits	298	Target Neighborhood Hits	288	Shared Neighborhood Hits	119
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LTBP4_MOUSE
θ value	0.163984 (rank : 142)	NC score	0.208241 (rank : 79)
Query Neighborhood Hits	298	Target Neighborhood Hits	607	Shared Neighborhood Hits	161
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TR11B_HUMAN
θ value	0.163984 (rank : 143)	NC score	0.094760 (rank : 326)
Query Neighborhood Hits	298	Target Neighborhood Hits	92	Shared Neighborhood Hits	54
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TRIM8_HUMAN
θ value	0.163984 (rank : 144)	NC score	0.015314 (rank : 509)
Query Neighborhood Hits	298	Target Neighborhood Hits	650	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ZFX_HUMAN
θ value	0.163984 (rank : 145)	NC score	0.022421 (rank : 465)
Query Neighborhood Hits	298	Target Neighborhood Hits	751	Shared Neighborhood Hits	46
SwissProt Accessions	P17010, O43668, Q8WYJ8	Gene names	ZFX
Domain Architecture
Description	Zinc finger X-chromosomal protein.

DGKG_HUMAN
θ value	0.21417 (rank : 146)	NC score	0.015976 (rank : 503)
Query Neighborhood Hits	298	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

MBTP1_MOUSE
θ value	0.21417 (rank : 147)	NC score	0.089969 (rank : 334)
Query Neighborhood Hits	298	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTZ2, Q6PG67	Gene names	Mbtps1, S1p, Ski1
Domain Architecture
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin isozyme 1) (SKI-1) (Sterol-regulated luminal protease).

NOTC2_HUMAN
θ value	0.21417 (rank : 148)	NC score	0.186060 (rank : 111)
Query Neighborhood Hits	298	Target Neighborhood Hits	1113	Shared Neighborhood Hits	161
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ZFA_MOUSE
θ value	0.21417 (rank : 149)	NC score	0.022220 (rank : 466)
Query Neighborhood Hits	298	Target Neighborhood Hits	746	Shared Neighborhood Hits	45
SwissProt Accessions	P23607	Gene names	Zfa
Domain Architecture
Description	Zinc finger autosomal protein.

ADA28_HUMAN
θ value	0.279714 (rank : 150)	NC score	0.032772 (rank : 457)
Query Neighborhood Hits	298	Target Neighborhood Hits	244	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

DGKG_MOUSE
θ value	0.279714 (rank : 151)	NC score	0.016157 (rank : 501)
Query Neighborhood Hits	298	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

FBLN1_MOUSE
θ value	0.279714 (rank : 152)	NC score	0.180410 (rank : 127)
Query Neighborhood Hits	298	Target Neighborhood Hits	329	Shared Neighborhood Hits	134
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	0.279714 (rank : 153)	NC score	0.189187 (rank : 108)
Query Neighborhood Hits	298	Target Neighborhood Hits	392	Shared Neighborhood Hits	130
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

ZN133_HUMAN
θ value	0.279714 (rank : 154)	NC score	0.017114 (rank : 491)
Query Neighborhood Hits	298	Target Neighborhood Hits	784	Shared Neighborhood Hits	52
SwissProt Accessions	P52736, Q9BUV2, Q9H443	Gene names	ZNF133
Domain Architecture
Description	Zinc finger protein 133.

ADA17_HUMAN
θ value	0.365318 (rank : 155)	NC score	0.056533 (rank : 428)
Query Neighborhood Hits	298	Target Neighborhood Hits	223	Shared Neighborhood Hits	76
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

C1QR1_MOUSE
θ value	0.365318 (rank : 156)	NC score	0.161969 (rank : 159)
Query Neighborhood Hits	298	Target Neighborhood Hits	342	Shared Neighborhood Hits	125
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LYAM1_MOUSE
θ value	0.365318 (rank : 157)	NC score	0.073733 (rank : 382)
Query Neighborhood Hits	298	Target Neighborhood Hits	332	Shared Neighborhood Hits	98
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

NELL2_MOUSE
θ value	0.365318 (rank : 158)	NC score	0.208742 (rank : 77)
Query Neighborhood Hits	298	Target Neighborhood Hits	436	Shared Neighborhood Hits	145
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

TNR21_HUMAN
θ value	0.365318 (rank : 159)	NC score	0.080951 (rank : 360)
Query Neighborhood Hits	298	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TR13B_MOUSE
θ value	0.365318 (rank : 160)	NC score	0.058257 (rank : 423)
Query Neighborhood Hits	298	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ET35, Q9DBZ3	Gene names	Tnfrsf13b, Taci
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor).

ATS16_MOUSE
θ value	0.47712 (rank : 161)	NC score	0.036550 (rank : 454)
Query Neighborhood Hits	298	Target Neighborhood Hits	179	Shared Neighborhood Hits	33
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

FBN2_MOUSE
θ value	0.47712 (rank : 162)	NC score	0.209191 (rank : 75)
Query Neighborhood Hits	298	Target Neighborhood Hits	549	Shared Neighborhood Hits	177
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

JAG2_MOUSE
θ value	0.47712 (rank : 163)	NC score	0.199891 (rank : 90)
Query Neighborhood Hits	298	Target Neighborhood Hits	504	Shared Neighborhood Hits	147
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LAMB3_MOUSE
θ value	0.47712 (rank : 164)	NC score	0.214752 (rank : 64)
Query Neighborhood Hits	298	Target Neighborhood Hits	444	Shared Neighborhood Hits	133
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC2_MOUSE
θ value	0.47712 (rank : 165)	NC score	0.217194 (rank : 62)
Query Neighborhood Hits	298	Target Neighborhood Hits	614	Shared Neighborhood Hits	170
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

TRIM8_MOUSE
θ value	0.47712 (rank : 166)	NC score	0.014681 (rank : 513)
Query Neighborhood Hits	298	Target Neighborhood Hits	674	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ZN227_HUMAN
θ value	0.47712 (rank : 167)	NC score	0.019846 (rank : 477)
Query Neighborhood Hits	298	Target Neighborhood Hits	781	Shared Neighborhood Hits	61
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

ZN236_HUMAN
θ value	0.47712 (rank : 168)	NC score	0.016289 (rank : 499)
Query Neighborhood Hits	298	Target Neighborhood Hits	844	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

ZNF44_HUMAN
θ value	0.47712 (rank : 169)	NC score	0.019754 (rank : 478)
Query Neighborhood Hits	298	Target Neighborhood Hits	757	Shared Neighborhood Hits	54
SwissProt Accessions	P15621, P17018, Q9ULZ7	Gene names	ZNF44, KOX7
Domain Architecture
Description	Zinc finger protein 44 (Zinc finger protein KOX7) (Gonadotropin- inducible transcription repressor 2) (GIOT-2).

KRA53_HUMAN
θ value	0.62314 (rank : 170)	NC score	0.263024 (rank : 36)
Query Neighborhood Hits	298	Target Neighborhood Hits	331	Shared Neighborhood Hits	136
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

LAMA3_MOUSE
θ value	0.62314 (rank : 171)	NC score	0.200557 (rank : 89)
Query Neighborhood Hits	298	Target Neighborhood Hits	859	Shared Neighborhood Hits	169
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

MYRIP_MOUSE
θ value	0.62314 (rank : 172)	NC score	0.021519 (rank : 471)
Query Neighborhood Hits	298	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

NAGPA_HUMAN
θ value	0.62314 (rank : 173)	NC score	0.184809 (rank : 116)
Query Neighborhood Hits	298	Target Neighborhood Hits	282	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

TRI32_HUMAN
θ value	0.62314 (rank : 174)	NC score	0.018249 (rank : 485)
Query Neighborhood Hits	298	Target Neighborhood Hits	264	Shared Neighborhood Hits	12
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

ZN343_HUMAN
θ value	0.62314 (rank : 175)	NC score	0.016653 (rank : 495)
Query Neighborhood Hits	298	Target Neighborhood Hits	768	Shared Neighborhood Hits	52
SwissProt Accessions	Q6P1L6, Q5JXU8, Q5JXU9, Q8N8F2, Q96EX8, Q96NA5, Q9BQB0	Gene names	ZNF343
Domain Architecture	No domain graphic available
Description	Zinc finger protein 343.

ZN700_HUMAN
θ value	0.62314 (rank : 176)	NC score	0.018176 (rank : 486)
Query Neighborhood Hits	298	Target Neighborhood Hits	772	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H0M5	Gene names	ZNF700
Domain Architecture	No domain graphic available
Description	Zinc finger protein 700.

ZNF45_HUMAN
θ value	0.62314 (rank : 177)	NC score	0.021866 (rank : 467)
Query Neighborhood Hits	298	Target Neighborhood Hits	773	Shared Neighborhood Hits	68
SwissProt Accessions	Q02386, P78472, Q9P1U9	Gene names	ZNF45
Domain Architecture
Description	Zinc finger protein 45 (BRC1744).

LAMC2_HUMAN
θ value	0.813845 (rank : 178)	NC score	0.204122 (rank : 85)
Query Neighborhood Hits	298	Target Neighborhood Hits	715	Shared Neighborhood Hits	157
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LRP2_HUMAN
θ value	0.813845 (rank : 179)	NC score	0.146415 (rank : 187)
Query Neighborhood Hits	298	Target Neighborhood Hits	573	Shared Neighborhood Hits	159
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

PCSK9_HUMAN
θ value	0.813845 (rank : 180)	NC score	0.060343 (rank : 420)
Query Neighborhood Hits	298	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBP7, Q5PSM5	Gene names	PCSK9, NARC1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

TNR1A_HUMAN
θ value	0.813845 (rank : 181)	NC score	0.102111 (rank : 308)
Query Neighborhood Hits	298	Target Neighborhood Hits	121	Shared Neighborhood Hits	45
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR5_HUMAN
θ value	0.813845 (rank : 182)	NC score	0.086361 (rank : 342)
Query Neighborhood Hits	298	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

ZN197_HUMAN
θ value	0.813845 (rank : 183)	NC score	0.016353 (rank : 498)
Query Neighborhood Hits	298	Target Neighborhood Hits	788	Shared Neighborhood Hits	51
SwissProt Accessions	O14709	Gene names	ZNF197, ZNF166
Domain Architecture
Description	Zinc finger protein 197 (ZnF20).

ZN441_HUMAN
θ value	0.813845 (rank : 184)	NC score	0.021106 (rank : 474)
Query Neighborhood Hits	298	Target Neighborhood Hits	754	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N8Z8	Gene names	ZNF441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 441.

ZNFX1_MOUSE
θ value	0.813845 (rank : 185)	NC score	0.106037 (rank : 296)
Query Neighborhood Hits	298	Target Neighborhood Hits	407	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ATS16_HUMAN
θ value	1.06291 (rank : 186)	NC score	0.035440 (rank : 456)
Query Neighborhood Hits	298	Target Neighborhood Hits	208	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

HKR1_HUMAN
θ value	1.06291 (rank : 187)	NC score	0.015971 (rank : 504)
Query Neighborhood Hits	298	Target Neighborhood Hits	759	Shared Neighborhood Hits	47
SwissProt Accessions	P10072, Q9BSW9, Q9UM09	Gene names	HKR1
Domain Architecture
Description	Krueppel-related zinc finger protein 1 (Protein HKR1).

KRA58_HUMAN
θ value	1.06291 (rank : 188)	NC score	0.246348 (rank : 41)
Query Neighborhood Hits	298	Target Neighborhood Hits	324	Shared Neighborhood Hits	127
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMA4_MOUSE
θ value	1.06291 (rank : 189)	NC score	0.190241 (rank : 104)
Query Neighborhood Hits	298	Target Neighborhood Hits	584	Shared Neighborhood Hits	123
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LRP1B_HUMAN
θ value	1.06291 (rank : 190)	NC score	0.149013 (rank : 180)
Query Neighborhood Hits	298	Target Neighborhood Hits	602	Shared Neighborhood Hits	160
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TNR3_HUMAN
θ value	1.06291 (rank : 191)	NC score	0.102150 (rank : 307)
Query Neighborhood Hits	298	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TRI32_MOUSE
θ value	1.06291 (rank : 192)	NC score	0.017181 (rank : 490)
Query Neighborhood Hits	298	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

VEGFC_HUMAN
θ value	1.06291 (rank : 193)	NC score	0.077665 (rank : 374)
Query Neighborhood Hits	298	Target Neighborhood Hits	128	Shared Neighborhood Hits	63
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ZN575_MOUSE
θ value	1.06291 (rank : 194)	NC score	0.015453 (rank : 508)
Query Neighborhood Hits	298	Target Neighborhood Hits	715	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TXZ1	Gene names	Znf575, Zfp575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

ZN709_HUMAN
θ value	1.06291 (rank : 195)	NC score	0.018915 (rank : 481)
Query Neighborhood Hits	298	Target Neighborhood Hits	746	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N972	Gene names	ZNF709
Domain Architecture	No domain graphic available
Description	Zinc finger protein 709.

ZN711_HUMAN
θ value	1.06291 (rank : 196)	NC score	0.021513 (rank : 472)
Query Neighborhood Hits	298	Target Neighborhood Hits	751	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

ZNF22_HUMAN
θ value	1.06291 (rank : 197)	NC score	0.013983 (rank : 516)
Query Neighborhood Hits	298	Target Neighborhood Hits	723	Shared Neighborhood Hits	45
SwissProt Accessions	P17026, Q96FM4	Gene names	ZNF22, KOX15, KROX26
Domain Architecture	No domain graphic available
Description	Zinc finger protein 22 (Zinc finger protein KOX15) (Krox-26 protein).

ASM3A_HUMAN
θ value	1.38821 (rank : 198)	NC score	0.015839 (rank : 505)
Query Neighborhood Hits	298	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q92484, Q8WV13	Gene names	SMPDL3A, ASML3A
Domain Architecture	No domain graphic available
Description	Acid sphingomyelinase-like phosphodiesterase 3a precursor (EC 3.1.4.-) (ASM-like phosphodiesterase 3a).

EPHA1_MOUSE
θ value	1.38821 (rank : 199)	NC score	0.045456 (rank : 446)
Query Neighborhood Hits	298	Target Neighborhood Hits	958	Shared Neighborhood Hits	74
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

KRA13_HUMAN
θ value	1.38821 (rank : 200)	NC score	0.136738 (rank : 203)
Query Neighborhood Hits	298	Target Neighborhood Hits	144	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

PHF7_HUMAN
θ value	1.38821 (rank : 201)	NC score	0.030766 (rank : 459)
Query Neighborhood Hits	298	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

RECK_MOUSE
θ value	1.38821 (rank : 202)	NC score	0.069745 (rank : 391)
Query Neighborhood Hits	298	Target Neighborhood Hits	158	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TNR8_HUMAN
θ value	1.38821 (rank : 203)	NC score	0.095649 (rank : 322)
Query Neighborhood Hits	298	Target Neighborhood Hits	198	Shared Neighborhood Hits	68
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TRBM_MOUSE
θ value	1.38821 (rank : 204)	NC score	0.174418 (rank : 140)
Query Neighborhood Hits	298	Target Neighborhood Hits	361	Shared Neighborhood Hits	134
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ADA19_MOUSE
θ value	1.81305 (rank : 205)	NC score	0.052760 (rank : 436)
Query Neighborhood Hits	298	Target Neighborhood Hits	315	Shared Neighborhood Hits	106
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

CRUM2_HUMAN
θ value	1.81305 (rank : 206)	NC score	0.180973 (rank : 126)
Query Neighborhood Hits	298	Target Neighborhood Hits	453	Shared Neighborhood Hits	142
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

HMCN1_HUMAN
θ value	1.81305 (rank : 207)	NC score	0.115187 (rank : 265)
Query Neighborhood Hits	298	Target Neighborhood Hits	983	Shared Neighborhood Hits	150
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

KRA11_HUMAN
θ value	1.81305 (rank : 208)	NC score	0.132001 (rank : 212)
Query Neighborhood Hits	298	Target Neighborhood Hits	155	Shared Neighborhood Hits	66
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

LRP1B_MOUSE
θ value	1.81305 (rank : 209)	NC score	0.146941 (rank : 185)
Query Neighborhood Hits	298	Target Neighborhood Hits	606	Shared Neighborhood Hits	155
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LTBP2_HUMAN
θ value	1.81305 (rank : 210)	NC score	0.204782 (rank : 82)
Query Neighborhood Hits	298	Target Neighborhood Hits	552	Shared Neighborhood Hits	157
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MYRIP_HUMAN
θ value	1.81305 (rank : 211)	NC score	0.019330 (rank : 480)
Query Neighborhood Hits	298	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

OVOL2_HUMAN
θ value	1.81305 (rank : 212)	NC score	0.015214 (rank : 510)
Query Neighborhood Hits	298	Target Neighborhood Hits	715	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BRP0, Q5T8B4, Q9BX22, Q9HA54, Q9Y4M0	Gene names	OVOL2, ZNF339
Domain Architecture	No domain graphic available
Description	Transcription factor Ovo-like 2 (hOvo2) (Zinc finger protein 339).

SSPO_MOUSE
θ value	1.81305 (rank : 213)	NC score	0.164514 (rank : 157)
Query Neighborhood Hits	298	Target Neighborhood Hits	800	Shared Neighborhood Hits	187
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ZFP28_HUMAN
θ value	1.81305 (rank : 214)	NC score	0.017025 (rank : 492)
Query Neighborhood Hits	298	Target Neighborhood Hits	843	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

ZFY2_MOUSE
θ value	1.81305 (rank : 215)	NC score	0.021831 (rank : 468)
Query Neighborhood Hits	298	Target Neighborhood Hits	795	Shared Neighborhood Hits	47
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.

ZN491_HUMAN
θ value	1.81305 (rank : 216)	NC score	0.016428 (rank : 497)
Query Neighborhood Hits	298	Target Neighborhood Hits	734	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N8L2, Q8NAT8	Gene names	ZNF491
Domain Architecture	No domain graphic available
Description	Zinc finger protein 491.

ZN570_HUMAN
θ value	1.81305 (rank : 217)	NC score	0.015051 (rank : 511)
Query Neighborhood Hits	298	Target Neighborhood Hits	758	Shared Neighborhood Hits	49
SwissProt Accessions	Q96NI8	Gene names	ZNF570
Domain Architecture	No domain graphic available
Description	Zinc finger protein 570.

ITB2_HUMAN
θ value	2.36792 (rank : 218)	NC score	0.117410 (rank : 260)
Query Neighborhood Hits	298	Target Neighborhood Hits	282	Shared Neighborhood Hits	129
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

JAG2_HUMAN
θ value	2.36792 (rank : 219)	NC score	0.201962 (rank : 88)
Query Neighborhood Hits	298	Target Neighborhood Hits	491	Shared Neighborhood Hits	148
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

KALM_HUMAN
θ value	2.36792 (rank : 220)	NC score	0.027132 (rank : 460)
Query Neighborhood Hits	298	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

KRA47_HUMAN
θ value	2.36792 (rank : 221)	NC score	0.156196 (rank : 164)
Query Neighborhood Hits	298	Target Neighborhood Hits	204	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

LRP1_HUMAN
θ value	2.36792 (rank : 222)	NC score	0.154577 (rank : 171)
Query Neighborhood Hits	298	Target Neighborhood Hits	617	Shared Neighborhood Hits	166
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MATN2_MOUSE
θ value	2.36792 (rank : 223)	NC score	0.172743 (rank : 142)
Query Neighborhood Hits	298	Target Neighborhood Hits	356	Shared Neighborhood Hits	131
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

NAGPA_MOUSE
θ value	2.36792 (rank : 224)	NC score	0.175397 (rank : 138)
Query Neighborhood Hits	298	Target Neighborhood Hits	308	Shared Neighborhood Hits	128
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

POLI_MOUSE
θ value	2.36792 (rank : 225)	NC score	0.010606 (rank : 519)
Query Neighborhood Hits	298	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

RNF37_MOUSE
θ value	2.36792 (rank : 226)	NC score	0.020939 (rank : 476)
Query Neighborhood Hits	298	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

TNR23_MOUSE
θ value	2.36792 (rank : 227)	NC score	0.127241 (rank : 225)
Query Neighborhood Hits	298	Target Neighborhood Hits	114	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TR11B_MOUSE
θ value	2.36792 (rank : 228)	NC score	0.078389 (rank : 371)
Query Neighborhood Hits	298	Target Neighborhood Hits	95	Shared Neighborhood Hits	53
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

ZAN_HUMAN
θ value	2.36792 (rank : 229)	NC score	0.119556 (rank : 250)
Query Neighborhood Hits	298	Target Neighborhood Hits	679	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ZFY1_MOUSE
θ value	2.36792 (rank : 230)	NC score	0.021583 (rank : 469)
Query Neighborhood Hits	298	Target Neighborhood Hits	790	Shared Neighborhood Hits	45
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

CORIN_MOUSE
θ value	3.0926 (rank : 231)	NC score	0.036680 (rank : 453)
Query Neighborhood Hits	298	Target Neighborhood Hits	451	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

LAMB3_HUMAN
θ value	3.0926 (rank : 232)	NC score	0.207465 (rank : 80)
Query Neighborhood Hits	298	Target Neighborhood Hits	461	Shared Neighborhood Hits	127
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

MKS3_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.082073 (rank : 355)
Query Neighborhood Hits	298	Target Neighborhood Hits	79	Shared Neighborhood Hits	56
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

NET2_HUMAN
θ value	3.0926 (rank : 234)	NC score	0.171493 (rank : 144)
Query Neighborhood Hits	298	Target Neighborhood Hits	194	Shared Neighborhood Hits	102
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NID2_MOUSE
θ value	3.0926 (rank : 235)	NC score	0.149919 (rank : 178)
Query Neighborhood Hits	298	Target Neighborhood Hits	338	Shared Neighborhood Hits	117
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC4_MOUSE
θ value	3.0926 (rank : 236)	NC score	0.184981 (rank : 115)
Query Neighborhood Hits	298	Target Neighborhood Hits	872	Shared Neighborhood Hits	160
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOV_HUMAN
θ value	3.0926 (rank : 237)	NC score	0.040938 (rank : 449)
Query Neighborhood Hits	298	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

TIE2_HUMAN
θ value	3.0926 (rank : 238)	NC score	0.087249 (rank : 339)
Query Neighborhood Hits	298	Target Neighborhood Hits	1192	Shared Neighborhood Hits	136
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIF1G_HUMAN
θ value	3.0926 (rank : 239)	NC score	0.009788 (rank : 520)
Query Neighborhood Hits	298	Target Neighborhood Hits	410	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TNR11_HUMAN
θ value	3.0926 (rank : 240)	NC score	0.084490 (rank : 349)
Query Neighborhood Hits	298	Target Neighborhood Hits	135	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR4_HUMAN
θ value	3.0926 (rank : 241)	NC score	0.099811 (rank : 313)
Query Neighborhood Hits	298	Target Neighborhood Hits	152	Shared Neighborhood Hits	71
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR9_MOUSE
θ value	3.0926 (rank : 242)	NC score	0.123615 (rank : 239)
Query Neighborhood Hits	298	Target Neighborhood Hits	137	Shared Neighborhood Hits	72
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

ZN189_HUMAN
θ value	3.0926 (rank : 243)	NC score	0.018478 (rank : 484)
Query Neighborhood Hits	298	Target Neighborhood Hits	754	Shared Neighborhood Hits	51
SwissProt Accessions	O75820, O75802, Q5T7D9, Q9UBL4, Q9UPE9, Q9UPF0, Q9UPF1	Gene names	ZNF189
Domain Architecture
Description	Zinc finger protein 189.

ZN226_HUMAN
θ value	3.0926 (rank : 244)	NC score	0.017983 (rank : 487)
Query Neighborhood Hits	298	Target Neighborhood Hits	770	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NYT6, Q96TE6, Q9NS44	Gene names	ZNF226
Domain Architecture
Description	Zinc finger protein 226.

ZN228_HUMAN
θ value	3.0926 (rank : 245)	NC score	0.017766 (rank : 489)
Query Neighborhood Hits	298	Target Neighborhood Hits	775	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UJU3, Q9HCA7	Gene names	ZNF228
Domain Architecture
Description	Zinc finger protein 228.

ZN239_HUMAN
θ value	3.0926 (rank : 246)	NC score	0.015597 (rank : 507)
Query Neighborhood Hits	298	Target Neighborhood Hits	746	Shared Neighborhood Hits	53
SwissProt Accessions	Q16600, Q5T1G9, Q8TAS5	Gene names	ZNF239, HOK2, MOK2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 239 (Zinc finger protein MOK-2) (HOK-2).

ZN285_HUMAN
θ value	3.0926 (rank : 247)	NC score	0.016718 (rank : 494)
Query Neighborhood Hits	298	Target Neighborhood Hits	728	Shared Neighborhood Hits	54
SwissProt Accessions	Q96NJ3	Gene names	ZNF285
Domain Architecture	No domain graphic available
Description	Zinc finger protein 285.

ZN615_HUMAN
θ value	3.0926 (rank : 248)	NC score	0.017773 (rank : 488)
Query Neighborhood Hits	298	Target Neighborhood Hits	775	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N8J6	Gene names	ZNF615
Domain Architecture	No domain graphic available
Description	Zinc finger protein 615.

ASM3A_MOUSE
θ value	4.03905 (rank : 249)	NC score	0.013364 (rank : 518)
Query Neighborhood Hits	298	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P70158	Gene names	Smpdl3a, Asml3a
Domain Architecture
Description	Acid sphingomyelinase-like phosphodiesterase 3a precursor (EC 3.1.4.-) (ASM-like phosphodiesterase 3a).

CNBP_MOUSE
θ value	4.03905 (rank : 250)	NC score	0.018679 (rank : 483)
Query Neighborhood Hits	298	Target Neighborhood Hits	215	Shared Neighborhood Hits	24
SwissProt Accessions	P53996, Q80Y06, Q8BP23	Gene names	Cnbp, Cnbp1, Znf9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

LHX2_HUMAN
θ value	4.03905 (rank : 251)	NC score	0.002066 (rank : 530)
Query Neighborhood Hits	298	Target Neighborhood Hits	432	Shared Neighborhood Hits	6
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

LHX2_MOUSE
θ value	4.03905 (rank : 252)	NC score	0.002087 (rank : 529)
Query Neighborhood Hits	298	Target Neighborhood Hits	431	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0S2	Gene names	Lhx2
Domain Architecture
Description	LIM/homeobox protein Lhx2.

MIZF_MOUSE
θ value	4.03905 (rank : 253)	NC score	0.016118 (rank : 502)
Query Neighborhood Hits	298	Target Neighborhood Hits	726	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K1K9, Q8BWY0	Gene names	Mizf
Domain Architecture	No domain graphic available
Description	MBD2-interacting zinc finger protein (Methyl-CpG-binding protein 2- interacting zinc finger protein).

MLL4_HUMAN
θ value	4.03905 (rank : 254)	NC score	0.008581 (rank : 525)
Query Neighborhood Hits	298	Target Neighborhood Hits	722	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TAF6L_MOUSE
θ value	4.03905 (rank : 255)	NC score	0.008642 (rank : 524)
Query Neighborhood Hits	298	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

TIF1G_MOUSE
θ value	4.03905 (rank : 256)	NC score	0.009192 (rank : 522)
Query Neighborhood Hits	298	Target Neighborhood Hits	498	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

ZFP28_MOUSE
θ value	4.03905 (rank : 257)	NC score	0.018852 (rank : 482)
Query Neighborhood Hits	298	Target Neighborhood Hits	782	Shared Neighborhood Hits	54
SwissProt Accessions	P10078, Q61776, Q8BT11, Q8C836	Gene names	Zfp28, Mkr5, Zfp-28
Domain Architecture
Description	Zinc finger protein 28 (Zfp-28) (Protein mKR5).

ZN239_MOUSE
θ value	4.03905 (rank : 258)	NC score	0.014779 (rank : 512)
Query Neighborhood Hits	298	Target Neighborhood Hits	723	Shared Neighborhood Hits	47
SwissProt Accessions	P24399	Gene names	Znf239, Mok-2, Mok2, Zfp239
Domain Architecture	No domain graphic available
Description	Zinc finger protein 239 (Zfp-239) (Zinc finger protein MOK-2).

ADA17_MOUSE
θ value	5.27518 (rank : 259)	NC score	0.038617 (rank : 452)
Query Neighborhood Hits	298	Target Neighborhood Hits	201	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

CUBN_MOUSE
θ value	5.27518 (rank : 260)	NC score	0.153083 (rank : 174)
Query Neighborhood Hits	298	Target Neighborhood Hits	477	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DLL1_MOUSE
θ value	5.27518 (rank : 261)	NC score	0.193909 (rank : 98)
Query Neighborhood Hits	298	Target Neighborhood Hits	456	Shared Neighborhood Hits	151
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

KRA92_HUMAN
θ value	5.27518 (rank : 262)	NC score	0.150903 (rank : 176)
Query Neighborhood Hits	298	Target Neighborhood Hits	198	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LTBP3_HUMAN
θ value	5.27518 (rank : 263)	NC score	0.183907 (rank : 121)
Query Neighborhood Hits	298	Target Neighborhood Hits	502	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	5.27518 (rank : 264)	NC score	0.187337 (rank : 109)
Query Neighborhood Hits	298	Target Neighborhood Hits	475	Shared Neighborhood Hits	146
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

PRDM5_HUMAN
θ value	5.27518 (rank : 265)	NC score	0.015753 (rank : 506)
Query Neighborhood Hits	298	Target Neighborhood Hits	790	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NQX1	Gene names	PRDM5, PFM2
Domain Architecture
Description	PR domain zinc finger protein 5 (PR domain-containing protein 5).

SPRE1_MOUSE
θ value	5.27518 (rank : 266)	NC score	0.008787 (rank : 523)
Query Neighborhood Hits	298	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q924S8, Q6PET8	Gene names	Spred1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

TIE1_MOUSE
θ value	5.27518 (rank : 267)	NC score	0.096648 (rank : 320)
Query Neighborhood Hits	298	Target Neighborhood Hits	1266	Shared Neighborhood Hits	144
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TNR14_HUMAN
θ value	5.27518 (rank : 268)	NC score	0.127557 (rank : 222)
Query Neighborhood Hits	298	Target Neighborhood Hits	149	Shared Neighborhood Hits	90
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR4_MOUSE
θ value	5.27518 (rank : 269)	NC score	0.113132 (rank : 270)
Query Neighborhood Hits	298	Target Neighborhood Hits	137	Shared Neighborhood Hits	77
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TR10B_HUMAN
θ value	5.27518 (rank : 270)	NC score	0.068865 (rank : 394)
Query Neighborhood Hits	298	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

ZN694_HUMAN
θ value	5.27518 (rank : 271)	NC score	0.014238 (rank : 515)
Query Neighborhood Hits	298	Target Neighborhood Hits	764	Shared Neighborhood Hits	49
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.

ZNFX1_HUMAN
θ value	5.27518 (rank : 272)	NC score	0.112551 (rank : 275)
Query Neighborhood Hits	298	Target Neighborhood Hits	308	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ATRN_MOUSE
θ value	6.88961 (rank : 273)	NC score	0.158043 (rank : 163)
Query Neighborhood Hits	298	Target Neighborhood Hits	519	Shared Neighborhood Hits	137
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CO2_HUMAN
θ value	6.88961 (rank : 274)	NC score	0.002337 (rank : 528)
Query Neighborhood Hits	298	Target Neighborhood Hits	258	Shared Neighborhood Hits	8
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

EDAR_HUMAN
θ value	6.88961 (rank : 275)	NC score	0.030859 (rank : 458)
Query Neighborhood Hits	298	Target Neighborhood Hits	84	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

FAM5B_HUMAN
θ value	6.88961 (rank : 276)	NC score	0.019490 (rank : 479)
Query Neighborhood Hits	298	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

FAM5B_MOUSE
θ value	6.88961 (rank : 277)	NC score	0.021524 (rank : 470)
Query Neighborhood Hits	298	Target Neighborhood Hits	51	Shared Neighborhood Hits	21
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

FATH_HUMAN
θ value	6.88961 (rank : 278)	NC score	0.076679 (rank : 376)
Query Neighborhood Hits	298	Target Neighborhood Hits	570	Shared Neighborhood Hits	129
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FGD1_MOUSE
θ value	6.88961 (rank : 279)	NC score	0.000351 (rank : 533)
Query Neighborhood Hits	298	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

HIOM_HUMAN
θ value	6.88961 (rank : 280)	NC score	0.009754 (rank : 521)
Query Neighborhood Hits	298	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	P46597, Q16598, Q5JQ72, Q5JQ73	Gene names	ASMT
Domain Architecture
Description	Hydroxyindole O-methyltransferase (EC 2.1.1.4) (HIOMT) (Acetylserotonin O-methyltransferase) (ASMT).

KRA54_HUMAN
θ value	6.88961 (rank : 281)	NC score	0.262262 (rank : 37)
Query Neighborhood Hits	298	Target Neighborhood Hits	270	Shared Neighborhood Hits	115
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

TRI27_MOUSE
θ value	6.88961 (rank : 282)	NC score	0.001818 (rank : 531)
Query Neighborhood Hits	298	Target Neighborhood Hits	261	Shared Neighborhood Hits	9
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

WDHD1_HUMAN
θ value	6.88961 (rank : 283)	NC score	0.000608 (rank : 532)
Query Neighborhood Hits	298	Target Neighborhood Hits	342	Shared Neighborhood Hits	3
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

ZN442_HUMAN
θ value	6.88961 (rank : 284)	NC score	0.016207 (rank : 500)
Query Neighborhood Hits	298	Target Neighborhood Hits	744	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H7R0	Gene names	ZNF442
Domain Architecture
Description	Zinc finger protein 442.

2ACA_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.005951 (rank : 526)
Query Neighborhood Hits	298	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

FA76B_HUMAN
θ value	8.99809 (rank : 286)	NC score	0.023284 (rank : 461)
Query Neighborhood Hits	298	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FA76B_MOUSE
θ value	8.99809 (rank : 287)	NC score	0.039769 (rank : 450)
Query Neighborhood Hits	298	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FOXL1_MOUSE
θ value	8.99809 (rank : 288)	NC score	-0.000641 (rank : 534)
Query Neighborhood Hits	298	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

LAP4_MOUSE
θ value	8.99809 (rank : 289)	NC score	-0.003557 (rank : 535)
Query Neighborhood Hits	298	Target Neighborhood Hits	590	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

MUC5B_HUMAN
θ value	8.99809 (rank : 290)	NC score	0.130588 (rank : 215)
Query Neighborhood Hits	298	Target Neighborhood Hits	1020	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYNN_HUMAN
θ value	8.99809 (rank : 291)	NC score	0.013779 (rank : 517)
Query Neighborhood Hits	298	Target Neighborhood Hits	826	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NPC7, Q6QHA6, Q6QHA7, Q6R3G1, Q6R3G2, Q6R4A0, Q7Z716, Q7Z717, Q86Z11, Q86Z12, Q9NS01, Q9UIW8	Gene names	MYNN, OSZF, ZBTB31
Domain Architecture	No domain graphic available
Description	Myoneurin (Zinc finger and BTB domain-containing protein 31).

NET2_MOUSE
θ value	8.99809 (rank : 292)	NC score	0.168661 (rank : 148)
Query Neighborhood Hits	298	Target Neighborhood Hits	193	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

PAQR6_HUMAN
θ value	8.99809 (rank : 293)	NC score	0.003145 (rank : 527)
Query Neighborhood Hits	298	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q6TCH4, Q6PDU0, Q7Z4Q7, Q7Z4Q9, Q8N121, Q8N3M2, Q9H621	Gene names	PAQR6
Domain Architecture	No domain graphic available
Description	Progestin and adipoQ receptor family member 6 (Progestin and adipoQ receptor family member VI).

TNR25_HUMAN
θ value	8.99809 (rank : 294)	NC score	0.155910 (rank : 166)
Query Neighborhood Hits	298	Target Neighborhood Hits	172	Shared Neighborhood Hits	85
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TSP4_HUMAN
θ value	8.99809 (rank : 295)	NC score	0.124609 (rank : 234)
Query Neighborhood Hits	298	Target Neighborhood Hits	277	Shared Neighborhood Hits	112
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

ZN563_HUMAN
θ value	8.99809 (rank : 296)	NC score	0.016477 (rank : 496)
Query Neighborhood Hits	298	Target Neighborhood Hits	754	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TA94, Q8NAT7	Gene names	ZNF563
Domain Architecture	No domain graphic available
Description	Zinc finger protein 563.

ZN569_HUMAN
θ value	8.99809 (rank : 297)	NC score	0.016939 (rank : 493)
Query Neighborhood Hits	298	Target Neighborhood Hits	759	Shared Neighborhood Hits	55
SwissProt Accessions	Q5MCW4, Q15925, Q96MQ2	Gene names	ZNF569
Domain Architecture	No domain graphic available
Description	Zinc finger protein 569.

ZN575_HUMAN
θ value	8.99809 (rank : 298)	NC score	0.014459 (rank : 514)
Query Neighborhood Hits	298	Target Neighborhood Hits	739	Shared Neighborhood Hits	46
SwissProt Accessions	Q86XF7	Gene names	ZNF575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

AGRIN_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.199777 (rank : 91)
Query Neighborhood Hits	298	Target Neighborhood Hits	582	Shared Neighborhood Hits	152
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ATRN_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.148188 (rank : 182)
Query Neighborhood Hits	298	Target Neighborhood Hits	525	Shared Neighborhood Hits	134
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

BMPER_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.133337 (rank : 208)
Query Neighborhood Hits	298	Target Neighborhood Hits	175	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.141043 (rank : 196)
Query Neighborhood Hits	298	Target Neighborhood Hits	194	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CD248_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.118418 (rank : 254)
Query Neighborhood Hits	298	Target Neighborhood Hits	679	Shared Neighborhood Hits	116
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.115560 (rank : 264)
Query Neighborhood Hits	298	Target Neighborhood Hits	578	Shared Neighborhood Hits	107
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.114953 (rank : 266)
Query Neighborhood Hits	298	Target Neighborhood Hits	353	Shared Neighborhood Hits	109
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.089281 (rank : 336)
Query Neighborhood Hits	298	Target Neighborhood Hits	295	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CELR1_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.079662 (rank : 362)
Query Neighborhood Hits	298	Target Neighborhood Hits	613	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.079786 (rank : 361)
Query Neighborhood Hits	298	Target Neighborhood Hits	617	Shared Neighborhood Hits	135
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.083781 (rank : 351)
Query Neighborhood Hits	298	Target Neighborhood Hits	657	Shared Neighborhood Hits	137
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.082592 (rank : 354)
Query Neighborhood Hits	298	Target Neighborhood Hits	680	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.083535 (rank : 352)
Query Neighborhood Hits	298	Target Neighborhood Hits	687	Shared Neighborhood Hits	138
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CFC1_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.077437 (rank : 375)
Query Neighborhood Hits	298	Target Neighborhood Hits	148	Shared Neighborhood Hits	66
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.063288 (rank : 409)
Query Neighborhood Hits	298	Target Neighborhood Hits	125	Shared Neighborhood Hits	60
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CHRD_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.073768 (rank : 381)
Query Neighborhood Hits	298	Target Neighborhood Hits	102	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.072772 (rank : 385)
Query Neighborhood Hits	298	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.135039 (rank : 204)
Query Neighborhood Hits	298	Target Neighborhood Hits	258	Shared Neighborhood Hits	119
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.134061 (rank : 206)
Query Neighborhood Hits	298	Target Neighborhood Hits	290	Shared Neighborhood Hits	129
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRAC1_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.066829 (rank : 399)
Query Neighborhood Hits	298	Target Neighborhood Hits	111	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.067250 (rank : 397)
Query Neighborhood Hits	298	Target Neighborhood Hits	112	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRDL2_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.051783 (rank : 441)
Query Neighborhood Hits	298	Target Neighborhood Hits	99	Shared Neighborhood Hits	26
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.052031 (rank : 439)
Query Neighborhood Hits	298	Target Neighborhood Hits	81	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.184157 (rank : 119)
Query Neighborhood Hits	298	Target Neighborhood Hits	444	Shared Neighborhood Hits	140
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CSPG2_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.078110 (rank : 372)
Query Neighborhood Hits	298	Target Neighborhood Hits	681	Shared Neighborhood Hits	111
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.079491 (rank : 364)
Query Neighborhood Hits	298	Target Neighborhood Hits	711	Shared Neighborhood Hits	111
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.079482 (rank : 365)
Query Neighborhood Hits	298	Target Neighborhood Hits	676	Shared Neighborhood Hits	117
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.081518 (rank : 357)
Query Neighborhood Hits	298	Target Neighborhood Hits	657	Shared Neighborhood Hits	117
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG4_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.059808 (rank : 422)
Query Neighborhood Hits	298	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.057301 (rank : 425)
Query Neighborhood Hits	298	Target Neighborhood Hits	105	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CT127_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.066658 (rank : 400)
Query Neighborhood Hits	298	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CUBN_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.155463 (rank : 167)
Query Neighborhood Hits	298	Target Neighborhood Hits	482	Shared Neighborhood Hits	133
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

DLK_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.178752 (rank : 130)
Query Neighborhood Hits	298	Target Neighborhood Hits	401	Shared Neighborhood Hits	149
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.177467 (rank : 132)
Query Neighborhood Hits	298	Target Neighborhood Hits	374	Shared Neighborhood Hits	137
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.189772 (rank : 106)
Query Neighborhood Hits	298	Target Neighborhood Hits	455	Shared Neighborhood Hits	150
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL3_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.179578 (rank : 128)
Query Neighborhood Hits	298	Target Neighborhood Hits	419	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.175459 (rank : 137)
Query Neighborhood Hits	298	Target Neighborhood Hits	399	Shared Neighborhood Hits	135
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DNER_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.184422 (rank : 118)
Query Neighborhood Hits	298	Target Neighborhood Hits	460	Shared Neighborhood Hits	140
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.178957 (rank : 129)
Query Neighborhood Hits	298	Target Neighborhood Hits	413	Shared Neighborhood Hits	137
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.100722 (rank : 312)
Query Neighborhood Hits	298	Target Neighborhood Hits	292	Shared Neighborhood Hits	110
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.107874 (rank : 292)
Query Neighborhood Hits	298	Target Neighborhood Hits	317	Shared Neighborhood Hits	118
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.131022 (rank : 214)
Query Neighborhood Hits	298	Target Neighborhood Hits	325	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.127401 (rank : 224)
Query Neighborhood Hits	298	Target Neighborhood Hits	287	Shared Neighborhood Hits	106
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.116542 (rank : 263)
Query Neighborhood Hits	298	Target Neighborhood Hits	270	Shared Neighborhood Hits	92
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.112307 (rank : 278)
Query Neighborhood Hits	298	Target Neighborhood Hits	266	Shared Neighborhood Hits	91
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGF_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.141850 (rank : 193)
Query Neighborhood Hits	298	Target Neighborhood Hits	358	Shared Neighborhood Hits	128
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELTD1_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.062558 (rank : 412)
Query Neighborhood Hits	298	Target Neighborhood Hits	269	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.090613 (rank : 332)
Query Neighborhood Hits	298	Target Neighborhood Hits	288	Shared Neighborhood Hits	81
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.126326 (rank : 230)
Query Neighborhood Hits	298	Target Neighborhood Hits	382	Shared Neighborhood Hits	114
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.113720 (rank : 269)
Query Neighborhood Hits	298	Target Neighborhood Hits	349	Shared Neighborhood Hits	102
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.114739 (rank : 267)
Query Neighborhood Hits	298	Target Neighborhood Hits	345	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

ESM1_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.093491 (rank : 328)
Query Neighborhood Hits	298	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.084513 (rank : 348)
Query Neighborhood Hits	298	Target Neighborhood Hits	107	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FBLN1_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.176367 (rank : 135)
Query Neighborhood Hits	298	Target Neighborhood Hits	324	Shared Neighborhood Hits	125
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.146813 (rank : 186)
Query Neighborhood Hits	298	Target Neighborhood Hits	293	Shared Neighborhood Hits	121
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.141426 (rank : 195)
Query Neighborhood Hits	298	Target Neighborhood Hits	279	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.154877 (rank : 170)
Query Neighborhood Hits	298	Target Neighborhood Hits	278	Shared Neighborhood Hits	111
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.155315 (rank : 169)
Query Neighborhood Hits	298	Target Neighborhood Hits	270	Shared Neighborhood Hits	108
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.164621 (rank : 155)
Query Neighborhood Hits	298	Target Neighborhood Hits	329	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.168695 (rank : 147)
Query Neighborhood Hits	298	Target Neighborhood Hits	317	Shared Neighborhood Hits	131
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FREM1_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.055345 (rank : 430)
Query Neighborhood Hits	298	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM1_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.054506 (rank : 432)
Query Neighborhood Hits	298	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM2_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.069537 (rank : 392)
Query Neighborhood Hits	298	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM2_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.070369 (rank : 388)
Query Neighborhood Hits	298	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

FREM3_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.061247 (rank : 417)
Query Neighborhood Hits	298	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM3_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.061179 (rank : 418)
Query Neighborhood Hits	298	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

FST_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.053017 (rank : 435)
Query Neighborhood Hits	298	Target Neighborhood Hits	129	Shared Neighborhood Hits	45
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.057162 (rank : 427)
Query Neighborhood Hits	298	Target Neighborhood Hits	146	Shared Neighborhood Hits	54
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GAS6_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.138569 (rank : 199)
Query Neighborhood Hits	298	Target Neighborhood Hits	348	Shared Neighborhood Hits	124
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.137522 (rank : 202)
Query Neighborhood Hits	298	Target Neighborhood Hits	343	Shared Neighborhood Hits	126
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GRN_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.150416 (rank : 177)
Query Neighborhood Hits	298	Target Neighborhood Hits	268	Shared Neighborhood Hits	116
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.147477 (rank : 184)
Query Neighborhood Hits	298	Target Neighborhood Hits	248	Shared Neighborhood Hits	106
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HABP2_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.054656 (rank : 431)
Query Neighborhood Hits	298	Target Neighborhood Hits	431	Shared Neighborhood Hits	114
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.051880 (rank : 440)
Query Neighborhood Hits	298	Target Neighborhood Hits	445	Shared Neighborhood Hits	110
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HHIP_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.126671 (rank : 228)
Query Neighborhood Hits	298	Target Neighborhood Hits	249	Shared Neighborhood Hits	113
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.122726 (rank : 244)
Query Neighborhood Hits	298	Target Neighborhood Hits	219	Shared Neighborhood Hits	104
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB1_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.116829 (rank : 262)
Query Neighborhood Hits	298	Target Neighborhood Hits	298	Shared Neighborhood Hits	130
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.116887 (rank : 261)
Query Neighborhood Hits	298	Target Neighborhood Hits	283	Shared Neighborhood Hits	125
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.131709 (rank : 213)
Query Neighborhood Hits	298	Target Neighborhood Hits	326	Shared Neighborhood Hits	141
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.127556 (rank : 223)
Query Neighborhood Hits	298	Target Neighborhood Hits	325	Shared Neighborhood Hits	140
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.124545 (rank : 235)
Query Neighborhood Hits	298	Target Neighborhood Hits	319	Shared Neighborhood Hits	136
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB4_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.111167 (rank : 282)
Query Neighborhood Hits	298	Target Neighborhood Hits	458	Shared Neighborhood Hits	132
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.130233 (rank : 216)
Query Neighborhood Hits	298	Target Neighborhood Hits	310	Shared Neighborhood Hits	129
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.134699 (rank : 205)
Query Neighborhood Hits	298	Target Neighborhood Hits	329	Shared Neighborhood Hits	142
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.118151 (rank : 258)
Query Neighborhood Hits	298	Target Neighborhood Hits	318	Shared Neighborhood Hits	134
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.124206 (rank : 236)
Query Neighborhood Hits	298	Target Neighborhood Hits	341	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.129667 (rank : 217)
Query Neighborhood Hits	298	Target Neighborhood Hits	290	Shared Neighborhood Hits	129
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.128059 (rank : 221)
Query Neighborhood Hits	298	Target Neighborhood Hits	277	Shared Neighborhood Hits	124
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.104394 (rank : 300)
Query Neighborhood Hits	298	Target Neighborhood Hits	280	Shared Neighborhood Hits	118
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KR101_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.164583 (rank : 156)
Query Neighborhood Hits	298	Target Neighborhood Hits	261	Shared Neighborhood Hits	107
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.143396 (rank : 191)
Query Neighborhood Hits	298	Target Neighborhood Hits	264	Shared Neighborhood Hits	110
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.108250 (rank : 289)
Query Neighborhood Hits	298	Target Neighborhood Hits	212	Shared Neighborhood Hits	89
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR104_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.192916 (rank : 100)
Query Neighborhood Hits	298	Target Neighborhood Hits	313	Shared Neighborhood Hits	118
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.155922 (rank : 165)
Query Neighborhood Hits	298	Target Neighborhood Hits	271	Shared Neighborhood Hits	113
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR107_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.195434 (rank : 97)
Query Neighborhood Hits	298	Target Neighborhood Hits	330	Shared Neighborhood Hits	134
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.160292 (rank : 161)
Query Neighborhood Hits	298	Target Neighborhood Hits	226	Shared Neighborhood Hits	102
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.138249 (rank : 200)
Query Neighborhood Hits	298	Target Neighborhood Hits	226	Shared Neighborhood Hits	92
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.112519 (rank : 276)
Query Neighborhood Hits	298	Target Neighborhood Hits	232	Shared Neighborhood Hits	97
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10C_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.133829 (rank : 207)
Query Neighborhood Hits	298	Target Neighborhood Hits	219	Shared Neighborhood Hits	101
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.183593 (rank : 122)
Query Neighborhood Hits	298	Target Neighborhood Hits	144	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR410_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.105740 (rank : 297)
Query Neighborhood Hits	298	Target Neighborhood Hits	156	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.125879 (rank : 231)
Query Neighborhood Hits	298	Target Neighborhood Hits	178	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.067241 (rank : 398)
Query Neighborhood Hits	298	Target Neighborhood Hits	112	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.118083 (rank : 259)
Query Neighborhood Hits	298	Target Neighborhood Hits	199	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.234235 (rank : 50)
Query Neighborhood Hits	298	Target Neighborhood Hits	217	Shared Neighborhood Hits	93
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.204491 (rank : 83)
Query Neighborhood Hits	298	Target Neighborhood Hits	231	Shared Neighborhood Hits	92
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA15_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.110014 (rank : 285)
Query Neighborhood Hits	298	Target Neighborhood Hits	126	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.068883 (rank : 393)
Query Neighborhood Hits	298	Target Neighborhood Hits	192	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA42_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.085132 (rank : 346)
Query Neighborhood Hits	298	Target Neighborhood Hits	149	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.129395 (rank : 218)
Query Neighborhood Hits	298	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.160348 (rank : 160)
Query Neighborhood Hits	298	Target Neighborhood Hits	194	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA56_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.215332 (rank : 63)
Query Neighborhood Hits	298	Target Neighborhood Hits	207	Shared Neighborhood Hits	92
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.219772 (rank : 59)
Query Neighborhood Hits	298	Target Neighborhood Hits	269	Shared Neighborhood Hits	113
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA93_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.154196 (rank : 172)
Query Neighborhood Hits	298	Target Neighborhood Hits	203	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.132060 (rank : 211)
Query Neighborhood Hits	298	Target Neighborhood Hits	204	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.147915 (rank : 183)
Query Neighborhood Hits	298	Target Neighborhood Hits	185	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.126329 (rank : 229)
Query Neighborhood Hits	298	Target Neighborhood Hits	173	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LCE1A_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.103109 (rank : 305)
Query Neighborhood Hits	298	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.123060 (rank : 241)
Query Neighborhood Hits	298	Target Neighborhood Hits	58	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.132606 (rank : 209)
Query Neighborhood Hits	298	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.104599 (rank : 299)
Query Neighborhood Hits	298	Target Neighborhood Hits	44	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.112651 (rank : 274)
Query Neighborhood Hits	298	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.119140 (rank : 253)
Query Neighborhood Hits	298	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.124912 (rank : 232)
Query Neighborhood Hits	298	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.110066 (rank : 284)
Query Neighborhood Hits	298	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.112981 (rank : 272)
Query Neighborhood Hits	298	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.111483 (rank : 280)
Query Neighborhood Hits	298	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.099629 (rank : 314)
Query Neighborhood Hits	298	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE4A_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.064857 (rank : 403)
Query Neighborhood Hits	298	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.093251 (rank : 329)
Query Neighborhood Hits	298	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LDLR_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.126997 (rank : 227)
Query Neighborhood Hits	298	Target Neighborhood Hits	375	Shared Neighborhood Hits	133
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.122885 (rank : 243)
Query Neighborhood Hits	298	Target Neighborhood Hits	382	Shared Neighborhood Hits	127
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LORI_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.065871 (rank : 401)
Query Neighborhood Hits	298	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRP4_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.110499 (rank : 283)
Query Neighborhood Hits	298	Target Neighborhood Hits	355	Shared Neighborhood Hits	111
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.108363 (rank : 288)
Query Neighborhood Hits	298	Target Neighborhood Hits	351	Shared Neighborhood Hits	111
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.108239 (rank : 291)
Query Neighborhood Hits	298	Target Neighborhood Hits	346	Shared Neighborhood Hits	109
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.118220 (rank : 257)
Query Neighborhood Hits	298	Target Neighborhood Hits	385	Shared Neighborhood Hits	121
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LYAM1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.063173 (rank : 410)
Query Neighborhood Hits	298	Target Neighborhood Hits	315	Shared Neighborhood Hits	91
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.094137 (rank : 327)
Query Neighborhood Hits	298	Target Neighborhood Hits	394	Shared Neighborhood Hits	122
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.085874 (rank : 343)
Query Neighborhood Hits	298	Target Neighborhood Hits	378	Shared Neighborhood Hits	114
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.101110 (rank : 311)
Query Neighborhood Hits	298	Target Neighborhood Hits	390	Shared Neighborhood Hits	117
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MATN2_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.174002 (rank : 141)
Query Neighborhood Hits	298	Target Neighborhood Hits	365	Shared Neighborhood Hits	129
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.132504 (rank : 210)
Query Neighborhood Hits	298	Target Neighborhood Hits	268	Shared Neighborhood Hits	96
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.122124 (rank : 245)
Query Neighborhood Hits	298	Target Neighborhood Hits	261	Shared Neighborhood Hits	100
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.119645 (rank : 249)
Query Neighborhood Hits	298	Target Neighborhood Hits	287	Shared Neighborhood Hits	112
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.122903 (rank : 242)
Query Neighborhood Hits	298	Target Neighborhood Hits	277	Shared Neighborhood Hits	107
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCSP_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.063445 (rank : 407)
Query Neighborhood Hits	298	Target Neighborhood Hits	108	Shared Neighborhood Hits	39
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MFGM_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.067772 (rank : 396)
Query Neighborhood Hits	298	Target Neighborhood Hits	233	Shared Neighborhood Hits	92
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MT1A_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.077873 (rank : 373)
Query Neighborhood Hits	298	Target Neighborhood Hits	74	Shared Neighborhood Hits	26
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.057236 (rank : 426)
Query Neighborhood Hits	298	Target Neighborhood Hits	87	Shared Neighborhood Hits	30
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1E_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.051196 (rank : 443)
Query Neighborhood Hits	298	Target Neighborhood Hits	75	Shared Neighborhood Hits	24
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1F_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.051202 (rank : 442)
Query Neighborhood Hits	298	Target Neighborhood Hits	73	Shared Neighborhood Hits	24
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1G_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.073211 (rank : 384)
Query Neighborhood Hits	298	Target Neighborhood Hits	63	Shared Neighborhood Hits	25
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT1H_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.068610 (rank : 395)
Query Neighborhood Hits	298	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1L_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.071986 (rank : 386)
Query Neighborhood Hits	298	Target Neighborhood Hits	73	Shared Neighborhood Hits	23
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1X_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.078531 (rank : 370)
Query Neighborhood Hits	298	Target Neighborhood Hits	76	Shared Neighborhood Hits	33
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.075068 (rank : 378)
Query Neighborhood Hits	298	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.052732 (rank : 438)
Query Neighborhood Hits	298	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MT2_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.087223 (rank : 340)
Query Neighborhood Hits	298	Target Neighborhood Hits	81	Shared Neighborhood Hits	28
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.108427 (rank : 287)
Query Neighborhood Hits	298	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.121021 (rank : 247)
Query Neighborhood Hits	298	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.078990 (rank : 367)
Query Neighborhood Hits	298	Target Neighborhood Hits	83	Shared Neighborhood Hits	32
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.092802 (rank : 330)
Query Neighborhood Hits	298	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.062017 (rank : 414)
Query Neighborhood Hits	298	Target Neighborhood Hits	447	Shared Neighborhood Hits	85
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC2_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.088389 (rank : 338)
Query Neighborhood Hits	298	Target Neighborhood Hits	906	Shared Neighborhood Hits	106
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NET1_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.149197 (rank : 179)
Query Neighborhood Hits	298	Target Neighborhood Hits	149	Shared Neighborhood Hits	78
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.148857 (rank : 181)
Query Neighborhood Hits	298	Target Neighborhood Hits	151	Shared Neighborhood Hits	80
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET4_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.166893 (rank : 152)
Query Neighborhood Hits	298	Target Neighborhood Hits	191	Shared Neighborhood Hits	102
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.167497 (rank : 151)
Query Neighborhood Hits	298	Target Neighborhood Hits	180	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NFX1_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.139250 (rank : 198)
Query Neighborhood Hits	298	Target Neighborhood Hits	405	Shared Neighborhood Hits	116
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.143875 (rank : 190)
Query Neighborhood Hits	298	Target Neighborhood Hits	329	Shared Neighborhood Hits	120
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.145344 (rank : 188)
Query Neighborhood Hits	298	Target Neighborhood Hits	335	Shared Neighborhood Hits	120
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NRX1A_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.053267 (rank : 434)
Query Neighborhood Hits	298	Target Neighborhood Hits	170	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.052740 (rank : 437)
Query Neighborhood Hits	298	Target Neighborhood Hits	164	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NTNG1_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.174995 (rank : 139)
Query Neighborhood Hits	298	Target Neighborhood Hits	247	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.171201 (rank : 145)
Query Neighborhood Hits	298	Target Neighborhood Hits	246	Shared Neighborhood Hits	116
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.176950 (rank : 133)
Query Neighborhood Hits	298	Target Neighborhood Hits	276	Shared Neighborhood Hits	121
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.169670 (rank : 146)
Query Neighborhood Hits	298	Target Neighborhood Hits	276	Shared Neighborhood Hits	120
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PERT_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.057654 (rank : 424)
Query Neighborhood Hits	298	Target Neighborhood Hits	221	Shared Neighborhood Hits	68
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.053344 (rank : 433)
Query Neighborhood Hits	298	Target Neighborhood Hits	221	Shared Neighborhood Hits	68
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PROS_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.142504 (rank : 192)
Query Neighborhood Hits	298	Target Neighborhood Hits	340	Shared Neighborhood Hits	125
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.141797 (rank : 194)
Query Neighborhood Hits	298	Target Neighborhood Hits	330	Shared Neighborhood Hits	120
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.081888 (rank : 356)
Query Neighborhood Hits	298	Target Neighborhood Hits	422	Shared Neighborhood Hits	107
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.083242 (rank : 353)
Query Neighborhood Hits	298	Target Neighborhood Hits	410	Shared Neighborhood Hits	101
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RECK_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.070144 (rank : 389)
Query Neighborhood Hits	298	Target Neighborhood Hits	189	Shared Neighborhood Hits	63
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

SLIT1_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.118373 (rank : 255)
Query Neighborhood Hits	298	Target Neighborhood Hits	700	Shared Neighborhood Hits	141
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.118356 (rank : 256)
Query Neighborhood Hits	298	Target Neighborhood Hits	715	Shared Neighborhood Hits	143
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.113875 (rank : 268)
Query Neighborhood Hits	298	Target Neighborhood Hits	708	Shared Neighborhood Hits	143
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.111906 (rank : 279)
Query Neighborhood Hits	298	Target Neighborhood Hits	684	Shared Neighborhood Hits	134
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.112443 (rank : 277)
Query Neighborhood Hits	298	Target Neighborhood Hits	700	Shared Neighborhood Hits	145
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SORL_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.098742 (rank : 315)
Query Neighborhood Hits	298	Target Neighborhood Hits	440	Shared Neighborhood Hits	120
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.103572 (rank : 303)
Query Neighborhood Hits	298	Target Neighborhood Hits	439	Shared Neighborhood Hits	127
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SUSD1_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.127043 (rank : 226)
Query Neighborhood Hits	298	Target Neighborhood Hits	285	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.062555 (rank : 413)
Query Neighborhood Hits	298	Target Neighborhood Hits	132	Shared Neighborhood Hits	55
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.079215 (rank : 366)
Query Neighborhood Hits	298	Target Neighborhood Hits	146	Shared Neighborhood Hits	69
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.063531 (rank : 406)
Query Neighborhood Hits	298	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TEFF2_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.061992 (rank : 415)
Query Neighborhood Hits	298	Target Neighborhood Hits	211	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.063328 (rank : 408)
Query Neighborhood Hits	298	Target Neighborhood Hits	214	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENA_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.168592 (rank : 149)
Query Neighborhood Hits	298	Target Neighborhood Hits	596	Shared Neighborhood Hits	149
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.078982 (rank : 368)
Query Neighborhood Hits	298	Target Neighborhood Hits	453	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.085728 (rank : 344)
Query Neighborhood Hits	298	Target Neighborhood Hits	484	Shared Neighborhood Hits	129
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.108247 (rank : 290)
Query Neighborhood Hits	298	Target Neighborhood Hits	526	Shared Neighborhood Hits	142
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.103517 (rank : 304)
Query Neighborhood Hits	298	Target Neighborhood Hits	531	Shared Neighborhood Hits	138
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TNR11_MOUSE
θ value	θ > 10 (rank : 502)	NC score	0.075642 (rank : 377)
Query Neighborhood Hits	298	Target Neighborhood Hits	121	Shared Neighborhood Hits	66
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR19_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.061138 (rank : 419)
Query Neighborhood Hits	298	Target Neighborhood Hits	89	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 504)	NC score	0.070417 (rank : 387)
Query Neighborhood Hits	298	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1B_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.106878 (rank : 294)
Query Neighborhood Hits	298	Target Neighborhood Hits	123	Shared Neighborhood Hits	56
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR21_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.070125 (rank : 390)
Query Neighborhood Hits	298	Target Neighborhood Hits	108	Shared Neighborhood Hits	59
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR22_MOUSE
θ value	θ > 10 (rank : 507)	NC score	0.104128 (rank : 301)
Query Neighborhood Hits	298	Target Neighborhood Hits	97	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR3_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.085281 (rank : 345)
Query Neighborhood Hits	298	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR5_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.106746 (rank : 295)
Query Neighborhood Hits	298	Target Neighborhood Hits	131	Shared Neighborhood Hits	77
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR6B_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.091513 (rank : 331)
Query Neighborhood Hits	298	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.074952 (rank : 379)
Query Neighborhood Hits	298	Target Neighborhood Hits	95	Shared Neighborhood Hits	56
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.089604 (rank : 335)
Query Neighborhood Hits	298	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.103719 (rank : 302)
Query Neighborhood Hits	298	Target Neighborhood Hits	120	Shared Neighborhood Hits	71
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR7_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.078670 (rank : 369)
Query Neighborhood Hits	298	Target Neighborhood Hits	112	Shared Neighborhood Hits	56
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR8_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.073232 (rank : 383)
Query Neighborhood Hits	298	Target Neighborhood Hits	208	Shared Neighborhood Hits	73
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.107469 (rank : 293)
Query Neighborhood Hits	298	Target Neighborhood Hits	166	Shared Neighborhood Hits	75
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TR10B_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.064716 (rank : 404)
Query Neighborhood Hits	298	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR10C_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.073913 (rank : 380)
Query Neighborhood Hits	298	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR10D_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.064058 (rank : 405)
Query Neighborhood Hits	298	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TRBM_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.167805 (rank : 150)
Query Neighborhood Hits	298	Target Neighborhood Hits	339	Shared Neighborhood Hits	123
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP1_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.124652 (rank : 233)
Query Neighborhood Hits	298	Target Neighborhood Hits	389	Shared Neighborhood Hits	142
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.123875 (rank : 237)
Query Neighborhood Hits	298	Target Neighborhood Hits	396	Shared Neighborhood Hits	144
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.101119 (rank : 310)
Query Neighborhood Hits	298	Target Neighborhood Hits	359	Shared Neighborhood Hits	130
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.104925 (rank : 298)
Query Neighborhood Hits	298	Target Neighborhood Hits	352	Shared Neighborhood Hits	128
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.119177 (rank : 252)
Query Neighborhood Hits	298	Target Neighborhood Hits	250	Shared Neighborhood Hits	104
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.121234 (rank : 246)
Query Neighborhood Hits	298	Target Neighborhood Hits	247	Shared Neighborhood Hits	110
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.128757 (rank : 219)
Query Neighborhood Hits	298	Target Neighborhood Hits	276	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROL1_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.063164 (rank : 411)
Query Neighborhood Hits	298	Target Neighborhood Hits	213	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.065202 (rank : 402)
Query Neighborhood Hits	298	Target Neighborhood Hits	235	Shared Neighborhood Hits	70
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

VEGFC_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.061414 (rank : 416)
Query Neighborhood Hits	298	Target Neighborhood Hits	119	Shared Neighborhood Hits	55
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VLDLR_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.120633 (rank : 248)
Query Neighborhood Hits	298	Target Neighborhood Hits	383	Shared Neighborhood Hits	122
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.119191 (rank : 251)
Query Neighborhood Hits	298	Target Neighborhood Hits	360	Shared Neighborhood Hits	116
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WFDC3_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.059816 (rank : 421)
Query Neighborhood Hits	298	Target Neighborhood Hits	138	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WIF1_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.184586 (rank : 117)
Query Neighborhood Hits	298	Target Neighborhood Hits	392	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.189866 (rank : 105)
Query Neighborhood Hits	298	Target Neighborhood Hits	393	Shared Neighborhood Hits	146
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

Hits sorted by NC score

PCSK6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	298	Target Neighborhood Hits	298	Shared Neighborhood Hits	298
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PCSK5_HUMAN
NC score	0.958747 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	298	Target Neighborhood Hits	291	Shared Neighborhood Hits	177
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

FURIN_MOUSE
NC score	0.904758 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	298	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

FURIN_HUMAN
NC score	0.903218 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	298	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

PCSK4_HUMAN
NC score	0.890260 (rank : 5)	θ value	2.49359e-167 (rank : 6)
Query Neighborhood Hits	298	Target Neighborhood Hits	32	Shared Neighborhood Hits	26
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PCSK5_MOUSE
NC score	0.883122 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	298	Target Neighborhood Hits	613	Shared Neighborhood Hits	217
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK4_MOUSE
NC score	0.878385 (rank : 7)	θ value	4.86655e-163 (rank : 9)
Query Neighborhood Hits	298	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

NEC1_HUMAN
NC score	0.875905 (rank : 8)	θ value	3.25673e-167 (rank : 7)
Query Neighborhood Hits	298	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

NEC1_MOUSE
NC score	0.875740 (rank : 9)	θ value	1.23756e-166 (rank : 8)
Query Neighborhood Hits	298	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	P63239, P21662, P22546	Gene names	Pcsk1, Att-1, Nec-1, Nec1
Domain Architecture	No domain graphic available
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1) (PC3) (Furin homolog) (Propeptide-processing protease).

NEC2_MOUSE
NC score	0.872443 (rank : 10)	θ value	3.06949e-141 (rank : 11)
Query Neighborhood Hits	298	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P21661, Q80WU1	Gene names	Pcsk2, Nec-2, Nec2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NEC2_HUMAN
NC score	0.872262 (rank : 11)	θ value	3.62588e-142 (rank : 10)
Query Neighborhood Hits	298	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P16519, Q14927, Q9NQG3, Q9NUG1, Q9UJC6	Gene names	PCSK2, NEC2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

PCSK7_HUMAN
NC score	0.864868 (rank : 12)	θ value	1.05987e-125 (rank : 13)
Query Neighborhood Hits	298	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

PCSK7_MOUSE
NC score	0.864788 (rank : 13)	θ value	3.89193e-128 (rank : 12)
Query Neighborhood Hits	298	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

FRAS1_HUMAN
NC score	0.386391 (rank : 14)	θ value	1.08979e-29 (rank : 15)
Query Neighborhood Hits	298	Target Neighborhood Hits	759	Shared Neighborhood Hits	213
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
NC score	0.380325 (rank : 15)	θ value	1.6813e-30 (rank : 14)
Query Neighborhood Hits	298	Target Neighborhood Hits	747	Shared Neighborhood Hits	211
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

RSPO3_HUMAN
NC score	0.346145 (rank : 16)	θ value	2.52405e-10 (rank : 18)
Query Neighborhood Hits	298	Target Neighborhood Hits	128	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
NC score	0.340776 (rank : 17)	θ value	4.30538e-10 (rank : 19)
Query Neighborhood Hits	298	Target Neighborhood Hits	120	Shared Neighborhood Hits	64
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
NC score	0.334053 (rank : 18)	θ value	6.21693e-09 (rank : 29)
Query Neighborhood Hits	298	Target Neighborhood Hits	110	Shared Neighborhood Hits	68
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
NC score	0.331780 (rank : 19)	θ value	1.63604e-09 (rank : 22)
Query Neighborhood Hits	298	Target Neighborhood Hits	110	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RSPO2_MOUSE
NC score	0.318209 (rank : 20)	θ value	1.29631e-06 (rank : 38)
Query Neighborhood Hits	298	Target Neighborhood Hits	88	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO2_HUMAN
NC score	0.317999 (rank : 21)	θ value	9.92553e-07 (rank : 37)
Query Neighborhood Hits	298	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO1_HUMAN
NC score	0.312790 (rank : 22)	θ value	1.38499e-08 (rank : 31)
Query Neighborhood Hits	298	Target Neighborhood Hits	101	Shared Neighborhood Hits	56
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

CREL1_HUMAN
NC score	0.312117 (rank : 23)	θ value	2.98157e-11 (rank : 16)
Query Neighborhood Hits	298	Target Neighborhood Hits	441	Shared Neighborhood Hits	159
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
NC score	0.310883 (rank : 24)	θ value	2.98157e-11 (rank : 17)
Query Neighborhood Hits	298	Target Neighborhood Hits	524	Shared Neighborhood Hits	172
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

RSPO1_MOUSE
NC score	0.296244 (rank : 25)	θ value	2.36244e-08 (rank : 32)
Query Neighborhood Hits	298	Target Neighborhood Hits	85	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

SREC2_MOUSE
NC score	0.295752 (rank : 26)	θ value	2.79066e-09 (rank : 24)
Query Neighborhood Hits	298	Target Neighborhood Hits	605	Shared Neighborhood Hits	182
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC2_HUMAN
NC score	0.293179 (rank : 27)	θ value	2.13673e-09 (rank : 23)
Query Neighborhood Hits	298	Target Neighborhood Hits	645	Shared Neighborhood Hits	179
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC_HUMAN
NC score	0.292256 (rank : 28)	θ value	5.26297e-08 (rank : 34)
Query Neighborhood Hits	298	Target Neighborhood Hits	645	Shared Neighborhood Hits	181
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

MEGF9_HUMAN
NC score	0.284976 (rank : 29)	θ value	9.29e-05 (rank : 49)
Query Neighborhood Hits	298	Target Neighborhood Hits	557	Shared Neighborhood Hits	168
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KRA51_HUMAN
NC score	0.284240 (rank : 30)	θ value	0.163984 (rank : 141)
Query Neighborhood Hits	298	Target Neighborhood Hits	288	Shared Neighborhood Hits	119
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

MEGF9_MOUSE
NC score	0.280043 (rank : 31)	θ value	7.59969e-07 (rank : 35)
Query Neighborhood Hits	298	Target Neighborhood Hits	896	Shared Neighborhood Hits	177
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KRA55_HUMAN
NC score	0.277759 (rank : 32)	θ value	0.0148317 (rank : 97)
Query Neighborhood Hits	298	Target Neighborhood Hits	257	Shared Neighborhood Hits	112
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

MEGF6_HUMAN
NC score	0.269721 (rank : 33)	θ value	9.92553e-07 (rank : 36)
Query Neighborhood Hits	298	Target Neighborhood Hits	671	Shared Neighborhood Hits	189
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KRA59_HUMAN
NC score	0.266620 (rank : 34)	θ value	0.0148317 (rank : 98)
Query Neighborhood Hits	298	Target Neighborhood Hits	310	Shared Neighborhood Hits	124
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

MEGF8_HUMAN
NC score	0.263279 (rank : 35)	θ value	0.000270298 (rank : 57)
Query Neighborhood Hits	298	Target Neighborhood Hits	528	Shared Neighborhood Hits	165
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KRA53_HUMAN
NC score	0.263024 (rank : 36)	θ value	0.62314 (rank : 170)
Query Neighborhood Hits	298	Target Neighborhood Hits	331	Shared Neighborhood Hits	136
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
NC score	0.262262 (rank : 37)	θ value	6.88961 (rank : 281)
Query Neighborhood Hits	298	Target Neighborhood Hits	270	Shared Neighborhood Hits	115
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

MEGF8_MOUSE
NC score	0.258764 (rank : 38)	θ value	0.000461057 (rank : 59)
Query Neighborhood Hits	298	Target Neighborhood Hits	520	Shared Neighborhood Hits	162
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KRA52_HUMAN
NC score	0.248375 (rank : 39)	θ value	0.0736092 (rank : 120)
Query Neighborhood Hits	298	Target Neighborhood Hits	236	Shared Neighborhood Hits	104
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LAMB2_HUMAN
NC score	0.248231 (rank : 40)	θ value	4.1701e-05 (rank : 43)
Query Neighborhood Hits	298	Target Neighborhood Hits	692	Shared Neighborhood Hits	167
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

KRA58_HUMAN
NC score	0.246348 (rank : 41)	θ value	1.06291 (rank : 188)
Query Neighborhood Hits	298	Target Neighborhood Hits	324	Shared Neighborhood Hits	127
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

ZAN_MOUSE
NC score	0.246341 (rank : 42)	θ value	0.000602161 (rank : 64)
Query Neighborhood Hits	298	Target Neighborhood Hits	808	Shared Neighborhood Hits	188
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LAMA5_MOUSE
NC score	0.244434 (rank : 43)	θ value	0.000602161 (rank : 61)
Query Neighborhood Hits	298	Target Neighborhood Hits	828	Shared Neighborhood Hits	182
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC3_HUMAN
NC score	0.244205 (rank : 44)	θ value	7.1131e-05 (rank : 45)
Query Neighborhood Hits	298	Target Neighborhood Hits	588	Shared Neighborhood Hits	171
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMB2_MOUSE
NC score	0.243659 (rank : 45)	θ value	0.000602161 (rank : 62)
Query Neighborhood Hits	298	Target Neighborhood Hits	722	Shared Neighborhood Hits	164
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMA1_HUMAN
NC score	0.239676 (rank : 46)	θ value	0.000270298 (rank : 55)
Query Neighborhood Hits	298	Target Neighborhood Hits	804	Shared Neighborhood Hits	179
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA5_HUMAN
NC score	0.239642 (rank : 47)	θ value	0.00228821 (rank : 78)
Query Neighborhood Hits	298	Target Neighborhood Hits	976	Shared Neighborhood Hits	188
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA1_MOUSE
NC score	0.239476 (rank : 48)	θ value	0.000158464 (rank : 52)
Query Neighborhood Hits	298	Target Neighborhood Hits	838	Shared Neighborhood Hits	178
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC3_MOUSE
NC score	0.239098 (rank : 49)	θ value	0.000270298 (rank : 56)
Query Neighborhood Hits	298	Target Neighborhood Hits	624	Shared Neighborhood Hits	176
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

KR510_HUMAN
NC score	0.234235 (rank : 50)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	298	Target Neighborhood Hits	217	Shared Neighborhood Hits	93
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

LAMB1_MOUSE
NC score	0.232206 (rank : 51)	θ value	4.0297e-08 (rank : 33)
Query Neighborhood Hits	298	Target Neighborhood Hits	919	Shared Neighborhood Hits	157
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

CRIM1_HUMAN
NC score	0.231771 (rank : 52)	θ value	0.0113563 (rank : 93)
Query Neighborhood Hits	298	Target Neighborhood Hits	362	Shared Neighborhood Hits	132
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

USH2A_MOUSE
NC score	0.226534 (rank : 53)	θ value	7.1131e-05 (rank : 47)
Query Neighborhood Hits	298	Target Neighborhood Hits	626	Shared Neighborhood Hits	167
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

STAB1_HUMAN
NC score	0.223041 (rank : 54)	θ value	0.00175202 (rank : 75)
Query Neighborhood Hits	298	Target Neighborhood Hits	546	Shared Neighborhood Hits	164
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
NC score	0.221819 (rank : 55)	θ value	0.0330416 (rank : 108)
Query Neighborhood Hits	298	Target Neighborhood Hits	566	Shared Neighborhood Hits	163
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
NC score	0.221548 (rank : 56)	θ value	0.00134147 (rank : 70)
Query Neighborhood Hits	298	Target Neighborhood Hits	534	Shared Neighborhood Hits	168
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LAMA2_HUMAN
NC score	0.221325 (rank : 57)	θ value	0.000602161 (rank : 60)
Query Neighborhood Hits	298	Target Neighborhood Hits	1092	Shared Neighborhood Hits	182
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

STAB2_MOUSE
NC score	0.220788 (rank : 58)	θ value	0.00665767 (rank : 86)
Query Neighborhood Hits	298	Target Neighborhood Hits	528	Shared Neighborhood Hits	165
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

KRA57_HUMAN
NC score	0.219772 (rank : 59)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	298	Target Neighborhood Hits	269	Shared Neighborhood Hits	113
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

LAMB1_HUMAN
NC score	0.218847 (rank : 60)	θ value	0.000158464 (rank : 53)
Query Neighborhood Hits	298	Target Neighborhood Hits	1018	Shared Neighborhood Hits	158
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NELL1_HUMAN
NC score	0.218269 (rank : 61)	θ value	0.0113563 (rank : 94)
Query Neighborhood Hits	298	Target Neighborhood Hits	451	Shared Neighborhood Hits	158
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

LAMC2_MOUSE
NC score	0.217194 (rank : 62)	θ value	0.47712 (rank : 165)
Query Neighborhood Hits	298	Target Neighborhood Hits	614	Shared Neighborhood Hits	170
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

KRA56_HUMAN
NC score	0.215332 (rank : 63)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	298	Target Neighborhood Hits	207	Shared Neighborhood Hits	92
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LAMB3_MOUSE
NC score	0.214752 (rank : 64)	θ value	0.47712 (rank : 164)
Query Neighborhood Hits	298	Target Neighborhood Hits	444	Shared Neighborhood Hits	133
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

FBN3_HUMAN
NC score	0.213644 (rank : 65)	θ value	0.00228821 (rank : 77)
Query Neighborhood Hits	298	Target Neighborhood Hits	543	Shared Neighborhood Hits	171
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LTBP2_MOUSE
NC score	0.213428 (rank : 66)	θ value	0.00869519 (rank : 88)
Query Neighborhood Hits	298	Target Neighborhood Hits	617	Shared Neighborhood Hits	154
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN1_HUMAN
NC score	0.213066 (rank : 67)	θ value	0.00665767 (rank : 83)
Query Neighborhood Hits	298	Target Neighborhood Hits	557	Shared Neighborhood Hits	177
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
NC score	0.212527 (rank : 68)	θ value	0.00228821 (rank : 76)
Query Neighborhood Hits	298	Target Neighborhood Hits	560	Shared Neighborhood Hits	176
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.212256 (rank : 69)	θ value	0.0193708 (rank : 100)
Query Neighborhood Hits	298	Target Neighborhood Hits	563	Shared Neighborhood Hits	175
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LAMC1_MOUSE
NC score	0.211563 (rank : 70)	θ value	0.0148317 (rank : 99)
Query Neighborhood Hits	298	Target Neighborhood Hits	856	Shared Neighborhood Hits	168
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SCUB3_MOUSE
NC score	0.211031 (rank : 71)	θ value	7.1131e-05 (rank : 46)
Query Neighborhood Hits	298	Target Neighborhood Hits	442	Shared Neighborhood Hits	162
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NELL2_HUMAN
NC score	0.210634 (rank : 72)	θ value	0.0431538 (rank : 111)
Query Neighborhood Hits	298	Target Neighborhood Hits	449	Shared Neighborhood Hits	147
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

LAMA2_MOUSE
NC score	0.209655 (rank : 73)	θ value	0.0563607 (rank : 116)
Query Neighborhood Hits	298	Target Neighborhood Hits	1198	Shared Neighborhood Hits	170
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

SCUB3_HUMAN
NC score	0.209246 (rank : 74)	θ value	5.44631e-05 (rank : 44)
Query Neighborhood Hits	298	Target Neighborhood Hits	428	Shared Neighborhood Hits	157
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

FBN2_MOUSE
NC score	0.209191 (rank : 75)	θ value	0.47712 (rank : 162)
Query Neighborhood Hits	298	Target Neighborhood Hits	549	Shared Neighborhood Hits	177
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LAMC1_HUMAN
NC score	0.208937 (rank : 76)	θ value	0.00665767 (rank : 84)
Query Neighborhood Hits	298	Target Neighborhood Hits	922	Shared Neighborhood Hits	173
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NELL2_MOUSE
NC score	0.208742 (rank : 77)	θ value	0.365318 (rank : 158)
Query Neighborhood Hits	298	Target Neighborhood Hits	436	Shared Neighborhood Hits	145
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

USH2A_HUMAN
NC score	0.208561 (rank : 78)	θ value	0.0193708 (rank : 102)
Query Neighborhood Hits	298	Target Neighborhood Hits	600	Shared Neighborhood Hits	154
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LTBP4_MOUSE
NC score	0.208241 (rank : 79)	θ value	0.163984 (rank : 142)
Query Neighborhood Hits	298	Target Neighborhood Hits	607	Shared Neighborhood Hits	161
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LAMB3_HUMAN
NC score	0.207465 (rank : 80)	θ value	3.0926 (rank : 232)
Query Neighborhood Hits	298	Target Neighborhood Hits	461	Shared Neighborhood Hits	127
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

JAG1_HUMAN
NC score	0.205882 (rank : 81)	θ value	0.0330416 (rank : 105)
Query Neighborhood Hits	298	Target Neighborhood Hits	514	Shared Neighborhood Hits	150
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

LTBP2_HUMAN
NC score	0.204782 (rank : 82)	θ value	1.81305 (rank : 210)
Query Neighborhood Hits	298	Target Neighborhood Hits	552	Shared Neighborhood Hits	157
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KR511_HUMAN
NC score	0.204491 (rank : 83)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	298	Target Neighborhood Hits	231	Shared Neighborhood Hits	92
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

NOTC1_MOUSE
NC score	0.204455 (rank : 84)	θ value	0.00509761 (rank : 81)
Query Neighborhood Hits	298	Target Neighborhood Hits	916	Shared Neighborhood Hits	165
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LAMC2_HUMAN
NC score	0.204122 (rank : 85)	θ value	0.813845 (rank : 178)
Query Neighborhood Hits	298	Target Neighborhood Hits	715	Shared Neighborhood Hits	157
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

JAG1_MOUSE
NC score	0.204121 (rank : 86)	θ value	0.0330416 (rank : 106)
Query Neighborhood Hits	298	Target Neighborhood Hits	518	Shared Neighborhood Hits	151
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

DLL4_MOUSE
NC score	0.202394 (rank : 87)	θ value	0.000121331 (rank : 50)
Query Neighborhood Hits	298	Target Neighborhood Hits	440	Shared Neighborhood Hits	150
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

JAG2_HUMAN
NC score	0.201962 (rank : 88)	θ value	2.36792 (rank : 219)
Query Neighborhood Hits	298	Target Neighborhood Hits	491	Shared Neighborhood Hits	148
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

LAMA3_MOUSE
NC score	0.200557 (rank : 89)	θ value	0.62314 (rank : 171)
Query Neighborhood Hits	298	Target Neighborhood Hits	859	Shared Neighborhood Hits	169
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

JAG2_MOUSE
NC score	0.199891 (rank : 90)	θ value	0.47712 (rank : 163)
Query Neighborhood Hits	298	Target Neighborhood Hits	504	Shared Neighborhood Hits	147
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

AGRIN_HUMAN
NC score	0.199777 (rank : 91)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	298	Target Neighborhood Hits	582	Shared Neighborhood Hits	152
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NOTC1_HUMAN
NC score	0.197662 (rank : 92)	θ value	0.0563607 (rank : 117)
Query Neighborhood Hits	298	Target Neighborhood Hits	906	Shared Neighborhood Hits	166
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

KR106_HUMAN
NC score	0.197173 (rank : 93)	θ value	0.163984 (rank : 140)
Query Neighborhood Hits	298	Target Neighborhood Hits	347	Shared Neighborhood Hits	137
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

LTB1L_HUMAN
NC score	0.196571 (rank : 94)	θ value	0.00134147 (rank : 68)
Query Neighborhood Hits	298	Target Neighborhood Hits	553	Shared Neighborhood Hits	153
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.196182 (rank : 95)	θ value	0.00134147 (rank : 69)
Query Neighborhood Hits	298	Target Neighborhood Hits	502	Shared Neighborhood Hits	146
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DLL4_HUMAN
NC score	0.195901 (rank : 96)	θ value	0.163984 (rank : 138)
Query Neighborhood Hits	298	Target Neighborhood Hits	435	Shared Neighborhood Hits	151
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

KR107_HUMAN
NC score	0.195434 (rank : 97)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	298	Target Neighborhood Hits	330	Shared Neighborhood Hits	134
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

DLL1_MOUSE
NC score	0.193909 (rank : 98)	θ value	5.27518 (rank : 261)
Query Neighborhood Hits	298	Target Neighborhood Hits	456	Shared Neighborhood Hits	151
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

LTB1S_MOUSE
NC score	0.193767 (rank : 99)	θ value	0.00175202 (rank : 74)
Query Neighborhood Hits	298	Target Neighborhood Hits	479	Shared Neighborhood Hits	149
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

KR104_HUMAN
NC score	0.192916 (rank : 100)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	298	Target Neighborhood Hits	313	Shared Neighborhood Hits	118
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LTB1L_MOUSE
NC score	0.192913 (rank : 101)	θ value	0.00175202 (rank : 73)
Query Neighborhood Hits	298	Target Neighborhood Hits	514	Shared Neighborhood Hits	157
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NOTC3_HUMAN
NC score	0.192678 (rank : 102)	θ value	0.0431538 (rank : 112)
Query Neighborhood Hits	298	Target Neighborhood Hits	1062	Shared Neighborhood Hits	165
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
NC score	0.190875 (rank : 103)	θ value	0.0563607 (rank : 118)
Query Neighborhood Hits	298	Target Neighborhood Hits	975	Shared Neighborhood Hits	158
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LAMA4_MOUSE
NC score	0.190241 (rank : 104)	θ value	1.06291 (rank : 189)
Query Neighborhood Hits	298	Target Neighborhood Hits	584	Shared Neighborhood Hits	123
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

WIF1_MOUSE
NC score	0.189866 (rank : 105)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	298	Target Neighborhood Hits	393	Shared Neighborhood Hits	146
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

DLL1_HUMAN
NC score	0.189772 (rank : 106)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	298	Target Neighborhood Hits	455	Shared Neighborhood Hits	150
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

NOTC4_HUMAN
NC score	0.189691 (rank : 107)	θ value	0.0736092 (rank : 123)
Query Neighborhood Hits	298	Target Neighborhood Hits	905	Shared Neighborhood Hits	164
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

FBLN2_HUMAN
NC score	0.189187 (rank : 108)	θ value	0.279714 (rank : 153)
Query Neighborhood Hits	298	Target Neighborhood Hits	392	Shared Neighborhood Hits	130
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LTBP3_MOUSE
NC score	0.187337 (rank : 109)	θ value	5.27518 (rank : 264)
Query Neighborhood Hits	298	Target Neighborhood Hits	475	Shared Neighborhood Hits	146
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NOTC2_MOUSE
NC score	0.186929 (rank : 110)	θ value	0.125558 (rank : 134)
Query Neighborhood Hits	298	Target Neighborhood Hits	1069	Shared Neighborhood Hits	153
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.186060 (rank : 111)	θ value	0.21417 (rank : 148)
Query Neighborhood Hits	298	Target Neighborhood Hits	1113	Shared Neighborhood Hits	161
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CRUM1_HUMAN
NC score	0.185980 (rank : 112)	θ value	0.000461057 (rank : 58)
Query Neighborhood Hits	298	Target Neighborhood Hits	457	Shared Neighborhood Hits	142
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FBLN2_MOUSE
NC score	0.185592 (rank : 113)	θ value	0.000121331 (rank : 51)
Query Neighborhood Hits	298	Target Neighborhood Hits	505	Shared Neighborhood Hits	134
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LAMA3_HUMAN
NC score	0.185003 (rank : 114)	θ value	0.0736092 (rank : 121)
Query Neighborhood Hits	298	Target Neighborhood Hits	760	Shared Neighborhood Hits	143
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

NOTC4_MOUSE
NC score	0.184981 (rank : 115)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	298	Target Neighborhood Hits	872	Shared Neighborhood Hits	160
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NAGPA_HUMAN
NC score	0.184809 (rank : 116)	θ value	0.62314 (rank : 173)
Query Neighborhood Hits	298	Target Neighborhood Hits	282	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

WIF1_HUMAN
NC score	0.184586 (rank : 117)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	298	Target Neighborhood Hits	392	Shared Neighborhood Hits	145
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

DNER_HUMAN
NC score	0.184422 (rank : 118)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	298	Target Neighborhood Hits	460	Shared Neighborhood Hits	140
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

CRUM1_MOUSE
NC score	0.184157 (rank : 119)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	298	Target Neighborhood Hits	444	Shared Neighborhood Hits	140
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

EGFL9_HUMAN
NC score	0.183945 (rank : 120)	θ value	0.0563607 (rank : 115)
Query Neighborhood Hits	298	Target Neighborhood Hits	365	Shared Neighborhood Hits	135
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

LTBP3_HUMAN
NC score	0.183907 (rank : 121)	θ value	5.27518 (rank : 263)
Query Neighborhood Hits	298	Target Neighborhood Hits	502	Shared Neighborhood Hits	155
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

KR171_HUMAN
NC score	0.183593 (rank : 122)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	298	Target Neighborhood Hits	144	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

EGFL9_MOUSE
NC score	0.181722 (rank : 123)	θ value	0.125558 (rank : 133)
Query Neighborhood Hits	298	Target Neighborhood Hits	379	Shared Neighborhood Hits	135
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

LAMA4_HUMAN
NC score	0.181632 (rank : 124)	θ value	0.0961366 (rank : 127)
Query Neighborhood Hits	298	Target Neighborhood Hits	708	Shared Neighborhood Hits	121
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TENX_HUMAN
NC score	0.181115 (rank : 125)	θ value	0.0563607 (rank : 119)
Query Neighborhood Hits	298	Target Neighborhood Hits	789	Shared Neighborhood Hits	158
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

CRUM2_HUMAN
NC score	0.180973 (rank : 126)	θ value	1.81305 (rank : 206)
Query Neighborhood Hits	298	Target Neighborhood Hits	453	Shared Neighborhood Hits	142
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

FBLN1_MOUSE
NC score	0.180410 (rank : 127)	θ value	0.279714 (rank : 152)
Query Neighborhood Hits	298	Target Neighborhood Hits	329	Shared Neighborhood Hits	134
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

DLL3_HUMAN
NC score	0.179578 (rank : 128)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	298	Target Neighborhood Hits	419	Shared Neighborhood Hits	134
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DNER_MOUSE
NC score	0.178957 (rank : 129)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	298	Target Neighborhood Hits	413	Shared Neighborhood Hits	137
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

DLK_HUMAN
NC score	0.178752 (rank : 130)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	298	Target Neighborhood Hits	401	Shared Neighborhood Hits	149
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

UROM_MOUSE
NC score	0.177722 (rank : 131)	θ value	0.00228821 (rank : 79)
Query Neighborhood Hits	298	Target Neighborhood Hits	276	Shared Neighborhood Hits	114
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

DLK_MOUSE
NC score	0.177467 (rank : 132)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	298	Target Neighborhood Hits	374	Shared Neighborhood Hits	137
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

NTNG2_HUMAN
NC score	0.176950 (rank : 133)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	298	Target Neighborhood Hits	276	Shared Neighborhood Hits	121
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TENA_HUMAN
NC score	0.176919 (rank : 134)	θ value	0.00869519 (rank : 90)
Query Neighborhood Hits	298	Target Neighborhood Hits	631	Shared Neighborhood Hits	157
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

FBLN1_HUMAN
NC score	0.176367 (rank : 135)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	298	Target Neighborhood Hits	324	Shared Neighborhood Hits	125
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

UROM_HUMAN
NC score	0.175796 (rank : 136)	θ value	0.00298849 (rank : 80)
Query Neighborhood Hits	298	Target Neighborhood Hits	284	Shared Neighborhood Hits	116
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

DLL3_MOUSE
NC score	0.175459 (rank : 137)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	298	Target Neighborhood Hits	399	Shared Neighborhood Hits	135
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

NAGPA_MOUSE
NC score	0.175397 (rank : 138)	θ value	2.36792 (rank : 224)
Query Neighborhood Hits	298	Target Neighborhood Hits	308	Shared Neighborhood Hits	128
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NTNG1_HUMAN
NC score	0.174995 (rank : 139)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	298	Target Neighborhood Hits	247	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

TRBM_MOUSE
NC score	0.174418 (rank : 140)	θ value	1.38821 (rank : 204)
Query Neighborhood Hits	298	Target Neighborhood Hits	361	Shared Neighborhood Hits	134
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

MATN2_HUMAN
NC score	0.174002 (rank : 141)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	298	Target Neighborhood Hits	365	Shared Neighborhood Hits	129
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
NC score	0.172743 (rank : 142)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	298	Target Neighborhood Hits	356	Shared Neighborhood Hits	131
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

C1QR1_HUMAN
NC score	0.171659 (rank : 143)	θ value	0.0961366 (rank : 125)
Query Neighborhood Hits	298	Target Neighborhood Hits	493	Shared Neighborhood Hits	127
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

NET2_HUMAN
NC score	0.171493 (rank : 144)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	298	Target Neighborhood Hits	194	Shared Neighborhood Hits	102
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NTNG1_MOUSE
NC score	0.171201 (rank : 145)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	298	Target Neighborhood Hits	246	Shared Neighborhood Hits	116
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_MOUSE
NC score	0.169670 (rank : 146)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	298	Target Neighborhood Hits	276	Shared Neighborhood Hits	120
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

FBLN5_MOUSE
NC score	0.168695 (rank : 147)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	298	Target Neighborhood Hits	317	Shared Neighborhood Hits	131
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

NET2_MOUSE
NC score	0.168661 (rank : 148)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	298	Target Neighborhood Hits	193	Shared Neighborhood Hits	102
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

TENA_MOUSE
NC score	0.168592 (rank : 149)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	298	Target Neighborhood Hits	596	Shared Neighborhood Hits	149
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TRBM_HUMAN
NC score	0.167805 (rank : 150)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	298	Target Neighborhood Hits	339	Shared Neighborhood Hits	123
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NET4_MOUSE
NC score	0.167497 (rank : 151)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	298	Target Neighborhood Hits	180	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NET4_HUMAN
NC score	0.166893 (rank : 152)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	298	Target Neighborhood Hits	191	Shared Neighborhood Hits	102
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NID2_HUMAN
NC score	0.165529 (rank : 153)	θ value	0.00869519 (rank : 89)
Query Neighborhood Hits	298	Target Neighborhood Hits	456	Shared Neighborhood Hits	128
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

TNR16_HUMAN
NC score	0.165426 (rank : 154)	θ value	0.0431538 (rank : 113)
Query Neighborhood Hits	298	Target Neighborhood Hits	183	Shared Neighborhood Hits	87
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

FBLN5_HUMAN
NC score	0.164621 (rank : 155)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	298	Target Neighborhood Hits	329	Shared Neighborhood Hits	135
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

KR101_HUMAN
NC score	0.164583 (rank : 156)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	298	Target Neighborhood Hits	261	Shared Neighborhood Hits	107
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

SSPO_MOUSE
NC score	0.164514 (rank : 157)	θ value	1.81305 (rank : 213)
Query Neighborhood Hits	298	Target Neighborhood Hits	800	Shared Neighborhood Hits	187
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

KR10B_HUMAN
NC score	0.164189 (rank : 158)	θ value	0.0252991 (rank : 104)
Query Neighborhood Hits	298	Target Neighborhood Hits	269	Shared Neighborhood Hits	109
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

C1QR1_MOUSE
NC score	0.161969 (rank : 159)	θ value	0.365318 (rank : 156)
Query Neighborhood Hits	298	Target Neighborhood Hits	342	Shared Neighborhood Hits	125
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

KRA45_HUMAN
NC score	0.160348 (rank : 160)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	298	Target Neighborhood Hits	194	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KR108_HUMAN
NC score	0.160292 (rank : 161)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	298	Target Neighborhood Hits	226	Shared Neighborhood Hits	102
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

TNR16_MOUSE
NC score	0.158111 (rank : 162)	θ value	0.0736092 (rank : 124)
Query Neighborhood Hits	298	Target Neighborhood Hits	178	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

ATRN_MOUSE
NC score	0.158043 (rank : 163)	θ value	6.88961 (rank : 273)
Query Neighborhood Hits	298	Target Neighborhood Hits	519	Shared Neighborhood Hits	137
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

KRA47_HUMAN
NC score	0.156196 (rank : 164)	θ value	2.36792 (rank : 221)
Query Neighborhood Hits	298	Target Neighborhood Hits	204	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KR105_HUMAN
NC score	0.155922 (rank : 165)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	298	Target Neighborhood Hits	271	Shared Neighborhood Hits	113
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

TNR25_HUMAN
NC score	0.155910 (rank : 166)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	298	Target Neighborhood Hits	172	Shared Neighborhood Hits	85
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

CUBN_HUMAN
NC score	0.155463 (rank : 167)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	298	Target Neighborhood Hits	482	Shared Neighborhood Hits	133
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

VWF_HUMAN
NC score	0.155318 (rank : 168)	θ value	0.125558 (rank : 135)
Query Neighborhood Hits	298	Target Neighborhood Hits	396	Shared Neighborhood Hits	139
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FBLN4_MOUSE
NC score	0.155315 (rank : 169)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	298	Target Neighborhood Hits	270	Shared Neighborhood Hits	108
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN4_HUMAN
NC score	0.154877 (rank : 170)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	298	Target Neighborhood Hits	278	Shared Neighborhood Hits	111
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

LRP1_HUMAN
NC score	0.154577 (rank : 171)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	298	Target Neighborhood Hits	617	Shared Neighborhood Hits	166
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

KRA93_HUMAN
NC score	0.154196 (rank : 172)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	298	Target Neighborhood Hits	203	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

VWF_MOUSE
NC score	0.153817 (rank : 173)	θ value	0.0113563 (rank : 95)
Query Neighborhood Hits	298	Target Neighborhood Hits	381	Shared Neighborhood Hits	139
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CUBN_MOUSE
NC score	0.153083 (rank : 174)	θ value	5.27518 (rank : 260)
Query Neighborhood Hits	298	Target Neighborhood Hits	477	Shared Neighborhood Hits	139
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

PGBM_MOUSE
NC score	0.151700 (rank : 175)	θ value	0.0330416 (rank : 107)
Query Neighborhood Hits	298	Target Neighborhood Hits	1073	Shared Neighborhood Hits	175
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KRA92_HUMAN
NC score	0.150903 (rank : 176)	θ value	5.27518 (rank : 262)
Query Neighborhood Hits	298	Target Neighborhood Hits	198	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

GRN_HUMAN
NC score	0.150416 (rank : 177)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	298	Target Neighborhood Hits	268	Shared Neighborhood Hits	116
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

NID2_MOUSE
NC score	0.149919 (rank : 178)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	298	Target Neighborhood Hits	338	Shared Neighborhood Hits	117
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NET1_HUMAN
NC score	0.149197 (rank : 179)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	298	Target Neighborhood Hits	149	Shared Neighborhood Hits	78
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

LRP1B_HUMAN
NC score	0.149013 (rank : 180)	θ value	1.06291 (rank : 190)
Query Neighborhood Hits	298	Target Neighborhood Hits	602	Shared Neighborhood Hits	160
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

NET1_MOUSE
NC score	0.148857 (rank : 181)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	298	Target Neighborhood Hits	151	Shared Neighborhood Hits	80
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

ATRN_HUMAN
NC score	0.148188 (rank : 182)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	298	Target Neighborhood Hits	525	Shared Neighborhood Hits	134
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

KRA98_HUMAN
NC score	0.147915 (rank : 183)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	298	Target Neighborhood Hits	185	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

GRN_MOUSE
NC score	0.147477 (rank : 184)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	298	Target Neighborhood Hits	248	Shared Neighborhood Hits	106
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

LRP1B_MOUSE
NC score	0.146941 (rank : 185)	θ value	1.81305 (rank : 209)
Query Neighborhood Hits	298	Target Neighborhood Hits	606	Shared Neighborhood Hits	155
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBLN3_HUMAN
NC score	0.146813 (rank : 186)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	298	Target Neighborhood Hits	293	Shared Neighborhood Hits	121
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

LRP2_HUMAN
NC score	0.146415 (rank : 187)	θ value	0.813845 (rank : 179)
Query Neighborhood Hits	298	Target Neighborhood Hits	573	Shared Neighborhood Hits	159
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

NID1_MOUSE
NC score	0.145344 (rank : 188)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	298	Target Neighborhood Hits	335	Shared Neighborhood Hits	120
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PGBM_HUMAN
NC score	0.144649 (rank : 189)	θ value	0.00665767 (rank : 85)
Query Neighborhood Hits	298	Target Neighborhood Hits	1113	Shared Neighborhood Hits	167
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NID1_HUMAN
NC score	0.143875 (rank : 190)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	298	Target Neighborhood Hits	329	Shared Neighborhood Hits	120
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

KR102_HUMAN
NC score	0.143396 (rank : 191)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	298	Target Neighborhood Hits	264	Shared Neighborhood Hits	110
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

PROS_HUMAN
NC score	0.142504 (rank : 192)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	298	Target Neighborhood Hits	340	Shared Neighborhood Hits	125
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

EGF_MOUSE
NC score	0.141850 (rank : 193)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	298	Target Neighborhood Hits	358	Shared Neighborhood Hits	128
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

PROS_MOUSE
NC score	0.141797 (rank : 194)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	298	Target Neighborhood Hits	330	Shared Neighborhood Hits	120
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FBLN3_MOUSE
NC score	0.141426 (rank : 195)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	298	Target Neighborhood Hits	279	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

BMPER_MOUSE
NC score	0.141043 (rank : 196)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	298	Target Neighborhood Hits	194	Shared Neighborhood Hits	96
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

EGF_HUMAN
NC score	0.140570 (rank : 197)	θ value	0.0961366 (rank : 126)
Query Neighborhood Hits	298	Target Neighborhood Hits	343	Shared Neighborhood Hits	124
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

NFX1_HUMAN
NC score	0.139250 (rank : 198)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	298	Target Neighborhood Hits	405	Shared Neighborhood Hits	116
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

GAS6_HUMAN
NC score	0.138569 (rank : 199)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	298	Target Neighborhood Hits	348	Shared Neighborhood Hits	124
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

KR109_HUMAN
NC score	0.138249 (rank : 200)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	298	Target Neighborhood Hits	226	Shared Neighborhood Hits	92
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

TECTA_MOUSE
NC score	0.137668 (rank : 201)	θ value	0.000602161 (rank : 63)
Query Neighborhood Hits	298	Target Neighborhood Hits	244	Shared Neighborhood Hits	106
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

GAS6_MOUSE
NC score	0.137522 (rank : 202)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	298	Target Neighborhood Hits	343	Shared Neighborhood Hits	126
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

KRA13_HUMAN
NC score	0.136738 (rank : 203)	θ value	1.38821 (rank : 200)
Query Neighborhood Hits	298	Target Neighborhood Hits	144	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

COMP_HUMAN
NC score	0.135039 (rank : 204)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	298	Target Neighborhood Hits	258	Shared Neighborhood Hits	119
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

ITB5_MOUSE
NC score	0.134699 (rank : 205)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	298	Target Neighborhood Hits	329	Shared Neighborhood Hits	142
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

COMP_MOUSE
NC score	0.134061 (rank : 206)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	298	Target Neighborhood Hits	290	Shared Neighborhood Hits	129
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

KR10C_HUMAN
NC score	0.133829 (rank : 207)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	298	Target Neighborhood Hits	219	Shared Neighborhood Hits	101
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

BMPER_HUMAN
NC score	0.133337 (rank : 208)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	298	Target Neighborhood Hits	175	Shared Neighborhood Hits	89
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

LCE1C_HUMAN
NC score	0.132606 (rank : 209)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	298	Target Neighborhood Hits	65	Shared Neighborhood Hits	42
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

MATN3_HUMAN
NC score	0.132504 (rank : 210)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	298	Target Neighborhood Hits	268	Shared Neighborhood Hits	96
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

KRA94_HUMAN
NC score	0.132060 (rank : 211)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	298	Target Neighborhood Hits	204	Shared Neighborhood Hits	101
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA11_HUMAN
NC score	0.132001 (rank : 212)	θ value	1.81305 (rank : 208)
Query Neighborhood Hits	298	Target Neighborhood Hits	155	Shared Neighborhood Hits	66
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

ITB2_MOUSE
NC score	0.131709 (rank : 213)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	298	Target Neighborhood Hits	326	Shared Neighborhood Hits	141
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

EGFL7_HUMAN
NC score	0.131022 (rank : 214)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	298	Target Neighborhood Hits	325	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

MUC5B_HUMAN
NC score	0.130588 (rank : 215)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	298	Target Neighborhood Hits	1020	Shared Neighborhood Hits	150
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

ITB5_HUMAN
NC score	0.130233 (rank : 216)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	298	Target Neighborhood Hits	310	Shared Neighborhood Hits	129
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB7_HUMAN
NC score	0.129667 (rank : 217)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	298	Target Neighborhood Hits	290	Shared Neighborhood Hits	129
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

KRA44_HUMAN
NC score	0.129395 (rank : 218)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	298	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

TSP4_MOUSE
NC score	0.128757 (rank : 219)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	298	Target Neighborhood Hits	276	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

TECTA_HUMAN
NC score	0.128405 (rank : 220)	θ value	0.00102713 (rank : 66)
Query Neighborhood Hits	298	Target Neighborhood Hits	239	Shared Neighborhood Hits	100
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

ITB7_MOUSE
NC score	0.128059 (rank : 221)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	298	Target Neighborhood Hits	277	Shared Neighborhood Hits	124
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

TNR14_HUMAN
NC score	0.127557 (rank : 222)	θ value	5.27518 (rank : 268)
Query Neighborhood Hits	298	Target Neighborhood Hits	149	Shared Neighborhood Hits	90
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ITB3_HUMAN
NC score	0.127556 (rank : 223)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	298	Target Neighborhood Hits	325	Shared Neighborhood Hits	140
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

EGFL7_MOUSE
NC score	0.127401 (rank : 224)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	298	Target Neighborhood Hits	287	Shared Neighborhood Hits	106
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

TNR23_MOUSE
NC score	0.127241 (rank : 225)	θ value	2.36792 (rank : 227)
Query Neighborhood Hits	298	Target Neighborhood Hits	114	Shared Neighborhood Hits	74
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

SUSD1_HUMAN
NC score	0.127043 (rank : 226)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	298	Target Neighborhood Hits	285	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

LDLR_HUMAN
NC score	0.126997 (rank : 227)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	298	Target Neighborhood Hits	375	Shared Neighborhood Hits	133
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

HHIP_HUMAN
NC score	0.126671 (rank : 228)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	298	Target Neighborhood Hits	249	Shared Neighborhood Hits	113
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KRA99_HUMAN
NC score	0.126329 (rank : 229)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	298	Target Neighborhood Hits	173	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

EMR1_HUMAN
NC score	0.126326 (rank : 230)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	298	Target Neighborhood Hits	382	Shared Neighborhood Hits	114
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

KR412_HUMAN
NC score	0.125879 (rank : 231)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	298	Target Neighborhood Hits	178	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

LCE2A_HUMAN
NC score	0.124912 (rank : 232)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	298	Target Neighborhood Hits	50	Shared Neighborhood Hits	24
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

TSP1_HUMAN
NC score	0.124652 (rank : 233)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	298	Target Neighborhood Hits	389	Shared Neighborhood Hits	142
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP4_HUMAN
NC score	0.124609 (rank : 234)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	298	Target Neighborhood Hits	277	Shared Neighborhood Hits	112
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

ITB3_MOUSE
NC score	0.124545 (rank : 235)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	298	Target Neighborhood Hits	319	Shared Neighborhood Hits	136
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB6_MOUSE
NC score	0.124206 (rank : 236)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	298	Target Neighborhood Hits	341	Shared Neighborhood Hits	132
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

TSP1_MOUSE
NC score	0.123875 (rank : 237)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	298	Target Neighborhood Hits	396	Shared Neighborhood Hits	144
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TNR1A_MOUSE
NC score	0.123868 (rank : 238)	θ value	0.00134147 (rank : 71)
Query Neighborhood Hits	298	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR9_MOUSE
NC score	0.123615 (rank : 239)	θ value	3.0926 (rank : 242)
Query Neighborhood Hits	298	Target Neighborhood Hits	137	Shared Neighborhood Hits	72
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR26_MOUSE
NC score	0.123516 (rank : 240)	θ value	0.00869519 (rank : 91)
Query Neighborhood Hits	298	Target Neighborhood Hits	106	Shared Neighborhood Hits	63
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

LCE1B_HUMAN
NC score	0.123060 (rank : 241)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	298	Target Neighborhood Hits	58	Shared Neighborhood Hits	38
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

MATN4_MOUSE
NC score	0.122903 (rank : 242)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	298	Target Neighborhood Hits	277	Shared Neighborhood Hits	107
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

LDLR_MOUSE
NC score	0.122885 (rank : 243)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	298	Target Neighborhood Hits	382	Shared Neighborhood Hits	127
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

HHIP_MOUSE
NC score	0.122726 (rank : 244)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	298	Target Neighborhood Hits	219	Shared Neighborhood Hits	104
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

MATN3_MOUSE
NC score	0.122124 (rank : 245)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	298	Target Neighborhood Hits	261	Shared Neighborhood Hits	100
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

TSP3_MOUSE
NC score	0.121234 (rank : 246)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	298	Target Neighborhood Hits	247	Shared Neighborhood Hits	110
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

MT3_MOUSE
NC score	0.121021 (rank : 247)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	298	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

VLDLR_HUMAN
NC score	0.120633 (rank : 248)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	298	Target Neighborhood Hits	383	Shared Neighborhood Hits	122
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

MATN4_HUMAN
NC score	0.119645 (rank : 249)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	298	Target Neighborhood Hits	287	Shared Neighborhood Hits	112
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

ZAN_HUMAN
NC score	0.119556 (rank : 250)	θ value	2.36792 (rank : 229)
Query Neighborhood Hits	298	Target Neighborhood Hits	679	Shared Neighborhood Hits	137
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

VLDLR_MOUSE
NC score	0.119191 (rank : 251)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	298	Target Neighborhood Hits	360	Shared Neighborhood Hits	116
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

TSP3_HUMAN
NC score	0.119177 (rank : 252)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	298	Target Neighborhood Hits	250	Shared Neighborhood Hits	104
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

LCE1F_HUMAN
NC score	0.119140 (rank : 253)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	298	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

CD248_HUMAN
NC score	0.118418 (rank : 254)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	298	Target Neighborhood Hits	679	Shared Neighborhood Hits	116
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

SLIT1_HUMAN
NC score	0.118373 (rank : 255)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	298	Target Neighborhood Hits	700	Shared Neighborhood Hits	141
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
NC score	0.118356 (rank : 256)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	298	Target Neighborhood Hits	715	Shared Neighborhood Hits	143
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

LRP8_MOUSE
NC score	0.118220 (rank : 257)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	298	Target Neighborhood Hits	385	Shared Neighborhood Hits	121
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

ITB6_HUMAN
NC score	0.118151 (rank : 258)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	298	Target Neighborhood Hits	318	Shared Neighborhood Hits	134
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

KR414_HUMAN
NC score	0.118083 (rank : 259)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	298	Target Neighborhood Hits	199	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

ITB2_HUMAN
NC score	0.117410 (rank : 260)	θ value	2.36792 (rank : 218)
Query Neighborhood Hits	298	Target Neighborhood Hits	282	Shared Neighborhood Hits	129
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB1_MOUSE
NC score	0.116887 (rank : 261)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	298	Target Neighborhood Hits	283	Shared Neighborhood Hits	125
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_HUMAN
NC score	0.116829 (rank : 262)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	298	Target Neighborhood Hits	298	Shared Neighborhood Hits	130
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

EGFL8_HUMAN
NC score	0.116542 (rank : 263)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	298	Target Neighborhood Hits	270	Shared Neighborhood Hits	92
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

CD248_MOUSE
NC score	0.115560 (rank : 264)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	298	Target Neighborhood Hits	578	Shared Neighborhood Hits	107
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

HMCN1_HUMAN
NC score	0.115187 (rank : 265)	θ value	1.81305 (rank : 207)
Query Neighborhood Hits	298	Target Neighborhood Hits	983	Shared Neighborhood Hits	150
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

CD97_HUMAN
NC score	0.114953 (rank : 266)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	298	Target Neighborhood Hits	353	Shared Neighborhood Hits	109
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR2_HUMAN
NC score	0.114739 (rank : 267)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	298	Target Neighborhood Hits	345	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

SLIT2_HUMAN
NC score	0.113875 (rank : 268)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	298	Target Neighborhood Hits	708	Shared Neighborhood Hits	143
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

EMR1_MOUSE
NC score	0.113720 (rank : 269)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	298	Target Neighborhood Hits	349	Shared Neighborhood Hits	102
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

TNR4_MOUSE
NC score	0.113132 (rank : 270)	θ value	5.27518 (rank : 269)
Query Neighborhood Hits	298	Target Neighborhood Hits	137	Shared Neighborhood Hits	77
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

SLIT3_HUMAN
NC score	0.113113 (rank : 271)	θ value	0.0961366 (rank : 130)
Query Neighborhood Hits	298	Target Neighborhood Hits	682	Shared Neighborhood Hits	137
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

LCE2C_HUMAN
NC score	0.112981 (rank : 272)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	298	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

ERBB3_HUMAN
NC score	0.112880 (rank : 273)	θ value	9.59137e-10 (rank : 20)
Query Neighborhood Hits	298	Target Neighborhood Hits	918	Shared Neighborhood Hits	75
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

LCE1E_HUMAN
NC score	0.112651 (rank : 274)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	298	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

ZNFX1_HUMAN
NC score	0.112551 (rank : 275)	θ value	5.27518 (rank : 272)
Query Neighborhood Hits	298	Target Neighborhood Hits	308	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

KR10A_HUMAN
NC score	0.112519 (rank : 276)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	298	Target Neighborhood Hits	232	Shared Neighborhood Hits	97
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

SLIT3_MOUSE
NC score	0.112443 (rank : 277)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	298	Target Neighborhood Hits	700	Shared Neighborhood Hits	145
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

EGFL8_MOUSE
NC score	0.112307 (rank : 278)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	298	Target Neighborhood Hits	266	Shared Neighborhood Hits	91
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

SLIT2_MOUSE
NC score	0.111906 (rank : 279)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	298	Target Neighborhood Hits	684	Shared Neighborhood Hits	134
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

LCE2D_HUMAN
NC score	0.111483 (rank : 280)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	298	Target Neighborhood Hits	50	Shared Neighborhood Hits	22
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

ERBB3_MOUSE
NC score	0.111366 (rank : 281)	θ value	6.21693e-09 (rank : 28)
Query Neighborhood Hits	298	Target Neighborhood Hits	898	Shared Neighborhood Hits	70
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ITB4_HUMAN
NC score	0.111167 (rank : 282)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	298	Target Neighborhood Hits	458	Shared Neighborhood Hits	132
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

LRP4_HUMAN
NC score	0.110499 (rank : 283)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	298	Target Neighborhood Hits	355	Shared Neighborhood Hits	111
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LCE2B_HUMAN
NC score	0.110066 (rank : 284)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	298	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

KRA15_HUMAN
NC score	0.110014 (rank : 285)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	298	Target Neighborhood Hits	126	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

TNR1B_HUMAN
NC score	0.108643 (rank : 286)	θ value	0.0431538 (rank : 114)
Query Neighborhood Hits	298	Target Neighborhood Hits	127	Shared Neighborhood Hits	64
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

MT3_HUMAN
NC score	0.108427 (rank : 287)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	298	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

LRP4_MOUSE
NC score	0.108363 (rank : 288)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	298	Target Neighborhood Hits	351	Shared Neighborhood Hits	111
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

KR103_HUMAN
NC score	0.108250 (rank : 289)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	298	Target Neighborhood Hits	212	Shared Neighborhood Hits	89
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

TENR_HUMAN
NC score	0.108247 (rank : 290)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	298	Target Neighborhood Hits	526	Shared Neighborhood Hits	142
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

LRP8_HUMAN
NC score	0.108239 (rank : 291)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	298	Target Neighborhood Hits	346	Shared Neighborhood Hits	109
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

EDIL3_MOUSE
NC score	0.107874 (rank : 292)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	298	Target Neighborhood Hits	317	Shared Neighborhood Hits	118
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

TNR9_HUMAN
NC score	0.107469 (rank : 293)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	298	Target Neighborhood Hits	166	Shared Neighborhood Hits	75
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR1B_MOUSE
NC score	0.106878 (rank : 294)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	298	Target Neighborhood Hits	123	Shared Neighborhood Hits	56
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR5_MOUSE
NC score	0.106746 (rank : 295)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	298	Target Neighborhood Hits	131	Shared Neighborhood Hits	77
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

ZNFX1_MOUSE
NC score	0.106037 (rank : 296)	θ value	0.813845 (rank : 185)
Query Neighborhood Hits	298	Target Neighborhood Hits	407	Shared Neighborhood Hits	82
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

KR410_HUMAN
NC score	0.105740 (rank : 297)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	298	Target Neighborhood Hits	156	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

TSP2_MOUSE
NC score	0.104925 (rank : 298)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	298	Target Neighborhood Hits	352	Shared Neighborhood Hits	128
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

LCE1D_HUMAN
NC score	0.104599 (rank : 299)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	298	Target Neighborhood Hits	44	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

ITB8_HUMAN
NC score	0.104394 (rank : 300)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	298	Target Neighborhood Hits	280	Shared Neighborhood Hits	118
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

TNR22_MOUSE
NC score	0.104128 (rank : 301)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	298	Target Neighborhood Hits	97	Shared Neighborhood Hits	60
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR7_HUMAN
NC score	0.103719 (rank : 302)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	298	Target Neighborhood Hits	120	Shared Neighborhood Hits	71
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

SORL_MOUSE
NC score	0.103572 (rank : 303)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	298	Target Neighborhood Hits	439	Shared Neighborhood Hits	127
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TENR_MOUSE
NC score	0.103517 (rank : 304)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	298	Target Neighborhood Hits	531	Shared Neighborhood Hits	138
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

LCE1A_HUMAN
NC score	0.103109 (rank : 305)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	298	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

ERBB4_HUMAN
NC score	0.102479 (rank : 306)	θ value	1.63604e-09 (rank : 21)
Query Neighborhood Hits	298	Target Neighborhood Hits	910	Shared Neighborhood Hits	74
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

TNR3_HUMAN
NC score	0.102150 (rank : 307)	θ value	1.06291 (rank : 191)
Query Neighborhood Hits	298	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR1A_HUMAN
NC score	0.102111 (rank : 308)	θ value	0.813845 (rank : 181)
Query Neighborhood Hits	298	Target Neighborhood Hits	121	Shared Neighborhood Hits	45
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TIE1_HUMAN
NC score	0.101327 (rank : 309)	θ value	0.0330416 (rank : 109)
Query Neighborhood Hits	298	Target Neighborhood Hits	1241	Shared Neighborhood Hits	146
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TSP2_HUMAN
NC score	0.101119 (rank : 310)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	298	Target Neighborhood Hits	359	Shared Neighborhood Hits	130
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

LYAM3_MOUSE
NC score	0.101110 (rank : 311)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	298	Target Neighborhood Hits	390	Shared Neighborhood Hits	117
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

EDIL3_HUMAN
NC score	0.100722 (rank : 312)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	298	Target Neighborhood Hits	292	Shared Neighborhood Hits	110
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

TNR4_HUMAN
NC score	0.099811 (rank : 313)	θ value	3.0926 (rank : 241)
Query Neighborhood Hits	298	Target Neighborhood Hits	152	Shared Neighborhood Hits	71
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

LCE3A_HUMAN
NC score	0.099629 (rank : 314)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	298	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

SORL_HUMAN
NC score	0.098742 (rank : 315)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	298	Target Neighborhood Hits	440	Shared Neighborhood Hits	120
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

ERBB2_HUMAN
NC score	0.098693 (rank : 316)	θ value	3.64472e-09 (rank : 26)
Query Neighborhood Hits	298	Target Neighborhood Hits	1073	Shared Neighborhood Hits	60
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
NC score	0.098561 (rank : 317)	θ value	3.64472e-09 (rank : 27)
Query Neighborhood Hits	298	Target Neighborhood Hits	918	Shared Neighborhood Hits	60
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

LYAM2_MOUSE
NC score	0.098134 (rank : 318)	θ value	0.0961366 (rank : 128)
Query Neighborhood Hits	298	Target Neighborhood Hits	420	Shared Neighborhood Hits	126
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

EGFR_MOUSE
NC score	0.097275 (rank : 319)	θ value	1.06045e-08 (rank : 30)
Query Neighborhood Hits	298	Target Neighborhood Hits	927	Shared Neighborhood Hits	85
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

TIE1_MOUSE
NC score	0.096648 (rank : 320)	θ value	5.27518 (rank : 267)
Query Neighborhood Hits	298	Target Neighborhood Hits	1266	Shared Neighborhood Hits	144
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

EGFR_HUMAN
NC score	0.096222 (rank : 321)	θ value	3.64472e-09 (rank : 25)
Query Neighborhood Hits	298	Target Neighborhood Hits	939	Shared Neighborhood Hits	79
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

TNR8_HUMAN
NC score	0.095649 (rank : 322)	θ value	1.38821 (rank : 203)
Query Neighborhood Hits	298	Target Neighborhood Hits	198	Shared Neighborhood Hits	68
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TIE2_MOUSE
NC score	0.095568 (rank : 323)	θ value	0.0193708 (rank : 101)
Query Neighborhood Hits	298	Target Neighborhood Hits	1204	Shared Neighborhood Hits	140
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

MBTP1_HUMAN
NC score	0.095483 (rank : 324)	θ value	0.0736092 (rank : 122)
Query Neighborhood Hits	298	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

MKS3_MOUSE
NC score	0.095275 (rank : 325)	θ value	0.0961366 (rank : 129)
Query Neighborhood Hits	298	Target Neighborhood Hits	89	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

TR11B_HUMAN
NC score	0.094760 (rank : 326)	θ value	0.163984 (rank : 143)
Query Neighborhood Hits	298	Target Neighborhood Hits	92	Shared Neighborhood Hits	54
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

LYAM2_HUMAN
NC score	0.094137 (rank : 327)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	298	Target Neighborhood Hits	394	Shared Neighborhood Hits	122
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ESM1_HUMAN
NC score	0.093491 (rank : 328)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	298	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

LCE5A_HUMAN
NC score	0.093251 (rank : 329)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	298	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

MT4_MOUSE
NC score	0.092802 (rank : 330)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	298	Target Neighborhood Hits	102	Shared Neighborhood Hits	44
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

TNR6B_HUMAN
NC score	0.091513 (rank : 331)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	298	Target Neighborhood Hits	103	Shared Neighborhood Hits	63
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

ELTD1_MOUSE
NC score	0.090613 (rank : 332)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	298	Target Neighborhood Hits	288	Shared Neighborhood Hits	81
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

INSRR_HUMAN
NC score	0.090238 (rank : 333)	θ value	6.43352e-06 (rank : 39)
Query Neighborhood Hits	298	Target Neighborhood Hits	950	Shared Neighborhood Hits	92
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

MBTP1_MOUSE
NC score	0.089969 (rank : 334)	θ value	0.21417 (rank : 147)
Query Neighborhood Hits	298	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTZ2, Q6PG67	Gene names	Mbtps1, S1p, Ski1
Domain Architecture
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin isozyme 1) (SKI-1) (Sterol-regulated luminal protease).

TNR6_MOUSE
NC score	0.089604 (rank : 335)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	298	Target Neighborhood Hits	99	Shared Neighborhood Hits	62
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

CD97_MOUSE
NC score	0.089281 (rank : 336)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	298	Target Neighborhood Hits	295	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

INSRR_MOUSE
NC score	0.089137 (rank : 337)	θ value	1.09739e-05 (rank : 40)
Query Neighborhood Hits	298	Target Neighborhood Hits	961	Shared Neighborhood Hits	104
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

MUC2_HUMAN
NC score	0.088389 (rank : 338)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	298	Target Neighborhood Hits	906	Shared Neighborhood Hits	106
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TIE2_HUMAN
NC score	0.087249 (rank : 339)	θ value	3.0926 (rank : 238)
Query Neighborhood Hits	298	Target Neighborhood Hits	1192	Shared Neighborhood Hits	136
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

MT2_MOUSE
NC score	0.087223 (rank : 340)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	298	Target Neighborhood Hits	81	Shared Neighborhood Hits	28
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

IGF1R_MOUSE
NC score	0.087161 (rank : 341)	θ value	9.29e-05 (rank : 48)
Query Neighborhood Hits	298	Target Neighborhood Hits	973	Shared Neighborhood Hits	87
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

TNR5_HUMAN
NC score	0.086361 (rank : 342)	θ value	0.813845 (rank : 182)
Query Neighborhood Hits	298	Target Neighborhood Hits	102	Shared Neighborhood Hits	62
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

LYAM3_HUMAN
NC score	0.085874 (rank : 343)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	298	Target Neighborhood Hits	378	Shared Neighborhood Hits	114
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TENN_MOUSE
NC score	0.085728 (rank : 344)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	298	Target Neighborhood Hits	484	Shared Neighborhood Hits	129
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TNR3_MOUSE
NC score	0.085281 (rank : 345)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	298	Target Neighborhood Hits	113	Shared Neighborhood Hits	65
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

KRA42_HUMAN
NC score	0.085132 (rank : 346)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	298	Target Neighborhood Hits	149	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

IGF1R_HUMAN
NC score	0.084840 (rank : 347)	θ value	2.44474e-05 (rank : 42)
Query Neighborhood Hits	298	Target Neighborhood Hits	977	Shared Neighborhood Hits	87
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

ESM1_MOUSE
NC score	0.084513 (rank : 348)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	298	Target Neighborhood Hits	107	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

TNR11_HUMAN
NC score	0.084490 (rank : 349)	θ value	3.0926 (rank : 240)
Query Neighborhood Hits	298	Target Neighborhood Hits	135	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TR10A_HUMAN
NC score	0.084138 (rank : 350)	θ value	0.0961366 (rank : 131)
Query Neighborhood Hits	298	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

CELR2_HUMAN
NC score	0.083781 (rank : 351)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	298	Target Neighborhood Hits	657	Shared Neighborhood Hits	137
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_MOUSE
NC score	0.083535 (rank : 352)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	298	Target Neighborhood Hits	687	Shared Neighborhood Hits	138
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

PROZ_MOUSE
NC score	0.083242 (rank : 353)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	298	Target Neighborhood Hits	410	Shared Neighborhood Hits	101
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CELR3_HUMAN
NC score	0.082592 (rank : 354)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	298	Target Neighborhood Hits	680	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

MKS3_HUMAN
NC score	0.082073 (rank : 355)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	298	Target Neighborhood Hits	79	Shared Neighborhood Hits	56
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

PROZ_HUMAN
NC score	0.081888 (rank : 356)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	298	Target Neighborhood Hits	422	Shared Neighborhood Hits	107
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CSPG3_MOUSE
NC score	0.081518 (rank : 357)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	298	Target Neighborhood Hits	657	Shared Neighborhood Hits	117
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

INSR_MOUSE
NC score	0.081215 (rank : 358)	θ value	0.00020696 (rank : 54)
Query Neighborhood Hits	298	Target Neighborhood Hits	968	Shared Neighborhood Hits	78
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_HUMAN
NC score	0.080979 (rank : 359)	θ value	0.00102713 (rank : 65)
Query Neighborhood Hits	298	Target Neighborhood Hits	963	Shared Neighborhood Hits	85
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

TNR21_HUMAN
NC score	0.080951 (rank : 360)	θ value	0.365318 (rank : 159)
Query Neighborhood Hits	298	Target Neighborhood Hits	90	Shared Neighborhood Hits	56
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

CELR1_MOUSE
NC score	0.079786 (rank : 361)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	298	Target Neighborhood Hits	617	Shared Neighborhood Hits	135
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR1_HUMAN
NC score	0.079662 (rank : 362)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	298	Target Neighborhood Hits	613	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR2_MOUSE
NC score	0.079577 (rank : 363)	θ value	0.0148317 (rank : 96)
Query Neighborhood Hits	298	Target Neighborhood Hits	584	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CSPG2_MOUSE
NC score	0.079491 (rank : 364)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	298	Target Neighborhood Hits	711	Shared Neighborhood Hits	111
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
NC score	0.079482 (rank : 365)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	298	Target Neighborhood Hits	676	Shared Neighborhood Hits	117
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TDGF1_MOUSE
NC score	0.079215 (rank : 366)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	298	Target Neighborhood Hits	146	Shared Neighborhood Hits	69
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

MT4_HUMAN
NC score	0.078990 (rank : 367)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	298	Target Neighborhood Hits	83	Shared Neighborhood Hits	32
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

TENN_HUMAN
NC score	0.078982 (rank : 368)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	298	Target Neighborhood Hits	453	Shared Neighborhood Hits	123
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TNR7_MOUSE
NC score	0.078670 (rank : 369)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	298	Target Neighborhood Hits	112	Shared Neighborhood Hits	56
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

MT1X_HUMAN
NC score	0.078531 (rank : 370)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	298	Target Neighborhood Hits	76	Shared Neighborhood Hits	33
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

TR11B_MOUSE
NC score	0.078389 (rank : 371)	θ value	2.36792 (rank : 228)
Query Neighborhood Hits	298	Target Neighborhood Hits	95	Shared Neighborhood Hits	53
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

CSPG2_HUMAN
NC score	0.078110 (rank : 372)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	298	Target Neighborhood Hits	681	Shared Neighborhood Hits	111
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

MT1A_HUMAN
NC score	0.077873 (rank : 373)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	298	Target Neighborhood Hits	74	Shared Neighborhood Hits	26
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

VEGFC_HUMAN
NC score	0.077665 (rank : 374)	θ value	1.06291 (rank : 193)
Query Neighborhood Hits	298	Target Neighborhood Hits	128	Shared Neighborhood Hits	63
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CFC1_HUMAN
NC score	0.077437 (rank : 375)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	298	Target Neighborhood Hits	148	Shared Neighborhood Hits	66
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

FATH_HUMAN
NC score	0.076679 (rank : 376)	θ value	6.88961 (rank : 278)
Query Neighborhood Hits	298	Target Neighborhood Hits	570	Shared Neighborhood Hits	129
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TNR11_MOUSE
NC score	0.075642 (rank : 377)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	298	Target Neighborhood Hits	121	Shared Neighborhood Hits	66
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

MT1_MOUSE
NC score	0.075068 (rank : 378)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	298	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

TNR6_HUMAN
NC score	0.074952 (rank : 379)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	298	Target Neighborhood Hits	95	Shared Neighborhood Hits	56
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TR10C_HUMAN
NC score	0.073913 (rank : 380)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	298	Target Neighborhood Hits	105	Shared Neighborhood Hits	37
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

CHRD_HUMAN
NC score	0.073768 (rank : 381)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	298	Target Neighborhood Hits	102	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

LYAM1_MOUSE
NC score	0.073733 (rank : 382)	θ value	0.365318 (rank : 157)
Query Neighborhood Hits	298	Target Neighborhood Hits	332	Shared Neighborhood Hits	98
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

TNR8_MOUSE
NC score	0.073232 (rank : 383)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	298	Target Neighborhood Hits	208	Shared Neighborhood Hits	73
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

MT1G_HUMAN
NC score	0.073211 (rank : 384)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	298	Target Neighborhood Hits	63	Shared Neighborhood Hits	25
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

CHRD_MOUSE
NC score	0.072772 (rank : 385)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	298	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

MT1L_HUMAN
NC score	0.071986 (rank : 386)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	298	Target Neighborhood Hits	73	Shared Neighborhood Hits	23
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

TNR19_MOUSE
NC score	0.070417 (rank : 387)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	298	Target Neighborhood Hits	100	Shared Neighborhood Hits	54
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

FREM2_MOUSE
NC score	0.070369 (rank : 388)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	298	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

RECK_HUMAN
NC score	0.070144 (rank : 389)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	298	Target Neighborhood Hits	189	Shared Neighborhood Hits	63
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TNR21_MOUSE
NC score	0.070125 (rank : 390)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	298	Target Neighborhood Hits	108	Shared Neighborhood Hits	59
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

RECK_MOUSE
NC score	0.069745 (rank : 391)	θ value	1.38821 (rank : 202)
Query Neighborhood Hits	298	Target Neighborhood Hits	158	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

FREM2_HUMAN
NC score	0.069537 (rank : 392)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	298	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

KRA24_HUMAN
NC score	0.068883 (rank : 393)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	298	Target Neighborhood Hits	192	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

TR10B_HUMAN
NC score	0.068865 (rank : 394)	θ value	5.27518 (rank : 270)
Query Neighborhood Hits	298	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

MT1H_HUMAN
NC score	0.068610 (rank : 395)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	298	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MFGM_MOUSE
NC score	0.067772 (rank : 396)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	298	Target Neighborhood Hits	233	Shared Neighborhood Hits	92
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

CRAC1_MOUSE
NC score	0.067250 (rank : 397)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	298	Target Neighborhood Hits	112	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

KR413_HUMAN
NC score	0.067241 (rank : 398)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	298	Target Neighborhood Hits	112	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

CRAC1_HUMAN
NC score	0.066829 (rank : 399)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	298	Target Neighborhood Hits	111	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CT127_HUMAN
NC score	0.066658 (rank : 400)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	298	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

LORI_MOUSE
NC score	0.065871 (rank : 401)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	298	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

UROL1_MOUSE
NC score	0.065202 (rank : 402)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	298	Target Neighborhood Hits	235	Shared Neighborhood Hits	70
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

LCE4A_HUMAN
NC score	0.064857 (rank : 403)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	298	Target Neighborhood Hits	26	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

TR10B_MOUSE
NC score	0.064716 (rank : 404)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	298	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR10D_HUMAN
NC score	0.064058 (rank : 405)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	298	Target Neighborhood Hits	62	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TDGF2_HUMAN
NC score	0.063531 (rank : 406)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	298	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

MCSP_MOUSE
NC score	0.063445 (rank : 407)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	298	Target Neighborhood Hits	108	Shared Neighborhood Hits	39
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

TEFF2_MOUSE
NC score	0.063328 (rank : 408)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	298	Target Neighborhood Hits	214	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

CFC1_MOUSE
NC score	0.063288 (rank : 409)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	298	Target Neighborhood Hits	125	Shared Neighborhood Hits	60
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

LYAM1_HUMAN
NC score	0.063173 (rank : 410)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	298	Target Neighborhood Hits	315	Shared Neighborhood Hits	91
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

UROL1_HUMAN
NC score	0.063164 (rank : 411)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	298	Target Neighborhood Hits	213	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

ELTD1_HUMAN
NC score	0.062558 (rank : 412)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	298	Target Neighborhood Hits	269	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

TDGF1_HUMAN
NC score	0.062555 (rank : 413)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	298	Target Neighborhood Hits	132	Shared Neighborhood Hits	55
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

MUC13_MOUSE
NC score	0.062017 (rank : 414)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	298	Target Neighborhood Hits	447	Shared Neighborhood Hits	85
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

TEFF2_HUMAN
NC score	0.061992 (rank : 415)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	298	Target Neighborhood Hits	211	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

VEGFC_MOUSE
NC score	0.061414 (rank : 416)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	298	Target Neighborhood Hits	119	Shared Neighborhood Hits	55
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

FREM3_HUMAN
NC score	0.061247 (rank : 417)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	298	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM3_MOUSE
NC score	0.061179 (rank : 418)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	298	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

TNR19_HUMAN
NC score	0.061138 (rank : 419)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	298	Target Neighborhood Hits	89	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

PCSK9_HUMAN
NC score	0.060343 (rank : 420)	θ value	0.813845 (rank : 180)
Query Neighborhood Hits	298	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBP7, Q5PSM5	Gene names	PCSK9, NARC1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

WFDC3_HUMAN
NC score	0.059816 (rank : 421)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	298	Target Neighborhood Hits	138	Shared Neighborhood Hits	52
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

CSPG4_HUMAN
NC score	0.059808 (rank : 422)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	298	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

TR13B_MOUSE
NC score	0.058257 (rank : 423)	θ value	0.365318 (rank : 160)
Query Neighborhood Hits	298	Target Neighborhood Hits	29	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ET35, Q9DBZ3	Gene names	Tnfrsf13b, Taci
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor).

PERT_HUMAN
NC score	0.057654 (rank : 424)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	298	Target Neighborhood Hits	221	Shared Neighborhood Hits	68
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

CSPG4_MOUSE
NC score	0.057301 (rank : 425)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	298	Target Neighborhood Hits	105	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

MT1B_HUMAN
NC score	0.057236 (rank : 426)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	298	Target Neighborhood Hits	87	Shared Neighborhood Hits	30
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

FST_MOUSE
NC score	0.057162 (rank : 427)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	298	Target Neighborhood Hits	146	Shared Neighborhood Hits	54
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ADA17_HUMAN
NC score	0.056533 (rank : 428)	θ value	0.365318 (rank : 155)
Query Neighborhood Hits	298	Target Neighborhood Hits	223	Shared Neighborhood Hits	76
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ATS17_HUMAN
NC score	0.056429 (rank : 429)	θ value	1.87187e-05 (rank : 41)
Query Neighborhood Hits	298	Target Neighborhood Hits	194	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

FREM1_HUMAN
NC score	0.055345 (rank : 430)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	298	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

HABP2_HUMAN
NC score	0.054656 (rank : 431)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	298	Target Neighborhood Hits	431	Shared Neighborhood Hits	114
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

FREM1_MOUSE
NC score	0.054506 (rank : 432)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	298	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

PERT_MOUSE
NC score	0.053344 (rank : 433)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	298	Target Neighborhood Hits	221	Shared Neighborhood Hits	68
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

NRX1A_HUMAN
NC score	0.053267 (rank : 434)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	298	Target Neighborhood Hits	170	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

FST_HUMAN
NC score	0.053017 (rank : 435)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	298	Target Neighborhood Hits	129	Shared Neighborhood Hits	45
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

ADA19_MOUSE
NC score	0.052760 (rank : 436)	θ value	1.81305 (rank : 205)
Query Neighborhood Hits	298	Target Neighborhood Hits	315	Shared Neighborhood Hits	106
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

NRX1A_MOUSE
NC score	0.052740 (rank : 437)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	298	Target Neighborhood Hits	164	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

MT2_HUMAN
NC score	0.052732 (rank : 438)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	298	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

CRDL2_MOUSE
NC score	0.052031 (rank : 439)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	298	Target Neighborhood Hits	81	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

HABP2_MOUSE
NC score	0.051880 (rank : 440)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	298	Target Neighborhood Hits	445	Shared Neighborhood Hits	110
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

CRDL2_HUMAN
NC score	0.051783 (rank : 441)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	298	Target Neighborhood Hits	99	Shared Neighborhood Hits	26
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

MT1F_HUMAN
NC score	0.051202 (rank : 442)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	298	Target Neighborhood Hits	73	Shared Neighborhood Hits	24
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1E_HUMAN
NC score	0.051196 (rank : 443)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	298	Target Neighborhood Hits	75	Shared Neighborhood Hits	24
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

ATL3_HUMAN
NC score	0.046636 (rank : 444)	θ value	0.00869519 (rank : 87)
Query Neighborhood Hits	298	Target Neighborhood Hits	414	Shared Neighborhood Hits	36
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

FHL3_MOUSE
NC score	0.046071 (rank : 445)	θ value	0.0252991 (rank : 103)
Query Neighborhood Hits	298	Target Neighborhood Hits	424	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R059, Q9JLP5, Q9WUH3	Gene names	Fhl3
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

EPHA1_MOUSE
NC score	0.045456 (rank : 446)	θ value	1.38821 (rank : 199)
Query Neighborhood Hits	298	Target Neighborhood Hits	958	Shared Neighborhood Hits	74
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

ATS19_MOUSE
NC score	0.045437 (rank : 447)	θ value	0.00665767 (rank : 82)
Query Neighborhood Hits	298	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS19_HUMAN
NC score	0.041611 (rank : 448)	θ value	0.0431538 (rank : 110)
Query Neighborhood Hits	298	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

NOV_HUMAN
NC score	0.040938 (rank : 449)	θ value	3.0926 (rank : 237)
Query Neighborhood Hits	298	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

FA76B_MOUSE
NC score	0.039769 (rank : 450)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	298	Target Neighborhood Hits	181	Shared Neighborhood Hits	14
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

CI094_HUMAN
NC score	0.039191 (rank : 451)	θ value	0.163984 (rank : 137)
Query Neighborhood Hits	298	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

ADA17_MOUSE
NC score	0.038617 (rank : 452)	θ value	5.27518 (rank : 259)
Query Neighborhood Hits	298	Target Neighborhood Hits	201	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

CORIN_MOUSE
NC score	0.036680 (rank : 453)	θ value	3.0926 (rank : 231)
Query Neighborhood Hits	298	Target Neighborhood Hits	451	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ATS16_MOUSE
NC score	0.036550 (rank : 454)	θ value	0.47712 (rank : 161)
Query Neighborhood Hits	298	Target Neighborhood Hits	179	Shared Neighborhood Hits	33
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

FHL3_HUMAN
NC score	0.036415 (rank : 455)	θ value	0.163984 (rank : 139)
Query Neighborhood Hits	298	Target Neighborhood Hits	354	Shared Neighborhood Hits	44
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

ATS16_HUMAN
NC score	0.035440 (rank : 456)	θ value	1.06291 (rank : 186)
Query Neighborhood Hits	298	Target Neighborhood Hits	208	Shared Neighborhood Hits	34
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ADA28_HUMAN
NC score	0.032772 (rank : 457)	θ value	0.279714 (rank : 150)
Query Neighborhood Hits	298	Target Neighborhood Hits	244	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

EDAR_HUMAN
NC score	0.030859 (rank : 458)	θ value	6.88961 (rank : 275)
Query Neighborhood Hits	298	Target Neighborhood Hits	84	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

PHF7_HUMAN
NC score	0.030766 (rank : 459)	θ value	1.38821 (rank : 201)
Query Neighborhood Hits	298	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

KALM_HUMAN
NC score	0.027132 (rank : 460)	θ value	2.36792 (rank : 220)
Query Neighborhood Hits	298	Target Neighborhood Hits	114	Shared Neighborhood Hits	17
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

FA76B_HUMAN
NC score	0.023284 (rank : 461)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	298	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

ZFY_HUMAN
NC score	0.022972 (rank : 462)	θ value	0.0961366 (rank : 132)
Query Neighborhood Hits	298	Target Neighborhood Hits	752	Shared Neighborhood Hits	47
SwissProt Accessions	P08048, Q14021, Q15558, Q96TF3	Gene names	ZFY
Domain Architecture
Description	Zinc finger Y-chromosomal protein.

ZN221_HUMAN
NC score	0.022916 (rank : 463)	θ value	0.00869519 (rank : 92)
Query Neighborhood Hits	298	Target Neighborhood Hits	784	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UK13, Q9P1U8	Gene names	ZNF221
Domain Architecture
Description	Zinc finger protein 221.

ZFX_MOUSE
NC score	0.022521 (rank : 464)	θ value	0.125558 (rank : 136)
Query Neighborhood Hits	298	Target Neighborhood Hits	748	Shared Neighborhood Hits	46
SwissProt Accessions	P17012, P17011	Gene names	Zfx
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZFX_HUMAN
NC score	0.022421 (rank : 465)	θ value	0.163984 (rank : 145)
Query Neighborhood Hits	298	Target Neighborhood Hits	751	Shared Neighborhood Hits	46
SwissProt Accessions	P17010, O43668, Q8WYJ8	Gene names	ZFX
Domain Architecture
Description	Zinc finger X-chromosomal protein.

ZFA_MOUSE
NC score	0.022220 (rank : 466)	θ value	0.21417 (rank : 149)
Query Neighborhood Hits	298	Target Neighborhood Hits	746	Shared Neighborhood Hits	45
SwissProt Accessions	P23607	Gene names	Zfa
Domain Architecture
Description	Zinc finger autosomal protein.

ZNF45_HUMAN
NC score	0.021866 (rank : 467)	θ value	0.62314 (rank : 177)
Query Neighborhood Hits	298	Target Neighborhood Hits	773	Shared Neighborhood Hits	68
SwissProt Accessions	Q02386, P78472, Q9P1U9	Gene names	ZNF45
Domain Architecture
Description	Zinc finger protein 45 (BRC1744).

ZFY2_MOUSE
NC score	0.021831 (rank : 468)	θ value	1.81305 (rank : 215)
Query Neighborhood Hits	298	Target Neighborhood Hits	795	Shared Neighborhood Hits	47
SwissProt Accessions	P20662	Gene names	Zfy2, Zfy-2
Domain Architecture
Description	Zinc finger Y-chromosomal protein 2.

ZFY1_MOUSE
NC score	0.021583 (rank : 469)	θ value	2.36792 (rank : 230)
Query Neighborhood Hits	298	Target Neighborhood Hits	790	Shared Neighborhood Hits	45
SwissProt Accessions	P10925	Gene names	Zfy1, Zfy-1
Domain Architecture
Description	Zinc finger Y-chromosomal protein 1.

FAM5B_MOUSE
NC score	0.021524 (rank : 470)	θ value	6.88961 (rank : 277)
Query Neighborhood Hits	298	Target Neighborhood Hits	51	Shared Neighborhood Hits	21
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

MYRIP_MOUSE
NC score	0.021519 (rank : 471)	θ value	0.62314 (rank : 172)
Query Neighborhood Hits	298	Target Neighborhood Hits	207	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

ZN711_HUMAN
NC score	0.021513 (rank : 472)	θ value	1.06291 (rank : 196)
Query Neighborhood Hits	298	Target Neighborhood Hits	751	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y462, Q6NX42, Q9Y4J6	Gene names	ZNF711, CMPX1, ZNF6
Domain Architecture
Description	Zinc finger protein 711 (Zinc finger protein 6).

ZN319_HUMAN
NC score	0.021284 (rank : 473)	θ value	0.00134147 (rank : 72)
Query Neighborhood Hits	298	Target Neighborhood Hits	772	Shared Neighborhood Hits	56
SwissProt Accessions	Q9P2F9	Gene names	ZNF319, KIAA1388
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

ZN441_HUMAN
NC score	0.021106 (rank : 474)	θ value	0.813845 (rank : 184)
Query Neighborhood Hits	298	Target Neighborhood Hits	754	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N8Z8	Gene names	ZNF441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 441.

ZN319_MOUSE
NC score	0.020967 (rank : 475)	θ value	0.00102713 (rank : 67)
Query Neighborhood Hits	298	Target Neighborhood Hits	762	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ERR8	Gene names	Znf319, Zfp319
Domain Architecture	No domain graphic available
Description	Zinc finger protein 319.

RNF37_MOUSE
NC score	0.020939 (rank : 476)	θ value	2.36792 (rank : 226)
Query Neighborhood Hits	298	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

ZN227_HUMAN
NC score	0.019846 (rank : 477)	θ value	0.47712 (rank : 167)
Query Neighborhood Hits	298	Target Neighborhood Hits	781	Shared Neighborhood Hits	61
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

ZNF44_HUMAN
NC score	0.019754 (rank : 478)	θ value	0.47712 (rank : 169)
Query Neighborhood Hits	298	Target Neighborhood Hits	757	Shared Neighborhood Hits	54
SwissProt Accessions	P15621, P17018, Q9ULZ7	Gene names	ZNF44, KOX7
Domain Architecture
Description	Zinc finger protein 44 (Zinc finger protein KOX7) (Gonadotropin- inducible transcription repressor 2) (GIOT-2).

FAM5B_HUMAN
NC score	0.019490 (rank : 479)	θ value	6.88961 (rank : 276)
Query Neighborhood Hits	298	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

MYRIP_HUMAN
NC score	0.019330 (rank : 480)	θ value	1.81305 (rank : 211)
Query Neighborhood Hits	298	Target Neighborhood Hits	269	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

ZN709_HUMAN
NC score	0.018915 (rank : 481)	θ value	1.06291 (rank : 195)
Query Neighborhood Hits	298	Target Neighborhood Hits	746	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N972	Gene names	ZNF709
Domain Architecture	No domain graphic available
Description	Zinc finger protein 709.

ZFP28_MOUSE
NC score	0.018852 (rank : 482)	θ value	4.03905 (rank : 257)
Query Neighborhood Hits	298	Target Neighborhood Hits	782	Shared Neighborhood Hits	54
SwissProt Accessions	P10078, Q61776, Q8BT11, Q8C836	Gene names	Zfp28, Mkr5, Zfp-28
Domain Architecture
Description	Zinc finger protein 28 (Zfp-28) (Protein mKR5).

CNBP_MOUSE
NC score	0.018679 (rank : 483)	θ value	4.03905 (rank : 250)
Query Neighborhood Hits	298	Target Neighborhood Hits	215	Shared Neighborhood Hits	24
SwissProt Accessions	P53996, Q80Y06, Q8BP23	Gene names	Cnbp, Cnbp1, Znf9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

ZN189_HUMAN
NC score	0.018478 (rank : 484)	θ value	3.0926 (rank : 243)
Query Neighborhood Hits	298	Target Neighborhood Hits	754	Shared Neighborhood Hits	51
SwissProt Accessions	O75820, O75802, Q5T7D9, Q9UBL4, Q9UPE9, Q9UPF0, Q9UPF1	Gene names	ZNF189
Domain Architecture
Description	Zinc finger protein 189.

TRI32_HUMAN
NC score	0.018249 (rank : 485)	θ value	0.62314 (rank : 174)
Query Neighborhood Hits	298	Target Neighborhood Hits	264	Shared Neighborhood Hits	12
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

ZN700_HUMAN
NC score	0.018176 (rank : 486)	θ value	0.62314 (rank : 176)
Query Neighborhood Hits	298	Target Neighborhood Hits	772	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H0M5	Gene names	ZNF700
Domain Architecture	No domain graphic available
Description	Zinc finger protein 700.

ZN226_HUMAN
NC score	0.017983 (rank : 487)	θ value	3.0926 (rank : 244)
Query Neighborhood Hits	298	Target Neighborhood Hits	770	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NYT6, Q96TE6, Q9NS44	Gene names	ZNF226
Domain Architecture
Description	Zinc finger protein 226.

ZN615_HUMAN
NC score	0.017773 (rank : 488)	θ value	3.0926 (rank : 248)
Query Neighborhood Hits	298	Target Neighborhood Hits	775	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N8J6	Gene names	ZNF615
Domain Architecture	No domain graphic available
Description	Zinc finger protein 615.

ZN228_HUMAN
NC score	0.017766 (rank : 489)	θ value	3.0926 (rank : 245)
Query Neighborhood Hits	298	Target Neighborhood Hits	775	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UJU3, Q9HCA7	Gene names	ZNF228
Domain Architecture
Description	Zinc finger protein 228.

TRI32_MOUSE
NC score	0.017181 (rank : 490)	θ value	1.06291 (rank : 192)
Query Neighborhood Hits	298	Target Neighborhood Hits	271	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

ZN133_HUMAN
NC score	0.017114 (rank : 491)	θ value	0.279714 (rank : 154)
Query Neighborhood Hits	298	Target Neighborhood Hits	784	Shared Neighborhood Hits	52
SwissProt Accessions	P52736, Q9BUV2, Q9H443	Gene names	ZNF133
Domain Architecture
Description	Zinc finger protein 133.

ZFP28_HUMAN
NC score	0.017025 (rank : 492)	θ value	1.81305 (rank : 214)
Query Neighborhood Hits	298	Target Neighborhood Hits	843	Shared Neighborhood Hits	54
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

ZN569_HUMAN
NC score	0.016939 (rank : 493)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	298	Target Neighborhood Hits	759	Shared Neighborhood Hits	55
SwissProt Accessions	Q5MCW4, Q15925, Q96MQ2	Gene names	ZNF569
Domain Architecture	No domain graphic available
Description	Zinc finger protein 569.

ZN285_HUMAN
NC score	0.016718 (rank : 494)	θ value	3.0926 (rank : 247)
Query Neighborhood Hits	298	Target Neighborhood Hits	728	Shared Neighborhood Hits	54
SwissProt Accessions	Q96NJ3	Gene names	ZNF285
Domain Architecture	No domain graphic available
Description	Zinc finger protein 285.

ZN343_HUMAN
NC score	0.016653 (rank : 495)	θ value	0.62314 (rank : 175)
Query Neighborhood Hits	298	Target Neighborhood Hits	768	Shared Neighborhood Hits	52
SwissProt Accessions	Q6P1L6, Q5JXU8, Q5JXU9, Q8N8F2, Q96EX8, Q96NA5, Q9BQB0	Gene names	ZNF343
Domain Architecture	No domain graphic available
Description	Zinc finger protein 343.

ZN563_HUMAN
NC score	0.016477 (rank : 496)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	298	Target Neighborhood Hits	754	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TA94, Q8NAT7	Gene names	ZNF563
Domain Architecture	No domain graphic available
Description	Zinc finger protein 563.

ZN491_HUMAN
NC score	0.016428 (rank : 497)	θ value	1.81305 (rank : 216)
Query Neighborhood Hits	298	Target Neighborhood Hits	734	Shared Neighborhood Hits	51
SwissProt Accessions	Q8N8L2, Q8NAT8	Gene names	ZNF491
Domain Architecture	No domain graphic available
Description	Zinc finger protein 491.

ZN197_HUMAN
NC score	0.016353 (rank : 498)	θ value	0.813845 (rank : 183)
Query Neighborhood Hits	298	Target Neighborhood Hits	788	Shared Neighborhood Hits	51
SwissProt Accessions	O14709	Gene names	ZNF197, ZNF166
Domain Architecture
Description	Zinc finger protein 197 (ZnF20).

ZN236_HUMAN
NC score	0.016289 (rank : 499)	θ value	0.47712 (rank : 168)
Query Neighborhood Hits	298	Target Neighborhood Hits	844	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

ZN442_HUMAN
NC score	0.016207 (rank : 500)	θ value	6.88961 (rank : 284)
Query Neighborhood Hits	298	Target Neighborhood Hits	744	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H7R0	Gene names	ZNF442
Domain Architecture
Description	Zinc finger protein 442.

DGKG_MOUSE
NC score	0.016157 (rank : 501)	θ value	0.279714 (rank : 151)
Query Neighborhood Hits	298	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

MIZF_MOUSE
NC score	0.016118 (rank : 502)	θ value	4.03905 (rank : 253)
Query Neighborhood Hits	298	Target Neighborhood Hits	726	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K1K9, Q8BWY0	Gene names	Mizf
Domain Architecture	No domain graphic available
Description	MBD2-interacting zinc finger protein (Methyl-CpG-binding protein 2- interacting zinc finger protein).

DGKG_HUMAN
NC score	0.015976 (rank : 503)	θ value	0.21417 (rank : 146)
Query Neighborhood Hits	298	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

HKR1_HUMAN
NC score	0.015971 (rank : 504)	θ value	1.06291 (rank : 187)
Query Neighborhood Hits	298	Target Neighborhood Hits	759	Shared Neighborhood Hits	47
SwissProt Accessions	P10072, Q9BSW9, Q9UM09	Gene names	HKR1
Domain Architecture
Description	Krueppel-related zinc finger protein 1 (Protein HKR1).

ASM3A_HUMAN
NC score	0.015839 (rank : 505)	θ value	1.38821 (rank : 198)
Query Neighborhood Hits	298	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q92484, Q8WV13	Gene names	SMPDL3A, ASML3A
Domain Architecture	No domain graphic available
Description	Acid sphingomyelinase-like phosphodiesterase 3a precursor (EC 3.1.4.-) (ASM-like phosphodiesterase 3a).

PRDM5_HUMAN
NC score	0.015753 (rank : 506)	θ value	5.27518 (rank : 265)
Query Neighborhood Hits	298	Target Neighborhood Hits	790	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NQX1	Gene names	PRDM5, PFM2
Domain Architecture
Description	PR domain zinc finger protein 5 (PR domain-containing protein 5).

ZN239_HUMAN
NC score	0.015597 (rank : 507)	θ value	3.0926 (rank : 246)
Query Neighborhood Hits	298	Target Neighborhood Hits	746	Shared Neighborhood Hits	53
SwissProt Accessions	Q16600, Q5T1G9, Q8TAS5	Gene names	ZNF239, HOK2, MOK2
Domain Architecture	No domain graphic available
Description	Zinc finger protein 239 (Zinc finger protein MOK-2) (HOK-2).

ZN575_MOUSE
NC score	0.015453 (rank : 508)	θ value	1.06291 (rank : 194)
Query Neighborhood Hits	298	Target Neighborhood Hits	715	Shared Neighborhood Hits	46
SwissProt Accessions	Q3TXZ1	Gene names	Znf575, Zfp575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

TRIM8_HUMAN
NC score	0.015314 (rank : 509)	θ value	0.163984 (rank : 144)
Query Neighborhood Hits	298	Target Neighborhood Hits	650	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

OVOL2_HUMAN
NC score	0.015214 (rank : 510)	θ value	1.81305 (rank : 212)
Query Neighborhood Hits	298	Target Neighborhood Hits	715	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BRP0, Q5T8B4, Q9BX22, Q9HA54, Q9Y4M0	Gene names	OVOL2, ZNF339
Domain Architecture	No domain graphic available
Description	Transcription factor Ovo-like 2 (hOvo2) (Zinc finger protein 339).

ZN570_HUMAN
NC score	0.015051 (rank : 511)	θ value	1.81305 (rank : 217)
Query Neighborhood Hits	298	Target Neighborhood Hits	758	Shared Neighborhood Hits	49
SwissProt Accessions	Q96NI8	Gene names	ZNF570
Domain Architecture	No domain graphic available
Description	Zinc finger protein 570.

ZN239_MOUSE
NC score	0.014779 (rank : 512)	θ value	4.03905 (rank : 258)
Query Neighborhood Hits	298	Target Neighborhood Hits	723	Shared Neighborhood Hits	47
SwissProt Accessions	P24399	Gene names	Znf239, Mok-2, Mok2, Zfp239
Domain Architecture	No domain graphic available
Description	Zinc finger protein 239 (Zfp-239) (Zinc finger protein MOK-2).

TRIM8_MOUSE
NC score	0.014681 (rank : 513)	θ value	0.47712 (rank : 166)
Query Neighborhood Hits	298	Target Neighborhood Hits	674	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ZN575_HUMAN
NC score	0.014459 (rank : 514)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	298	Target Neighborhood Hits	739	Shared Neighborhood Hits	46
SwissProt Accessions	Q86XF7	Gene names	ZNF575
Domain Architecture	No domain graphic available
Description	Zinc finger protein 575.

ZN694_HUMAN
NC score	0.014238 (rank : 515)	θ value	5.27518 (rank : 271)
Query Neighborhood Hits	298	Target Neighborhood Hits	764	Shared Neighborhood Hits	49
SwissProt Accessions	Q63HK3, Q6ZN77	Gene names	ZNF694
Domain Architecture	No domain graphic available
Description	Zinc finger protein 694.

ZNF22_HUMAN
NC score	0.013983 (rank : 516)	θ value	1.06291 (rank : 197)
Query Neighborhood Hits	298	Target Neighborhood Hits	723	Shared Neighborhood Hits	45
SwissProt Accessions	P17026, Q96FM4	Gene names	ZNF22, KOX15, KROX26
Domain Architecture	No domain graphic available
Description	Zinc finger protein 22 (Zinc finger protein KOX15) (Krox-26 protein).

MYNN_HUMAN
NC score	0.013779 (rank : 517)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	298	Target Neighborhood Hits	826	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NPC7, Q6QHA6, Q6QHA7, Q6R3G1, Q6R3G2, Q6R4A0, Q7Z716, Q7Z717, Q86Z11, Q86Z12, Q9NS01, Q9UIW8	Gene names	MYNN, OSZF, ZBTB31
Domain Architecture	No domain graphic available
Description	Myoneurin (Zinc finger and BTB domain-containing protein 31).

ASM3A_MOUSE
NC score	0.013364 (rank : 518)	θ value	4.03905 (rank : 249)
Query Neighborhood Hits	298	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P70158	Gene names	Smpdl3a, Asml3a
Domain Architecture
Description	Acid sphingomyelinase-like phosphodiesterase 3a precursor (EC 3.1.4.-) (ASM-like phosphodiesterase 3a).

POLI_MOUSE
NC score	0.010606 (rank : 519)	θ value	2.36792 (rank : 225)
Query Neighborhood Hits	298	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q6R3M4, Q641P1, Q6R3M3, Q9R1A6	Gene names	Poli, Rad30b
Domain Architecture	No domain graphic available
Description	DNA polymerase iota (EC 2.7.7.7) (Rad30 homolog B).

TIF1G_HUMAN
NC score	0.009788 (rank : 520)	θ value	3.0926 (rank : 239)
Query Neighborhood Hits	298	Target Neighborhood Hits	410	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

HIOM_HUMAN
NC score	0.009754 (rank : 521)	θ value	6.88961 (rank : 280)
Query Neighborhood Hits	298	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	P46597, Q16598, Q5JQ72, Q5JQ73	Gene names	ASMT
Domain Architecture
Description	Hydroxyindole O-methyltransferase (EC 2.1.1.4) (HIOMT) (Acetylserotonin O-methyltransferase) (ASMT).

TIF1G_MOUSE
NC score	0.009192 (rank : 522)	θ value	4.03905 (rank : 256)
Query Neighborhood Hits	298	Target Neighborhood Hits	498	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

SPRE1_MOUSE
NC score	0.008787 (rank : 523)	θ value	5.27518 (rank : 266)
Query Neighborhood Hits	298	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	Q924S8, Q6PET8	Gene names	Spred1
Domain Architecture	No domain graphic available
Description	Sprouty-related, EVH1 domain-containing protein 1 (Spred-1).

TAF6L_MOUSE
NC score	0.008642 (rank : 524)	θ value	4.03905 (rank : 255)
Query Neighborhood Hits	298	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

MLL4_HUMAN
NC score	0.008581 (rank : 525)	θ value	4.03905 (rank : 254)
Query Neighborhood Hits	298	Target Neighborhood Hits	722	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

2ACA_HUMAN
NC score	0.005951 (rank : 526)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	298	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q06190, Q06189, Q9NPQ5	Gene names	PPP2R3A, PPP2R3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B (PP2A, subunit B, B''-PR72/PR130) (PP2A, subunit B, B72/B130 isoforms) (PP2A, subunit B, PR72/PR130 isoforms) (PP2A, subunit B, R3 isoform).

PAQR6_HUMAN
NC score	0.003145 (rank : 527)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	298	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q6TCH4, Q6PDU0, Q7Z4Q7, Q7Z4Q9, Q8N121, Q8N3M2, Q9H621	Gene names	PAQR6
Domain Architecture	No domain graphic available
Description	Progestin and adipoQ receptor family member 6 (Progestin and adipoQ receptor family member VI).

CO2_HUMAN
NC score	0.002337 (rank : 528)	θ value	6.88961 (rank : 274)
Query Neighborhood Hits	298	Target Neighborhood Hits	258	Shared Neighborhood Hits	8
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

LHX2_MOUSE
NC score	0.002087 (rank : 529)	θ value	4.03905 (rank : 252)
Query Neighborhood Hits	298	Target Neighborhood Hits	431	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0S2	Gene names	Lhx2
Domain Architecture
Description	LIM/homeobox protein Lhx2.

LHX2_HUMAN
NC score	0.002066 (rank : 530)	θ value	4.03905 (rank : 251)
Query Neighborhood Hits	298	Target Neighborhood Hits	432	Shared Neighborhood Hits	6
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

TRI27_MOUSE
NC score	0.001818 (rank : 531)	θ value	6.88961 (rank : 282)
Query Neighborhood Hits	298	Target Neighborhood Hits	261	Shared Neighborhood Hits	9
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

WDHD1_HUMAN
NC score	0.000608 (rank : 532)	θ value	6.88961 (rank : 283)
Query Neighborhood Hits	298	Target Neighborhood Hits	342	Shared Neighborhood Hits	3
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

FGD1_MOUSE
NC score	0.000351 (rank : 533)	θ value	6.88961 (rank : 279)
Query Neighborhood Hits	298	Target Neighborhood Hits	387	Shared Neighborhood Hits	7
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

FOXL1_MOUSE
NC score	-0.000641 (rank : 534)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	298	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

LAP4_MOUSE
NC score	-0.003557 (rank : 535)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	298	Target Neighborhood Hits	590	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).