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Network neighborhood for query Sequence : LCE1E_HUMAN

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LCE1E_HUMAN
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NOTC4_MOUSE
θ value	0.00869519 (rank : 1)	NC score	0.283081 (rank : 71)
Query Neighborhood Hits	53	Target Neighborhood Hits	872	Shared Neighborhood Hits	35
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

MEGF6_HUMAN
θ value	0.0148317 (rank : 2)	NC score	0.324370 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	671	Shared Neighborhood Hits	45
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

HTRA1_HUMAN
θ value	0.0193708 (rank : 3)	NC score	0.309405 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	155	Shared Neighborhood Hits	14
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

STAB1_MOUSE
θ value	0.0193708 (rank : 4)	NC score	0.288634 (rank : 65)
Query Neighborhood Hits	53	Target Neighborhood Hits	566	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

NOTC2_HUMAN
θ value	0.0252991 (rank : 5)	NC score	0.267707 (rank : 93)
Query Neighborhood Hits	53	Target Neighborhood Hits	1113	Shared Neighborhood Hits	35
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

GRN_MOUSE
θ value	0.0431538 (rank : 6)	NC score	0.422989 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	248	Shared Neighborhood Hits	30
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

SREC_HUMAN
θ value	0.0431538 (rank : 7)	NC score	0.357011 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	645	Shared Neighborhood Hits	36
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

GRN_HUMAN
θ value	0.0563607 (rank : 8)	NC score	0.416691 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	268	Shared Neighborhood Hits	33
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

HTRA4_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.308268 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	119	Shared Neighborhood Hits	7
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

TIE1_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.124836 (rank : 307)
Query Neighborhood Hits	53	Target Neighborhood Hits	1241	Shared Neighborhood Hits	31
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

ZAN_MOUSE
θ value	0.0961366 (rank : 11)	NC score	0.356519 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	808	Shared Neighborhood Hits	38
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

DLL3_HUMAN
θ value	0.125558 (rank : 12)	NC score	0.269671 (rank : 91)
Query Neighborhood Hits	53	Target Neighborhood Hits	419	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

NOTC4_HUMAN
θ value	0.21417 (rank : 13)	NC score	0.286884 (rank : 67)
Query Neighborhood Hits	53	Target Neighborhood Hits	905	Shared Neighborhood Hits	35
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

SREC2_MOUSE
θ value	0.21417 (rank : 14)	NC score	0.345393 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	605	Shared Neighborhood Hits	38
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SPR1A_MOUSE
θ value	0.279714 (rank : 15)	NC score	0.149715 (rank : 245)
Query Neighborhood Hits	53	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

HTRA3_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.305358 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

JAG2_HUMAN
θ value	0.365318 (rank : 17)	NC score	0.280768 (rank : 75)
Query Neighborhood Hits	53	Target Neighborhood Hits	491	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

SPR1A_HUMAN
θ value	0.365318 (rank : 18)	NC score	0.173648 (rank : 198)
Query Neighborhood Hits	53	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

KRHB6_MOUSE
θ value	0.47712 (rank : 19)	NC score	0.021129 (rank : 535)
Query Neighborhood Hits	53	Target Neighborhood Hits	413	Shared Neighborhood Hits	2
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

SSPO_MOUSE
θ value	0.47712 (rank : 20)	NC score	0.262077 (rank : 101)
Query Neighborhood Hits	53	Target Neighborhood Hits	800	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

WFDC3_HUMAN
θ value	0.62314 (rank : 21)	NC score	0.182071 (rank : 181)
Query Neighborhood Hits	53	Target Neighborhood Hits	138	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

HTRA3_MOUSE
θ value	0.813845 (rank : 22)	NC score	0.316147 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

SPR1B_MOUSE
θ value	0.813845 (rank : 23)	NC score	0.139069 (rank : 277)
Query Neighborhood Hits	53	Target Neighborhood Hits	395	Shared Neighborhood Hits	9
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

ZNFX1_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.201399 (rank : 163)
Query Neighborhood Hits	53	Target Neighborhood Hits	308	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

TENX_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.248573 (rank : 119)
Query Neighborhood Hits	53	Target Neighborhood Hits	789	Shared Neighborhood Hits	35
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

EGFR_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.044233 (rank : 534)
Query Neighborhood Hits	53	Target Neighborhood Hits	939	Shared Neighborhood Hits	22
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

HTRA1_MOUSE
θ value	1.38821 (rank : 27)	NC score	0.303293 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	140	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

KR103_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.254844 (rank : 110)
Query Neighborhood Hits	53	Target Neighborhood Hits	212	Shared Neighborhood Hits	32
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

TECTA_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.211345 (rank : 148)
Query Neighborhood Hits	53	Target Neighborhood Hits	239	Shared Neighborhood Hits	27
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TIE1_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.123038 (rank : 312)
Query Neighborhood Hits	53	Target Neighborhood Hits	1266	Shared Neighborhood Hits	32
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

SPR1B_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.181863 (rank : 183)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

CRIM1_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.282191 (rank : 73)
Query Neighborhood Hits	53	Target Neighborhood Hits	362	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

EZH1_MOUSE
θ value	2.36792 (rank : 33)	NC score	0.060731 (rank : 451)
Query Neighborhood Hits	53	Target Neighborhood Hits	126	Shared Neighborhood Hits	18
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

FRAS1_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.232207 (rank : 129)
Query Neighborhood Hits	53	Target Neighborhood Hits	747	Shared Neighborhood Hits	37
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KRA24_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.140345 (rank : 272)
Query Neighborhood Hits	53	Target Neighborhood Hits	192	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

NOTC3_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.275314 (rank : 79)
Query Neighborhood Hits	53	Target Neighborhood Hits	975	Shared Neighborhood Hits	34
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

RSPO4_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.103315 (rank : 351)
Query Neighborhood Hits	53	Target Neighborhood Hits	110	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

STAB1_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.286923 (rank : 66)
Query Neighborhood Hits	53	Target Neighborhood Hits	546	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

NOTC2_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.273356 (rank : 87)
Query Neighborhood Hits	53	Target Neighborhood Hits	1069	Shared Neighborhood Hits	34
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CP003_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.070490 (rank : 415)
Query Neighborhood Hits	53	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

MUC5B_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.257342 (rank : 108)
Query Neighborhood Hits	53	Target Neighborhood Hits	1020	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

IBP1_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.063174 (rank : 439)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

SREC2_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.348342 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	645	Shared Neighborhood Hits	38
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

STAB2_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.278035 (rank : 78)
Query Neighborhood Hits	53	Target Neighborhood Hits	534	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

VWF_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.264359 (rank : 98)
Query Neighborhood Hits	53	Target Neighborhood Hits	396	Shared Neighborhood Hits	36
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ZNFX1_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.200224 (rank : 164)
Query Neighborhood Hits	53	Target Neighborhood Hits	407	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

VWF_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.265250 (rank : 95)
Query Neighborhood Hits	53	Target Neighborhood Hits	381	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ZN692_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.000242 (rank : 537)
Query Neighborhood Hits	53	Target Neighborhood Hits	751	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U381	Gene names	Znf692, Zfp692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.

AMHR2_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.019855 (rank : 536)
Query Neighborhood Hits	53	Target Neighborhood Hits	715	Shared Neighborhood Hits	9
SwissProt Accessions	Q16671, Q13762	Gene names	AMHR2, AMHR
Domain Architecture
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII).

ERBB3_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.056200 (rank : 475)
Query Neighborhood Hits	53	Target Neighborhood Hits	918	Shared Neighborhood Hits	25
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

MEGF8_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.203779 (rank : 158)
Query Neighborhood Hits	53	Target Neighborhood Hits	528	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TRBM_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.195306 (rank : 172)
Query Neighborhood Hits	53	Target Neighborhood Hits	361	Shared Neighborhood Hits	31
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ZAN_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.275168 (rank : 81)
Query Neighborhood Hits	53	Target Neighborhood Hits	679	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ADA11_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.057079 (rank : 469)
Query Neighborhood Hits	53	Target Neighborhood Hits	259	Shared Neighborhood Hits	22
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.058507 (rank : 461)
Query Neighborhood Hits	53	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA15_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.056168 (rank : 476)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	25
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.071641 (rank : 409)
Query Neighborhood Hits	53	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA33_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.058974 (rank : 458)
Query Neighborhood Hits	53	Target Neighborhood Hits	264	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.053223 (rank : 505)
Query Neighborhood Hits	53	Target Neighborhood Hits	231	Shared Neighborhood Hits	18
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM8_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.066331 (rank : 424)
Query Neighborhood Hits	53	Target Neighborhood Hits	327	Shared Neighborhood Hits	26
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.065771 (rank : 428)
Query Neighborhood Hits	53	Target Neighborhood Hits	326	Shared Neighborhood Hits	25
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.050507 (rank : 528)
Query Neighborhood Hits	53	Target Neighborhood Hits	243	Shared Neighborhood Hits	23
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.055722 (rank : 482)
Query Neighborhood Hits	53	Target Neighborhood Hits	325	Shared Neighborhood Hits	23
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

AGRIN_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.250885 (rank : 114)
Query Neighborhood Hits	53	Target Neighborhood Hits	582	Shared Neighborhood Hits	41
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ALK1_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.056521 (rank : 471)
Query Neighborhood Hits	53	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).

ANKR6_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.052742 (rank : 509)
Query Neighborhood Hits	53	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR15_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.060730 (rank : 452)
Query Neighborhood Hits	53	Target Neighborhood Hits	478	Shared Neighborhood Hits	5
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR23_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.054285 (rank : 494)
Query Neighborhood Hits	53	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANR38_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.054435 (rank : 492)
Query Neighborhood Hits	53	Target Neighborhood Hits	443	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR38_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.058192 (rank : 463)
Query Neighborhood Hits	53	Target Neighborhood Hits	512	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR41_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.055280 (rank : 486)
Query Neighborhood Hits	53	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANR47_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.054199 (rank : 496)
Query Neighborhood Hits	53	Target Neighborhood Hits	369	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ANR49_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.054245 (rank : 495)
Query Neighborhood Hits	53	Target Neighborhood Hits	282	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANR49_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.051865 (rank : 517)
Query Neighborhood Hits	53	Target Neighborhood Hits	285	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

APR3_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.078462 (rank : 384)
Query Neighborhood Hits	53	Target Neighborhood Hits	50	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.092032 (rank : 363)
Query Neighborhood Hits	53	Target Neighborhood Hits	61	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ASB16_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.050448 (rank : 530)
Query Neighborhood Hits	53	Target Neighborhood Hits	286	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB16_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.061948 (rank : 445)
Query Neighborhood Hits	53	Target Neighborhood Hits	306	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB8_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.053675 (rank : 501)
Query Neighborhood Hits	53	Target Neighborhood Hits	294	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.053008 (rank : 506)
Query Neighborhood Hits	53	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASTN_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.050160 (rank : 531)
Query Neighborhood Hits	53	Target Neighborhood Hits	98	Shared Neighborhood Hits	10
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ASZ1_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.051494 (rank : 524)
Query Neighborhood Hits	53	Target Neighborhood Hits	341	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASZ1_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.053780 (rank : 500)
Query Neighborhood Hits	53	Target Neighborhood Hits	319	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ATRN_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.142138 (rank : 265)
Query Neighborhood Hits	53	Target Neighborhood Hits	525	Shared Neighborhood Hits	25
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.134579 (rank : 285)
Query Neighborhood Hits	53	Target Neighborhood Hits	519	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BCL3_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.053625 (rank : 502)
Query Neighborhood Hits	53	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

BCL3_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.052569 (rank : 513)
Query Neighborhood Hits	53	Target Neighborhood Hits	388	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

BMPER_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.209567 (rank : 150)
Query Neighborhood Hits	53	Target Neighborhood Hits	175	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.216135 (rank : 145)
Query Neighborhood Hits	53	Target Neighborhood Hits	194	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BTC_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.054374 (rank : 493)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	12
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

C1QR1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.175861 (rank : 193)
Query Neighborhood Hits	53	Target Neighborhood Hits	493	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.174272 (rank : 197)
Query Neighborhood Hits	53	Target Neighborhood Hits	342	Shared Neighborhood Hits	26
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD248_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.147024 (rank : 250)
Query Neighborhood Hits	53	Target Neighborhood Hits	679	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.141769 (rank : 266)
Query Neighborhood Hits	53	Target Neighborhood Hits	578	Shared Neighborhood Hits	25
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD2A1_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.050625 (rank : 526)
Query Neighborhood Hits	53	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CD2A1_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.064033 (rank : 433)
Query Neighborhood Hits	53	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CD97_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.124498 (rank : 308)
Query Neighborhood Hits	53	Target Neighborhood Hits	353	Shared Neighborhood Hits	21
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.107652 (rank : 341)
Query Neighborhood Hits	53	Target Neighborhood Hits	295	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CDN2B_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.067242 (rank : 422)
Query Neighborhood Hits	53	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CDN2B_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.057230 (rank : 468)
Query Neighborhood Hits	53	Target Neighborhood Hits	201	Shared Neighborhood Hits	5
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CELR1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.087812 (rank : 372)
Query Neighborhood Hits	53	Target Neighborhood Hits	613	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.087737 (rank : 373)
Query Neighborhood Hits	53	Target Neighborhood Hits	617	Shared Neighborhood Hits	26
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.089448 (rank : 366)
Query Neighborhood Hits	53	Target Neighborhood Hits	657	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR2_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.082058 (rank : 381)
Query Neighborhood Hits	53	Target Neighborhood Hits	584	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR3_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.095074 (rank : 361)
Query Neighborhood Hits	53	Target Neighborhood Hits	680	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.095221 (rank : 360)
Query Neighborhood Hits	53	Target Neighborhood Hits	687	Shared Neighborhood Hits	28
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CFC1_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.142619 (rank : 261)
Query Neighborhood Hits	53	Target Neighborhood Hits	148	Shared Neighborhood Hits	17
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.123444 (rank : 311)
Query Neighborhood Hits	53	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CHRD_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.059888 (rank : 455)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.058220 (rank : 462)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CLC14_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.051074 (rank : 525)
Query Neighborhood Hits	53	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CO6_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.060752 (rank : 450)
Query Neighborhood Hits	53	Target Neighborhood Hits	331	Shared Neighborhood Hits	17
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.066288 (rank : 425)
Query Neighborhood Hits	53	Target Neighborhood Hits	278	Shared Neighborhood Hits	13
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8B_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.070160 (rank : 416)
Query Neighborhood Hits	53	Target Neighborhood Hits	224	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

COMP_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.133852 (rank : 286)
Query Neighborhood Hits	53	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.145665 (rank : 257)
Query Neighborhood Hits	53	Target Neighborhood Hits	290	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CRDL1_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.052630 (rank : 511)
Query Neighborhood Hits	53	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.058614 (rank : 459)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.077440 (rank : 388)
Query Neighborhood Hits	53	Target Neighborhood Hits	99	Shared Neighborhood Hits	11
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.071752 (rank : 407)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CREL1_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.195936 (rank : 171)
Query Neighborhood Hits	53	Target Neighborhood Hits	441	Shared Neighborhood Hits	28
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.188730 (rank : 179)
Query Neighborhood Hits	53	Target Neighborhood Hits	524	Shared Neighborhood Hits	30
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRUM1_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.230209 (rank : 131)
Query Neighborhood Hits	53	Target Neighborhood Hits	457	Shared Neighborhood Hits	27
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.233839 (rank : 125)
Query Neighborhood Hits	53	Target Neighborhood Hits	444	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.249047 (rank : 118)
Query Neighborhood Hits	53	Target Neighborhood Hits	453	Shared Neighborhood Hits	30
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CSPG2_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.139954 (rank : 273)
Query Neighborhood Hits	53	Target Neighborhood Hits	681	Shared Neighborhood Hits	23
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.142292 (rank : 264)
Query Neighborhood Hits	53	Target Neighborhood Hits	711	Shared Neighborhood Hits	23
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.133718 (rank : 287)
Query Neighborhood Hits	53	Target Neighborhood Hits	676	Shared Neighborhood Hits	22
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.133649 (rank : 288)
Query Neighborhood Hits	53	Target Neighborhood Hits	657	Shared Neighborhood Hits	22
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CT127_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.077644 (rank : 386)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CTGF_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.101799 (rank : 353)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	25
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

CTGF_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.084473 (rank : 379)
Query Neighborhood Hits	53	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

CUBN_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.196726 (rank : 168)
Query Neighborhood Hits	53	Target Neighborhood Hits	482	Shared Neighborhood Hits	30
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.191080 (rank : 177)
Query Neighborhood Hits	53	Target Neighborhood Hits	477	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CYR61_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.112343 (rank : 334)
Query Neighborhood Hits	53	Target Neighborhood Hits	159	Shared Neighborhood Hits	24
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.113535 (rank : 329)
Query Neighborhood Hits	53	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DLK_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.256035 (rank : 109)
Query Neighborhood Hits	53	Target Neighborhood Hits	401	Shared Neighborhood Hits	33
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.252858 (rank : 113)
Query Neighborhood Hits	53	Target Neighborhood Hits	374	Shared Neighborhood Hits	27
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.249370 (rank : 117)
Query Neighborhood Hits	53	Target Neighborhood Hits	455	Shared Neighborhood Hits	32
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.250168 (rank : 115)
Query Neighborhood Hits	53	Target Neighborhood Hits	456	Shared Neighborhood Hits	31
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.268795 (rank : 92)
Query Neighborhood Hits	53	Target Neighborhood Hits	399	Shared Neighborhood Hits	30
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.260142 (rank : 107)
Query Neighborhood Hits	53	Target Neighborhood Hits	435	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.261392 (rank : 104)
Query Neighborhood Hits	53	Target Neighborhood Hits	440	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.249415 (rank : 116)
Query Neighborhood Hits	53	Target Neighborhood Hits	460	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.242996 (rank : 122)
Query Neighborhood Hits	53	Target Neighborhood Hits	413	Shared Neighborhood Hits	27
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.172694 (rank : 202)
Query Neighborhood Hits	53	Target Neighborhood Hits	292	Shared Neighborhood Hits	23
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.178966 (rank : 187)
Query Neighborhood Hits	53	Target Neighborhood Hits	317	Shared Neighborhood Hits	24
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.202837 (rank : 160)
Query Neighborhood Hits	53	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.197899 (rank : 167)
Query Neighborhood Hits	53	Target Neighborhood Hits	287	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.176795 (rank : 191)
Query Neighborhood Hits	53	Target Neighborhood Hits	270	Shared Neighborhood Hits	21
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.168043 (rank : 210)
Query Neighborhood Hits	53	Target Neighborhood Hits	266	Shared Neighborhood Hits	19
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.253291 (rank : 112)
Query Neighborhood Hits	53	Target Neighborhood Hits	365	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.253453 (rank : 111)
Query Neighborhood Hits	53	Target Neighborhood Hits	379	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.142617 (rank : 262)
Query Neighborhood Hits	53	Target Neighborhood Hits	343	Shared Neighborhood Hits	29
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.163027 (rank : 219)
Query Neighborhood Hits	53	Target Neighborhood Hits	358	Shared Neighborhood Hits	30
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

EHMT2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.056154 (rank : 477)
Query Neighborhood Hits	53	Target Neighborhood Hits	498	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.055732 (rank : 481)
Query Neighborhood Hits	53	Target Neighborhood Hits	750	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ELTD1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.076627 (rank : 391)
Query Neighborhood Hits	53	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.105244 (rank : 347)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.146566 (rank : 251)
Query Neighborhood Hits	53	Target Neighborhood Hits	382	Shared Neighborhood Hits	25
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.138981 (rank : 278)
Query Neighborhood Hits	53	Target Neighborhood Hits	349	Shared Neighborhood Hits	24
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.124274 (rank : 309)
Query Neighborhood Hits	53	Target Neighborhood Hits	345	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EPGN_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.054532 (rank : 490)
Query Neighborhood Hits	53	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

ERBB3_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.051749 (rank : 520)
Query Neighborhood Hits	53	Target Neighborhood Hits	898	Shared Neighborhood Hits	23
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.050615 (rank : 527)
Query Neighborhood Hits	53	Target Neighborhood Hits	910	Shared Neighborhood Hits	23
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

EREG_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.055527 (rank : 483)
Query Neighborhood Hits	53	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ESM1_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.290138 (rank : 64)
Query Neighborhood Hits	53	Target Neighborhood Hits	110	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.261531 (rank : 103)
Query Neighborhood Hits	53	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

EZH1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.060890 (rank : 449)
Query Neighborhood Hits	53	Target Neighborhood Hits	121	Shared Neighborhood Hits	18
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.054141 (rank : 497)
Query Neighborhood Hits	53	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.054470 (rank : 491)
Query Neighborhood Hits	53	Target Neighborhood Hits	86	Shared Neighborhood Hits	13
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

FA10_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.063849 (rank : 434)
Query Neighborhood Hits	53	Target Neighborhood Hits	431	Shared Neighborhood Hits	23
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.064242 (rank : 431)
Query Neighborhood Hits	53	Target Neighborhood Hits	435	Shared Neighborhood Hits	23
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA12_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.074722 (rank : 397)
Query Neighborhood Hits	53	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.062620 (rank : 443)
Query Neighborhood Hits	53	Target Neighborhood Hits	404	Shared Neighborhood Hits	20
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.065974 (rank : 427)
Query Neighborhood Hits	53	Target Neighborhood Hits	421	Shared Neighborhood Hits	23
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FAT2_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.076764 (rank : 390)
Query Neighborhood Hits	53	Target Neighborhood Hits	507	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FATH_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.101521 (rank : 355)
Query Neighborhood Hits	53	Target Neighborhood Hits	570	Shared Neighborhood Hits	24
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FBLN1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.193128 (rank : 174)
Query Neighborhood Hits	53	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.193059 (rank : 175)
Query Neighborhood Hits	53	Target Neighborhood Hits	329	Shared Neighborhood Hits	31
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.199756 (rank : 165)
Query Neighborhood Hits	53	Target Neighborhood Hits	392	Shared Neighborhood Hits	28
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.190797 (rank : 178)
Query Neighborhood Hits	53	Target Neighborhood Hits	505	Shared Neighborhood Hits	30
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.156826 (rank : 229)
Query Neighborhood Hits	53	Target Neighborhood Hits	293	Shared Neighborhood Hits	25
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.153713 (rank : 236)
Query Neighborhood Hits	53	Target Neighborhood Hits	279	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.170515 (rank : 206)
Query Neighborhood Hits	53	Target Neighborhood Hits	278	Shared Neighborhood Hits	28
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.165218 (rank : 216)
Query Neighborhood Hits	53	Target Neighborhood Hits	270	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.167294 (rank : 211)
Query Neighborhood Hits	53	Target Neighborhood Hits	329	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.166316 (rank : 214)
Query Neighborhood Hits	53	Target Neighborhood Hits	317	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.228509 (rank : 133)
Query Neighborhood Hits	53	Target Neighborhood Hits	557	Shared Neighborhood Hits	33
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.226795 (rank : 138)
Query Neighborhood Hits	53	Target Neighborhood Hits	563	Shared Neighborhood Hits	34
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.228879 (rank : 132)
Query Neighborhood Hits	53	Target Neighborhood Hits	560	Shared Neighborhood Hits	33
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.227774 (rank : 135)
Query Neighborhood Hits	53	Target Neighborhood Hits	549	Shared Neighborhood Hits	34
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.236312 (rank : 124)
Query Neighborhood Hits	53	Target Neighborhood Hits	543	Shared Neighborhood Hits	36
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FRAS1_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.226918 (rank : 136)
Query Neighborhood Hits	53	Target Neighborhood Hits	759	Shared Neighborhood Hits	38
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FSTL3_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.104170 (rank : 349)
Query Neighborhood Hits	53	Target Neighborhood Hits	162	Shared Neighborhood Hits	21
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.109401 (rank : 339)
Query Neighborhood Hits	53	Target Neighborhood Hits	152	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.085160 (rank : 377)
Query Neighborhood Hits	53	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.080382 (rank : 383)
Query Neighborhood Hits	53	Target Neighborhood Hits	146	Shared Neighborhood Hits	22
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GAS6_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.165427 (rank : 215)
Query Neighborhood Hits	53	Target Neighborhood Hits	348	Shared Neighborhood Hits	24
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.158314 (rank : 225)
Query Neighborhood Hits	53	Target Neighborhood Hits	343	Shared Neighborhood Hits	25
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GNPTA_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.074909 (rank : 396)
Query Neighborhood Hits	53	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GNPTA_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.073918 (rank : 402)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

HABP2_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.097522 (rank : 359)
Query Neighborhood Hits	53	Target Neighborhood Hits	431	Shared Neighborhood Hits	21
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.099322 (rank : 357)
Query Neighborhood Hits	53	Target Neighborhood Hits	445	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HGFA_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.075850 (rank : 392)
Query Neighborhood Hits	53	Target Neighborhood Hits	436	Shared Neighborhood Hits	22
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.081480 (rank : 382)
Query Neighborhood Hits	53	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HHIP_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.181302 (rank : 184)
Query Neighborhood Hits	53	Target Neighborhood Hits	249	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.170859 (rank : 203)
Query Neighborhood Hits	53	Target Neighborhood Hits	219	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HMCN1_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.121092 (rank : 319)
Query Neighborhood Hits	53	Target Neighborhood Hits	983	Shared Neighborhood Hits	32
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HTRA2_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.274056 (rank : 84)
Query Neighborhood Hits	53	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.274901 (rank : 82)
Query Neighborhood Hits	53	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

IBP1_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.087865 (rank : 371)
Query Neighborhood Hits	53	Target Neighborhood Hits	97	Shared Neighborhood Hits	14
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP2_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.056955 (rank : 470)
Query Neighborhood Hits	53	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP2_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.051689 (rank : 522)
Query Neighborhood Hits	53	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP3_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.068700 (rank : 420)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP3_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.055793 (rank : 480)
Query Neighborhood Hits	53	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP4_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.051800 (rank : 518)
Query Neighborhood Hits	53	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.050135 (rank : 532)
Query Neighborhood Hits	53	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP5_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.056420 (rank : 473)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.056499 (rank : 472)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP7_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.146251 (rank : 254)
Query Neighborhood Hits	53	Target Neighborhood Hits	220	Shared Neighborhood Hits	11
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.141521 (rank : 267)
Query Neighborhood Hits	53	Target Neighborhood Hits	230	Shared Neighborhood Hits	13
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

IKBA_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.052978 (rank : 507)
Query Neighborhood Hits	53	Target Neighborhood Hits	280	Shared Neighborhood Hits	5
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

IKBA_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.052025 (rank : 516)
Query Neighborhood Hits	53	Target Neighborhood Hits	283	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

IKBE_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.055443 (rank : 485)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	5
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ITB1_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.121973 (rank : 316)
Query Neighborhood Hits	53	Target Neighborhood Hits	298	Shared Neighborhood Hits	25
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.124061 (rank : 310)
Query Neighborhood Hits	53	Target Neighborhood Hits	283	Shared Neighborhood Hits	24
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.150784 (rank : 242)
Query Neighborhood Hits	53	Target Neighborhood Hits	282	Shared Neighborhood Hits	28
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.150411 (rank : 243)
Query Neighborhood Hits	53	Target Neighborhood Hits	326	Shared Neighborhood Hits	30
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.146364 (rank : 252)
Query Neighborhood Hits	53	Target Neighborhood Hits	325	Shared Neighborhood Hits	26
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.145685 (rank : 256)
Query Neighborhood Hits	53	Target Neighborhood Hits	319	Shared Neighborhood Hits	28
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB4_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.158792 (rank : 223)
Query Neighborhood Hits	53	Target Neighborhood Hits	458	Shared Neighborhood Hits	29
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.141151 (rank : 270)
Query Neighborhood Hits	53	Target Neighborhood Hits	310	Shared Neighborhood Hits	26
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.150237 (rank : 244)
Query Neighborhood Hits	53	Target Neighborhood Hits	329	Shared Neighborhood Hits	30
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.157922 (rank : 226)
Query Neighborhood Hits	53	Target Neighborhood Hits	318	Shared Neighborhood Hits	28
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.155182 (rank : 231)
Query Neighborhood Hits	53	Target Neighborhood Hits	341	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.157341 (rank : 228)
Query Neighborhood Hits	53	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.151381 (rank : 240)
Query Neighborhood Hits	53	Target Neighborhood Hits	277	Shared Neighborhood Hits	26
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.129793 (rank : 298)
Query Neighborhood Hits	53	Target Neighborhood Hits	280	Shared Neighborhood Hits	26
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

JAG1_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.275290 (rank : 80)
Query Neighborhood Hits	53	Target Neighborhood Hits	514	Shared Neighborhood Hits	33
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.273833 (rank : 85)
Query Neighborhood Hits	53	Target Neighborhood Hits	518	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.281192 (rank : 74)
Query Neighborhood Hits	53	Target Neighborhood Hits	504	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KAZD1_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.116597 (rank : 323)
Query Neighborhood Hits	53	Target Neighborhood Hits	248	Shared Neighborhood Hits	11
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.102253 (rank : 352)
Query Neighborhood Hits	53	Target Neighborhood Hits	281	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KR101_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.369536 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	261	Shared Neighborhood Hits	37
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.341738 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.378168 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	313	Shared Neighborhood Hits	36
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.335717 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	271	Shared Neighborhood Hits	35
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.358545 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	347	Shared Neighborhood Hits	37
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.371371 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	330	Shared Neighborhood Hits	39
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.339799 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	226	Shared Neighborhood Hits	36
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.340752 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	226	Shared Neighborhood Hits	34
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.228442 (rank : 134)
Query Neighborhood Hits	53	Target Neighborhood Hits	232	Shared Neighborhood Hits	31
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.308841 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	269	Shared Neighborhood Hits	34
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.309875 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	219	Shared Neighborhood Hits	33
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR121_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.056393 (rank : 474)
Query Neighborhood Hits	53	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

KR122_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.112694 (rank : 331)
Query Neighborhood Hits	53	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR124_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.067987 (rank : 421)
Query Neighborhood Hits	53	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KR171_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.399869 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR211_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.083530 (rank : 380)
Query Neighborhood Hits	53	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q3LI58	Gene names	KRTAP21-1, KAP21.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 21-1.

KR410_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.226889 (rank : 137)
Query Neighborhood Hits	53	Target Neighborhood Hits	156	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.280432 (rank : 76)
Query Neighborhood Hits	53	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.157660 (rank : 227)
Query Neighborhood Hits	53	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.265614 (rank : 94)
Query Neighborhood Hits	53	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.345276 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	217	Shared Neighborhood Hits	36
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.402065 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.263338 (rank : 99)
Query Neighborhood Hits	53	Target Neighborhood Hits	155	Shared Neighborhood Hits	24
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.300208 (rank : 60)
Query Neighborhood Hits	53	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.283465 (rank : 69)
Query Neighborhood Hits	53	Target Neighborhood Hits	126	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA42_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.174886 (rank : 196)
Query Neighborhood Hits	53	Target Neighborhood Hits	149	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.282490 (rank : 72)
Query Neighborhood Hits	53	Target Neighborhood Hits	162	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.290577 (rank : 63)
Query Neighborhood Hits	53	Target Neighborhood Hits	194	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.295047 (rank : 62)
Query Neighborhood Hits	53	Target Neighborhood Hits	204	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.378540 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	34
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.331933 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	236	Shared Neighborhood Hits	33
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.394603 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.368327 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	270	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.357150 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	257	Shared Neighborhood Hits	34
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.380922 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	207	Shared Neighborhood Hits	34
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.362628 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.374371 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	324	Shared Neighborhood Hits	37
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.348895 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	310	Shared Neighborhood Hits	36
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA61_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.060098 (rank : 454)
Query Neighborhood Hits	53	Target Neighborhood Hits	5	Shared Neighborhood Hits	1
SwissProt Accessions	Q3LI64	Gene names	KRTAP6-1, KAP6.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-1.

KRA63_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.064224 (rank : 432)
Query Neighborhood Hits	53	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q3LI67	Gene names	KRTAP6-3, KAP6.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-3.

KRA92_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.299923 (rank : 61)
Query Neighborhood Hits	53	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.285137 (rank : 68)
Query Neighborhood Hits	53	Target Neighborhood Hits	203	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.270884 (rank : 88)
Query Neighborhood Hits	53	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.316205 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	185	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.283248 (rank : 70)
Query Neighborhood Hits	53	Target Neighborhood Hits	173	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA1_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.175034 (rank : 195)
Query Neighborhood Hits	53	Target Neighborhood Hits	804	Shared Neighborhood Hits	34
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.176395 (rank : 192)
Query Neighborhood Hits	53	Target Neighborhood Hits	838	Shared Neighborhood Hits	35
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.173187 (rank : 200)
Query Neighborhood Hits	53	Target Neighborhood Hits	1092	Shared Neighborhood Hits	33
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.164459 (rank : 218)
Query Neighborhood Hits	53	Target Neighborhood Hits	1198	Shared Neighborhood Hits	33
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.122735 (rank : 314)
Query Neighborhood Hits	53	Target Neighborhood Hits	760	Shared Neighborhood Hits	25
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA3_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.141394 (rank : 268)
Query Neighborhood Hits	53	Target Neighborhood Hits	859	Shared Neighborhood Hits	30
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.113829 (rank : 328)
Query Neighborhood Hits	53	Target Neighborhood Hits	708	Shared Neighborhood Hits	21
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.118726 (rank : 321)
Query Neighborhood Hits	53	Target Neighborhood Hits	584	Shared Neighborhood Hits	21
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.211939 (rank : 147)
Query Neighborhood Hits	53	Target Neighborhood Hits	976	Shared Neighborhood Hits	37
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.204192 (rank : 157)
Query Neighborhood Hits	53	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.170853 (rank : 204)
Query Neighborhood Hits	53	Target Neighborhood Hits	1018	Shared Neighborhood Hits	29
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.177376 (rank : 189)
Query Neighborhood Hits	53	Target Neighborhood Hits	919	Shared Neighborhood Hits	30
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.198005 (rank : 166)
Query Neighborhood Hits	53	Target Neighborhood Hits	692	Shared Neighborhood Hits	29
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.196349 (rank : 170)
Query Neighborhood Hits	53	Target Neighborhood Hits	722	Shared Neighborhood Hits	30
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.162510 (rank : 220)
Query Neighborhood Hits	53	Target Neighborhood Hits	461	Shared Neighborhood Hits	27
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.166426 (rank : 213)
Query Neighborhood Hits	53	Target Neighborhood Hits	444	Shared Neighborhood Hits	27
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.148402 (rank : 248)
Query Neighborhood Hits	53	Target Neighborhood Hits	922	Shared Neighborhood Hits	30
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.155147 (rank : 232)
Query Neighborhood Hits	53	Target Neighborhood Hits	856	Shared Neighborhood Hits	26
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.161257 (rank : 221)
Query Neighborhood Hits	53	Target Neighborhood Hits	715	Shared Neighborhood Hits	26
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.165196 (rank : 217)
Query Neighborhood Hits	53	Target Neighborhood Hits	614	Shared Neighborhood Hits	31
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.177873 (rank : 188)
Query Neighborhood Hits	53	Target Neighborhood Hits	588	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.172720 (rank : 201)
Query Neighborhood Hits	53	Target Neighborhood Hits	624	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1A_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.802438 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.867264 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	58	Shared Neighborhood Hits	43
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.917766 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	65	Shared Neighborhood Hits	51
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.788249 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.887703 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.507091 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.495944 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.529739 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.535633 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.457580 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.168785 (rank : 209)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE3C_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.216427 (rank : 144)
Query Neighborhood Hits	53	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LCE3D_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.062326 (rank : 444)
Query Neighborhood Hits	53	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE3	Gene names	LCE3D, LEP16, SPRL6A, SPRL6B
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3D (Late envelope protein 16) (Small proline-rich-like epidermal differentiation complex protein 6A) (Small proline-rich-like epidermal differentiation complex protein 6B).

LCE3E_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.054852 (rank : 489)
Query Neighborhood Hits	53	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T5B0	Gene names	LCE3E, LEP17
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3E (Late envelope protein 17).

LCE4A_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.380160 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.590797 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LDLR_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.138790 (rank : 279)
Query Neighborhood Hits	53	Target Neighborhood Hits	375	Shared Neighborhood Hits	29
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.130810 (rank : 294)
Query Neighborhood Hits	53	Target Neighborhood Hits	382	Shared Neighborhood Hits	29
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LORI_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.221951 (rank : 140)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRP1B_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.173577 (rank : 199)
Query Neighborhood Hits	53	Target Neighborhood Hits	602	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.169689 (rank : 208)
Query Neighborhood Hits	53	Target Neighborhood Hits	606	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.180012 (rank : 185)
Query Neighborhood Hits	53	Target Neighborhood Hits	617	Shared Neighborhood Hits	35
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.145716 (rank : 255)
Query Neighborhood Hits	53	Target Neighborhood Hits	573	Shared Neighborhood Hits	33
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP4_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.110987 (rank : 335)
Query Neighborhood Hits	53	Target Neighborhood Hits	355	Shared Neighborhood Hits	25
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.109712 (rank : 337)
Query Neighborhood Hits	53	Target Neighborhood Hits	351	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.137692 (rank : 281)
Query Neighborhood Hits	53	Target Neighborhood Hits	346	Shared Neighborhood Hits	28
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.138722 (rank : 280)
Query Neighborhood Hits	53	Target Neighborhood Hits	385	Shared Neighborhood Hits	28
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.205745 (rank : 154)
Query Neighborhood Hits	53	Target Neighborhood Hits	553	Shared Neighborhood Hits	31
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.202038 (rank : 162)
Query Neighborhood Hits	53	Target Neighborhood Hits	514	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.204983 (rank : 156)
Query Neighborhood Hits	53	Target Neighborhood Hits	502	Shared Neighborhood Hits	30
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.202796 (rank : 161)
Query Neighborhood Hits	53	Target Neighborhood Hits	479	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.216615 (rank : 143)
Query Neighborhood Hits	53	Target Neighborhood Hits	552	Shared Neighborhood Hits	34
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.210282 (rank : 149)
Query Neighborhood Hits	53	Target Neighborhood Hits	617	Shared Neighborhood Hits	31
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.214123 (rank : 146)
Query Neighborhood Hits	53	Target Neighborhood Hits	502	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.209086 (rank : 152)
Query Neighborhood Hits	53	Target Neighborhood Hits	475	Shared Neighborhood Hits	32
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.233141 (rank : 127)
Query Neighborhood Hits	53	Target Neighborhood Hits	607	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LYAM1_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.071599 (rank : 411)
Query Neighborhood Hits	53	Target Neighborhood Hits	315	Shared Neighborhood Hits	18
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.085528 (rank : 376)
Query Neighborhood Hits	53	Target Neighborhood Hits	332	Shared Neighborhood Hits	19
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.101556 (rank : 354)
Query Neighborhood Hits	53	Target Neighborhood Hits	394	Shared Neighborhood Hits	19
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.091845 (rank : 364)
Query Neighborhood Hits	53	Target Neighborhood Hits	420	Shared Neighborhood Hits	21
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.099049 (rank : 358)
Query Neighborhood Hits	53	Target Neighborhood Hits	378	Shared Neighborhood Hits	22
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.119820 (rank : 320)
Query Neighborhood Hits	53	Target Neighborhood Hits	390	Shared Neighborhood Hits	26
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MATN2_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.175717 (rank : 194)
Query Neighborhood Hits	53	Target Neighborhood Hits	365	Shared Neighborhood Hits	29
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.181969 (rank : 182)
Query Neighborhood Hits	53	Target Neighborhood Hits	356	Shared Neighborhood Hits	31
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.134720 (rank : 283)
Query Neighborhood Hits	53	Target Neighborhood Hits	268	Shared Neighborhood Hits	24
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 358)	NC score	0.130780 (rank : 295)
Query Neighborhood Hits	53	Target Neighborhood Hits	261	Shared Neighborhood Hits	25
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.139110 (rank : 275)
Query Neighborhood Hits	53	Target Neighborhood Hits	287	Shared Neighborhood Hits	29
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.114564 (rank : 325)
Query Neighborhood Hits	53	Target Neighborhood Hits	277	Shared Neighborhood Hits	23
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCSP_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.209220 (rank : 151)
Query Neighborhood Hits	53	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MCSP_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.456257 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEGF8_MOUSE
θ value	θ > 10 (rank : 363)	NC score	0.203193 (rank : 159)
Query Neighborhood Hits	53	Target Neighborhood Hits	520	Shared Neighborhood Hits	29
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.188519 (rank : 180)
Query Neighborhood Hits	53	Target Neighborhood Hits	557	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.179561 (rank : 186)
Query Neighborhood Hits	53	Target Neighborhood Hits	896	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEP1A_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.052681 (rank : 510)
Query Neighborhood Hits	53	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.053910 (rank : 499)
Query Neighborhood Hits	53	Target Neighborhood Hits	166	Shared Neighborhood Hits	9
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MFGM_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.075793 (rank : 393)
Query Neighborhood Hits	53	Target Neighborhood Hits	150	Shared Neighborhood Hits	20
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.153993 (rank : 234)
Query Neighborhood Hits	53	Target Neighborhood Hits	233	Shared Neighborhood Hits	20
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MKS3_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.053392 (rank : 504)
Query Neighborhood Hits	53	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MMRN1_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.059380 (rank : 457)
Query Neighborhood Hits	53	Target Neighborhood Hits	636	Shared Neighborhood Hits	13
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MT1A_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.050491 (rank : 529)
Query Neighborhood Hits	53	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.075629 (rank : 394)
Query Neighborhood Hits	53	Target Neighborhood Hits	87	Shared Neighborhood Hits	12
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.063157 (rank : 440)
Query Neighborhood Hits	53	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.063809 (rank : 435)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.141225 (rank : 269)
Query Neighborhood Hits	53	Target Neighborhood Hits	82	Shared Neighborhood Hits	12
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.088550 (rank : 368)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.108289 (rank : 340)
Query Neighborhood Hits	53	Target Neighborhood Hits	83	Shared Neighborhood Hits	13
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.130186 (rank : 297)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.071043 (rank : 413)
Query Neighborhood Hits	53	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC13_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.074935 (rank : 395)
Query Neighborhood Hits	53	Target Neighborhood Hits	447	Shared Neighborhood Hits	17
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC2_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.206913 (rank : 153)
Query Neighborhood Hits	53	Target Neighborhood Hits	906	Shared Neighborhood Hits	29
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NAGPA_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.261577 (rank : 102)
Query Neighborhood Hits	53	Target Neighborhood Hits	282	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.264437 (rank : 96)
Query Neighborhood Hits	53	Target Neighborhood Hits	308	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.245364 (rank : 121)
Query Neighborhood Hits	53	Target Neighborhood Hits	451	Shared Neighborhood Hits	33
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.231536 (rank : 130)
Query Neighborhood Hits	53	Target Neighborhood Hits	449	Shared Neighborhood Hits	32
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.233031 (rank : 128)
Query Neighborhood Hits	53	Target Neighborhood Hits	436	Shared Neighborhood Hits	32
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NET1_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.057891 (rank : 465)
Query Neighborhood Hits	53	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.055455 (rank : 484)
Query Neighborhood Hits	53	Target Neighborhood Hits	151	Shared Neighborhood Hits	20
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET2_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.088043 (rank : 369)
Query Neighborhood Hits	53	Target Neighborhood Hits	194	Shared Neighborhood Hits	21
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.088889 (rank : 367)
Query Neighborhood Hits	53	Target Neighborhood Hits	193	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET4_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.106488 (rank : 344)
Query Neighborhood Hits	53	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.105284 (rank : 346)
Query Neighborhood Hits	53	Target Neighborhood Hits	180	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NEU1_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.063024 (rank : 441)
Query Neighborhood Hits	53	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

NFX1_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.246147 (rank : 120)
Query Neighborhood Hits	53	Target Neighborhood Hits	405	Shared Neighborhood Hits	32
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NICE1_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.063801 (rank : 436)
Query Neighborhood Hits	53	Target Neighborhood Hits	12	Shared Neighborhood Hits	1
SwissProt Accessions	Q9UGL9	Gene names	NICE1, C1orf42
Domain Architecture	No domain graphic available
Description	Protein NICE-1.

NID1_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.146343 (rank : 253)
Query Neighborhood Hits	53	Target Neighborhood Hits	329	Shared Neighborhood Hits	24
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.152970 (rank : 237)
Query Neighborhood Hits	53	Target Neighborhood Hits	335	Shared Neighborhood Hits	23
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.170732 (rank : 205)
Query Neighborhood Hits	53	Target Neighborhood Hits	456	Shared Neighborhood Hits	30
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.169711 (rank : 207)
Query Neighborhood Hits	53	Target Neighborhood Hits	338	Shared Neighborhood Hits	28
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC1_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.270403 (rank : 90)
Query Neighborhood Hits	53	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.274392 (rank : 83)
Query Neighborhood Hits	53	Target Neighborhood Hits	916	Shared Neighborhood Hits	34
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.273651 (rank : 86)
Query Neighborhood Hits	53	Target Neighborhood Hits	1062	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOV_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.092657 (rank : 362)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	21
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NOV_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.091246 (rank : 365)
Query Neighborhood Hits	53	Target Neighborhood Hits	130	Shared Neighborhood Hits	23
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NRG1_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.061089 (rank : 448)
Query Neighborhood Hits	53	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.063254 (rank : 438)
Query Neighborhood Hits	53	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.063407 (rank : 437)
Query Neighborhood Hits	53	Target Neighborhood Hits	392	Shared Neighborhood Hits	12
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG4_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.073370 (rank : 403)
Query Neighborhood Hits	53	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.076863 (rank : 389)
Query Neighborhood Hits	53	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NTNG1_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.132070 (rank : 292)
Query Neighborhood Hits	53	Target Neighborhood Hits	247	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.129441 (rank : 299)
Query Neighborhood Hits	53	Target Neighborhood Hits	246	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.144161 (rank : 258)
Query Neighborhood Hits	53	Target Neighborhood Hits	276	Shared Neighborhood Hits	26
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.143032 (rank : 260)
Query Neighborhood Hits	53	Target Neighborhood Hits	276	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ODFP_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.070607 (rank : 414)
Query Neighborhood Hits	53	Target Neighborhood Hits	75	Shared Neighborhood Hits	10
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PA2G6_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.052137 (rank : 515)
Query Neighborhood Hits	53	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PAPPA_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.066803 (rank : 423)
Query Neighborhood Hits	53	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.061678 (rank : 446)
Query Neighborhood Hits	53	Target Neighborhood Hits	153	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PCSK5_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.113013 (rank : 330)
Query Neighborhood Hits	53	Target Neighborhood Hits	291	Shared Neighborhood Hits	32
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK5_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.219719 (rank : 141)
Query Neighborhood Hits	53	Target Neighborhood Hits	613	Shared Neighborhood Hits	38
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK6_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.112651 (rank : 333)
Query Neighborhood Hits	53	Target Neighborhood Hits	298	Shared Neighborhood Hits	32
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PERT_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.059499 (rank : 456)
Query Neighborhood Hits	53	Target Neighborhood Hits	221	Shared Neighborhood Hits	12
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.057931 (rank : 464)
Query Neighborhood Hits	53	Target Neighborhood Hits	221	Shared Neighborhood Hits	14
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGBM_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.110977 (rank : 336)
Query Neighborhood Hits	53	Target Neighborhood Hits	1113	Shared Neighborhood Hits	33
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.114421 (rank : 326)
Query Neighborhood Hits	53	Target Neighborhood Hits	1073	Shared Neighborhood Hits	32
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGCA_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.071629 (rank : 410)
Query Neighborhood Hits	53	Target Neighborhood Hits	821	Shared Neighborhood Hits	22
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCB_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.078163 (rank : 385)
Query Neighborhood Hits	53	Target Neighborhood Hits	478	Shared Neighborhood Hits	15
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.085595 (rank : 375)
Query Neighborhood Hits	53	Target Neighborhood Hits	459	Shared Neighborhood Hits	15
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PGH2_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.052951 (rank : 508)
Query Neighborhood Hits	53	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.055969 (rank : 479)
Query Neighborhood Hits	53	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PRG4_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.065293 (rank : 429)
Query Neighborhood Hits	53	Target Neighborhood Hits	624	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PROC_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.058523 (rank : 460)
Query Neighborhood Hits	53	Target Neighborhood Hits	406	Shared Neighborhood Hits	19
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.072466 (rank : 406)
Query Neighborhood Hits	53	Target Neighborhood Hits	426	Shared Neighborhood Hits	22
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROP_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.052268 (rank : 514)
Query Neighborhood Hits	53	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROS_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.158674 (rank : 224)
Query Neighborhood Hits	53	Target Neighborhood Hits	340	Shared Neighborhood Hits	27
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.156549 (rank : 230)
Query Neighborhood Hits	53	Target Neighborhood Hits	330	Shared Neighborhood Hits	28
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.122692 (rank : 315)
Query Neighborhood Hits	53	Target Neighborhood Hits	422	Shared Neighborhood Hits	23
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.121771 (rank : 318)
Query Neighborhood Hits	53	Target Neighborhood Hits	410	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PRP2_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.060286 (rank : 453)
Query Neighborhood Hits	53	Target Neighborhood Hits	347	Shared Neighborhood Hits	6
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR13_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.062732 (rank : 442)
Query Neighborhood Hits	53	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PRR13_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.074006 (rank : 401)
Query Neighborhood Hits	53	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

PSD10_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.053591 (rank : 503)
Query Neighborhood Hits	53	Target Neighborhood Hits	301	Shared Neighborhood Hits	5
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.052603 (rank : 512)
Query Neighborhood Hits	53	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

RECK_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.142369 (rank : 263)
Query Neighborhood Hits	53	Target Neighborhood Hits	189	Shared Neighborhood Hits	25
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.139075 (rank : 276)
Query Neighborhood Hits	53	Target Neighborhood Hits	158	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RELN_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.086783 (rank : 374)
Query Neighborhood Hits	53	Target Neighborhood Hits	233	Shared Neighborhood Hits	19
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.087923 (rank : 370)
Query Neighborhood Hits	53	Target Neighborhood Hits	235	Shared Neighborhood Hits	19
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RSPO2_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.069956 (rank : 417)
Query Neighborhood Hits	53	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.071684 (rank : 408)
Query Neighborhood Hits	53	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO3_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.073320 (rank : 405)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.073365 (rank : 404)
Query Neighborhood Hits	53	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.100848 (rank : 356)
Query Neighborhood Hits	53	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SCUB3_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.192594 (rank : 176)
Query Neighborhood Hits	53	Target Neighborhood Hits	428	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.193534 (rank : 173)
Query Neighborhood Hits	53	Target Neighborhood Hits	442	Shared Neighborhood Hits	30
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SHAN1_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.066110 (rank : 426)
Query Neighborhood Hits	53	Target Neighborhood Hits	1041	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SLIT1_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.160385 (rank : 222)
Query Neighborhood Hits	53	Target Neighborhood Hits	700	Shared Neighborhood Hits	29
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.150806 (rank : 241)
Query Neighborhood Hits	53	Target Neighborhood Hits	715	Shared Neighborhood Hits	28
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.154780 (rank : 233)
Query Neighborhood Hits	53	Target Neighborhood Hits	708	Shared Neighborhood Hits	31
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.152356 (rank : 239)
Query Neighborhood Hits	53	Target Neighborhood Hits	684	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.152382 (rank : 238)
Query Neighborhood Hits	53	Target Neighborhood Hits	682	Shared Neighborhood Hits	27
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.153765 (rank : 235)
Query Neighborhood Hits	53	Target Neighborhood Hits	700	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SMDF_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.074071 (rank : 400)
Query Neighborhood Hits	53	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SMR1_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.054104 (rank : 498)
Query Neighborhood Hits	53	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

SORL_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.103379 (rank : 350)
Query Neighborhood Hits	53	Target Neighborhood Hits	440	Shared Neighborhood Hits	26
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 465)	NC score	0.122934 (rank : 313)
Query Neighborhood Hits	53	Target Neighborhood Hits	439	Shared Neighborhood Hits	32
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPR2A_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.241987 (rank : 123)
Query Neighborhood Hits	53	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	P35326	Gene names	SPRR2A
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A (SPR-2A) (2-1).

SPR2A_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.121827 (rank : 317)
Query Neighborhood Hits	53	Target Neighborhood Hits	35	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CQK8, O70553	Gene names	Sprr2a
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A.

SPR2B_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.264381 (rank : 97)
Query Neighborhood Hits	53	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	P35325, Q5T528	Gene names	SPRR2B
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B (SPR-2B).

SPR2B_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.373560 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.321161 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

SPR2D_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.429285 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	61	Shared Neighborhood Hits	23
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.360920 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2E_MOUSE
θ value	θ > 10 (rank : 473)	NC score	0.377395 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	45	Shared Neighborhood Hits	18
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.390030 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2F_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.368233 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2G_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.260609 (rank : 105)
Query Neighborhood Hits	53	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYE4	Gene names	SPRR2G
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G (SPR-2G).

SPR2G_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.391051 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.387374 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.392107 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SPR2K_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.270770 (rank : 89)
Query Neighborhood Hits	53	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	O70562	Gene names	Sprr2k
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2K.

SPRR3_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.131111 (rank : 293)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SPRR3_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.133431 (rank : 289)
Query Neighborhood Hits	53	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

SPRR4_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.128341 (rank : 302)
Query Neighborhood Hits	53	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PI1, Q2M1Y7, Q5T522	Gene names	SPRR4
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 4.

SPRR4_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.116880 (rank : 322)
Query Neighborhood Hits	53	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGN8	Gene names	Sprr4
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 4.

STAB2_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.278737 (rank : 77)
Query Neighborhood Hits	53	Target Neighborhood Hits	528	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SUSD1_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.134658 (rank : 284)
Query Neighborhood Hits	53	Target Neighborhood Hits	285	Shared Neighborhood Hits	19
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.109584 (rank : 338)
Query Neighborhood Hits	53	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.128766 (rank : 301)
Query Neighborhood Hits	53	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.107587 (rank : 343)
Query Neighborhood Hits	53	Target Neighborhood Hits	131	Shared Neighborhood Hits	15
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TECTA_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.217045 (rank : 142)
Query Neighborhood Hits	53	Target Neighborhood Hits	244	Shared Neighborhood Hits	29
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.126392 (rank : 305)
Query Neighborhood Hits	53	Target Neighborhood Hits	211	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.126450 (rank : 304)
Query Neighborhood Hits	53	Target Neighborhood Hits	214	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENA_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.233832 (rank : 126)
Query Neighborhood Hits	53	Target Neighborhood Hits	631	Shared Neighborhood Hits	36
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.224077 (rank : 139)
Query Neighborhood Hits	53	Target Neighborhood Hits	596	Shared Neighborhood Hits	32
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.137460 (rank : 282)
Query Neighborhood Hits	53	Target Neighborhood Hits	453	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.143091 (rank : 259)
Query Neighborhood Hits	53	Target Neighborhood Hits	484	Shared Neighborhood Hits	28
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.149537 (rank : 246)
Query Neighborhood Hits	53	Target Neighborhood Hits	526	Shared Neighborhood Hits	27
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.148077 (rank : 249)
Query Neighborhood Hits	53	Target Neighborhood Hits	531	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TIE2_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.107616 (rank : 342)
Query Neighborhood Hits	53	Target Neighborhood Hits	1192	Shared Neighborhood Hits	33
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.106237 (rank : 345)
Query Neighborhood Hits	53	Target Neighborhood Hits	1204	Shared Neighborhood Hits	34
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TNR14_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.077593 (rank : 387)
Query Neighborhood Hits	53	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR25_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.074722 (rank : 398)
Query Neighborhood Hits	53	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR7_HUMAN
θ value	θ > 10 (rank : 503)	NC score	0.057317 (rank : 467)
Query Neighborhood Hits	53	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR9_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.061269 (rank : 447)
Query Neighborhood Hits	53	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TRBM_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.205490 (rank : 155)
Query Neighborhood Hits	53	Target Neighborhood Hits	339	Shared Neighborhood Hits	33
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TROAP_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.050086 (rank : 533)
Query Neighborhood Hits	53	Target Neighborhood Hits	258	Shared Neighborhood Hits	6
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

TSG6_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.056125 (rank : 478)
Query Neighborhood Hits	53	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.055278 (rank : 487)
Query Neighborhood Hits	53	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP1_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.128822 (rank : 300)
Query Neighborhood Hits	53	Target Neighborhood Hits	389	Shared Neighborhood Hits	28
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.128122 (rank : 303)
Query Neighborhood Hits	53	Target Neighborhood Hits	396	Shared Neighborhood Hits	28
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.112676 (rank : 332)
Query Neighborhood Hits	53	Target Neighborhood Hits	359	Shared Neighborhood Hits	24
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.113919 (rank : 327)
Query Neighborhood Hits	53	Target Neighborhood Hits	352	Shared Neighborhood Hits	24
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.125883 (rank : 306)
Query Neighborhood Hits	53	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.130731 (rank : 296)
Query Neighborhood Hits	53	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.132800 (rank : 290)
Query Neighborhood Hits	53	Target Neighborhood Hits	277	Shared Neighborhood Hits	21
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.140352 (rank : 271)
Query Neighborhood Hits	53	Target Neighborhood Hits	276	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROL1_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.069134 (rank : 419)
Query Neighborhood Hits	53	Target Neighborhood Hits	213	Shared Neighborhood Hits	14
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.064484 (rank : 430)
Query Neighborhood Hits	53	Target Neighborhood Hits	235	Shared Neighborhood Hits	13
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.196395 (rank : 169)
Query Neighborhood Hits	53	Target Neighborhood Hits	284	Shared Neighborhood Hits	28
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.177035 (rank : 190)
Query Neighborhood Hits	53	Target Neighborhood Hits	276	Shared Neighborhood Hits	27
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.148751 (rank : 247)
Query Neighborhood Hits	53	Target Neighborhood Hits	600	Shared Neighborhood Hits	26
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.166523 (rank : 212)
Query Neighborhood Hits	53	Target Neighborhood Hits	626	Shared Neighborhood Hits	32
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VEGFC_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.084586 (rank : 378)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	16
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VEGFC_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.055038 (rank : 488)
Query Neighborhood Hits	53	Target Neighborhood Hits	119	Shared Neighborhood Hits	17
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VLDLR_HUMAN
θ value	θ > 10 (rank : 525)	NC score	0.139284 (rank : 274)
Query Neighborhood Hits	53	Target Neighborhood Hits	383	Shared Neighborhood Hits	27
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.132348 (rank : 291)
Query Neighborhood Hits	53	Target Neighborhood Hits	360	Shared Neighborhood Hits	25
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WFDC2_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.057348 (rank : 466)
Query Neighborhood Hits	53	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

WFDC5_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.051790 (rank : 519)
Query Neighborhood Hits	53	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

WIF1_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.260284 (rank : 106)
Query Neighborhood Hits	53	Target Neighborhood Hits	392	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.262099 (rank : 100)
Query Neighborhood Hits	53	Target Neighborhood Hits	393	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WISP1_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.074304 (rank : 399)
Query Neighborhood Hits	53	Target Neighborhood Hits	121	Shared Neighborhood Hits	21
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

WISP1_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.071570 (rank : 412)
Query Neighborhood Hits	53	Target Neighborhood Hits	123	Shared Neighborhood Hits	20
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

WISP2_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.115325 (rank : 324)
Query Neighborhood Hits	53	Target Neighborhood Hits	126	Shared Neighborhood Hits	21
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.105088 (rank : 348)
Query Neighborhood Hits	53	Target Neighborhood Hits	129	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

WISP3_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.069289 (rank : 418)
Query Neighborhood Hits	53	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

XLKD1_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.051707 (rank : 521)
Query Neighborhood Hits	53	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5Y7, Q8TC18, Q9UNF4	Gene names	XLKD1, CRSBP1, HAR
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Hyaluronic acid receptor) (Extracellular link domain-containing protein 1).

XLKD1_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.051570 (rank : 523)
Query Neighborhood Hits	53	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHC0, Q3TUC1, Q99NE4	Gene names	Xlkd1, Crsbp1
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1).

Hits sorted by NC score

LCE1E_HUMAN
NC score	0.999962 (rank : 1)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1C_HUMAN
NC score	0.917766 (rank : 2)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	53	Target Neighborhood Hits	65	Shared Neighborhood Hits	51
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1F_HUMAN
NC score	0.887703 (rank : 3)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	53	Target Neighborhood Hits	48	Shared Neighborhood Hits	43
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE1B_HUMAN
NC score	0.867264 (rank : 4)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	53	Target Neighborhood Hits	58	Shared Neighborhood Hits	43
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1A_HUMAN
NC score	0.802438 (rank : 5)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	40
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1D_HUMAN
NC score	0.788249 (rank : 6)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	53	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE5A_HUMAN
NC score	0.590797 (rank : 7)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	53	Target Neighborhood Hits	43	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LCE2D_HUMAN
NC score	0.535633 (rank : 8)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	53	Target Neighborhood Hits	50	Shared Neighborhood Hits	28
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE2C_HUMAN
NC score	0.529739 (rank : 9)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2A_HUMAN
NC score	0.507091 (rank : 10)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	53	Target Neighborhood Hits	50	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
NC score	0.495944 (rank : 11)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	53	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE3A_HUMAN
NC score	0.457580 (rank : 12)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	53	Target Neighborhood Hits	29	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

MCSP_MOUSE
NC score	0.456257 (rank : 13)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	53	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

SPR2D_MOUSE
NC score	0.429285 (rank : 14)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	53	Target Neighborhood Hits	61	Shared Neighborhood Hits	23
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

GRN_MOUSE
NC score	0.422989 (rank : 15)	θ value	0.0431538 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	248	Shared Neighborhood Hits	30
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

GRN_HUMAN
NC score	0.416691 (rank : 16)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	268	Shared Neighborhood Hits	33
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KR511_HUMAN
NC score	0.402065 (rank : 17)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	53	Target Neighborhood Hits	231	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KR171_HUMAN
NC score	0.399869 (rank : 18)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	53	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA53_HUMAN
NC score	0.394603 (rank : 19)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	53	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

SPR2I_MOUSE
NC score	0.392107 (rank : 20)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	53	Target Neighborhood Hits	45	Shared Neighborhood Hits	19
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SPR2G_MOUSE
NC score	0.391051 (rank : 21)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	21
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2F_HUMAN
NC score	0.390030 (rank : 22)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	53	Target Neighborhood Hits	33	Shared Neighborhood Hits	17
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2H_MOUSE
NC score	0.387374 (rank : 23)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	53	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

KRA56_HUMAN
NC score	0.380922 (rank : 24)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	53	Target Neighborhood Hits	207	Shared Neighborhood Hits	34
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LCE4A_HUMAN
NC score	0.380160 (rank : 25)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	53	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

KRA51_HUMAN
NC score	0.378540 (rank : 26)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	34
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KR104_HUMAN
NC score	0.378168 (rank : 27)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	53	Target Neighborhood Hits	313	Shared Neighborhood Hits	36
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

SPR2E_MOUSE
NC score	0.377395 (rank : 28)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	53	Target Neighborhood Hits	45	Shared Neighborhood Hits	18
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

KRA58_HUMAN
NC score	0.374371 (rank : 29)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	53	Target Neighborhood Hits	324	Shared Neighborhood Hits	37
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

SPR2B_MOUSE
NC score	0.373560 (rank : 30)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	53	Target Neighborhood Hits	51	Shared Neighborhood Hits	23
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

KR107_HUMAN
NC score	0.371371 (rank : 31)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	53	Target Neighborhood Hits	330	Shared Neighborhood Hits	39
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR101_HUMAN
NC score	0.369536 (rank : 32)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	53	Target Neighborhood Hits	261	Shared Neighborhood Hits	37
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KRA54_HUMAN
NC score	0.368327 (rank : 33)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	53	Target Neighborhood Hits	270	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

SPR2F_MOUSE
NC score	0.368233 (rank : 34)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	53	Target Neighborhood Hits	43	Shared Neighborhood Hits	18
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

KRA57_HUMAN
NC score	0.362628 (rank : 35)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	53	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

SPR2E_HUMAN
NC score	0.360920 (rank : 36)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	53	Target Neighborhood Hits	32	Shared Neighborhood Hits	15
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

KR106_HUMAN
NC score	0.358545 (rank : 37)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	53	Target Neighborhood Hits	347	Shared Neighborhood Hits	37
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KRA55_HUMAN
NC score	0.357150 (rank : 38)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	53	Target Neighborhood Hits	257	Shared Neighborhood Hits	34
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

SREC_HUMAN
NC score	0.357011 (rank : 39)	θ value	0.0431538 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	645	Shared Neighborhood Hits	36
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ZAN_MOUSE
NC score	0.356519 (rank : 40)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	808	Shared Neighborhood Hits	38
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KRA59_HUMAN
NC score	0.348895 (rank : 41)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	53	Target Neighborhood Hits	310	Shared Neighborhood Hits	36
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

SREC2_HUMAN
NC score	0.348342 (rank : 42)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	645	Shared Neighborhood Hits	38
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
NC score	0.345393 (rank : 43)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	605	Shared Neighborhood Hits	38
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KR510_HUMAN
NC score	0.345276 (rank : 44)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	53	Target Neighborhood Hits	217	Shared Neighborhood Hits	36
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR102_HUMAN
NC score	0.341738 (rank : 45)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	53	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR109_HUMAN
NC score	0.340752 (rank : 46)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	53	Target Neighborhood Hits	226	Shared Neighborhood Hits	34
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR108_HUMAN
NC score	0.339799 (rank : 47)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	53	Target Neighborhood Hits	226	Shared Neighborhood Hits	36
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR105_HUMAN
NC score	0.335717 (rank : 48)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	53	Target Neighborhood Hits	271	Shared Neighborhood Hits	35
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KRA52_HUMAN
NC score	0.331933 (rank : 49)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	53	Target Neighborhood Hits	236	Shared Neighborhood Hits	33
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

MEGF6_HUMAN
NC score	0.324370 (rank : 50)	θ value	0.0148317 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	671	Shared Neighborhood Hits	45
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

SPR2D_HUMAN
NC score	0.321161 (rank : 51)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	53	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	P22532, Q5T523, Q96RM3	Gene names	SPRR2D
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D (SPR-2D) (Small proline-rich protein II) (SPR-II).

KRA98_HUMAN
NC score	0.316205 (rank : 52)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	53	Target Neighborhood Hits	185	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

HTRA3_MOUSE
NC score	0.316147 (rank : 53)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	156	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

KR10C_HUMAN
NC score	0.309875 (rank : 54)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	53	Target Neighborhood Hits	219	Shared Neighborhood Hits	33
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

HTRA1_HUMAN
NC score	0.309405 (rank : 55)	θ value	0.0193708 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	155	Shared Neighborhood Hits	14
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

KR10B_HUMAN
NC score	0.308841 (rank : 56)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	53	Target Neighborhood Hits	269	Shared Neighborhood Hits	34
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

HTRA4_HUMAN
NC score	0.308268 (rank : 57)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	119	Shared Neighborhood Hits	7
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

HTRA3_HUMAN
NC score	0.305358 (rank : 58)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA1_MOUSE
NC score	0.303293 (rank : 59)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	140	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

KRA13_HUMAN
NC score	0.300208 (rank : 60)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	53	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA92_HUMAN
NC score	0.299923 (rank : 61)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	53	Target Neighborhood Hits	198	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA47_HUMAN
NC score	0.295047 (rank : 62)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	53	Target Neighborhood Hits	204	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA45_HUMAN
NC score	0.290577 (rank : 63)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	53	Target Neighborhood Hits	194	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

ESM1_HUMAN
NC score	0.290138 (rank : 64)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	53	Target Neighborhood Hits	110	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

STAB1_MOUSE
NC score	0.288634 (rank : 65)	θ value	0.0193708 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	566	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB1_HUMAN
NC score	0.286923 (rank : 66)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	546	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

NOTC4_HUMAN
NC score	0.286884 (rank : 67)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	905	Shared Neighborhood Hits	35
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

KRA93_HUMAN
NC score	0.285137 (rank : 68)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	53	Target Neighborhood Hits	203	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA15_HUMAN
NC score	0.283465 (rank : 69)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	53	Target Neighborhood Hits	126	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA99_HUMAN
NC score	0.283248 (rank : 70)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	53	Target Neighborhood Hits	173	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

NOTC4_MOUSE
NC score	0.283081 (rank : 71)	θ value	0.00869519 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	872	Shared Neighborhood Hits	35
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

KRA44_HUMAN
NC score	0.282490 (rank : 72)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	53	Target Neighborhood Hits	162	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

CRIM1_HUMAN
NC score	0.282191 (rank : 73)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	362	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

JAG2_MOUSE
NC score	0.281192 (rank : 74)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	53	Target Neighborhood Hits	504	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

JAG2_HUMAN
NC score	0.280768 (rank : 75)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	491	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

KR412_HUMAN
NC score	0.280432 (rank : 76)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	53	Target Neighborhood Hits	178	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

STAB2_MOUSE
NC score	0.278737 (rank : 77)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	53	Target Neighborhood Hits	528	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STAB2_HUMAN
NC score	0.278035 (rank : 78)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	534	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

NOTC3_MOUSE
NC score	0.275314 (rank : 79)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	975	Shared Neighborhood Hits	34
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

JAG1_HUMAN
NC score	0.275290 (rank : 80)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	53	Target Neighborhood Hits	514	Shared Neighborhood Hits	33
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

ZAN_HUMAN
NC score	0.275168 (rank : 81)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	679	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

HTRA2_MOUSE
NC score	0.274901 (rank : 82)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	53	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

NOTC1_MOUSE
NC score	0.274392 (rank : 83)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	53	Target Neighborhood Hits	916	Shared Neighborhood Hits	34
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

HTRA2_HUMAN
NC score	0.274056 (rank : 84)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	53	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

JAG1_MOUSE
NC score	0.273833 (rank : 85)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	53	Target Neighborhood Hits	518	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NOTC3_HUMAN
NC score	0.273651 (rank : 86)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	53	Target Neighborhood Hits	1062	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_MOUSE
NC score	0.273356 (rank : 87)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	1069	Shared Neighborhood Hits	34
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KRA94_HUMAN
NC score	0.270884 (rank : 88)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	53	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

SPR2K_MOUSE
NC score	0.270770 (rank : 89)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	53	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	O70562	Gene names	Sprr2k
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2K.

NOTC1_HUMAN
NC score	0.270403 (rank : 90)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	53	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DLL3_HUMAN
NC score	0.269671 (rank : 91)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	419	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
NC score	0.268795 (rank : 92)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	53	Target Neighborhood Hits	399	Shared Neighborhood Hits	30
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

NOTC2_HUMAN
NC score	0.267707 (rank : 93)	θ value	0.0252991 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	1113	Shared Neighborhood Hits	35
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KR414_HUMAN
NC score	0.265614 (rank : 94)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	53	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

VWF_MOUSE
NC score	0.265250 (rank : 95)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	381	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

NAGPA_MOUSE
NC score	0.264437 (rank : 96)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	53	Target Neighborhood Hits	308	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

SPR2B_HUMAN
NC score	0.264381 (rank : 97)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	53	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	P35325, Q5T528	Gene names	SPRR2B
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B (SPR-2B).

VWF_HUMAN
NC score	0.264359 (rank : 98)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	396	Shared Neighborhood Hits	36
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KRA11_HUMAN
NC score	0.263338 (rank : 99)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	53	Target Neighborhood Hits	155	Shared Neighborhood Hits	24
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

WIF1_MOUSE
NC score	0.262099 (rank : 100)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	53	Target Neighborhood Hits	393	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

SSPO_MOUSE
NC score	0.262077 (rank : 101)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	800	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

NAGPA_HUMAN
NC score	0.261577 (rank : 102)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	53	Target Neighborhood Hits	282	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

ESM1_MOUSE
NC score	0.261531 (rank : 103)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	53	Target Neighborhood Hits	107	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

DLL4_MOUSE
NC score	0.261392 (rank : 104)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	53	Target Neighborhood Hits	440	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

SPR2G_HUMAN
NC score	0.260609 (rank : 105)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	53	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYE4	Gene names	SPRR2G
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G (SPR-2G).

WIF1_HUMAN
NC score	0.260284 (rank : 106)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	53	Target Neighborhood Hits	392	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

DLL4_HUMAN
NC score	0.260142 (rank : 107)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	53	Target Neighborhood Hits	435	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

MUC5B_HUMAN
NC score	0.257342 (rank : 108)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	1020	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

DLK_HUMAN
NC score	0.256035 (rank : 109)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	53	Target Neighborhood Hits	401	Shared Neighborhood Hits	33
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

KR103_HUMAN
NC score	0.254844 (rank : 110)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	212	Shared Neighborhood Hits	32
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

EGFL9_MOUSE
NC score	0.253453 (rank : 111)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	53	Target Neighborhood Hits	379	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGFL9_HUMAN
NC score	0.253291 (rank : 112)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	53	Target Neighborhood Hits	365	Shared Neighborhood Hits	29
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

DLK_MOUSE
NC score	0.252858 (rank : 113)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	53	Target Neighborhood Hits	374	Shared Neighborhood Hits	27
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

AGRIN_HUMAN
NC score	0.250885 (rank : 114)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	53	Target Neighborhood Hits	582	Shared Neighborhood Hits	41
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

DLL1_MOUSE
NC score	0.250168 (rank : 115)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	53	Target Neighborhood Hits	456	Shared Neighborhood Hits	31
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DNER_HUMAN
NC score	0.249415 (rank : 116)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	53	Target Neighborhood Hits	460	Shared Neighborhood Hits	30
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DLL1_HUMAN
NC score	0.249370 (rank : 117)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	53	Target Neighborhood Hits	455	Shared Neighborhood Hits	32
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

CRUM2_HUMAN
NC score	0.249047 (rank : 118)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	53	Target Neighborhood Hits	453	Shared Neighborhood Hits	30
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

TENX_HUMAN
NC score	0.248573 (rank : 119)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	789	Shared Neighborhood Hits	35
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

NFX1_HUMAN
NC score	0.246147 (rank : 120)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	53	Target Neighborhood Hits	405	Shared Neighborhood Hits	32
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NELL1_HUMAN
NC score	0.245364 (rank : 121)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	53	Target Neighborhood Hits	451	Shared Neighborhood Hits	33
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

DNER_MOUSE
NC score	0.242996 (rank : 122)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	53	Target Neighborhood Hits	413	Shared Neighborhood Hits	27
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

SPR2A_HUMAN
NC score	0.241987 (rank : 123)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	53	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	P35326	Gene names	SPRR2A
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A (SPR-2A) (2-1).

FBN3_HUMAN
NC score	0.236312 (rank : 124)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	53	Target Neighborhood Hits	543	Shared Neighborhood Hits	36
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

CRUM1_MOUSE
NC score	0.233839 (rank : 125)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	53	Target Neighborhood Hits	444	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

TENA_HUMAN
NC score	0.233832 (rank : 126)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	53	Target Neighborhood Hits	631	Shared Neighborhood Hits	36
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LTBP4_MOUSE
NC score	0.233141 (rank : 127)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	53	Target Neighborhood Hits	607	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NELL2_MOUSE
NC score	0.233031 (rank : 128)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	53	Target Neighborhood Hits	436	Shared Neighborhood Hits	32
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

FRAS1_MOUSE
NC score	0.232207 (rank : 129)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	747	Shared Neighborhood Hits	37
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NELL2_HUMAN
NC score	0.231536 (rank : 130)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	53	Target Neighborhood Hits	449	Shared Neighborhood Hits	32
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

CRUM1_HUMAN
NC score	0.230209 (rank : 131)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	53	Target Neighborhood Hits	457	Shared Neighborhood Hits	27
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FBN2_HUMAN
NC score	0.228879 (rank : 132)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	53	Target Neighborhood Hits	560	Shared Neighborhood Hits	33
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_HUMAN
NC score	0.228509 (rank : 133)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	53	Target Neighborhood Hits	557	Shared Neighborhood Hits	33
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

KR10A_HUMAN
NC score	0.228442 (rank : 134)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	53	Target Neighborhood Hits	232	Shared Neighborhood Hits	31
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

FBN2_MOUSE
NC score	0.227774 (rank : 135)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	53	Target Neighborhood Hits	549	Shared Neighborhood Hits	34
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FRAS1_HUMAN
NC score	0.226918 (rank : 136)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	53	Target Neighborhood Hits	759	Shared Neighborhood Hits	38
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KR410_HUMAN
NC score	0.226889 (rank : 137)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	53	Target Neighborhood Hits	156	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

FBN1_MOUSE
NC score	0.226795 (rank : 138)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	53	Target Neighborhood Hits	563	Shared Neighborhood Hits	34
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

TENA_MOUSE
NC score	0.224077 (rank : 139)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	53	Target Neighborhood Hits	596	Shared Neighborhood Hits	32
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

LORI_MOUSE
NC score	0.221951 (rank : 140)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

PCSK5_MOUSE
NC score	0.219719 (rank : 141)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	53	Target Neighborhood Hits	613	Shared Neighborhood Hits	38
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TECTA_MOUSE
NC score	0.217045 (rank : 142)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	53	Target Neighborhood Hits	244	Shared Neighborhood Hits	29
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

LTBP2_HUMAN
NC score	0.216615 (rank : 143)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	53	Target Neighborhood Hits	552	Shared Neighborhood Hits	34
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LCE3C_HUMAN
NC score	0.216427 (rank : 144)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	53	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

BMPER_MOUSE
NC score	0.216135 (rank : 145)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	53	Target Neighborhood Hits	194	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

LTBP3_HUMAN
NC score	0.214123 (rank : 146)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	53	Target Neighborhood Hits	502	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LAMA5_HUMAN
NC score	0.211939 (rank : 147)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	53	Target Neighborhood Hits	976	Shared Neighborhood Hits	37
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

TECTA_HUMAN
NC score	0.211345 (rank : 148)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	239	Shared Neighborhood Hits	27
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

LTBP2_MOUSE
NC score	0.210282 (rank : 149)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	53	Target Neighborhood Hits	617	Shared Neighborhood Hits	31
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

BMPER_HUMAN
NC score	0.209567 (rank : 150)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	53	Target Neighborhood Hits	175	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

MCSP_HUMAN
NC score	0.209220 (rank : 151)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	53	Target Neighborhood Hits	48	Shared Neighborhood Hits	12
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

LTBP3_MOUSE
NC score	0.209086 (rank : 152)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	53	Target Neighborhood Hits	475	Shared Neighborhood Hits	32
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MUC2_HUMAN
NC score	0.206913 (rank : 153)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	53	Target Neighborhood Hits	906	Shared Neighborhood Hits	29
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

LTB1L_HUMAN
NC score	0.205745 (rank : 154)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	53	Target Neighborhood Hits	553	Shared Neighborhood Hits	31
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TRBM_HUMAN
NC score	0.205490 (rank : 155)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	53	Target Neighborhood Hits	339	Shared Neighborhood Hits	33
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LTB1S_HUMAN
NC score	0.204983 (rank : 156)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	53	Target Neighborhood Hits	502	Shared Neighborhood Hits	30
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LAMA5_MOUSE
NC score	0.204192 (rank : 157)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	53	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MEGF8_HUMAN
NC score	0.203779 (rank : 158)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	528	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
NC score	0.203193 (rank : 159)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	53	Target Neighborhood Hits	520	Shared Neighborhood Hits	29
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

EGFL7_HUMAN
NC score	0.202837 (rank : 160)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	53	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

LTB1S_MOUSE
NC score	0.202796 (rank : 161)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	53	Target Neighborhood Hits	479	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.202038 (rank : 162)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	53	Target Neighborhood Hits	514	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ZNFX1_HUMAN
NC score	0.201399 (rank : 163)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	308	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
NC score	0.200224 (rank : 164)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	407	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

FBLN2_HUMAN
NC score	0.199756 (rank : 165)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	53	Target Neighborhood Hits	392	Shared Neighborhood Hits	28
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LAMB2_HUMAN
NC score	0.198005 (rank : 166)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	53	Target Neighborhood Hits	692	Shared Neighborhood Hits	29
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

EGFL7_MOUSE
NC score	0.197899 (rank : 167)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	53	Target Neighborhood Hits	287	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

CUBN_HUMAN
NC score	0.196726 (rank : 168)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	53	Target Neighborhood Hits	482	Shared Neighborhood Hits	30
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

UROM_HUMAN
NC score	0.196395 (rank : 169)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	53	Target Neighborhood Hits	284	Shared Neighborhood Hits	28
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

LAMB2_MOUSE
NC score	0.196349 (rank : 170)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	53	Target Neighborhood Hits	722	Shared Neighborhood Hits	30
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

CREL1_HUMAN
NC score	0.195936 (rank : 171)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	53	Target Neighborhood Hits	441	Shared Neighborhood Hits	28
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

TRBM_MOUSE
NC score	0.195306 (rank : 172)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	361	Shared Neighborhood Hits	31
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

SCUB3_MOUSE
NC score	0.193534 (rank : 173)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	53	Target Neighborhood Hits	442	Shared Neighborhood Hits	30
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

FBLN1_HUMAN
NC score	0.193128 (rank : 174)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	53	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
NC score	0.193059 (rank : 175)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	53	Target Neighborhood Hits	329	Shared Neighborhood Hits	31
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

SCUB3_HUMAN
NC score	0.192594 (rank : 176)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	53	Target Neighborhood Hits	428	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

CUBN_MOUSE
NC score	0.191080 (rank : 177)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	53	Target Neighborhood Hits	477	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

FBLN2_MOUSE
NC score	0.190797 (rank : 178)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	53	Target Neighborhood Hits	505	Shared Neighborhood Hits	30
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

CREL1_MOUSE
NC score	0.188730 (rank : 179)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	53	Target Neighborhood Hits	524	Shared Neighborhood Hits	30
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MEGF9_HUMAN
NC score	0.188519 (rank : 180)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	53	Target Neighborhood Hits	557	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

WFDC3_HUMAN
NC score	0.182071 (rank : 181)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	138	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

MATN2_MOUSE
NC score	0.181969 (rank : 182)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	53	Target Neighborhood Hits	356	Shared Neighborhood Hits	31
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

SPR1B_HUMAN
NC score	0.181863 (rank : 183)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	P22528, P22529, P22530, Q5T524	Gene names	SPRR1B
Domain Architecture	No domain graphic available
Description	Cornifin B (Small proline-rich protein IB) (SPR-IB) (14.9 kDa pancornulin).

HHIP_HUMAN
NC score	0.181302 (rank : 184)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	53	Target Neighborhood Hits	249	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LRP1_HUMAN
NC score	0.180012 (rank : 185)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	53	Target Neighborhood Hits	617	Shared Neighborhood Hits	35
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MEGF9_MOUSE
NC score	0.179561 (rank : 186)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	53	Target Neighborhood Hits	896	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

EDIL3_MOUSE
NC score	0.178966 (rank : 187)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	53	Target Neighborhood Hits	317	Shared Neighborhood Hits	24
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LAMC3_HUMAN
NC score	0.177873 (rank : 188)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	53	Target Neighborhood Hits	588	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMB1_MOUSE
NC score	0.177376 (rank : 189)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	53	Target Neighborhood Hits	919	Shared Neighborhood Hits	30
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

UROM_MOUSE
NC score	0.177035 (rank : 190)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	53	Target Neighborhood Hits	276	Shared Neighborhood Hits	27
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

EGFL8_HUMAN
NC score	0.176795 (rank : 191)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	53	Target Neighborhood Hits	270	Shared Neighborhood Hits	21
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

LAMA1_MOUSE
NC score	0.176395 (rank : 192)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	53	Target Neighborhood Hits	838	Shared Neighborhood Hits	35
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

C1QR1_HUMAN
NC score	0.175861 (rank : 193)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	53	Target Neighborhood Hits	493	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

MATN2_HUMAN
NC score	0.175717 (rank : 194)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	53	Target Neighborhood Hits	365	Shared Neighborhood Hits	29
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

LAMA1_HUMAN
NC score	0.175034 (rank : 195)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	53	Target Neighborhood Hits	804	Shared Neighborhood Hits	34
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

KRA42_HUMAN
NC score	0.174886 (rank : 196)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	53	Target Neighborhood Hits	149	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

C1QR1_MOUSE
NC score	0.174272 (rank : 197)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	53	Target Neighborhood Hits	342	Shared Neighborhood Hits	26
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

SPR1A_HUMAN
NC score	0.173648 (rank : 198)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

LRP1B_HUMAN
NC score	0.173577 (rank : 199)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	53	Target Neighborhood Hits	602	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LAMA2_HUMAN
NC score	0.173187 (rank : 200)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	53	Target Neighborhood Hits	1092	Shared Neighborhood Hits	33
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC3_MOUSE
NC score	0.172720 (rank : 201)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	53	Target Neighborhood Hits	624	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

EDIL3_HUMAN
NC score	0.172694 (rank : 202)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	53	Target Neighborhood Hits	292	Shared Neighborhood Hits	23
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

HHIP_MOUSE
NC score	0.170859 (rank : 203)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	53	Target Neighborhood Hits	219	Shared Neighborhood Hits	20
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LAMB1_HUMAN
NC score	0.170853 (rank : 204)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	53	Target Neighborhood Hits	1018	Shared Neighborhood Hits	29
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

NID2_HUMAN
NC score	0.170732 (rank : 205)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	53	Target Neighborhood Hits	456	Shared Neighborhood Hits	30
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

FBLN4_HUMAN
NC score	0.170515 (rank : 206)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	53	Target Neighborhood Hits	278	Shared Neighborhood Hits	28
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

NID2_MOUSE
NC score	0.169711 (rank : 207)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	53	Target Neighborhood Hits	338	Shared Neighborhood Hits	28
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

LRP1B_MOUSE
NC score	0.169689 (rank : 208)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	53	Target Neighborhood Hits	606	Shared Neighborhood Hits	34
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LCE3B_HUMAN
NC score	0.168785 (rank : 209)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

EGFL8_MOUSE
NC score	0.168043 (rank : 210)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	53	Target Neighborhood Hits	266	Shared Neighborhood Hits	19
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

FBLN5_HUMAN
NC score	0.167294 (rank : 211)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	53	Target Neighborhood Hits	329	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

USH2A_MOUSE
NC score	0.166523 (rank : 212)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	53	Target Neighborhood Hits	626	Shared Neighborhood Hits	32
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LAMB3_MOUSE
NC score	0.166426 (rank : 213)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	53	Target Neighborhood Hits	444	Shared Neighborhood Hits	27
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

FBLN5_MOUSE
NC score	0.166316 (rank : 214)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	53	Target Neighborhood Hits	317	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

GAS6_HUMAN
NC score	0.165427 (rank : 215)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	53	Target Neighborhood Hits	348	Shared Neighborhood Hits	24
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN4_MOUSE
NC score	0.165218 (rank : 216)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	53	Target Neighborhood Hits	270	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

LAMC2_MOUSE
NC score	0.165196 (rank : 217)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	53	Target Neighborhood Hits	614	Shared Neighborhood Hits	31
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMA2_MOUSE
NC score	0.164459 (rank : 218)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	53	Target Neighborhood Hits	1198	Shared Neighborhood Hits	33
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

EGF_MOUSE
NC score	0.163027 (rank : 219)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	53	Target Neighborhood Hits	358	Shared Neighborhood Hits	30
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

LAMB3_HUMAN
NC score	0.162510 (rank : 220)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	53	Target Neighborhood Hits	461	Shared Neighborhood Hits	27
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMC2_HUMAN
NC score	0.161257 (rank : 221)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	53	Target Neighborhood Hits	715	Shared Neighborhood Hits	26
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

SLIT1_HUMAN
NC score	0.160385 (rank : 222)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	53	Target Neighborhood Hits	700	Shared Neighborhood Hits	29
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

ITB4_HUMAN
NC score	0.158792 (rank : 223)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	53	Target Neighborhood Hits	458	Shared Neighborhood Hits	29
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

PROS_HUMAN
NC score	0.158674 (rank : 224)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	53	Target Neighborhood Hits	340	Shared Neighborhood Hits	27
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

GAS6_MOUSE
NC score	0.158314 (rank : 225)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	53	Target Neighborhood Hits	343	Shared Neighborhood Hits	25
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ITB6_HUMAN
NC score	0.157922 (rank : 226)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	53	Target Neighborhood Hits	318	Shared Neighborhood Hits	28
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

KR413_HUMAN
NC score	0.157660 (rank : 227)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	53	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

ITB7_HUMAN
NC score	0.157341 (rank : 228)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	53	Target Neighborhood Hits	290	Shared Neighborhood Hits	29
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

FBLN3_HUMAN
NC score	0.156826 (rank : 229)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	53	Target Neighborhood Hits	293	Shared Neighborhood Hits	25
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

PROS_MOUSE
NC score	0.156549 (rank : 230)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	53	Target Neighborhood Hits	330	Shared Neighborhood Hits	28
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

ITB6_MOUSE
NC score	0.155182 (rank : 231)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	53	Target Neighborhood Hits	341	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMC1_MOUSE
NC score	0.155147 (rank : 232)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	53	Target Neighborhood Hits	856	Shared Neighborhood Hits	26
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SLIT2_HUMAN
NC score	0.154780 (rank : 233)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	53	Target Neighborhood Hits	708	Shared Neighborhood Hits	31
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

MFGM_MOUSE
NC score	0.153993 (rank : 234)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	53	Target Neighborhood Hits	233	Shared Neighborhood Hits	20
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

SLIT3_MOUSE
NC score	0.153765 (rank : 235)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	53	Target Neighborhood Hits	700	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

FBLN3_MOUSE
NC score	0.153713 (rank : 236)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	53	Target Neighborhood Hits	279	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

NID1_MOUSE
NC score	0.152970 (rank : 237)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	53	Target Neighborhood Hits	335	Shared Neighborhood Hits	23
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SLIT3_HUMAN
NC score	0.152382 (rank : 238)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	53	Target Neighborhood Hits	682	Shared Neighborhood Hits	27
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT2_MOUSE
NC score	0.152356 (rank : 239)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	53	Target Neighborhood Hits	684	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ITB7_MOUSE
NC score	0.151381 (rank : 240)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	53	Target Neighborhood Hits	277	Shared Neighborhood Hits	26
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

SLIT1_MOUSE
NC score	0.150806 (rank : 241)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	53	Target Neighborhood Hits	715	Shared Neighborhood Hits	28
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

ITB2_HUMAN
NC score	0.150784 (rank : 242)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	53	Target Neighborhood Hits	282	Shared Neighborhood Hits	28
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
NC score	0.150411 (rank : 243)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	53	Target Neighborhood Hits	326	Shared Neighborhood Hits	30
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB5_MOUSE
NC score	0.150237 (rank : 244)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	53	Target Neighborhood Hits	329	Shared Neighborhood Hits	30
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

SPR1A_MOUSE
NC score	0.149715 (rank : 245)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TENR_HUMAN
NC score	0.149537 (rank : 246)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	53	Target Neighborhood Hits	526	Shared Neighborhood Hits	27
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

USH2A_HUMAN
NC score	0.148751 (rank : 247)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	53	Target Neighborhood Hits	600	Shared Neighborhood Hits	26
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

LAMC1_HUMAN
NC score	0.148402 (rank : 248)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	53	Target Neighborhood Hits	922	Shared Neighborhood Hits	30
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TENR_MOUSE
NC score	0.148077 (rank : 249)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	53	Target Neighborhood Hits	531	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

CD248_HUMAN
NC score	0.147024 (rank : 250)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	53	Target Neighborhood Hits	679	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

EMR1_HUMAN
NC score	0.146566 (rank : 251)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	53	Target Neighborhood Hits	382	Shared Neighborhood Hits	25
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

ITB3_HUMAN
NC score	0.146364 (rank : 252)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	53	Target Neighborhood Hits	325	Shared Neighborhood Hits	26
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

NID1_HUMAN
NC score	0.146343 (rank : 253)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	53	Target Neighborhood Hits	329	Shared Neighborhood Hits	24
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

IBP7_HUMAN
NC score	0.146251 (rank : 254)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	53	Target Neighborhood Hits	220	Shared Neighborhood Hits	11
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

LRP2_HUMAN
NC score	0.145716 (rank : 255)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	53	Target Neighborhood Hits	573	Shared Neighborhood Hits	33
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ITB3_MOUSE
NC score	0.145685 (rank : 256)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	53	Target Neighborhood Hits	319	Shared Neighborhood Hits	28
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

COMP_MOUSE
NC score	0.145665 (rank : 257)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	53	Target Neighborhood Hits	290	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NTNG2_HUMAN
NC score	0.144161 (rank : 258)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	53	Target Neighborhood Hits	276	Shared Neighborhood Hits	26
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TENN_MOUSE
NC score	0.143091 (rank : 259)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	53	Target Neighborhood Hits	484	Shared Neighborhood Hits	28
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

NTNG2_MOUSE
NC score	0.143032 (rank : 260)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	53	Target Neighborhood Hits	276	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

CFC1_HUMAN
NC score	0.142619 (rank : 261)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	53	Target Neighborhood Hits	148	Shared Neighborhood Hits	17
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

EGF_HUMAN
NC score	0.142617 (rank : 262)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	53	Target Neighborhood Hits	343	Shared Neighborhood Hits	29
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

RECK_HUMAN
NC score	0.142369 (rank : 263)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	53	Target Neighborhood Hits	189	Shared Neighborhood Hits	25
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

CSPG2_MOUSE
NC score	0.142292 (rank : 264)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	53	Target Neighborhood Hits	711	Shared Neighborhood Hits	23
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

ATRN_HUMAN
NC score	0.142138 (rank : 265)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	53	Target Neighborhood Hits	525	Shared Neighborhood Hits	25
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

CD248_MOUSE
NC score	0.141769 (rank : 266)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	53	Target Neighborhood Hits	578	Shared Neighborhood Hits	25
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

IBP7_MOUSE
NC score	0.141521 (rank : 267)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	53	Target Neighborhood Hits	230	Shared Neighborhood Hits	13
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

LAMA3_MOUSE
NC score	0.141394 (rank : 268)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	53	Target Neighborhood Hits	859	Shared Neighborhood Hits	30
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

MT3_HUMAN
NC score	0.141225 (rank : 269)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	53	Target Neighborhood Hits	82	Shared Neighborhood Hits	12
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

ITB5_HUMAN
NC score	0.141151 (rank : 270)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	53	Target Neighborhood Hits	310	Shared Neighborhood Hits	26
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

TSP4_MOUSE
NC score	0.140352 (rank : 271)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	53	Target Neighborhood Hits	276	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

KRA24_HUMAN
NC score	0.140345 (rank : 272)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	192	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

CSPG2_HUMAN
NC score	0.139954 (rank : 273)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	53	Target Neighborhood Hits	681	Shared Neighborhood Hits	23
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

VLDLR_HUMAN
NC score	0.139284 (rank : 274)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	53	Target Neighborhood Hits	383	Shared Neighborhood Hits	27
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

MATN4_HUMAN
NC score	0.139110 (rank : 275)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	53	Target Neighborhood Hits	287	Shared Neighborhood Hits	29
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

RECK_MOUSE
NC score	0.139075 (rank : 276)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	53	Target Neighborhood Hits	158	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

SPR1B_MOUSE
NC score	0.139069 (rank : 277)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	395	Shared Neighborhood Hits	9
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

EMR1_MOUSE
NC score	0.138981 (rank : 278)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	53	Target Neighborhood Hits	349	Shared Neighborhood Hits	24
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

LDLR_HUMAN
NC score	0.138790 (rank : 279)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	53	Target Neighborhood Hits	375	Shared Neighborhood Hits	29
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP8_MOUSE
NC score	0.138722 (rank : 280)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	53	Target Neighborhood Hits	385	Shared Neighborhood Hits	28
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_HUMAN
NC score	0.137692 (rank : 281)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	53	Target Neighborhood Hits	346	Shared Neighborhood Hits	28
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

TENN_HUMAN
NC score	0.137460 (rank : 282)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	53	Target Neighborhood Hits	453	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

MATN3_HUMAN
NC score	0.134720 (rank : 283)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	53	Target Neighborhood Hits	268	Shared Neighborhood Hits	24
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

SUSD1_HUMAN
NC score	0.134658 (rank : 284)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	53	Target Neighborhood Hits	285	Shared Neighborhood Hits	19
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

ATRN_MOUSE
NC score	0.134579 (rank : 285)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	53	Target Neighborhood Hits	519	Shared Neighborhood Hits	26
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

COMP_HUMAN
NC score	0.133852 (rank : 286)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	53	Target Neighborhood Hits	258	Shared Neighborhood Hits	21
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CSPG3_HUMAN
NC score	0.133718 (rank : 287)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	53	Target Neighborhood Hits	676	Shared Neighborhood Hits	22
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
NC score	0.133649 (rank : 288)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	53	Target Neighborhood Hits	657	Shared Neighborhood Hits	22
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

SPRR3_MOUSE
NC score	0.133431 (rank : 289)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	53	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

TSP4_HUMAN
NC score	0.132800 (rank : 290)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	53	Target Neighborhood Hits	277	Shared Neighborhood Hits	21
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

VLDLR_MOUSE
NC score	0.132348 (rank : 291)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	53	Target Neighborhood Hits	360	Shared Neighborhood Hits	25
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

NTNG1_HUMAN
NC score	0.132070 (rank : 292)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	53	Target Neighborhood Hits	247	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

SPRR3_HUMAN
NC score	0.131111 (rank : 293)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

LDLR_MOUSE
NC score	0.130810 (rank : 294)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	53	Target Neighborhood Hits	382	Shared Neighborhood Hits	29
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MATN3_MOUSE
NC score	0.130780 (rank : 295)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	53	Target Neighborhood Hits	261	Shared Neighborhood Hits	25
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

TSP3_MOUSE
NC score	0.130731 (rank : 296)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	53	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

MT4_MOUSE
NC score	0.130186 (rank : 297)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	17
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ITB8_HUMAN
NC score	0.129793 (rank : 298)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	53	Target Neighborhood Hits	280	Shared Neighborhood Hits	26
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

NTNG1_MOUSE
NC score	0.129441 (rank : 299)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	53	Target Neighborhood Hits	246	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

TSP1_HUMAN
NC score	0.128822 (rank : 300)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	53	Target Neighborhood Hits	389	Shared Neighborhood Hits	28
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TDGF1_MOUSE
NC score	0.128766 (rank : 301)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	53	Target Neighborhood Hits	146	Shared Neighborhood Hits	17
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

SPRR4_HUMAN
NC score	0.128341 (rank : 302)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	53	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PI1, Q2M1Y7, Q5T522	Gene names	SPRR4
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 4.

TSP1_MOUSE
NC score	0.128122 (rank : 303)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	53	Target Neighborhood Hits	396	Shared Neighborhood Hits	28
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TEFF2_MOUSE
NC score	0.126450 (rank : 304)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	53	Target Neighborhood Hits	214	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.126392 (rank : 305)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	53	Target Neighborhood Hits	211	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TSP3_HUMAN
NC score	0.125883 (rank : 306)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	53	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TIE1_HUMAN
NC score	0.124836 (rank : 307)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	1241	Shared Neighborhood Hits	31
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

CD97_HUMAN
NC score	0.124498 (rank : 308)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	53	Target Neighborhood Hits	353	Shared Neighborhood Hits	21
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR2_HUMAN
NC score	0.124274 (rank : 309)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	53	Target Neighborhood Hits	345	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

ITB1_MOUSE
NC score	0.124061 (rank : 310)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	53	Target Neighborhood Hits	283	Shared Neighborhood Hits	24
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

CFC1_MOUSE
NC score	0.123444 (rank : 311)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	53	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

TIE1_MOUSE
NC score	0.123038 (rank : 312)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	1266	Shared Neighborhood Hits	32
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

SORL_MOUSE
NC score	0.122934 (rank : 313)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	53	Target Neighborhood Hits	439	Shared Neighborhood Hits	32
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

LAMA3_HUMAN
NC score	0.122735 (rank : 314)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	53	Target Neighborhood Hits	760	Shared Neighborhood Hits	25
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

PROZ_HUMAN
NC score	0.122692 (rank : 315)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	53	Target Neighborhood Hits	422	Shared Neighborhood Hits	23
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

ITB1_HUMAN
NC score	0.121973 (rank : 316)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	53	Target Neighborhood Hits	298	Shared Neighborhood Hits	25
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

SPR2A_MOUSE
NC score	0.121827 (rank : 317)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	53	Target Neighborhood Hits	35	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CQK8, O70553	Gene names	Sprr2a
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2A.

PROZ_MOUSE
NC score	0.121771 (rank : 318)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	53	Target Neighborhood Hits	410	Shared Neighborhood Hits	21
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

HMCN1_HUMAN
NC score	0.121092 (rank : 319)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	53	Target Neighborhood Hits	983	Shared Neighborhood Hits	32
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

LYAM3_MOUSE
NC score	0.119820 (rank : 320)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	53	Target Neighborhood Hits	390	Shared Neighborhood Hits	26
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LAMA4_MOUSE
NC score	0.118726 (rank : 321)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	53	Target Neighborhood Hits	584	Shared Neighborhood Hits	21
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

SPRR4_MOUSE
NC score	0.116880 (rank : 322)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	53	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGN8	Gene names	Sprr4
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 4.

KAZD1_HUMAN
NC score	0.116597 (rank : 323)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	53	Target Neighborhood Hits	248	Shared Neighborhood Hits	11
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

WISP2_HUMAN
NC score	0.115325 (rank : 324)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	53	Target Neighborhood Hits	126	Shared Neighborhood Hits	21
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

MATN4_MOUSE
NC score	0.114564 (rank : 325)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	53	Target Neighborhood Hits	277	Shared Neighborhood Hits	23
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

PGBM_MOUSE
NC score	0.114421 (rank : 326)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	53	Target Neighborhood Hits	1073	Shared Neighborhood Hits	32
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TSP2_MOUSE
NC score	0.113919 (rank : 327)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	53	Target Neighborhood Hits	352	Shared Neighborhood Hits	24
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

LAMA4_HUMAN
NC score	0.113829 (rank : 328)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	53	Target Neighborhood Hits	708	Shared Neighborhood Hits	21
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

CYR61_MOUSE
NC score	0.113535 (rank : 329)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	53	Target Neighborhood Hits	156	Shared Neighborhood Hits	24
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

PCSK5_HUMAN
NC score	0.113013 (rank : 330)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	53	Target Neighborhood Hits	291	Shared Neighborhood Hits	32
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

KR122_HUMAN
NC score	0.112694 (rank : 331)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	53	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

TSP2_HUMAN
NC score	0.112676 (rank : 332)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	53	Target Neighborhood Hits	359	Shared Neighborhood Hits	24
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

PCSK6_HUMAN
NC score	0.112651 (rank : 333)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	53	Target Neighborhood Hits	298	Shared Neighborhood Hits	32
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

CYR61_HUMAN
NC score	0.112343 (rank : 334)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	53	Target Neighborhood Hits	159	Shared Neighborhood Hits	24
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

LRP4_HUMAN
NC score	0.110987 (rank : 335)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	53	Target Neighborhood Hits	355	Shared Neighborhood Hits	25
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

PGBM_HUMAN
NC score	0.110977 (rank : 336)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	53	Target Neighborhood Hits	1113	Shared Neighborhood Hits	33
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LRP4_MOUSE
NC score	0.109712 (rank : 337)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	53	Target Neighborhood Hits	351	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

TDGF1_HUMAN
NC score	0.109584 (rank : 338)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	53	Target Neighborhood Hits	132	Shared Neighborhood Hits	15
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

FSTL3_MOUSE
NC score	0.109401 (rank : 339)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	53	Target Neighborhood Hits	152	Shared Neighborhood Hits	20
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

MT4_HUMAN
NC score	0.108289 (rank : 340)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	53	Target Neighborhood Hits	83	Shared Neighborhood Hits	13
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

CD97_MOUSE
NC score	0.107652 (rank : 341)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	53	Target Neighborhood Hits	295	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

TIE2_HUMAN
NC score	0.107616 (rank : 342)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	53	Target Neighborhood Hits	1192	Shared Neighborhood Hits	33
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TDGF2_HUMAN
NC score	0.107587 (rank : 343)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	53	Target Neighborhood Hits	131	Shared Neighborhood Hits	15
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

NET4_HUMAN
NC score	0.106488 (rank : 344)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	53	Target Neighborhood Hits	191	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

TIE2_MOUSE
NC score	0.106237 (rank : 345)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	53	Target Neighborhood Hits	1204	Shared Neighborhood Hits	34
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

NET4_MOUSE
NC score	0.105284 (rank : 346)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	53	Target Neighborhood Hits	180	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

ELTD1_MOUSE
NC score	0.105244 (rank : 347)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

WISP2_MOUSE
NC score	0.105088 (rank : 348)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	53	Target Neighborhood Hits	129	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

FSTL3_HUMAN
NC score	0.104170 (rank : 349)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	53	Target Neighborhood Hits	162	Shared Neighborhood Hits	21
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

SORL_HUMAN
NC score	0.103379 (rank : 350)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	53	Target Neighborhood Hits	440	Shared Neighborhood Hits	26
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

RSPO4_MOUSE
NC score	0.103315 (rank : 351)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	110	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

KAZD1_MOUSE
NC score	0.102253 (rank : 352)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	53	Target Neighborhood Hits	281	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

CTGF_HUMAN
NC score	0.101799 (rank : 353)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	25
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

LYAM2_HUMAN
NC score	0.101556 (rank : 354)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	53	Target Neighborhood Hits	394	Shared Neighborhood Hits	19
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

FATH_HUMAN
NC score	0.101521 (rank : 355)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	53	Target Neighborhood Hits	570	Shared Neighborhood Hits	24
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

RSPO4_HUMAN
NC score	0.100848 (rank : 356)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	53	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

HABP2_MOUSE
NC score	0.099322 (rank : 357)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	53	Target Neighborhood Hits	445	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

LYAM3_HUMAN
NC score	0.099049 (rank : 358)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	53	Target Neighborhood Hits	378	Shared Neighborhood Hits	22
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

HABP2_HUMAN
NC score	0.097522 (rank : 359)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	53	Target Neighborhood Hits	431	Shared Neighborhood Hits	21
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

CELR3_MOUSE
NC score	0.095221 (rank : 360)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	53	Target Neighborhood Hits	687	Shared Neighborhood Hits	28
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR3_HUMAN
NC score	0.095074 (rank : 361)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	53	Target Neighborhood Hits	680	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

NOV_HUMAN
NC score	0.092657 (rank : 362)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	21
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

APR3_MOUSE
NC score	0.092032 (rank : 363)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	53	Target Neighborhood Hits	61	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

LYAM2_MOUSE
NC score	0.091845 (rank : 364)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	53	Target Neighborhood Hits	420	Shared Neighborhood Hits	21
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NOV_MOUSE
NC score	0.091246 (rank : 365)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	53	Target Neighborhood Hits	130	Shared Neighborhood Hits	23
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

CELR2_HUMAN
NC score	0.089448 (rank : 366)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	53	Target Neighborhood Hits	657	Shared Neighborhood Hits	28
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

NET2_MOUSE
NC score	0.088889 (rank : 367)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	53	Target Neighborhood Hits	193	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

MT3_MOUSE
NC score	0.088550 (rank : 368)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	8
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

NET2_HUMAN
NC score	0.088043 (rank : 369)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	53	Target Neighborhood Hits	194	Shared Neighborhood Hits	21
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

RELN_MOUSE
NC score	0.087923 (rank : 370)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	53	Target Neighborhood Hits	235	Shared Neighborhood Hits	19
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

IBP1_MOUSE
NC score	0.087865 (rank : 371)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	53	Target Neighborhood Hits	97	Shared Neighborhood Hits	14
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

CELR1_HUMAN
NC score	0.087812 (rank : 372)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	53	Target Neighborhood Hits	613	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
NC score	0.087737 (rank : 373)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	53	Target Neighborhood Hits	617	Shared Neighborhood Hits	26
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

RELN_HUMAN
NC score	0.086783 (rank : 374)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	53	Target Neighborhood Hits	233	Shared Neighborhood Hits	19
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

PGCB_MOUSE
NC score	0.085595 (rank : 375)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	53	Target Neighborhood Hits	459	Shared Neighborhood Hits	15
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

LYAM1_MOUSE
NC score	0.085528 (rank : 376)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	53	Target Neighborhood Hits	332	Shared Neighborhood Hits	19
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

FST_HUMAN
NC score	0.085160 (rank : 377)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	53	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

VEGFC_HUMAN
NC score	0.084586 (rank : 378)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	16
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

CTGF_MOUSE
NC score	0.084473 (rank : 379)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	53	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

KR211_HUMAN
NC score	0.083530 (rank : 380)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	53	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q3LI58	Gene names	KRTAP21-1, KAP21.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 21-1.

CELR2_MOUSE
NC score	0.082058 (rank : 381)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	53	Target Neighborhood Hits	584	Shared Neighborhood Hits	27
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

HGFA_MOUSE
NC score	0.081480 (rank : 382)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	53	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

FST_MOUSE
NC score	0.080382 (rank : 383)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	53	Target Neighborhood Hits	146	Shared Neighborhood Hits	22
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

APR3_HUMAN
NC score	0.078462 (rank : 384)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	53	Target Neighborhood Hits	50	Shared Neighborhood Hits	10
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

PGCB_HUMAN
NC score	0.078163 (rank : 385)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	53	Target Neighborhood Hits	478	Shared Neighborhood Hits	15
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

CT127_HUMAN
NC score	0.077644 (rank : 386)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

TNR14_HUMAN
NC score	0.077593 (rank : 387)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	53	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

CRDL2_HUMAN
NC score	0.077440 (rank : 388)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	53	Target Neighborhood Hits	99	Shared Neighborhood Hits	11
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

NRG4_MOUSE
NC score	0.076863 (rank : 389)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	53	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

FAT2_HUMAN
NC score	0.076764 (rank : 390)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	53	Target Neighborhood Hits	507	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

ELTD1_HUMAN
NC score	0.076627 (rank : 391)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	53	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

HGFA_HUMAN
NC score	0.075850 (rank : 392)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	53	Target Neighborhood Hits	436	Shared Neighborhood Hits	22
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

MFGM_HUMAN
NC score	0.075793 (rank : 393)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	53	Target Neighborhood Hits	150	Shared Neighborhood Hits	20
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MT1B_HUMAN
NC score	0.075629 (rank : 394)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	53	Target Neighborhood Hits	87	Shared Neighborhood Hits	12
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MUC13_MOUSE
NC score	0.074935 (rank : 395)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	53	Target Neighborhood Hits	447	Shared Neighborhood Hits	17
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

GNPTA_HUMAN
NC score	0.074909 (rank : 396)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	53	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

FA12_HUMAN
NC score	0.074722 (rank : 397)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	53	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

TNR25_HUMAN
NC score	0.074722 (rank : 398)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	53	Target Neighborhood Hits	172	Shared Neighborhood Hits	13
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

WISP1_HUMAN
NC score	0.074304 (rank : 399)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	53	Target Neighborhood Hits	121	Shared Neighborhood Hits	21
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

SMDF_HUMAN
NC score	0.074071 (rank : 400)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	53	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

PRR13_MOUSE
NC score	0.074006 (rank : 401)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	53	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQJ5, Q3U3U4	Gene names	Prr13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

GNPTA_MOUSE
NC score	0.073918 (rank : 402)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	53	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

NRG4_HUMAN
NC score	0.073370 (rank : 403)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	53	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

RSPO3_MOUSE
NC score	0.073365 (rank : 404)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	53	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO3_HUMAN
NC score	0.073320 (rank : 405)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	53	Target Neighborhood Hits	128	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

PROC_MOUSE
NC score	0.072466 (rank : 406)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	53	Target Neighborhood Hits	426	Shared Neighborhood Hits	22
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CRDL2_MOUSE
NC score	0.071752 (rank : 407)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

RSPO2_MOUSE
NC score	0.071684 (rank : 408)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	53	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

ADA15_MOUSE
NC score	0.071641 (rank : 409)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	324	Shared Neighborhood Hits	29
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

PGCA_HUMAN
NC score	0.071629 (rank : 410)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	53	Target Neighborhood Hits	821	Shared Neighborhood Hits	22
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LYAM1_HUMAN
NC score	0.071599 (rank : 411)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	53	Target Neighborhood Hits	315	Shared Neighborhood Hits	18
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

WISP1_MOUSE
NC score	0.071570 (rank : 412)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	53	Target Neighborhood Hits	123	Shared Neighborhood Hits	20
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

MUC13_HUMAN
NC score	0.071043 (rank : 413)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	53	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

ODFP_MOUSE
NC score	0.070607 (rank : 414)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	53	Target Neighborhood Hits	75	Shared Neighborhood Hits	10
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

CP003_HUMAN
NC score	0.070490 (rank : 415)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

CO8B_MOUSE
NC score	0.070160 (rank : 416)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	53	Target Neighborhood Hits	224	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

RSPO2_HUMAN
NC score	0.069956 (rank : 417)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	53	Target Neighborhood Hits	90	Shared Neighborhood Hits	8
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

WISP3_HUMAN
NC score	0.069289 (rank : 418)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	53	Target Neighborhood Hits	87	Shared Neighborhood Hits	16
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

UROL1_HUMAN
NC score	0.069134 (rank : 419)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	53	Target Neighborhood Hits	213	Shared Neighborhood Hits	14
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

IBP3_HUMAN
NC score	0.068700 (rank : 420)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

KR124_HUMAN
NC score	0.067987 (rank : 421)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	53	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

CDN2B_HUMAN
NC score	0.067242 (rank : 422)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	53	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

PAPPA_HUMAN
NC score	0.066803 (rank : 423)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	53	Target Neighborhood Hits	161	Shared Neighborhood Hits	16
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

ADAM8_HUMAN
NC score	0.066331 (rank : 424)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	53	Target Neighborhood Hits	327	Shared Neighborhood Hits	26
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

CO7_HUMAN
NC score	0.066288 (rank : 425)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	53	Target Neighborhood Hits	278	Shared Neighborhood Hits	13
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

SHAN1_HUMAN
NC score	0.066110 (rank : 426)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	53	Target Neighborhood Hits	1041	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

FA9_HUMAN
NC score	0.065974 (rank : 427)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	53	Target Neighborhood Hits	421	Shared Neighborhood Hits	23
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

ADAM8_MOUSE
NC score	0.065771 (rank : 428)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	53	Target Neighborhood Hits	326	Shared Neighborhood Hits	25
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

PRG4_MOUSE
NC score	0.065293 (rank : 429)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	53	Target Neighborhood Hits	624	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

UROL1_MOUSE
NC score	0.064484 (rank : 430)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	53	Target Neighborhood Hits	235	Shared Neighborhood Hits	13
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

FA10_MOUSE
NC score	0.064242 (rank : 431)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	53	Target Neighborhood Hits	435	Shared Neighborhood Hits	23
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

KRA63_HUMAN
NC score	0.064224 (rank : 432)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	53	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q3LI67	Gene names	KRTAP6-3, KAP6.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-3.

CD2A1_MOUSE
NC score	0.064033 (rank : 433)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	53	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

FA10_HUMAN
NC score	0.063849 (rank : 434)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	53	Target Neighborhood Hits	431	Shared Neighborhood Hits	23
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

MT2_MOUSE
NC score	0.063809 (rank : 435)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

NICE1_HUMAN
NC score	0.063801 (rank : 436)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	53	Target Neighborhood Hits	12	Shared Neighborhood Hits	1
SwissProt Accessions	Q9UGL9	Gene names	NICE1, C1orf42
Domain Architecture	No domain graphic available
Description	Protein NICE-1.

NRG2_MOUSE
NC score	0.063407 (rank : 437)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	53	Target Neighborhood Hits	392	Shared Neighborhood Hits	12
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG2_HUMAN
NC score	0.063254 (rank : 438)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	53	Target Neighborhood Hits	419	Shared Neighborhood Hits	14
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

IBP1_HUMAN
NC score	0.063174 (rank : 439)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

MT1_MOUSE
NC score	0.063157 (rank : 440)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	53	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

NEU1_MOUSE
NC score	0.063024 (rank : 441)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	53	Target Neighborhood Hits	64	Shared Neighborhood Hits	13
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

PRR13_HUMAN
NC score	0.062732 (rank : 442)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	53	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZ81, Q6FIG7, Q6MZP8, Q6NXQ6, Q6PKF9	Gene names	PRR13
Domain Architecture	No domain graphic available
Description	Proline-rich protein 13.

FA7_HUMAN
NC score	0.062620 (rank : 443)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	53	Target Neighborhood Hits	404	Shared Neighborhood Hits	20
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

LCE3D_HUMAN
NC score	0.062326 (rank : 444)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	53	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE3	Gene names	LCE3D, LEP16, SPRL6A, SPRL6B
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3D (Late envelope protein 16) (Small proline-rich-like epidermal differentiation complex protein 6A) (Small proline-rich-like epidermal differentiation complex protein 6B).

ASB16_MOUSE
NC score	0.061948 (rank : 445)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	53	Target Neighborhood Hits	306	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

PAPPA_MOUSE
NC score	0.061678 (rank : 446)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	53	Target Neighborhood Hits	153	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

TNR9_HUMAN
NC score	0.061269 (rank : 447)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	53	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

NRG1_HUMAN
NC score	0.061089 (rank : 448)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	53	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

EZH1_HUMAN
NC score	0.060890 (rank : 449)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	53	Target Neighborhood Hits	121	Shared Neighborhood Hits	18
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

CO6_HUMAN
NC score	0.060752 (rank : 450)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	53	Target Neighborhood Hits	331	Shared Neighborhood Hits	17
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

EZH1_MOUSE
NC score	0.060731 (rank : 451)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	126	Shared Neighborhood Hits	18
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

ANR15_HUMAN
NC score	0.060730 (rank : 452)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	53	Target Neighborhood Hits	478	Shared Neighborhood Hits	5
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

PRP2_MOUSE
NC score	0.060286 (rank : 453)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	53	Target Neighborhood Hits	347	Shared Neighborhood Hits	6
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

KRA61_HUMAN
NC score	0.060098 (rank : 454)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	53	Target Neighborhood Hits	5	Shared Neighborhood Hits	1
SwissProt Accessions	Q3LI64	Gene names	KRTAP6-1, KAP6.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 6-1.

CHRD_HUMAN
NC score	0.059888 (rank : 455)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

PERT_HUMAN
NC score	0.059499 (rank : 456)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	53	Target Neighborhood Hits	221	Shared Neighborhood Hits	12
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MMRN1_HUMAN
NC score	0.059380 (rank : 457)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	53	Target Neighborhood Hits	636	Shared Neighborhood Hits	13
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

ADA33_HUMAN
NC score	0.058974 (rank : 458)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	264	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

CRDL1_MOUSE
NC score	0.058614 (rank : 459)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

PROC_HUMAN
NC score	0.058523 (rank : 460)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	53	Target Neighborhood Hits	406	Shared Neighborhood Hits	19
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

ADA11_MOUSE
NC score	0.058507 (rank : 461)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	263	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CHRD_MOUSE
NC score	0.058220 (rank : 462)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

ANR38_MOUSE
NC score	0.058192 (rank : 463)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	53	Target Neighborhood Hits	512	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

PERT_MOUSE
NC score	0.057931 (rank : 464)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	53	Target Neighborhood Hits	221	Shared Neighborhood Hits	14
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

NET1_HUMAN
NC score	0.057891 (rank : 465)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	53	Target Neighborhood Hits	149	Shared Neighborhood Hits	20
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

WFDC2_HUMAN
NC score	0.057348 (rank : 466)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	53	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

TNR7_HUMAN
NC score	0.057317 (rank : 467)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	53	Target Neighborhood Hits	120	Shared Neighborhood Hits	14
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

CDN2B_MOUSE
NC score	0.057230 (rank : 468)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	53	Target Neighborhood Hits	201	Shared Neighborhood Hits	5
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

ADA11_HUMAN
NC score	0.057079 (rank : 469)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	259	Shared Neighborhood Hits	22
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

IBP2_HUMAN
NC score	0.056955 (rank : 470)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	53	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

ALK1_HUMAN
NC score	0.056521 (rank : 471)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	53	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).

IBP5_MOUSE
NC score	0.056499 (rank : 472)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_HUMAN
NC score	0.056420 (rank : 473)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	53	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

KR121_HUMAN
NC score	0.056393 (rank : 474)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	53	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

ERBB3_HUMAN
NC score	0.056200 (rank : 475)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	918	Shared Neighborhood Hits	25
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ADA15_HUMAN
NC score	0.056168 (rank : 476)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	25
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

EHMT2_HUMAN
NC score	0.056154 (rank : 477)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	53	Target Neighborhood Hits	498	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

TSG6_HUMAN
NC score	0.056125 (rank : 478)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	53	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

PGH2_MOUSE
NC score	0.055969 (rank : 479)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	53	Target Neighborhood Hits	113	Shared Neighborhood Hits	12
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

IBP3_MOUSE
NC score	0.055793 (rank : 480)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	53	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

EHMT2_MOUSE
NC score	0.055732 (rank : 481)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	53	Target Neighborhood Hits	750	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ADAM9_MOUSE
NC score	0.055722 (rank : 482)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	53	Target Neighborhood Hits	325	Shared Neighborhood Hits	23
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

EREG_HUMAN
NC score	0.055527 (rank : 483)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	53	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

NET1_MOUSE
NC score	0.055455 (rank : 484)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	53	Target Neighborhood Hits	151	Shared Neighborhood Hits	20
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

IKBE_HUMAN
NC score	0.055443 (rank : 485)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	53	Target Neighborhood Hits	288	Shared Neighborhood Hits	5
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ANR41_HUMAN
NC score	0.055280 (rank : 486)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	53	Target Neighborhood Hits	332	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

TSG6_MOUSE
NC score	0.055278 (rank : 487)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	53	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

VEGFC_MOUSE
NC score	0.055038 (rank : 488)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	53	Target Neighborhood Hits	119	Shared Neighborhood Hits	17
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

LCE3E_HUMAN
NC score	0.054852 (rank : 489)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	53	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T5B0	Gene names	LCE3E, LEP17
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3E (Late envelope protein 17).

EPGN_MOUSE
NC score	0.054532 (rank : 490)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	53	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q924X1, Q8CEX5	Gene names	Epgn
Domain Architecture	No domain graphic available
Description	Epigen precursor (Epithelial mitogen) (EPG).

EZH2_MOUSE
NC score	0.054470 (rank : 491)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	53	Target Neighborhood Hits	86	Shared Neighborhood Hits	13
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

ANR38_HUMAN
NC score	0.054435 (rank : 492)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	53	Target Neighborhood Hits	443	Shared Neighborhood Hits	5
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

BTC_MOUSE
NC score	0.054374 (rank : 493)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	12
SwissProt Accessions	Q05928	Gene names	Btc, Bcn
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

ANR23_HUMAN
NC score	0.054285 (rank : 494)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	53	Target Neighborhood Hits	291	Shared Neighborhood Hits	5
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANR49_HUMAN
NC score	0.054245 (rank : 495)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	53	Target Neighborhood Hits	282	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

ANR47_HUMAN
NC score	0.054199 (rank : 496)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	53	Target Neighborhood Hits	369	Shared Neighborhood Hits	5
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

EZH2_HUMAN
NC score	0.054141 (rank : 497)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	53	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SMR1_MOUSE
NC score	0.054104 (rank : 498)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	53	Target Neighborhood Hits	103	Shared Neighborhood Hits	4
SwissProt Accessions	Q61900	Gene names	Smr1, Msg1
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 1 precursor (Salivary protein MSG1).

MEP1A_MOUSE
NC score	0.053910 (rank : 499)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	53	Target Neighborhood Hits	166	Shared Neighborhood Hits	9
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

ASZ1_MOUSE
NC score	0.053780 (rank : 500)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	53	Target Neighborhood Hits	319	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB8_HUMAN
NC score	0.053675 (rank : 501)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	53	Target Neighborhood Hits	294	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

BCL3_HUMAN
NC score	0.053625 (rank : 502)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	53	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

PSD10_HUMAN
NC score	0.053591 (rank : 503)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	53	Target Neighborhood Hits	301	Shared Neighborhood Hits	5
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

MKS3_MOUSE
NC score	0.053392 (rank : 504)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	53	Target Neighborhood Hits	89	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

ADA33_MOUSE
NC score	0.053223 (rank : 505)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	231	Shared Neighborhood Hits	18
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ASB8_MOUSE
NC score	0.053008 (rank : 506)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	53	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

IKBA_HUMAN
NC score	0.052978 (rank : 507)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	53	Target Neighborhood Hits	280	Shared Neighborhood Hits	5
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

PGH2_HUMAN
NC score	0.052951 (rank : 508)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	53	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

ANKR6_HUMAN
NC score	0.052742 (rank : 509)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	53	Target Neighborhood Hits	439	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

MEP1A_HUMAN
NC score	0.052681 (rank : 510)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	53	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

CRDL1_HUMAN
NC score	0.052630 (rank : 511)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	53	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

PSD10_MOUSE
NC score	0.052603 (rank : 512)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	53	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

BCL3_MOUSE
NC score	0.052569 (rank : 513)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	53	Target Neighborhood Hits	388	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

PROP_MOUSE
NC score	0.052268 (rank : 514)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	53	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PA2G6_MOUSE
NC score	0.052137 (rank : 515)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	53	Target Neighborhood Hits	293	Shared Neighborhood Hits	5
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

IKBA_MOUSE
NC score	0.052025 (rank : 516)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	53	Target Neighborhood Hits	283	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ANR49_MOUSE
NC score	0.051865 (rank : 517)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	53	Target Neighborhood Hits	285	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

IBP4_HUMAN
NC score	0.051800 (rank : 518)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	53	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

WFDC5_HUMAN
NC score	0.051790 (rank : 519)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	53	Target Neighborhood Hits	65	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

ERBB3_MOUSE
NC score	0.051749 (rank : 520)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	53	Target Neighborhood Hits	898	Shared Neighborhood Hits	23
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

XLKD1_HUMAN
NC score	0.051707 (rank : 521)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	53	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5Y7, Q8TC18, Q9UNF4	Gene names	XLKD1, CRSBP1, HAR
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Hyaluronic acid receptor) (Extracellular link domain-containing protein 1).

IBP2_MOUSE
NC score	0.051689 (rank : 522)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	53	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

XLKD1_MOUSE
NC score	0.051570 (rank : 523)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	53	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHC0, Q3TUC1, Q99NE4	Gene names	Xlkd1, Crsbp1
Domain Architecture	No domain graphic available
Description	Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor (LYVE-1) (Cell surface retention sequence-binding protein 1) (CRSBP-1) (Extracellular link domain-containing protein 1).

ASZ1_HUMAN
NC score	0.051494 (rank : 524)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	53	Target Neighborhood Hits	341	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CLC14_MOUSE
NC score	0.051074 (rank : 525)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	53	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CD2A1_HUMAN
NC score	0.050625 (rank : 526)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	53	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ERBB4_HUMAN
NC score	0.050615 (rank : 527)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	53	Target Neighborhood Hits	910	Shared Neighborhood Hits	23
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ADAM9_HUMAN
NC score	0.050507 (rank : 528)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	53	Target Neighborhood Hits	243	Shared Neighborhood Hits	23
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

MT1A_HUMAN
NC score	0.050491 (rank : 529)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	53	Target Neighborhood Hits	74	Shared Neighborhood Hits	8
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

ASB16_HUMAN
NC score	0.050448 (rank : 530)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	53	Target Neighborhood Hits	286	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASTN_MOUSE
NC score	0.050160 (rank : 531)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	53	Target Neighborhood Hits	98	Shared Neighborhood Hits	10
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

IBP4_MOUSE
NC score	0.050135 (rank : 532)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	53	Target Neighborhood Hits	55	Shared Neighborhood Hits	6
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

TROAP_HUMAN
NC score	0.050086 (rank : 533)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	53	Target Neighborhood Hits	258	Shared Neighborhood Hits	6
SwissProt Accessions	Q12815	Gene names	TROAP
Domain Architecture	No domain graphic available
Description	Trophinin-associated protein (Tastin) (Trophinin-assisting protein).

EGFR_HUMAN
NC score	0.044233 (rank : 534)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	939	Shared Neighborhood Hits	22
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

KRHB6_MOUSE
NC score	0.021129 (rank : 535)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	413	Shared Neighborhood Hits	2
SwissProt Accessions	P97861, Q3TTV9	Gene names	Krthb6, Krt2-10
Domain Architecture	No domain graphic available
Description	Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6).

AMHR2_HUMAN
NC score	0.019855 (rank : 536)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	715	Shared Neighborhood Hits	9
SwissProt Accessions	Q16671, Q13762	Gene names	AMHR2, AMHR
Domain Architecture
Description	Anti-Muellerian hormone type-2 receptor precursor (EC 2.7.11.30) (Anti-Muellerian hormone type II receptor) (AMH type II receptor) (MIS type II receptor) (MISRII) (MRII).

ZN692_MOUSE
NC score	0.000242 (rank : 537)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	751	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U381	Gene names	Znf692, Zfp692
Domain Architecture	No domain graphic available
Description	Zinc finger protein 692.