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Network neighborhood for query Sequence : LCE3A_HUMAN

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LCE3A_HUMAN
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LCE3B_HUMAN
θ value	0.00665767 (rank : 1)	NC score	0.411438 (rank : 8)
Query Neighborhood Hits	29	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

TIE1_HUMAN
θ value	0.0193708 (rank : 2)	NC score	0.162558 (rank : 156)
Query Neighborhood Hits	29	Target Neighborhood Hits	1241	Shared Neighborhood Hits	20
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	0.0193708 (rank : 3)	NC score	0.162796 (rank : 155)
Query Neighborhood Hits	29	Target Neighborhood Hits	1266	Shared Neighborhood Hits	21
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

ZAN_MOUSE
θ value	0.0563607 (rank : 4)	NC score	0.330042 (rank : 15)
Query Neighborhood Hits	29	Target Neighborhood Hits	808	Shared Neighborhood Hits	27
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MEGF6_HUMAN
θ value	0.125558 (rank : 5)	NC score	0.291484 (rank : 22)
Query Neighborhood Hits	29	Target Neighborhood Hits	671	Shared Neighborhood Hits	26
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

ZAN_HUMAN
θ value	0.163984 (rank : 6)	NC score	0.273504 (rank : 26)
Query Neighborhood Hits	29	Target Neighborhood Hits	679	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

LCE3C_HUMAN
θ value	0.365318 (rank : 7)	NC score	0.592667 (rank : 2)
Query Neighborhood Hits	29	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

GRN_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.381055 (rank : 11)
Query Neighborhood Hits	29	Target Neighborhood Hits	268	Shared Neighborhood Hits	22
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

NOTC4_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.204337 (rank : 57)
Query Neighborhood Hits	29	Target Neighborhood Hits	905	Shared Neighborhood Hits	26
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

STAB1_HUMAN
θ value	0.47712 (rank : 10)	NC score	0.251824 (rank : 36)
Query Neighborhood Hits	29	Target Neighborhood Hits	546	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

LRP8_MOUSE
θ value	0.62314 (rank : 11)	NC score	0.175879 (rank : 116)
Query Neighborhood Hits	29	Target Neighborhood Hits	385	Shared Neighborhood Hits	19
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

TIE2_MOUSE
θ value	0.813845 (rank : 12)	NC score	0.139679 (rank : 198)
Query Neighborhood Hits	29	Target Neighborhood Hits	1204	Shared Neighborhood Hits	18
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

GRN_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.350829 (rank : 12)
Query Neighborhood Hits	29	Target Neighborhood Hits	248	Shared Neighborhood Hits	21
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

SREC2_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.332156 (rank : 14)
Query Neighborhood Hits	29	Target Neighborhood Hits	645	Shared Neighborhood Hits	25
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	1.38821 (rank : 15)	NC score	0.328289 (rank : 16)
Query Neighborhood Hits	29	Target Neighborhood Hits	605	Shared Neighborhood Hits	24
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.326355 (rank : 17)
Query Neighborhood Hits	29	Target Neighborhood Hits	645	Shared Neighborhood Hits	26
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ADA32_MOUSE
θ value	2.36792 (rank : 17)	NC score	0.057786 (rank : 386)
Query Neighborhood Hits	29	Target Neighborhood Hits	219	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

LAMB2_HUMAN
θ value	2.36792 (rank : 18)	NC score	0.197855 (rank : 67)
Query Neighborhood Hits	29	Target Neighborhood Hits	692	Shared Neighborhood Hits	21
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LRP8_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.180058 (rank : 103)
Query Neighborhood Hits	29	Target Neighborhood Hits	346	Shared Neighborhood Hits	22
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

JAG2_HUMAN
θ value	3.0926 (rank : 20)	NC score	0.223105 (rank : 43)
Query Neighborhood Hits	29	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

FRAS1_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.175467 (rank : 117)
Query Neighborhood Hits	29	Target Neighborhood Hits	759	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

STAB1_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.252614 (rank : 35)
Query Neighborhood Hits	29	Target Neighborhood Hits	566	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

LTBP4_MOUSE
θ value	5.27518 (rank : 23)	NC score	0.190528 (rank : 86)
Query Neighborhood Hits	29	Target Neighborhood Hits	607	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

K1H5_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.009603 (rank : 452)
Query Neighborhood Hits	29	Target Neighborhood Hits	362	Shared Neighborhood Hits	1
SwissProt Accessions	Q92764, O76012, Q92651	Gene names	KRTHA5, HHA5, HKA5
Domain Architecture
Description	Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5).

LRP2_HUMAN
θ value	6.88961 (rank : 25)	NC score	0.174165 (rank : 120)
Query Neighborhood Hits	29	Target Neighborhood Hits	573	Shared Neighborhood Hits	26
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ADA30_HUMAN
θ value	8.99809 (rank : 26)	NC score	0.051846 (rank : 431)
Query Neighborhood Hits	29	Target Neighborhood Hits	391	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

JAG2_MOUSE
θ value	8.99809 (rank : 27)	NC score	0.221042 (rank : 47)
Query Neighborhood Hits	29	Target Neighborhood Hits	504	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

LAMA2_HUMAN
θ value	8.99809 (rank : 28)	NC score	0.165141 (rank : 142)
Query Neighborhood Hits	29	Target Neighborhood Hits	1092	Shared Neighborhood Hits	22
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

UBP36_HUMAN
θ value	8.99809 (rank : 29)	NC score	0.020855 (rank : 451)
Query Neighborhood Hits	29	Target Neighborhood Hits	232	Shared Neighborhood Hits	1
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

ADA10_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.055295 (rank : 406)
Query Neighborhood Hits	29	Target Neighborhood Hits	189	Shared Neighborhood Hits	13
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 31)	NC score	0.050591 (rank : 441)
Query Neighborhood Hits	29	Target Neighborhood Hits	194	Shared Neighborhood Hits	13
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA11_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.063932 (rank : 363)
Query Neighborhood Hits	29	Target Neighborhood Hits	259	Shared Neighborhood Hits	18
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.064743 (rank : 361)
Query Neighborhood Hits	29	Target Neighborhood Hits	263	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA15_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.062632 (rank : 368)
Query Neighborhood Hits	29	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

ADA15_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.076806 (rank : 331)
Query Neighborhood Hits	29	Target Neighborhood Hits	324	Shared Neighborhood Hits	24
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.050010 (rank : 450)
Query Neighborhood Hits	29	Target Neighborhood Hits	223	Shared Neighborhood Hits	14
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA18_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.056485 (rank : 396)
Query Neighborhood Hits	29	Target Neighborhood Hits	184	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

ADA18_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.065606 (rank : 358)
Query Neighborhood Hits	29	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA23_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.052465 (rank : 427)
Query Neighborhood Hits	29	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA32_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.060781 (rank : 371)
Query Neighborhood Hits	29	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA33_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.073070 (rank : 341)
Query Neighborhood Hits	29	Target Neighborhood Hits	264	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.066535 (rank : 356)
Query Neighborhood Hits	29	Target Neighborhood Hits	231	Shared Neighborhood Hits	18
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM8_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.082266 (rank : 312)
Query Neighborhood Hits	29	Target Neighborhood Hits	327	Shared Neighborhood Hits	19
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM8_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.058128 (rank : 384)
Query Neighborhood Hits	29	Target Neighborhood Hits	326	Shared Neighborhood Hits	15
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

ADAM9_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.072916 (rank : 342)
Query Neighborhood Hits	29	Target Neighborhood Hits	243	Shared Neighborhood Hits	20
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADAM9_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.070979 (rank : 345)
Query Neighborhood Hits	29	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ADM1A_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.055829 (rank : 404)
Query Neighborhood Hits	29	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.056816 (rank : 391)
Query Neighborhood Hits	29	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

AGRIN_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.195704 (rank : 69)
Query Neighborhood Hits	29	Target Neighborhood Hits	582	Shared Neighborhood Hits	26
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ALK_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.050479 (rank : 442)
Query Neighborhood Hits	29	Target Neighborhood Hits	795	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.050317 (rank : 444)
Query Neighborhood Hits	29	Target Neighborhood Hits	811	Shared Neighborhood Hits	7
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ASTN_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.055028 (rank : 411)
Query Neighborhood Hits	29	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.065252 (rank : 359)
Query Neighborhood Hits	29	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATRN_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.123095 (rank : 240)
Query Neighborhood Hits	29	Target Neighborhood Hits	525	Shared Neighborhood Hits	18
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.121383 (rank : 245)
Query Neighborhood Hits	29	Target Neighborhood Hits	519	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BMPER_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.159049 (rank : 160)
Query Neighborhood Hits	29	Target Neighborhood Hits	175	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.155552 (rank : 165)
Query Neighborhood Hits	29	Target Neighborhood Hits	194	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

C1QR1_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.149262 (rank : 181)
Query Neighborhood Hits	29	Target Neighborhood Hits	493	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.138744 (rank : 199)
Query Neighborhood Hits	29	Target Neighborhood Hits	342	Shared Neighborhood Hits	22
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD248_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.142901 (rank : 192)
Query Neighborhood Hits	29	Target Neighborhood Hits	679	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.133142 (rank : 214)
Query Neighborhood Hits	29	Target Neighborhood Hits	578	Shared Neighborhood Hits	19
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD320_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.081115 (rank : 314)
Query Neighborhood Hits	29	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD97_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.096637 (rank : 289)
Query Neighborhood Hits	29	Target Neighborhood Hits	353	Shared Neighborhood Hits	19
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.080272 (rank : 320)
Query Neighborhood Hits	29	Target Neighborhood Hits	295	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CELR1_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.077205 (rank : 329)
Query Neighborhood Hits	29	Target Neighborhood Hits	613	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.074750 (rank : 337)
Query Neighborhood Hits	29	Target Neighborhood Hits	617	Shared Neighborhood Hits	20
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.075971 (rank : 333)
Query Neighborhood Hits	29	Target Neighborhood Hits	657	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR2_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.070193 (rank : 349)
Query Neighborhood Hits	29	Target Neighborhood Hits	584	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR3_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.080278 (rank : 319)
Query Neighborhood Hits	29	Target Neighborhood Hits	680	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.082589 (rank : 311)
Query Neighborhood Hits	29	Target Neighborhood Hits	687	Shared Neighborhood Hits	23
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CFC1_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.137293 (rank : 201)
Query Neighborhood Hits	29	Target Neighborhood Hits	148	Shared Neighborhood Hits	15
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.092408 (rank : 296)
Query Neighborhood Hits	29	Target Neighborhood Hits	125	Shared Neighborhood Hits	9
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CO8B_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.056325 (rank : 398)
Query Neighborhood Hits	29	Target Neighborhood Hits	224	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

COMP_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.095980 (rank : 291)
Query Neighborhood Hits	29	Target Neighborhood Hits	258	Shared Neighborhood Hits	17
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.115184 (rank : 265)
Query Neighborhood Hits	29	Target Neighborhood Hits	290	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CORIN_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.056084 (rank : 400)
Query Neighborhood Hits	29	Target Neighborhood Hits	451	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CREL1_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.173425 (rank : 123)
Query Neighborhood Hits	29	Target Neighborhood Hits	441	Shared Neighborhood Hits	20
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.164417 (rank : 149)
Query Neighborhood Hits	29	Target Neighborhood Hits	524	Shared Neighborhood Hits	20
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.164794 (rank : 148)
Query Neighborhood Hits	29	Target Neighborhood Hits	362	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM1_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.178517 (rank : 108)
Query Neighborhood Hits	29	Target Neighborhood Hits	457	Shared Neighborhood Hits	22
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.182833 (rank : 99)
Query Neighborhood Hits	29	Target Neighborhood Hits	444	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.193867 (rank : 73)
Query Neighborhood Hits	29	Target Neighborhood Hits	453	Shared Neighborhood Hits	24
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CSF1R_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.055108 (rank : 409)
Query Neighborhood Hits	29	Target Neighborhood Hits	943	Shared Neighborhood Hits	3
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSF1R_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.054265 (rank : 415)
Query Neighborhood Hits	29	Target Neighborhood Hits	983	Shared Neighborhood Hits	3
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSPG2_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.103819 (rank : 278)
Query Neighborhood Hits	29	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.106903 (rank : 275)
Query Neighborhood Hits	29	Target Neighborhood Hits	711	Shared Neighborhood Hits	19
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.095506 (rank : 293)
Query Neighborhood Hits	29	Target Neighborhood Hits	676	Shared Neighborhood Hits	18
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.095267 (rank : 295)
Query Neighborhood Hits	29	Target Neighborhood Hits	657	Shared Neighborhood Hits	18
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CT127_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.059604 (rank : 377)
Query Neighborhood Hits	29	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CUBN_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.149554 (rank : 180)
Query Neighborhood Hits	29	Target Neighborhood Hits	482	Shared Neighborhood Hits	24
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.152742 (rank : 173)
Query Neighborhood Hits	29	Target Neighborhood Hits	477	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CYR61_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.056928 (rank : 390)
Query Neighborhood Hits	29	Target Neighborhood Hits	159	Shared Neighborhood Hits	10
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.056371 (rank : 397)
Query Neighborhood Hits	29	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

DLK_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.209962 (rank : 54)
Query Neighborhood Hits	29	Target Neighborhood Hits	401	Shared Neighborhood Hits	25
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.215672 (rank : 48)
Query Neighborhood Hits	29	Target Neighborhood Hits	374	Shared Neighborhood Hits	25
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.201043 (rank : 62)
Query Neighborhood Hits	29	Target Neighborhood Hits	455	Shared Neighborhood Hits	25
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.202645 (rank : 58)
Query Neighborhood Hits	29	Target Neighborhood Hits	456	Shared Neighborhood Hits	25
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.192412 (rank : 79)
Query Neighborhood Hits	29	Target Neighborhood Hits	419	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.200857 (rank : 63)
Query Neighborhood Hits	29	Target Neighborhood Hits	399	Shared Neighborhood Hits	23
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.213271 (rank : 51)
Query Neighborhood Hits	29	Target Neighborhood Hits	435	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.212182 (rank : 52)
Query Neighborhood Hits	29	Target Neighborhood Hits	440	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.192800 (rank : 78)
Query Neighborhood Hits	29	Target Neighborhood Hits	460	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.187380 (rank : 88)
Query Neighborhood Hits	29	Target Neighborhood Hits	413	Shared Neighborhood Hits	23
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.130697 (rank : 217)
Query Neighborhood Hits	29	Target Neighborhood Hits	292	Shared Neighborhood Hits	21
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.137100 (rank : 202)
Query Neighborhood Hits	29	Target Neighborhood Hits	317	Shared Neighborhood Hits	20
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.164799 (rank : 147)
Query Neighborhood Hits	29	Target Neighborhood Hits	325	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.171179 (rank : 128)
Query Neighborhood Hits	29	Target Neighborhood Hits	287	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.134878 (rank : 211)
Query Neighborhood Hits	29	Target Neighborhood Hits	270	Shared Neighborhood Hits	17
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.130357 (rank : 218)
Query Neighborhood Hits	29	Target Neighborhood Hits	266	Shared Neighborhood Hits	17
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.202227 (rank : 59)
Query Neighborhood Hits	29	Target Neighborhood Hits	365	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.199078 (rank : 64)
Query Neighborhood Hits	29	Target Neighborhood Hits	379	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGFR_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.054371 (rank : 414)
Query Neighborhood Hits	29	Target Neighborhood Hits	939	Shared Neighborhood Hits	14
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.053909 (rank : 420)
Query Neighborhood Hits	29	Target Neighborhood Hits	927	Shared Neighborhood Hits	14
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EGF_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.141024 (rank : 196)
Query Neighborhood Hits	29	Target Neighborhood Hits	343	Shared Neighborhood Hits	22
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.163682 (rank : 152)
Query Neighborhood Hits	29	Target Neighborhood Hits	358	Shared Neighborhood Hits	24
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ELTD1_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.089773 (rank : 299)
Query Neighborhood Hits	29	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.113942 (rank : 267)
Query Neighborhood Hits	29	Target Neighborhood Hits	382	Shared Neighborhood Hits	21
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.108244 (rank : 273)
Query Neighborhood Hits	29	Target Neighborhood Hits	349	Shared Neighborhood Hits	20
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.097776 (rank : 286)
Query Neighborhood Hits	29	Target Neighborhood Hits	345	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EPHA1_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.051629 (rank : 433)
Query Neighborhood Hits	29	Target Neighborhood Hits	997	Shared Neighborhood Hits	14
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHAA_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.053332 (rank : 421)
Query Neighborhood Hits	29	Target Neighborhood Hits	960	Shared Neighborhood Hits	13
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHB4_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.058074 (rank : 385)
Query Neighborhood Hits	29	Target Neighborhood Hits	1056	Shared Neighborhood Hits	14
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB4_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.052723 (rank : 424)
Query Neighborhood Hits	29	Target Neighborhood Hits	1013	Shared Neighborhood Hits	15
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHB6_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.050605 (rank : 440)
Query Neighborhood Hits	29	Target Neighborhood Hits	912	Shared Neighborhood Hits	12
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

ERBB2_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.052123 (rank : 428)
Query Neighborhood Hits	29	Target Neighborhood Hits	1073	Shared Neighborhood Hits	10
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.054086 (rank : 419)
Query Neighborhood Hits	29	Target Neighborhood Hits	918	Shared Neighborhood Hits	11
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.060653 (rank : 372)
Query Neighborhood Hits	29	Target Neighborhood Hits	918	Shared Neighborhood Hits	13
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.059591 (rank : 378)
Query Neighborhood Hits	29	Target Neighborhood Hits	898	Shared Neighborhood Hits	12
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.059734 (rank : 376)
Query Neighborhood Hits	29	Target Neighborhood Hits	910	Shared Neighborhood Hits	14
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ESM1_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.208655 (rank : 55)
Query Neighborhood Hits	29	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.165073 (rank : 144)
Query Neighborhood Hits	29	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA12_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.056155 (rank : 399)
Query Neighborhood Hits	29	Target Neighborhood Hits	425	Shared Neighborhood Hits	20
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA9_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.056572 (rank : 395)
Query Neighborhood Hits	29	Target Neighborhood Hits	421	Shared Neighborhood Hits	19
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FAT2_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.058147 (rank : 383)
Query Neighborhood Hits	29	Target Neighborhood Hits	507	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FATH_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.074951 (rank : 336)
Query Neighborhood Hits	29	Target Neighborhood Hits	570	Shared Neighborhood Hits	20
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FBLN1_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.153996 (rank : 169)
Query Neighborhood Hits	29	Target Neighborhood Hits	324	Shared Neighborhood Hits	21
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.166243 (rank : 137)
Query Neighborhood Hits	29	Target Neighborhood Hits	329	Shared Neighborhood Hits	25
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.155140 (rank : 166)
Query Neighborhood Hits	29	Target Neighborhood Hits	392	Shared Neighborhood Hits	21
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.152682 (rank : 174)
Query Neighborhood Hits	29	Target Neighborhood Hits	505	Shared Neighborhood Hits	23
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.123086 (rank : 241)
Query Neighborhood Hits	29	Target Neighborhood Hits	293	Shared Neighborhood Hits	20
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.116168 (rank : 262)
Query Neighborhood Hits	29	Target Neighborhood Hits	279	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.135071 (rank : 210)
Query Neighborhood Hits	29	Target Neighborhood Hits	278	Shared Neighborhood Hits	21
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.129887 (rank : 219)
Query Neighborhood Hits	29	Target Neighborhood Hits	270	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.127381 (rank : 224)
Query Neighborhood Hits	29	Target Neighborhood Hits	329	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.126769 (rank : 226)
Query Neighborhood Hits	29	Target Neighborhood Hits	317	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.179276 (rank : 104)
Query Neighborhood Hits	29	Target Neighborhood Hits	557	Shared Neighborhood Hits	25
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.178492 (rank : 109)
Query Neighborhood Hits	29	Target Neighborhood Hits	563	Shared Neighborhood Hits	25
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.179217 (rank : 105)
Query Neighborhood Hits	29	Target Neighborhood Hits	560	Shared Neighborhood Hits	25
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.177875 (rank : 111)
Query Neighborhood Hits	29	Target Neighborhood Hits	549	Shared Neighborhood Hits	25
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.186917 (rank : 91)
Query Neighborhood Hits	29	Target Neighborhood Hits	543	Shared Neighborhood Hits	26
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FLT3_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.055877 (rank : 403)
Query Neighborhood Hits	29	Target Neighborhood Hits	843	Shared Neighborhood Hits	3
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

FLT3_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.056798 (rank : 392)
Query Neighborhood Hits	29	Target Neighborhood Hits	847	Shared Neighborhood Hits	3
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

FRAS1_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.175395 (rank : 118)
Query Neighborhood Hits	29	Target Neighborhood Hits	747	Shared Neighborhood Hits	22
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FSTL3_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.057640 (rank : 388)
Query Neighborhood Hits	29	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.066985 (rank : 355)
Query Neighborhood Hits	29	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

GAS6_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.149191 (rank : 182)
Query Neighborhood Hits	29	Target Neighborhood Hits	348	Shared Neighborhood Hits	22
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.134463 (rank : 212)
Query Neighborhood Hits	29	Target Neighborhood Hits	343	Shared Neighborhood Hits	23
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

HABP2_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.077146 (rank : 330)
Query Neighborhood Hits	29	Target Neighborhood Hits	431	Shared Neighborhood Hits	19
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.073904 (rank : 340)
Query Neighborhood Hits	29	Target Neighborhood Hits	445	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HGFA_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.057764 (rank : 387)
Query Neighborhood Hits	29	Target Neighborhood Hits	436	Shared Neighborhood Hits	19
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.059891 (rank : 375)
Query Neighborhood Hits	29	Target Neighborhood Hits	419	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HHIP_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.160139 (rank : 158)
Query Neighborhood Hits	29	Target Neighborhood Hits	249	Shared Neighborhood Hits	18
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.153390 (rank : 170)
Query Neighborhood Hits	29	Target Neighborhood Hits	219	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HMCN1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.098261 (rank : 285)
Query Neighborhood Hits	29	Target Neighborhood Hits	983	Shared Neighborhood Hits	25
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

IGF1R_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.055414 (rank : 405)
Query Neighborhood Hits	29	Target Neighborhood Hits	977	Shared Neighborhood Hits	12
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.056688 (rank : 393)
Query Neighborhood Hits	29	Target Neighborhood Hits	973	Shared Neighborhood Hits	13
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSRR_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.063005 (rank : 367)
Query Neighborhood Hits	29	Target Neighborhood Hits	950	Shared Neighborhood Hits	15
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSRR_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.063754 (rank : 365)
Query Neighborhood Hits	29	Target Neighborhood Hits	961	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

INSR_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.055933 (rank : 401)
Query Neighborhood Hits	29	Target Neighborhood Hits	963	Shared Neighborhood Hits	13
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.053042 (rank : 422)
Query Neighborhood Hits	29	Target Neighborhood Hits	968	Shared Neighborhood Hits	12
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

ITB1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.080702 (rank : 317)
Query Neighborhood Hits	29	Target Neighborhood Hits	298	Shared Neighborhood Hits	18
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.083935 (rank : 307)
Query Neighborhood Hits	29	Target Neighborhood Hits	283	Shared Neighborhood Hits	18
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.124076 (rank : 236)
Query Neighborhood Hits	29	Target Neighborhood Hits	282	Shared Neighborhood Hits	20
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.125281 (rank : 233)
Query Neighborhood Hits	29	Target Neighborhood Hits	326	Shared Neighborhood Hits	23
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.127357 (rank : 225)
Query Neighborhood Hits	29	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.126199 (rank : 228)
Query Neighborhood Hits	29	Target Neighborhood Hits	319	Shared Neighborhood Hits	20
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB4_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.133479 (rank : 213)
Query Neighborhood Hits	29	Target Neighborhood Hits	458	Shared Neighborhood Hits	20
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.121746 (rank : 243)
Query Neighborhood Hits	29	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.124597 (rank : 235)
Query Neighborhood Hits	29	Target Neighborhood Hits	329	Shared Neighborhood Hits	19
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.135517 (rank : 209)
Query Neighborhood Hits	29	Target Neighborhood Hits	318	Shared Neighborhood Hits	21
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.136877 (rank : 203)
Query Neighborhood Hits	29	Target Neighborhood Hits	341	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.124029 (rank : 237)
Query Neighborhood Hits	29	Target Neighborhood Hits	290	Shared Neighborhood Hits	22
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.117695 (rank : 258)
Query Neighborhood Hits	29	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.114011 (rank : 266)
Query Neighborhood Hits	29	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

JAG1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.214264 (rank : 49)
Query Neighborhood Hits	29	Target Neighborhood Hits	514	Shared Neighborhood Hits	24
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.213964 (rank : 50)
Query Neighborhood Hits	29	Target Neighborhood Hits	518	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

KIT_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.050281 (rank : 446)
Query Neighborhood Hits	29	Target Neighborhood Hits	953	Shared Neighborhood Hits	3
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.051940 (rank : 430)
Query Neighborhood Hits	29	Target Neighborhood Hits	949	Shared Neighborhood Hits	3
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KR101_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.222115 (rank : 45)
Query Neighborhood Hits	29	Target Neighborhood Hits	261	Shared Neighborhood Hits	21
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.197953 (rank : 66)
Query Neighborhood Hits	29	Target Neighborhood Hits	264	Shared Neighborhood Hits	19
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.128971 (rank : 222)
Query Neighborhood Hits	29	Target Neighborhood Hits	212	Shared Neighborhood Hits	17
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR104_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.236649 (rank : 41)
Query Neighborhood Hits	29	Target Neighborhood Hits	313	Shared Neighborhood Hits	22
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.201095 (rank : 60)
Query Neighborhood Hits	29	Target Neighborhood Hits	271	Shared Neighborhood Hits	19
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.211614 (rank : 53)
Query Neighborhood Hits	29	Target Neighborhood Hits	347	Shared Neighborhood Hits	22
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.231329 (rank : 42)
Query Neighborhood Hits	29	Target Neighborhood Hits	330	Shared Neighborhood Hits	23
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.181212 (rank : 102)
Query Neighborhood Hits	29	Target Neighborhood Hits	226	Shared Neighborhood Hits	19
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.198333 (rank : 65)
Query Neighborhood Hits	29	Target Neighborhood Hits	226	Shared Neighborhood Hits	19
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.110876 (rank : 271)
Query Neighborhood Hits	29	Target Neighborhood Hits	232	Shared Neighborhood Hits	15
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.193439 (rank : 74)
Query Neighborhood Hits	29	Target Neighborhood Hits	269	Shared Neighborhood Hits	20
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.163334 (rank : 153)
Query Neighborhood Hits	29	Target Neighborhood Hits	219	Shared Neighborhood Hits	19
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR122_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.059292 (rank : 379)
Query Neighborhood Hits	29	Target Neighborhood Hits	97	Shared Neighborhood Hits	8
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

KR171_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.285080 (rank : 23)
Query Neighborhood Hits	29	Target Neighborhood Hits	144	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR211_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.074156 (rank : 339)
Query Neighborhood Hits	29	Target Neighborhood Hits	10	Shared Neighborhood Hits	1
SwissProt Accessions	Q3LI58	Gene names	KRTAP21-1, KAP21.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 21-1.

KR221_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.054115 (rank : 418)
Query Neighborhood Hits	29	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

KR410_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.120721 (rank : 247)
Query Neighborhood Hits	29	Target Neighborhood Hits	156	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.132991 (rank : 216)
Query Neighborhood Hits	29	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.126017 (rank : 229)
Query Neighborhood Hits	29	Target Neighborhood Hits	199	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.245373 (rank : 40)
Query Neighborhood Hits	29	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.297215 (rank : 19)
Query Neighborhood Hits	29	Target Neighborhood Hits	231	Shared Neighborhood Hits	21
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.176407 (rank : 115)
Query Neighborhood Hits	29	Target Neighborhood Hits	155	Shared Neighborhood Hits	14
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.193200 (rank : 75)
Query Neighborhood Hits	29	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.166522 (rank : 136)
Query Neighborhood Hits	29	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.070352 (rank : 347)
Query Neighborhood Hits	29	Target Neighborhood Hits	192	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA42_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.064536 (rank : 362)
Query Neighborhood Hits	29	Target Neighborhood Hits	149	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.123931 (rank : 238)
Query Neighborhood Hits	29	Target Neighborhood Hits	162	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.164361 (rank : 151)
Query Neighborhood Hits	29	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.156171 (rank : 164)
Query Neighborhood Hits	29	Target Neighborhood Hits	204	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.302359 (rank : 18)
Query Neighborhood Hits	29	Target Neighborhood Hits	288	Shared Neighborhood Hits	24
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.256835 (rank : 33)
Query Neighborhood Hits	29	Target Neighborhood Hits	236	Shared Neighborhood Hits	22
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.284910 (rank : 24)
Query Neighborhood Hits	29	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.277265 (rank : 25)
Query Neighborhood Hits	29	Target Neighborhood Hits	270	Shared Neighborhood Hits	23
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.269467 (rank : 28)
Query Neighborhood Hits	29	Target Neighborhood Hits	257	Shared Neighborhood Hits	19
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.296911 (rank : 20)
Query Neighborhood Hits	29	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.261112 (rank : 29)
Query Neighborhood Hits	29	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.272702 (rank : 27)
Query Neighborhood Hits	29	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.258982 (rank : 32)
Query Neighborhood Hits	29	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.168355 (rank : 132)
Query Neighborhood Hits	29	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.152310 (rank : 176)
Query Neighborhood Hits	29	Target Neighborhood Hits	203	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.153032 (rank : 171)
Query Neighborhood Hits	29	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.191892 (rank : 82)
Query Neighborhood Hits	29	Target Neighborhood Hits	185	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.171547 (rank : 126)
Query Neighborhood Hits	29	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA1_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.163297 (rank : 154)
Query Neighborhood Hits	29	Target Neighborhood Hits	804	Shared Neighborhood Hits	22
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.167495 (rank : 135)
Query Neighborhood Hits	29	Target Neighborhood Hits	838	Shared Neighborhood Hits	23
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.156306 (rank : 163)
Query Neighborhood Hits	29	Target Neighborhood Hits	1198	Shared Neighborhood Hits	23
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.124810 (rank : 234)
Query Neighborhood Hits	29	Target Neighborhood Hits	760	Shared Neighborhood Hits	18
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA3_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.135573 (rank : 207)
Query Neighborhood Hits	29	Target Neighborhood Hits	859	Shared Neighborhood Hits	19
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.112331 (rank : 269)
Query Neighborhood Hits	29	Target Neighborhood Hits	708	Shared Neighborhood Hits	19
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.119313 (rank : 252)
Query Neighborhood Hits	29	Target Neighborhood Hits	584	Shared Neighborhood Hits	19
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.193128 (rank : 76)
Query Neighborhood Hits	29	Target Neighborhood Hits	976	Shared Neighborhood Hits	26
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.190557 (rank : 85)
Query Neighborhood Hits	29	Target Neighborhood Hits	828	Shared Neighborhood Hits	24
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.171208 (rank : 127)
Query Neighborhood Hits	29	Target Neighborhood Hits	1018	Shared Neighborhood Hits	21
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.175007 (rank : 119)
Query Neighborhood Hits	29	Target Neighborhood Hits	919	Shared Neighborhood Hits	20
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.197034 (rank : 68)
Query Neighborhood Hits	29	Target Neighborhood Hits	722	Shared Neighborhood Hits	22
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.165542 (rank : 141)
Query Neighborhood Hits	29	Target Neighborhood Hits	461	Shared Neighborhood Hits	21
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.177472 (rank : 113)
Query Neighborhood Hits	29	Target Neighborhood Hits	444	Shared Neighborhood Hits	21
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.136844 (rank : 204)
Query Neighborhood Hits	29	Target Neighborhood Hits	922	Shared Neighborhood Hits	18
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 247)	NC score	0.143066 (rank : 190)
Query Neighborhood Hits	29	Target Neighborhood Hits	856	Shared Neighborhood Hits	18
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.143228 (rank : 189)
Query Neighborhood Hits	29	Target Neighborhood Hits	715	Shared Neighborhood Hits	21
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.146050 (rank : 185)
Query Neighborhood Hits	29	Target Neighborhood Hits	614	Shared Neighborhood Hits	21
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.164837 (rank : 146)
Query Neighborhood Hits	29	Target Neighborhood Hits	588	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.158992 (rank : 161)
Query Neighborhood Hits	29	Target Neighborhood Hits	624	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1A_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.470349 (rank : 3)
Query Neighborhood Hits	29	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.446600 (rank : 6)
Query Neighborhood Hits	29	Target Neighborhood Hits	58	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.428690 (rank : 7)
Query Neighborhood Hits	29	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.387495 (rank : 10)
Query Neighborhood Hits	29	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.457580 (rank : 5)
Query Neighborhood Hits	29	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.466518 (rank : 4)
Query Neighborhood Hits	29	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.251784 (rank : 37)
Query Neighborhood Hits	29	Target Neighborhood Hits	50	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.140526 (rank : 197)
Query Neighborhood Hits	29	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.186935 (rank : 90)
Query Neighborhood Hits	29	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.167519 (rank : 134)
Query Neighborhood Hits	29	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	29	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3D_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.343443 (rank : 13)
Query Neighborhood Hits	29	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE3	Gene names	LCE3D, LEP16, SPRL6A, SPRL6B
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3D (Late envelope protein 16) (Small proline-rich-like epidermal differentiation complex protein 6A) (Small proline-rich-like epidermal differentiation complex protein 6B).

LCE3E_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.392256 (rank : 9)
Query Neighborhood Hits	29	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T5B0	Gene names	LCE3E, LEP17
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3E (Late envelope protein 17).

LCE4A_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.295060 (rank : 21)
Query Neighborhood Hits	29	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.183176 (rank : 98)
Query Neighborhood Hits	29	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LDLR_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.165057 (rank : 145)
Query Neighborhood Hits	29	Target Neighborhood Hits	375	Shared Neighborhood Hits	22
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.159319 (rank : 159)
Query Neighborhood Hits	29	Target Neighborhood Hits	382	Shared Neighborhood Hits	22
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LORI_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.142935 (rank : 191)
Query Neighborhood Hits	29	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRP10_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.057474 (rank : 389)
Query Neighborhood Hits	29	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.059067 (rank : 381)
Query Neighborhood Hits	29	Target Neighborhood Hits	169	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP1B_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.178143 (rank : 110)
Query Neighborhood Hits	29	Target Neighborhood Hits	602	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.178688 (rank : 106)
Query Neighborhood Hits	29	Target Neighborhood Hits	606	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.178639 (rank : 107)
Query Neighborhood Hits	29	Target Neighborhood Hits	617	Shared Neighborhood Hits	25
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP3_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.063440 (rank : 366)
Query Neighborhood Hits	29	Target Neighborhood Hits	280	Shared Neighborhood Hits	13
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP4_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.135530 (rank : 208)
Query Neighborhood Hits	29	Target Neighborhood Hits	355	Shared Neighborhood Hits	22
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.138078 (rank : 200)
Query Neighborhood Hits	29	Target Neighborhood Hits	351	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.080436 (rank : 318)
Query Neighborhood Hits	29	Target Neighborhood Hits	224	Shared Neighborhood Hits	12
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.081633 (rank : 313)
Query Neighborhood Hits	29	Target Neighborhood Hits	236	Shared Neighborhood Hits	13
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.079977 (rank : 323)
Query Neighborhood Hits	29	Target Neighborhood Hits	235	Shared Neighborhood Hits	12
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.080214 (rank : 321)
Query Neighborhood Hits	29	Target Neighborhood Hits	232	Shared Neighborhood Hits	12
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LTB1L_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.169176 (rank : 129)
Query Neighborhood Hits	29	Target Neighborhood Hits	553	Shared Neighborhood Hits	25
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.164386 (rank : 150)
Query Neighborhood Hits	29	Target Neighborhood Hits	514	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.168815 (rank : 130)
Query Neighborhood Hits	29	Target Neighborhood Hits	502	Shared Neighborhood Hits	25
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.165125 (rank : 143)
Query Neighborhood Hits	29	Target Neighborhood Hits	479	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.171941 (rank : 125)
Query Neighborhood Hits	29	Target Neighborhood Hits	552	Shared Neighborhood Hits	25
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.165966 (rank : 138)
Query Neighborhood Hits	29	Target Neighborhood Hits	617	Shared Neighborhood Hits	24
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.173958 (rank : 121)
Query Neighborhood Hits	29	Target Neighborhood Hits	502	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.167524 (rank : 133)
Query Neighborhood Hits	29	Target Neighborhood Hits	475	Shared Neighborhood Hits	26
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTK_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.050316 (rank : 445)
Query Neighborhood Hits	29	Target Neighborhood Hits	770	Shared Neighborhood Hits	6
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LYAM1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.054170 (rank : 416)
Query Neighborhood Hits	29	Target Neighborhood Hits	315	Shared Neighborhood Hits	14
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.064970 (rank : 360)
Query Neighborhood Hits	29	Target Neighborhood Hits	332	Shared Neighborhood Hits	16
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.070858 (rank : 346)
Query Neighborhood Hits	29	Target Neighborhood Hits	394	Shared Neighborhood Hits	16
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.078568 (rank : 326)
Query Neighborhood Hits	29	Target Neighborhood Hits	420	Shared Neighborhood Hits	17
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.075333 (rank : 334)
Query Neighborhood Hits	29	Target Neighborhood Hits	378	Shared Neighborhood Hits	17
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.096397 (rank : 290)
Query Neighborhood Hits	29	Target Neighborhood Hits	390	Shared Neighborhood Hits	19
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MAMC2_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.085574 (rank : 303)
Query Neighborhood Hits	29	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.087998 (rank : 300)
Query Neighborhood Hits	29	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAP4_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.067222 (rank : 354)
Query Neighborhood Hits	29	Target Neighborhood Hits	428	Shared Neighborhood Hits	4
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MATN2_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.152752 (rank : 172)
Query Neighborhood Hits	29	Target Neighborhood Hits	365	Shared Neighborhood Hits	24
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.152103 (rank : 177)
Query Neighborhood Hits	29	Target Neighborhood Hits	356	Shared Neighborhood Hits	24
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MATN3_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.115629 (rank : 264)
Query Neighborhood Hits	29	Target Neighborhood Hits	268	Shared Neighborhood Hits	19
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.102135 (rank : 279)
Query Neighborhood Hits	29	Target Neighborhood Hits	261	Shared Neighborhood Hits	17
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.126457 (rank : 227)
Query Neighborhood Hits	29	Target Neighborhood Hits	287	Shared Neighborhood Hits	23
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.100090 (rank : 281)
Query Neighborhood Hits	29	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCSP_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.100211 (rank : 280)
Query Neighborhood Hits	29	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MCSP_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.255553 (rank : 34)
Query Neighborhood Hits	29	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MDC1_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.051001 (rank : 438)
Query Neighborhood Hits	29	Target Neighborhood Hits	1446	Shared Neighborhood Hits	6
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MEGF8_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.177623 (rank : 112)
Query Neighborhood Hits	29	Target Neighborhood Hits	528	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.176520 (rank : 114)
Query Neighborhood Hits	29	Target Neighborhood Hits	520	Shared Neighborhood Hits	23
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.183437 (rank : 97)
Query Neighborhood Hits	29	Target Neighborhood Hits	557	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.182094 (rank : 100)
Query Neighborhood Hits	29	Target Neighborhood Hits	896	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MFGM_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.110408 (rank : 272)
Query Neighborhood Hits	29	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MT1A_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.052112 (rank : 429)
Query Neighborhood Hits	29	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.055269 (rank : 407)
Query Neighborhood Hits	29	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1G_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.063880 (rank : 364)
Query Neighborhood Hits	29	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT1_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.060506 (rank : 373)
Query Neighborhood Hits	29	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_MOUSE
θ value	θ > 10 (rank : 318)	NC score	0.051367 (rank : 434)
Query Neighborhood Hits	29	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.135663 (rank : 206)
Query Neighborhood Hits	29	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.078568 (rank : 325)
Query Neighborhood Hits	29	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.097050 (rank : 287)
Query Neighborhood Hits	29	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.113202 (rank : 268)
Query Neighborhood Hits	29	Target Neighborhood Hits	102	Shared Neighborhood Hits	13
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.051716 (rank : 432)
Query Neighborhood Hits	29	Target Neighborhood Hits	447	Shared Neighborhood Hits	14
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC2_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.133133 (rank : 215)
Query Neighborhood Hits	29	Target Neighborhood Hits	906	Shared Neighborhood Hits	18
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.182090 (rank : 101)
Query Neighborhood Hits	29	Target Neighborhood Hits	1020	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NAGPA_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.259168 (rank : 31)
Query Neighborhood Hits	29	Target Neighborhood Hits	282	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.260541 (rank : 30)
Query Neighborhood Hits	29	Target Neighborhood Hits	308	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.192395 (rank : 80)
Query Neighborhood Hits	29	Target Neighborhood Hits	451	Shared Neighborhood Hits	23
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.183693 (rank : 95)
Query Neighborhood Hits	29	Target Neighborhood Hits	449	Shared Neighborhood Hits	25
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.183827 (rank : 94)
Query Neighborhood Hits	29	Target Neighborhood Hits	436	Shared Neighborhood Hits	26
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NET1_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.067505 (rank : 353)
Query Neighborhood Hits	29	Target Neighborhood Hits	149	Shared Neighborhood Hits	14
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.066215 (rank : 357)
Query Neighborhood Hits	29	Target Neighborhood Hits	151	Shared Neighborhood Hits	14
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET2_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.085066 (rank : 304)
Query Neighborhood Hits	29	Target Neighborhood Hits	194	Shared Neighborhood Hits	17
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.084586 (rank : 306)
Query Neighborhood Hits	29	Target Neighborhood Hits	193	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET4_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.119212 (rank : 253)
Query Neighborhood Hits	29	Target Neighborhood Hits	191	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.118359 (rank : 256)
Query Neighborhood Hits	29	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NFX1_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.141437 (rank : 194)
Query Neighborhood Hits	29	Target Neighborhood Hits	405	Shared Neighborhood Hits	18
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.128798 (rank : 223)
Query Neighborhood Hits	29	Target Neighborhood Hits	329	Shared Neighborhood Hits	17
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.136542 (rank : 205)
Query Neighborhood Hits	29	Target Neighborhood Hits	335	Shared Neighborhood Hits	19
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.146619 (rank : 184)
Query Neighborhood Hits	29	Target Neighborhood Hits	456	Shared Neighborhood Hits	21
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.150060 (rank : 179)
Query Neighborhood Hits	29	Target Neighborhood Hits	338	Shared Neighborhood Hits	22
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.192838 (rank : 77)
Query Neighborhood Hits	29	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.194334 (rank : 70)
Query Neighborhood Hits	29	Target Neighborhood Hits	916	Shared Neighborhood Hits	25
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.185296 (rank : 92)
Query Neighborhood Hits	29	Target Neighborhood Hits	1113	Shared Neighborhood Hits	26
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.191908 (rank : 81)
Query Neighborhood Hits	29	Target Neighborhood Hits	1069	Shared Neighborhood Hits	25
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.194045 (rank : 72)
Query Neighborhood Hits	29	Target Neighborhood Hits	1062	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.194230 (rank : 71)
Query Neighborhood Hits	29	Target Neighborhood Hits	975	Shared Neighborhood Hits	25
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.204990 (rank : 56)
Query Neighborhood Hits	29	Target Neighborhood Hits	872	Shared Neighborhood Hits	26
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NTNG1_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.129784 (rank : 220)
Query Neighborhood Hits	29	Target Neighborhood Hits	247	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.123274 (rank : 239)
Query Neighborhood Hits	29	Target Neighborhood Hits	246	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.143367 (rank : 188)
Query Neighborhood Hits	29	Target Neighborhood Hits	276	Shared Neighborhood Hits	20
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.145055 (rank : 187)
Query Neighborhood Hits	29	Target Neighborhood Hits	276	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ODFP_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.056638 (rank : 394)
Query Neighborhood Hits	29	Target Neighborhood Hits	75	Shared Neighborhood Hits	10
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PAPPA_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.051013 (rank : 436)
Query Neighborhood Hits	29	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PCSK5_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.095770 (rank : 292)
Query Neighborhood Hits	29	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK5_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.183606 (rank : 96)
Query Neighborhood Hits	29	Target Neighborhood Hits	613	Shared Neighborhood Hits	23
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK6_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.099629 (rank : 283)
Query Neighborhood Hits	29	Target Neighborhood Hits	298	Shared Neighborhood Hits	19
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PGBM_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.115979 (rank : 263)
Query Neighborhood Hits	29	Target Neighborhood Hits	1113	Shared Neighborhood Hits	24
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.119082 (rank : 254)
Query Neighborhood Hits	29	Target Neighborhood Hits	1073	Shared Neighborhood Hits	23
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGCA_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.051005 (rank : 437)
Query Neighborhood Hits	29	Target Neighborhood Hits	821	Shared Neighborhood Hits	16
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCB_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.050447 (rank : 443)
Query Neighborhood Hits	29	Target Neighborhood Hits	478	Shared Neighborhood Hits	12
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.055071 (rank : 410)
Query Neighborhood Hits	29	Target Neighborhood Hits	459	Shared Neighborhood Hits	11
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PGFRB_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.050146 (rank : 448)
Query Neighborhood Hits	29	Target Neighborhood Hits	962	Shared Neighborhood Hits	3
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRB_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.050019 (rank : 449)
Query Neighborhood Hits	29	Target Neighborhood Hits	960	Shared Neighborhood Hits	3
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PROC_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.059232 (rank : 380)
Query Neighborhood Hits	29	Target Neighborhood Hits	426	Shared Neighborhood Hits	19
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROS_HUMAN
θ value	θ > 10 (rank : 366)	NC score	0.145369 (rank : 186)
Query Neighborhood Hits	29	Target Neighborhood Hits	340	Shared Neighborhood Hits	23
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 367)	NC score	0.141302 (rank : 195)
Query Neighborhood Hits	29	Target Neighborhood Hits	330	Shared Neighborhood Hits	21
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 368)	NC score	0.121533 (rank : 244)
Query Neighborhood Hits	29	Target Neighborhood Hits	422	Shared Neighborhood Hits	20
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 369)	NC score	0.129424 (rank : 221)
Query Neighborhood Hits	29	Target Neighborhood Hits	410	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PTPRU_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.055203 (rank : 408)
Query Neighborhood Hits	29	Target Neighborhood Hits	237	Shared Neighborhood Hits	5
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

RECK_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.080907 (rank : 315)
Query Neighborhood Hits	29	Target Neighborhood Hits	189	Shared Neighborhood Hits	11
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.071568 (rank : 344)
Query Neighborhood Hits	29	Target Neighborhood Hits	158	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RELN_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.076659 (rank : 332)
Query Neighborhood Hits	29	Target Neighborhood Hits	233	Shared Neighborhood Hits	15
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.080145 (rank : 322)
Query Neighborhood Hits	29	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RET_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.054152 (rank : 417)
Query Neighborhood Hits	29	Target Neighborhood Hits	873	Shared Neighborhood Hits	5
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.053033 (rank : 423)
Query Neighborhood Hits	29	Target Neighborhood Hits	884	Shared Neighborhood Hits	5
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RSPO4_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.069693 (rank : 351)
Query Neighborhood Hits	29	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.060357 (rank : 374)
Query Neighborhood Hits	29	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RYK_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.055889 (rank : 402)
Query Neighborhood Hits	29	Target Neighborhood Hits	701	Shared Neighborhood Hits	3
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.055019 (rank : 412)
Query Neighborhood Hits	29	Target Neighborhood Hits	715	Shared Neighborhood Hits	3
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SCUB3_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.172104 (rank : 124)
Query Neighborhood Hits	29	Target Neighborhood Hits	428	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.173514 (rank : 122)
Query Neighborhood Hits	29	Target Neighborhood Hits	442	Shared Neighborhood Hits	23
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SLIT1_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.121289 (rank : 246)
Query Neighborhood Hits	29	Target Neighborhood Hits	700	Shared Neighborhood Hits	22
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT1_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.117096 (rank : 261)
Query Neighborhood Hits	29	Target Neighborhood Hits	715	Shared Neighborhood Hits	21
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.120107 (rank : 249)
Query Neighborhood Hits	29	Target Neighborhood Hits	708	Shared Neighborhood Hits	23
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.117920 (rank : 257)
Query Neighborhood Hits	29	Target Neighborhood Hits	684	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.117339 (rank : 259)
Query Neighborhood Hits	29	Target Neighborhood Hits	682	Shared Neighborhood Hits	21
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SLIT3_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.120219 (rank : 248)
Query Neighborhood Hits	29	Target Neighborhood Hits	700	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SORL_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.125895 (rank : 230)
Query Neighborhood Hits	29	Target Neighborhood Hits	440	Shared Neighborhood Hits	22
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.148649 (rank : 183)
Query Neighborhood Hits	29	Target Neighborhood Hits	439	Shared Neighborhood Hits	25
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPR2B_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.070196 (rank : 348)
Query Neighborhood Hits	29	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

SPR2D_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.117218 (rank : 260)
Query Neighborhood Hits	29	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.075282 (rank : 335)
Query Neighborhood Hits	29	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2E_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.083739 (rank : 309)
Query Neighborhood Hits	29	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.119602 (rank : 251)
Query Neighborhood Hits	29	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2F_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.080767 (rank : 316)
Query Neighborhood Hits	29	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2G_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.086275 (rank : 302)
Query Neighborhood Hits	29	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.096837 (rank : 288)
Query Neighborhood Hits	29	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.099557 (rank : 284)
Query Neighborhood Hits	29	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SSPO_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.201047 (rank : 61)
Query Neighborhood Hits	29	Target Neighborhood Hits	800	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STAB2_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.246223 (rank : 39)
Query Neighborhood Hits	29	Target Neighborhood Hits	534	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.246631 (rank : 38)
Query Neighborhood Hits	29	Target Neighborhood Hits	528	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STYK1_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.054901 (rank : 413)
Query Neighborhood Hits	29	Target Neighborhood Hits	786	Shared Neighborhood Hits	3
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

STYK1_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.052659 (rank : 425)
Query Neighborhood Hits	29	Target Neighborhood Hits	779	Shared Neighborhood Hits	3
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

SUSD1_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.105241 (rank : 277)
Query Neighborhood Hits	29	Target Neighborhood Hits	285	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.091412 (rank : 298)
Query Neighborhood Hits	29	Target Neighborhood Hits	132	Shared Neighborhood Hits	13
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.111247 (rank : 270)
Query Neighborhood Hits	29	Target Neighborhood Hits	146	Shared Neighborhood Hits	14
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.095322 (rank : 294)
Query Neighborhood Hits	29	Target Neighborhood Hits	131	Shared Neighborhood Hits	13
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TECTA_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.188660 (rank : 87)
Query Neighborhood Hits	29	Target Neighborhood Hits	239	Shared Neighborhood Hits	19
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.187338 (rank : 89)
Query Neighborhood Hits	29	Target Neighborhood Hits	244	Shared Neighborhood Hits	19
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.078038 (rank : 328)
Query Neighborhood Hits	29	Target Neighborhood Hits	211	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.078458 (rank : 327)
Query Neighborhood Hits	29	Target Neighborhood Hits	214	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENA_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.190846 (rank : 83)
Query Neighborhood Hits	29	Target Neighborhood Hits	631	Shared Neighborhood Hits	25
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.184994 (rank : 93)
Query Neighborhood Hits	29	Target Neighborhood Hits	596	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.119821 (rank : 250)
Query Neighborhood Hits	29	Target Neighborhood Hits	453	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.118867 (rank : 255)
Query Neighborhood Hits	29	Target Neighborhood Hits	484	Shared Neighborhood Hits	22
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.125429 (rank : 231)
Query Neighborhood Hits	29	Target Neighborhood Hits	526	Shared Neighborhood Hits	22
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.125413 (rank : 232)
Query Neighborhood Hits	29	Target Neighborhood Hits	531	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENX_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.190594 (rank : 84)
Query Neighborhood Hits	29	Target Neighborhood Hits	789	Shared Neighborhood Hits	25
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TIE2_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.142400 (rank : 193)
Query Neighborhood Hits	29	Target Neighborhood Hits	1192	Shared Neighborhood Hits	20
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TNR14_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.070078 (rank : 350)
Query Neighborhood Hits	29	Target Neighborhood Hits	149	Shared Neighborhood Hits	13
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR25_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.087207 (rank : 301)
Query Neighborhood Hits	29	Target Neighborhood Hits	172	Shared Neighborhood Hits	10
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR7_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.052573 (rank : 426)
Query Neighborhood Hits	29	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR9_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.059034 (rank : 382)
Query Neighborhood Hits	29	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TRBM_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.165886 (rank : 140)
Query Neighborhood Hits	29	Target Neighborhood Hits	339	Shared Neighborhood Hits	24
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.152564 (rank : 175)
Query Neighborhood Hits	29	Target Neighborhood Hits	361	Shared Neighborhood Hits	23
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP1_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.083921 (rank : 308)
Query Neighborhood Hits	29	Target Neighborhood Hits	389	Shared Neighborhood Hits	18
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.084622 (rank : 305)
Query Neighborhood Hits	29	Target Neighborhood Hits	396	Shared Neighborhood Hits	18
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.067949 (rank : 352)
Query Neighborhood Hits	29	Target Neighborhood Hits	359	Shared Neighborhood Hits	17
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.072721 (rank : 343)
Query Neighborhood Hits	29	Target Neighborhood Hits	352	Shared Neighborhood Hits	17
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.099769 (rank : 282)
Query Neighborhood Hits	29	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 432)	NC score	0.107182 (rank : 274)
Query Neighborhood Hits	29	Target Neighborhood Hits	247	Shared Neighborhood Hits	21
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.092224 (rank : 297)
Query Neighborhood Hits	29	Target Neighborhood Hits	277	Shared Neighborhood Hits	17
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.106401 (rank : 276)
Query Neighborhood Hits	29	Target Neighborhood Hits	276	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROM_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.150339 (rank : 178)
Query Neighborhood Hits	29	Target Neighborhood Hits	284	Shared Neighborhood Hits	21
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.122937 (rank : 242)
Query Neighborhood Hits	29	Target Neighborhood Hits	276	Shared Neighborhood Hits	20
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.154371 (rank : 168)
Query Neighborhood Hits	29	Target Neighborhood Hits	600	Shared Neighborhood Hits	22
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.162112 (rank : 157)
Query Neighborhood Hits	29	Target Neighborhood Hits	626	Shared Neighborhood Hits	23
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VEGFC_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.074639 (rank : 338)
Query Neighborhood Hits	29	Target Neighborhood Hits	128	Shared Neighborhood Hits	13
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VGFR3_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.051063 (rank : 435)
Query Neighborhood Hits	29	Target Neighborhood Hits	1037	Shared Neighborhood Hits	3
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VGFR3_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.050921 (rank : 439)
Query Neighborhood Hits	29	Target Neighborhood Hits	1056	Shared Neighborhood Hits	3
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VLDLR_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.157390 (rank : 162)
Query Neighborhood Hits	29	Target Neighborhood Hits	383	Shared Neighborhood Hits	21
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.154836 (rank : 167)
Query Neighborhood Hits	29	Target Neighborhood Hits	360	Shared Neighborhood Hits	21
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VWF_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.165915 (rank : 139)
Query Neighborhood Hits	29	Target Neighborhood Hits	396	Shared Neighborhood Hits	23
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.168681 (rank : 131)
Query Neighborhood Hits	29	Target Neighborhood Hits	381	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WFDC3_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.061228 (rank : 369)
Query Neighborhood Hits	29	Target Neighborhood Hits	138	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WIF1_HUMAN
θ value	θ > 10 (rank : 447)	NC score	0.221704 (rank : 46)
Query Neighborhood Hits	29	Target Neighborhood Hits	392	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 448)	NC score	0.222479 (rank : 44)
Query Neighborhood Hits	29	Target Neighborhood Hits	393	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WISP2_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.050281 (rank : 447)
Query Neighborhood Hits	29	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP2_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.060859 (rank : 370)
Query Neighborhood Hits	29	Target Neighborhood Hits	129	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ZNFX1_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.079577 (rank : 324)
Query Neighborhood Hits	29	Target Neighborhood Hits	308	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	θ > 10 (rank : 452)	NC score	0.083302 (rank : 310)
Query Neighborhood Hits	29	Target Neighborhood Hits	407	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

Hits sorted by NC score

LCE3A_HUMAN
NC score	0.999962 (rank : 1)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	29	Target Neighborhood Hits	29	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3C_HUMAN
NC score	0.592667 (rank : 2)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	29	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LCE1A_HUMAN
NC score	0.470349 (rank : 3)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	29	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1F_HUMAN
NC score	0.466518 (rank : 4)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	29	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE1E_HUMAN
NC score	0.457580 (rank : 5)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	29	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1B_HUMAN
NC score	0.446600 (rank : 6)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	29	Target Neighborhood Hits	58	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
NC score	0.428690 (rank : 7)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	29	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE3B_HUMAN
NC score	0.411438 (rank : 8)	θ value	0.00665767 (rank : 1)
Query Neighborhood Hits	29	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE3E_HUMAN
NC score	0.392256 (rank : 9)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	29	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T5B0	Gene names	LCE3E, LEP17
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3E (Late envelope protein 17).

LCE1D_HUMAN
NC score	0.387495 (rank : 10)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	29	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

GRN_HUMAN
NC score	0.381055 (rank : 11)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	29	Target Neighborhood Hits	268	Shared Neighborhood Hits	22
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
NC score	0.350829 (rank : 12)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	29	Target Neighborhood Hits	248	Shared Neighborhood Hits	21
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

LCE3D_HUMAN
NC score	0.343443 (rank : 13)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	29	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE3	Gene names	LCE3D, LEP16, SPRL6A, SPRL6B
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3D (Late envelope protein 16) (Small proline-rich-like epidermal differentiation complex protein 6A) (Small proline-rich-like epidermal differentiation complex protein 6B).

SREC2_HUMAN
NC score	0.332156 (rank : 14)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	29	Target Neighborhood Hits	645	Shared Neighborhood Hits	25
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ZAN_MOUSE
NC score	0.330042 (rank : 15)	θ value	0.0563607 (rank : 4)
Query Neighborhood Hits	29	Target Neighborhood Hits	808	Shared Neighborhood Hits	27
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

SREC2_MOUSE
NC score	0.328289 (rank : 16)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	29	Target Neighborhood Hits	605	Shared Neighborhood Hits	24
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
NC score	0.326355 (rank : 17)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	29	Target Neighborhood Hits	645	Shared Neighborhood Hits	26
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

KRA51_HUMAN
NC score	0.302359 (rank : 18)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	29	Target Neighborhood Hits	288	Shared Neighborhood Hits	24
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KR511_HUMAN
NC score	0.297215 (rank : 19)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	29	Target Neighborhood Hits	231	Shared Neighborhood Hits	21
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA56_HUMAN
NC score	0.296911 (rank : 20)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	29	Target Neighborhood Hits	207	Shared Neighborhood Hits	21
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LCE4A_HUMAN
NC score	0.295060 (rank : 21)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	29	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

MEGF6_HUMAN
NC score	0.291484 (rank : 22)	θ value	0.125558 (rank : 5)
Query Neighborhood Hits	29	Target Neighborhood Hits	671	Shared Neighborhood Hits	26
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KR171_HUMAN
NC score	0.285080 (rank : 23)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	29	Target Neighborhood Hits	144	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA53_HUMAN
NC score	0.284910 (rank : 24)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	29	Target Neighborhood Hits	331	Shared Neighborhood Hits	24
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
NC score	0.277265 (rank : 25)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	29	Target Neighborhood Hits	270	Shared Neighborhood Hits	23
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

ZAN_HUMAN
NC score	0.273504 (rank : 26)	θ value	0.163984 (rank : 6)
Query Neighborhood Hits	29	Target Neighborhood Hits	679	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

KRA58_HUMAN
NC score	0.272702 (rank : 27)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	29	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA55_HUMAN
NC score	0.269467 (rank : 28)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	29	Target Neighborhood Hits	257	Shared Neighborhood Hits	19
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA57_HUMAN
NC score	0.261112 (rank : 29)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	29	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NAGPA_MOUSE
NC score	0.260541 (rank : 30)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	29	Target Neighborhood Hits	308	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_HUMAN
NC score	0.259168 (rank : 31)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	29	Target Neighborhood Hits	282	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

KRA59_HUMAN
NC score	0.258982 (rank : 32)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	29	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA52_HUMAN
NC score	0.256835 (rank : 33)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	29	Target Neighborhood Hits	236	Shared Neighborhood Hits	22
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

MCSP_MOUSE
NC score	0.255553 (rank : 34)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	29	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

STAB1_MOUSE
NC score	0.252614 (rank : 35)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	29	Target Neighborhood Hits	566	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB1_HUMAN
NC score	0.251824 (rank : 36)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	29	Target Neighborhood Hits	546	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

LCE2A_HUMAN
NC score	0.251784 (rank : 37)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	29	Target Neighborhood Hits	50	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

STAB2_MOUSE
NC score	0.246631 (rank : 38)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	29	Target Neighborhood Hits	528	Shared Neighborhood Hits	26
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STAB2_HUMAN
NC score	0.246223 (rank : 39)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	29	Target Neighborhood Hits	534	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

KR510_HUMAN
NC score	0.245373 (rank : 40)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	29	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR104_HUMAN
NC score	0.236649 (rank : 41)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	29	Target Neighborhood Hits	313	Shared Neighborhood Hits	22
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR107_HUMAN
NC score	0.231329 (rank : 42)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	29	Target Neighborhood Hits	330	Shared Neighborhood Hits	23
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

JAG2_HUMAN
NC score	0.223105 (rank : 43)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	29	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

WIF1_MOUSE
NC score	0.222479 (rank : 44)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	29	Target Neighborhood Hits	393	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

KR101_HUMAN
NC score	0.222115 (rank : 45)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	29	Target Neighborhood Hits	261	Shared Neighborhood Hits	21
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

WIF1_HUMAN
NC score	0.221704 (rank : 46)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	29	Target Neighborhood Hits	392	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

JAG2_MOUSE
NC score	0.221042 (rank : 47)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	29	Target Neighborhood Hits	504	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DLK_MOUSE
NC score	0.215672 (rank : 48)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	29	Target Neighborhood Hits	374	Shared Neighborhood Hits	25
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

JAG1_HUMAN
NC score	0.214264 (rank : 49)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	29	Target Neighborhood Hits	514	Shared Neighborhood Hits	24
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.213964 (rank : 50)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	29	Target Neighborhood Hits	518	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

DLL4_HUMAN
NC score	0.213271 (rank : 51)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	29	Target Neighborhood Hits	435	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
NC score	0.212182 (rank : 52)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	29	Target Neighborhood Hits	440	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

KR106_HUMAN
NC score	0.211614 (rank : 53)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	29	Target Neighborhood Hits	347	Shared Neighborhood Hits	22
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

DLK_HUMAN
NC score	0.209962 (rank : 54)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	29	Target Neighborhood Hits	401	Shared Neighborhood Hits	25
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

ESM1_HUMAN
NC score	0.208655 (rank : 55)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	29	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

NOTC4_MOUSE
NC score	0.204990 (rank : 56)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	29	Target Neighborhood Hits	872	Shared Neighborhood Hits	26
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_HUMAN
NC score	0.204337 (rank : 57)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	29	Target Neighborhood Hits	905	Shared Neighborhood Hits	26
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DLL1_MOUSE
NC score	0.202645 (rank : 58)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	29	Target Neighborhood Hits	456	Shared Neighborhood Hits	25
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

EGFL9_HUMAN
NC score	0.202227 (rank : 59)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	29	Target Neighborhood Hits	365	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

KR105_HUMAN
NC score	0.201095 (rank : 60)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	29	Target Neighborhood Hits	271	Shared Neighborhood Hits	19
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

SSPO_MOUSE
NC score	0.201047 (rank : 61)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	29	Target Neighborhood Hits	800	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

DLL1_HUMAN
NC score	0.201043 (rank : 62)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	29	Target Neighborhood Hits	455	Shared Neighborhood Hits	25
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL3_MOUSE
NC score	0.200857 (rank : 63)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	29	Target Neighborhood Hits	399	Shared Neighborhood Hits	23
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

EGFL9_MOUSE
NC score	0.199078 (rank : 64)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	29	Target Neighborhood Hits	379	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

KR109_HUMAN
NC score	0.198333 (rank : 65)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	29	Target Neighborhood Hits	226	Shared Neighborhood Hits	19
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR102_HUMAN
NC score	0.197953 (rank : 66)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	29	Target Neighborhood Hits	264	Shared Neighborhood Hits	19
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

LAMB2_HUMAN
NC score	0.197855 (rank : 67)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	29	Target Neighborhood Hits	692	Shared Neighborhood Hits	21
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
NC score	0.197034 (rank : 68)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	29	Target Neighborhood Hits	722	Shared Neighborhood Hits	22
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

AGRIN_HUMAN
NC score	0.195704 (rank : 69)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	29	Target Neighborhood Hits	582	Shared Neighborhood Hits	26
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NOTC1_MOUSE
NC score	0.194334 (rank : 70)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	29	Target Neighborhood Hits	916	Shared Neighborhood Hits	25
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_MOUSE
NC score	0.194230 (rank : 71)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	29	Target Neighborhood Hits	975	Shared Neighborhood Hits	25
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.194045 (rank : 72)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	29	Target Neighborhood Hits	1062	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CRUM2_HUMAN
NC score	0.193867 (rank : 73)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	29	Target Neighborhood Hits	453	Shared Neighborhood Hits	24
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

KR10B_HUMAN
NC score	0.193439 (rank : 74)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	29	Target Neighborhood Hits	269	Shared Neighborhood Hits	20
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KRA13_HUMAN
NC score	0.193200 (rank : 75)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	29	Target Neighborhood Hits	144	Shared Neighborhood Hits	13
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

LAMA5_HUMAN
NC score	0.193128 (rank : 76)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	29	Target Neighborhood Hits	976	Shared Neighborhood Hits	26
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NOTC1_HUMAN
NC score	0.192838 (rank : 77)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	29	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DNER_HUMAN
NC score	0.192800 (rank : 78)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	29	Target Neighborhood Hits	460	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DLL3_HUMAN
NC score	0.192412 (rank : 79)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	29	Target Neighborhood Hits	419	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

NELL1_HUMAN
NC score	0.192395 (rank : 80)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	29	Target Neighborhood Hits	451	Shared Neighborhood Hits	23
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NOTC2_MOUSE
NC score	0.191908 (rank : 81)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	29	Target Neighborhood Hits	1069	Shared Neighborhood Hits	25
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KRA98_HUMAN
NC score	0.191892 (rank : 82)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	29	Target Neighborhood Hits	185	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

TENA_HUMAN
NC score	0.190846 (rank : 83)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	29	Target Neighborhood Hits	631	Shared Neighborhood Hits	25
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENX_HUMAN
NC score	0.190594 (rank : 84)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	29	Target Neighborhood Hits	789	Shared Neighborhood Hits	25
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

LAMA5_MOUSE
NC score	0.190557 (rank : 85)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	29	Target Neighborhood Hits	828	Shared Neighborhood Hits	24
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LTBP4_MOUSE
NC score	0.190528 (rank : 86)	θ value	5.27518 (rank : 23)
Query Neighborhood Hits	29	Target Neighborhood Hits	607	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TECTA_HUMAN
NC score	0.188660 (rank : 87)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	29	Target Neighborhood Hits	239	Shared Neighborhood Hits	19
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

DNER_MOUSE
NC score	0.187380 (rank : 88)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	29	Target Neighborhood Hits	413	Shared Neighborhood Hits	23
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

TECTA_MOUSE
NC score	0.187338 (rank : 89)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	29	Target Neighborhood Hits	244	Shared Neighborhood Hits	19
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

LCE2C_HUMAN
NC score	0.186935 (rank : 90)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	29	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

FBN3_HUMAN
NC score	0.186917 (rank : 91)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	29	Target Neighborhood Hits	543	Shared Neighborhood Hits	26
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

NOTC2_HUMAN
NC score	0.185296 (rank : 92)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	29	Target Neighborhood Hits	1113	Shared Neighborhood Hits	26
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TENA_MOUSE
NC score	0.184994 (rank : 93)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	29	Target Neighborhood Hits	596	Shared Neighborhood Hits	24
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

NELL2_MOUSE
NC score	0.183827 (rank : 94)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	29	Target Neighborhood Hits	436	Shared Neighborhood Hits	26
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NELL2_HUMAN
NC score	0.183693 (rank : 95)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	29	Target Neighborhood Hits	449	Shared Neighborhood Hits	25
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

PCSK5_MOUSE
NC score	0.183606 (rank : 96)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	29	Target Neighborhood Hits	613	Shared Neighborhood Hits	23
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

MEGF9_HUMAN
NC score	0.183437 (rank : 97)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	29	Target Neighborhood Hits	557	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LCE5A_HUMAN
NC score	0.183176 (rank : 98)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	29	Target Neighborhood Hits	43	Shared Neighborhood Hits	7
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

CRUM1_MOUSE
NC score	0.182833 (rank : 99)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	29	Target Neighborhood Hits	444	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

MEGF9_MOUSE
NC score	0.182094 (rank : 100)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	29	Target Neighborhood Hits	896	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MUC5B_HUMAN
NC score	0.182090 (rank : 101)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	29	Target Neighborhood Hits	1020	Shared Neighborhood Hits	24
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

KR108_HUMAN
NC score	0.181212 (rank : 102)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	29	Target Neighborhood Hits	226	Shared Neighborhood Hits	19
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LRP8_HUMAN
NC score	0.180058 (rank : 103)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	29	Target Neighborhood Hits	346	Shared Neighborhood Hits	22
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

FBN1_HUMAN
NC score	0.179276 (rank : 104)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	29	Target Neighborhood Hits	557	Shared Neighborhood Hits	25
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
NC score	0.179217 (rank : 105)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	29	Target Neighborhood Hits	560	Shared Neighborhood Hits	25
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

LRP1B_MOUSE
NC score	0.178688 (rank : 106)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	29	Target Neighborhood Hits	606	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
NC score	0.178639 (rank : 107)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	29	Target Neighborhood Hits	617	Shared Neighborhood Hits	25
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

CRUM1_HUMAN
NC score	0.178517 (rank : 108)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	29	Target Neighborhood Hits	457	Shared Neighborhood Hits	22
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

FBN1_MOUSE
NC score	0.178492 (rank : 109)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	29	Target Neighborhood Hits	563	Shared Neighborhood Hits	25
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

LRP1B_HUMAN
NC score	0.178143 (rank : 110)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	29	Target Neighborhood Hits	602	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBN2_MOUSE
NC score	0.177875 (rank : 111)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	29	Target Neighborhood Hits	549	Shared Neighborhood Hits	25
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

MEGF8_HUMAN
NC score	0.177623 (rank : 112)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	29	Target Neighborhood Hits	528	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMB3_MOUSE
NC score	0.177472 (rank : 113)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	29	Target Neighborhood Hits	444	Shared Neighborhood Hits	21
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

MEGF8_MOUSE
NC score	0.176520 (rank : 114)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	29	Target Neighborhood Hits	520	Shared Neighborhood Hits	23
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KRA11_HUMAN
NC score	0.176407 (rank : 115)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	29	Target Neighborhood Hits	155	Shared Neighborhood Hits	14
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

LRP8_MOUSE
NC score	0.175879 (rank : 116)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	29	Target Neighborhood Hits	385	Shared Neighborhood Hits	19
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

FRAS1_HUMAN
NC score	0.175467 (rank : 117)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	29	Target Neighborhood Hits	759	Shared Neighborhood Hits	22
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
NC score	0.175395 (rank : 118)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	29	Target Neighborhood Hits	747	Shared Neighborhood Hits	22
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMB1_MOUSE
NC score	0.175007 (rank : 119)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	29	Target Neighborhood Hits	919	Shared Neighborhood Hits	20
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LRP2_HUMAN
NC score	0.174165 (rank : 120)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	29	Target Neighborhood Hits	573	Shared Neighborhood Hits	26
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LTBP3_HUMAN
NC score	0.173958 (rank : 121)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	29	Target Neighborhood Hits	502	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

SCUB3_MOUSE
NC score	0.173514 (rank : 122)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	29	Target Neighborhood Hits	442	Shared Neighborhood Hits	23
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

CREL1_HUMAN
NC score	0.173425 (rank : 123)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	29	Target Neighborhood Hits	441	Shared Neighborhood Hits	20
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

SCUB3_HUMAN
NC score	0.172104 (rank : 124)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	29	Target Neighborhood Hits	428	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LTBP2_HUMAN
NC score	0.171941 (rank : 125)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	29	Target Neighborhood Hits	552	Shared Neighborhood Hits	25
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KRA99_HUMAN
NC score	0.171547 (rank : 126)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	29	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMB1_HUMAN
NC score	0.171208 (rank : 127)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	29	Target Neighborhood Hits	1018	Shared Neighborhood Hits	21
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

EGFL7_MOUSE
NC score	0.171179 (rank : 128)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	29	Target Neighborhood Hits	287	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

LTB1L_HUMAN
NC score	0.169176 (rank : 129)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	29	Target Neighborhood Hits	553	Shared Neighborhood Hits	25
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.168815 (rank : 130)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	29	Target Neighborhood Hits	502	Shared Neighborhood Hits	25
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

VWF_MOUSE
NC score	0.168681 (rank : 131)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	29	Target Neighborhood Hits	381	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KRA92_HUMAN
NC score	0.168355 (rank : 132)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	29	Target Neighborhood Hits	198	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LTBP3_MOUSE
NC score	0.167524 (rank : 133)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	29	Target Neighborhood Hits	475	Shared Neighborhood Hits	26
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LCE2D_HUMAN
NC score	0.167519 (rank : 134)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	29	Target Neighborhood Hits	50	Shared Neighborhood Hits	8
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LAMA1_MOUSE
NC score	0.167495 (rank : 135)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	29	Target Neighborhood Hits	838	Shared Neighborhood Hits	23
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

KRA15_HUMAN
NC score	0.166522 (rank : 136)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	29	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

FBLN1_MOUSE
NC score	0.166243 (rank : 137)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	29	Target Neighborhood Hits	329	Shared Neighborhood Hits	25
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LTBP2_MOUSE
NC score	0.165966 (rank : 138)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	29	Target Neighborhood Hits	617	Shared Neighborhood Hits	24
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

VWF_HUMAN
NC score	0.165915 (rank : 139)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	29	Target Neighborhood Hits	396	Shared Neighborhood Hits	23
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

TRBM_HUMAN
NC score	0.165886 (rank : 140)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	29	Target Neighborhood Hits	339	Shared Neighborhood Hits	24
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LAMB3_HUMAN
NC score	0.165542 (rank : 141)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	29	Target Neighborhood Hits	461	Shared Neighborhood Hits	21
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMA2_HUMAN
NC score	0.165141 (rank : 142)	θ value	8.99809 (rank : 28)
Query Neighborhood Hits	29	Target Neighborhood Hits	1092	Shared Neighborhood Hits	22
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LTB1S_MOUSE
NC score	0.165125 (rank : 143)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	29	Target Neighborhood Hits	479	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ESM1_MOUSE
NC score	0.165073 (rank : 144)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	29	Target Neighborhood Hits	107	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

LDLR_HUMAN
NC score	0.165057 (rank : 145)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	29	Target Neighborhood Hits	375	Shared Neighborhood Hits	22
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LAMC3_HUMAN
NC score	0.164837 (rank : 146)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	29	Target Neighborhood Hits	588	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

EGFL7_HUMAN
NC score	0.164799 (rank : 147)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	29	Target Neighborhood Hits	325	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

CRIM1_HUMAN
NC score	0.164794 (rank : 148)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	29	Target Neighborhood Hits	362	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CREL1_MOUSE
NC score	0.164417 (rank : 149)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	29	Target Neighborhood Hits	524	Shared Neighborhood Hits	20
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LTB1L_MOUSE
NC score	0.164386 (rank : 150)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	29	Target Neighborhood Hits	514	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

KRA45_HUMAN
NC score	0.164361 (rank : 151)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	29	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

EGF_MOUSE
NC score	0.163682 (rank : 152)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	29	Target Neighborhood Hits	358	Shared Neighborhood Hits	24
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

KR10C_HUMAN
NC score	0.163334 (rank : 153)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	29	Target Neighborhood Hits	219	Shared Neighborhood Hits	19
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LAMA1_HUMAN
NC score	0.163297 (rank : 154)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	29	Target Neighborhood Hits	804	Shared Neighborhood Hits	22
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

TIE1_MOUSE
NC score	0.162796 (rank : 155)	θ value	0.0193708 (rank : 3)
Query Neighborhood Hits	29	Target Neighborhood Hits	1266	Shared Neighborhood Hits	21
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_HUMAN
NC score	0.162558 (rank : 156)	θ value	0.0193708 (rank : 2)
Query Neighborhood Hits	29	Target Neighborhood Hits	1241	Shared Neighborhood Hits	20
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

USH2A_MOUSE
NC score	0.162112 (rank : 157)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	29	Target Neighborhood Hits	626	Shared Neighborhood Hits	23
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

HHIP_HUMAN
NC score	0.160139 (rank : 158)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	29	Target Neighborhood Hits	249	Shared Neighborhood Hits	18
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LDLR_MOUSE
NC score	0.159319 (rank : 159)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	29	Target Neighborhood Hits	382	Shared Neighborhood Hits	22
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

BMPER_HUMAN
NC score	0.159049 (rank : 160)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	29	Target Neighborhood Hits	175	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

LAMC3_MOUSE
NC score	0.158992 (rank : 161)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	29	Target Neighborhood Hits	624	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

VLDLR_HUMAN
NC score	0.157390 (rank : 162)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	29	Target Neighborhood Hits	383	Shared Neighborhood Hits	21
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LAMA2_MOUSE
NC score	0.156306 (rank : 163)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	29	Target Neighborhood Hits	1198	Shared Neighborhood Hits	23
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KRA47_HUMAN
NC score	0.156171 (rank : 164)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	29	Target Neighborhood Hits	204	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

BMPER_MOUSE
NC score	0.155552 (rank : 165)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	29	Target Neighborhood Hits	194	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

FBLN2_HUMAN
NC score	0.155140 (rank : 166)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	29	Target Neighborhood Hits	392	Shared Neighborhood Hits	21
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

VLDLR_MOUSE
NC score	0.154836 (rank : 167)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	29	Target Neighborhood Hits	360	Shared Neighborhood Hits	21
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

USH2A_HUMAN
NC score	0.154371 (rank : 168)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	29	Target Neighborhood Hits	600	Shared Neighborhood Hits	22
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

FBLN1_HUMAN
NC score	0.153996 (rank : 169)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	29	Target Neighborhood Hits	324	Shared Neighborhood Hits	21
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

HHIP_MOUSE
NC score	0.153390 (rank : 170)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	29	Target Neighborhood Hits	219	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KRA94_HUMAN
NC score	0.153032 (rank : 171)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	29	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

MATN2_HUMAN
NC score	0.152752 (rank : 172)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	29	Target Neighborhood Hits	365	Shared Neighborhood Hits	24
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

CUBN_MOUSE
NC score	0.152742 (rank : 173)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	29	Target Neighborhood Hits	477	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

FBLN2_MOUSE
NC score	0.152682 (rank : 174)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	29	Target Neighborhood Hits	505	Shared Neighborhood Hits	23
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

TRBM_MOUSE
NC score	0.152564 (rank : 175)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	29	Target Neighborhood Hits	361	Shared Neighborhood Hits	23
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

KRA93_HUMAN
NC score	0.152310 (rank : 176)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	29	Target Neighborhood Hits	203	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

MATN2_MOUSE
NC score	0.152103 (rank : 177)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	29	Target Neighborhood Hits	356	Shared Neighborhood Hits	24
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

UROM_HUMAN
NC score	0.150339 (rank : 178)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	29	Target Neighborhood Hits	284	Shared Neighborhood Hits	21
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

NID2_MOUSE
NC score	0.150060 (rank : 179)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	29	Target Neighborhood Hits	338	Shared Neighborhood Hits	22
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

CUBN_HUMAN
NC score	0.149554 (rank : 180)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	29	Target Neighborhood Hits	482	Shared Neighborhood Hits	24
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

C1QR1_HUMAN
NC score	0.149262 (rank : 181)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	29	Target Neighborhood Hits	493	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

GAS6_HUMAN
NC score	0.149191 (rank : 182)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	29	Target Neighborhood Hits	348	Shared Neighborhood Hits	22
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

SORL_MOUSE
NC score	0.148649 (rank : 183)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	29	Target Neighborhood Hits	439	Shared Neighborhood Hits	25
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

NID2_HUMAN
NC score	0.146619 (rank : 184)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	29	Target Neighborhood Hits	456	Shared Neighborhood Hits	21
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LAMC2_MOUSE
NC score	0.146050 (rank : 185)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	29	Target Neighborhood Hits	614	Shared Neighborhood Hits	21
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

PROS_HUMAN
NC score	0.145369 (rank : 186)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	29	Target Neighborhood Hits	340	Shared Neighborhood Hits	23
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

NTNG2_MOUSE
NC score	0.145055 (rank : 187)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	29	Target Neighborhood Hits	276	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_HUMAN
NC score	0.143367 (rank : 188)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	29	Target Neighborhood Hits	276	Shared Neighborhood Hits	20
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

LAMC2_HUMAN
NC score	0.143228 (rank : 189)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	29	Target Neighborhood Hits	715	Shared Neighborhood Hits	21
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC1_MOUSE
NC score	0.143066 (rank : 190)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	29	Target Neighborhood Hits	856	Shared Neighborhood Hits	18
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LORI_MOUSE
NC score	0.142935 (rank : 191)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	29	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

CD248_HUMAN
NC score	0.142901 (rank : 192)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	29	Target Neighborhood Hits	679	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TIE2_HUMAN
NC score	0.142400 (rank : 193)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	29	Target Neighborhood Hits	1192	Shared Neighborhood Hits	20
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

NFX1_HUMAN
NC score	0.141437 (rank : 194)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	29	Target Neighborhood Hits	405	Shared Neighborhood Hits	18
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PROS_MOUSE
NC score	0.141302 (rank : 195)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	29	Target Neighborhood Hits	330	Shared Neighborhood Hits	21
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

EGF_HUMAN
NC score	0.141024 (rank : 196)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	29	Target Neighborhood Hits	343	Shared Neighborhood Hits	22
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

LCE2B_HUMAN
NC score	0.140526 (rank : 197)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	29	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

TIE2_MOUSE
NC score	0.139679 (rank : 198)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	29	Target Neighborhood Hits	1204	Shared Neighborhood Hits	18
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

C1QR1_MOUSE
NC score	0.138744 (rank : 199)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	29	Target Neighborhood Hits	342	Shared Neighborhood Hits	22
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LRP4_MOUSE
NC score	0.138078 (rank : 200)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	29	Target Neighborhood Hits	351	Shared Neighborhood Hits	21
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

CFC1_HUMAN
NC score	0.137293 (rank : 201)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	29	Target Neighborhood Hits	148	Shared Neighborhood Hits	15
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

EDIL3_MOUSE
NC score	0.137100 (rank : 202)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	29	Target Neighborhood Hits	317	Shared Neighborhood Hits	20
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

ITB6_MOUSE
NC score	0.136877 (rank : 203)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	29	Target Neighborhood Hits	341	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMC1_HUMAN
NC score	0.136844 (rank : 204)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	29	Target Neighborhood Hits	922	Shared Neighborhood Hits	18
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NID1_MOUSE
NC score	0.136542 (rank : 205)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	29	Target Neighborhood Hits	335	Shared Neighborhood Hits	19
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

MT3_HUMAN
NC score	0.135663 (rank : 206)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	29	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

LAMA3_MOUSE
NC score	0.135573 (rank : 207)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	29	Target Neighborhood Hits	859	Shared Neighborhood Hits	19
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LRP4_HUMAN
NC score	0.135530 (rank : 208)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	29	Target Neighborhood Hits	355	Shared Neighborhood Hits	22
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

ITB6_HUMAN
NC score	0.135517 (rank : 209)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	29	Target Neighborhood Hits	318	Shared Neighborhood Hits	21
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

FBLN4_HUMAN
NC score	0.135071 (rank : 210)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	29	Target Neighborhood Hits	278	Shared Neighborhood Hits	21
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

EGFL8_HUMAN
NC score	0.134878 (rank : 211)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	29	Target Neighborhood Hits	270	Shared Neighborhood Hits	17
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

GAS6_MOUSE
NC score	0.134463 (rank : 212)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	29	Target Neighborhood Hits	343	Shared Neighborhood Hits	23
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ITB4_HUMAN
NC score	0.133479 (rank : 213)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	29	Target Neighborhood Hits	458	Shared Neighborhood Hits	20
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

CD248_MOUSE
NC score	0.133142 (rank : 214)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	29	Target Neighborhood Hits	578	Shared Neighborhood Hits	19
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MUC2_HUMAN
NC score	0.133133 (rank : 215)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	29	Target Neighborhood Hits	906	Shared Neighborhood Hits	18
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

KR412_HUMAN
NC score	0.132991 (rank : 216)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	29	Target Neighborhood Hits	178	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

EDIL3_HUMAN
NC score	0.130697 (rank : 217)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	29	Target Neighborhood Hits	292	Shared Neighborhood Hits	21
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL8_MOUSE
NC score	0.130357 (rank : 218)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	29	Target Neighborhood Hits	266	Shared Neighborhood Hits	17
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

FBLN4_MOUSE
NC score	0.129887 (rank : 219)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	29	Target Neighborhood Hits	270	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

NTNG1_HUMAN
NC score	0.129784 (rank : 220)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	29	Target Neighborhood Hits	247	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PROZ_MOUSE
NC score	0.129424 (rank : 221)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	29	Target Neighborhood Hits	410	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

KR103_HUMAN
NC score	0.128971 (rank : 222)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	29	Target Neighborhood Hits	212	Shared Neighborhood Hits	17
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

NID1_HUMAN
NC score	0.128798 (rank : 223)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	29	Target Neighborhood Hits	329	Shared Neighborhood Hits	17
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

FBLN5_HUMAN
NC score	0.127381 (rank : 224)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	29	Target Neighborhood Hits	329	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

ITB3_HUMAN
NC score	0.127357 (rank : 225)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	29	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

FBLN5_MOUSE
NC score	0.126769 (rank : 226)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	29	Target Neighborhood Hits	317	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

MATN4_HUMAN
NC score	0.126457 (rank : 227)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	29	Target Neighborhood Hits	287	Shared Neighborhood Hits	23
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

ITB3_MOUSE
NC score	0.126199 (rank : 228)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	29	Target Neighborhood Hits	319	Shared Neighborhood Hits	20
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

KR414_HUMAN
NC score	0.126017 (rank : 229)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	29	Target Neighborhood Hits	199	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

SORL_HUMAN
NC score	0.125895 (rank : 230)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	29	Target Neighborhood Hits	440	Shared Neighborhood Hits	22
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TENR_HUMAN
NC score	0.125429 (rank : 231)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	29	Target Neighborhood Hits	526	Shared Neighborhood Hits	22
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
NC score	0.125413 (rank : 232)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	29	Target Neighborhood Hits	531	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

ITB2_MOUSE
NC score	0.125281 (rank : 233)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	29	Target Neighborhood Hits	326	Shared Neighborhood Hits	23
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

LAMA3_HUMAN
NC score	0.124810 (rank : 234)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	29	Target Neighborhood Hits	760	Shared Neighborhood Hits	18
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

ITB5_MOUSE
NC score	0.124597 (rank : 235)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	29	Target Neighborhood Hits	329	Shared Neighborhood Hits	19
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB2_HUMAN
NC score	0.124076 (rank : 236)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	29	Target Neighborhood Hits	282	Shared Neighborhood Hits	20
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB7_HUMAN
NC score	0.124029 (rank : 237)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	29	Target Neighborhood Hits	290	Shared Neighborhood Hits	22
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

KRA44_HUMAN
NC score	0.123931 (rank : 238)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	29	Target Neighborhood Hits	162	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

NTNG1_MOUSE
NC score	0.123274 (rank : 239)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	29	Target Neighborhood Hits	246	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

ATRN_HUMAN
NC score	0.123095 (rank : 240)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	29	Target Neighborhood Hits	525	Shared Neighborhood Hits	18
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

FBLN3_HUMAN
NC score	0.123086 (rank : 241)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	29	Target Neighborhood Hits	293	Shared Neighborhood Hits	20
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

UROM_MOUSE
NC score	0.122937 (rank : 242)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	29	Target Neighborhood Hits	276	Shared Neighborhood Hits	20
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ITB5_HUMAN
NC score	0.121746 (rank : 243)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	29	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

PROZ_HUMAN
NC score	0.121533 (rank : 244)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	29	Target Neighborhood Hits	422	Shared Neighborhood Hits	20
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

ATRN_MOUSE
NC score	0.121383 (rank : 245)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	29	Target Neighborhood Hits	519	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

SLIT1_HUMAN
NC score	0.121289 (rank : 246)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	29	Target Neighborhood Hits	700	Shared Neighborhood Hits	22
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

KR410_HUMAN
NC score	0.120721 (rank : 247)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	29	Target Neighborhood Hits	156	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

SLIT3_MOUSE
NC score	0.120219 (rank : 248)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	29	Target Neighborhood Hits	700	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SLIT2_HUMAN
NC score	0.120107 (rank : 249)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	29	Target Neighborhood Hits	708	Shared Neighborhood Hits	23
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TENN_HUMAN
NC score	0.119821 (rank : 250)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	29	Target Neighborhood Hits	453	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

SPR2F_HUMAN
NC score	0.119602 (rank : 251)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	29	Target Neighborhood Hits	33	Shared Neighborhood Hits	7
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

LAMA4_MOUSE
NC score	0.119313 (rank : 252)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	29	Target Neighborhood Hits	584	Shared Neighborhood Hits	19
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

NET4_HUMAN
NC score	0.119212 (rank : 253)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	29	Target Neighborhood Hits	191	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

PGBM_MOUSE
NC score	0.119082 (rank : 254)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	29	Target Neighborhood Hits	1073	Shared Neighborhood Hits	23
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TENN_MOUSE
NC score	0.118867 (rank : 255)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	29	Target Neighborhood Hits	484	Shared Neighborhood Hits	22
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

NET4_MOUSE
NC score	0.118359 (rank : 256)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	29	Target Neighborhood Hits	180	Shared Neighborhood Hits	17
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

SLIT2_MOUSE
NC score	0.117920 (rank : 257)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	29	Target Neighborhood Hits	684	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ITB7_MOUSE
NC score	0.117695 (rank : 258)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	29	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

SLIT3_HUMAN
NC score	0.117339 (rank : 259)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	29	Target Neighborhood Hits	682	Shared Neighborhood Hits	21
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

SPR2D_MOUSE
NC score	0.117218 (rank : 260)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	29	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SLIT1_MOUSE
NC score	0.117096 (rank : 261)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	29	Target Neighborhood Hits	715	Shared Neighborhood Hits	21
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

FBLN3_MOUSE
NC score	0.116168 (rank : 262)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	29	Target Neighborhood Hits	279	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

PGBM_HUMAN
NC score	0.115979 (rank : 263)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	29	Target Neighborhood Hits	1113	Shared Neighborhood Hits	24
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MATN3_HUMAN
NC score	0.115629 (rank : 264)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	29	Target Neighborhood Hits	268	Shared Neighborhood Hits	19
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

COMP_MOUSE
NC score	0.115184 (rank : 265)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	29	Target Neighborhood Hits	290	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

ITB8_HUMAN
NC score	0.114011 (rank : 266)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	29	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

EMR1_HUMAN
NC score	0.113942 (rank : 267)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	29	Target Neighborhood Hits	382	Shared Neighborhood Hits	21
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

MT4_MOUSE
NC score	0.113202 (rank : 268)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	29	Target Neighborhood Hits	102	Shared Neighborhood Hits	13
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

LAMA4_HUMAN
NC score	0.112331 (rank : 269)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	29	Target Neighborhood Hits	708	Shared Neighborhood Hits	19
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TDGF1_MOUSE
NC score	0.111247 (rank : 270)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	29	Target Neighborhood Hits	146	Shared Neighborhood Hits	14
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

KR10A_HUMAN
NC score	0.110876 (rank : 271)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	29	Target Neighborhood Hits	232	Shared Neighborhood Hits	15
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

MFGM_MOUSE
NC score	0.110408 (rank : 272)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	29	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

EMR1_MOUSE
NC score	0.108244 (rank : 273)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	29	Target Neighborhood Hits	349	Shared Neighborhood Hits	20
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

TSP3_MOUSE
NC score	0.107182 (rank : 274)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	29	Target Neighborhood Hits	247	Shared Neighborhood Hits	21
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

CSPG2_MOUSE
NC score	0.106903 (rank : 275)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	29	Target Neighborhood Hits	711	Shared Neighborhood Hits	19
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

TSP4_MOUSE
NC score	0.106401 (rank : 276)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	29	Target Neighborhood Hits	276	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

SUSD1_HUMAN
NC score	0.105241 (rank : 277)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	29	Target Neighborhood Hits	285	Shared Neighborhood Hits	15
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

CSPG2_HUMAN
NC score	0.103819 (rank : 278)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	29	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

MATN3_MOUSE
NC score	0.102135 (rank : 279)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	29	Target Neighborhood Hits	261	Shared Neighborhood Hits	17
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MCSP_HUMAN
NC score	0.100211 (rank : 280)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	29	Target Neighborhood Hits	48	Shared Neighborhood Hits	6
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MATN4_MOUSE
NC score	0.100090 (rank : 281)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	29	Target Neighborhood Hits	277	Shared Neighborhood Hits	20
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

TSP3_HUMAN
NC score	0.099769 (rank : 282)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	29	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

PCSK6_HUMAN
NC score	0.099629 (rank : 283)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	29	Target Neighborhood Hits	298	Shared Neighborhood Hits	19
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

SPR2I_MOUSE
NC score	0.099557 (rank : 284)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	29	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

HMCN1_HUMAN
NC score	0.098261 (rank : 285)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	29	Target Neighborhood Hits	983	Shared Neighborhood Hits	25
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

EMR2_HUMAN
NC score	0.097776 (rank : 286)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	29	Target Neighborhood Hits	345	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

MT4_HUMAN
NC score	0.097050 (rank : 287)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	29	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

SPR2H_MOUSE
NC score	0.096837 (rank : 288)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	29	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

CD97_HUMAN
NC score	0.096637 (rank : 289)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	29	Target Neighborhood Hits	353	Shared Neighborhood Hits	19
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

LYAM3_MOUSE
NC score	0.096397 (rank : 290)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	29	Target Neighborhood Hits	390	Shared Neighborhood Hits	19
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

COMP_HUMAN
NC score	0.095980 (rank : 291)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	29	Target Neighborhood Hits	258	Shared Neighborhood Hits	17
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

PCSK5_HUMAN
NC score	0.095770 (rank : 292)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	29	Target Neighborhood Hits	291	Shared Neighborhood Hits	19
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

CSPG3_HUMAN
NC score	0.095506 (rank : 293)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	29	Target Neighborhood Hits	676	Shared Neighborhood Hits	18
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TDGF2_HUMAN
NC score	0.095322 (rank : 294)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	29	Target Neighborhood Hits	131	Shared Neighborhood Hits	13
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

CSPG3_MOUSE
NC score	0.095267 (rank : 295)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	29	Target Neighborhood Hits	657	Shared Neighborhood Hits	18
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CFC1_MOUSE
NC score	0.092408 (rank : 296)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	29	Target Neighborhood Hits	125	Shared Neighborhood Hits	9
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

TSP4_HUMAN
NC score	0.092224 (rank : 297)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	29	Target Neighborhood Hits	277	Shared Neighborhood Hits	17
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TDGF1_HUMAN
NC score	0.091412 (rank : 298)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	29	Target Neighborhood Hits	132	Shared Neighborhood Hits	13
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

ELTD1_MOUSE
NC score	0.089773 (rank : 299)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	29	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

MAMC2_MOUSE
NC score	0.087998 (rank : 300)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	29	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

TNR25_HUMAN
NC score	0.087207 (rank : 301)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	29	Target Neighborhood Hits	172	Shared Neighborhood Hits	10
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

SPR2G_MOUSE
NC score	0.086275 (rank : 302)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	29	Target Neighborhood Hits	53	Shared Neighborhood Hits	6
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

MAMC2_HUMAN
NC score	0.085574 (rank : 303)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	29	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

NET2_HUMAN
NC score	0.085066 (rank : 304)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	29	Target Neighborhood Hits	194	Shared Neighborhood Hits	17
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

TSP1_MOUSE
NC score	0.084622 (rank : 305)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	29	Target Neighborhood Hits	396	Shared Neighborhood Hits	18
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

NET2_MOUSE
NC score	0.084586 (rank : 306)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	29	Target Neighborhood Hits	193	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

ITB1_MOUSE
NC score	0.083935 (rank : 307)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	29	Target Neighborhood Hits	283	Shared Neighborhood Hits	18
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

TSP1_HUMAN
NC score	0.083921 (rank : 308)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	29	Target Neighborhood Hits	389	Shared Neighborhood Hits	18
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

SPR2E_MOUSE
NC score	0.083739 (rank : 309)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	29	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

ZNFX1_MOUSE
NC score	0.083302 (rank : 310)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	29	Target Neighborhood Hits	407	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CELR3_MOUSE
NC score	0.082589 (rank : 311)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	29	Target Neighborhood Hits	687	Shared Neighborhood Hits	23
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

ADAM8_HUMAN
NC score	0.082266 (rank : 312)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	29	Target Neighborhood Hits	327	Shared Neighborhood Hits	19
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

LRP5_MOUSE
NC score	0.081633 (rank : 313)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	29	Target Neighborhood Hits	236	Shared Neighborhood Hits	13
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

CD320_HUMAN
NC score	0.081115 (rank : 314)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	29	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

RECK_HUMAN
NC score	0.080907 (rank : 315)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	29	Target Neighborhood Hits	189	Shared Neighborhood Hits	11
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

SPR2F_MOUSE
NC score	0.080767 (rank : 316)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	29	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

ITB1_HUMAN
NC score	0.080702 (rank : 317)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	29	Target Neighborhood Hits	298	Shared Neighborhood Hits	18
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

LRP5_HUMAN
NC score	0.080436 (rank : 318)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	29	Target Neighborhood Hits	224	Shared Neighborhood Hits	12
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

CELR3_HUMAN
NC score	0.080278 (rank : 319)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	29	Target Neighborhood Hits	680	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CD97_MOUSE
NC score	0.080272 (rank : 320)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	29	Target Neighborhood Hits	295	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

LRP6_MOUSE
NC score	0.080214 (rank : 321)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	29	Target Neighborhood Hits	232	Shared Neighborhood Hits	12
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

RELN_MOUSE
NC score	0.080145 (rank : 322)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	29	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

LRP6_HUMAN
NC score	0.079977 (rank : 323)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	29	Target Neighborhood Hits	235	Shared Neighborhood Hits	12
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

ZNFX1_HUMAN
NC score	0.079577 (rank : 324)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	29	Target Neighborhood Hits	308	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

MT3_MOUSE
NC score	0.078568 (rank : 325)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	29	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

LYAM2_MOUSE
NC score	0.078568 (rank : 326)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	29	Target Neighborhood Hits	420	Shared Neighborhood Hits	17
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TEFF2_MOUSE
NC score	0.078458 (rank : 327)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	29	Target Neighborhood Hits	214	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.078038 (rank : 328)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	29	Target Neighborhood Hits	211	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

CELR1_HUMAN
NC score	0.077205 (rank : 329)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	29	Target Neighborhood Hits	613	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

HABP2_HUMAN
NC score	0.077146 (rank : 330)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	29	Target Neighborhood Hits	431	Shared Neighborhood Hits	19
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

ADA15_MOUSE
NC score	0.076806 (rank : 331)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	29	Target Neighborhood Hits	324	Shared Neighborhood Hits	24
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

RELN_HUMAN
NC score	0.076659 (rank : 332)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	29	Target Neighborhood Hits	233	Shared Neighborhood Hits	15
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

CELR2_HUMAN
NC score	0.075971 (rank : 333)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	29	Target Neighborhood Hits	657	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

LYAM3_HUMAN
NC score	0.075333 (rank : 334)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	29	Target Neighborhood Hits	378	Shared Neighborhood Hits	17
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

SPR2E_HUMAN
NC score	0.075282 (rank : 335)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	29	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

FATH_HUMAN
NC score	0.074951 (rank : 336)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	29	Target Neighborhood Hits	570	Shared Neighborhood Hits	20
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

CELR1_MOUSE
NC score	0.074750 (rank : 337)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	29	Target Neighborhood Hits	617	Shared Neighborhood Hits	20
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

VEGFC_HUMAN
NC score	0.074639 (rank : 338)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	29	Target Neighborhood Hits	128	Shared Neighborhood Hits	13
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

KR211_HUMAN
NC score	0.074156 (rank : 339)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	29	Target Neighborhood Hits	10	Shared Neighborhood Hits	1
SwissProt Accessions	Q3LI58	Gene names	KRTAP21-1, KAP21.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 21-1.

HABP2_MOUSE
NC score	0.073904 (rank : 340)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	29	Target Neighborhood Hits	445	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

ADA33_HUMAN
NC score	0.073070 (rank : 341)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	29	Target Neighborhood Hits	264	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM9_HUMAN
NC score	0.072916 (rank : 342)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	29	Target Neighborhood Hits	243	Shared Neighborhood Hits	20
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

TSP2_MOUSE
NC score	0.072721 (rank : 343)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	29	Target Neighborhood Hits	352	Shared Neighborhood Hits	17
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

RECK_MOUSE
NC score	0.071568 (rank : 344)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	29	Target Neighborhood Hits	158	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

ADAM9_MOUSE
NC score	0.070979 (rank : 345)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	29	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

LYAM2_HUMAN
NC score	0.070858 (rank : 346)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	29	Target Neighborhood Hits	394	Shared Neighborhood Hits	16
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

KRA24_HUMAN
NC score	0.070352 (rank : 347)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	29	Target Neighborhood Hits	192	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

SPR2B_MOUSE
NC score	0.070196 (rank : 348)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	29	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

CELR2_MOUSE
NC score	0.070193 (rank : 349)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	29	Target Neighborhood Hits	584	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

TNR14_HUMAN
NC score	0.070078 (rank : 350)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	29	Target Neighborhood Hits	149	Shared Neighborhood Hits	13
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

RSPO4_HUMAN
NC score	0.069693 (rank : 351)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	29	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

TSP2_HUMAN
NC score	0.067949 (rank : 352)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	29	Target Neighborhood Hits	359	Shared Neighborhood Hits	17
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

NET1_HUMAN
NC score	0.067505 (rank : 353)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	29	Target Neighborhood Hits	149	Shared Neighborhood Hits	14
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

MAP4_HUMAN
NC score	0.067222 (rank : 354)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	29	Target Neighborhood Hits	428	Shared Neighborhood Hits	4
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

FSTL3_MOUSE
NC score	0.066985 (rank : 355)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	29	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

ADA33_MOUSE
NC score	0.066535 (rank : 356)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	29	Target Neighborhood Hits	231	Shared Neighborhood Hits	18
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

NET1_MOUSE
NC score	0.066215 (rank : 357)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	29	Target Neighborhood Hits	151	Shared Neighborhood Hits	14
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

ADA18_MOUSE
NC score	0.065606 (rank : 358)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	29	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ASTN_MOUSE
NC score	0.065252 (rank : 359)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	29	Target Neighborhood Hits	98	Shared Neighborhood Hits	12
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

LYAM1_MOUSE
NC score	0.064970 (rank : 360)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	29	Target Neighborhood Hits	332	Shared Neighborhood Hits	16
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

ADA11_MOUSE
NC score	0.064743 (rank : 361)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	29	Target Neighborhood Hits	263	Shared Neighborhood Hits	18
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

KRA42_HUMAN
NC score	0.064536 (rank : 362)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	29	Target Neighborhood Hits	149	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

ADA11_HUMAN
NC score	0.063932 (rank : 363)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	29	Target Neighborhood Hits	259	Shared Neighborhood Hits	18
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

MT1G_HUMAN
NC score	0.063880 (rank : 364)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	29	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

INSRR_MOUSE
NC score	0.063754 (rank : 365)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	29	Target Neighborhood Hits	961	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LRP3_HUMAN
NC score	0.063440 (rank : 366)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	29	Target Neighborhood Hits	280	Shared Neighborhood Hits	13
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

INSRR_HUMAN
NC score	0.063005 (rank : 367)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	29	Target Neighborhood Hits	950	Shared Neighborhood Hits	15
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

ADA15_HUMAN
NC score	0.062632 (rank : 368)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	29	Target Neighborhood Hits	288	Shared Neighborhood Hits	19
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

WFDC3_HUMAN
NC score	0.061228 (rank : 369)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	29	Target Neighborhood Hits	138	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WISP2_MOUSE
NC score	0.060859 (rank : 370)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	29	Target Neighborhood Hits	129	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ADA32_HUMAN
NC score	0.060781 (rank : 371)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	29	Target Neighborhood Hits	216	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ERBB3_HUMAN
NC score	0.060653 (rank : 372)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	29	Target Neighborhood Hits	918	Shared Neighborhood Hits	13
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

MT1_MOUSE
NC score	0.060506 (rank : 373)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	29	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

RSPO4_MOUSE
NC score	0.060357 (rank : 374)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	29	Target Neighborhood Hits	110	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

HGFA_MOUSE
NC score	0.059891 (rank : 375)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	29	Target Neighborhood Hits	419	Shared Neighborhood Hits	19
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ERBB4_HUMAN
NC score	0.059734 (rank : 376)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	29	Target Neighborhood Hits	910	Shared Neighborhood Hits	14
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

CT127_HUMAN
NC score	0.059604 (rank : 377)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	29	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

ERBB3_MOUSE
NC score	0.059591 (rank : 378)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	29	Target Neighborhood Hits	898	Shared Neighborhood Hits	12
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

KR122_HUMAN
NC score	0.059292 (rank : 379)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	29	Target Neighborhood Hits	97	Shared Neighborhood Hits	8
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

PROC_MOUSE
NC score	0.059232 (rank : 380)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	29	Target Neighborhood Hits	426	Shared Neighborhood Hits	19
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

LRP10_MOUSE
NC score	0.059067 (rank : 381)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	29	Target Neighborhood Hits	169	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

TNR9_HUMAN
NC score	0.059034 (rank : 382)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	29	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

FAT2_HUMAN
NC score	0.058147 (rank : 383)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	29	Target Neighborhood Hits	507	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

ADAM8_MOUSE
NC score	0.058128 (rank : 384)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	29	Target Neighborhood Hits	326	Shared Neighborhood Hits	15
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

EPHB4_HUMAN
NC score	0.058074 (rank : 385)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	29	Target Neighborhood Hits	1056	Shared Neighborhood Hits	14
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

ADA32_MOUSE
NC score	0.057786 (rank : 386)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	29	Target Neighborhood Hits	219	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

HGFA_HUMAN
NC score	0.057764 (rank : 387)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	29	Target Neighborhood Hits	436	Shared Neighborhood Hits	19
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

FSTL3_HUMAN
NC score	0.057640 (rank : 388)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	29	Target Neighborhood Hits	162	Shared Neighborhood Hits	10
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

LRP10_HUMAN
NC score	0.057474 (rank : 389)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	29	Target Neighborhood Hits	197	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

CYR61_HUMAN
NC score	0.056928 (rank : 390)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	29	Target Neighborhood Hits	159	Shared Neighborhood Hits	10
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

ADM1B_MOUSE
NC score	0.056816 (rank : 391)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	29	Target Neighborhood Hits	236	Shared Neighborhood Hits	18
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

FLT3_MOUSE
NC score	0.056798 (rank : 392)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	29	Target Neighborhood Hits	847	Shared Neighborhood Hits	3
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

IGF1R_MOUSE
NC score	0.056688 (rank : 393)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	29	Target Neighborhood Hits	973	Shared Neighborhood Hits	13
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

ODFP_MOUSE
NC score	0.056638 (rank : 394)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	29	Target Neighborhood Hits	75	Shared Neighborhood Hits	10
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

FA9_HUMAN
NC score	0.056572 (rank : 395)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	29	Target Neighborhood Hits	421	Shared Neighborhood Hits	19
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

ADA18_HUMAN
NC score	0.056485 (rank : 396)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	29	Target Neighborhood Hits	184	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

CYR61_MOUSE
NC score	0.056371 (rank : 397)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	29	Target Neighborhood Hits	156	Shared Neighborhood Hits	10
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

CO8B_MOUSE
NC score	0.056325 (rank : 398)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	29	Target Neighborhood Hits	224	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

FA12_HUMAN
NC score	0.056155 (rank : 399)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	29	Target Neighborhood Hits	425	Shared Neighborhood Hits	20
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

CORIN_MOUSE
NC score	0.056084 (rank : 400)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	29	Target Neighborhood Hits	451	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

INSR_HUMAN
NC score	0.055933 (rank : 401)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	29	Target Neighborhood Hits	963	Shared Neighborhood Hits	13
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

RYK_HUMAN
NC score	0.055889 (rank : 402)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	29	Target Neighborhood Hits	701	Shared Neighborhood Hits	3
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

FLT3_HUMAN
NC score	0.055877 (rank : 403)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	29	Target Neighborhood Hits	843	Shared Neighborhood Hits	3
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

ADM1A_MOUSE
NC score	0.055829 (rank : 404)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	29	Target Neighborhood Hits	230	Shared Neighborhood Hits	18
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

IGF1R_HUMAN
NC score	0.055414 (rank : 405)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	29	Target Neighborhood Hits	977	Shared Neighborhood Hits	12
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

ADA10_HUMAN
NC score	0.055295 (rank : 406)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	29	Target Neighborhood Hits	189	Shared Neighborhood Hits	13
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

MT1B_HUMAN
NC score	0.055269 (rank : 407)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	29	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

PTPRU_HUMAN
NC score	0.055203 (rank : 408)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	29	Target Neighborhood Hits	237	Shared Neighborhood Hits	5
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

CSF1R_HUMAN
NC score	0.055108 (rank : 409)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	29	Target Neighborhood Hits	943	Shared Neighborhood Hits	3
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

PGCB_MOUSE
NC score	0.055071 (rank : 410)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	29	Target Neighborhood Hits	459	Shared Neighborhood Hits	11
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

ASTN_HUMAN
NC score	0.055028 (rank : 411)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	29	Target Neighborhood Hits	105	Shared Neighborhood Hits	11
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

RYK_MOUSE
NC score	0.055019 (rank : 412)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	29	Target Neighborhood Hits	715	Shared Neighborhood Hits	3
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

STYK1_HUMAN
NC score	0.054901 (rank : 413)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	29	Target Neighborhood Hits	786	Shared Neighborhood Hits	3
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

EGFR_HUMAN
NC score	0.054371 (rank : 414)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	29	Target Neighborhood Hits	939	Shared Neighborhood Hits	14
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

CSF1R_MOUSE
NC score	0.054265 (rank : 415)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	29	Target Neighborhood Hits	983	Shared Neighborhood Hits	3
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

LYAM1_HUMAN
NC score	0.054170 (rank : 416)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	29	Target Neighborhood Hits	315	Shared Neighborhood Hits	14
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

RET_HUMAN
NC score	0.054152 (rank : 417)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	29	Target Neighborhood Hits	873	Shared Neighborhood Hits	5
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

KR221_HUMAN
NC score	0.054115 (rank : 418)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	29	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q3MIV0	Gene names	KRTAP22-1, KAP22.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 22-1.

ERBB2_MOUSE
NC score	0.054086 (rank : 419)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	29	Target Neighborhood Hits	918	Shared Neighborhood Hits	11
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

EGFR_MOUSE
NC score	0.053909 (rank : 420)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	29	Target Neighborhood Hits	927	Shared Neighborhood Hits	14
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EPHAA_HUMAN
NC score	0.053332 (rank : 421)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	29	Target Neighborhood Hits	960	Shared Neighborhood Hits	13
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

INSR_MOUSE
NC score	0.053042 (rank : 422)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	29	Target Neighborhood Hits	968	Shared Neighborhood Hits	12
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

RET_MOUSE
NC score	0.053033 (rank : 423)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	29	Target Neighborhood Hits	884	Shared Neighborhood Hits	5
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

EPHB4_MOUSE
NC score	0.052723 (rank : 424)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	29	Target Neighborhood Hits	1013	Shared Neighborhood Hits	15
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

STYK1_MOUSE
NC score	0.052659 (rank : 425)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	29	Target Neighborhood Hits	779	Shared Neighborhood Hits	3
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

TNR7_MOUSE
NC score	0.052573 (rank : 426)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	29	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

ADA23_HUMAN
NC score	0.052465 (rank : 427)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	29	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ERBB2_HUMAN
NC score	0.052123 (rank : 428)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	29	Target Neighborhood Hits	1073	Shared Neighborhood Hits	10
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

MT1A_HUMAN
NC score	0.052112 (rank : 429)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	29	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

KIT_MOUSE
NC score	0.051940 (rank : 430)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	29	Target Neighborhood Hits	949	Shared Neighborhood Hits	3
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

ADA30_HUMAN
NC score	0.051846 (rank : 431)	θ value	8.99809 (rank : 26)
Query Neighborhood Hits	29	Target Neighborhood Hits	391	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

MUC13_MOUSE
NC score	0.051716 (rank : 432)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	29	Target Neighborhood Hits	447	Shared Neighborhood Hits	14
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

EPHA1_HUMAN
NC score	0.051629 (rank : 433)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	29	Target Neighborhood Hits	997	Shared Neighborhood Hits	14
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

MT2_MOUSE
NC score	0.051367 (rank : 434)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	29	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

VGFR3_HUMAN
NC score	0.051063 (rank : 435)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	29	Target Neighborhood Hits	1037	Shared Neighborhood Hits	3
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

PAPPA_MOUSE
NC score	0.051013 (rank : 436)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	29	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PGCA_HUMAN
NC score	0.051005 (rank : 437)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	29	Target Neighborhood Hits	821	Shared Neighborhood Hits	16
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

MDC1_HUMAN
NC score	0.051001 (rank : 438)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	29	Target Neighborhood Hits	1446	Shared Neighborhood Hits	6
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

VGFR3_MOUSE
NC score	0.050921 (rank : 439)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	29	Target Neighborhood Hits	1056	Shared Neighborhood Hits	3
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

EPHB6_HUMAN
NC score	0.050605 (rank : 440)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	29	Target Neighborhood Hits	912	Shared Neighborhood Hits	12
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

ADA10_MOUSE
NC score	0.050591 (rank : 441)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	29	Target Neighborhood Hits	194	Shared Neighborhood Hits	13
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ALK_HUMAN
NC score	0.050479 (rank : 442)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	29	Target Neighborhood Hits	795	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

PGCB_HUMAN
NC score	0.050447 (rank : 443)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	29	Target Neighborhood Hits	478	Shared Neighborhood Hits	12
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

ALK_MOUSE
NC score	0.050317 (rank : 444)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	29	Target Neighborhood Hits	811	Shared Neighborhood Hits	7
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

LTK_MOUSE
NC score	0.050316 (rank : 445)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	29	Target Neighborhood Hits	770	Shared Neighborhood Hits	6
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

KIT_HUMAN
NC score	0.050281 (rank : 446)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	29	Target Neighborhood Hits	953	Shared Neighborhood Hits	3
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

WISP2_HUMAN
NC score	0.050281 (rank : 447)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	29	Target Neighborhood Hits	126	Shared Neighborhood Hits	7
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

PGFRB_HUMAN
NC score	0.050146 (rank : 448)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	29	Target Neighborhood Hits	962	Shared Neighborhood Hits	3
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRB_MOUSE
NC score	0.050019 (rank : 449)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	29	Target Neighborhood Hits	960	Shared Neighborhood Hits	3
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

ADA17_HUMAN
NC score	0.050010 (rank : 450)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	29	Target Neighborhood Hits	223	Shared Neighborhood Hits	14
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

UBP36_HUMAN
NC score	0.020855 (rank : 451)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	29	Target Neighborhood Hits	232	Shared Neighborhood Hits	1
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

K1H5_HUMAN
NC score	0.009603 (rank : 452)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	29	Target Neighborhood Hits	362	Shared Neighborhood Hits	1
SwissProt Accessions	Q92764, O76012, Q92651	Gene names	KRTHA5, HHA5, HKA5
Domain Architecture
Description	Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5).