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Network neighborhood for query Sequence : PCSK5_HUMAN

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PCSK5_HUMAN
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FURIN_HUMAN
θ value	0 (rank : 1)	NC score	0.890952 (rank : 5)
Query Neighborhood Hits	291	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

PCSK5_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	291	Target Neighborhood Hits	291	Shared Neighborhood Hits	291
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK5_MOUSE
θ value	0 (rank : 3)	NC score	0.907094 (rank : 3)
Query Neighborhood Hits	291	Target Neighborhood Hits	613	Shared Neighborhood Hits	270
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK6_HUMAN
θ value	0 (rank : 4)	NC score	0.958747 (rank : 2)
Query Neighborhood Hits	291	Target Neighborhood Hits	298	Shared Neighborhood Hits	177
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

FURIN_MOUSE
θ value	5.00115e-184 (rank : 5)	NC score	0.892481 (rank : 4)
Query Neighborhood Hits	291	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

PCSK4_HUMAN
θ value	2.17943e-171 (rank : 6)	NC score	0.879181 (rank : 6)
Query Neighborhood Hits	291	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PCSK4_MOUSE
θ value	1.79118e-157 (rank : 7)	NC score	0.866352 (rank : 7)
Query Neighborhood Hits	291	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

NEC1_HUMAN
θ value	1.16101e-156 (rank : 8)	NC score	0.862666 (rank : 9)
Query Neighborhood Hits	291	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

NEC1_MOUSE
θ value	2.18956e-155 (rank : 9)	NC score	0.862701 (rank : 8)
Query Neighborhood Hits	291	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	P63239, P21662, P22546	Gene names	Pcsk1, Att-1, Nec-1, Nec1
Domain Architecture	No domain graphic available
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1) (PC3) (Furin homolog) (Propeptide-processing protease).

NEC2_MOUSE
θ value	1.92707e-135 (rank : 10)	NC score	0.859375 (rank : 10)
Query Neighborhood Hits	291	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P21661, Q80WU1	Gene names	Pcsk2, Nec-2, Nec2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NEC2_HUMAN
θ value	7.32286e-135 (rank : 11)	NC score	0.859147 (rank : 11)
Query Neighborhood Hits	291	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P16519, Q14927, Q9NQG3, Q9NUG1, Q9UJC6	Gene names	PCSK2, NEC2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

PCSK7_MOUSE
θ value	8.39787e-123 (rank : 12)	NC score	0.852362 (rank : 13)
Query Neighborhood Hits	291	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

PCSK7_HUMAN
θ value	5.44333e-122 (rank : 13)	NC score	0.852512 (rank : 12)
Query Neighborhood Hits	291	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

FRAS1_MOUSE
θ value	4.72714e-33 (rank : 14)	NC score	0.406059 (rank : 15)
Query Neighborhood Hits	291	Target Neighborhood Hits	747	Shared Neighborhood Hits	235
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_HUMAN
θ value	8.06329e-33 (rank : 15)	NC score	0.411178 (rank : 14)
Query Neighborhood Hits	291	Target Neighborhood Hits	759	Shared Neighborhood Hits	229
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ERBB3_HUMAN
θ value	2.98157e-11 (rank : 16)	NC score	0.117496 (rank : 296)
Query Neighborhood Hits	291	Target Neighborhood Hits	918	Shared Neighborhood Hits	84
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

MEGF9_MOUSE
θ value	3.89403e-11 (rank : 17)	NC score	0.313632 (rank : 28)
Query Neighborhood Hits	291	Target Neighborhood Hits	896	Shared Neighborhood Hits	181
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ERBB3_MOUSE
θ value	8.67504e-11 (rank : 18)	NC score	0.115454 (rank : 300)
Query Neighborhood Hits	291	Target Neighborhood Hits	898	Shared Neighborhood Hits	76
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB2_MOUSE
θ value	5.62301e-10 (rank : 19)	NC score	0.102964 (rank : 332)
Query Neighborhood Hits	291	Target Neighborhood Hits	918	Shared Neighborhood Hits	68
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB4_HUMAN
θ value	1.63604e-09 (rank : 20)	NC score	0.105620 (rank : 327)
Query Neighborhood Hits	291	Target Neighborhood Hits	910	Shared Neighborhood Hits	75
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

RSPO1_HUMAN
θ value	8.11959e-09 (rank : 21)	NC score	0.306858 (rank : 32)
Query Neighborhood Hits	291	Target Neighborhood Hits	101	Shared Neighborhood Hits	64
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

MEGF9_HUMAN
θ value	1.06045e-08 (rank : 22)	NC score	0.322226 (rank : 22)
Query Neighborhood Hits	291	Target Neighborhood Hits	557	Shared Neighborhood Hits	184
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

ERBB2_HUMAN
θ value	1.80886e-08 (rank : 23)	NC score	0.102525 (rank : 333)
Query Neighborhood Hits	291	Target Neighborhood Hits	1073	Shared Neighborhood Hits	68
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

CREL1_MOUSE
θ value	3.08544e-08 (rank : 24)	NC score	0.341020 (rank : 17)
Query Neighborhood Hits	291	Target Neighborhood Hits	524	Shared Neighborhood Hits	193
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LAMB1_MOUSE
θ value	5.26297e-08 (rank : 25)	NC score	0.255983 (rank : 65)
Query Neighborhood Hits	291	Target Neighborhood Hits	919	Shared Neighborhood Hits	173
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

RSPO1_MOUSE
θ value	5.26297e-08 (rank : 26)	NC score	0.288568 (rank : 37)
Query Neighborhood Hits	291	Target Neighborhood Hits	85	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO3_MOUSE
θ value	5.26297e-08 (rank : 27)	NC score	0.333171 (rank : 19)
Query Neighborhood Hits	291	Target Neighborhood Hits	120	Shared Neighborhood Hits	78
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

MATN2_HUMAN
θ value	8.97725e-08 (rank : 28)	NC score	0.237803 (rank : 89)
Query Neighborhood Hits	291	Target Neighborhood Hits	365	Shared Neighborhood Hits	161
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

RSPO3_HUMAN
θ value	8.97725e-08 (rank : 29)	NC score	0.338720 (rank : 18)
Query Neighborhood Hits	291	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO2_MOUSE
θ value	1.17247e-07 (rank : 30)	NC score	0.313621 (rank : 29)
Query Neighborhood Hits	291	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

CREL1_HUMAN
θ value	1.53129e-07 (rank : 31)	NC score	0.343455 (rank : 16)
Query Neighborhood Hits	291	Target Neighborhood Hits	441	Shared Neighborhood Hits	181
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

RSPO4_HUMAN
θ value	1.53129e-07 (rank : 32)	NC score	0.327876 (rank : 20)
Query Neighborhood Hits	291	Target Neighborhood Hits	110	Shared Neighborhood Hits	77
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO2_HUMAN
θ value	1.99992e-07 (rank : 33)	NC score	0.313270 (rank : 30)
Query Neighborhood Hits	291	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

EGFR_HUMAN
θ value	2.61198e-07 (rank : 34)	NC score	0.099278 (rank : 345)
Query Neighborhood Hits	291	Target Neighborhood Hits	939	Shared Neighborhood Hits	86
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	3.41135e-07 (rank : 35)	NC score	0.100859 (rank : 339)
Query Neighborhood Hits	291	Target Neighborhood Hits	927	Shared Neighborhood Hits	92
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

IGF1R_MOUSE
θ value	3.41135e-07 (rank : 36)	NC score	0.094341 (rank : 361)
Query Neighborhood Hits	291	Target Neighborhood Hits	973	Shared Neighborhood Hits	95
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

LAMA5_MOUSE
θ value	4.45536e-07 (rank : 37)	NC score	0.271839 (rank : 43)
Query Neighborhood Hits	291	Target Neighborhood Hits	828	Shared Neighborhood Hits	211
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NELL2_HUMAN
θ value	5.81887e-07 (rank : 38)	NC score	0.271321 (rank : 44)
Query Neighborhood Hits	291	Target Neighborhood Hits	449	Shared Neighborhood Hits	178
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

INSRR_HUMAN
θ value	1.69304e-06 (rank : 39)	NC score	0.096416 (rank : 354)
Query Neighborhood Hits	291	Target Neighborhood Hits	950	Shared Neighborhood Hits	101
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

NELL2_MOUSE
θ value	2.88788e-06 (rank : 40)	NC score	0.269994 (rank : 46)
Query Neighborhood Hits	291	Target Neighborhood Hits	436	Shared Neighborhood Hits	176
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

RSPO4_MOUSE
θ value	4.92598e-06 (rank : 41)	NC score	0.325047 (rank : 21)
Query Neighborhood Hits	291	Target Neighborhood Hits	110	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SREC2_MOUSE
θ value	4.92598e-06 (rank : 42)	NC score	0.319812 (rank : 23)
Query Neighborhood Hits	291	Target Neighborhood Hits	605	Shared Neighborhood Hits	202
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

INSRR_MOUSE
θ value	6.43352e-06 (rank : 43)	NC score	0.095549 (rank : 356)
Query Neighborhood Hits	291	Target Neighborhood Hits	961	Shared Neighborhood Hits	113
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LAMA2_MOUSE
θ value	6.43352e-06 (rank : 44)	NC score	0.235337 (rank : 95)
Query Neighborhood Hits	291	Target Neighborhood Hits	1198	Shared Neighborhood Hits	197
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

PGBM_MOUSE
θ value	6.43352e-06 (rank : 45)	NC score	0.183508 (rank : 187)
Query Neighborhood Hits	291	Target Neighborhood Hits	1073	Shared Neighborhood Hits	201
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MEGF8_MOUSE
θ value	8.40245e-06 (rank : 46)	NC score	0.303741 (rank : 33)
Query Neighborhood Hits	291	Target Neighborhood Hits	520	Shared Neighborhood Hits	186
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

IGF1R_HUMAN
θ value	1.09739e-05 (rank : 47)	NC score	0.091242 (rank : 373)
Query Neighborhood Hits	291	Target Neighborhood Hits	977	Shared Neighborhood Hits	90
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

MEGF8_HUMAN
θ value	1.43324e-05 (rank : 48)	NC score	0.307263 (rank : 31)
Query Neighborhood Hits	291	Target Neighborhood Hits	528	Shared Neighborhood Hits	187
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SCUB3_HUMAN
θ value	1.87187e-05 (rank : 49)	NC score	0.265540 (rank : 53)
Query Neighborhood Hits	291	Target Neighborhood Hits	428	Shared Neighborhood Hits	197
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMB1_HUMAN
θ value	2.44474e-05 (rank : 50)	NC score	0.243498 (rank : 75)
Query Neighborhood Hits	291	Target Neighborhood Hits	1018	Shared Neighborhood Hits	176
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

INSR_HUMAN
θ value	3.19293e-05 (rank : 51)	NC score	0.088102 (rank : 380)
Query Neighborhood Hits	291	Target Neighborhood Hits	963	Shared Neighborhood Hits	90
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

LAMA1_MOUSE
θ value	3.19293e-05 (rank : 52)	NC score	0.270637 (rank : 45)
Query Neighborhood Hits	291	Target Neighborhood Hits	838	Shared Neighborhood Hits	208
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

SCUB3_MOUSE
θ value	3.19293e-05 (rank : 53)	NC score	0.266068 (rank : 52)
Query Neighborhood Hits	291	Target Neighborhood Hits	442	Shared Neighborhood Hits	199
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

USH2A_MOUSE
θ value	3.19293e-05 (rank : 54)	NC score	0.251243 (rank : 70)
Query Neighborhood Hits	291	Target Neighborhood Hits	626	Shared Neighborhood Hits	188
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

SREC_HUMAN
θ value	4.1701e-05 (rank : 55)	NC score	0.315991 (rank : 24)
Query Neighborhood Hits	291	Target Neighborhood Hits	645	Shared Neighborhood Hits	207
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

VWF_MOUSE
θ value	4.1701e-05 (rank : 56)	NC score	0.185535 (rank : 182)
Query Neighborhood Hits	291	Target Neighborhood Hits	381	Shared Neighborhood Hits	152
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

HMCN1_HUMAN
θ value	5.44631e-05 (rank : 57)	NC score	0.153246 (rank : 237)
Query Neighborhood Hits	291	Target Neighborhood Hits	983	Shared Neighborhood Hits	181
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

MATN2_MOUSE
θ value	7.1131e-05 (rank : 58)	NC score	0.234568 (rank : 98)
Query Neighborhood Hits	291	Target Neighborhood Hits	356	Shared Neighborhood Hits	160
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MEGF6_HUMAN
θ value	9.29e-05 (rank : 59)	NC score	0.315535 (rank : 25)
Query Neighborhood Hits	291	Target Neighborhood Hits	671	Shared Neighborhood Hits	230
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

INSR_MOUSE
θ value	0.000121331 (rank : 60)	NC score	0.087679 (rank : 381)
Query Neighborhood Hits	291	Target Neighborhood Hits	968	Shared Neighborhood Hits	79
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

FBN2_MOUSE
θ value	0.00020696 (rank : 61)	NC score	0.254880 (rank : 66)
Query Neighborhood Hits	291	Target Neighborhood Hits	549	Shared Neighborhood Hits	202
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LAMC2_HUMAN
θ value	0.000270298 (rank : 62)	NC score	0.237270 (rank : 91)
Query Neighborhood Hits	291	Target Neighborhood Hits	715	Shared Neighborhood Hits	176
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

PGBM_HUMAN
θ value	0.000270298 (rank : 63)	NC score	0.175784 (rank : 197)
Query Neighborhood Hits	291	Target Neighborhood Hits	1113	Shared Neighborhood Hits	194
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

DLL1_MOUSE
θ value	0.00035302 (rank : 64)	NC score	0.236685 (rank : 92)
Query Neighborhood Hits	291	Target Neighborhood Hits	456	Shared Neighborhood Hits	181
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

LAMA1_HUMAN
θ value	0.00035302 (rank : 65)	NC score	0.269612 (rank : 47)
Query Neighborhood Hits	291	Target Neighborhood Hits	804	Shared Neighborhood Hits	204
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC1_HUMAN
θ value	0.00035302 (rank : 66)	NC score	0.241378 (rank : 82)
Query Neighborhood Hits	291	Target Neighborhood Hits	922	Shared Neighborhood Hits	178
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

NELL1_HUMAN
θ value	0.00035302 (rank : 67)	NC score	0.275766 (rank : 39)
Query Neighborhood Hits	291	Target Neighborhood Hits	451	Shared Neighborhood Hits	186
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

ZAN_MOUSE
θ value	0.00035302 (rank : 68)	NC score	0.275301 (rank : 40)
Query Neighborhood Hits	291	Target Neighborhood Hits	808	Shared Neighborhood Hits	228
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CUBN_MOUSE
θ value	0.000461057 (rank : 69)	NC score	0.205624 (rank : 147)
Query Neighborhood Hits	291	Target Neighborhood Hits	477	Shared Neighborhood Hits	175
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

FBN2_HUMAN
θ value	0.000461057 (rank : 70)	NC score	0.257645 (rank : 62)
Query Neighborhood Hits	291	Target Neighborhood Hits	560	Shared Neighborhood Hits	198
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

LAMB3_HUMAN
θ value	0.000461057 (rank : 71)	NC score	0.235656 (rank : 94)
Query Neighborhood Hits	291	Target Neighborhood Hits	461	Shared Neighborhood Hits	137
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LTBP2_MOUSE
θ value	0.000461057 (rank : 72)	NC score	0.261038 (rank : 55)
Query Neighborhood Hits	291	Target Neighborhood Hits	617	Shared Neighborhood Hits	195
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBLN5_MOUSE
θ value	0.000602161 (rank : 73)	NC score	0.230328 (rank : 105)
Query Neighborhood Hits	291	Target Neighborhood Hits	317	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LAMA2_HUMAN
θ value	0.000602161 (rank : 74)	NC score	0.247050 (rank : 72)
Query Neighborhood Hits	291	Target Neighborhood Hits	1092	Shared Neighborhood Hits	201
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC3_HUMAN
θ value	0.000602161 (rank : 75)	NC score	0.272383 (rank : 42)
Query Neighborhood Hits	291	Target Neighborhood Hits	588	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CUBN_HUMAN
θ value	0.000786445 (rank : 76)	NC score	0.208728 (rank : 142)
Query Neighborhood Hits	291	Target Neighborhood Hits	482	Shared Neighborhood Hits	168
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

LAMC3_MOUSE
θ value	0.000786445 (rank : 77)	NC score	0.268632 (rank : 49)
Query Neighborhood Hits	291	Target Neighborhood Hits	624	Shared Neighborhood Hits	194
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MATN4_MOUSE
θ value	0.000786445 (rank : 78)	NC score	0.188450 (rank : 172)
Query Neighborhood Hits	291	Target Neighborhood Hits	277	Shared Neighborhood Hits	134
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

USH2A_HUMAN
θ value	0.000786445 (rank : 79)	NC score	0.233700 (rank : 100)
Query Neighborhood Hits	291	Target Neighborhood Hits	600	Shared Neighborhood Hits	184
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

DLL1_HUMAN
θ value	0.00102713 (rank : 80)	NC score	0.232313 (rank : 103)
Query Neighborhood Hits	291	Target Neighborhood Hits	455	Shared Neighborhood Hits	180
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL3_HUMAN
θ value	0.00102713 (rank : 81)	NC score	0.217823 (rank : 124)
Query Neighborhood Hits	291	Target Neighborhood Hits	419	Shared Neighborhood Hits	156
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

MATN3_HUMAN
θ value	0.00102713 (rank : 82)	NC score	0.192221 (rank : 162)
Query Neighborhood Hits	291	Target Neighborhood Hits	268	Shared Neighborhood Hits	125
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

STAB1_HUMAN
θ value	0.00102713 (rank : 83)	NC score	0.259655 (rank : 58)
Query Neighborhood Hits	291	Target Neighborhood Hits	546	Shared Neighborhood Hits	193
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

LRP2_HUMAN
θ value	0.00134147 (rank : 84)	NC score	0.194999 (rank : 158)
Query Neighborhood Hits	291	Target Neighborhood Hits	573	Shared Neighborhood Hits	188
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

NID2_HUMAN
θ value	0.00134147 (rank : 85)	NC score	0.213350 (rank : 135)
Query Neighborhood Hits	291	Target Neighborhood Hits	456	Shared Neighborhood Hits	163
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

STAB1_MOUSE
θ value	0.00134147 (rank : 86)	NC score	0.259385 (rank : 60)
Query Neighborhood Hits	291	Target Neighborhood Hits	566	Shared Neighborhood Hits	192
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TIE2_MOUSE
θ value	0.00134147 (rank : 87)	NC score	0.105750 (rank : 326)
Query Neighborhood Hits	291	Target Neighborhood Hits	1204	Shared Neighborhood Hits	171
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TNR1A_MOUSE
θ value	0.00134147 (rank : 88)	NC score	0.137547 (rank : 265)
Query Neighborhood Hits	291	Target Neighborhood Hits	131	Shared Neighborhood Hits	66
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

LAMB2_MOUSE
θ value	0.00175202 (rank : 89)	NC score	0.268777 (rank : 48)
Query Neighborhood Hits	291	Target Neighborhood Hits	722	Shared Neighborhood Hits	183
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

VWF_HUMAN
θ value	0.00175202 (rank : 90)	NC score	0.184600 (rank : 183)
Query Neighborhood Hits	291	Target Neighborhood Hits	396	Shared Neighborhood Hits	156
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CRIM1_HUMAN
θ value	0.00228821 (rank : 91)	NC score	0.261957 (rank : 54)
Query Neighborhood Hits	291	Target Neighborhood Hits	362	Shared Neighborhood Hits	151
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ITB7_MOUSE
θ value	0.00228821 (rank : 92)	NC score	0.186050 (rank : 181)
Query Neighborhood Hits	291	Target Neighborhood Hits	277	Shared Neighborhood Hits	144
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

LAMB2_HUMAN
θ value	0.00228821 (rank : 93)	NC score	0.274769 (rank : 41)
Query Neighborhood Hits	291	Target Neighborhood Hits	692	Shared Neighborhood Hits	182
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMC2_MOUSE
θ value	0.00228821 (rank : 94)	NC score	0.254454 (rank : 67)
Query Neighborhood Hits	291	Target Neighborhood Hits	614	Shared Neighborhood Hits	190
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

TNR9_HUMAN
θ value	0.00228821 (rank : 95)	NC score	0.139699 (rank : 263)
Query Neighborhood Hits	291	Target Neighborhood Hits	166	Shared Neighborhood Hits	97
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TSP1_HUMAN
θ value	0.00228821 (rank : 96)	NC score	0.165699 (rank : 215)
Query Neighborhood Hits	291	Target Neighborhood Hits	389	Shared Neighborhood Hits	162
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

FBN1_HUMAN
θ value	0.00390308 (rank : 97)	NC score	0.258713 (rank : 61)
Query Neighborhood Hits	291	Target Neighborhood Hits	557	Shared Neighborhood Hits	204
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

ITB3_MOUSE
θ value	0.00390308 (rank : 98)	NC score	0.183537 (rank : 186)
Query Neighborhood Hits	291	Target Neighborhood Hits	319	Shared Neighborhood Hits	162
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

SREC2_HUMAN
θ value	0.00390308 (rank : 99)	NC score	0.313780 (rank : 27)
Query Neighborhood Hits	291	Target Neighborhood Hits	645	Shared Neighborhood Hits	199
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TNR9_MOUSE
θ value	0.00390308 (rank : 100)	NC score	0.157977 (rank : 227)
Query Neighborhood Hits	291	Target Neighborhood Hits	137	Shared Neighborhood Hits	82
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TRBM_MOUSE
θ value	0.00390308 (rank : 101)	NC score	0.230789 (rank : 104)
Query Neighborhood Hits	291	Target Neighborhood Hits	361	Shared Neighborhood Hits	161
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP1_MOUSE
θ value	0.00390308 (rank : 102)	NC score	0.164094 (rank : 217)
Query Neighborhood Hits	291	Target Neighborhood Hits	396	Shared Neighborhood Hits	164
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

LAMC1_MOUSE
θ value	0.00509761 (rank : 103)	NC score	0.244592 (rank : 73)
Query Neighborhood Hits	291	Target Neighborhood Hits	856	Shared Neighborhood Hits	182
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

FA76B_HUMAN
θ value	0.00665767 (rank : 104)	NC score	0.063746 (rank : 445)
Query Neighborhood Hits	291	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FA76B_MOUSE
θ value	0.00665767 (rank : 105)	NC score	0.080366 (rank : 398)
Query Neighborhood Hits	291	Target Neighborhood Hits	181	Shared Neighborhood Hits	13
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

FBLN1_HUMAN
θ value	0.00665767 (rank : 106)	NC score	0.234637 (rank : 97)
Query Neighborhood Hits	291	Target Neighborhood Hits	324	Shared Neighborhood Hits	158
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

ITB1_HUMAN
θ value	0.00665767 (rank : 107)	NC score	0.175226 (rank : 198)
Query Neighborhood Hits	291	Target Neighborhood Hits	298	Shared Neighborhood Hits	152
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

NOTC1_MOUSE
θ value	0.00665767 (rank : 108)	NC score	0.239175 (rank : 84)
Query Neighborhood Hits	291	Target Neighborhood Hits	916	Shared Neighborhood Hits	195
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

TECTA_MOUSE
θ value	0.00665767 (rank : 109)	NC score	0.141445 (rank : 257)
Query Neighborhood Hits	291	Target Neighborhood Hits	244	Shared Neighborhood Hits	121
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

BMPER_MOUSE
θ value	0.00869519 (rank : 110)	NC score	0.166624 (rank : 213)
Query Neighborhood Hits	291	Target Neighborhood Hits	194	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

FBLN2_MOUSE
θ value	0.00869519 (rank : 111)	NC score	0.241435 (rank : 81)
Query Neighborhood Hits	291	Target Neighborhood Hits	505	Shared Neighborhood Hits	167
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN4_MOUSE
θ value	0.00869519 (rank : 112)	NC score	0.215654 (rank : 129)
Query Neighborhood Hits	291	Target Neighborhood Hits	270	Shared Neighborhood Hits	138
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBN1_MOUSE
θ value	0.00869519 (rank : 113)	NC score	0.256991 (rank : 63)
Query Neighborhood Hits	291	Target Neighborhood Hits	563	Shared Neighborhood Hits	202
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

NTNG1_HUMAN
θ value	0.00869519 (rank : 114)	NC score	0.210285 (rank : 140)
Query Neighborhood Hits	291	Target Neighborhood Hits	247	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

STAB2_HUMAN
θ value	0.00869519 (rank : 115)	NC score	0.259838 (rank : 57)
Query Neighborhood Hits	291	Target Neighborhood Hits	534	Shared Neighborhood Hits	192
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

FBLN4_HUMAN
θ value	0.0113563 (rank : 116)	NC score	0.214934 (rank : 132)
Query Neighborhood Hits	291	Target Neighborhood Hits	278	Shared Neighborhood Hits	140
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

JAG2_HUMAN
θ value	0.0113563 (rank : 117)	NC score	0.241547 (rank : 80)
Query Neighborhood Hits	291	Target Neighborhood Hits	491	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

LRP1B_HUMAN
θ value	0.0113563 (rank : 118)	NC score	0.197093 (rank : 154)
Query Neighborhood Hits	291	Target Neighborhood Hits	602	Shared Neighborhood Hits	186
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	0.0113563 (rank : 119)	NC score	0.195605 (rank : 157)
Query Neighborhood Hits	291	Target Neighborhood Hits	606	Shared Neighborhood Hits	183
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LTBP2_HUMAN
θ value	0.0113563 (rank : 120)	NC score	0.252114 (rank : 69)
Query Neighborhood Hits	291	Target Neighborhood Hits	552	Shared Neighborhood Hits	192
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

ITB7_HUMAN
θ value	0.0148317 (rank : 121)	NC score	0.186677 (rank : 177)
Query Neighborhood Hits	291	Target Neighborhood Hits	290	Shared Neighborhood Hits	157
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

STAB2_MOUSE
θ value	0.0148317 (rank : 122)	NC score	0.256858 (rank : 64)
Query Neighborhood Hits	291	Target Neighborhood Hits	528	Shared Neighborhood Hits	192
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TIE1_MOUSE
θ value	0.0148317 (rank : 123)	NC score	0.108160 (rank : 321)
Query Neighborhood Hits	291	Target Neighborhood Hits	1266	Shared Neighborhood Hits	165
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

FBLN1_MOUSE
θ value	0.0193708 (rank : 124)	NC score	0.238837 (rank : 87)
Query Neighborhood Hits	291	Target Neighborhood Hits	329	Shared Neighborhood Hits	164
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	0.0193708 (rank : 125)	NC score	0.243197 (rank : 76)
Query Neighborhood Hits	291	Target Neighborhood Hits	392	Shared Neighborhood Hits	164
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

NOTC1_HUMAN
θ value	0.0193708 (rank : 126)	NC score	0.232908 (rank : 102)
Query Neighborhood Hits	291	Target Neighborhood Hits	906	Shared Neighborhood Hits	196
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ATL3_HUMAN
θ value	0.0252991 (rank : 127)	NC score	0.046311 (rank : 504)
Query Neighborhood Hits	291	Target Neighborhood Hits	414	Shared Neighborhood Hits	40
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

C1QR1_HUMAN
θ value	0.0252991 (rank : 128)	NC score	0.220740 (rank : 118)
Query Neighborhood Hits	291	Target Neighborhood Hits	493	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

ITB3_HUMAN
θ value	0.0252991 (rank : 129)	NC score	0.188734 (rank : 171)
Query Neighborhood Hits	291	Target Neighborhood Hits	325	Shared Neighborhood Hits	171
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

LRP1_HUMAN
θ value	0.0252991 (rank : 130)	NC score	0.203451 (rank : 148)
Query Neighborhood Hits	291	Target Neighborhood Hits	617	Shared Neighborhood Hits	195
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

NOTC2_MOUSE
θ value	0.0252991 (rank : 131)	NC score	0.221507 (rank : 117)
Query Neighborhood Hits	291	Target Neighborhood Hits	1069	Shared Neighborhood Hits	181
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TIE1_HUMAN
θ value	0.0252991 (rank : 132)	NC score	0.112678 (rank : 308)
Query Neighborhood Hits	291	Target Neighborhood Hits	1241	Shared Neighborhood Hits	165
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TNR3_HUMAN
θ value	0.0252991 (rank : 133)	NC score	0.118605 (rank : 295)
Query Neighborhood Hits	291	Target Neighborhood Hits	145	Shared Neighborhood Hits	64
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

ATS17_HUMAN
θ value	0.0330416 (rank : 134)	NC score	0.050300 (rank : 501)
Query Neighborhood Hits	291	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

LAMA5_HUMAN
θ value	0.0330416 (rank : 135)	NC score	0.267610 (rank : 51)
Query Neighborhood Hits	291	Target Neighborhood Hits	976	Shared Neighborhood Hits	214
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

ITB1_MOUSE
θ value	0.0431538 (rank : 136)	NC score	0.177081 (rank : 194)
Query Neighborhood Hits	291	Target Neighborhood Hits	283	Shared Neighborhood Hits	151
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

LAMA3_HUMAN
θ value	0.0431538 (rank : 137)	NC score	0.208164 (rank : 143)
Query Neighborhood Hits	291	Target Neighborhood Hits	760	Shared Neighborhood Hits	168
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA3_MOUSE
θ value	0.0431538 (rank : 138)	NC score	0.229870 (rank : 106)
Query Neighborhood Hits	291	Target Neighborhood Hits	859	Shared Neighborhood Hits	192
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

TNR25_HUMAN
θ value	0.0431538 (rank : 139)	NC score	0.169665 (rank : 208)
Query Neighborhood Hits	291	Target Neighborhood Hits	172	Shared Neighborhood Hits	86
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TR10A_HUMAN
θ value	0.0431538 (rank : 140)	NC score	0.100070 (rank : 341)
Query Neighborhood Hits	291	Target Neighborhood Hits	82	Shared Neighborhood Hits	47
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

AGRIN_HUMAN
θ value	0.0563607 (rank : 141)	NC score	0.225443 (rank : 110)
Query Neighborhood Hits	291	Target Neighborhood Hits	582	Shared Neighborhood Hits	168
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FBN3_HUMAN
θ value	0.0563607 (rank : 142)	NC score	0.259428 (rank : 59)
Query Neighborhood Hits	291	Target Neighborhood Hits	543	Shared Neighborhood Hits	197
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LTB1L_MOUSE
θ value	0.0563607 (rank : 143)	NC score	0.234657 (rank : 96)
Query Neighborhood Hits	291	Target Neighborhood Hits	514	Shared Neighborhood Hits	181
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.0563607 (rank : 144)	NC score	0.235886 (rank : 93)
Query Neighborhood Hits	291	Target Neighborhood Hits	479	Shared Neighborhood Hits	178
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NTNG1_MOUSE
θ value	0.0563607 (rank : 145)	NC score	0.207904 (rank : 145)
Query Neighborhood Hits	291	Target Neighborhood Hits	246	Shared Neighborhood Hits	131
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

SORL_HUMAN
θ value	0.0563607 (rank : 146)	NC score	0.137054 (rank : 267)
Query Neighborhood Hits	291	Target Neighborhood Hits	440	Shared Neighborhood Hits	148
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

ZNFX1_HUMAN
θ value	0.0563607 (rank : 147)	NC score	0.112174 (rank : 310)
Query Neighborhood Hits	291	Target Neighborhood Hits	308	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

DLL4_MOUSE
θ value	0.0736092 (rank : 148)	NC score	0.240226 (rank : 83)
Query Neighborhood Hits	291	Target Neighborhood Hits	440	Shared Neighborhood Hits	177
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

TECTA_HUMAN
θ value	0.0736092 (rank : 149)	NC score	0.129963 (rank : 276)
Query Neighborhood Hits	291	Target Neighborhood Hits	239	Shared Neighborhood Hits	112
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TENR_HUMAN
θ value	0.0736092 (rank : 150)	NC score	0.125199 (rank : 284)
Query Neighborhood Hits	291	Target Neighborhood Hits	526	Shared Neighborhood Hits	157
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ATS19_MOUSE
θ value	0.0961366 (rank : 151)	NC score	0.038098 (rank : 513)
Query Neighborhood Hits	291	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

TNR16_MOUSE
θ value	0.0961366 (rank : 152)	NC score	0.171766 (rank : 203)
Query Neighborhood Hits	291	Target Neighborhood Hits	178	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR26_MOUSE
θ value	0.0961366 (rank : 153)	NC score	0.137255 (rank : 266)
Query Neighborhood Hits	291	Target Neighborhood Hits	106	Shared Neighborhood Hits	72
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

JAG2_MOUSE
θ value	0.125558 (rank : 154)	NC score	0.238631 (rank : 88)
Query Neighborhood Hits	291	Target Neighborhood Hits	504	Shared Neighborhood Hits	173
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KRA53_HUMAN
θ value	0.125558 (rank : 155)	NC score	0.295941 (rank : 35)
Query Neighborhood Hits	291	Target Neighborhood Hits	331	Shared Neighborhood Hits	153
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

NOTC4_MOUSE
θ value	0.125558 (rank : 156)	NC score	0.219014 (rank : 120)
Query Neighborhood Hits	291	Target Neighborhood Hits	872	Shared Neighborhood Hits	187
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PAP2_HUMAN
θ value	0.125558 (rank : 157)	NC score	0.050669 (rank : 495)
Query Neighborhood Hits	291	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

SRCH_HUMAN
θ value	0.125558 (rank : 158)	NC score	0.064294 (rank : 442)
Query Neighborhood Hits	291	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TNR6_MOUSE
θ value	0.125558 (rank : 159)	NC score	0.109574 (rank : 317)
Query Neighborhood Hits	291	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

DLL4_HUMAN
θ value	0.163984 (rank : 160)	NC score	0.233694 (rank : 101)
Query Neighborhood Hits	291	Target Neighborhood Hits	435	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

FA76A_HUMAN
θ value	0.163984 (rank : 161)	NC score	0.055718 (rank : 470)
Query Neighborhood Hits	291	Target Neighborhood Hits	149	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TAV0, O95565, O95566, Q8N7J5	Gene names	FAM76A
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

FA76A_MOUSE
θ value	0.163984 (rank : 162)	NC score	0.056018 (rank : 469)
Query Neighborhood Hits	291	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	Q922G2, Q3U3U8, Q3V3N2	Gene names	Fam76a
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

LTB1L_HUMAN
θ value	0.163984 (rank : 163)	NC score	0.238958 (rank : 86)
Query Neighborhood Hits	291	Target Neighborhood Hits	553	Shared Neighborhood Hits	179
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	0.163984 (rank : 164)	NC score	0.239082 (rank : 85)
Query Neighborhood Hits	291	Target Neighborhood Hits	502	Shared Neighborhood Hits	176
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DNER_HUMAN
θ value	0.21417 (rank : 165)	NC score	0.224678 (rank : 112)
Query Neighborhood Hits	291	Target Neighborhood Hits	460	Shared Neighborhood Hits	159
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

LYAM2_HUMAN
θ value	0.21417 (rank : 166)	NC score	0.108151 (rank : 323)
Query Neighborhood Hits	291	Target Neighborhood Hits	394	Shared Neighborhood Hits	146
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

NOTC4_HUMAN
θ value	0.21417 (rank : 167)	NC score	0.223267 (rank : 115)
Query Neighborhood Hits	291	Target Neighborhood Hits	905	Shared Neighborhood Hits	189
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TNR6_HUMAN
θ value	0.21417 (rank : 168)	NC score	0.101916 (rank : 335)
Query Neighborhood Hits	291	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

FBLN5_HUMAN
θ value	0.279714 (rank : 169)	NC score	0.225431 (rank : 111)
Query Neighborhood Hits	291	Target Neighborhood Hits	329	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

ITB8_HUMAN
θ value	0.279714 (rank : 170)	NC score	0.156176 (rank : 232)
Query Neighborhood Hits	291	Target Neighborhood Hits	280	Shared Neighborhood Hits	148
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

LTBP3_MOUSE
θ value	0.279714 (rank : 171)	NC score	0.233816 (rank : 99)
Query Neighborhood Hits	291	Target Neighborhood Hits	475	Shared Neighborhood Hits	182
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TR10C_HUMAN
θ value	0.279714 (rank : 172)	NC score	0.094307 (rank : 362)
Query Neighborhood Hits	291	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TRBM_HUMAN
θ value	0.279714 (rank : 173)	NC score	0.224146 (rank : 114)
Query Neighborhood Hits	291	Target Neighborhood Hits	339	Shared Neighborhood Hits	152
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ZN429_HUMAN
θ value	0.279714 (rank : 174)	NC score	-0.004219 (rank : 538)
Query Neighborhood Hits	291	Target Neighborhood Hits	766	Shared Neighborhood Hits	11
SwissProt Accessions	Q86V71	Gene names	ZNF429
Domain Architecture
Description	Zinc finger protein 429.

JAG1_HUMAN
θ value	0.365318 (rank : 175)	NC score	0.244389 (rank : 74)
Query Neighborhood Hits	291	Target Neighborhood Hits	514	Shared Neighborhood Hits	177
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

PAPPA_MOUSE
θ value	0.365318 (rank : 176)	NC score	0.052932 (rank : 484)
Query Neighborhood Hits	291	Target Neighborhood Hits	153	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

ATS19_HUMAN
θ value	0.47712 (rank : 177)	NC score	0.033819 (rank : 517)
Query Neighborhood Hits	291	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

BAI3_MOUSE
θ value	0.47712 (rank : 178)	NC score	0.041580 (rank : 508)
Query Neighborhood Hits	291	Target Neighborhood Hits	250	Shared Neighborhood Hits	40
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

ITB2_MOUSE
θ value	0.47712 (rank : 179)	NC score	0.184237 (rank : 185)
Query Neighborhood Hits	291	Target Neighborhood Hits	326	Shared Neighborhood Hits	157
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB5_HUMAN
θ value	0.47712 (rank : 180)	NC score	0.188255 (rank : 173)
Query Neighborhood Hits	291	Target Neighborhood Hits	310	Shared Neighborhood Hits	164
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

TR10D_HUMAN
θ value	0.47712 (rank : 181)	NC score	0.084166 (rank : 391)
Query Neighborhood Hits	291	Target Neighborhood Hits	62	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

ZN330_HUMAN
θ value	0.47712 (rank : 182)	NC score	0.060782 (rank : 459)
Query Neighborhood Hits	291	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

LDLR_MOUSE
θ value	0.62314 (rank : 183)	NC score	0.165987 (rank : 214)
Query Neighborhood Hits	291	Target Neighborhood Hits	382	Shared Neighborhood Hits	156
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

NOTC3_HUMAN
θ value	0.62314 (rank : 184)	NC score	0.227405 (rank : 108)
Query Neighborhood Hits	291	Target Neighborhood Hits	1062	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

SORL_MOUSE
θ value	0.62314 (rank : 185)	NC score	0.141067 (rank : 259)
Query Neighborhood Hits	291	Target Neighborhood Hits	439	Shared Neighborhood Hits	152
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

THYG_HUMAN
θ value	0.62314 (rank : 186)	NC score	0.046343 (rank : 503)
Query Neighborhood Hits	291	Target Neighborhood Hits	154	Shared Neighborhood Hits	55
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TNR11_HUMAN
θ value	0.62314 (rank : 187)	NC score	0.096569 (rank : 353)
Query Neighborhood Hits	291	Target Neighborhood Hits	135	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

VEGFD_HUMAN
θ value	0.62314 (rank : 188)	NC score	0.022507 (rank : 527)
Query Neighborhood Hits	291	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

BMP1_HUMAN
θ value	0.813845 (rank : 189)	NC score	0.084901 (rank : 390)
Query Neighborhood Hits	291	Target Neighborhood Hits	233	Shared Neighborhood Hits	93
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	0.813845 (rank : 190)	NC score	0.085253 (rank : 388)
Query Neighborhood Hits	291	Target Neighborhood Hits	236	Shared Neighborhood Hits	93
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CILP1_HUMAN
θ value	0.813845 (rank : 191)	NC score	0.039028 (rank : 511)
Query Neighborhood Hits	291	Target Neighborhood Hits	266	Shared Neighborhood Hits	37
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

LAMB3_MOUSE
θ value	0.813845 (rank : 192)	NC score	0.242722 (rank : 77)
Query Neighborhood Hits	291	Target Neighborhood Hits	444	Shared Neighborhood Hits	146
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LTBP4_MOUSE
θ value	0.813845 (rank : 193)	NC score	0.252537 (rank : 68)
Query Neighborhood Hits	291	Target Neighborhood Hits	607	Shared Neighborhood Hits	187
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MBTP1_HUMAN
θ value	0.813845 (rank : 194)	NC score	0.085314 (rank : 387)
Query Neighborhood Hits	291	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

MBTP1_MOUSE
θ value	0.813845 (rank : 195)	NC score	0.080271 (rank : 399)
Query Neighborhood Hits	291	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTZ2, Q6PG67	Gene names	Mbtps1, S1p, Ski1
Domain Architecture
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin isozyme 1) (SKI-1) (Sterol-regulated luminal protease).

SLIT1_MOUSE
θ value	0.813845 (rank : 196)	NC score	0.149510 (rank : 244)
Query Neighborhood Hits	291	Target Neighborhood Hits	715	Shared Neighborhood Hits	164
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SSPO_MOUSE
θ value	0.813845 (rank : 197)	NC score	0.202288 (rank : 149)
Query Neighborhood Hits	291	Target Neighborhood Hits	800	Shared Neighborhood Hits	225
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TENX_HUMAN
θ value	0.813845 (rank : 198)	NC score	0.201222 (rank : 151)
Query Neighborhood Hits	291	Target Neighborhood Hits	789	Shared Neighborhood Hits	183
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TNR5_MOUSE
θ value	0.813845 (rank : 199)	NC score	0.116205 (rank : 298)
Query Neighborhood Hits	291	Target Neighborhood Hits	131	Shared Neighborhood Hits	84
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

CSMD1_MOUSE
θ value	1.06291 (rank : 200)	NC score	0.036433 (rank : 514)
Query Neighborhood Hits	291	Target Neighborhood Hits	193	Shared Neighborhood Hits	43
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

NID2_MOUSE
θ value	1.06291 (rank : 201)	NC score	0.194115 (rank : 159)
Query Neighborhood Hits	291	Target Neighborhood Hits	338	Shared Neighborhood Hits	149
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

TLL2_MOUSE
θ value	1.06291 (rank : 202)	NC score	0.080607 (rank : 397)
Query Neighborhood Hits	291	Target Neighborhood Hits	240	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TNR1A_HUMAN
θ value	1.06291 (rank : 203)	NC score	0.115449 (rank : 301)
Query Neighborhood Hits	291	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR1B_MOUSE
θ value	1.06291 (rank : 204)	NC score	0.109989 (rank : 314)
Query Neighborhood Hits	291	Target Neighborhood Hits	123	Shared Neighborhood Hits	56
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TR10B_HUMAN
θ value	1.06291 (rank : 205)	NC score	0.089743 (rank : 378)
Query Neighborhood Hits	291	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR13B_MOUSE
θ value	1.06291 (rank : 206)	NC score	0.058801 (rank : 461)
Query Neighborhood Hits	291	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ET35, Q9DBZ3	Gene names	Tnfrsf13b, Taci
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor).

BAI3_HUMAN
θ value	1.38821 (rank : 207)	NC score	0.040585 (rank : 509)
Query Neighborhood Hits	291	Target Neighborhood Hits	246	Shared Neighborhood Hits	39
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

EPHA1_HUMAN
θ value	1.38821 (rank : 208)	NC score	0.052394 (rank : 487)
Query Neighborhood Hits	291	Target Neighborhood Hits	997	Shared Neighborhood Hits	96
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

JAG1_MOUSE
θ value	1.38821 (rank : 209)	NC score	0.242407 (rank : 79)
Query Neighborhood Hits	291	Target Neighborhood Hits	518	Shared Neighborhood Hits	176
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

MKS3_HUMAN
θ value	1.38821 (rank : 210)	NC score	0.074184 (rank : 413)
Query Neighborhood Hits	291	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

PARC_HUMAN
θ value	1.38821 (rank : 211)	NC score	0.009853 (rank : 531)
Query Neighborhood Hits	291	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

RNF37_MOUSE
θ value	1.38821 (rank : 212)	NC score	0.020663 (rank : 528)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

THYG_MOUSE
θ value	1.38821 (rank : 213)	NC score	0.042786 (rank : 506)
Query Neighborhood Hits	291	Target Neighborhood Hits	161	Shared Neighborhood Hits	61
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TNR14_HUMAN
θ value	1.38821 (rank : 214)	NC score	0.141433 (rank : 258)
Query Neighborhood Hits	291	Target Neighborhood Hits	149	Shared Neighborhood Hits	94
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR3_MOUSE
θ value	1.38821 (rank : 215)	NC score	0.106308 (rank : 324)
Query Neighborhood Hits	291	Target Neighborhood Hits	113	Shared Neighborhood Hits	72
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TR11B_HUMAN
θ value	1.38821 (rank : 216)	NC score	0.099158 (rank : 346)
Query Neighborhood Hits	291	Target Neighborhood Hits	92	Shared Neighborhood Hits	57
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

MT1H_HUMAN
θ value	1.81305 (rank : 217)	NC score	0.108159 (rank : 322)
Query Neighborhood Hits	291	Target Neighborhood Hits	78	Shared Neighborhood Hits	51
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

NOTC3_MOUSE
θ value	1.81305 (rank : 218)	NC score	0.224301 (rank : 113)
Query Neighborhood Hits	291	Target Neighborhood Hits	975	Shared Neighborhood Hits	189
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TNR16_HUMAN
θ value	1.81305 (rank : 219)	NC score	0.174465 (rank : 199)
Query Neighborhood Hits	291	Target Neighborhood Hits	183	Shared Neighborhood Hits	101
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TSP2_MOUSE
θ value	1.81305 (rank : 220)	NC score	0.141722 (rank : 256)
Query Neighborhood Hits	291	Target Neighborhood Hits	352	Shared Neighborhood Hits	147
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

ZNFX1_MOUSE
θ value	1.81305 (rank : 221)	NC score	0.109915 (rank : 315)
Query Neighborhood Hits	291	Target Neighborhood Hits	407	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ATRN_MOUSE
θ value	2.36792 (rank : 222)	NC score	0.188159 (rank : 175)
Query Neighborhood Hits	291	Target Neighborhood Hits	519	Shared Neighborhood Hits	158
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

EMR1_HUMAN
θ value	2.36792 (rank : 223)	NC score	0.165043 (rank : 216)
Query Neighborhood Hits	291	Target Neighborhood Hits	382	Shared Neighborhood Hits	145
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EPHA7_HUMAN
θ value	2.36792 (rank : 224)	NC score	0.050796 (rank : 493)
Query Neighborhood Hits	291	Target Neighborhood Hits	1053	Shared Neighborhood Hits	105
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

FAM5C_HUMAN
θ value	2.36792 (rank : 225)	NC score	0.023404 (rank : 526)
Query Neighborhood Hits	291	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q76B58, O95726	Gene names	FAM5C, DBCCR1L, DBCCR1L1
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor (DBCCR1-like protein 1).

FAM5C_MOUSE
θ value	2.36792 (rank : 226)	NC score	0.023449 (rank : 525)
Query Neighborhood Hits	291	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q499E0, Q8K0R9	Gene names	Fam5c
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor.

FBLN3_HUMAN
θ value	2.36792 (rank : 227)	NC score	0.207976 (rank : 144)
Query Neighborhood Hits	291	Target Neighborhood Hits	293	Shared Neighborhood Hits	150
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	2.36792 (rank : 228)	NC score	0.199713 (rank : 152)
Query Neighborhood Hits	291	Target Neighborhood Hits	279	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

KR511_HUMAN
θ value	2.36792 (rank : 229)	NC score	0.226277 (rank : 109)
Query Neighborhood Hits	291	Target Neighborhood Hits	231	Shared Neighborhood Hits	104
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA59_HUMAN
θ value	2.36792 (rank : 230)	NC score	0.299660 (rank : 34)
Query Neighborhood Hits	291	Target Neighborhood Hits	310	Shared Neighborhood Hits	135
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

MT2_MOUSE
θ value	2.36792 (rank : 231)	NC score	0.128035 (rank : 277)
Query Neighborhood Hits	291	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

WIF1_HUMAN
θ value	2.36792 (rank : 232)	NC score	0.216513 (rank : 125)
Query Neighborhood Hits	291	Target Neighborhood Hits	392	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ATS16_HUMAN
θ value	3.0926 (rank : 233)	NC score	0.030181 (rank : 520)
Query Neighborhood Hits	291	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

EPHA2_MOUSE
θ value	3.0926 (rank : 234)	NC score	0.052640 (rank : 486)
Query Neighborhood Hits	291	Target Neighborhood Hits	1020	Shared Neighborhood Hits	94
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

KRA51_HUMAN
θ value	3.0926 (rank : 235)	NC score	0.314954 (rank : 26)
Query Neighborhood Hits	291	Target Neighborhood Hits	288	Shared Neighborhood Hits	136
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

MT1A_HUMAN
θ value	3.0926 (rank : 236)	NC score	0.113832 (rank : 305)
Query Neighborhood Hits	291	Target Neighborhood Hits	74	Shared Neighborhood Hits	46
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1G_HUMAN
θ value	3.0926 (rank : 237)	NC score	0.099898 (rank : 343)
Query Neighborhood Hits	291	Target Neighborhood Hits	63	Shared Neighborhood Hits	40
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT1I_HUMAN
θ value	3.0926 (rank : 238)	NC score	0.076380 (rank : 404)
Query Neighborhood Hits	291	Target Neighborhood Hits	64	Shared Neighborhood Hits	42
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

MT1L_HUMAN
θ value	3.0926 (rank : 239)	NC score	0.108997 (rank : 319)
Query Neighborhood Hits	291	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

PHF7_HUMAN
θ value	3.0926 (rank : 240)	NC score	0.027167 (rank : 522)
Query Neighborhood Hits	291	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

SLIT3_MOUSE
θ value	3.0926 (rank : 241)	NC score	0.139883 (rank : 261)
Query Neighborhood Hits	291	Target Neighborhood Hits	700	Shared Neighborhood Hits	163
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

C1QR1_MOUSE
θ value	4.03905 (rank : 242)	NC score	0.211372 (rank : 137)
Query Neighborhood Hits	291	Target Neighborhood Hits	342	Shared Neighborhood Hits	156
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

COLQ_HUMAN
θ value	4.03905 (rank : 243)	NC score	0.004561 (rank : 533)
Query Neighborhood Hits	291	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

DLK_MOUSE
θ value	4.03905 (rank : 244)	NC score	0.214294 (rank : 134)
Query Neighborhood Hits	291	Target Neighborhood Hits	374	Shared Neighborhood Hits	158
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

LDLR_HUMAN
θ value	4.03905 (rank : 245)	NC score	0.172016 (rank : 202)
Query Neighborhood Hits	291	Target Neighborhood Hits	375	Shared Neighborhood Hits	159
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MT1E_HUMAN
θ value	4.03905 (rank : 246)	NC score	0.086573 (rank : 384)
Query Neighborhood Hits	291	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT1F_HUMAN
θ value	4.03905 (rank : 247)	NC score	0.086693 (rank : 383)
Query Neighborhood Hits	291	Target Neighborhood Hits	73	Shared Neighborhood Hits	45
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT2_HUMAN
θ value	4.03905 (rank : 248)	NC score	0.085827 (rank : 386)
Query Neighborhood Hits	291	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

PCSK9_HUMAN
θ value	4.03905 (rank : 249)	NC score	0.055223 (rank : 474)
Query Neighborhood Hits	291	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBP7, Q5PSM5	Gene names	PCSK9, NARC1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

ZN208_HUMAN
θ value	4.03905 (rank : 250)	NC score	-0.004708 (rank : 539)
Query Neighborhood Hits	291	Target Neighborhood Hits	771	Shared Neighborhood Hits	13
SwissProt Accessions	O43345	Gene names	ZNF208, ZNF91L
Domain Architecture
Description	Zinc finger protein 208.

ADA22_HUMAN
θ value	5.27518 (rank : 251)	NC score	0.035286 (rank : 515)
Query Neighborhood Hits	291	Target Neighborhood Hits	211	Shared Neighborhood Hits	96
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

CSMD1_HUMAN
θ value	5.27518 (rank : 252)	NC score	0.033064 (rank : 518)
Query Neighborhood Hits	291	Target Neighborhood Hits	176	Shared Neighborhood Hits	34
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

DLL3_MOUSE
θ value	5.27518 (rank : 253)	NC score	0.215680 (rank : 128)
Query Neighborhood Hits	291	Target Neighborhood Hits	399	Shared Neighborhood Hits	162
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

FAM5B_MOUSE
θ value	5.27518 (rank : 254)	NC score	0.030982 (rank : 519)
Query Neighborhood Hits	291	Target Neighborhood Hits	51	Shared Neighborhood Hits	27
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

LTBP3_HUMAN
θ value	5.27518 (rank : 255)	NC score	0.229169 (rank : 107)
Query Neighborhood Hits	291	Target Neighborhood Hits	502	Shared Neighborhood Hits	179
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NOTC2_HUMAN
θ value	5.27518 (rank : 256)	NC score	0.219395 (rank : 119)
Query Neighborhood Hits	291	Target Neighborhood Hits	1113	Shared Neighborhood Hits	193
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SLIT1_HUMAN
θ value	5.27518 (rank : 257)	NC score	0.148485 (rank : 246)
Query Neighborhood Hits	291	Target Neighborhood Hits	700	Shared Neighborhood Hits	163
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT3_HUMAN
θ value	5.27518 (rank : 258)	NC score	0.139828 (rank : 262)
Query Neighborhood Hits	291	Target Neighborhood Hits	682	Shared Neighborhood Hits	161
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

TNR7_HUMAN
θ value	5.27518 (rank : 259)	NC score	0.133679 (rank : 273)
Query Neighborhood Hits	291	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR7_MOUSE
θ value	5.27518 (rank : 260)	NC score	0.104832 (rank : 329)
Query Neighborhood Hits	291	Target Neighborhood Hits	112	Shared Neighborhood Hits	68
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

V2R1B_MOUSE
θ value	5.27518 (rank : 261)	NC score	0.005943 (rank : 532)
Query Neighborhood Hits	291	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

ZN611_HUMAN
θ value	5.27518 (rank : 262)	NC score	-0.003126 (rank : 537)
Query Neighborhood Hits	291	Target Neighborhood Hits	769	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N823, Q69YG9	Gene names	ZNF611
Domain Architecture	No domain graphic available
Description	Zinc finger protein 611.

1A25_HUMAN
θ value	6.88961 (rank : 263)	NC score	-0.002504 (rank : 536)
Query Neighborhood Hits	291	Target Neighborhood Hits	202	Shared Neighborhood Hits	3
SwissProt Accessions	P18462, Q95362, Q9TQE8, Q9TQG0, Q9UQU3	Gene names	HLA-A, HLAA
Domain Architecture
Description	HLA class I histocompatibility antigen, A-25 alpha chain precursor (MHC class I antigen A*25) (A-10).

ADA22_MOUSE
θ value	6.88961 (rank : 264)	NC score	0.038796 (rank : 512)
Query Neighborhood Hits	291	Target Neighborhood Hits	225	Shared Neighborhood Hits	95
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ATRN_HUMAN
θ value	6.88961 (rank : 265)	NC score	0.179147 (rank : 192)
Query Neighborhood Hits	291	Target Neighborhood Hits	525	Shared Neighborhood Hits	153
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATS18_MOUSE
θ value	6.88961 (rank : 266)	NC score	0.024115 (rank : 524)
Query Neighborhood Hits	291	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

CD97_HUMAN
θ value	6.88961 (rank : 267)	NC score	0.151496 (rank : 239)
Query Neighborhood Hits	291	Target Neighborhood Hits	353	Shared Neighborhood Hits	136
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CRUM2_HUMAN
θ value	6.88961 (rank : 268)	NC score	0.215462 (rank : 131)
Query Neighborhood Hits	291	Target Neighborhood Hits	453	Shared Neighborhood Hits	171
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

EGF_MOUSE
θ value	6.88961 (rank : 269)	NC score	0.189330 (rank : 169)
Query Neighborhood Hits	291	Target Neighborhood Hits	358	Shared Neighborhood Hits	160
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

EPHA4_MOUSE
θ value	6.88961 (rank : 270)	NC score	0.043057 (rank : 505)
Query Neighborhood Hits	291	Target Neighborhood Hits	982	Shared Neighborhood Hits	63
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

FBXL2_MOUSE
θ value	6.88961 (rank : 271)	NC score	0.002387 (rank : 534)
Query Neighborhood Hits	291	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

FHR4_HUMAN
θ value	6.88961 (rank : 272)	NC score	0.014101 (rank : 530)
Query Neighborhood Hits	291	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

KRA55_HUMAN
θ value	6.88961 (rank : 273)	NC score	0.292865 (rank : 36)
Query Neighborhood Hits	291	Target Neighborhood Hits	257	Shared Neighborhood Hits	120
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

LYAM3_MOUSE
θ value	6.88961 (rank : 274)	NC score	0.116524 (rank : 297)
Query Neighborhood Hits	291	Target Neighborhood Hits	390	Shared Neighborhood Hits	142
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TNR23_MOUSE
θ value	6.88961 (rank : 275)	NC score	0.147510 (rank : 248)
Query Neighborhood Hits	291	Target Neighborhood Hits	114	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TR13B_HUMAN
θ value	6.88961 (rank : 276)	NC score	0.049940 (rank : 502)
Query Neighborhood Hits	291	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	O14836, Q7Z6F5	Gene names	TNFRSF13B, TACI
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD267 antigen).

ZAN_HUMAN
θ value	6.88961 (rank : 277)	NC score	0.130379 (rank : 275)
Query Neighborhood Hits	291	Target Neighborhood Hits	679	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

ADA17_HUMAN
θ value	8.99809 (rank : 278)	NC score	0.051604 (rank : 491)
Query Neighborhood Hits	291	Target Neighborhood Hits	223	Shared Neighborhood Hits	87
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ATS18_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.026815 (rank : 523)
Query Neighborhood Hits	291	Target Neighborhood Hits	169	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

C1R_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.035112 (rank : 516)
Query Neighborhood Hits	291	Target Neighborhood Hits	364	Shared Neighborhood Hits	85
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

EPHA4_HUMAN
θ value	8.99809 (rank : 281)	NC score	0.041905 (rank : 507)
Query Neighborhood Hits	291	Target Neighborhood Hits	975	Shared Neighborhood Hits	59
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHA8_MOUSE
θ value	8.99809 (rank : 282)	NC score	0.039991 (rank : 510)
Query Neighborhood Hits	291	Target Neighborhood Hits	969	Shared Neighborhood Hits	46
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

FA10_MOUSE
θ value	8.99809 (rank : 283)	NC score	0.057573 (rank : 464)
Query Neighborhood Hits	291	Target Neighborhood Hits	435	Shared Neighborhood Hits	130
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FAM5B_HUMAN
θ value	8.99809 (rank : 284)	NC score	0.027542 (rank : 521)
Query Neighborhood Hits	291	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

HFE_HUMAN
θ value	8.99809 (rank : 285)	NC score	-0.002312 (rank : 535)
Query Neighborhood Hits	291	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q30201, O75929, O75930, O75931, Q96KU5, Q96KU7, Q96KU8, Q9HC64, Q9HC68, Q9HC70, Q9HC83	Gene names	HFE, HLAH
Domain Architecture
Description	Hereditary hemochromatosis protein precursor (HLA-H).

ITB5_MOUSE
θ value	8.99809 (rank : 286)	NC score	0.191337 (rank : 164)
Query Neighborhood Hits	291	Target Neighborhood Hits	329	Shared Neighborhood Hits	171
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

MKS3_MOUSE
θ value	8.99809 (rank : 287)	NC score	0.092310 (rank : 372)
Query Neighborhood Hits	291	Target Neighborhood Hits	89	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MT1X_HUMAN
θ value	8.99809 (rank : 288)	NC score	0.111601 (rank : 311)
Query Neighborhood Hits	291	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

NET2_MOUSE
θ value	8.99809 (rank : 289)	NC score	0.190103 (rank : 167)
Query Neighborhood Hits	291	Target Neighborhood Hits	193	Shared Neighborhood Hits	110
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

TMPS7_MOUSE
θ value	8.99809 (rank : 290)	NC score	0.016679 (rank : 529)
Query Neighborhood Hits	291	Target Neighborhood Hits	275	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

ZN679_HUMAN
θ value	8.99809 (rank : 291)	NC score	-0.005726 (rank : 540)
Query Neighborhood Hits	291	Target Neighborhood Hits	746	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYX0	Gene names	ZNF679
Domain Architecture	No domain graphic available
Description	Zinc finger protein 679.

ADA19_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.050410 (rank : 499)
Query Neighborhood Hits	291	Target Neighborhood Hits	315	Shared Neighborhood Hits	118
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ASTN_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.052774 (rank : 485)
Query Neighborhood Hits	291	Target Neighborhood Hits	105	Shared Neighborhood Hits	54
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.050580 (rank : 496)
Query Neighborhood Hits	291	Target Neighborhood Hits	98	Shared Neighborhood Hits	52
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

BMPER_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.159084 (rank : 226)
Query Neighborhood Hits	291	Target Neighborhood Hits	175	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CD248_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.157108 (rank : 228)
Query Neighborhood Hits	291	Target Neighborhood Hits	679	Shared Neighborhood Hits	132
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.156610 (rank : 229)
Query Neighborhood Hits	291	Target Neighborhood Hits	578	Shared Neighborhood Hits	128
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.120964 (rank : 290)
Query Neighborhood Hits	291	Target Neighborhood Hits	295	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CELR1_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.092620 (rank : 370)
Query Neighborhood Hits	291	Target Neighborhood Hits	613	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.093894 (rank : 365)
Query Neighborhood Hits	291	Target Neighborhood Hits	617	Shared Neighborhood Hits	167
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.098500 (rank : 348)
Query Neighborhood Hits	291	Target Neighborhood Hits	657	Shared Neighborhood Hits	170
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR2_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.090387 (rank : 376)
Query Neighborhood Hits	291	Target Neighborhood Hits	584	Shared Neighborhood Hits	157
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR3_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.093963 (rank : 363)
Query Neighborhood Hits	291	Target Neighborhood Hits	680	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
θ value	θ > 10 (rank : 304)	NC score	0.093937 (rank : 364)
Query Neighborhood Hits	291	Target Neighborhood Hits	687	Shared Neighborhood Hits	162
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CFC1_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.097845 (rank : 349)
Query Neighborhood Hits	291	Target Neighborhood Hits	148	Shared Neighborhood Hits	80
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.074504 (rank : 411)
Query Neighborhood Hits	291	Target Neighborhood Hits	125	Shared Neighborhood Hits	67
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CHRD_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.091187 (rank : 374)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.089520 (rank : 379)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CLC14_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.062408 (rank : 453)
Query Neighborhood Hits	291	Target Neighborhood Hits	143	Shared Neighborhood Hits	68
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.066805 (rank : 436)
Query Neighborhood Hits	291	Target Neighborhood Hits	120	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CO6_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.061032 (rank : 458)
Query Neighborhood Hits	291	Target Neighborhood Hits	331	Shared Neighborhood Hits	107
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.176570 (rank : 195)
Query Neighborhood Hits	291	Target Neighborhood Hits	258	Shared Neighborhood Hits	141
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.176283 (rank : 196)
Query Neighborhood Hits	291	Target Neighborhood Hits	290	Shared Neighborhood Hits	152
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CORIN_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.054945 (rank : 477)
Query Neighborhood Hits	291	Target Neighborhood Hits	453	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.050320 (rank : 500)
Query Neighborhood Hits	291	Target Neighborhood Hits	451	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CRAC1_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.093475 (rank : 366)
Query Neighborhood Hits	291	Target Neighborhood Hits	111	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.094904 (rank : 358)
Query Neighborhood Hits	291	Target Neighborhood Hits	112	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRDL1_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.063251 (rank : 446)
Query Neighborhood Hits	291	Target Neighborhood Hits	75	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.063104 (rank : 448)
Query Neighborhood Hits	291	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.067877 (rank : 433)
Query Neighborhood Hits	291	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.070578 (rank : 427)
Query Neighborhood Hits	291	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CRUM1_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.218423 (rank : 121)
Query Neighborhood Hits	291	Target Neighborhood Hits	457	Shared Neighborhood Hits	167
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.217990 (rank : 123)
Query Neighborhood Hits	291	Target Neighborhood Hits	444	Shared Neighborhood Hits	169
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CSPG2_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.097420 (rank : 352)
Query Neighborhood Hits	291	Target Neighborhood Hits	681	Shared Neighborhood Hits	138
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.099455 (rank : 344)
Query Neighborhood Hits	291	Target Neighborhood Hits	711	Shared Neighborhood Hits	140
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.095453 (rank : 357)
Query Neighborhood Hits	291	Target Neighborhood Hits	676	Shared Neighborhood Hits	140
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 327)	NC score	0.100619 (rank : 340)
Query Neighborhood Hits	291	Target Neighborhood Hits	657	Shared Neighborhood Hits	142
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG4_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.064786 (rank : 440)
Query Neighborhood Hits	291	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.061133 (rank : 457)
Query Neighborhood Hits	291	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CT127_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.105148 (rank : 328)
Query Neighborhood Hits	291	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

DLK_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.215976 (rank : 126)
Query Neighborhood Hits	291	Target Neighborhood Hits	401	Shared Neighborhood Hits	169
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DNER_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.218207 (rank : 122)
Query Neighborhood Hits	291	Target Neighborhood Hits	413	Shared Neighborhood Hits	156
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.120867 (rank : 291)
Query Neighborhood Hits	291	Target Neighborhood Hits	292	Shared Neighborhood Hits	128
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.125978 (rank : 282)
Query Neighborhood Hits	291	Target Neighborhood Hits	317	Shared Neighborhood Hits	136
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.172033 (rank : 201)
Query Neighborhood Hits	291	Target Neighborhood Hits	325	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.161687 (rank : 221)
Query Neighborhood Hits	291	Target Neighborhood Hits	287	Shared Neighborhood Hits	130
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.151108 (rank : 242)
Query Neighborhood Hits	291	Target Neighborhood Hits	270	Shared Neighborhood Hits	116
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 338)	NC score	0.147986 (rank : 247)
Query Neighborhood Hits	291	Target Neighborhood Hits	266	Shared Neighborhood Hits	120
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.214912 (rank : 133)
Query Neighborhood Hits	291	Target Neighborhood Hits	365	Shared Neighborhood Hits	162
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 340)	NC score	0.213245 (rank : 136)
Query Neighborhood Hits	291	Target Neighborhood Hits	379	Shared Neighborhood Hits	161
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.186163 (rank : 178)
Query Neighborhood Hits	291	Target Neighborhood Hits	343	Shared Neighborhood Hits	156
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

ELTD1_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.081646 (rank : 394)
Query Neighborhood Hits	291	Target Neighborhood Hits	269	Shared Neighborhood Hits	106
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.114637 (rank : 304)
Query Neighborhood Hits	291	Target Neighborhood Hits	288	Shared Neighborhood Hits	114
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.151324 (rank : 240)
Query Neighborhood Hits	291	Target Neighborhood Hits	349	Shared Neighborhood Hits	134
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.152054 (rank : 238)
Query Neighborhood Hits	291	Target Neighborhood Hits	345	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.058833 (rank : 460)
Query Neighborhood Hits	291	Target Neighborhood Hits	245	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EPHA1_MOUSE
θ value	θ > 10 (rank : 347)	NC score	0.051077 (rank : 492)
Query Neighborhood Hits	291	Target Neighborhood Hits	958	Shared Neighborhood Hits	91
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHAA_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.051706 (rank : 490)
Query Neighborhood Hits	291	Target Neighborhood Hits	960	Shared Neighborhood Hits	65
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

EPHB4_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.055713 (rank : 471)
Query Neighborhood Hits	291	Target Neighborhood Hits	1056	Shared Neighborhood Hits	129
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB6_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.051752 (rank : 489)
Query Neighborhood Hits	291	Target Neighborhood Hits	912	Shared Neighborhood Hits	85
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

ESM1_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.089807 (rank : 377)
Query Neighborhood Hits	291	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.082772 (rank : 392)
Query Neighborhood Hits	291	Target Neighborhood Hits	107	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FA10_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.054994 (rank : 476)
Query Neighborhood Hits	291	Target Neighborhood Hits	431	Shared Neighborhood Hits	127
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.050553 (rank : 497)
Query Neighborhood Hits	291	Target Neighborhood Hits	421	Shared Neighborhood Hits	118
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FATH_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.094365 (rank : 360)
Query Neighborhood Hits	291	Target Neighborhood Hits	570	Shared Neighborhood Hits	156
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FREM1_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.056565 (rank : 466)
Query Neighborhood Hits	291	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM1_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.055022 (rank : 475)
Query Neighborhood Hits	291	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM2_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.071310 (rank : 425)
Query Neighborhood Hits	291	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM2_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.071792 (rank : 423)
Query Neighborhood Hits	291	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

FREM3_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.062830 (rank : 450)
Query Neighborhood Hits	291	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM3_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.062863 (rank : 449)
Query Neighborhood Hits	291	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

FSTL3_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.056923 (rank : 465)
Query Neighborhood Hits	291	Target Neighborhood Hits	162	Shared Neighborhood Hits	70
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.062448 (rank : 452)
Query Neighborhood Hits	291	Target Neighborhood Hits	129	Shared Neighborhood Hits	44
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.068975 (rank : 431)
Query Neighborhood Hits	291	Target Neighborhood Hits	146	Shared Neighborhood Hits	53
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GAS6_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.186089 (rank : 179)
Query Neighborhood Hits	291	Target Neighborhood Hits	348	Shared Neighborhood Hits	153
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.184482 (rank : 184)
Query Neighborhood Hits	291	Target Neighborhood Hits	343	Shared Neighborhood Hits	153
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GRN_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.169931 (rank : 206)
Query Neighborhood Hits	291	Target Neighborhood Hits	268	Shared Neighborhood Hits	123
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.169267 (rank : 209)
Query Neighborhood Hits	291	Target Neighborhood Hits	248	Shared Neighborhood Hits	121
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HABP2_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.062822 (rank : 451)
Query Neighborhood Hits	291	Target Neighborhood Hits	431	Shared Neighborhood Hits	127
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.062052 (rank : 454)
Query Neighborhood Hits	291	Target Neighborhood Hits	445	Shared Neighborhood Hits	127
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HHIP_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.138571 (rank : 264)
Query Neighborhood Hits	291	Target Neighborhood Hits	249	Shared Neighborhood Hits	117
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.136318 (rank : 270)
Query Neighborhood Hits	291	Target Neighborhood Hits	219	Shared Neighborhood Hits	108
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB2_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.171441 (rank : 204)
Query Neighborhood Hits	291	Target Neighborhood Hits	282	Shared Neighborhood Hits	152
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB4_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.156557 (rank : 230)
Query Neighborhood Hits	291	Target Neighborhood Hits	458	Shared Neighborhood Hits	150
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB6_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.169891 (rank : 207)
Query Neighborhood Hits	291	Target Neighborhood Hits	318	Shared Neighborhood Hits	155
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.178798 (rank : 193)
Query Neighborhood Hits	291	Target Neighborhood Hits	341	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

KR101_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.179295 (rank : 191)
Query Neighborhood Hits	291	Target Neighborhood Hits	261	Shared Neighborhood Hits	120
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.144938 (rank : 253)
Query Neighborhood Hits	291	Target Neighborhood Hits	264	Shared Neighborhood Hits	115
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.103208 (rank : 331)
Query Neighborhood Hits	291	Target Neighborhood Hits	212	Shared Neighborhood Hits	85
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR104_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.215626 (rank : 130)
Query Neighborhood Hits	291	Target Neighborhood Hits	313	Shared Neighborhood Hits	140
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.153851 (rank : 235)
Query Neighborhood Hits	291	Target Neighborhood Hits	271	Shared Neighborhood Hits	111
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.210579 (rank : 139)
Query Neighborhood Hits	291	Target Neighborhood Hits	347	Shared Neighborhood Hits	154
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.211259 (rank : 138)
Query Neighborhood Hits	291	Target Neighborhood Hits	330	Shared Neighborhood Hits	146
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.162555 (rank : 218)
Query Neighborhood Hits	291	Target Neighborhood Hits	226	Shared Neighborhood Hits	102
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.144237 (rank : 254)
Query Neighborhood Hits	291	Target Neighborhood Hits	226	Shared Neighborhood Hits	97
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.101435 (rank : 336)
Query Neighborhood Hits	291	Target Neighborhood Hits	232	Shared Neighborhood Hits	106
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.156443 (rank : 231)
Query Neighborhood Hits	291	Target Neighborhood Hits	269	Shared Neighborhood Hits	115
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.127855 (rank : 278)
Query Neighborhood Hits	291	Target Neighborhood Hits	219	Shared Neighborhood Hits	102
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.188194 (rank : 174)
Query Neighborhood Hits	291	Target Neighborhood Hits	144	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR410_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.090613 (rank : 375)
Query Neighborhood Hits	291	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.120827 (rank : 292)
Query Neighborhood Hits	291	Target Neighborhood Hits	178	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR413_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.061747 (rank : 455)
Query Neighborhood Hits	291	Target Neighborhood Hits	112	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KR414_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.109208 (rank : 318)
Query Neighborhood Hits	291	Target Neighborhood Hits	199	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.251106 (rank : 71)
Query Neighborhood Hits	291	Target Neighborhood Hits	217	Shared Neighborhood Hits	96
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA11_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.125569 (rank : 283)
Query Neighborhood Hits	291	Target Neighborhood Hits	155	Shared Neighborhood Hits	63
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.127749 (rank : 279)
Query Neighborhood Hits	291	Target Neighborhood Hits	144	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.106271 (rank : 325)
Query Neighborhood Hits	291	Target Neighborhood Hits	126	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA24_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.050516 (rank : 498)
Query Neighborhood Hits	291	Target Neighborhood Hits	192	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

KRA42_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.073548 (rank : 418)
Query Neighborhood Hits	291	Target Neighborhood Hits	149	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.124786 (rank : 285)
Query Neighborhood Hits	291	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.155451 (rank : 233)
Query Neighborhood Hits	291	Target Neighborhood Hits	194	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.148797 (rank : 245)
Query Neighborhood Hits	291	Target Neighborhood Hits	204	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA52_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.260415 (rank : 56)
Query Neighborhood Hits	291	Target Neighborhood Hits	236	Shared Neighborhood Hits	112
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA54_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.278825 (rank : 38)
Query Neighborhood Hits	291	Target Neighborhood Hits	270	Shared Neighborhood Hits	122
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA56_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.237645 (rank : 90)
Query Neighborhood Hits	291	Target Neighborhood Hits	207	Shared Neighborhood Hits	105
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.242476 (rank : 78)
Query Neighborhood Hits	291	Target Neighborhood Hits	269	Shared Neighborhood Hits	121
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.268123 (rank : 50)
Query Neighborhood Hits	291	Target Neighborhood Hits	324	Shared Neighborhood Hits	140
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA92_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.147228 (rank : 250)
Query Neighborhood Hits	291	Target Neighborhood Hits	198	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.153368 (rank : 236)
Query Neighborhood Hits	291	Target Neighborhood Hits	203	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.130585 (rank : 274)
Query Neighborhood Hits	291	Target Neighborhood Hits	204	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.147468 (rank : 249)
Query Neighborhood Hits	291	Target Neighborhood Hits	185	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.124469 (rank : 286)
Query Neighborhood Hits	291	Target Neighborhood Hits	173	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA4_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.196597 (rank : 156)
Query Neighborhood Hits	291	Target Neighborhood Hits	708	Shared Neighborhood Hits	141
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.207647 (rank : 146)
Query Neighborhood Hits	291	Target Neighborhood Hits	584	Shared Neighborhood Hits	150
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LCE1A_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.100051 (rank : 342)
Query Neighborhood Hits	291	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.127264 (rank : 280)
Query Neighborhood Hits	291	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.136395 (rank : 269)
Query Neighborhood Hits	291	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.099031 (rank : 347)
Query Neighborhood Hits	291	Target Neighborhood Hits	44	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.113013 (rank : 306)
Query Neighborhood Hits	291	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.115905 (rank : 299)
Query Neighborhood Hits	291	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.127170 (rank : 281)
Query Neighborhood Hits	291	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.121942 (rank : 288)
Query Neighborhood Hits	291	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.115303 (rank : 302)
Query Neighborhood Hits	291	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.118917 (rank : 294)
Query Neighborhood Hits	291	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 425)	NC score	0.095770 (rank : 355)
Query Neighborhood Hits	291	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE4A_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.061639 (rank : 456)
Query Neighborhood Hits	291	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.101063 (rank : 338)
Query Neighborhood Hits	291	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LORI_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.067689 (rank : 434)
Query Neighborhood Hits	291	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRP10_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.064000 (rank : 444)
Query Neighborhood Hits	291	Target Neighborhood Hits	197	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.065764 (rank : 438)
Query Neighborhood Hits	291	Target Neighborhood Hits	169	Shared Neighborhood Hits	65
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.050785 (rank : 494)
Query Neighborhood Hits	291	Target Neighborhood Hits	205	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP3_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.067478 (rank : 435)
Query Neighborhood Hits	291	Target Neighborhood Hits	280	Shared Neighborhood Hits	80
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP4_HUMAN
θ value	θ > 10 (rank : 433)	NC score	0.154199 (rank : 234)
Query Neighborhood Hits	291	Target Neighborhood Hits	355	Shared Neighborhood Hits	147
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 434)	NC score	0.151311 (rank : 241)
Query Neighborhood Hits	291	Target Neighborhood Hits	351	Shared Neighborhood Hits	145
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.069465 (rank : 430)
Query Neighborhood Hits	291	Target Neighborhood Hits	224	Shared Neighborhood Hits	84
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 436)	NC score	0.071636 (rank : 424)
Query Neighborhood Hits	291	Target Neighborhood Hits	236	Shared Neighborhood Hits	89
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 437)	NC score	0.076337 (rank : 405)
Query Neighborhood Hits	291	Target Neighborhood Hits	235	Shared Neighborhood Hits	93
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 438)	NC score	0.074440 (rank : 412)
Query Neighborhood Hits	291	Target Neighborhood Hits	232	Shared Neighborhood Hits	91
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.151039 (rank : 243)
Query Neighborhood Hits	291	Target Neighborhood Hits	346	Shared Neighborhood Hits	138
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.162213 (rank : 219)
Query Neighborhood Hits	291	Target Neighborhood Hits	385	Shared Neighborhood Hits	155
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LYAM1_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.068585 (rank : 432)
Query Neighborhood Hits	291	Target Neighborhood Hits	315	Shared Neighborhood Hits	113
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.074719 (rank : 410)
Query Neighborhood Hits	291	Target Neighborhood Hits	332	Shared Neighborhood Hits	114
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.114893 (rank : 303)
Query Neighborhood Hits	291	Target Neighborhood Hits	420	Shared Neighborhood Hits	156
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.102207 (rank : 334)
Query Neighborhood Hits	291	Target Neighborhood Hits	378	Shared Neighborhood Hits	141
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MATN1_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.085041 (rank : 389)
Query Neighborhood Hits	291	Target Neighborhood Hits	191	Shared Neighborhood Hits	78
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 446)	NC score	0.085890 (rank : 385)
Query Neighborhood Hits	291	Target Neighborhood Hits	186	Shared Neighborhood Hits	74
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN3_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.183250 (rank : 188)
Query Neighborhood Hits	291	Target Neighborhood Hits	261	Shared Neighborhood Hits	128
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.182790 (rank : 189)
Query Neighborhood Hits	291	Target Neighborhood Hits	287	Shared Neighborhood Hits	133
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MCSP_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.065843 (rank : 437)
Query Neighborhood Hits	291	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MFGM_MOUSE
θ value	θ > 10 (rank : 450)	NC score	0.081361 (rank : 395)
Query Neighborhood Hits	291	Target Neighborhood Hits	233	Shared Neighborhood Hits	102
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MT1B_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.093253 (rank : 367)
Query Neighborhood Hits	291	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1M_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.055433 (rank : 472)
Query Neighborhood Hits	291	Target Neighborhood Hits	72	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

MT1_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.109694 (rank : 316)
Query Neighborhood Hits	291	Target Neighborhood Hits	72	Shared Neighborhood Hits	46
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT3_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.145279 (rank : 252)
Query Neighborhood Hits	291	Target Neighborhood Hits	82	Shared Neighborhood Hits	53
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.168868 (rank : 210)
Query Neighborhood Hits	291	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.112677 (rank : 309)
Query Neighborhood Hits	291	Target Neighborhood Hits	83	Shared Neighborhood Hits	54
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MT4_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.124189 (rank : 287)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	67
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC13_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.075621 (rank : 408)
Query Neighborhood Hits	291	Target Neighborhood Hits	447	Shared Neighborhood Hits	104
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC2_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.103520 (rank : 330)
Query Neighborhood Hits	291	Target Neighborhood Hits	906	Shared Neighborhood Hits	120
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.145557 (rank : 251)
Query Neighborhood Hits	291	Target Neighborhood Hits	1020	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NAGPA_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.192268 (rank : 161)
Query Neighborhood Hits	291	Target Neighborhood Hits	282	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.182323 (rank : 190)
Query Neighborhood Hits	291	Target Neighborhood Hits	308	Shared Neighborhood Hits	138
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NET1_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.170902 (rank : 205)
Query Neighborhood Hits	291	Target Neighborhood Hits	149	Shared Neighborhood Hits	90
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.168471 (rank : 211)
Query Neighborhood Hits	291	Target Neighborhood Hits	151	Shared Neighborhood Hits	88
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET2_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.192572 (rank : 160)
Query Neighborhood Hits	291	Target Neighborhood Hits	194	Shared Neighborhood Hits	106
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET4_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.186067 (rank : 180)
Query Neighborhood Hits	291	Target Neighborhood Hits	191	Shared Neighborhood Hits	108
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.187653 (rank : 176)
Query Neighborhood Hits	291	Target Neighborhood Hits	180	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NFX1_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.134635 (rank : 272)
Query Neighborhood Hits	291	Target Neighborhood Hits	405	Shared Neighborhood Hits	109
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.190099 (rank : 168)
Query Neighborhood Hits	291	Target Neighborhood Hits	329	Shared Neighborhood Hits	148
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.191110 (rank : 165)
Query Neighborhood Hits	291	Target Neighborhood Hits	335	Shared Neighborhood Hits	146
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NRX1A_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.058327 (rank : 462)
Query Neighborhood Hits	291	Target Neighborhood Hits	170	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.057698 (rank : 463)
Query Neighborhood Hits	291	Target Neighborhood Hits	164	Shared Neighborhood Hits	63
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.053144 (rank : 483)
Query Neighborhood Hits	291	Target Neighborhood Hits	614	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.055410 (rank : 473)
Query Neighborhood Hits	291	Target Neighborhood Hits	164	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NTNG2_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.215789 (rank : 127)
Query Neighborhood Hits	291	Target Neighborhood Hits	276	Shared Neighborhood Hits	135
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.208808 (rank : 141)
Query Neighborhood Hits	291	Target Neighborhood Hits	276	Shared Neighborhood Hits	138
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PAPPA_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.051841 (rank : 488)
Query Neighborhood Hits	291	Target Neighborhood Hits	161	Shared Neighborhood Hits	51
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PERT_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.075309 (rank : 409)
Query Neighborhood Hits	291	Target Neighborhood Hits	221	Shared Neighborhood Hits	91
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.072712 (rank : 420)
Query Neighborhood Hits	291	Target Neighborhood Hits	221	Shared Neighborhood Hits	90
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PHXR5_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.070685 (rank : 426)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PROC_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.054555 (rank : 480)
Query Neighborhood Hits	291	Target Neighborhood Hits	426	Shared Neighborhood Hits	126
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROP_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.053627 (rank : 482)
Query Neighborhood Hits	291	Target Neighborhood Hits	126	Shared Neighborhood Hits	39
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.063178 (rank : 447)
Query Neighborhood Hits	291	Target Neighborhood Hits	165	Shared Neighborhood Hits	46
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROS_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.191389 (rank : 163)
Query Neighborhood Hits	291	Target Neighborhood Hits	340	Shared Neighborhood Hits	155
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.190666 (rank : 166)
Query Neighborhood Hits	291	Target Neighborhood Hits	330	Shared Neighborhood Hits	154
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.110748 (rank : 313)
Query Neighborhood Hits	291	Target Neighborhood Hits	422	Shared Neighborhood Hits	130
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 487)	NC score	0.111487 (rank : 312)
Query Neighborhood Hits	291	Target Neighborhood Hits	410	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RECK_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.073685 (rank : 416)
Query Neighborhood Hits	291	Target Neighborhood Hits	189	Shared Neighborhood Hits	69
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 489)	NC score	0.073850 (rank : 415)
Query Neighborhood Hits	291	Target Neighborhood Hits	158	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RELN_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.054584 (rank : 479)
Query Neighborhood Hits	291	Target Neighborhood Hits	233	Shared Neighborhood Hits	95
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 491)	NC score	0.056450 (rank : 467)
Query Neighborhood Hits	291	Target Neighborhood Hits	235	Shared Neighborhood Hits	96
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

SLIT2_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.141845 (rank : 255)
Query Neighborhood Hits	291	Target Neighborhood Hits	708	Shared Neighborhood Hits	163
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 493)	NC score	0.140156 (rank : 260)
Query Neighborhood Hits	291	Target Neighborhood Hits	684	Shared Neighborhood Hits	153
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SPON1_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.054874 (rank : 478)
Query Neighborhood Hits	291	Target Neighborhood Hits	117	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	θ > 10 (rank : 495)	NC score	0.056257 (rank : 468)
Query Neighborhood Hits	291	Target Neighborhood Hits	123	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SUSD1_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.160795 (rank : 222)
Query Neighborhood Hits	291	Target Neighborhood Hits	285	Shared Neighborhood Hits	119
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.073303 (rank : 419)
Query Neighborhood Hits	291	Target Neighborhood Hits	132	Shared Neighborhood Hits	69
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 498)	NC score	0.092440 (rank : 371)
Query Neighborhood Hits	291	Target Neighborhood Hits	146	Shared Neighborhood Hits	80
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.072544 (rank : 421)
Query Neighborhood Hits	291	Target Neighborhood Hits	131	Shared Neighborhood Hits	68
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TEFF2_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.072045 (rank : 422)
Query Neighborhood Hits	291	Target Neighborhood Hits	211	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.073623 (rank : 417)
Query Neighborhood Hits	291	Target Neighborhood Hits	214	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENA_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.196846 (rank : 155)
Query Neighborhood Hits	291	Target Neighborhood Hits	631	Shared Neighborhood Hits	177
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.188911 (rank : 170)
Query Neighborhood Hits	291	Target Neighborhood Hits	596	Shared Neighborhood Hits	169
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.093153 (rank : 368)
Query Neighborhood Hits	291	Target Neighborhood Hits	453	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.101269 (rank : 337)
Query Neighborhood Hits	291	Target Neighborhood Hits	484	Shared Neighborhood Hits	147
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.119511 (rank : 293)
Query Neighborhood Hits	291	Target Neighborhood Hits	531	Shared Neighborhood Hits	154
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TIE2_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.097642 (rank : 351)
Query Neighborhood Hits	291	Target Neighborhood Hits	1192	Shared Neighborhood Hits	164
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TLL1_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.078197 (rank : 403)
Query Neighborhood Hits	291	Target Neighborhood Hits	236	Shared Neighborhood Hits	94
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 509)	NC score	0.078718 (rank : 401)
Query Neighborhood Hits	291	Target Neighborhood Hits	237	Shared Neighborhood Hits	95
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 510)	NC score	0.075792 (rank : 406)
Query Neighborhood Hits	291	Target Neighborhood Hits	241	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TNR11_MOUSE
θ value	θ > 10 (rank : 511)	NC score	0.086857 (rank : 382)
Query Neighborhood Hits	291	Target Neighborhood Hits	121	Shared Neighborhood Hits	73
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR19_HUMAN
θ value	θ > 10 (rank : 512)	NC score	0.065277 (rank : 439)
Query Neighborhood Hits	291	Target Neighborhood Hits	89	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 513)	NC score	0.074057 (rank : 414)
Query Neighborhood Hits	291	Target Neighborhood Hits	100	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1B_HUMAN
θ value	θ > 10 (rank : 514)	NC score	0.108682 (rank : 320)
Query Neighborhood Hits	291	Target Neighborhood Hits	127	Shared Neighborhood Hits	67
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR21_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.080223 (rank : 400)
Query Neighborhood Hits	291	Target Neighborhood Hits	90	Shared Neighborhood Hits	58
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.069615 (rank : 429)
Query Neighborhood Hits	291	Target Neighborhood Hits	108	Shared Neighborhood Hits	57
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR22_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.121829 (rank : 289)
Query Neighborhood Hits	291	Target Neighborhood Hits	97	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR4_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.112737 (rank : 307)
Query Neighborhood Hits	291	Target Neighborhood Hits	152	Shared Neighborhood Hits	76
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR4_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.135570 (rank : 271)
Query Neighborhood Hits	291	Target Neighborhood Hits	137	Shared Neighborhood Hits	85
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR5_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.094772 (rank : 359)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	67
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR6B_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.092717 (rank : 369)
Query Neighborhood Hits	291	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR8_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.097719 (rank : 350)
Query Neighborhood Hits	291	Target Neighborhood Hits	198	Shared Neighborhood Hits	75
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.078532 (rank : 402)
Query Neighborhood Hits	291	Target Neighborhood Hits	208	Shared Neighborhood Hits	77
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TR10B_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.081726 (rank : 393)
Query Neighborhood Hits	291	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR11B_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.080658 (rank : 396)
Query Neighborhood Hits	291	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TSP2_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.136568 (rank : 268)
Query Neighborhood Hits	291	Target Neighborhood Hits	359	Shared Neighborhood Hits	148
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.160172 (rank : 225)
Query Neighborhood Hits	291	Target Neighborhood Hits	250	Shared Neighborhood Hits	133
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.162135 (rank : 220)
Query Neighborhood Hits	291	Target Neighborhood Hits	247	Shared Neighborhood Hits	140
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.167520 (rank : 212)
Query Neighborhood Hits	291	Target Neighborhood Hits	277	Shared Neighborhood Hits	145
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.173473 (rank : 200)
Query Neighborhood Hits	291	Target Neighborhood Hits	276	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROL1_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.064689 (rank : 441)
Query Neighborhood Hits	291	Target Neighborhood Hits	213	Shared Neighborhood Hits	81
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.069852 (rank : 428)
Query Neighborhood Hits	291	Target Neighborhood Hits	235	Shared Neighborhood Hits	86
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.198295 (rank : 153)
Query Neighborhood Hits	291	Target Neighborhood Hits	284	Shared Neighborhood Hits	147
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.201801 (rank : 150)
Query Neighborhood Hits	291	Target Neighborhood Hits	276	Shared Neighborhood Hits	147
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VEGFC_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.075755 (rank : 407)
Query Neighborhood Hits	291	Target Neighborhood Hits	128	Shared Neighborhood Hits	74
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VEGFC_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.064111 (rank : 443)
Query Neighborhood Hits	291	Target Neighborhood Hits	119	Shared Neighborhood Hits	66
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

VLDLR_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.160427 (rank : 223)
Query Neighborhood Hits	291	Target Neighborhood Hits	383	Shared Neighborhood Hits	148
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.160177 (rank : 224)
Query Neighborhood Hits	291	Target Neighborhood Hits	360	Shared Neighborhood Hits	146
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WFDC3_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.054108 (rank : 481)
Query Neighborhood Hits	291	Target Neighborhood Hits	138	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WIF1_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.221838 (rank : 116)
Query Neighborhood Hits	291	Target Neighborhood Hits	393	Shared Neighborhood Hits	167
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

Hits sorted by NC score

PCSK5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	291	Target Neighborhood Hits	291	Shared Neighborhood Hits	291
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK6_HUMAN
NC score	0.958747 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	291	Target Neighborhood Hits	298	Shared Neighborhood Hits	177
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

PCSK5_MOUSE
NC score	0.907094 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	291	Target Neighborhood Hits	613	Shared Neighborhood Hits	270
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

FURIN_MOUSE
NC score	0.892481 (rank : 4)	θ value	5.00115e-184 (rank : 5)
Query Neighborhood Hits	291	Target Neighborhood Hits	49	Shared Neighborhood Hits	40
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

FURIN_HUMAN
NC score	0.890952 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	291	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

PCSK4_HUMAN
NC score	0.879181 (rank : 6)	θ value	2.17943e-171 (rank : 6)
Query Neighborhood Hits	291	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PCSK4_MOUSE
NC score	0.866352 (rank : 7)	θ value	1.79118e-157 (rank : 7)
Query Neighborhood Hits	291	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

NEC1_MOUSE
NC score	0.862701 (rank : 8)	θ value	2.18956e-155 (rank : 9)
Query Neighborhood Hits	291	Target Neighborhood Hits	16	Shared Neighborhood Hits	15
SwissProt Accessions	P63239, P21662, P22546	Gene names	Pcsk1, Att-1, Nec-1, Nec1
Domain Architecture	No domain graphic available
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1) (PC3) (Furin homolog) (Propeptide-processing protease).

NEC1_HUMAN
NC score	0.862666 (rank : 9)	θ value	1.16101e-156 (rank : 8)
Query Neighborhood Hits	291	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	P29120, P78478, Q92532	Gene names	PCSK1, NEC1
Domain Architecture
Description	Neuroendocrine convertase 1 precursor (EC 3.4.21.93) (NEC 1) (PC1) (Prohormone convertase 1) (Proprotein convertase 1).

NEC2_MOUSE
NC score	0.859375 (rank : 10)	θ value	1.92707e-135 (rank : 10)
Query Neighborhood Hits	291	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P21661, Q80WU1	Gene names	Pcsk2, Nec-2, Nec2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

NEC2_HUMAN
NC score	0.859147 (rank : 11)	θ value	7.32286e-135 (rank : 11)
Query Neighborhood Hits	291	Target Neighborhood Hits	23	Shared Neighborhood Hits	16
SwissProt Accessions	P16519, Q14927, Q9NQG3, Q9NUG1, Q9UJC6	Gene names	PCSK2, NEC2
Domain Architecture
Description	Neuroendocrine convertase 2 precursor (EC 3.4.21.94) (NEC 2) (PC2) (Prohormone convertase 2) (Proprotein convertase 2) (KEX2-like endoprotease 2).

PCSK7_HUMAN
NC score	0.852512 (rank : 12)	θ value	5.44333e-122 (rank : 13)
Query Neighborhood Hits	291	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q16549, Q9UL57	Gene names	PCSK7, LPC, PC7, PC8, SPC7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (PC8) (hPC8) (Lymphoma proprotein convertase).

PCSK7_MOUSE
NC score	0.852362 (rank : 13)	θ value	8.39787e-123 (rank : 12)
Query Neighborhood Hits	291	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

FRAS1_HUMAN
NC score	0.411178 (rank : 14)	θ value	8.06329e-33 (rank : 15)
Query Neighborhood Hits	291	Target Neighborhood Hits	759	Shared Neighborhood Hits	229
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
NC score	0.406059 (rank : 15)	θ value	4.72714e-33 (rank : 14)
Query Neighborhood Hits	291	Target Neighborhood Hits	747	Shared Neighborhood Hits	235
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CREL1_HUMAN
NC score	0.343455 (rank : 16)	θ value	1.53129e-07 (rank : 31)
Query Neighborhood Hits	291	Target Neighborhood Hits	441	Shared Neighborhood Hits	181
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
NC score	0.341020 (rank : 17)	θ value	3.08544e-08 (rank : 24)
Query Neighborhood Hits	291	Target Neighborhood Hits	524	Shared Neighborhood Hits	193
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

RSPO3_HUMAN
NC score	0.338720 (rank : 18)	θ value	8.97725e-08 (rank : 29)
Query Neighborhood Hits	291	Target Neighborhood Hits	128	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
NC score	0.333171 (rank : 19)	θ value	5.26297e-08 (rank : 27)
Query Neighborhood Hits	291	Target Neighborhood Hits	120	Shared Neighborhood Hits	78
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
NC score	0.327876 (rank : 20)	θ value	1.53129e-07 (rank : 32)
Query Neighborhood Hits	291	Target Neighborhood Hits	110	Shared Neighborhood Hits	77
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
NC score	0.325047 (rank : 21)	θ value	4.92598e-06 (rank : 41)
Query Neighborhood Hits	291	Target Neighborhood Hits	110	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

MEGF9_HUMAN
NC score	0.322226 (rank : 22)	θ value	1.06045e-08 (rank : 22)
Query Neighborhood Hits	291	Target Neighborhood Hits	557	Shared Neighborhood Hits	184
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SREC2_MOUSE
NC score	0.319812 (rank : 23)	θ value	4.92598e-06 (rank : 42)
Query Neighborhood Hits	291	Target Neighborhood Hits	605	Shared Neighborhood Hits	202
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
NC score	0.315991 (rank : 24)	θ value	4.1701e-05 (rank : 55)
Query Neighborhood Hits	291	Target Neighborhood Hits	645	Shared Neighborhood Hits	207
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

MEGF6_HUMAN
NC score	0.315535 (rank : 25)	θ value	9.29e-05 (rank : 59)
Query Neighborhood Hits	291	Target Neighborhood Hits	671	Shared Neighborhood Hits	230
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KRA51_HUMAN
NC score	0.314954 (rank : 26)	θ value	3.0926 (rank : 235)
Query Neighborhood Hits	291	Target Neighborhood Hits	288	Shared Neighborhood Hits	136
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

SREC2_HUMAN
NC score	0.313780 (rank : 27)	θ value	0.00390308 (rank : 99)
Query Neighborhood Hits	291	Target Neighborhood Hits	645	Shared Neighborhood Hits	199
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

MEGF9_MOUSE
NC score	0.313632 (rank : 28)	θ value	3.89403e-11 (rank : 17)
Query Neighborhood Hits	291	Target Neighborhood Hits	896	Shared Neighborhood Hits	181
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

RSPO2_MOUSE
NC score	0.313621 (rank : 29)	θ value	1.17247e-07 (rank : 30)
Query Neighborhood Hits	291	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO2_HUMAN
NC score	0.313270 (rank : 30)	θ value	1.99992e-07 (rank : 33)
Query Neighborhood Hits	291	Target Neighborhood Hits	90	Shared Neighborhood Hits	59
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

MEGF8_HUMAN
NC score	0.307263 (rank : 31)	θ value	1.43324e-05 (rank : 48)
Query Neighborhood Hits	291	Target Neighborhood Hits	528	Shared Neighborhood Hits	187
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

RSPO1_HUMAN
NC score	0.306858 (rank : 32)	θ value	8.11959e-09 (rank : 21)
Query Neighborhood Hits	291	Target Neighborhood Hits	101	Shared Neighborhood Hits	64
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

MEGF8_MOUSE
NC score	0.303741 (rank : 33)	θ value	8.40245e-06 (rank : 46)
Query Neighborhood Hits	291	Target Neighborhood Hits	520	Shared Neighborhood Hits	186
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KRA59_HUMAN
NC score	0.299660 (rank : 34)	θ value	2.36792 (rank : 230)
Query Neighborhood Hits	291	Target Neighborhood Hits	310	Shared Neighborhood Hits	135
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA53_HUMAN
NC score	0.295941 (rank : 35)	θ value	0.125558 (rank : 155)
Query Neighborhood Hits	291	Target Neighborhood Hits	331	Shared Neighborhood Hits	153
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA55_HUMAN
NC score	0.292865 (rank : 36)	θ value	6.88961 (rank : 273)
Query Neighborhood Hits	291	Target Neighborhood Hits	257	Shared Neighborhood Hits	120
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

RSPO1_MOUSE
NC score	0.288568 (rank : 37)	θ value	5.26297e-08 (rank : 26)
Query Neighborhood Hits	291	Target Neighborhood Hits	85	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

KRA54_HUMAN
NC score	0.278825 (rank : 38)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	291	Target Neighborhood Hits	270	Shared Neighborhood Hits	122
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

NELL1_HUMAN
NC score	0.275766 (rank : 39)	θ value	0.00035302 (rank : 67)
Query Neighborhood Hits	291	Target Neighborhood Hits	451	Shared Neighborhood Hits	186
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

ZAN_MOUSE
NC score	0.275301 (rank : 40)	θ value	0.00035302 (rank : 68)
Query Neighborhood Hits	291	Target Neighborhood Hits	808	Shared Neighborhood Hits	228
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LAMB2_HUMAN
NC score	0.274769 (rank : 41)	θ value	0.00228821 (rank : 93)
Query Neighborhood Hits	291	Target Neighborhood Hits	692	Shared Neighborhood Hits	182
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMC3_HUMAN
NC score	0.272383 (rank : 42)	θ value	0.000602161 (rank : 75)
Query Neighborhood Hits	291	Target Neighborhood Hits	588	Shared Neighborhood Hits	187
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_MOUSE
NC score	0.271839 (rank : 43)	θ value	4.45536e-07 (rank : 37)
Query Neighborhood Hits	291	Target Neighborhood Hits	828	Shared Neighborhood Hits	211
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NELL2_HUMAN
NC score	0.271321 (rank : 44)	θ value	5.81887e-07 (rank : 38)
Query Neighborhood Hits	291	Target Neighborhood Hits	449	Shared Neighborhood Hits	178
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

LAMA1_MOUSE
NC score	0.270637 (rank : 45)	θ value	3.19293e-05 (rank : 52)
Query Neighborhood Hits	291	Target Neighborhood Hits	838	Shared Neighborhood Hits	208
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NELL2_MOUSE
NC score	0.269994 (rank : 46)	θ value	2.88788e-06 (rank : 40)
Query Neighborhood Hits	291	Target Neighborhood Hits	436	Shared Neighborhood Hits	176
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

LAMA1_HUMAN
NC score	0.269612 (rank : 47)	θ value	0.00035302 (rank : 65)
Query Neighborhood Hits	291	Target Neighborhood Hits	804	Shared Neighborhood Hits	204
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_MOUSE
NC score	0.268777 (rank : 48)	θ value	0.00175202 (rank : 89)
Query Neighborhood Hits	291	Target Neighborhood Hits	722	Shared Neighborhood Hits	183
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC3_MOUSE
NC score	0.268632 (rank : 49)	θ value	0.000786445 (rank : 77)
Query Neighborhood Hits	291	Target Neighborhood Hits	624	Shared Neighborhood Hits	194
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

KRA58_HUMAN
NC score	0.268123 (rank : 50)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	291	Target Neighborhood Hits	324	Shared Neighborhood Hits	140
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMA5_HUMAN
NC score	0.267610 (rank : 51)	θ value	0.0330416 (rank : 135)
Query Neighborhood Hits	291	Target Neighborhood Hits	976	Shared Neighborhood Hits	214
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

SCUB3_MOUSE
NC score	0.266068 (rank : 52)	θ value	3.19293e-05 (rank : 53)
Query Neighborhood Hits	291	Target Neighborhood Hits	442	Shared Neighborhood Hits	199
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.265540 (rank : 53)	θ value	1.87187e-05 (rank : 49)
Query Neighborhood Hits	291	Target Neighborhood Hits	428	Shared Neighborhood Hits	197
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

CRIM1_HUMAN
NC score	0.261957 (rank : 54)	θ value	0.00228821 (rank : 91)
Query Neighborhood Hits	291	Target Neighborhood Hits	362	Shared Neighborhood Hits	151
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

LTBP2_MOUSE
NC score	0.261038 (rank : 55)	θ value	0.000461057 (rank : 72)
Query Neighborhood Hits	291	Target Neighborhood Hits	617	Shared Neighborhood Hits	195
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KRA52_HUMAN
NC score	0.260415 (rank : 56)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	291	Target Neighborhood Hits	236	Shared Neighborhood Hits	112
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

STAB2_HUMAN
NC score	0.259838 (rank : 57)	θ value	0.00869519 (rank : 115)
Query Neighborhood Hits	291	Target Neighborhood Hits	534	Shared Neighborhood Hits	192
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB1_HUMAN
NC score	0.259655 (rank : 58)	θ value	0.00102713 (rank : 83)
Query Neighborhood Hits	291	Target Neighborhood Hits	546	Shared Neighborhood Hits	193
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

FBN3_HUMAN
NC score	0.259428 (rank : 59)	θ value	0.0563607 (rank : 142)
Query Neighborhood Hits	291	Target Neighborhood Hits	543	Shared Neighborhood Hits	197
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

STAB1_MOUSE
NC score	0.259385 (rank : 60)	θ value	0.00134147 (rank : 86)
Query Neighborhood Hits	291	Target Neighborhood Hits	566	Shared Neighborhood Hits	192
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

FBN1_HUMAN
NC score	0.258713 (rank : 61)	θ value	0.00390308 (rank : 97)
Query Neighborhood Hits	291	Target Neighborhood Hits	557	Shared Neighborhood Hits	204
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
NC score	0.257645 (rank : 62)	θ value	0.000461057 (rank : 70)
Query Neighborhood Hits	291	Target Neighborhood Hits	560	Shared Neighborhood Hits	198
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.256991 (rank : 63)	θ value	0.00869519 (rank : 113)
Query Neighborhood Hits	291	Target Neighborhood Hits	563	Shared Neighborhood Hits	202
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

STAB2_MOUSE
NC score	0.256858 (rank : 64)	θ value	0.0148317 (rank : 122)
Query Neighborhood Hits	291	Target Neighborhood Hits	528	Shared Neighborhood Hits	192
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

LAMB1_MOUSE
NC score	0.255983 (rank : 65)	θ value	5.26297e-08 (rank : 25)
Query Neighborhood Hits	291	Target Neighborhood Hits	919	Shared Neighborhood Hits	173
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

FBN2_MOUSE
NC score	0.254880 (rank : 66)	θ value	0.00020696 (rank : 61)
Query Neighborhood Hits	291	Target Neighborhood Hits	549	Shared Neighborhood Hits	202
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LAMC2_MOUSE
NC score	0.254454 (rank : 67)	θ value	0.00228821 (rank : 94)
Query Neighborhood Hits	291	Target Neighborhood Hits	614	Shared Neighborhood Hits	190
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LTBP4_MOUSE
NC score	0.252537 (rank : 68)	θ value	0.813845 (rank : 193)
Query Neighborhood Hits	291	Target Neighborhood Hits	607	Shared Neighborhood Hits	187
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTBP2_HUMAN
NC score	0.252114 (rank : 69)	θ value	0.0113563 (rank : 120)
Query Neighborhood Hits	291	Target Neighborhood Hits	552	Shared Neighborhood Hits	192
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

USH2A_MOUSE
NC score	0.251243 (rank : 70)	θ value	3.19293e-05 (rank : 54)
Query Neighborhood Hits	291	Target Neighborhood Hits	626	Shared Neighborhood Hits	188
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

KR510_HUMAN
NC score	0.251106 (rank : 71)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	291	Target Neighborhood Hits	217	Shared Neighborhood Hits	96
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

LAMA2_HUMAN
NC score	0.247050 (rank : 72)	θ value	0.000602161 (rank : 74)
Query Neighborhood Hits	291	Target Neighborhood Hits	1092	Shared Neighborhood Hits	201
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC1_MOUSE
NC score	0.244592 (rank : 73)	θ value	0.00509761 (rank : 103)
Query Neighborhood Hits	291	Target Neighborhood Hits	856	Shared Neighborhood Hits	182
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

JAG1_HUMAN
NC score	0.244389 (rank : 74)	θ value	0.365318 (rank : 175)
Query Neighborhood Hits	291	Target Neighborhood Hits	514	Shared Neighborhood Hits	177
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

LAMB1_HUMAN
NC score	0.243498 (rank : 75)	θ value	2.44474e-05 (rank : 50)
Query Neighborhood Hits	291	Target Neighborhood Hits	1018	Shared Neighborhood Hits	176
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

FBLN2_HUMAN
NC score	0.243197 (rank : 76)	θ value	0.0193708 (rank : 125)
Query Neighborhood Hits	291	Target Neighborhood Hits	392	Shared Neighborhood Hits	164
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LAMB3_MOUSE
NC score	0.242722 (rank : 77)	θ value	0.813845 (rank : 192)
Query Neighborhood Hits	291	Target Neighborhood Hits	444	Shared Neighborhood Hits	146
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

KRA57_HUMAN
NC score	0.242476 (rank : 78)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	291	Target Neighborhood Hits	269	Shared Neighborhood Hits	121
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

JAG1_MOUSE
NC score	0.242407 (rank : 79)	θ value	1.38821 (rank : 209)
Query Neighborhood Hits	291	Target Neighborhood Hits	518	Shared Neighborhood Hits	176
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
NC score	0.241547 (rank : 80)	θ value	0.0113563 (rank : 117)
Query Neighborhood Hits	291	Target Neighborhood Hits	491	Shared Neighborhood Hits	172
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

FBLN2_MOUSE
NC score	0.241435 (rank : 81)	θ value	0.00869519 (rank : 111)
Query Neighborhood Hits	291	Target Neighborhood Hits	505	Shared Neighborhood Hits	167
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

LAMC1_HUMAN
NC score	0.241378 (rank : 82)	θ value	0.00035302 (rank : 66)
Query Neighborhood Hits	291	Target Neighborhood Hits	922	Shared Neighborhood Hits	178
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

DLL4_MOUSE
NC score	0.240226 (rank : 83)	θ value	0.0736092 (rank : 148)
Query Neighborhood Hits	291	Target Neighborhood Hits	440	Shared Neighborhood Hits	177
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC1_MOUSE
NC score	0.239175 (rank : 84)	θ value	0.00665767 (rank : 108)
Query Neighborhood Hits	291	Target Neighborhood Hits	916	Shared Neighborhood Hits	195
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LTB1S_HUMAN
NC score	0.239082 (rank : 85)	θ value	0.163984 (rank : 164)
Query Neighborhood Hits	291	Target Neighborhood Hits	502	Shared Neighborhood Hits	176
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.238958 (rank : 86)	θ value	0.163984 (rank : 163)
Query Neighborhood Hits	291	Target Neighborhood Hits	553	Shared Neighborhood Hits	179
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN1_MOUSE
NC score	0.238837 (rank : 87)	θ value	0.0193708 (rank : 124)
Query Neighborhood Hits	291	Target Neighborhood Hits	329	Shared Neighborhood Hits	164
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

JAG2_MOUSE
NC score	0.238631 (rank : 88)	θ value	0.125558 (rank : 154)
Query Neighborhood Hits	291	Target Neighborhood Hits	504	Shared Neighborhood Hits	173
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

MATN2_HUMAN
NC score	0.237803 (rank : 89)	θ value	8.97725e-08 (rank : 28)
Query Neighborhood Hits	291	Target Neighborhood Hits	365	Shared Neighborhood Hits	161
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

KRA56_HUMAN
NC score	0.237645 (rank : 90)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	291	Target Neighborhood Hits	207	Shared Neighborhood Hits	105
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LAMC2_HUMAN
NC score	0.237270 (rank : 91)	θ value	0.000270298 (rank : 62)
Query Neighborhood Hits	291	Target Neighborhood Hits	715	Shared Neighborhood Hits	176
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

DLL1_MOUSE
NC score	0.236685 (rank : 92)	θ value	0.00035302 (rank : 64)
Query Neighborhood Hits	291	Target Neighborhood Hits	456	Shared Neighborhood Hits	181
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

LTB1S_MOUSE
NC score	0.235886 (rank : 93)	θ value	0.0563607 (rank : 144)
Query Neighborhood Hits	291	Target Neighborhood Hits	479	Shared Neighborhood Hits	178
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LAMB3_HUMAN
NC score	0.235656 (rank : 94)	θ value	0.000461057 (rank : 71)
Query Neighborhood Hits	291	Target Neighborhood Hits	461	Shared Neighborhood Hits	137
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMA2_MOUSE
NC score	0.235337 (rank : 95)	θ value	6.43352e-06 (rank : 44)
Query Neighborhood Hits	291	Target Neighborhood Hits	1198	Shared Neighborhood Hits	197
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LTB1L_MOUSE
NC score	0.234657 (rank : 96)	θ value	0.0563607 (rank : 143)
Query Neighborhood Hits	291	Target Neighborhood Hits	514	Shared Neighborhood Hits	181
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN1_HUMAN
NC score	0.234637 (rank : 97)	θ value	0.00665767 (rank : 106)
Query Neighborhood Hits	291	Target Neighborhood Hits	324	Shared Neighborhood Hits	158
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

MATN2_MOUSE
NC score	0.234568 (rank : 98)	θ value	7.1131e-05 (rank : 58)
Query Neighborhood Hits	291	Target Neighborhood Hits	356	Shared Neighborhood Hits	160
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

LTBP3_MOUSE
NC score	0.233816 (rank : 99)	θ value	0.279714 (rank : 171)
Query Neighborhood Hits	291	Target Neighborhood Hits	475	Shared Neighborhood Hits	182
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

USH2A_HUMAN
NC score	0.233700 (rank : 100)	θ value	0.000786445 (rank : 79)
Query Neighborhood Hits	291	Target Neighborhood Hits	600	Shared Neighborhood Hits	184
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

DLL4_HUMAN
NC score	0.233694 (rank : 101)	θ value	0.163984 (rank : 160)
Query Neighborhood Hits	291	Target Neighborhood Hits	435	Shared Neighborhood Hits	174
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC1_HUMAN
NC score	0.232908 (rank : 102)	θ value	0.0193708 (rank : 126)
Query Neighborhood Hits	291	Target Neighborhood Hits	906	Shared Neighborhood Hits	196
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DLL1_HUMAN
NC score	0.232313 (rank : 103)	θ value	0.00102713 (rank : 80)
Query Neighborhood Hits	291	Target Neighborhood Hits	455	Shared Neighborhood Hits	180
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

TRBM_MOUSE
NC score	0.230789 (rank : 104)	θ value	0.00390308 (rank : 101)
Query Neighborhood Hits	291	Target Neighborhood Hits	361	Shared Neighborhood Hits	161
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

FBLN5_MOUSE
NC score	0.230328 (rank : 105)	θ value	0.000602161 (rank : 73)
Query Neighborhood Hits	291	Target Neighborhood Hits	317	Shared Neighborhood Hits	159
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

LAMA3_MOUSE
NC score	0.229870 (rank : 106)	θ value	0.0431538 (rank : 138)
Query Neighborhood Hits	291	Target Neighborhood Hits	859	Shared Neighborhood Hits	192
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LTBP3_HUMAN
NC score	0.229169 (rank : 107)	θ value	5.27518 (rank : 255)
Query Neighborhood Hits	291	Target Neighborhood Hits	502	Shared Neighborhood Hits	179
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NOTC3_HUMAN
NC score	0.227405 (rank : 108)	θ value	0.62314 (rank : 184)
Query Neighborhood Hits	291	Target Neighborhood Hits	1062	Shared Neighborhood Hits	194
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

KR511_HUMAN
NC score	0.226277 (rank : 109)	θ value	2.36792 (rank : 229)
Query Neighborhood Hits	291	Target Neighborhood Hits	231	Shared Neighborhood Hits	104
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

AGRIN_HUMAN
NC score	0.225443 (rank : 110)	θ value	0.0563607 (rank : 141)
Query Neighborhood Hits	291	Target Neighborhood Hits	582	Shared Neighborhood Hits	168
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FBLN5_HUMAN
NC score	0.225431 (rank : 111)	θ value	0.279714 (rank : 169)
Query Neighborhood Hits	291	Target Neighborhood Hits	329	Shared Neighborhood Hits	159
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

DNER_HUMAN
NC score	0.224678 (rank : 112)	θ value	0.21417 (rank : 165)
Query Neighborhood Hits	291	Target Neighborhood Hits	460	Shared Neighborhood Hits	159
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

NOTC3_MOUSE
NC score	0.224301 (rank : 113)	θ value	1.81305 (rank : 218)
Query Neighborhood Hits	291	Target Neighborhood Hits	975	Shared Neighborhood Hits	189
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TRBM_HUMAN
NC score	0.224146 (rank : 114)	θ value	0.279714 (rank : 173)
Query Neighborhood Hits	291	Target Neighborhood Hits	339	Shared Neighborhood Hits	152
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NOTC4_HUMAN
NC score	0.223267 (rank : 115)	θ value	0.21417 (rank : 167)
Query Neighborhood Hits	291	Target Neighborhood Hits	905	Shared Neighborhood Hits	189
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

WIF1_MOUSE
NC score	0.221838 (rank : 116)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	291	Target Neighborhood Hits	393	Shared Neighborhood Hits	167
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

NOTC2_MOUSE
NC score	0.221507 (rank : 117)	θ value	0.0252991 (rank : 131)
Query Neighborhood Hits	291	Target Neighborhood Hits	1069	Shared Neighborhood Hits	181
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

C1QR1_HUMAN
NC score	0.220740 (rank : 118)	θ value	0.0252991 (rank : 128)
Query Neighborhood Hits	291	Target Neighborhood Hits	493	Shared Neighborhood Hits	150
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

NOTC2_HUMAN
NC score	0.219395 (rank : 119)	θ value	5.27518 (rank : 256)
Query Neighborhood Hits	291	Target Neighborhood Hits	1113	Shared Neighborhood Hits	193
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_MOUSE
NC score	0.219014 (rank : 120)	θ value	0.125558 (rank : 156)
Query Neighborhood Hits	291	Target Neighborhood Hits	872	Shared Neighborhood Hits	187
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

CRUM1_HUMAN
NC score	0.218423 (rank : 121)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	291	Target Neighborhood Hits	457	Shared Neighborhood Hits	167
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DNER_MOUSE
NC score	0.218207 (rank : 122)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	291	Target Neighborhood Hits	413	Shared Neighborhood Hits	156
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

CRUM1_MOUSE
NC score	0.217990 (rank : 123)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	291	Target Neighborhood Hits	444	Shared Neighborhood Hits	169
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DLL3_HUMAN
NC score	0.217823 (rank : 124)	θ value	0.00102713 (rank : 81)
Query Neighborhood Hits	291	Target Neighborhood Hits	419	Shared Neighborhood Hits	156
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

WIF1_HUMAN
NC score	0.216513 (rank : 125)	θ value	2.36792 (rank : 232)
Query Neighborhood Hits	291	Target Neighborhood Hits	392	Shared Neighborhood Hits	168
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

DLK_HUMAN
NC score	0.215976 (rank : 126)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	291	Target Neighborhood Hits	401	Shared Neighborhood Hits	169
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

NTNG2_HUMAN
NC score	0.215789 (rank : 127)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	291	Target Neighborhood Hits	276	Shared Neighborhood Hits	135
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

DLL3_MOUSE
NC score	0.215680 (rank : 128)	θ value	5.27518 (rank : 253)
Query Neighborhood Hits	291	Target Neighborhood Hits	399	Shared Neighborhood Hits	162
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

FBLN4_MOUSE
NC score	0.215654 (rank : 129)	θ value	0.00869519 (rank : 112)
Query Neighborhood Hits	291	Target Neighborhood Hits	270	Shared Neighborhood Hits	138
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

KR104_HUMAN
NC score	0.215626 (rank : 130)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	291	Target Neighborhood Hits	313	Shared Neighborhood Hits	140
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

CRUM2_HUMAN
NC score	0.215462 (rank : 131)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	291	Target Neighborhood Hits	453	Shared Neighborhood Hits	171
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

FBLN4_HUMAN
NC score	0.214934 (rank : 132)	θ value	0.0113563 (rank : 116)
Query Neighborhood Hits	291	Target Neighborhood Hits	278	Shared Neighborhood Hits	140
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

EGFL9_HUMAN
NC score	0.214912 (rank : 133)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	291	Target Neighborhood Hits	365	Shared Neighborhood Hits	162
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

DLK_MOUSE
NC score	0.214294 (rank : 134)	θ value	4.03905 (rank : 244)
Query Neighborhood Hits	291	Target Neighborhood Hits	374	Shared Neighborhood Hits	158
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

NID2_HUMAN
NC score	0.213350 (rank : 135)	θ value	0.00134147 (rank : 85)
Query Neighborhood Hits	291	Target Neighborhood Hits	456	Shared Neighborhood Hits	163
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

EGFL9_MOUSE
NC score	0.213245 (rank : 136)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	291	Target Neighborhood Hits	379	Shared Neighborhood Hits	161
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

C1QR1_MOUSE
NC score	0.211372 (rank : 137)	θ value	4.03905 (rank : 242)
Query Neighborhood Hits	291	Target Neighborhood Hits	342	Shared Neighborhood Hits	156
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

KR107_HUMAN
NC score	0.211259 (rank : 138)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	291	Target Neighborhood Hits	330	Shared Neighborhood Hits	146
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR106_HUMAN
NC score	0.210579 (rank : 139)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	291	Target Neighborhood Hits	347	Shared Neighborhood Hits	154
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

NTNG1_HUMAN
NC score	0.210285 (rank : 140)	θ value	0.00869519 (rank : 114)
Query Neighborhood Hits	291	Target Neighborhood Hits	247	Shared Neighborhood Hits	129
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_MOUSE
NC score	0.208808 (rank : 141)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	291	Target Neighborhood Hits	276	Shared Neighborhood Hits	138
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

CUBN_HUMAN
NC score	0.208728 (rank : 142)	θ value	0.000786445 (rank : 76)
Query Neighborhood Hits	291	Target Neighborhood Hits	482	Shared Neighborhood Hits	168
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

LAMA3_HUMAN
NC score	0.208164 (rank : 143)	θ value	0.0431538 (rank : 137)
Query Neighborhood Hits	291	Target Neighborhood Hits	760	Shared Neighborhood Hits	168
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

FBLN3_HUMAN
NC score	0.207976 (rank : 144)	θ value	2.36792 (rank : 227)
Query Neighborhood Hits	291	Target Neighborhood Hits	293	Shared Neighborhood Hits	150
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

NTNG1_MOUSE
NC score	0.207904 (rank : 145)	θ value	0.0563607 (rank : 145)
Query Neighborhood Hits	291	Target Neighborhood Hits	246	Shared Neighborhood Hits	131
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LAMA4_MOUSE
NC score	0.207647 (rank : 146)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	291	Target Neighborhood Hits	584	Shared Neighborhood Hits	150
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

CUBN_MOUSE
NC score	0.205624 (rank : 147)	θ value	0.000461057 (rank : 69)
Query Neighborhood Hits	291	Target Neighborhood Hits	477	Shared Neighborhood Hits	175
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

LRP1_HUMAN
NC score	0.203451 (rank : 148)	θ value	0.0252991 (rank : 130)
Query Neighborhood Hits	291	Target Neighborhood Hits	617	Shared Neighborhood Hits	195
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

SSPO_MOUSE
NC score	0.202288 (rank : 149)	θ value	0.813845 (rank : 197)
Query Neighborhood Hits	291	Target Neighborhood Hits	800	Shared Neighborhood Hits	225
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

UROM_MOUSE
NC score	0.201801 (rank : 150)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	291	Target Neighborhood Hits	276	Shared Neighborhood Hits	147
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

TENX_HUMAN
NC score	0.201222 (rank : 151)	θ value	0.813845 (rank : 198)
Query Neighborhood Hits	291	Target Neighborhood Hits	789	Shared Neighborhood Hits	183
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

FBLN3_MOUSE
NC score	0.199713 (rank : 152)	θ value	2.36792 (rank : 228)
Query Neighborhood Hits	291	Target Neighborhood Hits	279	Shared Neighborhood Hits	134
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

UROM_HUMAN
NC score	0.198295 (rank : 153)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	291	Target Neighborhood Hits	284	Shared Neighborhood Hits	147
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

LRP1B_HUMAN
NC score	0.197093 (rank : 154)	θ value	0.0113563 (rank : 118)
Query Neighborhood Hits	291	Target Neighborhood Hits	602	Shared Neighborhood Hits	186
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TENA_HUMAN
NC score	0.196846 (rank : 155)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	291	Target Neighborhood Hits	631	Shared Neighborhood Hits	177
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

LAMA4_HUMAN
NC score	0.196597 (rank : 156)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	291	Target Neighborhood Hits	708	Shared Neighborhood Hits	141
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LRP1B_MOUSE
NC score	0.195605 (rank : 157)	θ value	0.0113563 (rank : 119)
Query Neighborhood Hits	291	Target Neighborhood Hits	606	Shared Neighborhood Hits	183
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP2_HUMAN
NC score	0.194999 (rank : 158)	θ value	0.00134147 (rank : 84)
Query Neighborhood Hits	291	Target Neighborhood Hits	573	Shared Neighborhood Hits	188
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

NID2_MOUSE
NC score	0.194115 (rank : 159)	θ value	1.06291 (rank : 201)
Query Neighborhood Hits	291	Target Neighborhood Hits	338	Shared Neighborhood Hits	149
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NET2_HUMAN
NC score	0.192572 (rank : 160)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	291	Target Neighborhood Hits	194	Shared Neighborhood Hits	106
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NAGPA_HUMAN
NC score	0.192268 (rank : 161)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	291	Target Neighborhood Hits	282	Shared Neighborhood Hits	133
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

MATN3_HUMAN
NC score	0.192221 (rank : 162)	θ value	0.00102713 (rank : 82)
Query Neighborhood Hits	291	Target Neighborhood Hits	268	Shared Neighborhood Hits	125
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

PROS_HUMAN
NC score	0.191389 (rank : 163)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	291	Target Neighborhood Hits	340	Shared Neighborhood Hits	155
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

ITB5_MOUSE
NC score	0.191337 (rank : 164)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	291	Target Neighborhood Hits	329	Shared Neighborhood Hits	171
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

NID1_MOUSE
NC score	0.191110 (rank : 165)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	291	Target Neighborhood Hits	335	Shared Neighborhood Hits	146
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PROS_MOUSE
NC score	0.190666 (rank : 166)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	291	Target Neighborhood Hits	330	Shared Neighborhood Hits	154
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

NET2_MOUSE
NC score	0.190103 (rank : 167)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	291	Target Neighborhood Hits	193	Shared Neighborhood Hits	110
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NID1_HUMAN
NC score	0.190099 (rank : 168)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	291	Target Neighborhood Hits	329	Shared Neighborhood Hits	148
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

EGF_MOUSE
NC score	0.189330 (rank : 169)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	291	Target Neighborhood Hits	358	Shared Neighborhood Hits	160
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

TENA_MOUSE
NC score	0.188911 (rank : 170)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	291	Target Neighborhood Hits	596	Shared Neighborhood Hits	169
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

ITB3_HUMAN
NC score	0.188734 (rank : 171)	θ value	0.0252991 (rank : 129)
Query Neighborhood Hits	291	Target Neighborhood Hits	325	Shared Neighborhood Hits	171
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

MATN4_MOUSE
NC score	0.188450 (rank : 172)	θ value	0.000786445 (rank : 78)
Query Neighborhood Hits	291	Target Neighborhood Hits	277	Shared Neighborhood Hits	134
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

ITB5_HUMAN
NC score	0.188255 (rank : 173)	θ value	0.47712 (rank : 180)
Query Neighborhood Hits	291	Target Neighborhood Hits	310	Shared Neighborhood Hits	164
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

KR171_HUMAN
NC score	0.188194 (rank : 174)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	291	Target Neighborhood Hits	144	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

ATRN_MOUSE
NC score	0.188159 (rank : 175)	θ value	2.36792 (rank : 222)
Query Neighborhood Hits	291	Target Neighborhood Hits	519	Shared Neighborhood Hits	158
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

NET4_MOUSE
NC score	0.187653 (rank : 176)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	291	Target Neighborhood Hits	180	Shared Neighborhood Hits	106
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

ITB7_HUMAN
NC score	0.186677 (rank : 177)	θ value	0.0148317 (rank : 121)
Query Neighborhood Hits	291	Target Neighborhood Hits	290	Shared Neighborhood Hits	157
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

EGF_HUMAN
NC score	0.186163 (rank : 178)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	291	Target Neighborhood Hits	343	Shared Neighborhood Hits	156
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

GAS6_HUMAN
NC score	0.186089 (rank : 179)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	291	Target Neighborhood Hits	348	Shared Neighborhood Hits	153
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

NET4_HUMAN
NC score	0.186067 (rank : 180)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	291	Target Neighborhood Hits	191	Shared Neighborhood Hits	108
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

ITB7_MOUSE
NC score	0.186050 (rank : 181)	θ value	0.00228821 (rank : 92)
Query Neighborhood Hits	291	Target Neighborhood Hits	277	Shared Neighborhood Hits	144
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

VWF_MOUSE
NC score	0.185535 (rank : 182)	θ value	4.1701e-05 (rank : 56)
Query Neighborhood Hits	291	Target Neighborhood Hits	381	Shared Neighborhood Hits	152
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_HUMAN
NC score	0.184600 (rank : 183)	θ value	0.00175202 (rank : 90)
Query Neighborhood Hits	291	Target Neighborhood Hits	396	Shared Neighborhood Hits	156
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

GAS6_MOUSE
NC score	0.184482 (rank : 184)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	291	Target Neighborhood Hits	343	Shared Neighborhood Hits	153
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ITB2_MOUSE
NC score	0.184237 (rank : 185)	θ value	0.47712 (rank : 179)
Query Neighborhood Hits	291	Target Neighborhood Hits	326	Shared Neighborhood Hits	157
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_MOUSE
NC score	0.183537 (rank : 186)	θ value	0.00390308 (rank : 98)
Query Neighborhood Hits	291	Target Neighborhood Hits	319	Shared Neighborhood Hits	162
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

PGBM_MOUSE
NC score	0.183508 (rank : 187)	θ value	6.43352e-06 (rank : 45)
Query Neighborhood Hits	291	Target Neighborhood Hits	1073	Shared Neighborhood Hits	201
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MATN3_MOUSE
NC score	0.183250 (rank : 188)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	291	Target Neighborhood Hits	261	Shared Neighborhood Hits	128
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
NC score	0.182790 (rank : 189)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	291	Target Neighborhood Hits	287	Shared Neighborhood Hits	133
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

NAGPA_MOUSE
NC score	0.182323 (rank : 190)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	291	Target Neighborhood Hits	308	Shared Neighborhood Hits	138
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

KR101_HUMAN
NC score	0.179295 (rank : 191)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	291	Target Neighborhood Hits	261	Shared Neighborhood Hits	120
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

ATRN_HUMAN
NC score	0.179147 (rank : 192)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	291	Target Neighborhood Hits	525	Shared Neighborhood Hits	153
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ITB6_MOUSE
NC score	0.178798 (rank : 193)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	291	Target Neighborhood Hits	341	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB1_MOUSE
NC score	0.177081 (rank : 194)	θ value	0.0431538 (rank : 136)
Query Neighborhood Hits	291	Target Neighborhood Hits	283	Shared Neighborhood Hits	151
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

COMP_HUMAN
NC score	0.176570 (rank : 195)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	291	Target Neighborhood Hits	258	Shared Neighborhood Hits	141
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
NC score	0.176283 (rank : 196)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	291	Target Neighborhood Hits	290	Shared Neighborhood Hits	152
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

PGBM_HUMAN
NC score	0.175784 (rank : 197)	θ value	0.000270298 (rank : 63)
Query Neighborhood Hits	291	Target Neighborhood Hits	1113	Shared Neighborhood Hits	194
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ITB1_HUMAN
NC score	0.175226 (rank : 198)	θ value	0.00665767 (rank : 107)
Query Neighborhood Hits	291	Target Neighborhood Hits	298	Shared Neighborhood Hits	152
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

TNR16_HUMAN
NC score	0.174465 (rank : 199)	θ value	1.81305 (rank : 219)
Query Neighborhood Hits	291	Target Neighborhood Hits	183	Shared Neighborhood Hits	101
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TSP4_MOUSE
NC score	0.173473 (rank : 200)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	291	Target Neighborhood Hits	276	Shared Neighborhood Hits	147
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

EGFL7_HUMAN
NC score	0.172033 (rank : 201)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	291	Target Neighborhood Hits	325	Shared Neighborhood Hits	147
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

LDLR_HUMAN
NC score	0.172016 (rank : 202)	θ value	4.03905 (rank : 245)
Query Neighborhood Hits	291	Target Neighborhood Hits	375	Shared Neighborhood Hits	159
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

TNR16_MOUSE
NC score	0.171766 (rank : 203)	θ value	0.0961366 (rank : 152)
Query Neighborhood Hits	291	Target Neighborhood Hits	178	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

ITB2_HUMAN
NC score	0.171441 (rank : 204)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	291	Target Neighborhood Hits	282	Shared Neighborhood Hits	152
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

NET1_HUMAN
NC score	0.170902 (rank : 205)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	291	Target Neighborhood Hits	149	Shared Neighborhood Hits	90
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

GRN_HUMAN
NC score	0.169931 (rank : 206)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	291	Target Neighborhood Hits	268	Shared Neighborhood Hits	123
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

ITB6_HUMAN
NC score	0.169891 (rank : 207)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	291	Target Neighborhood Hits	318	Shared Neighborhood Hits	155
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

TNR25_HUMAN
NC score	0.169665 (rank : 208)	θ value	0.0431538 (rank : 139)
Query Neighborhood Hits	291	Target Neighborhood Hits	172	Shared Neighborhood Hits	86
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

GRN_MOUSE
NC score	0.169267 (rank : 209)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	291	Target Neighborhood Hits	248	Shared Neighborhood Hits	121
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

MT3_MOUSE
NC score	0.168868 (rank : 210)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	291	Target Neighborhood Hits	68	Shared Neighborhood Hits	47
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

NET1_MOUSE
NC score	0.168471 (rank : 211)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	291	Target Neighborhood Hits	151	Shared Neighborhood Hits	88
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

TSP4_HUMAN
NC score	0.167520 (rank : 212)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	291	Target Neighborhood Hits	277	Shared Neighborhood Hits	145
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

BMPER_MOUSE
NC score	0.166624 (rank : 213)	θ value	0.00869519 (rank : 110)
Query Neighborhood Hits	291	Target Neighborhood Hits	194	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

LDLR_MOUSE
NC score	0.165987 (rank : 214)	θ value	0.62314 (rank : 183)
Query Neighborhood Hits	291	Target Neighborhood Hits	382	Shared Neighborhood Hits	156
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

TSP1_HUMAN
NC score	0.165699 (rank : 215)	θ value	0.00228821 (rank : 96)
Query Neighborhood Hits	291	Target Neighborhood Hits	389	Shared Neighborhood Hits	162
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

EMR1_HUMAN
NC score	0.165043 (rank : 216)	θ value	2.36792 (rank : 223)
Query Neighborhood Hits	291	Target Neighborhood Hits	382	Shared Neighborhood Hits	145
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

TSP1_MOUSE
NC score	0.164094 (rank : 217)	θ value	0.00390308 (rank : 102)
Query Neighborhood Hits	291	Target Neighborhood Hits	396	Shared Neighborhood Hits	164
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

KR108_HUMAN
NC score	0.162555 (rank : 218)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	291	Target Neighborhood Hits	226	Shared Neighborhood Hits	102
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LRP8_MOUSE
NC score	0.162213 (rank : 219)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	291	Target Neighborhood Hits	385	Shared Neighborhood Hits	155
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

TSP3_MOUSE
NC score	0.162135 (rank : 220)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	291	Target Neighborhood Hits	247	Shared Neighborhood Hits	140
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

EGFL7_MOUSE
NC score	0.161687 (rank : 221)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	291	Target Neighborhood Hits	287	Shared Neighborhood Hits	130
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

SUSD1_HUMAN
NC score	0.160795 (rank : 222)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	291	Target Neighborhood Hits	285	Shared Neighborhood Hits	119
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

VLDLR_HUMAN
NC score	0.160427 (rank : 223)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	291	Target Neighborhood Hits	383	Shared Neighborhood Hits	148
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
NC score	0.160177 (rank : 224)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	291	Target Neighborhood Hits	360	Shared Neighborhood Hits	146
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

TSP3_HUMAN
NC score	0.160172 (rank : 225)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	291	Target Neighborhood Hits	250	Shared Neighborhood Hits	133
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

BMPER_HUMAN
NC score	0.159084 (rank : 226)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	291	Target Neighborhood Hits	175	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

TNR9_MOUSE
NC score	0.157977 (rank : 227)	θ value	0.00390308 (rank : 100)
Query Neighborhood Hits	291	Target Neighborhood Hits	137	Shared Neighborhood Hits	82
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

CD248_HUMAN
NC score	0.157108 (rank : 228)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	291	Target Neighborhood Hits	679	Shared Neighborhood Hits	132
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
NC score	0.156610 (rank : 229)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	291	Target Neighborhood Hits	578	Shared Neighborhood Hits	128
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

ITB4_HUMAN
NC score	0.156557 (rank : 230)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	291	Target Neighborhood Hits	458	Shared Neighborhood Hits	150
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KR10B_HUMAN
NC score	0.156443 (rank : 231)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	291	Target Neighborhood Hits	269	Shared Neighborhood Hits	115
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

ITB8_HUMAN
NC score	0.156176 (rank : 232)	θ value	0.279714 (rank : 170)
Query Neighborhood Hits	291	Target Neighborhood Hits	280	Shared Neighborhood Hits	148
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KRA45_HUMAN
NC score	0.155451 (rank : 233)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	291	Target Neighborhood Hits	194	Shared Neighborhood Hits	86
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

LRP4_HUMAN
NC score	0.154199 (rank : 234)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	291	Target Neighborhood Hits	355	Shared Neighborhood Hits	147
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

KR105_HUMAN
NC score	0.153851 (rank : 235)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	291	Target Neighborhood Hits	271	Shared Neighborhood Hits	111
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KRA93_HUMAN
NC score	0.153368 (rank : 236)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	291	Target Neighborhood Hits	203	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

HMCN1_HUMAN
NC score	0.153246 (rank : 237)	θ value	5.44631e-05 (rank : 57)
Query Neighborhood Hits	291	Target Neighborhood Hits	983	Shared Neighborhood Hits	181
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

EMR2_HUMAN
NC score	0.152054 (rank : 238)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	291	Target Neighborhood Hits	345	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

CD97_HUMAN
NC score	0.151496 (rank : 239)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	291	Target Neighborhood Hits	353	Shared Neighborhood Hits	136
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

EMR1_MOUSE
NC score	0.151324 (rank : 240)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	291	Target Neighborhood Hits	349	Shared Neighborhood Hits	134
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

LRP4_MOUSE
NC score	0.151311 (rank : 241)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	291	Target Neighborhood Hits	351	Shared Neighborhood Hits	145
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

EGFL8_HUMAN
NC score	0.151108 (rank : 242)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	291	Target Neighborhood Hits	270	Shared Neighborhood Hits	116
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

LRP8_HUMAN
NC score	0.151039 (rank : 243)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	291	Target Neighborhood Hits	346	Shared Neighborhood Hits	138
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SLIT1_MOUSE
NC score	0.149510 (rank : 244)	θ value	0.813845 (rank : 196)
Query Neighborhood Hits	291	Target Neighborhood Hits	715	Shared Neighborhood Hits	164
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

KRA47_HUMAN
NC score	0.148797 (rank : 245)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	291	Target Neighborhood Hits	204	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

SLIT1_HUMAN
NC score	0.148485 (rank : 246)	θ value	5.27518 (rank : 257)
Query Neighborhood Hits	291	Target Neighborhood Hits	700	Shared Neighborhood Hits	163
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

EGFL8_MOUSE
NC score	0.147986 (rank : 247)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	291	Target Neighborhood Hits	266	Shared Neighborhood Hits	120
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

TNR23_MOUSE
NC score	0.147510 (rank : 248)	θ value	6.88961 (rank : 275)
Query Neighborhood Hits	291	Target Neighborhood Hits	114	Shared Neighborhood Hits	76
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

KRA98_HUMAN
NC score	0.147468 (rank : 249)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	291	Target Neighborhood Hits	185	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA92_HUMAN
NC score	0.147228 (rank : 250)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	291	Target Neighborhood Hits	198	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

MUC5B_HUMAN
NC score	0.145557 (rank : 251)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	291	Target Neighborhood Hits	1020	Shared Neighborhood Hits	158
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MT3_HUMAN
NC score	0.145279 (rank : 252)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	291	Target Neighborhood Hits	82	Shared Neighborhood Hits	53
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

KR102_HUMAN
NC score	0.144938 (rank : 253)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	291	Target Neighborhood Hits	264	Shared Neighborhood Hits	115
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR109_HUMAN
NC score	0.144237 (rank : 254)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	291	Target Neighborhood Hits	226	Shared Neighborhood Hits	97
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

SLIT2_HUMAN
NC score	0.141845 (rank : 255)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	291	Target Neighborhood Hits	708	Shared Neighborhood Hits	163
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TSP2_MOUSE
NC score	0.141722 (rank : 256)	θ value	1.81305 (rank : 220)
Query Neighborhood Hits	291	Target Neighborhood Hits	352	Shared Neighborhood Hits	147
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TECTA_MOUSE
NC score	0.141445 (rank : 257)	θ value	0.00665767 (rank : 109)
Query Neighborhood Hits	291	Target Neighborhood Hits	244	Shared Neighborhood Hits	121
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TNR14_HUMAN
NC score	0.141433 (rank : 258)	θ value	1.38821 (rank : 214)
Query Neighborhood Hits	291	Target Neighborhood Hits	149	Shared Neighborhood Hits	94
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

SORL_MOUSE
NC score	0.141067 (rank : 259)	θ value	0.62314 (rank : 185)
Query Neighborhood Hits	291	Target Neighborhood Hits	439	Shared Neighborhood Hits	152
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SLIT2_MOUSE
NC score	0.140156 (rank : 260)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	291	Target Neighborhood Hits	684	Shared Neighborhood Hits	153
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT3_MOUSE
NC score	0.139883 (rank : 261)	θ value	3.0926 (rank : 241)
Query Neighborhood Hits	291	Target Neighborhood Hits	700	Shared Neighborhood Hits	163
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SLIT3_HUMAN
NC score	0.139828 (rank : 262)	θ value	5.27518 (rank : 258)
Query Neighborhood Hits	291	Target Neighborhood Hits	682	Shared Neighborhood Hits	161
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

TNR9_HUMAN
NC score	0.139699 (rank : 263)	θ value	0.00228821 (rank : 95)
Query Neighborhood Hits	291	Target Neighborhood Hits	166	Shared Neighborhood Hits	97
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

HHIP_HUMAN
NC score	0.138571 (rank : 264)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	291	Target Neighborhood Hits	249	Shared Neighborhood Hits	117
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

TNR1A_MOUSE
NC score	0.137547 (rank : 265)	θ value	0.00134147 (rank : 88)
Query Neighborhood Hits	291	Target Neighborhood Hits	131	Shared Neighborhood Hits	66
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR26_MOUSE
NC score	0.137255 (rank : 266)	θ value	0.0961366 (rank : 153)
Query Neighborhood Hits	291	Target Neighborhood Hits	106	Shared Neighborhood Hits	72
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

SORL_HUMAN
NC score	0.137054 (rank : 267)	θ value	0.0563607 (rank : 146)
Query Neighborhood Hits	291	Target Neighborhood Hits	440	Shared Neighborhood Hits	148
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TSP2_HUMAN
NC score	0.136568 (rank : 268)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	291	Target Neighborhood Hits	359	Shared Neighborhood Hits	148
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

LCE1C_HUMAN
NC score	0.136395 (rank : 269)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	291	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

HHIP_MOUSE
NC score	0.136318 (rank : 270)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	291	Target Neighborhood Hits	219	Shared Neighborhood Hits	108
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

TNR4_MOUSE
NC score	0.135570 (rank : 271)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	291	Target Neighborhood Hits	137	Shared Neighborhood Hits	85
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

NFX1_HUMAN
NC score	0.134635 (rank : 272)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	291	Target Neighborhood Hits	405	Shared Neighborhood Hits	109
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

TNR7_HUMAN
NC score	0.133679 (rank : 273)	θ value	5.27518 (rank : 259)
Query Neighborhood Hits	291	Target Neighborhood Hits	120	Shared Neighborhood Hits	86
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

KRA94_HUMAN
NC score	0.130585 (rank : 274)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	291	Target Neighborhood Hits	204	Shared Neighborhood Hits	95
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

ZAN_HUMAN
NC score	0.130379 (rank : 275)	θ value	6.88961 (rank : 277)
Query Neighborhood Hits	291	Target Neighborhood Hits	679	Shared Neighborhood Hits	161
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

TECTA_HUMAN
NC score	0.129963 (rank : 276)	θ value	0.0736092 (rank : 149)
Query Neighborhood Hits	291	Target Neighborhood Hits	239	Shared Neighborhood Hits	112
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

MT2_MOUSE
NC score	0.128035 (rank : 277)	θ value	2.36792 (rank : 231)
Query Neighborhood Hits	291	Target Neighborhood Hits	81	Shared Neighborhood Hits	48
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

KR10C_HUMAN
NC score	0.127855 (rank : 278)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	291	Target Neighborhood Hits	219	Shared Neighborhood Hits	102
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KRA13_HUMAN
NC score	0.127749 (rank : 279)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	291	Target Neighborhood Hits	144	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

LCE1B_HUMAN
NC score	0.127264 (rank : 280)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	291	Target Neighborhood Hits	58	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE2A_HUMAN
NC score	0.127170 (rank : 281)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	291	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

EDIL3_MOUSE
NC score	0.125978 (rank : 282)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	291	Target Neighborhood Hits	317	Shared Neighborhood Hits	136
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

KRA11_HUMAN
NC score	0.125569 (rank : 283)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	291	Target Neighborhood Hits	155	Shared Neighborhood Hits	63
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

TENR_HUMAN
NC score	0.125199 (rank : 284)	θ value	0.0736092 (rank : 150)
Query Neighborhood Hits	291	Target Neighborhood Hits	526	Shared Neighborhood Hits	157
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

KRA44_HUMAN
NC score	0.124786 (rank : 285)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	291	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA99_HUMAN
NC score	0.124469 (rank : 286)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	291	Target Neighborhood Hits	173	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

MT4_MOUSE
NC score	0.124189 (rank : 287)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	67
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

LCE2B_HUMAN
NC score	0.121942 (rank : 288)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	291	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

TNR22_MOUSE
NC score	0.121829 (rank : 289)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	291	Target Neighborhood Hits	97	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

CD97_MOUSE
NC score	0.120964 (rank : 290)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	291	Target Neighborhood Hits	295	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

EDIL3_HUMAN
NC score	0.120867 (rank : 291)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	291	Target Neighborhood Hits	292	Shared Neighborhood Hits	128
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

KR412_HUMAN
NC score	0.120827 (rank : 292)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	291	Target Neighborhood Hits	178	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

TENR_MOUSE
NC score	0.119511 (rank : 293)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	291	Target Neighborhood Hits	531	Shared Neighborhood Hits	154
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

LCE2D_HUMAN
NC score	0.118917 (rank : 294)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	291	Target Neighborhood Hits	50	Shared Neighborhood Hits	23
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

TNR3_HUMAN
NC score	0.118605 (rank : 295)	θ value	0.0252991 (rank : 133)
Query Neighborhood Hits	291	Target Neighborhood Hits	145	Shared Neighborhood Hits	64
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

ERBB3_HUMAN
NC score	0.117496 (rank : 296)	θ value	2.98157e-11 (rank : 16)
Query Neighborhood Hits	291	Target Neighborhood Hits	918	Shared Neighborhood Hits	84
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

LYAM3_MOUSE
NC score	0.116524 (rank : 297)	θ value	6.88961 (rank : 274)
Query Neighborhood Hits	291	Target Neighborhood Hits	390	Shared Neighborhood Hits	142
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TNR5_MOUSE
NC score	0.116205 (rank : 298)	θ value	0.813845 (rank : 199)
Query Neighborhood Hits	291	Target Neighborhood Hits	131	Shared Neighborhood Hits	84
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

LCE1F_HUMAN
NC score	0.115905 (rank : 299)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	291	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

ERBB3_MOUSE
NC score	0.115454 (rank : 300)	θ value	8.67504e-11 (rank : 18)
Query Neighborhood Hits	291	Target Neighborhood Hits	898	Shared Neighborhood Hits	76
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

TNR1A_HUMAN
NC score	0.115449 (rank : 301)	θ value	1.06291 (rank : 203)
Query Neighborhood Hits	291	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

LCE2C_HUMAN
NC score	0.115303 (rank : 302)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	291	Target Neighborhood Hits	53	Shared Neighborhood Hits	26
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LYAM2_MOUSE
NC score	0.114893 (rank : 303)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	291	Target Neighborhood Hits	420	Shared Neighborhood Hits	156
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ELTD1_MOUSE
NC score	0.114637 (rank : 304)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	291	Target Neighborhood Hits	288	Shared Neighborhood Hits	114
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

MT1A_HUMAN
NC score	0.113832 (rank : 305)	θ value	3.0926 (rank : 236)
Query Neighborhood Hits	291	Target Neighborhood Hits	74	Shared Neighborhood Hits	46
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

LCE1E_HUMAN
NC score	0.113013 (rank : 306)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	291	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

TNR4_HUMAN
NC score	0.112737 (rank : 307)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	291	Target Neighborhood Hits	152	Shared Neighborhood Hits	76
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TIE1_HUMAN
NC score	0.112678 (rank : 308)	θ value	0.0252991 (rank : 132)
Query Neighborhood Hits	291	Target Neighborhood Hits	1241	Shared Neighborhood Hits	165
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MT4_HUMAN
NC score	0.112677 (rank : 309)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	291	Target Neighborhood Hits	83	Shared Neighborhood Hits	54
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

ZNFX1_HUMAN
NC score	0.112174 (rank : 310)	θ value	0.0563607 (rank : 147)
Query Neighborhood Hits	291	Target Neighborhood Hits	308	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

MT1X_HUMAN
NC score	0.111601 (rank : 311)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	291	Target Neighborhood Hits	76	Shared Neighborhood Hits	53
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

PROZ_MOUSE
NC score	0.111487 (rank : 312)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	291	Target Neighborhood Hits	410	Shared Neighborhood Hits	129
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_HUMAN
NC score	0.110748 (rank : 313)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	291	Target Neighborhood Hits	422	Shared Neighborhood Hits	130
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

TNR1B_MOUSE
NC score	0.109989 (rank : 314)	θ value	1.06291 (rank : 204)
Query Neighborhood Hits	291	Target Neighborhood Hits	123	Shared Neighborhood Hits	56
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

ZNFX1_MOUSE
NC score	0.109915 (rank : 315)	θ value	1.81305 (rank : 221)
Query Neighborhood Hits	291	Target Neighborhood Hits	407	Shared Neighborhood Hits	81
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

MT1_MOUSE
NC score	0.109694 (rank : 316)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	291	Target Neighborhood Hits	72	Shared Neighborhood Hits	46
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

TNR6_MOUSE
NC score	0.109574 (rank : 317)	θ value	0.125558 (rank : 159)
Query Neighborhood Hits	291	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

KR414_HUMAN
NC score	0.109208 (rank : 318)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	291	Target Neighborhood Hits	199	Shared Neighborhood Hits	87
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

MT1L_HUMAN
NC score	0.108997 (rank : 319)	θ value	3.0926 (rank : 239)
Query Neighborhood Hits	291	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

TNR1B_HUMAN
NC score	0.108682 (rank : 320)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	291	Target Neighborhood Hits	127	Shared Neighborhood Hits	67
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TIE1_MOUSE
NC score	0.108160 (rank : 321)	θ value	0.0148317 (rank : 123)
Query Neighborhood Hits	291	Target Neighborhood Hits	1266	Shared Neighborhood Hits	165
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MT1H_HUMAN
NC score	0.108159 (rank : 322)	θ value	1.81305 (rank : 217)
Query Neighborhood Hits	291	Target Neighborhood Hits	78	Shared Neighborhood Hits	51
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

LYAM2_HUMAN
NC score	0.108151 (rank : 323)	θ value	0.21417 (rank : 166)
Query Neighborhood Hits	291	Target Neighborhood Hits	394	Shared Neighborhood Hits	146
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

TNR3_MOUSE
NC score	0.106308 (rank : 324)	θ value	1.38821 (rank : 215)
Query Neighborhood Hits	291	Target Neighborhood Hits	113	Shared Neighborhood Hits	72
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

KRA15_HUMAN
NC score	0.106271 (rank : 325)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	291	Target Neighborhood Hits	126	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

TIE2_MOUSE
NC score	0.105750 (rank : 326)	θ value	0.00134147 (rank : 87)
Query Neighborhood Hits	291	Target Neighborhood Hits	1204	Shared Neighborhood Hits	171
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

ERBB4_HUMAN
NC score	0.105620 (rank : 327)	θ value	1.63604e-09 (rank : 20)
Query Neighborhood Hits	291	Target Neighborhood Hits	910	Shared Neighborhood Hits	75
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

CT127_HUMAN
NC score	0.105148 (rank : 328)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	291	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

TNR7_MOUSE
NC score	0.104832 (rank : 329)	θ value	5.27518 (rank : 260)
Query Neighborhood Hits	291	Target Neighborhood Hits	112	Shared Neighborhood Hits	68
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

MUC2_HUMAN
NC score	0.103520 (rank : 330)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	291	Target Neighborhood Hits	906	Shared Neighborhood Hits	120
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

KR103_HUMAN
NC score	0.103208 (rank : 331)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	291	Target Neighborhood Hits	212	Shared Neighborhood Hits	85
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

ERBB2_MOUSE
NC score	0.102964 (rank : 332)	θ value	5.62301e-10 (rank : 19)
Query Neighborhood Hits	291	Target Neighborhood Hits	918	Shared Neighborhood Hits	68
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB2_HUMAN
NC score	0.102525 (rank : 333)	θ value	1.80886e-08 (rank : 23)
Query Neighborhood Hits	291	Target Neighborhood Hits	1073	Shared Neighborhood Hits	68
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

LYAM3_HUMAN
NC score	0.102207 (rank : 334)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	291	Target Neighborhood Hits	378	Shared Neighborhood Hits	141
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

TNR6_HUMAN
NC score	0.101916 (rank : 335)	θ value	0.21417 (rank : 168)
Query Neighborhood Hits	291	Target Neighborhood Hits	95	Shared Neighborhood Hits	62
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

KR10A_HUMAN
NC score	0.101435 (rank : 336)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	291	Target Neighborhood Hits	232	Shared Neighborhood Hits	106
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

TENN_MOUSE
NC score	0.101269 (rank : 337)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	291	Target Neighborhood Hits	484	Shared Neighborhood Hits	147
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

LCE5A_HUMAN
NC score	0.101063 (rank : 338)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	291	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

EGFR_MOUSE
NC score	0.100859 (rank : 339)	θ value	3.41135e-07 (rank : 35)
Query Neighborhood Hits	291	Target Neighborhood Hits	927	Shared Neighborhood Hits	92
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

CSPG3_MOUSE
NC score	0.100619 (rank : 340)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	291	Target Neighborhood Hits	657	Shared Neighborhood Hits	142
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

TR10A_HUMAN
NC score	0.100070 (rank : 341)	θ value	0.0431538 (rank : 140)
Query Neighborhood Hits	291	Target Neighborhood Hits	82	Shared Neighborhood Hits	47
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

LCE1A_HUMAN
NC score	0.100051 (rank : 342)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	291	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

MT1G_HUMAN
NC score	0.099898 (rank : 343)	θ value	3.0926 (rank : 237)
Query Neighborhood Hits	291	Target Neighborhood Hits	63	Shared Neighborhood Hits	40
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

CSPG2_MOUSE
NC score	0.099455 (rank : 344)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	291	Target Neighborhood Hits	711	Shared Neighborhood Hits	140
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

EGFR_HUMAN
NC score	0.099278 (rank : 345)	θ value	2.61198e-07 (rank : 34)
Query Neighborhood Hits	291	Target Neighborhood Hits	939	Shared Neighborhood Hits	86
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

TR11B_HUMAN
NC score	0.099158 (rank : 346)	θ value	1.38821 (rank : 216)
Query Neighborhood Hits	291	Target Neighborhood Hits	92	Shared Neighborhood Hits	57
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

LCE1D_HUMAN
NC score	0.099031 (rank : 347)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	291	Target Neighborhood Hits	44	Shared Neighborhood Hits	26
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

CELR2_HUMAN
NC score	0.098500 (rank : 348)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	291	Target Neighborhood Hits	657	Shared Neighborhood Hits	170
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CFC1_HUMAN
NC score	0.097845 (rank : 349)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	291	Target Neighborhood Hits	148	Shared Neighborhood Hits	80
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

TNR8_HUMAN
NC score	0.097719 (rank : 350)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	291	Target Neighborhood Hits	198	Shared Neighborhood Hits	75
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TIE2_HUMAN
NC score	0.097642 (rank : 351)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	291	Target Neighborhood Hits	1192	Shared Neighborhood Hits	164
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

CSPG2_HUMAN
NC score	0.097420 (rank : 352)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	291	Target Neighborhood Hits	681	Shared Neighborhood Hits	138
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

TNR11_HUMAN
NC score	0.096569 (rank : 353)	θ value	0.62314 (rank : 187)
Query Neighborhood Hits	291	Target Neighborhood Hits	135	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

INSRR_HUMAN
NC score	0.096416 (rank : 354)	θ value	1.69304e-06 (rank : 39)
Query Neighborhood Hits	291	Target Neighborhood Hits	950	Shared Neighborhood Hits	101
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LCE3A_HUMAN
NC score	0.095770 (rank : 355)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	291	Target Neighborhood Hits	29	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

INSRR_MOUSE
NC score	0.095549 (rank : 356)	θ value	6.43352e-06 (rank : 43)
Query Neighborhood Hits	291	Target Neighborhood Hits	961	Shared Neighborhood Hits	113
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

CSPG3_HUMAN
NC score	0.095453 (rank : 357)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	291	Target Neighborhood Hits	676	Shared Neighborhood Hits	140
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CRAC1_MOUSE
NC score	0.094904 (rank : 358)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	291	Target Neighborhood Hits	112	Shared Neighborhood Hits	63
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

TNR5_HUMAN
NC score	0.094772 (rank : 359)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	67
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

FATH_HUMAN
NC score	0.094365 (rank : 360)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	291	Target Neighborhood Hits	570	Shared Neighborhood Hits	156
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

IGF1R_MOUSE
NC score	0.094341 (rank : 361)	θ value	3.41135e-07 (rank : 36)
Query Neighborhood Hits	291	Target Neighborhood Hits	973	Shared Neighborhood Hits	95
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

TR10C_HUMAN
NC score	0.094307 (rank : 362)	θ value	0.279714 (rank : 172)
Query Neighborhood Hits	291	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

CELR3_HUMAN
NC score	0.093963 (rank : 363)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	291	Target Neighborhood Hits	680	Shared Neighborhood Hits	161
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
NC score	0.093937 (rank : 364)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	291	Target Neighborhood Hits	687	Shared Neighborhood Hits	162
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR1_MOUSE
NC score	0.093894 (rank : 365)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	291	Target Neighborhood Hits	617	Shared Neighborhood Hits	167
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CRAC1_HUMAN
NC score	0.093475 (rank : 366)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	291	Target Neighborhood Hits	111	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

MT1B_HUMAN
NC score	0.093253 (rank : 367)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	291	Target Neighborhood Hits	87	Shared Neighborhood Hits	54
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

TENN_HUMAN
NC score	0.093153 (rank : 368)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	291	Target Neighborhood Hits	453	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TNR6B_HUMAN
NC score	0.092717 (rank : 369)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	291	Target Neighborhood Hits	103	Shared Neighborhood Hits	65
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

CELR1_HUMAN
NC score	0.092620 (rank : 370)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	291	Target Neighborhood Hits	613	Shared Neighborhood Hits	157
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

TDGF1_MOUSE
NC score	0.092440 (rank : 371)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	291	Target Neighborhood Hits	146	Shared Neighborhood Hits	80
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

MKS3_MOUSE
NC score	0.092310 (rank : 372)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	291	Target Neighborhood Hits	89	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

IGF1R_HUMAN
NC score	0.091242 (rank : 373)	θ value	1.09739e-05 (rank : 47)
Query Neighborhood Hits	291	Target Neighborhood Hits	977	Shared Neighborhood Hits	90
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

CHRD_HUMAN
NC score	0.091187 (rank : 374)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

KR410_HUMAN
NC score	0.090613 (rank : 375)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	291	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

CELR2_MOUSE
NC score	0.090387 (rank : 376)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	291	Target Neighborhood Hits	584	Shared Neighborhood Hits	157
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

ESM1_HUMAN
NC score	0.089807 (rank : 377)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	291	Target Neighborhood Hits	110	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

TR10B_HUMAN
NC score	0.089743 (rank : 378)	θ value	1.06291 (rank : 205)
Query Neighborhood Hits	291	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

CHRD_MOUSE
NC score	0.089520 (rank : 379)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

INSR_HUMAN
NC score	0.088102 (rank : 380)	θ value	3.19293e-05 (rank : 51)
Query Neighborhood Hits	291	Target Neighborhood Hits	963	Shared Neighborhood Hits	90
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_MOUSE
NC score	0.087679 (rank : 381)	θ value	0.000121331 (rank : 60)
Query Neighborhood Hits	291	Target Neighborhood Hits	968	Shared Neighborhood Hits	79
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

TNR11_MOUSE
NC score	0.086857 (rank : 382)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	291	Target Neighborhood Hits	121	Shared Neighborhood Hits	73
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

MT1F_HUMAN
NC score	0.086693 (rank : 383)	θ value	4.03905 (rank : 247)
Query Neighborhood Hits	291	Target Neighborhood Hits	73	Shared Neighborhood Hits	45
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1E_HUMAN
NC score	0.086573 (rank : 384)	θ value	4.03905 (rank : 246)
Query Neighborhood Hits	291	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MATN1_MOUSE
NC score	0.085890 (rank : 385)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	291	Target Neighborhood Hits	186	Shared Neighborhood Hits	74
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MT2_HUMAN
NC score	0.085827 (rank : 386)	θ value	4.03905 (rank : 248)
Query Neighborhood Hits	291	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MBTP1_HUMAN
NC score	0.085314 (rank : 387)	θ value	0.813845 (rank : 194)
Query Neighborhood Hits	291	Target Neighborhood Hits	28	Shared Neighborhood Hits	11
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

BMP1_MOUSE
NC score	0.085253 (rank : 388)	θ value	0.813845 (rank : 190)
Query Neighborhood Hits	291	Target Neighborhood Hits	236	Shared Neighborhood Hits	93
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

MATN1_HUMAN
NC score	0.085041 (rank : 389)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	291	Target Neighborhood Hits	191	Shared Neighborhood Hits	78
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

BMP1_HUMAN
NC score	0.084901 (rank : 390)	θ value	0.813845 (rank : 189)
Query Neighborhood Hits	291	Target Neighborhood Hits	233	Shared Neighborhood Hits	93
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TR10D_HUMAN
NC score	0.084166 (rank : 391)	θ value	0.47712 (rank : 181)
Query Neighborhood Hits	291	Target Neighborhood Hits	62	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

ESM1_MOUSE
NC score	0.082772 (rank : 392)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	291	Target Neighborhood Hits	107	Shared Neighborhood Hits	55
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

TR10B_MOUSE
NC score	0.081726 (rank : 393)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	291	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

ELTD1_HUMAN
NC score	0.081646 (rank : 394)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	291	Target Neighborhood Hits	269	Shared Neighborhood Hits	106
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

MFGM_MOUSE
NC score	0.081361 (rank : 395)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	291	Target Neighborhood Hits	233	Shared Neighborhood Hits	102
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

TR11B_MOUSE
NC score	0.080658 (rank : 396)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	291	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TLL2_MOUSE
NC score	0.080607 (rank : 397)	θ value	1.06291 (rank : 202)
Query Neighborhood Hits	291	Target Neighborhood Hits	240	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

FA76B_MOUSE
NC score	0.080366 (rank : 398)	θ value	0.00665767 (rank : 105)
Query Neighborhood Hits	291	Target Neighborhood Hits	181	Shared Neighborhood Hits	13
SwissProt Accessions	Q80XP8, Q3UMA6, Q80YR1, Q8CI69	Gene names	Fam76b
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

MBTP1_MOUSE
NC score	0.080271 (rank : 399)	θ value	0.813845 (rank : 195)
Query Neighborhood Hits	291	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9WTZ2, Q6PG67	Gene names	Mbtps1, S1p, Ski1
Domain Architecture
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin isozyme 1) (SKI-1) (Sterol-regulated luminal protease).

TNR21_HUMAN
NC score	0.080223 (rank : 400)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	291	Target Neighborhood Hits	90	Shared Neighborhood Hits	58
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TLL1_MOUSE
NC score	0.078718 (rank : 401)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	291	Target Neighborhood Hits	237	Shared Neighborhood Hits	95
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TNR8_MOUSE
NC score	0.078532 (rank : 402)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	291	Target Neighborhood Hits	208	Shared Neighborhood Hits	77
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TLL1_HUMAN
NC score	0.078197 (rank : 403)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	291	Target Neighborhood Hits	236	Shared Neighborhood Hits	94
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

MT1I_HUMAN
NC score	0.076380 (rank : 404)	θ value	3.0926 (rank : 238)
Query Neighborhood Hits	291	Target Neighborhood Hits	64	Shared Neighborhood Hits	42
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

LRP6_HUMAN
NC score	0.076337 (rank : 405)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	291	Target Neighborhood Hits	235	Shared Neighborhood Hits	93
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

TLL2_HUMAN
NC score	0.075792 (rank : 406)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	291	Target Neighborhood Hits	241	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

VEGFC_HUMAN
NC score	0.075755 (rank : 407)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	291	Target Neighborhood Hits	128	Shared Neighborhood Hits	74
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

MUC13_MOUSE
NC score	0.075621 (rank : 408)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	291	Target Neighborhood Hits	447	Shared Neighborhood Hits	104
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PERT_HUMAN
NC score	0.075309 (rank : 409)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	291	Target Neighborhood Hits	221	Shared Neighborhood Hits	91
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

LYAM1_MOUSE
NC score	0.074719 (rank : 410)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	291	Target Neighborhood Hits	332	Shared Neighborhood Hits	114
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

CFC1_MOUSE
NC score	0.074504 (rank : 411)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	291	Target Neighborhood Hits	125	Shared Neighborhood Hits	67
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

LRP6_MOUSE
NC score	0.074440 (rank : 412)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	291	Target Neighborhood Hits	232	Shared Neighborhood Hits	91
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

MKS3_HUMAN
NC score	0.074184 (rank : 413)	θ value	1.38821 (rank : 210)
Query Neighborhood Hits	291	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

TNR19_MOUSE
NC score	0.074057 (rank : 414)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	291	Target Neighborhood Hits	100	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

RECK_MOUSE
NC score	0.073850 (rank : 415)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	291	Target Neighborhood Hits	158	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

RECK_HUMAN
NC score	0.073685 (rank : 416)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	291	Target Neighborhood Hits	189	Shared Neighborhood Hits	69
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TEFF2_MOUSE
NC score	0.073623 (rank : 417)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	291	Target Neighborhood Hits	214	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

KRA42_HUMAN
NC score	0.073548 (rank : 418)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	291	Target Neighborhood Hits	149	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

TDGF1_HUMAN
NC score	0.073303 (rank : 419)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	291	Target Neighborhood Hits	132	Shared Neighborhood Hits	69
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

PERT_MOUSE
NC score	0.072712 (rank : 420)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	291	Target Neighborhood Hits	221	Shared Neighborhood Hits	90
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

TDGF2_HUMAN
NC score	0.072544 (rank : 421)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	291	Target Neighborhood Hits	131	Shared Neighborhood Hits	68
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TEFF2_HUMAN
NC score	0.072045 (rank : 422)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	291	Target Neighborhood Hits	211	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

FREM2_MOUSE
NC score	0.071792 (rank : 423)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	291	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

LRP5_MOUSE
NC score	0.071636 (rank : 424)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	291	Target Neighborhood Hits	236	Shared Neighborhood Hits	89
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

FREM2_HUMAN
NC score	0.071310 (rank : 425)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	291	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

PHXR5_MOUSE
NC score	0.070685 (rank : 426)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

CRDL2_MOUSE
NC score	0.070578 (rank : 427)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	291	Target Neighborhood Hits	81	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

UROL1_MOUSE
NC score	0.069852 (rank : 428)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	291	Target Neighborhood Hits	235	Shared Neighborhood Hits	86
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

TNR21_MOUSE
NC score	0.069615 (rank : 429)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	291	Target Neighborhood Hits	108	Shared Neighborhood Hits	57
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

LRP5_HUMAN
NC score	0.069465 (rank : 430)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	291	Target Neighborhood Hits	224	Shared Neighborhood Hits	84
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

FST_MOUSE
NC score	0.068975 (rank : 431)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	291	Target Neighborhood Hits	146	Shared Neighborhood Hits	53
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

LYAM1_HUMAN
NC score	0.068585 (rank : 432)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	291	Target Neighborhood Hits	315	Shared Neighborhood Hits	113
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

CRDL2_HUMAN
NC score	0.067877 (rank : 433)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	291	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

LORI_MOUSE
NC score	0.067689 (rank : 434)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	291	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRP3_HUMAN
NC score	0.067478 (rank : 435)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	291	Target Neighborhood Hits	280	Shared Neighborhood Hits	80
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

CLC14_MOUSE
NC score	0.066805 (rank : 436)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	291	Target Neighborhood Hits	120	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

MCSP_MOUSE
NC score	0.065843 (rank : 437)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	291	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

LRP10_MOUSE
NC score	0.065764 (rank : 438)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	291	Target Neighborhood Hits	169	Shared Neighborhood Hits	65
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

TNR19_HUMAN
NC score	0.065277 (rank : 439)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	291	Target Neighborhood Hits	89	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

CSPG4_HUMAN
NC score	0.064786 (rank : 440)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	291	Target Neighborhood Hits	112	Shared Neighborhood Hits	17
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

UROL1_HUMAN
NC score	0.064689 (rank : 441)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	291	Target Neighborhood Hits	213	Shared Neighborhood Hits	81
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

SRCH_HUMAN
NC score	0.064294 (rank : 442)	θ value	0.125558 (rank : 158)
Query Neighborhood Hits	291	Target Neighborhood Hits	225	Shared Neighborhood Hits	26
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

VEGFC_MOUSE
NC score	0.064111 (rank : 443)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	291	Target Neighborhood Hits	119	Shared Neighborhood Hits	66
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

LRP10_HUMAN
NC score	0.064000 (rank : 444)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	291	Target Neighborhood Hits	197	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

FA76B_HUMAN
NC score	0.063746 (rank : 445)	θ value	0.00665767 (rank : 104)
Query Neighborhood Hits	291	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	Q5HYJ3, Q6PIU3, Q8TC53	Gene names	FAM76B
Domain Architecture	No domain graphic available
Description	Protein FAM76B.

CRDL1_HUMAN
NC score	0.063251 (rank : 446)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	291	Target Neighborhood Hits	75	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

PROP_MOUSE
NC score	0.063178 (rank : 447)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	291	Target Neighborhood Hits	165	Shared Neighborhood Hits	46
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

CRDL1_MOUSE
NC score	0.063104 (rank : 448)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	291	Target Neighborhood Hits	81	Shared Neighborhood Hits	23
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

FREM3_MOUSE
NC score	0.062863 (rank : 449)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	291	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

FREM3_HUMAN
NC score	0.062830 (rank : 450)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	291	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

HABP2_HUMAN
NC score	0.062822 (rank : 451)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	291	Target Neighborhood Hits	431	Shared Neighborhood Hits	127
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

FST_HUMAN
NC score	0.062448 (rank : 452)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	291	Target Neighborhood Hits	129	Shared Neighborhood Hits	44
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

CLC14_HUMAN
NC score	0.062408 (rank : 453)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	291	Target Neighborhood Hits	143	Shared Neighborhood Hits	68
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

HABP2_MOUSE
NC score	0.062052 (rank : 454)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	291	Target Neighborhood Hits	445	Shared Neighborhood Hits	127
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

KR413_HUMAN
NC score	0.061747 (rank : 455)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	291	Target Neighborhood Hits	112	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

LCE4A_HUMAN
NC score	0.061639 (rank : 456)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	291	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

CSPG4_MOUSE
NC score	0.061133 (rank : 457)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	291	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CO6_HUMAN
NC score	0.061032 (rank : 458)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	291	Target Neighborhood Hits	331	Shared Neighborhood Hits	107
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

ZN330_HUMAN
NC score	0.060782 (rank : 459)	θ value	0.47712 (rank : 182)
Query Neighborhood Hits	291	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

EMR3_HUMAN
NC score	0.058833 (rank : 460)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	291	Target Neighborhood Hits	245	Shared Neighborhood Hits	93
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

TR13B_MOUSE
NC score	0.058801 (rank : 461)	θ value	1.06291 (rank : 206)
Query Neighborhood Hits	291	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ET35, Q9DBZ3	Gene names	Tnfrsf13b, Taci
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor).

NRX1A_HUMAN
NC score	0.058327 (rank : 462)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	291	Target Neighborhood Hits	170	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
NC score	0.057698 (rank : 463)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	291	Target Neighborhood Hits	164	Shared Neighborhood Hits	63
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

FA10_MOUSE
NC score	0.057573 (rank : 464)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	291	Target Neighborhood Hits	435	Shared Neighborhood Hits	130
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FSTL3_HUMAN
NC score	0.056923 (rank : 465)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	291	Target Neighborhood Hits	162	Shared Neighborhood Hits	70
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FREM1_HUMAN
NC score	0.056565 (rank : 466)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	291	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

RELN_MOUSE
NC score	0.056450 (rank : 467)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	291	Target Neighborhood Hits	235	Shared Neighborhood Hits	96
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

SPON1_MOUSE
NC score	0.056257 (rank : 468)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	291	Target Neighborhood Hits	123	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

FA76A_MOUSE
NC score	0.056018 (rank : 469)	θ value	0.163984 (rank : 162)
Query Neighborhood Hits	291	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	Q922G2, Q3U3U8, Q3V3N2	Gene names	Fam76a
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

FA76A_HUMAN
NC score	0.055718 (rank : 470)	θ value	0.163984 (rank : 161)
Query Neighborhood Hits	291	Target Neighborhood Hits	149	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TAV0, O95565, O95566, Q8N7J5	Gene names	FAM76A
Domain Architecture	No domain graphic available
Description	Protein FAM76A.

EPHB4_HUMAN
NC score	0.055713 (rank : 471)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	291	Target Neighborhood Hits	1056	Shared Neighborhood Hits	129
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

MT1M_HUMAN
NC score	0.055433 (rank : 472)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	291	Target Neighborhood Hits	72	Shared Neighborhood Hits	44
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

NRX3A_HUMAN
NC score	0.055410 (rank : 473)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	291	Target Neighborhood Hits	164	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PCSK9_HUMAN
NC score	0.055223 (rank : 474)	θ value	4.03905 (rank : 249)
Query Neighborhood Hits	291	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NBP7, Q5PSM5	Gene names	PCSK9, NARC1
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 9 precursor (EC 3.4.21.-) (Proprotein convertase PC9) (Subtilisin/kexin-like protease PC9) (Neural apoptosis-regulated convertase 1) (NARC-1).

FREM1_MOUSE
NC score	0.055022 (rank : 475)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	291	Target Neighborhood Hits	163	Shared Neighborhood Hits	3
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FA10_HUMAN
NC score	0.054994 (rank : 476)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	291	Target Neighborhood Hits	431	Shared Neighborhood Hits	127
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

CORIN_HUMAN
NC score	0.054945 (rank : 477)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	291	Target Neighborhood Hits	453	Shared Neighborhood Hits	124
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

SPON1_HUMAN
NC score	0.054874 (rank : 478)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	291	Target Neighborhood Hits	117	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

RELN_HUMAN
NC score	0.054584 (rank : 479)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	291	Target Neighborhood Hits	233	Shared Neighborhood Hits	95
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

PROC_MOUSE
NC score	0.054555 (rank : 480)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	291	Target Neighborhood Hits	426	Shared Neighborhood Hits	126
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

WFDC3_HUMAN
NC score	0.054108 (rank : 481)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	291	Target Neighborhood Hits	138	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

PROP_HUMAN
NC score	0.053627 (rank : 482)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	291	Target Neighborhood Hits	126	Shared Neighborhood Hits	39
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

NRX2A_HUMAN
NC score	0.053144 (rank : 483)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	291	Target Neighborhood Hits	614	Shared Neighborhood Hits	67
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PAPPA_MOUSE
NC score	0.052932 (rank : 484)	θ value	0.365318 (rank : 176)
Query Neighborhood Hits	291	Target Neighborhood Hits	153	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

ASTN_HUMAN
NC score	0.052774 (rank : 485)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	291	Target Neighborhood Hits	105	Shared Neighborhood Hits	54
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

EPHA2_MOUSE
NC score	0.052640 (rank : 486)	θ value	3.0926 (rank : 234)
Query Neighborhood Hits	291	Target Neighborhood Hits	1020	Shared Neighborhood Hits	94
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHA1_HUMAN
NC score	0.052394 (rank : 487)	θ value	1.38821 (rank : 208)
Query Neighborhood Hits	291	Target Neighborhood Hits	997	Shared Neighborhood Hits	96
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

PAPPA_HUMAN
NC score	0.051841 (rank : 488)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	291	Target Neighborhood Hits	161	Shared Neighborhood Hits	51
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

EPHB6_HUMAN
NC score	0.051752 (rank : 489)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	291	Target Neighborhood Hits	912	Shared Neighborhood Hits	85
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

EPHAA_HUMAN
NC score	0.051706 (rank : 490)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	291	Target Neighborhood Hits	960	Shared Neighborhood Hits	65
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

ADA17_HUMAN
NC score	0.051604 (rank : 491)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	291	Target Neighborhood Hits	223	Shared Neighborhood Hits	87
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

EPHA1_MOUSE
NC score	0.051077 (rank : 492)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	291	Target Neighborhood Hits	958	Shared Neighborhood Hits	91
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA7_HUMAN
NC score	0.050796 (rank : 493)	θ value	2.36792 (rank : 224)
Query Neighborhood Hits	291	Target Neighborhood Hits	1053	Shared Neighborhood Hits	105
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

LRP12_HUMAN
NC score	0.050785 (rank : 494)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	291	Target Neighborhood Hits	205	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

PAP2_HUMAN
NC score	0.050669 (rank : 495)	θ value	0.125558 (rank : 157)
Query Neighborhood Hits	291	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

ASTN_MOUSE
NC score	0.050580 (rank : 496)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	291	Target Neighborhood Hits	98	Shared Neighborhood Hits	52
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

FA9_HUMAN
NC score	0.050553 (rank : 497)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	291	Target Neighborhood Hits	421	Shared Neighborhood Hits	118
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

KRA24_HUMAN
NC score	0.050516 (rank : 498)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	291	Target Neighborhood Hits	192	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

ADA19_MOUSE
NC score	0.050410 (rank : 499)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	291	Target Neighborhood Hits	315	Shared Neighborhood Hits	118
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

CORIN_MOUSE
NC score	0.050320 (rank : 500)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	291	Target Neighborhood Hits	451	Shared Neighborhood Hits	122
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ATS17_HUMAN
NC score	0.050300 (rank : 501)	θ value	0.0330416 (rank : 134)
Query Neighborhood Hits	291	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

TR13B_HUMAN
NC score	0.049940 (rank : 502)	θ value	6.88961 (rank : 276)
Query Neighborhood Hits	291	Target Neighborhood Hits	24	Shared Neighborhood Hits	9
SwissProt Accessions	O14836, Q7Z6F5	Gene names	TNFRSF13B, TACI
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 13B (Transmembrane activator and CAML interactor) (CD267 antigen).

THYG_HUMAN
NC score	0.046343 (rank : 503)	θ value	0.62314 (rank : 186)
Query Neighborhood Hits	291	Target Neighborhood Hits	154	Shared Neighborhood Hits	55
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

ATL3_HUMAN
NC score	0.046311 (rank : 504)	θ value	0.0252991 (rank : 127)
Query Neighborhood Hits	291	Target Neighborhood Hits	414	Shared Neighborhood Hits	40
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

EPHA4_MOUSE
NC score	0.043057 (rank : 505)	θ value	6.88961 (rank : 270)
Query Neighborhood Hits	291	Target Neighborhood Hits	982	Shared Neighborhood Hits	63
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

THYG_MOUSE
NC score	0.042786 (rank : 506)	θ value	1.38821 (rank : 213)
Query Neighborhood Hits	291	Target Neighborhood Hits	161	Shared Neighborhood Hits	61
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

EPHA4_HUMAN
NC score	0.041905 (rank : 507)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	291	Target Neighborhood Hits	975	Shared Neighborhood Hits	59
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

BAI3_MOUSE
NC score	0.041580 (rank : 508)	θ value	0.47712 (rank : 178)
Query Neighborhood Hits	291	Target Neighborhood Hits	250	Shared Neighborhood Hits	40
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_HUMAN
NC score	0.040585 (rank : 509)	θ value	1.38821 (rank : 207)
Query Neighborhood Hits	291	Target Neighborhood Hits	246	Shared Neighborhood Hits	39
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

EPHA8_MOUSE
NC score	0.039991 (rank : 510)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	291	Target Neighborhood Hits	969	Shared Neighborhood Hits	46
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

CILP1_HUMAN
NC score	0.039028 (rank : 511)	θ value	0.813845 (rank : 191)
Query Neighborhood Hits	291	Target Neighborhood Hits	266	Shared Neighborhood Hits	37
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

ADA22_MOUSE
NC score	0.038796 (rank : 512)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	291	Target Neighborhood Hits	225	Shared Neighborhood Hits	95
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ATS19_MOUSE
NC score	0.038098 (rank : 513)	θ value	0.0961366 (rank : 151)
Query Neighborhood Hits	291	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

CSMD1_MOUSE
NC score	0.036433 (rank : 514)	θ value	1.06291 (rank : 200)
Query Neighborhood Hits	291	Target Neighborhood Hits	193	Shared Neighborhood Hits	43
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

ADA22_HUMAN
NC score	0.035286 (rank : 515)	θ value	5.27518 (rank : 251)
Query Neighborhood Hits	291	Target Neighborhood Hits	211	Shared Neighborhood Hits	96
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

C1R_HUMAN
NC score	0.035112 (rank : 516)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	291	Target Neighborhood Hits	364	Shared Neighborhood Hits	85
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

ATS19_HUMAN
NC score	0.033819 (rank : 517)	θ value	0.47712 (rank : 177)
Query Neighborhood Hits	291	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q8TE59	Gene names	ADAMTS19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

CSMD1_HUMAN
NC score	0.033064 (rank : 518)	θ value	5.27518 (rank : 252)
Query Neighborhood Hits	291	Target Neighborhood Hits	176	Shared Neighborhood Hits	34
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

FAM5B_MOUSE
NC score	0.030982 (rank : 519)	θ value	5.27518 (rank : 254)
Query Neighborhood Hits	291	Target Neighborhood Hits	51	Shared Neighborhood Hits	27
SwissProt Accessions	Q6DFY8, Q80T96	Gene names	Fam5b, Kiaa1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor.

ATS16_HUMAN
NC score	0.030181 (rank : 520)	θ value	3.0926 (rank : 233)
Query Neighborhood Hits	291	Target Neighborhood Hits	208	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

FAM5B_HUMAN
NC score	0.027542 (rank : 521)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	291	Target Neighborhood Hits	55	Shared Neighborhood Hits	28
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

PHF7_HUMAN
NC score	0.027167 (rank : 522)	θ value	3.0926 (rank : 240)
Query Neighborhood Hits	291	Target Neighborhood Hits	71	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

ATS18_HUMAN
NC score	0.026815 (rank : 523)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	291	Target Neighborhood Hits	169	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS18_MOUSE
NC score	0.024115 (rank : 524)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	291	Target Neighborhood Hits	163	Shared Neighborhood Hits	27
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

FAM5C_MOUSE
NC score	0.023449 (rank : 525)	θ value	2.36792 (rank : 226)
Query Neighborhood Hits	291	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q499E0, Q8K0R9	Gene names	Fam5c
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor.

FAM5C_HUMAN
NC score	0.023404 (rank : 526)	θ value	2.36792 (rank : 225)
Query Neighborhood Hits	291	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q76B58, O95726	Gene names	FAM5C, DBCCR1L, DBCCR1L1
Domain Architecture	No domain graphic available
Description	Protein FAM5C precursor (DBCCR1-like protein 1).

VEGFD_HUMAN
NC score	0.022507 (rank : 527)	θ value	0.62314 (rank : 188)
Query Neighborhood Hits	291	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

RNF37_MOUSE
NC score	0.020663 (rank : 528)	θ value	1.38821 (rank : 212)
Query Neighborhood Hits	291	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q925F4	Gene names	Ubox5, Rnf37, Ubce7ip5, Uip5
Domain Architecture
Description	RING finger protein 37 (Ubiquitin-conjugating enzyme 7-interacting protein 5) (UbcM4-interacting protein 5) (U-box domain-containing protein 5).

TMPS7_MOUSE
NC score	0.016679 (rank : 529)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	291	Target Neighborhood Hits	275	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

FHR4_HUMAN
NC score	0.014101 (rank : 530)	θ value	6.88961 (rank : 272)
Query Neighborhood Hits	291	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

PARC_HUMAN
NC score	0.009853 (rank : 531)	θ value	1.38821 (rank : 211)
Query Neighborhood Hits	291	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

V2R1B_MOUSE
NC score	0.005943 (rank : 532)	θ value	5.27518 (rank : 261)
Query Neighborhood Hits	291	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

COLQ_HUMAN
NC score	0.004561 (rank : 533)	θ value	4.03905 (rank : 243)
Query Neighborhood Hits	291	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

FBXL2_MOUSE
NC score	0.002387 (rank : 534)	θ value	6.88961 (rank : 271)
Query Neighborhood Hits	291	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BH16, Q8BXM4	Gene names	Fbxl2, Fbl2
Domain Architecture
Description	F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2).

HFE_HUMAN
NC score	-0.002312 (rank : 535)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	291	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q30201, O75929, O75930, O75931, Q96KU5, Q96KU7, Q96KU8, Q9HC64, Q9HC68, Q9HC70, Q9HC83	Gene names	HFE, HLAH
Domain Architecture
Description	Hereditary hemochromatosis protein precursor (HLA-H).

1A25_HUMAN
NC score	-0.002504 (rank : 536)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	291	Target Neighborhood Hits	202	Shared Neighborhood Hits	3
SwissProt Accessions	P18462, Q95362, Q9TQE8, Q9TQG0, Q9UQU3	Gene names	HLA-A, HLAA
Domain Architecture
Description	HLA class I histocompatibility antigen, A-25 alpha chain precursor (MHC class I antigen A*25) (A-10).

ZN611_HUMAN
NC score	-0.003126 (rank : 537)	θ value	5.27518 (rank : 262)
Query Neighborhood Hits	291	Target Neighborhood Hits	769	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N823, Q69YG9	Gene names	ZNF611
Domain Architecture	No domain graphic available
Description	Zinc finger protein 611.

ZN429_HUMAN
NC score	-0.004219 (rank : 538)	θ value	0.279714 (rank : 174)
Query Neighborhood Hits	291	Target Neighborhood Hits	766	Shared Neighborhood Hits	11
SwissProt Accessions	Q86V71	Gene names	ZNF429
Domain Architecture
Description	Zinc finger protein 429.

ZN208_HUMAN
NC score	-0.004708 (rank : 539)	θ value	4.03905 (rank : 250)
Query Neighborhood Hits	291	Target Neighborhood Hits	771	Shared Neighborhood Hits	13
SwissProt Accessions	O43345	Gene names	ZNF208, ZNF91L
Domain Architecture
Description	Zinc finger protein 208.

ZN679_HUMAN
NC score	-0.005726 (rank : 540)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	291	Target Neighborhood Hits	746	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYX0	Gene names	ZNF679
Domain Architecture	No domain graphic available
Description	Zinc finger protein 679.