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Network neighborhood for query Sequence : TNR1B_MOUSE

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TNR1B_MOUSE
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TNR1B_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	123	Target Neighborhood Hits	123	Shared Neighborhood Hits	123
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR1B_HUMAN
θ value	3.87392e-144 (rank : 2)	NC score	0.967517 (rank : 2)
Query Neighborhood Hits	123	Target Neighborhood Hits	127	Shared Neighborhood Hits	64
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TR11B_HUMAN
θ value	2.42779e-29 (rank : 3)	NC score	0.859525 (rank : 4)
Query Neighborhood Hits	123	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR6B_HUMAN
θ value	6.61148e-27 (rank : 4)	NC score	0.873760 (rank : 3)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	58
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TR11B_MOUSE
θ value	2.51237e-26 (rank : 5)	NC score	0.848563 (rank : 5)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	54
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR3_HUMAN
θ value	3.62785e-25 (rank : 6)	NC score	0.839048 (rank : 6)
Query Neighborhood Hits	123	Target Neighborhood Hits	145	Shared Neighborhood Hits	60
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR21_MOUSE
θ value	3.39556e-23 (rank : 7)	NC score	0.782962 (rank : 14)
Query Neighborhood Hits	123	Target Neighborhood Hits	108	Shared Neighborhood Hits	51
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR11_HUMAN
θ value	9.87957e-23 (rank : 8)	NC score	0.789072 (rank : 12)
Query Neighborhood Hits	123	Target Neighborhood Hits	135	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR3_MOUSE
θ value	1.6852e-22 (rank : 9)	NC score	0.826780 (rank : 7)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR11_MOUSE
θ value	3.17815e-21 (rank : 10)	NC score	0.792028 (rank : 11)
Query Neighborhood Hits	123	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR21_HUMAN
θ value	7.82807e-20 (rank : 11)	NC score	0.786584 (rank : 13)
Query Neighborhood Hits	123	Target Neighborhood Hits	90	Shared Neighborhood Hits	50
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR5_HUMAN
θ value	1.47631e-18 (rank : 12)	NC score	0.816239 (rank : 8)
Query Neighborhood Hits	123	Target Neighborhood Hits	102	Shared Neighborhood Hits	58
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR14_HUMAN
θ value	4.02038e-16 (rank : 13)	NC score	0.806210 (rank : 9)
Query Neighborhood Hits	123	Target Neighborhood Hits	149	Shared Neighborhood Hits	68
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR5_MOUSE
θ value	2.43908e-13 (rank : 14)	NC score	0.793557 (rank : 10)
Query Neighborhood Hits	123	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR8_HUMAN
θ value	3.52202e-12 (rank : 15)	NC score	0.659455 (rank : 23)
Query Neighborhood Hits	123	Target Neighborhood Hits	198	Shared Neighborhood Hits	57
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR1A_HUMAN
θ value	1.33837e-11 (rank : 16)	NC score	0.645268 (rank : 26)
Query Neighborhood Hits	123	Target Neighborhood Hits	121	Shared Neighborhood Hits	52
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR16_MOUSE
θ value	2.28291e-11 (rank : 17)	NC score	0.664137 (rank : 22)
Query Neighborhood Hits	123	Target Neighborhood Hits	178	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR9_HUMAN
θ value	6.64225e-11 (rank : 18)	NC score	0.688698 (rank : 20)
Query Neighborhood Hits	123	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR16_HUMAN
θ value	2.52405e-10 (rank : 19)	NC score	0.652156 (rank : 25)
Query Neighborhood Hits	123	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR1A_MOUSE
θ value	2.52405e-10 (rank : 20)	NC score	0.656080 (rank : 24)
Query Neighborhood Hits	123	Target Neighborhood Hits	131	Shared Neighborhood Hits	52
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR4_HUMAN
θ value	2.52405e-10 (rank : 21)	NC score	0.715365 (rank : 16)
Query Neighborhood Hits	123	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR26_MOUSE
θ value	5.62301e-10 (rank : 22)	NC score	0.725471 (rank : 15)
Query Neighborhood Hits	123	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR4_MOUSE
θ value	9.59137e-10 (rank : 23)	NC score	0.695513 (rank : 18)
Query Neighborhood Hits	123	Target Neighborhood Hits	137	Shared Neighborhood Hits	61
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR22_MOUSE
θ value	6.21693e-09 (rank : 24)	NC score	0.705182 (rank : 17)
Query Neighborhood Hits	123	Target Neighborhood Hits	97	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR9_MOUSE
θ value	6.21693e-09 (rank : 25)	NC score	0.689048 (rank : 19)
Query Neighborhood Hits	123	Target Neighborhood Hits	137	Shared Neighborhood Hits	62
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR23_MOUSE
θ value	2.36244e-08 (rank : 26)	NC score	0.684785 (rank : 21)
Query Neighborhood Hits	123	Target Neighborhood Hits	114	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TR10B_HUMAN
θ value	4.92598e-06 (rank : 27)	NC score	0.502761 (rank : 32)
Query Neighborhood Hits	123	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TNR27_HUMAN
θ value	9.29e-05 (rank : 28)	NC score	0.381128 (rank : 40)
Query Neighborhood Hits	123	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR6_MOUSE
θ value	9.29e-05 (rank : 29)	NC score	0.601496 (rank : 27)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TR10A_HUMAN
θ value	9.29e-05 (rank : 30)	NC score	0.474195 (rank : 36)
Query Neighborhood Hits	123	Target Neighborhood Hits	82	Shared Neighborhood Hits	44
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TNR8_MOUSE
θ value	0.000158464 (rank : 31)	NC score	0.532622 (rank : 29)
Query Neighborhood Hits	123	Target Neighborhood Hits	208	Shared Neighborhood Hits	56
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR18_HUMAN
θ value	0.00020696 (rank : 32)	NC score	0.497074 (rank : 33)
Query Neighborhood Hits	123	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TR10D_HUMAN
θ value	0.00020696 (rank : 33)	NC score	0.463053 (rank : 37)
Query Neighborhood Hits	123	Target Neighborhood Hits	62	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TNR6_HUMAN
θ value	0.00035302 (rank : 34)	NC score	0.568095 (rank : 28)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	47
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR27_MOUSE
θ value	0.000786445 (rank : 35)	NC score	0.328158 (rank : 41)
Query Neighborhood Hits	123	Target Neighborhood Hits	61	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TR10B_MOUSE
θ value	0.00298849 (rank : 36)	NC score	0.435349 (rank : 38)
Query Neighborhood Hits	123	Target Neighborhood Hits	76	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR10C_HUMAN
θ value	0.00869519 (rank : 37)	NC score	0.495407 (rank : 34)
Query Neighborhood Hits	123	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

PCSK5_MOUSE
θ value	0.0113563 (rank : 38)	NC score	0.153583 (rank : 48)
Query Neighborhood Hits	123	Target Neighborhood Hits	613	Shared Neighborhood Hits	82
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TNR25_HUMAN
θ value	0.0113563 (rank : 39)	NC score	0.529690 (rank : 30)
Query Neighborhood Hits	123	Target Neighborhood Hits	172	Shared Neighborhood Hits	64
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR7_HUMAN
θ value	0.0193708 (rank : 40)	NC score	0.521168 (rank : 31)
Query Neighborhood Hits	123	Target Neighborhood Hits	120	Shared Neighborhood Hits	53
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

FURIN_HUMAN
θ value	0.0252991 (rank : 41)	NC score	0.081357 (rank : 59)
Query Neighborhood Hits	123	Target Neighborhood Hits	52	Shared Neighborhood Hits	14
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

TNR18_MOUSE
θ value	0.0252991 (rank : 42)	NC score	0.387810 (rank : 39)
Query Neighborhood Hits	123	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TR19L_HUMAN
θ value	0.0330416 (rank : 43)	NC score	0.307840 (rank : 42)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	0.0330416 (rank : 44)	NC score	0.301421 (rank : 43)
Query Neighborhood Hits	123	Target Neighborhood Hits	85	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

PCSK4_HUMAN
θ value	0.0563607 (rank : 45)	NC score	0.069109 (rank : 66)
Query Neighborhood Hits	123	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

FURIN_MOUSE
θ value	0.0736092 (rank : 46)	NC score	0.080394 (rank : 60)
Query Neighborhood Hits	123	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

ZPBP2_MOUSE
θ value	0.0736092 (rank : 47)	NC score	0.076421 (rank : 61)
Query Neighborhood Hits	123	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q6X786, Q6X785, Q9DA91	Gene names	Zpbp2
Domain Architecture	No domain graphic available
Description	Zona pellucida-binding protein 2 precursor.

EDAR_MOUSE
θ value	0.0961366 (rank : 48)	NC score	0.196655 (rank : 47)
Query Neighborhood Hits	123	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

EDAR_HUMAN
θ value	0.125558 (rank : 49)	NC score	0.199363 (rank : 46)
Query Neighborhood Hits	123	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

FRAS1_MOUSE
θ value	0.125558 (rank : 50)	NC score	0.089760 (rank : 54)
Query Neighborhood Hits	123	Target Neighborhood Hits	747	Shared Neighborhood Hits	70
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GEMI5_MOUSE
θ value	0.21417 (rank : 51)	NC score	0.021340 (rank : 126)
Query Neighborhood Hits	123	Target Neighborhood Hits	424	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

MAGB6_HUMAN
θ value	0.279714 (rank : 52)	NC score	0.015258 (rank : 131)
Query Neighborhood Hits	123	Target Neighborhood Hits	184	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N7X4, Q6GS19, Q9H219	Gene names	MAGEB6
Domain Architecture
Description	Melanoma-associated antigen B6 (MAGE-B6 antigen).

TNR6A_HUMAN
θ value	0.279714 (rank : 53)	NC score	0.041858 (rank : 110)
Query Neighborhood Hits	123	Target Neighborhood Hits	343	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

LAMC3_MOUSE
θ value	0.365318 (rank : 54)	NC score	0.095840 (rank : 52)
Query Neighborhood Hits	123	Target Neighborhood Hits	624	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

TNR7_MOUSE
θ value	0.365318 (rank : 55)	NC score	0.478539 (rank : 35)
Query Neighborhood Hits	123	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

KR107_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.057953 (rank : 86)
Query Neighborhood Hits	123	Target Neighborhood Hits	330	Shared Neighborhood Hits	34
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

MK07_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.000205 (rank : 154)
Query Neighborhood Hits	123	Target Neighborhood Hits	1087	Shared Neighborhood Hits	11
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

NRG3_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.032710 (rank : 121)
Query Neighborhood Hits	123	Target Neighborhood Hits	132	Shared Neighborhood Hits	13
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

USH2A_MOUSE
θ value	0.47712 (rank : 59)	NC score	0.063608 (rank : 75)
Query Neighborhood Hits	123	Target Neighborhood Hits	626	Shared Neighborhood Hits	61
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

STAB2_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.054356 (rank : 97)
Query Neighborhood Hits	123	Target Neighborhood Hits	534	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

ZPBP2_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.055940 (rank : 92)
Query Neighborhood Hits	123	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q6X784, Q6X783, Q86XL5	Gene names	ZPBP2, ZPBPL
Domain Architecture	No domain graphic available
Description	Zona pellucida-binding protein 2 precursor (ZPBP-like protein).

5NT1B_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.027374 (rank : 124)
Query Neighborhood Hits	123	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

NOTC2_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.035978 (rank : 118)
Query Neighborhood Hits	123	Target Neighborhood Hits	1113	Shared Neighborhood Hits	51
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SREC_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.073336 (rank : 63)
Query Neighborhood Hits	123	Target Neighborhood Hits	645	Shared Neighborhood Hits	63
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_MOUSE
θ value	0.813845 (rank : 65)	NC score	0.061543 (rank : 78)
Query Neighborhood Hits	123	Target Neighborhood Hits	566	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

LAMC2_MOUSE
θ value	1.06291 (rank : 66)	NC score	0.082499 (rank : 58)
Query Neighborhood Hits	123	Target Neighborhood Hits	614	Shared Neighborhood Hits	68
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LRP3_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.020693 (rank : 128)
Query Neighborhood Hits	123	Target Neighborhood Hits	280	Shared Neighborhood Hits	24
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

NOTC4_MOUSE
θ value	1.06291 (rank : 68)	NC score	0.040042 (rank : 114)
Query Neighborhood Hits	123	Target Neighborhood Hits	872	Shared Neighborhood Hits	48
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PCSK5_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.109989 (rank : 49)
Query Neighborhood Hits	123	Target Neighborhood Hits	291	Shared Neighborhood Hits	56
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

ZAN_MOUSE
θ value	1.06291 (rank : 70)	NC score	0.093636 (rank : 53)
Query Neighborhood Hits	123	Target Neighborhood Hits	808	Shared Neighborhood Hits	68
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

EPHB4_HUMAN
θ value	1.38821 (rank : 71)	NC score	0.006970 (rank : 144)
Query Neighborhood Hits	123	Target Neighborhood Hits	1056	Shared Neighborhood Hits	38
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

FA12_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.009938 (rank : 140)
Query Neighborhood Hits	123	Target Neighborhood Hits	425	Shared Neighborhood Hits	26
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

PARM1_MOUSE
θ value	1.38821 (rank : 73)	NC score	0.029547 (rank : 122)
Query Neighborhood Hits	123	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

FRAS1_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.097374 (rank : 51)
Query Neighborhood Hits	123	Target Neighborhood Hits	759	Shared Neighborhood Hits	69
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA3_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.059115 (rank : 81)
Query Neighborhood Hits	123	Target Neighborhood Hits	760	Shared Neighborhood Hits	54
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

NOTC3_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.038489 (rank : 117)
Query Neighborhood Hits	123	Target Neighborhood Hits	975	Shared Neighborhood Hits	48
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

STON1_MOUSE
θ value	1.81305 (rank : 77)	NC score	0.017927 (rank : 129)
Query Neighborhood Hits	123	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

TP53B_MOUSE
θ value	1.81305 (rank : 78)	NC score	0.017026 (rank : 130)
Query Neighborhood Hits	123	Target Neighborhood Hits	644	Shared Neighborhood Hits	12
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ALMS1_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.020731 (rank : 127)
Query Neighborhood Hits	123	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

NOTC3_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.040235 (rank : 113)
Query Neighborhood Hits	123	Target Neighborhood Hits	1062	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.040494 (rank : 112)
Query Neighborhood Hits	123	Target Neighborhood Hits	905	Shared Neighborhood Hits	48
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

RAB3I_MOUSE
θ value	2.36792 (rank : 82)	NC score	0.022520 (rank : 125)
Query Neighborhood Hits	123	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q68EF0	Gene names	Rab3ip
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

ZEP1_MOUSE
θ value	2.36792 (rank : 83)	NC score	0.001780 (rank : 153)
Query Neighborhood Hits	123	Target Neighborhood Hits	1063	Shared Neighborhood Hits	10
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

CREL1_MOUSE
θ value	3.0926 (rank : 84)	NC score	0.049618 (rank : 106)
Query Neighborhood Hits	123	Target Neighborhood Hits	524	Shared Neighborhood Hits	42
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LAMC2_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.068355 (rank : 67)
Query Neighborhood Hits	123	Target Neighborhood Hits	715	Shared Neighborhood Hits	61
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

MUCDL_MOUSE
θ value	3.0926 (rank : 86)	NC score	0.011359 (rank : 138)
Query Neighborhood Hits	123	Target Neighborhood Hits	461	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

SMOO_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.012423 (rank : 136)
Query Neighborhood Hits	123	Target Neighborhood Hits	391	Shared Neighborhood Hits	8
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TTC28_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.014016 (rank : 134)
Query Neighborhood Hits	123	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

BIRC6_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.013041 (rank : 135)
Query Neighborhood Hits	123	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

CREL1_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.051387 (rank : 102)
Query Neighborhood Hits	123	Target Neighborhood Hits	441	Shared Neighborhood Hits	44
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LTBP2_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.043306 (rank : 109)
Query Neighborhood Hits	123	Target Neighborhood Hits	617	Shared Neighborhood Hits	48
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MYST4_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.007898 (rank : 141)
Query Neighborhood Hits	123	Target Neighborhood Hits	671	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

ZPBP1_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.038840 (rank : 116)
Query Neighborhood Hits	123	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q62522, Q9CR97	Gene names	Zpbp, Zpbp1
Domain Architecture	No domain graphic available
Description	Zona pellucida-binding protein 1 precursor (Sp38).

AATK_HUMAN
θ value	5.27518 (rank : 94)	NC score	-0.001024 (rank : 155)
Query Neighborhood Hits	123	Target Neighborhood Hits	1243	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ADM1B_MOUSE
θ value	5.27518 (rank : 95)	NC score	0.005915 (rank : 147)
Query Neighborhood Hits	123	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

FILA_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.011498 (rank : 137)
Query Neighborhood Hits	123	Target Neighborhood Hits	685	Shared Neighborhood Hits	6
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

LAMA3_MOUSE
θ value	5.27518 (rank : 97)	NC score	0.065911 (rank : 70)
Query Neighborhood Hits	123	Target Neighborhood Hits	859	Shared Neighborhood Hits	67
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

MUC2_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.028713 (rank : 123)
Query Neighborhood Hits	123	Target Neighborhood Hits	906	Shared Neighborhood Hits	45
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MUC5B_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.041226 (rank : 111)
Query Neighborhood Hits	123	Target Neighborhood Hits	1020	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NOTC2_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.033009 (rank : 120)
Query Neighborhood Hits	123	Target Neighborhood Hits	1069	Shared Neighborhood Hits	49
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

REST_HUMAN
θ value	5.27518 (rank : 101)	NC score	-0.002031 (rank : 156)
Query Neighborhood Hits	123	Target Neighborhood Hits	1605	Shared Neighborhood Hits	10
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CB010_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.014497 (rank : 133)
Query Neighborhood Hits	123	Target Neighborhood Hits	130	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

CELR3_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.014873 (rank : 132)
Query Neighborhood Hits	123	Target Neighborhood Hits	687	Shared Neighborhood Hits	45
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

LTBP2_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.039452 (rank : 115)
Query Neighborhood Hits	123	Target Neighborhood Hits	552	Shared Neighborhood Hits	46
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SCUB3_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.067328 (rank : 69)
Query Neighborhood Hits	123	Target Neighborhood Hits	428	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SEPT3_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.006755 (rank : 145)
Query Neighborhood Hits	123	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UH03, Q6IBZ6, Q8N3P3	Gene names	SEPT3, SEP3
Domain Architecture
Description	Neuronal-specific septin-3.

SEPT3_MOUSE
θ value	6.88961 (rank : 107)	NC score	0.007079 (rank : 143)
Query Neighborhood Hits	123	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1S5	Gene names	Sept3, Sep3
Domain Architecture
Description	Neuronal-specific septin-3.

TS1R2_MOUSE
θ value	6.88961 (rank : 108)	NC score	0.007744 (rank : 142)
Query Neighborhood Hits	123	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

ZAN_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.045429 (rank : 108)
Query Neighborhood Hits	123	Target Neighborhood Hits	679	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CBWD1_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.011015 (rank : 139)
Query Neighborhood Hits	123	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRT8, Q49AJ1, Q5VVK2, Q6VBU6, Q7Z5Z0, Q7Z652, Q9BY38, Q9NYD0	Gene names	CBWD1
Domain Architecture	No domain graphic available
Description	COBW domain-containing protein 1 (COBP) (NPC-A-6 COBW domain- containing protein 1) (NPC-A-6).

CIC_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.002513 (rank : 151)
Query Neighborhood Hits	123	Target Neighborhood Hits	992	Shared Neighborhood Hits	11
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CSRP1_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.003361 (rank : 150)
Query Neighborhood Hits	123	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	P97315	Gene names	Csrp1, Crp1, Csrp
Domain Architecture
Description	Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP1) (CRP).

DMXL1_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.005492 (rank : 148)
Query Neighborhood Hits	123	Target Neighborhood Hits	259	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

GASP2_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.005929 (rank : 146)
Query Neighborhood Hits	123	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q96D09, Q8NAB4	Gene names	GPRASP2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

JADE2_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.005162 (rank : 149)
Query Neighborhood Hits	123	Target Neighborhood Hits	560	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

KR101_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.050260 (rank : 105)
Query Neighborhood Hits	123	Target Neighborhood Hits	261	Shared Neighborhood Hits	33
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR10B_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.034789 (rank : 119)
Query Neighborhood Hits	123	Target Neighborhood Hits	269	Shared Neighborhood Hits	26
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LAMB2_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.057987 (rank : 84)
Query Neighborhood Hits	123	Target Neighborhood Hits	692	Shared Neighborhood Hits	56
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

MPDZ_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.001985 (rank : 152)
Query Neighborhood Hits	123	Target Neighborhood Hits	298	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

PGBM_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.046990 (rank : 107)
Query Neighborhood Hits	123	Target Neighborhood Hits	1073	Shared Neighborhood Hits	67
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SCUB3_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.068190 (rank : 68)
Query Neighborhood Hits	123	Target Neighborhood Hits	442	Shared Neighborhood Hits	65
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TITIN_HUMAN
θ value	8.99809 (rank : 122)	NC score	-0.002965 (rank : 157)
Query Neighborhood Hits	123	Target Neighborhood Hits	2923	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZNF77_HUMAN
θ value	8.99809 (rank : 123)	NC score	-0.004162 (rank : 158)
Query Neighborhood Hits	123	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q15935, Q86XJ3, Q9NPP0	Gene names	ZNF77
Domain Architecture	No domain graphic available
Description	Zinc finger protein 77 (ZNFpT1).

KR104_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.052243 (rank : 101)
Query Neighborhood Hits	123	Target Neighborhood Hits	313	Shared Neighborhood Hits	33
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KRA51_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.054222 (rank : 98)
Query Neighborhood Hits	123	Target Neighborhood Hits	288	Shared Neighborhood Hits	36
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.054957 (rank : 94)
Query Neighborhood Hits	123	Target Neighborhood Hits	236	Shared Neighborhood Hits	33
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.057344 (rank : 88)
Query Neighborhood Hits	123	Target Neighborhood Hits	331	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.065102 (rank : 72)
Query Neighborhood Hits	123	Target Neighborhood Hits	270	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA56_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.056346 (rank : 91)
Query Neighborhood Hits	123	Target Neighborhood Hits	207	Shared Neighborhood Hits	34
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA58_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.054078 (rank : 99)
Query Neighborhood Hits	123	Target Neighborhood Hits	324	Shared Neighborhood Hits	38
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.069333 (rank : 65)
Query Neighborhood Hits	123	Target Neighborhood Hits	310	Shared Neighborhood Hits	40
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMA1_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.062680 (rank : 76)
Query Neighborhood Hits	123	Target Neighborhood Hits	804	Shared Neighborhood Hits	58
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.064394 (rank : 73)
Query Neighborhood Hits	123	Target Neighborhood Hits	838	Shared Neighborhood Hits	69
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.058340 (rank : 83)
Query Neighborhood Hits	123	Target Neighborhood Hits	1092	Shared Neighborhood Hits	67
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.050912 (rank : 104)
Query Neighborhood Hits	123	Target Neighborhood Hits	1198	Shared Neighborhood Hits	61
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA5_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.085870 (rank : 55)
Query Neighborhood Hits	123	Target Neighborhood Hits	976	Shared Neighborhood Hits	72
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.083362 (rank : 57)
Query Neighborhood Hits	123	Target Neighborhood Hits	828	Shared Neighborhood Hits	71
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.054487 (rank : 96)
Query Neighborhood Hits	123	Target Neighborhood Hits	1018	Shared Neighborhood Hits	57
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.056454 (rank : 90)
Query Neighborhood Hits	123	Target Neighborhood Hits	919	Shared Neighborhood Hits	61
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.061072 (rank : 79)
Query Neighborhood Hits	123	Target Neighborhood Hits	722	Shared Neighborhood Hits	60
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMC1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.072065 (rank : 64)
Query Neighborhood Hits	123	Target Neighborhood Hits	922	Shared Neighborhood Hits	64
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.063776 (rank : 74)
Query Neighborhood Hits	123	Target Neighborhood Hits	856	Shared Neighborhood Hits	61
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.083475 (rank : 56)
Query Neighborhood Hits	123	Target Neighborhood Hits	588	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MEGF6_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.057635 (rank : 87)
Query Neighborhood Hits	123	Target Neighborhood Hits	671	Shared Neighborhood Hits	62
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF8_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.058471 (rank : 82)
Query Neighborhood Hits	123	Target Neighborhood Hits	528	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.075061 (rank : 62)
Query Neighborhood Hits	123	Target Neighborhood Hits	557	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.065693 (rank : 71)
Query Neighborhood Hits	123	Target Neighborhood Hits	896	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MT3_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.051063 (rank : 103)
Query Neighborhood Hits	123	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

PCSK4_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.052328 (rank : 100)
Query Neighborhood Hits	123	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

PCSK6_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.106878 (rank : 50)
Query Neighborhood Hits	123	Target Neighborhood Hits	298	Shared Neighborhood Hits	56
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

RSPO1_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.057979 (rank : 85)
Query Neighborhood Hits	123	Target Neighborhood Hits	101	Shared Neighborhood Hits	23
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

SREC2_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.062648 (rank : 77)
Query Neighborhood Hits	123	Target Neighborhood Hits	645	Shared Neighborhood Hits	54
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.056492 (rank : 89)
Query Neighborhood Hits	123	Target Neighborhood Hits	605	Shared Neighborhood Hits	57
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

STAB1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.060526 (rank : 80)
Query Neighborhood Hits	123	Target Neighborhood Hits	546	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB2_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.054901 (rank : 95)
Query Neighborhood Hits	123	Target Neighborhood Hits	528	Shared Neighborhood Hits	57
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TNR19_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.219400 (rank : 45)
Query Neighborhood Hits	123	Target Neighborhood Hits	89	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.273368 (rank : 44)
Query Neighborhood Hits	123	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

USH2A_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.055039 (rank : 93)
Query Neighborhood Hits	123	Target Neighborhood Hits	600	Shared Neighborhood Hits	58
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

Hits sorted by NC score

TNR1B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	123	Target Neighborhood Hits	123	Shared Neighborhood Hits	123
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR1B_HUMAN
NC score	0.967517 (rank : 2)	θ value	3.87392e-144 (rank : 2)
Query Neighborhood Hits	123	Target Neighborhood Hits	127	Shared Neighborhood Hits	64
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR6B_HUMAN
NC score	0.873760 (rank : 3)	θ value	6.61148e-27 (rank : 4)
Query Neighborhood Hits	123	Target Neighborhood Hits	103	Shared Neighborhood Hits	58
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TR11B_HUMAN
NC score	0.859525 (rank : 4)	θ value	2.42779e-29 (rank : 3)
Query Neighborhood Hits	123	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR11B_MOUSE
NC score	0.848563 (rank : 5)	θ value	2.51237e-26 (rank : 5)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	54
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR3_HUMAN
NC score	0.839048 (rank : 6)	θ value	3.62785e-25 (rank : 6)
Query Neighborhood Hits	123	Target Neighborhood Hits	145	Shared Neighborhood Hits	60
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR3_MOUSE
NC score	0.826780 (rank : 7)	θ value	1.6852e-22 (rank : 9)
Query Neighborhood Hits	123	Target Neighborhood Hits	113	Shared Neighborhood Hits	61
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR5_HUMAN
NC score	0.816239 (rank : 8)	θ value	1.47631e-18 (rank : 12)
Query Neighborhood Hits	123	Target Neighborhood Hits	102	Shared Neighborhood Hits	58
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR14_HUMAN
NC score	0.806210 (rank : 9)	θ value	4.02038e-16 (rank : 13)
Query Neighborhood Hits	123	Target Neighborhood Hits	149	Shared Neighborhood Hits	68
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR5_MOUSE
NC score	0.793557 (rank : 10)	θ value	2.43908e-13 (rank : 14)
Query Neighborhood Hits	123	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR11_MOUSE
NC score	0.792028 (rank : 11)	θ value	3.17815e-21 (rank : 10)
Query Neighborhood Hits	123	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR11_HUMAN
NC score	0.789072 (rank : 12)	θ value	9.87957e-23 (rank : 8)
Query Neighborhood Hits	123	Target Neighborhood Hits	135	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR21_HUMAN
NC score	0.786584 (rank : 13)	θ value	7.82807e-20 (rank : 11)
Query Neighborhood Hits	123	Target Neighborhood Hits	90	Shared Neighborhood Hits	50
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
NC score	0.782962 (rank : 14)	θ value	3.39556e-23 (rank : 7)
Query Neighborhood Hits	123	Target Neighborhood Hits	108	Shared Neighborhood Hits	51
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR26_MOUSE
NC score	0.725471 (rank : 15)	θ value	5.62301e-10 (rank : 22)
Query Neighborhood Hits	123	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR4_HUMAN
NC score	0.715365 (rank : 16)	θ value	2.52405e-10 (rank : 21)
Query Neighborhood Hits	123	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR22_MOUSE
NC score	0.705182 (rank : 17)	θ value	6.21693e-09 (rank : 24)
Query Neighborhood Hits	123	Target Neighborhood Hits	97	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR4_MOUSE
NC score	0.695513 (rank : 18)	θ value	9.59137e-10 (rank : 23)
Query Neighborhood Hits	123	Target Neighborhood Hits	137	Shared Neighborhood Hits	61
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR9_MOUSE
NC score	0.689048 (rank : 19)	θ value	6.21693e-09 (rank : 25)
Query Neighborhood Hits	123	Target Neighborhood Hits	137	Shared Neighborhood Hits	62
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR9_HUMAN
NC score	0.688698 (rank : 20)	θ value	6.64225e-11 (rank : 18)
Query Neighborhood Hits	123	Target Neighborhood Hits	166	Shared Neighborhood Hits	64
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR23_MOUSE
NC score	0.684785 (rank : 21)	θ value	2.36244e-08 (rank : 26)
Query Neighborhood Hits	123	Target Neighborhood Hits	114	Shared Neighborhood Hits	58
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR16_MOUSE
NC score	0.664137 (rank : 22)	θ value	2.28291e-11 (rank : 17)
Query Neighborhood Hits	123	Target Neighborhood Hits	178	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR8_HUMAN
NC score	0.659455 (rank : 23)	θ value	3.52202e-12 (rank : 15)
Query Neighborhood Hits	123	Target Neighborhood Hits	198	Shared Neighborhood Hits	57
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR1A_MOUSE
NC score	0.656080 (rank : 24)	θ value	2.52405e-10 (rank : 20)
Query Neighborhood Hits	123	Target Neighborhood Hits	131	Shared Neighborhood Hits	52
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR16_HUMAN
NC score	0.652156 (rank : 25)	θ value	2.52405e-10 (rank : 19)
Query Neighborhood Hits	123	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR1A_HUMAN
NC score	0.645268 (rank : 26)	θ value	1.33837e-11 (rank : 16)
Query Neighborhood Hits	123	Target Neighborhood Hits	121	Shared Neighborhood Hits	52
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR6_MOUSE
NC score	0.601496 (rank : 27)	θ value	9.29e-05 (rank : 29)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_HUMAN
NC score	0.568095 (rank : 28)	θ value	0.00035302 (rank : 34)
Query Neighborhood Hits	123	Target Neighborhood Hits	95	Shared Neighborhood Hits	47
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR8_MOUSE
NC score	0.532622 (rank : 29)	θ value	0.000158464 (rank : 31)
Query Neighborhood Hits	123	Target Neighborhood Hits	208	Shared Neighborhood Hits	56
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR25_HUMAN
NC score	0.529690 (rank : 30)	θ value	0.0113563 (rank : 39)
Query Neighborhood Hits	123	Target Neighborhood Hits	172	Shared Neighborhood Hits	64
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR7_HUMAN
NC score	0.521168 (rank : 31)	θ value	0.0193708 (rank : 40)
Query Neighborhood Hits	123	Target Neighborhood Hits	120	Shared Neighborhood Hits	53
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TR10B_HUMAN
NC score	0.502761 (rank : 32)	θ value	4.92598e-06 (rank : 27)
Query Neighborhood Hits	123	Target Neighborhood Hits	71	Shared Neighborhood Hits	44
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TNR18_HUMAN
NC score	0.497074 (rank : 33)	θ value	0.00020696 (rank : 32)
Query Neighborhood Hits	123	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TR10C_HUMAN
NC score	0.495407 (rank : 34)	θ value	0.00869519 (rank : 37)
Query Neighborhood Hits	123	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR7_MOUSE
NC score	0.478539 (rank : 35)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	123	Target Neighborhood Hits	112	Shared Neighborhood Hits	47
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TR10A_HUMAN
NC score	0.474195 (rank : 36)	θ value	9.29e-05 (rank : 30)
Query Neighborhood Hits	123	Target Neighborhood Hits	82	Shared Neighborhood Hits	44
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10D_HUMAN
NC score	0.463053 (rank : 37)	θ value	0.00020696 (rank : 33)
Query Neighborhood Hits	123	Target Neighborhood Hits	62	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10B_MOUSE
NC score	0.435349 (rank : 38)	θ value	0.00298849 (rank : 36)
Query Neighborhood Hits	123	Target Neighborhood Hits	76	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR18_MOUSE
NC score	0.387810 (rank : 39)	θ value	0.0252991 (rank : 42)
Query Neighborhood Hits	123	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR27_HUMAN
NC score	0.381128 (rank : 40)	θ value	9.29e-05 (rank : 28)
Query Neighborhood Hits	123	Target Neighborhood Hits	69	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR27_MOUSE
NC score	0.328158 (rank : 41)	θ value	0.000786445 (rank : 35)
Query Neighborhood Hits	123	Target Neighborhood Hits	61	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TR19L_HUMAN
NC score	0.307840 (rank : 42)	θ value	0.0330416 (rank : 43)
Query Neighborhood Hits	123	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
NC score	0.301421 (rank : 43)	θ value	0.0330416 (rank : 44)
Query Neighborhood Hits	123	Target Neighborhood Hits	85	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TNR19_MOUSE
NC score	0.273368 (rank : 44)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	123	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_HUMAN
NC score	0.219400 (rank : 45)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	123	Target Neighborhood Hits	89	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

EDAR_HUMAN
NC score	0.199363 (rank : 46)	θ value	0.125558 (rank : 49)
Query Neighborhood Hits	123	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

EDAR_MOUSE
NC score	0.196655 (rank : 47)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	123	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

PCSK5_MOUSE
NC score	0.153583 (rank : 48)	θ value	0.0113563 (rank : 38)
Query Neighborhood Hits	123	Target Neighborhood Hits	613	Shared Neighborhood Hits	82
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK5_HUMAN
NC score	0.109989 (rank : 49)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	123	Target Neighborhood Hits	291	Shared Neighborhood Hits	56
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK6_HUMAN
NC score	0.106878 (rank : 50)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	123	Target Neighborhood Hits	298	Shared Neighborhood Hits	56
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

FRAS1_HUMAN
NC score	0.097374 (rank : 51)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	123	Target Neighborhood Hits	759	Shared Neighborhood Hits	69
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMC3_MOUSE
NC score	0.095840 (rank : 52)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	123	Target Neighborhood Hits	624	Shared Neighborhood Hits	66
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

ZAN_MOUSE
NC score	0.093636 (rank : 53)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	123	Target Neighborhood Hits	808	Shared Neighborhood Hits	68
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

FRAS1_MOUSE
NC score	0.089760 (rank : 54)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	123	Target Neighborhood Hits	747	Shared Neighborhood Hits	70
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA5_HUMAN
NC score	0.085870 (rank : 55)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	123	Target Neighborhood Hits	976	Shared Neighborhood Hits	72
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC3_HUMAN
NC score	0.083475 (rank : 56)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	123	Target Neighborhood Hits	588	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_MOUSE
NC score	0.083362 (rank : 57)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	123	Target Neighborhood Hits	828	Shared Neighborhood Hits	71
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC2_MOUSE
NC score	0.082499 (rank : 58)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	123	Target Neighborhood Hits	614	Shared Neighborhood Hits	68
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

FURIN_HUMAN
NC score	0.081357 (rank : 59)	θ value	0.0252991 (rank : 41)
Query Neighborhood Hits	123	Target Neighborhood Hits	52	Shared Neighborhood Hits	14
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

FURIN_MOUSE
NC score	0.080394 (rank : 60)	θ value	0.0736092 (rank : 46)
Query Neighborhood Hits	123	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

ZPBP2_MOUSE
NC score	0.076421 (rank : 61)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	123	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q6X786, Q6X785, Q9DA91	Gene names	Zpbp2
Domain Architecture	No domain graphic available
Description	Zona pellucida-binding protein 2 precursor.

MEGF9_HUMAN
NC score	0.075061 (rank : 62)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	123	Target Neighborhood Hits	557	Shared Neighborhood Hits	59
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SREC_HUMAN
NC score	0.073336 (rank : 63)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	123	Target Neighborhood Hits	645	Shared Neighborhood Hits	63
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LAMC1_HUMAN
NC score	0.072065 (rank : 64)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	123	Target Neighborhood Hits	922	Shared Neighborhood Hits	64
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

KRA59_HUMAN
NC score	0.069333 (rank : 65)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	123	Target Neighborhood Hits	310	Shared Neighborhood Hits	40
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

PCSK4_HUMAN
NC score	0.069109 (rank : 66)	θ value	0.0563607 (rank : 45)
Query Neighborhood Hits	123	Target Neighborhood Hits	32	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

LAMC2_HUMAN
NC score	0.068355 (rank : 67)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	123	Target Neighborhood Hits	715	Shared Neighborhood Hits	61
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

SCUB3_MOUSE
NC score	0.068190 (rank : 68)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	123	Target Neighborhood Hits	442	Shared Neighborhood Hits	65
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_HUMAN
NC score	0.067328 (rank : 69)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	123	Target Neighborhood Hits	428	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMA3_MOUSE
NC score	0.065911 (rank : 70)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	123	Target Neighborhood Hits	859	Shared Neighborhood Hits	67
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

MEGF9_MOUSE
NC score	0.065693 (rank : 71)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	123	Target Neighborhood Hits	896	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KRA54_HUMAN
NC score	0.065102 (rank : 72)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	123	Target Neighborhood Hits	270	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LAMA1_MOUSE
NC score	0.064394 (rank : 73)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	123	Target Neighborhood Hits	838	Shared Neighborhood Hits	69
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC1_MOUSE
NC score	0.063776 (rank : 74)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	123	Target Neighborhood Hits	856	Shared Neighborhood Hits	61
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

USH2A_MOUSE
NC score	0.063608 (rank : 75)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	123	Target Neighborhood Hits	626	Shared Neighborhood Hits	61
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LAMA1_HUMAN
NC score	0.062680 (rank : 76)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	123	Target Neighborhood Hits	804	Shared Neighborhood Hits	58
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

SREC2_HUMAN
NC score	0.062648 (rank : 77)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	123	Target Neighborhood Hits	645	Shared Neighborhood Hits	54
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

STAB1_MOUSE
NC score	0.061543 (rank : 78)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	123	Target Neighborhood Hits	566	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

LAMB2_MOUSE
NC score	0.061072 (rank : 79)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	123	Target Neighborhood Hits	722	Shared Neighborhood Hits	60
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

STAB1_HUMAN
NC score	0.060526 (rank : 80)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	123	Target Neighborhood Hits	546	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

LAMA3_HUMAN
NC score	0.059115 (rank : 81)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	123	Target Neighborhood Hits	760	Shared Neighborhood Hits	54
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MEGF8_HUMAN
NC score	0.058471 (rank : 82)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	123	Target Neighborhood Hits	528	Shared Neighborhood Hits	57
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMA2_HUMAN
NC score	0.058340 (rank : 83)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	123	Target Neighborhood Hits	1092	Shared Neighborhood Hits	67
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB2_HUMAN
NC score	0.057987 (rank : 84)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	123	Target Neighborhood Hits	692	Shared Neighborhood Hits	56
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

RSPO1_HUMAN
NC score	0.057979 (rank : 85)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	123	Target Neighborhood Hits	101	Shared Neighborhood Hits	23
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

KR107_HUMAN
NC score	0.057953 (rank : 86)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	123	Target Neighborhood Hits	330	Shared Neighborhood Hits	34
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

MEGF6_HUMAN
NC score	0.057635 (rank : 87)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	123	Target Neighborhood Hits	671	Shared Neighborhood Hits	62
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KRA53_HUMAN
NC score	0.057344 (rank : 88)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	123	Target Neighborhood Hits	331	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

SREC2_MOUSE
NC score	0.056492 (rank : 89)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	123	Target Neighborhood Hits	605	Shared Neighborhood Hits	57
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

LAMB1_MOUSE
NC score	0.056454 (rank : 90)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	123	Target Neighborhood Hits	919	Shared Neighborhood Hits	61
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KRA56_HUMAN
NC score	0.056346 (rank : 91)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	123	Target Neighborhood Hits	207	Shared Neighborhood Hits	34
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

ZPBP2_HUMAN
NC score	0.055940 (rank : 92)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	123	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q6X784, Q6X783, Q86XL5	Gene names	ZPBP2, ZPBPL
Domain Architecture	No domain graphic available
Description	Zona pellucida-binding protein 2 precursor (ZPBP-like protein).

USH2A_HUMAN
NC score	0.055039 (rank : 93)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	123	Target Neighborhood Hits	600	Shared Neighborhood Hits	58
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

KRA52_HUMAN
NC score	0.054957 (rank : 94)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	123	Target Neighborhood Hits	236	Shared Neighborhood Hits	33
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

STAB2_MOUSE
NC score	0.054901 (rank : 95)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	123	Target Neighborhood Hits	528	Shared Neighborhood Hits	57
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

LAMB1_HUMAN
NC score	0.054487 (rank : 96)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	123	Target Neighborhood Hits	1018	Shared Neighborhood Hits	57
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

STAB2_HUMAN
NC score	0.054356 (rank : 97)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	123	Target Neighborhood Hits	534	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

KRA51_HUMAN
NC score	0.054222 (rank : 98)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	123	Target Neighborhood Hits	288	Shared Neighborhood Hits	36
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA58_HUMAN
NC score	0.054078 (rank : 99)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	123	Target Neighborhood Hits	324	Shared Neighborhood Hits	38
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

PCSK4_MOUSE
NC score	0.052328 (rank : 100)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	123	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	P29121, Q62094	Gene names	Pcsk4, Nec-3, Nec3
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3).

KR104_HUMAN
NC score	0.052243 (rank : 101)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	123	Target Neighborhood Hits	313	Shared Neighborhood Hits	33
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

CREL1_HUMAN
NC score	0.051387 (rank : 102)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	123	Target Neighborhood Hits	441	Shared Neighborhood Hits	44
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

MT3_MOUSE
NC score	0.051063 (rank : 103)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	123	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

LAMA2_MOUSE
NC score	0.050912 (rank : 104)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	123	Target Neighborhood Hits	1198	Shared Neighborhood Hits	61
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

KR101_HUMAN
NC score	0.050260 (rank : 105)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	123	Target Neighborhood Hits	261	Shared Neighborhood Hits	33
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

CREL1_MOUSE
NC score	0.049618 (rank : 106)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	123	Target Neighborhood Hits	524	Shared Neighborhood Hits	42
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

PGBM_MOUSE
NC score	0.046990 (rank : 107)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	123	Target Neighborhood Hits	1073	Shared Neighborhood Hits	67
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ZAN_HUMAN
NC score	0.045429 (rank : 108)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	123	Target Neighborhood Hits	679	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

LTBP2_MOUSE
NC score	0.043306 (rank : 109)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	123	Target Neighborhood Hits	617	Shared Neighborhood Hits	48
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TNR6A_HUMAN
NC score	0.041858 (rank : 110)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	123	Target Neighborhood Hits	343	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

MUC5B_HUMAN
NC score	0.041226 (rank : 111)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	123	Target Neighborhood Hits	1020	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NOTC4_HUMAN
NC score	0.040494 (rank : 112)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	123	Target Neighborhood Hits	905	Shared Neighborhood Hits	48
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC3_HUMAN
NC score	0.040235 (rank : 113)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	123	Target Neighborhood Hits	1062	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
NC score	0.040042 (rank : 114)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	123	Target Neighborhood Hits	872	Shared Neighborhood Hits	48
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

LTBP2_HUMAN
NC score	0.039452 (rank : 115)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	123	Target Neighborhood Hits	552	Shared Neighborhood Hits	46
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

ZPBP1_MOUSE
NC score	0.038840 (rank : 116)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	123	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q62522, Q9CR97	Gene names	Zpbp, Zpbp1
Domain Architecture	No domain graphic available
Description	Zona pellucida-binding protein 1 precursor (Sp38).

NOTC3_MOUSE
NC score	0.038489 (rank : 117)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	123	Target Neighborhood Hits	975	Shared Neighborhood Hits	48
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
NC score	0.035978 (rank : 118)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	123	Target Neighborhood Hits	1113	Shared Neighborhood Hits	51
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KR10B_HUMAN
NC score	0.034789 (rank : 119)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	123	Target Neighborhood Hits	269	Shared Neighborhood Hits	26
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

NOTC2_MOUSE
NC score	0.033009 (rank : 120)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	123	Target Neighborhood Hits	1069	Shared Neighborhood Hits	49
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NRG3_MOUSE
NC score	0.032710 (rank : 121)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	123	Target Neighborhood Hits	132	Shared Neighborhood Hits	13
SwissProt Accessions	O35181	Gene names	Nrg3
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)].

PARM1_MOUSE
NC score	0.029547 (rank : 122)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	123	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	Q923D3, Q3TTV0, Q3UFU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein PARM-1 precursor.

MUC2_HUMAN
NC score	0.028713 (rank : 123)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	123	Target Neighborhood Hits	906	Shared Neighborhood Hits	45
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

5NT1B_HUMAN
NC score	0.027374 (rank : 124)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	123	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

RAB3I_MOUSE
NC score	0.022520 (rank : 125)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	123	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q68EF0	Gene names	Rab3ip
Domain Architecture	No domain graphic available
Description	RAB3A-interacting protein (Rabin-3) (SSX2-interacting protein).

GEMI5_MOUSE
NC score	0.021340 (rank : 126)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	123	Target Neighborhood Hits	424	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BX17	Gene names	Gemin5
Domain Architecture
Description	Gem-associated protein 5 (Gemin5).

ALMS1_HUMAN
NC score	0.020731 (rank : 127)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	123	Target Neighborhood Hits	356	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

LRP3_HUMAN
NC score	0.020693 (rank : 128)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	123	Target Neighborhood Hits	280	Shared Neighborhood Hits	24
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

STON1_MOUSE
NC score	0.017927 (rank : 129)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	123	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

TP53B_MOUSE
NC score	0.017026 (rank : 130)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	123	Target Neighborhood Hits	644	Shared Neighborhood Hits	12
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MAGB6_HUMAN
NC score	0.015258 (rank : 131)	θ value	0.279714 (rank : 52)
Query Neighborhood Hits	123	Target Neighborhood Hits	184	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N7X4, Q6GS19, Q9H219	Gene names	MAGEB6
Domain Architecture
Description	Melanoma-associated antigen B6 (MAGE-B6 antigen).

CELR3_MOUSE
NC score	0.014873 (rank : 132)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	123	Target Neighborhood Hits	687	Shared Neighborhood Hits	45
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CB010_HUMAN
NC score	0.014497 (rank : 133)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	123	Target Neighborhood Hits	130	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

TTC28_MOUSE
NC score	0.014016 (rank : 134)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	123	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

BIRC6_HUMAN
NC score	0.013041 (rank : 135)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	123	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

SMOO_HUMAN
NC score	0.012423 (rank : 136)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	123	Target Neighborhood Hits	391	Shared Neighborhood Hits	8
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

FILA_HUMAN
NC score	0.011498 (rank : 137)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	123	Target Neighborhood Hits	685	Shared Neighborhood Hits	6
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

MUCDL_MOUSE
NC score	0.011359 (rank : 138)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	123	Target Neighborhood Hits	461	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

CBWD1_HUMAN
NC score	0.011015 (rank : 139)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	123	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRT8, Q49AJ1, Q5VVK2, Q6VBU6, Q7Z5Z0, Q7Z652, Q9BY38, Q9NYD0	Gene names	CBWD1
Domain Architecture	No domain graphic available
Description	COBW domain-containing protein 1 (COBP) (NPC-A-6 COBW domain- containing protein 1) (NPC-A-6).

FA12_HUMAN
NC score	0.009938 (rank : 140)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	123	Target Neighborhood Hits	425	Shared Neighborhood Hits	26
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

MYST4_HUMAN
NC score	0.007898 (rank : 141)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	123	Target Neighborhood Hits	671	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

TS1R2_MOUSE
NC score	0.007744 (rank : 142)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	123	Target Neighborhood Hits	69	Shared Neighborhood Hits	9
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

SEPT3_MOUSE
NC score	0.007079 (rank : 143)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	123	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z1S5	Gene names	Sept3, Sep3
Domain Architecture
Description	Neuronal-specific septin-3.

EPHB4_HUMAN
NC score	0.006970 (rank : 144)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	123	Target Neighborhood Hits	1056	Shared Neighborhood Hits	38
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

SEPT3_HUMAN
NC score	0.006755 (rank : 145)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	123	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UH03, Q6IBZ6, Q8N3P3	Gene names	SEPT3, SEP3
Domain Architecture
Description	Neuronal-specific septin-3.

GASP2_HUMAN
NC score	0.005929 (rank : 146)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	123	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q96D09, Q8NAB4	Gene names	GPRASP2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

ADM1B_MOUSE
NC score	0.005915 (rank : 147)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	123	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

DMXL1_HUMAN
NC score	0.005492 (rank : 148)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	123	Target Neighborhood Hits	259	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

JADE2_MOUSE
NC score	0.005162 (rank : 149)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	123	Target Neighborhood Hits	560	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

CSRP1_MOUSE
NC score	0.003361 (rank : 150)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	123	Target Neighborhood Hits	132	Shared Neighborhood Hits	3
SwissProt Accessions	P97315	Gene names	Csrp1, Crp1, Csrp
Domain Architecture
Description	Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP1) (CRP).

CIC_HUMAN
NC score	0.002513 (rank : 151)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	123	Target Neighborhood Hits	992	Shared Neighborhood Hits	11
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MPDZ_MOUSE
NC score	0.001985 (rank : 152)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	123	Target Neighborhood Hits	298	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VBX6, O08783, Q6P7U4, Q80ZY8, Q8BKJ1, Q8C0H8, Q8VBV5, Q8VBY0, Q9Z1K3	Gene names	Mpdz, Mupp1
Domain Architecture	No domain graphic available
Description	Multiple PDZ domain protein (Multi PDZ domain protein 1) (Multi-PDZ domain protein 1).

ZEP1_MOUSE
NC score	0.001780 (rank : 153)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	123	Target Neighborhood Hits	1063	Shared Neighborhood Hits	10
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

MK07_HUMAN
NC score	0.000205 (rank : 154)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	123	Target Neighborhood Hits	1087	Shared Neighborhood Hits	11
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

AATK_HUMAN
NC score	-0.001024 (rank : 155)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	123	Target Neighborhood Hits	1243	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

REST_HUMAN
NC score	-0.002031 (rank : 156)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	123	Target Neighborhood Hits	1605	Shared Neighborhood Hits	10
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

TITIN_HUMAN
NC score	-0.002965 (rank : 157)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	123	Target Neighborhood Hits	2923	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZNF77_HUMAN
NC score	-0.004162 (rank : 158)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	123	Target Neighborhood Hits	759	Shared Neighborhood Hits	9
SwissProt Accessions	Q15935, Q86XJ3, Q9NPP0	Gene names	ZNF77
Domain Architecture	No domain graphic available
Description	Zinc finger protein 77 (ZNFpT1).