Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : TNR1B_HUMAN

For an explanation of this page, click here

TNR1B_HUMAN
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TNR1B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	127	Target Neighborhood Hits	127	Shared Neighborhood Hits	127
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1B_MOUSE
θ value	3.87392e-144 (rank : 2)	NC score	0.967517 (rank : 2)
Query Neighborhood Hits	127	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR6B_HUMAN
θ value	1.08979e-29 (rank : 3)	NC score	0.880240 (rank : 3)
Query Neighborhood Hits	127	Target Neighborhood Hits	103	Shared Neighborhood Hits	57
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TR11B_HUMAN
θ value	1.85889e-29 (rank : 4)	NC score	0.863546 (rank : 4)
Query Neighborhood Hits	127	Target Neighborhood Hits	92	Shared Neighborhood Hits	59
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR11B_MOUSE
θ value	2.51237e-26 (rank : 5)	NC score	0.853200 (rank : 6)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR3_HUMAN
θ value	3.28125e-26 (rank : 6)	NC score	0.855134 (rank : 5)
Query Neighborhood Hits	127	Target Neighborhood Hits	145	Shared Neighborhood Hits	71
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR21_HUMAN
θ value	1.24688e-25 (rank : 7)	NC score	0.792048 (rank : 13)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	49
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR5_HUMAN
θ value	2.12685e-25 (rank : 8)	NC score	0.843920 (rank : 7)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR21_MOUSE
θ value	8.08199e-25 (rank : 9)	NC score	0.784331 (rank : 14)
Query Neighborhood Hits	127	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR3_MOUSE
θ value	7.56453e-23 (rank : 10)	NC score	0.834768 (rank : 9)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	64
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR11_HUMAN
θ value	9.87957e-23 (rank : 11)	NC score	0.796432 (rank : 12)
Query Neighborhood Hits	127	Target Neighborhood Hits	135	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	9.24701e-21 (rank : 12)	NC score	0.798148 (rank : 11)
Query Neighborhood Hits	127	Target Neighborhood Hits	121	Shared Neighborhood Hits	63
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR14_HUMAN
θ value	1.5773e-20 (rank : 13)	NC score	0.836157 (rank : 8)
Query Neighborhood Hits	127	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR5_MOUSE
θ value	1.74391e-19 (rank : 14)	NC score	0.822278 (rank : 10)
Query Neighborhood Hits	127	Target Neighborhood Hits	131	Shared Neighborhood Hits	66
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR8_HUMAN
θ value	1.99529e-15 (rank : 15)	NC score	0.683610 (rank : 23)
Query Neighborhood Hits	127	Target Neighborhood Hits	198	Shared Neighborhood Hits	67
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR4_HUMAN
θ value	1.58096e-12 (rank : 16)	NC score	0.741717 (rank : 16)
Query Neighborhood Hits	127	Target Neighborhood Hits	152	Shared Neighborhood Hits	70
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR4_MOUSE
θ value	3.52202e-12 (rank : 17)	NC score	0.734042 (rank : 17)
Query Neighborhood Hits	127	Target Neighborhood Hits	137	Shared Neighborhood Hits	73
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR16_HUMAN
θ value	7.84624e-12 (rank : 18)	NC score	0.678477 (rank : 24)
Query Neighborhood Hits	127	Target Neighborhood Hits	183	Shared Neighborhood Hits	70
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR22_MOUSE
θ value	3.89403e-11 (rank : 19)	NC score	0.730961 (rank : 18)
Query Neighborhood Hits	127	Target Neighborhood Hits	97	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR16_MOUSE
θ value	1.47974e-10 (rank : 20)	NC score	0.684591 (rank : 22)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR1A_MOUSE
θ value	1.9326e-10 (rank : 21)	NC score	0.667973 (rank : 25)
Query Neighborhood Hits	127	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR9_MOUSE
θ value	3.29651e-10 (rank : 22)	NC score	0.700873 (rank : 20)
Query Neighborhood Hits	127	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR9_HUMAN
θ value	1.25267e-09 (rank : 23)	NC score	0.688560 (rank : 21)
Query Neighborhood Hits	127	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR26_MOUSE
θ value	1.63604e-09 (rank : 24)	NC score	0.748947 (rank : 15)
Query Neighborhood Hits	127	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR1A_HUMAN
θ value	1.80886e-08 (rank : 25)	NC score	0.646508 (rank : 26)
Query Neighborhood Hits	127	Target Neighborhood Hits	121	Shared Neighborhood Hits	55
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR23_MOUSE
θ value	6.87365e-08 (rank : 26)	NC score	0.715485 (rank : 19)
Query Neighborhood Hits	127	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR6_MOUSE
θ value	6.87365e-08 (rank : 27)	NC score	0.646265 (rank : 27)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	55
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TR10A_HUMAN
θ value	1.53129e-07 (rank : 28)	NC score	0.500846 (rank : 35)
Query Neighborhood Hits	127	Target Neighborhood Hits	82	Shared Neighborhood Hits	47
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TNR6_HUMAN
θ value	1.99992e-07 (rank : 29)	NC score	0.613362 (rank : 28)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	52
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR8_MOUSE
θ value	2.61198e-07 (rank : 30)	NC score	0.553549 (rank : 31)
Query Neighborhood Hits	127	Target Neighborhood Hits	208	Shared Neighborhood Hits	52
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TR10B_HUMAN
θ value	4.45536e-07 (rank : 31)	NC score	0.530298 (rank : 32)
Query Neighborhood Hits	127	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TNR7_HUMAN
θ value	8.40245e-06 (rank : 32)	NC score	0.573067 (rank : 29)
Query Neighborhood Hits	127	Target Neighborhood Hits	120	Shared Neighborhood Hits	59
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR25_HUMAN
θ value	1.43324e-05 (rank : 33)	NC score	0.562001 (rank : 30)
Query Neighborhood Hits	127	Target Neighborhood Hits	172	Shared Neighborhood Hits	64
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TR10C_HUMAN
θ value	1.87187e-05 (rank : 34)	NC score	0.524541 (rank : 34)
Query Neighborhood Hits	127	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR10D_HUMAN
θ value	1.87187e-05 (rank : 35)	NC score	0.487613 (rank : 37)
Query Neighborhood Hits	127	Target Neighborhood Hits	62	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TNR27_HUMAN
θ value	3.19293e-05 (rank : 36)	NC score	0.391896 (rank : 39)
Query Neighborhood Hits	127	Target Neighborhood Hits	69	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR18_HUMAN
θ value	0.000270298 (rank : 37)	NC score	0.489123 (rank : 36)
Query Neighborhood Hits	127	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR27_MOUSE
θ value	0.000786445 (rank : 38)	NC score	0.340032 (rank : 41)
Query Neighborhood Hits	127	Target Neighborhood Hits	61	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR7_MOUSE
θ value	0.00175202 (rank : 39)	NC score	0.527101 (rank : 33)
Query Neighborhood Hits	127	Target Neighborhood Hits	112	Shared Neighborhood Hits	50
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TR10B_MOUSE
θ value	0.00390308 (rank : 40)	NC score	0.464201 (rank : 38)
Query Neighborhood Hits	127	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

LAMC3_MOUSE
θ value	0.0113563 (rank : 41)	NC score	0.140298 (rank : 49)
Query Neighborhood Hits	127	Target Neighborhood Hits	624	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

SREC2_HUMAN
θ value	0.0113563 (rank : 42)	NC score	0.103666 (rank : 62)
Query Neighborhood Hits	127	Target Neighborhood Hits	645	Shared Neighborhood Hits	65
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LAMA5_HUMAN
θ value	0.0148317 (rank : 43)	NC score	0.130233 (rank : 51)
Query Neighborhood Hits	127	Target Neighborhood Hits	976	Shared Neighborhood Hits	85
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

PCSK5_MOUSE
θ value	0.0148317 (rank : 44)	NC score	0.157803 (rank : 48)
Query Neighborhood Hits	127	Target Neighborhood Hits	613	Shared Neighborhood Hits	92
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

MEGF9_HUMAN
θ value	0.0193708 (rank : 45)	NC score	0.119073 (rank : 54)
Query Neighborhood Hits	127	Target Neighborhood Hits	557	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

EDAR_MOUSE
θ value	0.0252991 (rank : 46)	NC score	0.205014 (rank : 47)
Query Neighborhood Hits	127	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

FGRL1_MOUSE
θ value	0.0252991 (rank : 47)	NC score	0.027868 (rank : 159)
Query Neighborhood Hits	127	Target Neighborhood Hits	325	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

FRAS1_HUMAN
θ value	0.0330416 (rank : 48)	NC score	0.109594 (rank : 57)
Query Neighborhood Hits	127	Target Neighborhood Hits	759	Shared Neighborhood Hits	82
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PCSK6_HUMAN
θ value	0.0431538 (rank : 49)	NC score	0.108643 (rank : 59)
Query Neighborhood Hits	127	Target Neighborhood Hits	298	Shared Neighborhood Hits	64
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

DLL4_HUMAN
θ value	0.0736092 (rank : 50)	NC score	0.067591 (rank : 104)
Query Neighborhood Hits	127	Target Neighborhood Hits	435	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

LAMC1_HUMAN
θ value	0.0736092 (rank : 51)	NC score	0.111041 (rank : 55)
Query Neighborhood Hits	127	Target Neighborhood Hits	922	Shared Neighborhood Hits	72
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TR19L_HUMAN
θ value	0.0736092 (rank : 52)	NC score	0.298941 (rank : 43)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

FURIN_MOUSE
θ value	0.0961366 (rank : 53)	NC score	0.063628 (rank : 112)
Query Neighborhood Hits	127	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

NOTC4_HUMAN
θ value	0.0961366 (rank : 54)	NC score	0.054528 (rank : 132)
Query Neighborhood Hits	127	Target Neighborhood Hits	905	Shared Neighborhood Hits	56
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NTNG2_MOUSE
θ value	0.0961366 (rank : 55)	NC score	0.081838 (rank : 82)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TEX14_MOUSE
θ value	0.0961366 (rank : 56)	NC score	0.010882 (rank : 181)
Query Neighborhood Hits	127	Target Neighborhood Hits	1333	Shared Neighborhood Hits	9
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TNR18_MOUSE
θ value	0.0961366 (rank : 57)	NC score	0.375368 (rank : 40)
Query Neighborhood Hits	127	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

EDAR_HUMAN
θ value	0.125558 (rank : 58)	NC score	0.207235 (rank : 46)
Query Neighborhood Hits	127	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

FGRL1_HUMAN
θ value	0.125558 (rank : 59)	NC score	0.024899 (rank : 162)
Query Neighborhood Hits	127	Target Neighborhood Hits	335	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

TR19L_MOUSE
θ value	0.125558 (rank : 60)	NC score	0.299658 (rank : 42)
Query Neighborhood Hits	127	Target Neighborhood Hits	85	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

LAMA5_MOUSE
θ value	0.163984 (rank : 61)	NC score	0.126880 (rank : 52)
Query Neighborhood Hits	127	Target Neighborhood Hits	828	Shared Neighborhood Hits	81
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC3_HUMAN
θ value	0.163984 (rank : 62)	NC score	0.130835 (rank : 50)
Query Neighborhood Hits	127	Target Neighborhood Hits	588	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

MUC1_HUMAN
θ value	0.163984 (rank : 63)	NC score	0.016052 (rank : 170)
Query Neighborhood Hits	127	Target Neighborhood Hits	975	Shared Neighborhood Hits	20
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

LAMC2_MOUSE
θ value	0.21417 (rank : 64)	NC score	0.124582 (rank : 53)
Query Neighborhood Hits	127	Target Neighborhood Hits	614	Shared Neighborhood Hits	80
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

MEGF8_HUMAN
θ value	0.279714 (rank : 65)	NC score	0.096096 (rank : 70)
Query Neighborhood Hits	127	Target Neighborhood Hits	528	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NOTC4_MOUSE
θ value	0.279714 (rank : 66)	NC score	0.054834 (rank : 131)
Query Neighborhood Hits	127	Target Neighborhood Hits	872	Shared Neighborhood Hits	58
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

FURIN_HUMAN
θ value	0.365318 (rank : 67)	NC score	0.064400 (rank : 109)
Query Neighborhood Hits	127	Target Neighborhood Hits	52	Shared Neighborhood Hits	10
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

GPC6A_HUMAN
θ value	0.62314 (rank : 68)	NC score	0.014529 (rank : 176)
Query Neighborhood Hits	127	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

SREC_HUMAN
θ value	0.62314 (rank : 69)	NC score	0.107430 (rank : 60)
Query Neighborhood Hits	127	Target Neighborhood Hits	645	Shared Neighborhood Hits	74
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

CIC_MOUSE
θ value	0.813845 (rank : 70)	NC score	0.022064 (rank : 163)
Query Neighborhood Hits	127	Target Neighborhood Hits	742	Shared Neighborhood Hits	17
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DLL4_MOUSE
θ value	0.813845 (rank : 71)	NC score	0.061956 (rank : 121)
Query Neighborhood Hits	127	Target Neighborhood Hits	440	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

ESM1_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.063069 (rank : 115)
Query Neighborhood Hits	127	Target Neighborhood Hits	110	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

TIF1B_HUMAN
θ value	0.813845 (rank : 73)	NC score	0.026180 (rank : 160)
Query Neighborhood Hits	127	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

AIRE_MOUSE
θ value	1.06291 (rank : 74)	NC score	0.021673 (rank : 165)
Query Neighborhood Hits	127	Target Neighborhood Hits	196	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

SIVA_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.035456 (rank : 153)
Query Neighborhood Hits	127	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	O54926, Q3U6J2, Q921I8, Q9CWL1, Q9R1Q0, Q9R1Q1	Gene names	Siva
Domain Architecture
Description	Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP).

SREC2_MOUSE
θ value	1.06291 (rank : 76)	NC score	0.096350 (rank : 69)
Query Neighborhood Hits	127	Target Neighborhood Hits	605	Shared Neighborhood Hits	69
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TIF1B_MOUSE
θ value	1.06291 (rank : 77)	NC score	0.024969 (rank : 161)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	8
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

USH2A_MOUSE
θ value	1.06291 (rank : 78)	NC score	0.094985 (rank : 71)
Query Neighborhood Hits	127	Target Neighborhood Hits	626	Shared Neighborhood Hits	75
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

TNR19_HUMAN
θ value	1.38821 (rank : 79)	NC score	0.234838 (rank : 45)
Query Neighborhood Hits	127	Target Neighborhood Hits	89	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

JARD2_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.015860 (rank : 171)
Query Neighborhood Hits	127	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

MEGF8_MOUSE
θ value	1.81305 (rank : 81)	NC score	0.084097 (rank : 80)
Query Neighborhood Hits	127	Target Neighborhood Hits	520	Shared Neighborhood Hits	59
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

DOT1L_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.021814 (rank : 164)
Query Neighborhood Hits	127	Target Neighborhood Hits	660	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

EPHB4_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.006875 (rank : 186)
Query Neighborhood Hits	127	Target Neighborhood Hits	1056	Shared Neighborhood Hits	39
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

FAM5B_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.014888 (rank : 175)
Query Neighborhood Hits	127	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

KR109_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.052999 (rank : 134)
Query Neighborhood Hits	127	Target Neighborhood Hits	226	Shared Neighborhood Hits	36
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

STON1_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.015736 (rank : 172)
Query Neighborhood Hits	127	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

TNR6A_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.031177 (rank : 157)
Query Neighborhood Hits	127	Target Neighborhood Hits	343	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ZPBP2_MOUSE
θ value	2.36792 (rank : 88)	NC score	0.040612 (rank : 151)
Query Neighborhood Hits	127	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q6X786, Q6X785, Q9DA91	Gene names	Zpbp2
Domain Architecture	No domain graphic available
Description	Zona pellucida-binding protein 2 precursor.

FHL2_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.015057 (rank : 174)
Query Neighborhood Hits	127	Target Neighborhood Hits	539	Shared Neighborhood Hits	20
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

FILA_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.012834 (rank : 178)
Query Neighborhood Hits	127	Target Neighborhood Hits	685	Shared Neighborhood Hits	9
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

KRA59_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.093880 (rank : 74)
Query Neighborhood Hits	127	Target Neighborhood Hits	310	Shared Neighborhood Hits	45
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMA3_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.099822 (rank : 65)
Query Neighborhood Hits	127	Target Neighborhood Hits	859	Shared Neighborhood Hits	79
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

NOTC2_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.047516 (rank : 148)
Query Neighborhood Hits	127	Target Neighborhood Hits	1113	Shared Neighborhood Hits	62
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PGBM_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.066184 (rank : 108)
Query Neighborhood Hits	127	Target Neighborhood Hits	1113	Shared Neighborhood Hits	73
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SLIT3_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.031546 (rank : 156)
Query Neighborhood Hits	127	Target Neighborhood Hits	682	Shared Neighborhood Hits	45
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

CBL_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.008714 (rank : 183)
Query Neighborhood Hits	127	Target Neighborhood Hits	426	Shared Neighborhood Hits	9
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CRIM1_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.062566 (rank : 118)
Query Neighborhood Hits	127	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KR104_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.064251 (rank : 111)
Query Neighborhood Hits	127	Target Neighborhood Hits	313	Shared Neighborhood Hits	42
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

LAMB1_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.093098 (rank : 75)
Query Neighborhood Hits	127	Target Neighborhood Hits	919	Shared Neighborhood Hits	75
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MLL2_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.019872 (rank : 167)
Query Neighborhood Hits	127	Target Neighborhood Hits	1788	Shared Neighborhood Hits	42
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PER3_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.010009 (rank : 182)
Query Neighborhood Hits	127	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

RGS3_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.007828 (rank : 184)
Query Neighborhood Hits	127	Target Neighborhood Hits	1621	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TSP1_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.032176 (rank : 154)
Query Neighborhood Hits	127	Target Neighborhood Hits	389	Shared Neighborhood Hits	47
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

VINEX_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.006402 (rank : 188)
Query Neighborhood Hits	127	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

FHL3_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.018053 (rank : 168)
Query Neighborhood Hits	127	Target Neighborhood Hits	354	Shared Neighborhood Hits	21
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

KR107_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.069613 (rank : 99)
Query Neighborhood Hits	127	Target Neighborhood Hits	330	Shared Neighborhood Hits	46
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

LAMA1_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.099978 (rank : 64)
Query Neighborhood Hits	127	Target Neighborhood Hits	838	Shared Neighborhood Hits	78
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LPP_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.011548 (rank : 180)
Query Neighborhood Hits	127	Target Neighborhood Hits	775	Shared Neighborhood Hits	19
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

TSP1_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.031971 (rank : 155)
Query Neighborhood Hits	127	Target Neighborhood Hits	396	Shared Neighborhood Hits	49
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

CNOT3_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.013691 (rank : 177)
Query Neighborhood Hits	127	Target Neighborhood Hits	425	Shared Neighborhood Hits	12
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

DLL1_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.058802 (rank : 124)
Query Neighborhood Hits	127	Target Neighborhood Hits	456	Shared Neighborhood Hits	54
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

LTB1L_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.042645 (rank : 150)
Query Neighborhood Hits	127	Target Neighborhood Hits	514	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MINT_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.005231 (rank : 189)
Query Neighborhood Hits	127	Target Neighborhood Hits	1514	Shared Neighborhood Hits	19
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NACAM_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.012818 (rank : 179)
Query Neighborhood Hits	127	Target Neighborhood Hits	1866	Shared Neighborhood Hits	28
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NOTC3_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.052538 (rank : 135)
Query Neighborhood Hits	127	Target Neighborhood Hits	1062	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FHL3_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.020528 (rank : 166)
Query Neighborhood Hits	127	Target Neighborhood Hits	424	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R059, Q9JLP5, Q9WUH3	Gene names	Fhl3
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

GP179_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.017539 (rank : 169)
Query Neighborhood Hits	127	Target Neighborhood Hits	372	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

KRA53_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.074085 (rank : 90)
Query Neighborhood Hits	127	Target Neighborhood Hits	331	Shared Neighborhood Hits	44
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

LAMC2_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.109724 (rank : 56)
Query Neighborhood Hits	127	Target Neighborhood Hits	715	Shared Neighborhood Hits	75
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LRP1_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.037463 (rank : 152)
Query Neighborhood Hits	127	Target Neighborhood Hits	617	Shared Neighborhood Hits	53
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LTBP4_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.047417 (rank : 149)
Query Neighborhood Hits	127	Target Neighborhood Hits	607	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MAML2_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.006827 (rank : 187)
Query Neighborhood Hits	127	Target Neighborhood Hits	360	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

NELL1_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.048852 (rank : 147)
Query Neighborhood Hits	127	Target Neighborhood Hits	451	Shared Neighborhood Hits	54
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

SLIT3_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.029816 (rank : 158)
Query Neighborhood Hits	127	Target Neighborhood Hits	700	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TCF20_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.007545 (rank : 185)
Query Neighborhood Hits	127	Target Neighborhood Hits	396	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TM108_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.015148 (rank : 173)
Query Neighborhood Hits	127	Target Neighborhood Hits	336	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

USH2A_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.087737 (rank : 79)
Query Neighborhood Hits	127	Target Neighborhood Hits	600	Shared Neighborhood Hits	71
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

AGRIN_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.063270 (rank : 114)
Query Neighborhood Hits	127	Target Neighborhood Hits	582	Shared Neighborhood Hits	55
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ATRN_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.050837 (rank : 142)
Query Neighborhood Hits	127	Target Neighborhood Hits	525	Shared Neighborhood Hits	47
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.052065 (rank : 136)
Query Neighborhood Hits	127	Target Neighborhood Hits	519	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CREL1_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.059219 (rank : 123)
Query Neighborhood Hits	127	Target Neighborhood Hits	441	Shared Neighborhood Hits	53
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.054980 (rank : 129)
Query Neighborhood Hits	127	Target Neighborhood Hits	524	Shared Neighborhood Hits	55
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

DLK_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.050956 (rank : 141)
Query Neighborhood Hits	127	Target Neighborhood Hits	401	Shared Neighborhood Hits	48
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.057924 (rank : 126)
Query Neighborhood Hits	127	Target Neighborhood Hits	455	Shared Neighborhood Hits	52
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

FRAS1_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.098039 (rank : 68)
Query Neighborhood Hits	127	Target Neighborhood Hits	747	Shared Neighborhood Hits	81
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

JAG1_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.050505 (rank : 145)
Query Neighborhood Hits	127	Target Neighborhood Hits	514	Shared Neighborhood Hits	50
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

KR101_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.062286 (rank : 119)
Query Neighborhood Hits	127	Target Neighborhood Hits	261	Shared Neighborhood Hits	42
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.051032 (rank : 140)
Query Neighborhood Hits	127	Target Neighborhood Hits	264	Shared Neighborhood Hits	41
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR106_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.057756 (rank : 127)
Query Neighborhood Hits	127	Target Neighborhood Hits	347	Shared Neighborhood Hits	49
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR510_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.057421 (rank : 128)
Query Neighborhood Hits	127	Target Neighborhood Hits	217	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.050123 (rank : 146)
Query Neighborhood Hits	127	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA51_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.075902 (rank : 88)
Query Neighborhood Hits	127	Target Neighborhood Hits	288	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.069637 (rank : 98)
Query Neighborhood Hits	127	Target Neighborhood Hits	236	Shared Neighborhood Hits	36
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA54_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.078050 (rank : 85)
Query Neighborhood Hits	127	Target Neighborhood Hits	270	Shared Neighborhood Hits	40
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.063606 (rank : 113)
Query Neighborhood Hits	127	Target Neighborhood Hits	257	Shared Neighborhood Hits	41
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.066330 (rank : 107)
Query Neighborhood Hits	127	Target Neighborhood Hits	207	Shared Neighborhood Hits	33
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.054863 (rank : 130)
Query Neighborhood Hits	127	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.067633 (rank : 103)
Query Neighborhood Hits	127	Target Neighborhood Hits	324	Shared Neighborhood Hits	42
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMA1_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.099482 (rank : 66)
Query Neighborhood Hits	127	Target Neighborhood Hits	804	Shared Neighborhood Hits	73
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.091854 (rank : 76)
Query Neighborhood Hits	127	Target Neighborhood Hits	1092	Shared Neighborhood Hits	77
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.082678 (rank : 81)
Query Neighborhood Hits	127	Target Neighborhood Hits	1198	Shared Neighborhood Hits	72
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.088655 (rank : 77)
Query Neighborhood Hits	127	Target Neighborhood Hits	760	Shared Neighborhood Hits	61
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.072289 (rank : 93)
Query Neighborhood Hits	127	Target Neighborhood Hits	708	Shared Neighborhood Hits	52
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.076365 (rank : 87)
Query Neighborhood Hits	127	Target Neighborhood Hits	584	Shared Neighborhood Hits	51
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.088404 (rank : 78)
Query Neighborhood Hits	127	Target Neighborhood Hits	1018	Shared Neighborhood Hits	70
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.094659 (rank : 72)
Query Neighborhood Hits	127	Target Neighborhood Hits	692	Shared Neighborhood Hits	68
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.098147 (rank : 67)
Query Neighborhood Hits	127	Target Neighborhood Hits	722	Shared Neighborhood Hits	70
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.079307 (rank : 84)
Query Neighborhood Hits	127	Target Neighborhood Hits	461	Shared Neighborhood Hits	49
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.076655 (rank : 86)
Query Neighborhood Hits	127	Target Neighborhood Hits	444	Shared Neighborhood Hits	53
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.103573 (rank : 63)
Query Neighborhood Hits	127	Target Neighborhood Hits	856	Shared Neighborhood Hits	69
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

MEGF6_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.079799 (rank : 83)
Query Neighborhood Hits	127	Target Neighborhood Hits	671	Shared Neighborhood Hits	71
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF9_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.107177 (rank : 61)
Query Neighborhood Hits	127	Target Neighborhood Hits	896	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MT3_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.062587 (rank : 117)
Query Neighborhood Hits	127	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

NET1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.062149 (rank : 120)
Query Neighborhood Hits	127	Target Neighborhood Hits	149	Shared Neighborhood Hits	35
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.062930 (rank : 116)
Query Neighborhood Hits	127	Target Neighborhood Hits	151	Shared Neighborhood Hits	36
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.068083 (rank : 102)
Query Neighborhood Hits	127	Target Neighborhood Hits	194	Shared Neighborhood Hits	42
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.067169 (rank : 105)
Query Neighborhood Hits	127	Target Neighborhood Hits	193	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET4_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.071166 (rank : 97)
Query Neighborhood Hits	127	Target Neighborhood Hits	191	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.067000 (rank : 106)
Query Neighborhood Hits	127	Target Neighborhood Hits	180	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NOTC3_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.050616 (rank : 144)
Query Neighborhood Hits	127	Target Neighborhood Hits	975	Shared Neighborhood Hits	57
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NTNG1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.071406 (rank : 95)
Query Neighborhood Hits	127	Target Neighborhood Hits	247	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.072100 (rank : 94)
Query Neighborhood Hits	127	Target Neighborhood Hits	246	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.071220 (rank : 96)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PCSK4_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.050619 (rank : 143)
Query Neighborhood Hits	127	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PCSK5_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.108682 (rank : 58)
Query Neighborhood Hits	127	Target Neighborhood Hits	291	Shared Neighborhood Hits	67
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PGBM_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.073204 (rank : 91)
Query Neighborhood Hits	127	Target Neighborhood Hits	1073	Shared Neighborhood Hits	79
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

RSPO1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.058675 (rank : 125)
Query Neighborhood Hits	127	Target Neighborhood Hits	101	Shared Neighborhood Hits	26
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO4_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.053386 (rank : 133)
Query Neighborhood Hits	127	Target Neighborhood Hits	110	Shared Neighborhood Hits	25
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

SCUB3_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.072872 (rank : 92)
Query Neighborhood Hits	127	Target Neighborhood Hits	428	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.074473 (rank : 89)
Query Neighborhood Hits	127	Target Neighborhood Hits	442	Shared Neighborhood Hits	69
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SSPO_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.051891 (rank : 138)
Query Neighborhood Hits	127	Target Neighborhood Hits	800	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STAB1_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.068975 (rank : 100)
Query Neighborhood Hits	127	Target Neighborhood Hits	546	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.068109 (rank : 101)
Query Neighborhood Hits	127	Target Neighborhood Hits	566	Shared Neighborhood Hits	67
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.061829 (rank : 122)
Query Neighborhood Hits	127	Target Neighborhood Hits	534	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.064358 (rank : 110)
Query Neighborhood Hits	127	Target Neighborhood Hits	528	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TNR19_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.294952 (rank : 44)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

WIF1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.051479 (rank : 139)
Query Neighborhood Hits	127	Target Neighborhood Hits	392	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.051923 (rank : 137)
Query Neighborhood Hits	127	Target Neighborhood Hits	393	Shared Neighborhood Hits	45
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ZAN_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.093921 (rank : 73)
Query Neighborhood Hits	127	Target Neighborhood Hits	808	Shared Neighborhood Hits	78
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

TNR1B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	127	Target Neighborhood Hits	127	Shared Neighborhood Hits	127
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1B_MOUSE
NC score	0.967517 (rank : 2)	θ value	3.87392e-144 (rank : 2)
Query Neighborhood Hits	127	Target Neighborhood Hits	123	Shared Neighborhood Hits	64
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR6B_HUMAN
NC score	0.880240 (rank : 3)	θ value	1.08979e-29 (rank : 3)
Query Neighborhood Hits	127	Target Neighborhood Hits	103	Shared Neighborhood Hits	57
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TR11B_HUMAN
NC score	0.863546 (rank : 4)	θ value	1.85889e-29 (rank : 4)
Query Neighborhood Hits	127	Target Neighborhood Hits	92	Shared Neighborhood Hits	59
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR3_HUMAN
NC score	0.855134 (rank : 5)	θ value	3.28125e-26 (rank : 6)
Query Neighborhood Hits	127	Target Neighborhood Hits	145	Shared Neighborhood Hits	71
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TR11B_MOUSE
NC score	0.853200 (rank : 6)	θ value	2.51237e-26 (rank : 5)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	58
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR5_HUMAN
NC score	0.843920 (rank : 7)	θ value	2.12685e-25 (rank : 8)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR14_HUMAN
NC score	0.836157 (rank : 8)	θ value	1.5773e-20 (rank : 13)
Query Neighborhood Hits	127	Target Neighborhood Hits	149	Shared Neighborhood Hits	71
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR3_MOUSE
NC score	0.834768 (rank : 9)	θ value	7.56453e-23 (rank : 10)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	64
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR5_MOUSE
NC score	0.822278 (rank : 10)	θ value	1.74391e-19 (rank : 14)
Query Neighborhood Hits	127	Target Neighborhood Hits	131	Shared Neighborhood Hits	66
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR11_MOUSE
NC score	0.798148 (rank : 11)	θ value	9.24701e-21 (rank : 12)
Query Neighborhood Hits	127	Target Neighborhood Hits	121	Shared Neighborhood Hits	63
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR11_HUMAN
NC score	0.796432 (rank : 12)	θ value	9.87957e-23 (rank : 11)
Query Neighborhood Hits	127	Target Neighborhood Hits	135	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR21_HUMAN
NC score	0.792048 (rank : 13)	θ value	1.24688e-25 (rank : 7)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	49
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
NC score	0.784331 (rank : 14)	θ value	8.08199e-25 (rank : 9)
Query Neighborhood Hits	127	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR26_MOUSE
NC score	0.748947 (rank : 15)	θ value	1.63604e-09 (rank : 24)
Query Neighborhood Hits	127	Target Neighborhood Hits	106	Shared Neighborhood Hits	54
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR4_HUMAN
NC score	0.741717 (rank : 16)	θ value	1.58096e-12 (rank : 16)
Query Neighborhood Hits	127	Target Neighborhood Hits	152	Shared Neighborhood Hits	70
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR4_MOUSE
NC score	0.734042 (rank : 17)	θ value	3.52202e-12 (rank : 17)
Query Neighborhood Hits	127	Target Neighborhood Hits	137	Shared Neighborhood Hits	73
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR22_MOUSE
NC score	0.730961 (rank : 18)	θ value	3.89403e-11 (rank : 19)
Query Neighborhood Hits	127	Target Neighborhood Hits	97	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
NC score	0.715485 (rank : 19)	θ value	6.87365e-08 (rank : 26)
Query Neighborhood Hits	127	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR9_MOUSE
NC score	0.700873 (rank : 20)	θ value	3.29651e-10 (rank : 22)
Query Neighborhood Hits	127	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR9_HUMAN
NC score	0.688560 (rank : 21)	θ value	1.25267e-09 (rank : 23)
Query Neighborhood Hits	127	Target Neighborhood Hits	166	Shared Neighborhood Hits	60
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR16_MOUSE
NC score	0.684591 (rank : 22)	θ value	1.47974e-10 (rank : 20)
Query Neighborhood Hits	127	Target Neighborhood Hits	178	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR8_HUMAN
NC score	0.683610 (rank : 23)	θ value	1.99529e-15 (rank : 15)
Query Neighborhood Hits	127	Target Neighborhood Hits	198	Shared Neighborhood Hits	67
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR16_HUMAN
NC score	0.678477 (rank : 24)	θ value	7.84624e-12 (rank : 18)
Query Neighborhood Hits	127	Target Neighborhood Hits	183	Shared Neighborhood Hits	70
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR1A_MOUSE
NC score	0.667973 (rank : 25)	θ value	1.9326e-10 (rank : 21)
Query Neighborhood Hits	127	Target Neighborhood Hits	131	Shared Neighborhood Hits	58
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR1A_HUMAN
NC score	0.646508 (rank : 26)	θ value	1.80886e-08 (rank : 25)
Query Neighborhood Hits	127	Target Neighborhood Hits	121	Shared Neighborhood Hits	55
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR6_MOUSE
NC score	0.646265 (rank : 27)	θ value	6.87365e-08 (rank : 27)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	55
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_HUMAN
NC score	0.613362 (rank : 28)	θ value	1.99992e-07 (rank : 29)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	52
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
NC score	0.573067 (rank : 29)	θ value	8.40245e-06 (rank : 32)
Query Neighborhood Hits	127	Target Neighborhood Hits	120	Shared Neighborhood Hits	59
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR25_HUMAN
NC score	0.562001 (rank : 30)	θ value	1.43324e-05 (rank : 33)
Query Neighborhood Hits	127	Target Neighborhood Hits	172	Shared Neighborhood Hits	64
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR8_MOUSE
NC score	0.553549 (rank : 31)	θ value	2.61198e-07 (rank : 30)
Query Neighborhood Hits	127	Target Neighborhood Hits	208	Shared Neighborhood Hits	52
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TR10B_HUMAN
NC score	0.530298 (rank : 32)	θ value	4.45536e-07 (rank : 31)
Query Neighborhood Hits	127	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TNR7_MOUSE
NC score	0.527101 (rank : 33)	θ value	0.00175202 (rank : 39)
Query Neighborhood Hits	127	Target Neighborhood Hits	112	Shared Neighborhood Hits	50
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TR10C_HUMAN
NC score	0.524541 (rank : 34)	θ value	1.87187e-05 (rank : 34)
Query Neighborhood Hits	127	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TR10A_HUMAN
NC score	0.500846 (rank : 35)	θ value	1.53129e-07 (rank : 28)
Query Neighborhood Hits	127	Target Neighborhood Hits	82	Shared Neighborhood Hits	47
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TNR18_HUMAN
NC score	0.489123 (rank : 36)	θ value	0.000270298 (rank : 37)
Query Neighborhood Hits	127	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TR10D_HUMAN
NC score	0.487613 (rank : 37)	θ value	1.87187e-05 (rank : 35)
Query Neighborhood Hits	127	Target Neighborhood Hits	62	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10B_MOUSE
NC score	0.464201 (rank : 38)	θ value	0.00390308 (rank : 40)
Query Neighborhood Hits	127	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR27_HUMAN
NC score	0.391896 (rank : 39)	θ value	3.19293e-05 (rank : 36)
Query Neighborhood Hits	127	Target Neighborhood Hits	69	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR18_MOUSE
NC score	0.375368 (rank : 40)	θ value	0.0961366 (rank : 57)
Query Neighborhood Hits	127	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR27_MOUSE
NC score	0.340032 (rank : 41)	θ value	0.000786445 (rank : 38)
Query Neighborhood Hits	127	Target Neighborhood Hits	61	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TR19L_MOUSE
NC score	0.299658 (rank : 42)	θ value	0.125558 (rank : 60)
Query Neighborhood Hits	127	Target Neighborhood Hits	85	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TR19L_HUMAN
NC score	0.298941 (rank : 43)	θ value	0.0736092 (rank : 52)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TNR19_MOUSE
NC score	0.294952 (rank : 44)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_HUMAN
NC score	0.234838 (rank : 45)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	127	Target Neighborhood Hits	89	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

EDAR_HUMAN
NC score	0.207235 (rank : 46)	θ value	0.125558 (rank : 58)
Query Neighborhood Hits	127	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

EDAR_MOUSE
NC score	0.205014 (rank : 47)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	127	Target Neighborhood Hits	66	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

PCSK5_MOUSE
NC score	0.157803 (rank : 48)	θ value	0.0148317 (rank : 44)
Query Neighborhood Hits	127	Target Neighborhood Hits	613	Shared Neighborhood Hits	92
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

LAMC3_MOUSE
NC score	0.140298 (rank : 49)	θ value	0.0113563 (rank : 41)
Query Neighborhood Hits	127	Target Neighborhood Hits	624	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_HUMAN
NC score	0.130835 (rank : 50)	θ value	0.163984 (rank : 62)
Query Neighborhood Hits	127	Target Neighborhood Hits	588	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_HUMAN
NC score	0.130233 (rank : 51)	θ value	0.0148317 (rank : 43)
Query Neighborhood Hits	127	Target Neighborhood Hits	976	Shared Neighborhood Hits	85
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
NC score	0.126880 (rank : 52)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	127	Target Neighborhood Hits	828	Shared Neighborhood Hits	81
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC2_MOUSE
NC score	0.124582 (rank : 53)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	127	Target Neighborhood Hits	614	Shared Neighborhood Hits	80
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

MEGF9_HUMAN
NC score	0.119073 (rank : 54)	θ value	0.0193708 (rank : 45)
Query Neighborhood Hits	127	Target Neighborhood Hits	557	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMC1_HUMAN
NC score	0.111041 (rank : 55)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	127	Target Neighborhood Hits	922	Shared Neighborhood Hits	72
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
NC score	0.109724 (rank : 56)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	127	Target Neighborhood Hits	715	Shared Neighborhood Hits	75
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

FRAS1_HUMAN
NC score	0.109594 (rank : 57)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	127	Target Neighborhood Hits	759	Shared Neighborhood Hits	82
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PCSK5_HUMAN
NC score	0.108682 (rank : 58)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	127	Target Neighborhood Hits	291	Shared Neighborhood Hits	67
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK6_HUMAN
NC score	0.108643 (rank : 59)	θ value	0.0431538 (rank : 49)
Query Neighborhood Hits	127	Target Neighborhood Hits	298	Shared Neighborhood Hits	64
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

SREC_HUMAN
NC score	0.107430 (rank : 60)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	127	Target Neighborhood Hits	645	Shared Neighborhood Hits	74
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

MEGF9_MOUSE
NC score	0.107177 (rank : 61)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	127	Target Neighborhood Hits	896	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SREC2_HUMAN
NC score	0.103666 (rank : 62)	θ value	0.0113563 (rank : 42)
Query Neighborhood Hits	127	Target Neighborhood Hits	645	Shared Neighborhood Hits	65
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LAMC1_MOUSE
NC score	0.103573 (rank : 63)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	127	Target Neighborhood Hits	856	Shared Neighborhood Hits	69
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA1_MOUSE
NC score	0.099978 (rank : 64)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	127	Target Neighborhood Hits	838	Shared Neighborhood Hits	78
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA3_MOUSE
NC score	0.099822 (rank : 65)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	127	Target Neighborhood Hits	859	Shared Neighborhood Hits	79
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA1_HUMAN
NC score	0.099482 (rank : 66)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	127	Target Neighborhood Hits	804	Shared Neighborhood Hits	73
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_MOUSE
NC score	0.098147 (rank : 67)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	127	Target Neighborhood Hits	722	Shared Neighborhood Hits	70
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

FRAS1_MOUSE
NC score	0.098039 (rank : 68)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	127	Target Neighborhood Hits	747	Shared Neighborhood Hits	81
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

SREC2_MOUSE
NC score	0.096350 (rank : 69)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	127	Target Neighborhood Hits	605	Shared Neighborhood Hits	69
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

MEGF8_HUMAN
NC score	0.096096 (rank : 70)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	127	Target Neighborhood Hits	528	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

USH2A_MOUSE
NC score	0.094985 (rank : 71)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	127	Target Neighborhood Hits	626	Shared Neighborhood Hits	75
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

LAMB2_HUMAN
NC score	0.094659 (rank : 72)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	127	Target Neighborhood Hits	692	Shared Neighborhood Hits	68
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

ZAN_MOUSE
NC score	0.093921 (rank : 73)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	127	Target Neighborhood Hits	808	Shared Neighborhood Hits	78
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KRA59_HUMAN
NC score	0.093880 (rank : 74)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	127	Target Neighborhood Hits	310	Shared Neighborhood Hits	45
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMB1_MOUSE
NC score	0.093098 (rank : 75)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	127	Target Neighborhood Hits	919	Shared Neighborhood Hits	75
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMA2_HUMAN
NC score	0.091854 (rank : 76)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	127	Target Neighborhood Hits	1092	Shared Neighborhood Hits	77
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
NC score	0.088655 (rank : 77)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	127	Target Neighborhood Hits	760	Shared Neighborhood Hits	61
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMB1_HUMAN
NC score	0.088404 (rank : 78)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	127	Target Neighborhood Hits	1018	Shared Neighborhood Hits	70
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

USH2A_HUMAN
NC score	0.087737 (rank : 79)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	127	Target Neighborhood Hits	600	Shared Neighborhood Hits	71
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

MEGF8_MOUSE
NC score	0.084097 (rank : 80)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	127	Target Neighborhood Hits	520	Shared Neighborhood Hits	59
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMA2_MOUSE
NC score	0.082678 (rank : 81)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	127	Target Neighborhood Hits	1198	Shared Neighborhood Hits	72
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NTNG2_MOUSE
NC score	0.081838 (rank : 82)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

MEGF6_HUMAN
NC score	0.079799 (rank : 83)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	127	Target Neighborhood Hits	671	Shared Neighborhood Hits	71
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LAMB3_HUMAN
NC score	0.079307 (rank : 84)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	127	Target Neighborhood Hits	461	Shared Neighborhood Hits	49
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

KRA54_HUMAN
NC score	0.078050 (rank : 85)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	127	Target Neighborhood Hits	270	Shared Neighborhood Hits	40
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LAMB3_MOUSE
NC score	0.076655 (rank : 86)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	127	Target Neighborhood Hits	444	Shared Neighborhood Hits	53
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMA4_MOUSE
NC score	0.076365 (rank : 87)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	127	Target Neighborhood Hits	584	Shared Neighborhood Hits	51
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KRA51_HUMAN
NC score	0.075902 (rank : 88)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	127	Target Neighborhood Hits	288	Shared Neighborhood Hits	42
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

SCUB3_MOUSE
NC score	0.074473 (rank : 89)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	127	Target Neighborhood Hits	442	Shared Neighborhood Hits	69
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

KRA53_HUMAN
NC score	0.074085 (rank : 90)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	127	Target Neighborhood Hits	331	Shared Neighborhood Hits	44
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

PGBM_MOUSE
NC score	0.073204 (rank : 91)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	127	Target Neighborhood Hits	1073	Shared Neighborhood Hits	79
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SCUB3_HUMAN
NC score	0.072872 (rank : 92)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	127	Target Neighborhood Hits	428	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMA4_HUMAN
NC score	0.072289 (rank : 93)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	127	Target Neighborhood Hits	708	Shared Neighborhood Hits	52
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

NTNG1_MOUSE
NC score	0.072100 (rank : 94)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	127	Target Neighborhood Hits	246	Shared Neighborhood Hits	43
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_HUMAN
NC score	0.071406 (rank : 95)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	127	Target Neighborhood Hits	247	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
NC score	0.071220 (rank : 96)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	39
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NET4_HUMAN
NC score	0.071166 (rank : 97)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	127	Target Neighborhood Hits	191	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

KRA52_HUMAN
NC score	0.069637 (rank : 98)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	127	Target Neighborhood Hits	236	Shared Neighborhood Hits	36
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KR107_HUMAN
NC score	0.069613 (rank : 99)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	127	Target Neighborhood Hits	330	Shared Neighborhood Hits	46
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

STAB1_HUMAN
NC score	0.068975 (rank : 100)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	127	Target Neighborhood Hits	546	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
NC score	0.068109 (rank : 101)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	127	Target Neighborhood Hits	566	Shared Neighborhood Hits	67
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

NET2_HUMAN
NC score	0.068083 (rank : 102)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	127	Target Neighborhood Hits	194	Shared Neighborhood Hits	42
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

KRA58_HUMAN
NC score	0.067633 (rank : 103)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	127	Target Neighborhood Hits	324	Shared Neighborhood Hits	42
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

DLL4_HUMAN
NC score	0.067591 (rank : 104)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	127	Target Neighborhood Hits	435	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NET2_MOUSE
NC score	0.067169 (rank : 105)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	127	Target Neighborhood Hits	193	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET4_MOUSE
NC score	0.067000 (rank : 106)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	127	Target Neighborhood Hits	180	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

KRA56_HUMAN
NC score	0.066330 (rank : 107)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	127	Target Neighborhood Hits	207	Shared Neighborhood Hits	33
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

PGBM_HUMAN
NC score	0.066184 (rank : 108)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	127	Target Neighborhood Hits	1113	Shared Neighborhood Hits	73
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

FURIN_HUMAN
NC score	0.064400 (rank : 109)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	127	Target Neighborhood Hits	52	Shared Neighborhood Hits	10
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

STAB2_MOUSE
NC score	0.064358 (rank : 110)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	127	Target Neighborhood Hits	528	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

KR104_HUMAN
NC score	0.064251 (rank : 111)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	127	Target Neighborhood Hits	313	Shared Neighborhood Hits	42
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

FURIN_MOUSE
NC score	0.063628 (rank : 112)	θ value	0.0961366 (rank : 53)
Query Neighborhood Hits	127	Target Neighborhood Hits	49	Shared Neighborhood Hits	8
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

KRA55_HUMAN
NC score	0.063606 (rank : 113)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	127	Target Neighborhood Hits	257	Shared Neighborhood Hits	41
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

AGRIN_HUMAN
NC score	0.063270 (rank : 114)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	127	Target Neighborhood Hits	582	Shared Neighborhood Hits	55
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

ESM1_HUMAN
NC score	0.063069 (rank : 115)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	127	Target Neighborhood Hits	110	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

NET1_MOUSE
NC score	0.062930 (rank : 116)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	127	Target Neighborhood Hits	151	Shared Neighborhood Hits	36
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

MT3_MOUSE
NC score	0.062587 (rank : 117)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	127	Target Neighborhood Hits	68	Shared Neighborhood Hits	17
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

CRIM1_HUMAN
NC score	0.062566 (rank : 118)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	127	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KR101_HUMAN
NC score	0.062286 (rank : 119)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	127	Target Neighborhood Hits	261	Shared Neighborhood Hits	42
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

NET1_HUMAN
NC score	0.062149 (rank : 120)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	127	Target Neighborhood Hits	149	Shared Neighborhood Hits	35
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

DLL4_MOUSE
NC score	0.061956 (rank : 121)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	127	Target Neighborhood Hits	440	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

STAB2_HUMAN
NC score	0.061829 (rank : 122)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	127	Target Neighborhood Hits	534	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

CREL1_HUMAN
NC score	0.059219 (rank : 123)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	127	Target Neighborhood Hits	441	Shared Neighborhood Hits	53
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

DLL1_MOUSE
NC score	0.058802 (rank : 124)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	127	Target Neighborhood Hits	456	Shared Neighborhood Hits	54
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

RSPO1_HUMAN
NC score	0.058675 (rank : 125)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	127	Target Neighborhood Hits	101	Shared Neighborhood Hits	26
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

DLL1_HUMAN
NC score	0.057924 (rank : 126)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	127	Target Neighborhood Hits	455	Shared Neighborhood Hits	52
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

KR106_HUMAN
NC score	0.057756 (rank : 127)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	127	Target Neighborhood Hits	347	Shared Neighborhood Hits	49
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR510_HUMAN
NC score	0.057421 (rank : 128)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	127	Target Neighborhood Hits	217	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

CREL1_MOUSE
NC score	0.054980 (rank : 129)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	127	Target Neighborhood Hits	524	Shared Neighborhood Hits	55
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

KRA57_HUMAN
NC score	0.054863 (rank : 130)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	127	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NOTC4_MOUSE
NC score	0.054834 (rank : 131)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	127	Target Neighborhood Hits	872	Shared Neighborhood Hits	58
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_HUMAN
NC score	0.054528 (rank : 132)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	127	Target Neighborhood Hits	905	Shared Neighborhood Hits	56
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

RSPO4_HUMAN
NC score	0.053386 (rank : 133)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	127	Target Neighborhood Hits	110	Shared Neighborhood Hits	25
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

KR109_HUMAN
NC score	0.052999 (rank : 134)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	127	Target Neighborhood Hits	226	Shared Neighborhood Hits	36
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

NOTC3_HUMAN
NC score	0.052538 (rank : 135)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	127	Target Neighborhood Hits	1062	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ATRN_MOUSE
NC score	0.052065 (rank : 136)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	127	Target Neighborhood Hits	519	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

WIF1_MOUSE
NC score	0.051923 (rank : 137)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	127	Target Neighborhood Hits	393	Shared Neighborhood Hits	45
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

SSPO_MOUSE
NC score	0.051891 (rank : 138)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	127	Target Neighborhood Hits	800	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

WIF1_HUMAN
NC score	0.051479 (rank : 139)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	127	Target Neighborhood Hits	392	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

KR102_HUMAN
NC score	0.051032 (rank : 140)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	127	Target Neighborhood Hits	264	Shared Neighborhood Hits	41
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

DLK_HUMAN
NC score	0.050956 (rank : 141)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	127	Target Neighborhood Hits	401	Shared Neighborhood Hits	48
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

ATRN_HUMAN
NC score	0.050837 (rank : 142)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	127	Target Neighborhood Hits	525	Shared Neighborhood Hits	47
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

PCSK4_HUMAN
NC score	0.050619 (rank : 143)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	127	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

NOTC3_MOUSE
NC score	0.050616 (rank : 144)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	127	Target Neighborhood Hits	975	Shared Neighborhood Hits	57
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

JAG1_HUMAN
NC score	0.050505 (rank : 145)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	127	Target Neighborhood Hits	514	Shared Neighborhood Hits	50
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

KR511_HUMAN
NC score	0.050123 (rank : 146)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	127	Target Neighborhood Hits	231	Shared Neighborhood Hits	31
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

NELL1_HUMAN
NC score	0.048852 (rank : 147)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	127	Target Neighborhood Hits	451	Shared Neighborhood Hits	54
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NOTC2_HUMAN
NC score	0.047516 (rank : 148)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	127	Target Neighborhood Hits	1113	Shared Neighborhood Hits	62
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LTBP4_MOUSE
NC score	0.047417 (rank : 149)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	127	Target Neighborhood Hits	607	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LTB1L_MOUSE
NC score	0.042645 (rank : 150)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	127	Target Neighborhood Hits	514	Shared Neighborhood Hits	56
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

ZPBP2_MOUSE
NC score	0.040612 (rank : 151)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	127	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q6X786, Q6X785, Q9DA91	Gene names	Zpbp2
Domain Architecture	No domain graphic available
Description	Zona pellucida-binding protein 2 precursor.

LRP1_HUMAN
NC score	0.037463 (rank : 152)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	127	Target Neighborhood Hits	617	Shared Neighborhood Hits	53
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

SIVA_MOUSE
NC score	0.035456 (rank : 153)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	127	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	O54926, Q3U6J2, Q921I8, Q9CWL1, Q9R1Q0, Q9R1Q1	Gene names	Siva
Domain Architecture
Description	Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP).

TSP1_HUMAN
NC score	0.032176 (rank : 154)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	127	Target Neighborhood Hits	389	Shared Neighborhood Hits	47
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
NC score	0.031971 (rank : 155)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	127	Target Neighborhood Hits	396	Shared Neighborhood Hits	49
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

SLIT3_HUMAN
NC score	0.031546 (rank : 156)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	127	Target Neighborhood Hits	682	Shared Neighborhood Hits	45
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

TNR6A_HUMAN
NC score	0.031177 (rank : 157)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	127	Target Neighborhood Hits	343	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

SLIT3_MOUSE
NC score	0.029816 (rank : 158)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	127	Target Neighborhood Hits	700	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

FGRL1_MOUSE
NC score	0.027868 (rank : 159)	θ value	0.0252991 (rank : 47)
Query Neighborhood Hits	127	Target Neighborhood Hits	325	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

TIF1B_HUMAN
NC score	0.026180 (rank : 160)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	127	Target Neighborhood Hits	312	Shared Neighborhood Hits	9
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.024969 (rank : 161)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	127	Target Neighborhood Hits	276	Shared Neighborhood Hits	8
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

FGRL1_HUMAN
NC score	0.024899 (rank : 162)	θ value	0.125558 (rank : 59)
Query Neighborhood Hits	127	Target Neighborhood Hits	335	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

CIC_MOUSE
NC score	0.022064 (rank : 163)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	127	Target Neighborhood Hits	742	Shared Neighborhood Hits	17
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DOT1L_HUMAN
NC score	0.021814 (rank : 164)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	127	Target Neighborhood Hits	660	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

AIRE_MOUSE
NC score	0.021673 (rank : 165)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	127	Target Neighborhood Hits	196	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

FHL3_MOUSE
NC score	0.020528 (rank : 166)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	127	Target Neighborhood Hits	424	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R059, Q9JLP5, Q9WUH3	Gene names	Fhl3
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

MLL2_HUMAN
NC score	0.019872 (rank : 167)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	127	Target Neighborhood Hits	1788	Shared Neighborhood Hits	42
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FHL3_HUMAN
NC score	0.018053 (rank : 168)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	127	Target Neighborhood Hits	354	Shared Neighborhood Hits	21
SwissProt Accessions	Q13643	Gene names	FHL3, SLIM2
Domain Architecture
Description	Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM- protein 2) (SLIM 2).

GP179_HUMAN
NC score	0.017539 (rank : 169)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	127	Target Neighborhood Hits	372	Shared Neighborhood Hits	22
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

MUC1_HUMAN
NC score	0.016052 (rank : 170)	θ value	0.163984 (rank : 63)
Query Neighborhood Hits	127	Target Neighborhood Hits	975	Shared Neighborhood Hits	20
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

JARD2_HUMAN
NC score	0.015860 (rank : 171)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	127	Target Neighborhood Hits	119	Shared Neighborhood Hits	4
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

STON1_HUMAN
NC score	0.015736 (rank : 172)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	127	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

TM108_MOUSE
NC score	0.015148 (rank : 173)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	127	Target Neighborhood Hits	336	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BHE4, Q80WR9	Gene names	Tmem108
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

FHL2_MOUSE
NC score	0.015057 (rank : 174)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	127	Target Neighborhood Hits	539	Shared Neighborhood Hits	20
SwissProt Accessions	O70433, P97448	Gene names	Fhl2
Domain Architecture
Description	Four and a half LIM domains protein 2 (FHL-2) (Skeletal muscle LIM- protein 3) (SLIM 3).

FAM5B_HUMAN
NC score	0.014888 (rank : 175)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	127	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	Q9C0B6, O95560, Q6ZWC1, Q7LCZ9, Q8N360	Gene names	FAM5B, BRINP2, DBCCR1L2, KIAA1747
Domain Architecture	No domain graphic available
Description	Protein FAM5B precursor (BMP/retinoic acid-inducible neural-specific protein 2) (DBCCR1-like protein 2).

GPC6A_HUMAN
NC score	0.014529 (rank : 176)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	127	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

CNOT3_HUMAN
NC score	0.013691 (rank : 177)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	127	Target Neighborhood Hits	425	Shared Neighborhood Hits	12
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

FILA_HUMAN
NC score	0.012834 (rank : 178)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	127	Target Neighborhood Hits	685	Shared Neighborhood Hits	9
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

NACAM_MOUSE
NC score	0.012818 (rank : 179)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	127	Target Neighborhood Hits	1866	Shared Neighborhood Hits	28
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

LPP_HUMAN
NC score	0.011548 (rank : 180)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	127	Target Neighborhood Hits	775	Shared Neighborhood Hits	19
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

TEX14_MOUSE
NC score	0.010882 (rank : 181)	θ value	0.0961366 (rank : 56)
Query Neighborhood Hits	127	Target Neighborhood Hits	1333	Shared Neighborhood Hits	9
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

PER3_MOUSE
NC score	0.010009 (rank : 182)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	127	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

CBL_MOUSE
NC score	0.008714 (rank : 183)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	127	Target Neighborhood Hits	426	Shared Neighborhood Hits	9
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

RGS3_MOUSE
NC score	0.007828 (rank : 184)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	127	Target Neighborhood Hits	1621	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TCF20_MOUSE
NC score	0.007545 (rank : 185)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	127	Target Neighborhood Hits	396	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

EPHB4_HUMAN
NC score	0.006875 (rank : 186)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	127	Target Neighborhood Hits	1056	Shared Neighborhood Hits	39
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

MAML2_HUMAN
NC score	0.006827 (rank : 187)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	127	Target Neighborhood Hits	360	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZL2, Q6AI23, Q6Y3A3, Q8IUL3, Q96JK6	Gene names	MAML2, KIAA1819
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 2 (Mam-2).

VINEX_MOUSE
NC score	0.006402 (rank : 188)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	127	Target Neighborhood Hits	286	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

MINT_MOUSE
NC score	0.005231 (rank : 189)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	127	Target Neighborhood Hits	1514	Shared Neighborhood Hits	19
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).