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Network neighborhood for query Sequence : TR11B_HUMAN

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TR11B_HUMAN
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TR11B_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR11B_MOUSE
θ value	0 (rank : 2)	NC score	0.988270 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR6B_HUMAN
θ value	8.59492e-43 (rank : 3)	NC score	0.910856 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR1B_HUMAN
θ value	1.85889e-29 (rank : 4)	NC score	0.863546 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	127	Shared Neighborhood Hits	59
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1B_MOUSE
θ value	2.42779e-29 (rank : 5)	NC score	0.859525 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	123	Shared Neighborhood Hits	52
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR21_MOUSE
θ value	3.28125e-26 (rank : 6)	NC score	0.790015 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	108	Shared Neighborhood Hits	46
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_HUMAN
θ value	1.62847e-25 (rank : 7)	NC score	0.802822 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	90	Shared Neighborhood Hits	54
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR5_MOUSE
θ value	6.84181e-24 (rank : 8)	NC score	0.831946 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	131	Shared Neighborhood Hits	67
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR11_MOUSE
θ value	4.9032e-22 (rank : 9)	NC score	0.790428 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	121	Shared Neighborhood Hits	58
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR5_HUMAN
θ value	4.9032e-22 (rank : 10)	NC score	0.829010 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR11_HUMAN
θ value	6.40375e-22 (rank : 11)	NC score	0.782876 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	135	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR3_HUMAN
θ value	5.07402e-19 (rank : 12)	NC score	0.815188 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR3_MOUSE
θ value	1.80466e-16 (rank : 13)	NC score	0.785895 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	113	Shared Neighborhood Hits	63
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR14_HUMAN
θ value	4.44505e-15 (rank : 14)	NC score	0.809350 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	149	Shared Neighborhood Hits	69
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR26_MOUSE
θ value	5.8054e-15 (rank : 15)	NC score	0.779302 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	106	Shared Neighborhood Hits	59
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR16_MOUSE
θ value	5.43371e-13 (rank : 16)	NC score	0.690718 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	178	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR16_HUMAN
θ value	1.2105e-12 (rank : 17)	NC score	0.685053 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	183	Shared Neighborhood Hits	64
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR9_MOUSE
θ value	2.0648e-12 (rank : 18)	NC score	0.712122 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR9_HUMAN
θ value	6.64225e-11 (rank : 19)	NC score	0.692413 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR1A_MOUSE
θ value	1.9326e-10 (rank : 20)	NC score	0.653094 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	131	Shared Neighborhood Hits	57
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR4_HUMAN
θ value	2.79066e-09 (rank : 21)	NC score	0.716777 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR8_HUMAN
θ value	2.79066e-09 (rank : 22)	NC score	0.621555 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	198	Shared Neighborhood Hits	56
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR6_HUMAN
θ value	4.76016e-09 (rank : 23)	NC score	0.623387 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	95	Shared Neighborhood Hits	52
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR1A_HUMAN
θ value	6.21693e-09 (rank : 24)	NC score	0.635915 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	121	Shared Neighborhood Hits	50
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR22_MOUSE
θ value	8.11959e-09 (rank : 25)	NC score	0.722419 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	97	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TR10C_HUMAN
θ value	2.36244e-08 (rank : 26)	NC score	0.559650 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	105	Shared Neighborhood Hits	40
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR23_MOUSE
θ value	3.08544e-08 (rank : 27)	NC score	0.710276 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	114	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TR10D_HUMAN
θ value	5.26297e-08 (rank : 28)	NC score	0.514390 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	62	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TNR4_MOUSE
θ value	8.97725e-08 (rank : 29)	NC score	0.695905 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	64
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TR10B_MOUSE
θ value	1.53129e-07 (rank : 30)	NC score	0.505734 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR10A_HUMAN
θ value	7.59969e-07 (rank : 31)	NC score	0.509269 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	82	Shared Neighborhood Hits	44
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TNR6_MOUSE
θ value	1.29631e-06 (rank : 32)	NC score	0.625626 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR18_HUMAN
θ value	4.92598e-06 (rank : 33)	NC score	0.526076 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TR10B_HUMAN
θ value	3.19293e-05 (rank : 34)	NC score	0.523202 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	71	Shared Neighborhood Hits	41
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR19L_HUMAN
θ value	4.1701e-05 (rank : 35)	NC score	0.345245 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	99	Shared Neighborhood Hits	36
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	4.1701e-05 (rank : 36)	NC score	0.353333 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TNR18_MOUSE
θ value	9.29e-05 (rank : 37)	NC score	0.425661 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR25_HUMAN
θ value	0.000158464 (rank : 38)	NC score	0.544787 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	172	Shared Neighborhood Hits	61
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR19_MOUSE
θ value	0.000602161 (rank : 39)	NC score	0.327962 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR8_MOUSE
θ value	0.000602161 (rank : 40)	NC score	0.496247 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	208	Shared Neighborhood Hits	45
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

PCSK5_MOUSE
θ value	0.00134147 (rank : 41)	NC score	0.140978 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	613	Shared Neighborhood Hits	73
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TNR7_HUMAN
θ value	0.00298849 (rank : 42)	NC score	0.543766 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	120	Shared Neighborhood Hits	59
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR27_HUMAN
θ value	0.00665767 (rank : 43)	NC score	0.351056 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

GOGA5_HUMAN
θ value	0.0252991 (rank : 44)	NC score	0.025542 (rank : 112)
Query Neighborhood Hits	92	Target Neighborhood Hits	1168	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

ZAN_MOUSE
θ value	0.0252991 (rank : 45)	NC score	0.096372 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	808	Shared Neighborhood Hits	57
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LAMC3_MOUSE
θ value	0.0431538 (rank : 46)	NC score	0.118262 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	624	Shared Neighborhood Hits	65
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

TNR7_MOUSE
θ value	0.0431538 (rank : 47)	NC score	0.503412 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	112	Shared Neighborhood Hits	53
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

RSPO1_HUMAN
θ value	0.0736092 (rank : 48)	NC score	0.107086 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

STAB2_HUMAN
θ value	0.0736092 (rank : 49)	NC score	0.063283 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	534	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LAMA3_MOUSE
θ value	0.125558 (rank : 50)	NC score	0.082609 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	859	Shared Neighborhood Hits	65
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

PCSK6_HUMAN
θ value	0.163984 (rank : 51)	NC score	0.094760 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	298	Shared Neighborhood Hits	54
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

TNR19_HUMAN
θ value	0.163984 (rank : 52)	NC score	0.248339 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

LAMC1_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.094546 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	922	Shared Neighborhood Hits	59
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

PGBM_MOUSE
θ value	0.365318 (rank : 54)	NC score	0.058604 (rank : 95)
Query Neighborhood Hits	92	Target Neighborhood Hits	1073	Shared Neighborhood Hits	59
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LAMA1_MOUSE
θ value	0.47712 (rank : 55)	NC score	0.086327 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	838	Shared Neighborhood Hits	64
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC3_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.108489 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	588	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

RSPO3_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.070106 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	128	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	0.47712 (rank : 58)	NC score	0.073200 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

CASR_MOUSE
θ value	0.62314 (rank : 59)	NC score	0.025642 (rank : 111)
Query Neighborhood Hits	92	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

FBLN1_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.031520 (rank : 109)
Query Neighborhood Hits	92	Target Neighborhood Hits	329	Shared Neighborhood Hits	37
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

VWF_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.049576 (rank : 107)
Query Neighborhood Hits	92	Target Neighborhood Hits	396	Shared Neighborhood Hits	34
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

CASR_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.021786 (rank : 114)
Query Neighborhood Hits	92	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

STAB2_MOUSE
θ value	0.813845 (rank : 63)	NC score	0.066728 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	528	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

LAMA2_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.080259 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	1092	Shared Neighborhood Hits	64
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MEGF8_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.072915 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	528	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

PCSK5_HUMAN
θ value	1.38821 (rank : 66)	NC score	0.099158 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	291	Shared Neighborhood Hits	57
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

ZNF25_HUMAN
θ value	1.81305 (rank : 67)	NC score	-0.003864 (rank : 126)
Query Neighborhood Hits	92	Target Neighborhood Hits	763	Shared Neighborhood Hits	3
SwissProt Accessions	P17030, Q8IYE3, Q8NDD6, Q96MU2	Gene names	ZNF25, KOX19
Domain Architecture
Description	Zinc finger protein 25 (Zinc finger protein KOX19).

FRAS1_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.088794 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	759	Shared Neighborhood Hits	66
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMC2_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.099276 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	614	Shared Neighborhood Hits	68
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

MEGF8_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.062265 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	520	Shared Neighborhood Hits	45
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

STAB1_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.066375 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	546	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

SYNE1_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.007585 (rank : 120)
Query Neighborhood Hits	92	Target Neighborhood Hits	1484	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

EPHAA_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.003268 (rank : 124)
Query Neighborhood Hits	92	Target Neighborhood Hits	960	Shared Neighborhood Hits	26
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

FATH_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.013037 (rank : 116)
Query Neighborhood Hits	92	Target Neighborhood Hits	570	Shared Neighborhood Hits	31
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

LAMC1_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.085778 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	856	Shared Neighborhood Hits	55
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

VWF_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.046923 (rank : 108)
Query Neighborhood Hits	92	Target Neighborhood Hits	381	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MEGF9_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.081173 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	557	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

PERF_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.014410 (rank : 115)
Query Neighborhood Hits	92	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

BPAEA_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.004715 (rank : 122)
Query Neighborhood Hits	92	Target Neighborhood Hits	1480	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

LAMC2_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.086056 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	715	Shared Neighborhood Hits	61
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

NELL2_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.029814 (rank : 110)
Query Neighborhood Hits	92	Target Neighborhood Hits	436	Shared Neighborhood Hits	36
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

TMOD1_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.011759 (rank : 117)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD1_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.011727 (rank : 118)
Query Neighborhood Hits	92	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

CPNE5_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.003707 (rank : 123)
Query Neighborhood Hits	92	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

FBLN1_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.024153 (rank : 113)
Query Neighborhood Hits	92	Target Neighborhood Hits	324	Shared Neighborhood Hits	34
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

LAMA5_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.095868 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	828	Shared Neighborhood Hits	68
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MEGF6_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.057825 (rank : 96)
Query Neighborhood Hits	92	Target Neighborhood Hits	671	Shared Neighborhood Hits	59
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

SENP2_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.008506 (rank : 119)
Query Neighborhood Hits	92	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

C8AP2_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.006171 (rank : 121)
Query Neighborhood Hits	92	Target Neighborhood Hits	405	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

LAMA5_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.098738 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	976	Shared Neighborhood Hits	71
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.072392 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	919	Shared Neighborhood Hits	61
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

TRI12_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.000462 (rank : 125)
Query Neighborhood Hits	92	Target Neighborhood Hits	387	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

EDAR_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.139573 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

EDAR_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.134848 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

FRAS1_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.080248 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	747	Shared Neighborhood Hits	64
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KRA51_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.053542 (rank : 103)
Query Neighborhood Hits	92	Target Neighborhood Hits	288	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.055929 (rank : 100)
Query Neighborhood Hits	92	Target Neighborhood Hits	236	Shared Neighborhood Hits	30
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.053586 (rank : 102)
Query Neighborhood Hits	92	Target Neighborhood Hits	331	Shared Neighborhood Hits	38
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.060431 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	270	Shared Neighborhood Hits	29
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA56_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.057301 (rank : 97)
Query Neighborhood Hits	92	Target Neighborhood Hits	207	Shared Neighborhood Hits	28
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA58_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.050962 (rank : 105)
Query Neighborhood Hits	92	Target Neighborhood Hits	324	Shared Neighborhood Hits	31
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.066386 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	310	Shared Neighborhood Hits	36
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMA1_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.079580 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	804	Shared Neighborhood Hits	59
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.067120 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	1198	Shared Neighborhood Hits	57
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.072233 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	760	Shared Neighborhood Hits	51
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.056188 (rank : 98)
Query Neighborhood Hits	92	Target Neighborhood Hits	708	Shared Neighborhood Hits	41
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.059691 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	584	Shared Neighborhood Hits	42
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.068876 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	1018	Shared Neighborhood Hits	55
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.066919 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	692	Shared Neighborhood Hits	54
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.071822 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	722	Shared Neighborhood Hits	56
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.053097 (rank : 104)
Query Neighborhood Hits	92	Target Neighborhood Hits	461	Shared Neighborhood Hits	38
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.050655 (rank : 106)
Query Neighborhood Hits	92	Target Neighborhood Hits	444	Shared Neighborhood Hits	37
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

MEGF9_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.078924 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	896	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MT3_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.055938 (rank : 99)
Query Neighborhood Hits	92	Target Neighborhood Hits	68	Shared Neighborhood Hits	15
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

RSPO1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.064987 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO4_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.072234 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	110	Shared Neighborhood Hits	24
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.061560 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	110	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SCUB3_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.062530 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	428	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.063857 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	442	Shared Neighborhood Hits	62
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SREC2_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.058899 (rank : 94)
Query Neighborhood Hits	92	Target Neighborhood Hits	645	Shared Neighborhood Hits	49
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.054694 (rank : 101)
Query Neighborhood Hits	92	Target Neighborhood Hits	605	Shared Neighborhood Hits	52
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.068304 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	645	Shared Neighborhood Hits	56
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.060961 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	566	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TNR27_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.289924 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

USH2A_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.059346 (rank : 93)
Query Neighborhood Hits	92	Target Neighborhood Hits	600	Shared Neighborhood Hits	55
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.063438 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	626	Shared Neighborhood Hits	55
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

Hits sorted by NC score

TR11B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR11B_MOUSE
NC score	0.988270 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	95	Shared Neighborhood Hits	73
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR6B_HUMAN
NC score	0.910856 (rank : 3)	θ value	8.59492e-43 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	103	Shared Neighborhood Hits	60
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR1B_HUMAN
NC score	0.863546 (rank : 4)	θ value	1.85889e-29 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	127	Shared Neighborhood Hits	59
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR1B_MOUSE
NC score	0.859525 (rank : 5)	θ value	2.42779e-29 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	123	Shared Neighborhood Hits	52
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR5_MOUSE
NC score	0.831946 (rank : 6)	θ value	6.84181e-24 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	131	Shared Neighborhood Hits	67
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR5_HUMAN
NC score	0.829010 (rank : 7)	θ value	4.9032e-22 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	102	Shared Neighborhood Hits	60
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR3_HUMAN
NC score	0.815188 (rank : 8)	θ value	5.07402e-19 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	145	Shared Neighborhood Hits	63
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR14_HUMAN
NC score	0.809350 (rank : 9)	θ value	4.44505e-15 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	149	Shared Neighborhood Hits	69
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR21_HUMAN
NC score	0.802822 (rank : 10)	θ value	1.62847e-25 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	90	Shared Neighborhood Hits	54
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR11_MOUSE
NC score	0.790428 (rank : 11)	θ value	4.9032e-22 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	121	Shared Neighborhood Hits	58
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR21_MOUSE
NC score	0.790015 (rank : 12)	θ value	3.28125e-26 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	108	Shared Neighborhood Hits	46
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR3_MOUSE
NC score	0.785895 (rank : 13)	θ value	1.80466e-16 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	113	Shared Neighborhood Hits	63
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR11_HUMAN
NC score	0.782876 (rank : 14)	θ value	6.40375e-22 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	135	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR26_MOUSE
NC score	0.779302 (rank : 15)	θ value	5.8054e-15 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	106	Shared Neighborhood Hits	59
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR22_MOUSE
NC score	0.722419 (rank : 16)	θ value	8.11959e-09 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	97	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR4_HUMAN
NC score	0.716777 (rank : 17)	θ value	2.79066e-09 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	152	Shared Neighborhood Hits	60
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR9_MOUSE
NC score	0.712122 (rank : 18)	θ value	2.0648e-12 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	65
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR23_MOUSE
NC score	0.710276 (rank : 19)	θ value	3.08544e-08 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	114	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR4_MOUSE
NC score	0.695905 (rank : 20)	θ value	8.97725e-08 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	64
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR9_HUMAN
NC score	0.692413 (rank : 21)	θ value	6.64225e-11 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR16_MOUSE
NC score	0.690718 (rank : 22)	θ value	5.43371e-13 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	178	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR16_HUMAN
NC score	0.685053 (rank : 23)	θ value	1.2105e-12 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	183	Shared Neighborhood Hits	64
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR1A_MOUSE
NC score	0.653094 (rank : 24)	θ value	1.9326e-10 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	131	Shared Neighborhood Hits	57
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR1A_HUMAN
NC score	0.635915 (rank : 25)	θ value	6.21693e-09 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	121	Shared Neighborhood Hits	50
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR6_MOUSE
NC score	0.625626 (rank : 26)	θ value	1.29631e-06 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_HUMAN
NC score	0.623387 (rank : 27)	θ value	4.76016e-09 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	95	Shared Neighborhood Hits	52
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR8_HUMAN
NC score	0.621555 (rank : 28)	θ value	2.79066e-09 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	198	Shared Neighborhood Hits	56
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TR10C_HUMAN
NC score	0.559650 (rank : 29)	θ value	2.36244e-08 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	105	Shared Neighborhood Hits	40
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR25_HUMAN
NC score	0.544787 (rank : 30)	θ value	0.000158464 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	172	Shared Neighborhood Hits	61
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR7_HUMAN
NC score	0.543766 (rank : 31)	θ value	0.00298849 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	120	Shared Neighborhood Hits	59
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR18_HUMAN
NC score	0.526076 (rank : 32)	θ value	4.92598e-06 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TR10B_HUMAN
NC score	0.523202 (rank : 33)	θ value	3.19293e-05 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	71	Shared Neighborhood Hits	41
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10D_HUMAN
NC score	0.514390 (rank : 34)	θ value	5.26297e-08 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	62	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10A_HUMAN
NC score	0.509269 (rank : 35)	θ value	7.59969e-07 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	82	Shared Neighborhood Hits	44
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TR10B_MOUSE
NC score	0.505734 (rank : 36)	θ value	1.53129e-07 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR7_MOUSE
NC score	0.503412 (rank : 37)	θ value	0.0431538 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	112	Shared Neighborhood Hits	53
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR8_MOUSE
NC score	0.496247 (rank : 38)	θ value	0.000602161 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	208	Shared Neighborhood Hits	45
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR18_MOUSE
NC score	0.425661 (rank : 39)	θ value	9.29e-05 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TR19L_MOUSE
NC score	0.353333 (rank : 40)	θ value	4.1701e-05 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TNR27_HUMAN
NC score	0.351056 (rank : 41)	θ value	0.00665767 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TR19L_HUMAN
NC score	0.345245 (rank : 42)	θ value	4.1701e-05 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	99	Shared Neighborhood Hits	36
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TNR19_MOUSE
NC score	0.327962 (rank : 43)	θ value	0.000602161 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR27_MOUSE
NC score	0.289924 (rank : 44)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	92	Target Neighborhood Hits	61	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR19_HUMAN
NC score	0.248339 (rank : 45)	θ value	0.163984 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

PCSK5_MOUSE
NC score	0.140978 (rank : 46)	θ value	0.00134147 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	613	Shared Neighborhood Hits	73
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

EDAR_HUMAN
NC score	0.139573 (rank : 47)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	92	Target Neighborhood Hits	84	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

EDAR_MOUSE
NC score	0.134848 (rank : 48)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	92	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

LAMC3_MOUSE
NC score	0.118262 (rank : 49)	θ value	0.0431538 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	624	Shared Neighborhood Hits	65
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_HUMAN
NC score	0.108489 (rank : 50)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	588	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

RSPO1_HUMAN
NC score	0.107086 (rank : 51)	θ value	0.0736092 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	101	Shared Neighborhood Hits	22
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

LAMC2_MOUSE
NC score	0.099276 (rank : 52)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	614	Shared Neighborhood Hits	68
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

PCSK5_HUMAN
NC score	0.099158 (rank : 53)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	291	Shared Neighborhood Hits	57
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

LAMA5_HUMAN
NC score	0.098738 (rank : 54)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	976	Shared Neighborhood Hits	71
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

ZAN_MOUSE
NC score	0.096372 (rank : 55)	θ value	0.0252991 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	808	Shared Neighborhood Hits	57
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LAMA5_MOUSE
NC score	0.095868 (rank : 56)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	828	Shared Neighborhood Hits	68
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

PCSK6_HUMAN
NC score	0.094760 (rank : 57)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	298	Shared Neighborhood Hits	54
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

LAMC1_HUMAN
NC score	0.094546 (rank : 58)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	922	Shared Neighborhood Hits	59
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

FRAS1_HUMAN
NC score	0.088794 (rank : 59)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	759	Shared Neighborhood Hits	66
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA1_MOUSE
NC score	0.086327 (rank : 60)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	838	Shared Neighborhood Hits	64
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC2_HUMAN
NC score	0.086056 (rank : 61)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	715	Shared Neighborhood Hits	61
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC1_MOUSE
NC score	0.085778 (rank : 62)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	856	Shared Neighborhood Hits	55
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA3_MOUSE
NC score	0.082609 (rank : 63)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	859	Shared Neighborhood Hits	65
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

MEGF9_HUMAN
NC score	0.081173 (rank : 64)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	557	Shared Neighborhood Hits	51
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMA2_HUMAN
NC score	0.080259 (rank : 65)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	1092	Shared Neighborhood Hits	64
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

FRAS1_MOUSE
NC score	0.080248 (rank : 66)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	92	Target Neighborhood Hits	747	Shared Neighborhood Hits	64
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA1_HUMAN
NC score	0.079580 (rank : 67)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	92	Target Neighborhood Hits	804	Shared Neighborhood Hits	59
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MEGF9_MOUSE
NC score	0.078924 (rank : 68)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	92	Target Neighborhood Hits	896	Shared Neighborhood Hits	54
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

RSPO3_MOUSE
NC score	0.073200 (rank : 69)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

MEGF8_HUMAN
NC score	0.072915 (rank : 70)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	528	Shared Neighborhood Hits	49
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMB1_MOUSE
NC score	0.072392 (rank : 71)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	919	Shared Neighborhood Hits	61
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

RSPO4_HUMAN
NC score	0.072234 (rank : 72)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	92	Target Neighborhood Hits	110	Shared Neighborhood Hits	24
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

LAMA3_HUMAN
NC score	0.072233 (rank : 73)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	92	Target Neighborhood Hits	760	Shared Neighborhood Hits	51
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMB2_MOUSE
NC score	0.071822 (rank : 74)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	92	Target Neighborhood Hits	722	Shared Neighborhood Hits	56
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

RSPO3_HUMAN
NC score	0.070106 (rank : 75)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	128	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

LAMB1_HUMAN
NC score	0.068876 (rank : 76)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	92	Target Neighborhood Hits	1018	Shared Neighborhood Hits	55
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SREC_HUMAN
NC score	0.068304 (rank : 77)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	92	Target Neighborhood Hits	645	Shared Neighborhood Hits	56
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LAMA2_MOUSE
NC score	0.067120 (rank : 78)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	92	Target Neighborhood Hits	1198	Shared Neighborhood Hits	57
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB2_HUMAN
NC score	0.066919 (rank : 79)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	92	Target Neighborhood Hits	692	Shared Neighborhood Hits	54
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

STAB2_MOUSE
NC score	0.066728 (rank : 80)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	528	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

KRA59_HUMAN
NC score	0.066386 (rank : 81)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	92	Target Neighborhood Hits	310	Shared Neighborhood Hits	36
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

STAB1_HUMAN
NC score	0.066375 (rank : 82)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	546	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

RSPO1_MOUSE
NC score	0.064987 (rank : 83)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

SCUB3_MOUSE
NC score	0.063857 (rank : 84)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	92	Target Neighborhood Hits	442	Shared Neighborhood Hits	62
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

USH2A_MOUSE
NC score	0.063438 (rank : 85)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	92	Target Neighborhood Hits	626	Shared Neighborhood Hits	55
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

STAB2_HUMAN
NC score	0.063283 (rank : 86)	θ value	0.0736092 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	534	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SCUB3_HUMAN
NC score	0.062530 (rank : 87)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	92	Target Neighborhood Hits	428	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

MEGF8_MOUSE
NC score	0.062265 (rank : 88)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	520	Shared Neighborhood Hits	45
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

RSPO4_MOUSE
NC score	0.061560 (rank : 89)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	92	Target Neighborhood Hits	110	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

STAB1_MOUSE
NC score	0.060961 (rank : 90)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	92	Target Neighborhood Hits	566	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

KRA54_HUMAN
NC score	0.060431 (rank : 91)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	92	Target Neighborhood Hits	270	Shared Neighborhood Hits	29
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LAMA4_MOUSE
NC score	0.059691 (rank : 92)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	92	Target Neighborhood Hits	584	Shared Neighborhood Hits	42
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

USH2A_HUMAN
NC score	0.059346 (rank : 93)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	92	Target Neighborhood Hits	600	Shared Neighborhood Hits	55
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

SREC2_HUMAN
NC score	0.058899 (rank : 94)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	92	Target Neighborhood Hits	645	Shared Neighborhood Hits	49
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

PGBM_MOUSE
NC score	0.058604 (rank : 95)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	1073	Shared Neighborhood Hits	59
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MEGF6_HUMAN
NC score	0.057825 (rank : 96)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	671	Shared Neighborhood Hits	59
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KRA56_HUMAN
NC score	0.057301 (rank : 97)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	92	Target Neighborhood Hits	207	Shared Neighborhood Hits	28
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LAMA4_HUMAN
NC score	0.056188 (rank : 98)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	92	Target Neighborhood Hits	708	Shared Neighborhood Hits	41
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MT3_MOUSE
NC score	0.055938 (rank : 99)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	92	Target Neighborhood Hits	68	Shared Neighborhood Hits	15
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

KRA52_HUMAN
NC score	0.055929 (rank : 100)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	92	Target Neighborhood Hits	236	Shared Neighborhood Hits	30
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

SREC2_MOUSE
NC score	0.054694 (rank : 101)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	92	Target Neighborhood Hits	605	Shared Neighborhood Hits	52
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KRA53_HUMAN
NC score	0.053586 (rank : 102)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	92	Target Neighborhood Hits	331	Shared Neighborhood Hits	38
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA51_HUMAN
NC score	0.053542 (rank : 103)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	92	Target Neighborhood Hits	288	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LAMB3_HUMAN
NC score	0.053097 (rank : 104)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	92	Target Neighborhood Hits	461	Shared Neighborhood Hits	38
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

KRA58_HUMAN
NC score	0.050962 (rank : 105)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	92	Target Neighborhood Hits	324	Shared Neighborhood Hits	31
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMB3_MOUSE
NC score	0.050655 (rank : 106)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	92	Target Neighborhood Hits	444	Shared Neighborhood Hits	37
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

VWF_HUMAN
NC score	0.049576 (rank : 107)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	396	Shared Neighborhood Hits	34
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
NC score	0.046923 (rank : 108)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	381	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

FBLN1_MOUSE
NC score	0.031520 (rank : 109)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	329	Shared Neighborhood Hits	37
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

NELL2_MOUSE
NC score	0.029814 (rank : 110)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	436	Shared Neighborhood Hits	36
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

CASR_MOUSE
NC score	0.025642 (rank : 111)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	72	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

GOGA5_HUMAN
NC score	0.025542 (rank : 112)	θ value	0.0252991 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	1168	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

FBLN1_HUMAN
NC score	0.024153 (rank : 113)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	324	Shared Neighborhood Hits	34
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

CASR_HUMAN
NC score	0.021786 (rank : 114)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

PERF_MOUSE
NC score	0.014410 (rank : 115)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	P10820	Gene names	Prf1, Pfp
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (Cytolysin).

FATH_HUMAN
NC score	0.013037 (rank : 116)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	570	Shared Neighborhood Hits	31
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TMOD1_HUMAN
NC score	0.011759 (rank : 117)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	P28289, Q9BUF1	Gene names	TMOD1, TMOD
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

TMOD1_MOUSE
NC score	0.011727 (rank : 118)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P49813, Q9ERR9	Gene names	Tmod1, Tmod
Domain Architecture
Description	Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod).

SENP2_MOUSE
NC score	0.008506 (rank : 119)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SYNE1_HUMAN
NC score	0.007585 (rank : 120)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	1484	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

C8AP2_MOUSE
NC score	0.006171 (rank : 121)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	405	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

BPAEA_MOUSE
NC score	0.004715 (rank : 122)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	1480	Shared Neighborhood Hits	17
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CPNE5_HUMAN
NC score	0.003707 (rank : 123)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCH3	Gene names	CPNE5, KIAA1599
Domain Architecture
Description	Copine-5 (Copine V).

EPHAA_HUMAN
NC score	0.003268 (rank : 124)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	960	Shared Neighborhood Hits	26
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

TRI12_MOUSE
NC score	0.000462 (rank : 125)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	387	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

ZNF25_HUMAN
NC score	-0.003864 (rank : 126)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	763	Shared Neighborhood Hits	3
SwissProt Accessions	P17030, Q8IYE3, Q8NDD6, Q96MU2	Gene names	ZNF25, KOX19
Domain Architecture
Description	Zinc finger protein 25 (Zinc finger protein KOX19).