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Network neighborhood for query Sequence : TNR6_HUMAN

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TNR6_HUMAN
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TNR6_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	95
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	2.38869e-85 (rank : 2)	NC score	0.934716 (rank : 2)
Query Neighborhood Hits	95	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR23_MOUSE
θ value	3.18553e-13 (rank : 3)	NC score	0.733317 (rank : 5)
Query Neighborhood Hits	95	Target Neighborhood Hits	114	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR26_MOUSE
θ value	6.00763e-12 (rank : 4)	NC score	0.757756 (rank : 3)
Query Neighborhood Hits	95	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TR10B_HUMAN
θ value	1.74796e-11 (rank : 5)	NC score	0.633588 (rank : 15)
Query Neighborhood Hits	95	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TNR14_HUMAN
θ value	2.28291e-11 (rank : 6)	NC score	0.693876 (rank : 6)
Query Neighborhood Hits	95	Target Neighborhood Hits	149	Shared Neighborhood Hits	59
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR22_MOUSE
θ value	2.28291e-11 (rank : 7)	NC score	0.743842 (rank : 4)
Query Neighborhood Hits	95	Target Neighborhood Hits	97	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR3_HUMAN
θ value	2.28291e-11 (rank : 8)	NC score	0.644767 (rank : 14)
Query Neighborhood Hits	95	Target Neighborhood Hits	145	Shared Neighborhood Hits	54
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR5_MOUSE
θ value	2.98157e-11 (rank : 9)	NC score	0.646841 (rank : 11)
Query Neighborhood Hits	95	Target Neighborhood Hits	131	Shared Neighborhood Hits	53
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR7_MOUSE
θ value	5.08577e-11 (rank : 10)	NC score	0.653065 (rank : 9)
Query Neighborhood Hits	95	Target Neighborhood Hits	112	Shared Neighborhood Hits	53
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TR10A_HUMAN
θ value	8.67504e-11 (rank : 11)	NC score	0.611339 (rank : 23)
Query Neighborhood Hits	95	Target Neighborhood Hits	82	Shared Neighborhood Hits	42
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TNR25_HUMAN
θ value	1.47974e-10 (rank : 12)	NC score	0.625690 (rank : 16)
Query Neighborhood Hits	95	Target Neighborhood Hits	172	Shared Neighborhood Hits	56
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR7_HUMAN
θ value	2.52405e-10 (rank : 13)	NC score	0.674071 (rank : 7)
Query Neighborhood Hits	95	Target Neighborhood Hits	120	Shared Neighborhood Hits	58
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TR10B_MOUSE
θ value	3.29651e-10 (rank : 14)	NC score	0.654440 (rank : 8)
Query Neighborhood Hits	95	Target Neighborhood Hits	76	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR10D_HUMAN
θ value	4.30538e-10 (rank : 15)	NC score	0.619901 (rank : 19)
Query Neighborhood Hits	95	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10C_HUMAN
θ value	7.34386e-10 (rank : 16)	NC score	0.649953 (rank : 10)
Query Neighborhood Hits	95	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR5_HUMAN
θ value	9.59137e-10 (rank : 17)	NC score	0.646818 (rank : 12)
Query Neighborhood Hits	95	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TR11B_HUMAN
θ value	4.76016e-09 (rank : 18)	NC score	0.623387 (rank : 18)
Query Neighborhood Hits	95	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR11B_MOUSE
θ value	1.38499e-08 (rank : 19)	NC score	0.617618 (rank : 21)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	50
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR4_MOUSE
θ value	1.17247e-07 (rank : 20)	NC score	0.646514 (rank : 13)
Query Neighborhood Hits	95	Target Neighborhood Hits	137	Shared Neighborhood Hits	58
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR1B_HUMAN
θ value	1.99992e-07 (rank : 21)	NC score	0.613362 (rank : 22)
Query Neighborhood Hits	95	Target Neighborhood Hits	127	Shared Neighborhood Hits	52
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR16_HUMAN
θ value	2.61198e-07 (rank : 22)	NC score	0.571425 (rank : 27)
Query Neighborhood Hits	95	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR11_HUMAN
θ value	5.81887e-07 (rank : 23)	NC score	0.558339 (rank : 29)
Query Neighborhood Hits	95	Target Neighborhood Hits	135	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR6B_HUMAN
θ value	9.92553e-07 (rank : 24)	NC score	0.603930 (rank : 24)
Query Neighborhood Hits	95	Target Neighborhood Hits	103	Shared Neighborhood Hits	49
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR3_MOUSE
θ value	1.69304e-06 (rank : 25)	NC score	0.597225 (rank : 26)
Query Neighborhood Hits	95	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR1A_MOUSE
θ value	8.40245e-06 (rank : 26)	NC score	0.618694 (rank : 20)
Query Neighborhood Hits	95	Target Neighborhood Hits	131	Shared Neighborhood Hits	52
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR11_MOUSE
θ value	1.09739e-05 (rank : 27)	NC score	0.553332 (rank : 30)
Query Neighborhood Hits	95	Target Neighborhood Hits	121	Shared Neighborhood Hits	52
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR1A_HUMAN
θ value	3.19293e-05 (rank : 28)	NC score	0.624415 (rank : 17)
Query Neighborhood Hits	95	Target Neighborhood Hits	121	Shared Neighborhood Hits	49
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR4_HUMAN
θ value	7.1131e-05 (rank : 29)	NC score	0.603228 (rank : 25)
Query Neighborhood Hits	95	Target Neighborhood Hits	152	Shared Neighborhood Hits	54
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR1B_MOUSE
θ value	0.00035302 (rank : 30)	NC score	0.568095 (rank : 28)
Query Neighborhood Hits	95	Target Neighborhood Hits	123	Shared Neighborhood Hits	47
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR8_HUMAN
θ value	0.00509761 (rank : 31)	NC score	0.480995 (rank : 32)
Query Neighborhood Hits	95	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

STAB2_HUMAN
θ value	0.0736092 (rank : 32)	NC score	0.085757 (rank : 74)
Query Neighborhood Hits	95	Target Neighborhood Hits	534	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LAMA4_HUMAN
θ value	0.163984 (rank : 33)	NC score	0.079769 (rank : 81)
Query Neighborhood Hits	95	Target Neighborhood Hits	708	Shared Neighborhood Hits	49
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TNR9_HUMAN
θ value	0.163984 (rank : 34)	NC score	0.438431 (rank : 34)
Query Neighborhood Hits	95	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

V2RX_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.026888 (rank : 176)
Query Neighborhood Hits	95	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

FBLN1_MOUSE
θ value	0.21417 (rank : 36)	NC score	0.057997 (rank : 124)
Query Neighborhood Hits	95	Target Neighborhood Hits	329	Shared Neighborhood Hits	47
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LAMC1_MOUSE
θ value	0.21417 (rank : 37)	NC score	0.095721 (rank : 63)
Query Neighborhood Hits	95	Target Neighborhood Hits	856	Shared Neighborhood Hits	66
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

PCSK5_HUMAN
θ value	0.21417 (rank : 38)	NC score	0.101916 (rank : 53)
Query Neighborhood Hits	95	Target Neighborhood Hits	291	Shared Neighborhood Hits	62
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

RIPK1_MOUSE
θ value	0.21417 (rank : 39)	NC score	0.014513 (rank : 182)
Query Neighborhood Hits	95	Target Neighborhood Hits	874	Shared Neighborhood Hits	10
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

MATN2_MOUSE
θ value	0.279714 (rank : 40)	NC score	0.057786 (rank : 125)
Query Neighborhood Hits	95	Target Neighborhood Hits	356	Shared Neighborhood Hits	47
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

NELL1_HUMAN
θ value	0.365318 (rank : 41)	NC score	0.068328 (rank : 94)
Query Neighborhood Hits	95	Target Neighborhood Hits	451	Shared Neighborhood Hits	50
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

TNR19_MOUSE
θ value	0.365318 (rank : 42)	NC score	0.235285 (rank : 39)
Query Neighborhood Hits	95	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

EMR4_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.020687 (rank : 178)
Query Neighborhood Hits	95	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

LAMA5_MOUSE
θ value	0.62314 (rank : 44)	NC score	0.111422 (rank : 50)
Query Neighborhood Hits	95	Target Neighborhood Hits	828	Shared Neighborhood Hits	70
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

RIPK1_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.010923 (rank : 186)
Query Neighborhood Hits	95	Target Neighborhood Hits	891	Shared Neighborhood Hits	12
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

SREC_HUMAN
θ value	0.62314 (rank : 46)	NC score	0.098964 (rank : 57)
Query Neighborhood Hits	95	Target Neighborhood Hits	645	Shared Neighborhood Hits	62
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_HUMAN
θ value	0.62314 (rank : 47)	NC score	0.096824 (rank : 61)
Query Neighborhood Hits	95	Target Neighborhood Hits	546	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

FRAS1_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.102657 (rank : 52)
Query Neighborhood Hits	95	Target Neighborhood Hits	759	Shared Neighborhood Hits	68
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	0.813845 (rank : 49)	NC score	0.098771 (rank : 58)
Query Neighborhood Hits	95	Target Neighborhood Hits	747	Shared Neighborhood Hits	66
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMC1_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.099512 (rank : 56)
Query Neighborhood Hits	95	Target Neighborhood Hits	922	Shared Neighborhood Hits	68
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

MT1M_HUMAN
θ value	0.813845 (rank : 51)	NC score	0.068487 (rank : 93)
Query Neighborhood Hits	95	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

NOTC1_HUMAN
θ value	0.813845 (rank : 52)	NC score	0.057331 (rank : 126)
Query Neighborhood Hits	95	Target Neighborhood Hits	906	Shared Neighborhood Hits	48
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

LAMA1_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.097735 (rank : 59)
Query Neighborhood Hits	95	Target Neighborhood Hits	804	Shared Neighborhood Hits	65
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

SREC2_HUMAN
θ value	1.06291 (rank : 54)	NC score	0.095836 (rank : 62)
Query Neighborhood Hits	95	Target Neighborhood Hits	645	Shared Neighborhood Hits	54
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

STAB1_MOUSE
θ value	1.06291 (rank : 55)	NC score	0.089463 (rank : 69)
Query Neighborhood Hits	95	Target Neighborhood Hits	566	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

ABLM2_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.017662 (rank : 179)
Query Neighborhood Hits	95	Target Neighborhood Hits	306	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BL65, Q6H8P8, Q80WK6, Q8BUT1, Q8BXI7	Gene names	Ablim2
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

NOTC1_MOUSE
θ value	1.38821 (rank : 57)	NC score	0.058151 (rank : 122)
Query Neighborhood Hits	95	Target Neighborhood Hits	916	Shared Neighborhood Hits	47
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ABLM2_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.016678 (rank : 180)
Query Neighborhood Hits	95	Target Neighborhood Hits	317	Shared Neighborhood Hits	5
SwissProt Accessions	Q6H8Q1, Q6H8Q0, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7	Gene names	ABLIM2, KIAA1808
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

COGA1_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.014271 (rank : 183)
Query Neighborhood Hits	95	Target Neighborhood Hits	345	Shared Neighborhood Hits	10
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

LAMA5_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.118718 (rank : 47)
Query Neighborhood Hits	95	Target Neighborhood Hits	976	Shared Neighborhood Hits	71
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC2_MOUSE
θ value	1.81305 (rank : 61)	NC score	0.104127 (rank : 51)
Query Neighborhood Hits	95	Target Neighborhood Hits	614	Shared Neighborhood Hits	69
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

MKS3_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.047599 (rank : 171)
Query Neighborhood Hits	95	Target Neighborhood Hits	89	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

PCSK5_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.133426 (rank : 46)
Query Neighborhood Hits	95	Target Neighborhood Hits	613	Shared Neighborhood Hits	78
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

NOTC2_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.053026 (rank : 151)
Query Neighborhood Hits	95	Target Neighborhood Hits	1113	Shared Neighborhood Hits	48
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.053020 (rank : 152)
Query Neighborhood Hits	95	Target Neighborhood Hits	1069	Shared Neighborhood Hits	46
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

EGFL9_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.062085 (rank : 105)
Query Neighborhood Hits	95	Target Neighborhood Hits	365	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.063179 (rank : 101)
Query Neighborhood Hits	95	Target Neighborhood Hits	379	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

FADD_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.061434 (rank : 107)
Query Neighborhood Hits	95	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

LAMC3_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.112746 (rank : 49)
Query Neighborhood Hits	95	Target Neighborhood Hits	588	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

PGBM_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.068936 (rank : 92)
Query Neighborhood Hits	95	Target Neighborhood Hits	1073	Shared Neighborhood Hits	65
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PLCB4_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.007360 (rank : 189)
Query Neighborhood Hits	95	Target Neighborhood Hits	658	Shared Neighborhood Hits	3
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

SREC2_MOUSE
θ value	3.0926 (rank : 72)	NC score	0.092373 (rank : 64)
Query Neighborhood Hits	95	Target Neighborhood Hits	605	Shared Neighborhood Hits	58
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TNR27_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.257662 (rank : 38)
Query Neighborhood Hits	95	Target Neighborhood Hits	69	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR9_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.445279 (rank : 33)
Query Neighborhood Hits	95	Target Neighborhood Hits	137	Shared Neighborhood Hits	57
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

DLK_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.057098 (rank : 128)
Query Neighborhood Hits	95	Target Neighborhood Hits	374	Shared Neighborhood Hits	42
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

HOME2_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.009202 (rank : 187)
Query Neighborhood Hits	95	Target Neighborhood Hits	532	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

ITCH_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.006318 (rank : 190)
Query Neighborhood Hits	95	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).

PGBM_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.063236 (rank : 100)
Query Neighborhood Hits	95	Target Neighborhood Hits	1113	Shared Neighborhood Hits	60
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SSPO_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.053356 (rank : 149)
Query Neighborhood Hits	95	Target Neighborhood Hits	800	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

THOC1_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.033536 (rank : 175)
Query Neighborhood Hits	95	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R3N6, Q8BWD5, Q8BXY3	Gene names	Thoc1
Domain Architecture
Description	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84).

TNR16_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.539638 (rank : 31)
Query Neighborhood Hits	95	Target Neighborhood Hits	178	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

MEGF8_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.090995 (rank : 66)
Query Neighborhood Hits	95	Target Neighborhood Hits	528	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.083907 (rank : 75)
Query Neighborhood Hits	95	Target Neighborhood Hits	520	Shared Neighborhood Hits	54
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

CUBN_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.048243 (rank : 170)
Query Neighborhood Hits	95	Target Neighborhood Hits	482	Shared Neighborhood Hits	44
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

EMR1_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.035486 (rank : 174)
Query Neighborhood Hits	95	Target Neighborhood Hits	349	Shared Neighborhood Hits	37
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

MATN2_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.054345 (rank : 139)
Query Neighborhood Hits	95	Target Neighborhood Hits	365	Shared Neighborhood Hits	47
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MGR8_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.013710 (rank : 185)
Query Neighborhood Hits	95	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.013736 (rank : 184)
Query Neighborhood Hits	95	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

PERF_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.015141 (rank : 181)
Query Neighborhood Hits	95	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

FBN3_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.059465 (rank : 114)
Query Neighborhood Hits	95	Target Neighborhood Hits	543	Shared Neighborhood Hits	55
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LAMA3_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.090690 (rank : 67)
Query Neighborhood Hits	95	Target Neighborhood Hits	859	Shared Neighborhood Hits	69
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LRP1B_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.039491 (rank : 172)
Query Neighborhood Hits	95	Target Neighborhood Hits	606	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SRCH_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.023778 (rank : 177)
Query Neighborhood Hits	95	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

TOPRS_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.007898 (rank : 188)
Query Neighborhood Hits	95	Target Neighborhood Hits	263	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TSP1_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.035902 (rank : 173)
Query Neighborhood Hits	95	Target Neighborhood Hits	396	Shared Neighborhood Hits	47
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

AGRIN_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.058392 (rank : 120)
Query Neighborhood Hits	95	Target Neighborhood Hits	582	Shared Neighborhood Hits	46
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

COMP_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.054757 (rank : 137)
Query Neighborhood Hits	95	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.065102 (rank : 99)
Query Neighborhood Hits	95	Target Neighborhood Hits	441	Shared Neighborhood Hits	47
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.058951 (rank : 119)
Query Neighborhood Hits	95	Target Neighborhood Hits	524	Shared Neighborhood Hits	45
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.056002 (rank : 130)
Query Neighborhood Hits	95	Target Neighborhood Hits	362	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM1_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.050396 (rank : 168)
Query Neighborhood Hits	95	Target Neighborhood Hits	444	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DLK_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.055431 (rank : 134)
Query Neighborhood Hits	95	Target Neighborhood Hits	401	Shared Neighborhood Hits	44
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.058989 (rank : 118)
Query Neighborhood Hits	95	Target Neighborhood Hits	455	Shared Neighborhood Hits	46
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.059739 (rank : 113)
Query Neighborhood Hits	95	Target Neighborhood Hits	456	Shared Neighborhood Hits	47
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.051679 (rank : 162)
Query Neighborhood Hits	95	Target Neighborhood Hits	419	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.051233 (rank : 164)
Query Neighborhood Hits	95	Target Neighborhood Hits	399	Shared Neighborhood Hits	40
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.062210 (rank : 104)
Query Neighborhood Hits	95	Target Neighborhood Hits	435	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.059164 (rank : 117)
Query Neighborhood Hits	95	Target Neighborhood Hits	440	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.052482 (rank : 157)
Query Neighborhood Hits	95	Target Neighborhood Hits	460	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.053611 (rank : 147)
Query Neighborhood Hits	95	Target Neighborhood Hits	413	Shared Neighborhood Hits	44
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDAR_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.085824 (rank : 73)
Query Neighborhood Hits	95	Target Neighborhood Hits	84	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

EDAR_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.099845 (rank : 55)
Query Neighborhood Hits	95	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

FBLN2_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.052547 (rank : 155)
Query Neighborhood Hits	95	Target Neighborhood Hits	392	Shared Neighborhood Hits	47
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBN1_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.061313 (rank : 110)
Query Neighborhood Hits	95	Target Neighborhood Hits	557	Shared Neighborhood Hits	55
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.061356 (rank : 109)
Query Neighborhood Hits	95	Target Neighborhood Hits	563	Shared Neighborhood Hits	55
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.055068 (rank : 136)
Query Neighborhood Hits	95	Target Neighborhood Hits	560	Shared Neighborhood Hits	52
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.055734 (rank : 133)
Query Neighborhood Hits	95	Target Neighborhood Hits	549	Shared Neighborhood Hits	53
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

JAG1_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.053981 (rank : 141)
Query Neighborhood Hits	95	Target Neighborhood Hits	514	Shared Neighborhood Hits	44
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.052930 (rank : 154)
Query Neighborhood Hits	95	Target Neighborhood Hits	518	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.052053 (rank : 160)
Query Neighborhood Hits	95	Target Neighborhood Hits	491	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.053639 (rank : 146)
Query Neighborhood Hits	95	Target Neighborhood Hits	504	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR104_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.052491 (rank : 156)
Query Neighborhood Hits	95	Target Neighborhood Hits	313	Shared Neighborhood Hits	36
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR510_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.058284 (rank : 121)
Query Neighborhood Hits	95	Target Neighborhood Hits	217	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.051561 (rank : 163)
Query Neighborhood Hits	95	Target Neighborhood Hits	231	Shared Neighborhood Hits	29
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA51_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.070430 (rank : 91)
Query Neighborhood Hits	95	Target Neighborhood Hits	288	Shared Neighborhood Hits	39
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.065552 (rank : 98)
Query Neighborhood Hits	95	Target Neighborhood Hits	236	Shared Neighborhood Hits	36
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.066230 (rank : 97)
Query Neighborhood Hits	95	Target Neighborhood Hits	331	Shared Neighborhood Hits	41
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.067720 (rank : 96)
Query Neighborhood Hits	95	Target Neighborhood Hits	270	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.060954 (rank : 111)
Query Neighborhood Hits	95	Target Neighborhood Hits	257	Shared Neighborhood Hits	36
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.060108 (rank : 112)
Query Neighborhood Hits	95	Target Neighborhood Hits	207	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.050492 (rank : 167)
Query Neighborhood Hits	95	Target Neighborhood Hits	269	Shared Neighborhood Hits	33
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.061576 (rank : 106)
Query Neighborhood Hits	95	Target Neighborhood Hits	324	Shared Neighborhood Hits	37
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.073070 (rank : 88)
Query Neighborhood Hits	95	Target Neighborhood Hits	310	Shared Neighborhood Hits	38
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMA1_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.091373 (rank : 65)
Query Neighborhood Hits	95	Target Neighborhood Hits	838	Shared Neighborhood Hits	66
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.082374 (rank : 76)
Query Neighborhood Hits	95	Target Neighborhood Hits	1092	Shared Neighborhood Hits	64
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.076115 (rank : 86)
Query Neighborhood Hits	95	Target Neighborhood Hits	1198	Shared Neighborhood Hits	59
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.089441 (rank : 70)
Query Neighborhood Hits	95	Target Neighborhood Hits	760	Shared Neighborhood Hits	57
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA4_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.078723 (rank : 82)
Query Neighborhood Hits	95	Target Neighborhood Hits	584	Shared Neighborhood Hits	50
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.076521 (rank : 84)
Query Neighborhood Hits	95	Target Neighborhood Hits	1018	Shared Neighborhood Hits	58
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.080010 (rank : 79)
Query Neighborhood Hits	95	Target Neighborhood Hits	919	Shared Neighborhood Hits	62
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.079946 (rank : 80)
Query Neighborhood Hits	95	Target Neighborhood Hits	692	Shared Neighborhood Hits	55
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.089198 (rank : 71)
Query Neighborhood Hits	95	Target Neighborhood Hits	722	Shared Neighborhood Hits	59
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.067997 (rank : 95)
Query Neighborhood Hits	95	Target Neighborhood Hits	461	Shared Neighborhood Hits	42
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.062931 (rank : 102)
Query Neighborhood Hits	95	Target Neighborhood Hits	444	Shared Neighborhood Hits	42
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.090196 (rank : 68)
Query Neighborhood Hits	95	Target Neighborhood Hits	715	Shared Neighborhood Hits	61
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.114223 (rank : 48)
Query Neighborhood Hits	95	Target Neighborhood Hits	624	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LTB1L_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.053760 (rank : 145)
Query Neighborhood Hits	95	Target Neighborhood Hits	553	Shared Neighborhood Hits	47
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.055878 (rank : 131)
Query Neighborhood Hits	95	Target Neighborhood Hits	514	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.053765 (rank : 144)
Query Neighborhood Hits	95	Target Neighborhood Hits	502	Shared Neighborhood Hits	47
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.055815 (rank : 132)
Query Neighborhood Hits	95	Target Neighborhood Hits	479	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.050763 (rank : 166)
Query Neighborhood Hits	95	Target Neighborhood Hits	552	Shared Neighborhood Hits	49
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.055097 (rank : 135)
Query Neighborhood Hits	95	Target Neighborhood Hits	617	Shared Neighborhood Hits	50
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.050007 (rank : 169)
Query Neighborhood Hits	95	Target Neighborhood Hits	502	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.053355 (rank : 150)
Query Neighborhood Hits	95	Target Neighborhood Hits	607	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MEGF6_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.081145 (rank : 78)
Query Neighborhood Hits	95	Target Neighborhood Hits	671	Shared Neighborhood Hits	64
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF9_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.097418 (rank : 60)
Query Neighborhood Hits	95	Target Neighborhood Hits	557	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.101861 (rank : 54)
Query Neighborhood Hits	95	Target Neighborhood Hits	896	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NELL2_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.057267 (rank : 127)
Query Neighborhood Hits	95	Target Neighborhood Hits	449	Shared Neighborhood Hits	47
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.059280 (rank : 115)
Query Neighborhood Hits	95	Target Neighborhood Hits	436	Shared Neighborhood Hits	47
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NET2_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.053583 (rank : 148)
Query Neighborhood Hits	95	Target Neighborhood Hits	194	Shared Neighborhood Hits	36
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.054570 (rank : 138)
Query Neighborhood Hits	95	Target Neighborhood Hits	193	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET4_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.056810 (rank : 129)
Query Neighborhood Hits	95	Target Neighborhood Hits	191	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.053789 (rank : 143)
Query Neighborhood Hits	95	Target Neighborhood Hits	180	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NOTC3_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.054051 (rank : 140)
Query Neighborhood Hits	95	Target Neighborhood Hits	1062	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.053980 (rank : 142)
Query Neighborhood Hits	95	Target Neighborhood Hits	975	Shared Neighborhood Hits	50
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.052331 (rank : 158)
Query Neighborhood Hits	95	Target Neighborhood Hits	905	Shared Neighborhood Hits	51
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.052985 (rank : 153)
Query Neighborhood Hits	95	Target Neighborhood Hits	872	Shared Neighborhood Hits	50
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NTNG1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.061393 (rank : 108)
Query Neighborhood Hits	95	Target Neighborhood Hits	247	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.062808 (rank : 103)
Query Neighborhood Hits	95	Target Neighborhood Hits	246	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.058048 (rank : 123)
Query Neighborhood Hits	95	Target Neighborhood Hits	276	Shared Neighborhood Hits	37
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.059170 (rank : 116)
Query Neighborhood Hits	95	Target Neighborhood Hits	276	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PCSK6_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.074952 (rank : 87)
Query Neighborhood Hits	95	Target Neighborhood Hits	298	Shared Neighborhood Hits	56
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

SCUB3_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.076177 (rank : 85)
Query Neighborhood Hits	95	Target Neighborhood Hits	428	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.077946 (rank : 83)
Query Neighborhood Hits	95	Target Neighborhood Hits	442	Shared Neighborhood Hits	66
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

STAB2_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.086690 (rank : 72)
Query Neighborhood Hits	95	Target Neighborhood Hits	528	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TNR18_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.224079 (rank : 40)
Query Neighborhood Hits	95	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR18_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.169863 (rank : 42)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR19_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.157510 (rank : 45)
Query Neighborhood Hits	95	Target Neighborhood Hits	89	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR21_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.398860 (rank : 35)
Query Neighborhood Hits	95	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.390331 (rank : 36)
Query Neighborhood Hits	95	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR27_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.219825 (rank : 41)
Query Neighborhood Hits	95	Target Neighborhood Hits	61	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR8_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.374484 (rank : 37)
Query Neighborhood Hits	95	Target Neighborhood Hits	208	Shared Neighborhood Hits	46
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TR19L_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.157748 (rank : 44)
Query Neighborhood Hits	95	Target Neighborhood Hits	99	Shared Neighborhood Hits	32
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TR19L_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.165848 (rank : 43)
Query Neighborhood Hits	95	Target Neighborhood Hits	85	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TRBM_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.052089 (rank : 159)
Query Neighborhood Hits	95	Target Neighborhood Hits	361	Shared Neighborhood Hits	48
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

USH2A_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.072853 (rank : 89)
Query Neighborhood Hits	95	Target Neighborhood Hits	600	Shared Neighborhood Hits	63
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.071579 (rank : 90)
Query Neighborhood Hits	95	Target Neighborhood Hits	626	Shared Neighborhood Hits	59
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

WIF1_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.051766 (rank : 161)
Query Neighborhood Hits	95	Target Neighborhood Hits	392	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.051061 (rank : 165)
Query Neighborhood Hits	95	Target Neighborhood Hits	393	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ZAN_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.082044 (rank : 77)
Query Neighborhood Hits	95	Target Neighborhood Hits	808	Shared Neighborhood Hits	63
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

TNR6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	95
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
NC score	0.934716 (rank : 2)	θ value	2.38869e-85 (rank : 2)
Query Neighborhood Hits	95	Target Neighborhood Hits	99	Shared Neighborhood Hits	57
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR26_MOUSE
NC score	0.757756 (rank : 3)	θ value	6.00763e-12 (rank : 4)
Query Neighborhood Hits	95	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR22_MOUSE
NC score	0.743842 (rank : 4)	θ value	2.28291e-11 (rank : 7)
Query Neighborhood Hits	95	Target Neighborhood Hits	97	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
NC score	0.733317 (rank : 5)	θ value	3.18553e-13 (rank : 3)
Query Neighborhood Hits	95	Target Neighborhood Hits	114	Shared Neighborhood Hits	56
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR14_HUMAN
NC score	0.693876 (rank : 6)	θ value	2.28291e-11 (rank : 6)
Query Neighborhood Hits	95	Target Neighborhood Hits	149	Shared Neighborhood Hits	59
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR7_HUMAN
NC score	0.674071 (rank : 7)	θ value	2.52405e-10 (rank : 13)
Query Neighborhood Hits	95	Target Neighborhood Hits	120	Shared Neighborhood Hits	58
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TR10B_MOUSE
NC score	0.654440 (rank : 8)	θ value	3.29651e-10 (rank : 14)
Query Neighborhood Hits	95	Target Neighborhood Hits	76	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR7_MOUSE
NC score	0.653065 (rank : 9)	θ value	5.08577e-11 (rank : 10)
Query Neighborhood Hits	95	Target Neighborhood Hits	112	Shared Neighborhood Hits	53
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TR10C_HUMAN
NC score	0.649953 (rank : 10)	θ value	7.34386e-10 (rank : 16)
Query Neighborhood Hits	95	Target Neighborhood Hits	105	Shared Neighborhood Hits	38
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR5_MOUSE
NC score	0.646841 (rank : 11)	θ value	2.98157e-11 (rank : 9)
Query Neighborhood Hits	95	Target Neighborhood Hits	131	Shared Neighborhood Hits	53
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR5_HUMAN
NC score	0.646818 (rank : 12)	θ value	9.59137e-10 (rank : 17)
Query Neighborhood Hits	95	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR4_MOUSE
NC score	0.646514 (rank : 13)	θ value	1.17247e-07 (rank : 20)
Query Neighborhood Hits	95	Target Neighborhood Hits	137	Shared Neighborhood Hits	58
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR3_HUMAN
NC score	0.644767 (rank : 14)	θ value	2.28291e-11 (rank : 8)
Query Neighborhood Hits	95	Target Neighborhood Hits	145	Shared Neighborhood Hits	54
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TR10B_HUMAN
NC score	0.633588 (rank : 15)	θ value	1.74796e-11 (rank : 5)
Query Neighborhood Hits	95	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TNR25_HUMAN
NC score	0.625690 (rank : 16)	θ value	1.47974e-10 (rank : 12)
Query Neighborhood Hits	95	Target Neighborhood Hits	172	Shared Neighborhood Hits	56
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR1A_HUMAN
NC score	0.624415 (rank : 17)	θ value	3.19293e-05 (rank : 28)
Query Neighborhood Hits	95	Target Neighborhood Hits	121	Shared Neighborhood Hits	49
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TR11B_HUMAN
NC score	0.623387 (rank : 18)	θ value	4.76016e-09 (rank : 18)
Query Neighborhood Hits	95	Target Neighborhood Hits	92	Shared Neighborhood Hits	52
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR10D_HUMAN
NC score	0.619901 (rank : 19)	θ value	4.30538e-10 (rank : 15)
Query Neighborhood Hits	95	Target Neighborhood Hits	62	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TNR1A_MOUSE
NC score	0.618694 (rank : 20)	θ value	8.40245e-06 (rank : 26)
Query Neighborhood Hits	95	Target Neighborhood Hits	131	Shared Neighborhood Hits	52
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TR11B_MOUSE
NC score	0.617618 (rank : 21)	θ value	1.38499e-08 (rank : 19)
Query Neighborhood Hits	95	Target Neighborhood Hits	95	Shared Neighborhood Hits	50
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR1B_HUMAN
NC score	0.613362 (rank : 22)	θ value	1.99992e-07 (rank : 21)
Query Neighborhood Hits	95	Target Neighborhood Hits	127	Shared Neighborhood Hits	52
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TR10A_HUMAN
NC score	0.611339 (rank : 23)	θ value	8.67504e-11 (rank : 11)
Query Neighborhood Hits	95	Target Neighborhood Hits	82	Shared Neighborhood Hits	42
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TNR6B_HUMAN
NC score	0.603930 (rank : 24)	θ value	9.92553e-07 (rank : 24)
Query Neighborhood Hits	95	Target Neighborhood Hits	103	Shared Neighborhood Hits	49
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR4_HUMAN
NC score	0.603228 (rank : 25)	θ value	7.1131e-05 (rank : 29)
Query Neighborhood Hits	95	Target Neighborhood Hits	152	Shared Neighborhood Hits	54
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR3_MOUSE
NC score	0.597225 (rank : 26)	θ value	1.69304e-06 (rank : 25)
Query Neighborhood Hits	95	Target Neighborhood Hits	113	Shared Neighborhood Hits	51
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR16_HUMAN
NC score	0.571425 (rank : 27)	θ value	2.61198e-07 (rank : 22)
Query Neighborhood Hits	95	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR1B_MOUSE
NC score	0.568095 (rank : 28)	θ value	0.00035302 (rank : 30)
Query Neighborhood Hits	95	Target Neighborhood Hits	123	Shared Neighborhood Hits	47
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR11_HUMAN
NC score	0.558339 (rank : 29)	θ value	5.81887e-07 (rank : 23)
Query Neighborhood Hits	95	Target Neighborhood Hits	135	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
NC score	0.553332 (rank : 30)	θ value	1.09739e-05 (rank : 27)
Query Neighborhood Hits	95	Target Neighborhood Hits	121	Shared Neighborhood Hits	52
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR16_MOUSE
NC score	0.539638 (rank : 31)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	95	Target Neighborhood Hits	178	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR8_HUMAN
NC score	0.480995 (rank : 32)	θ value	0.00509761 (rank : 31)
Query Neighborhood Hits	95	Target Neighborhood Hits	198	Shared Neighborhood Hits	47
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR9_MOUSE
NC score	0.445279 (rank : 33)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	95	Target Neighborhood Hits	137	Shared Neighborhood Hits	57
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR9_HUMAN
NC score	0.438431 (rank : 34)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	95	Target Neighborhood Hits	166	Shared Neighborhood Hits	55
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR21_HUMAN
NC score	0.398860 (rank : 35)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	95	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR21_MOUSE
NC score	0.390331 (rank : 36)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	95	Target Neighborhood Hits	108	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR8_MOUSE
NC score	0.374484 (rank : 37)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	95	Target Neighborhood Hits	208	Shared Neighborhood Hits	46
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR27_HUMAN
NC score	0.257662 (rank : 38)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	95	Target Neighborhood Hits	69	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR19_MOUSE
NC score	0.235285 (rank : 39)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	95	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR18_HUMAN
NC score	0.224079 (rank : 40)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	95	Target Neighborhood Hits	55	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR27_MOUSE
NC score	0.219825 (rank : 41)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	95	Target Neighborhood Hits	61	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR18_MOUSE
NC score	0.169863 (rank : 42)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	95	Target Neighborhood Hits	36	Shared Neighborhood Hits	19
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TR19L_MOUSE
NC score	0.165848 (rank : 43)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	95	Target Neighborhood Hits	85	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TR19L_HUMAN
NC score	0.157748 (rank : 44)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	95	Target Neighborhood Hits	99	Shared Neighborhood Hits	32
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TNR19_HUMAN
NC score	0.157510 (rank : 45)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	95	Target Neighborhood Hits	89	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

PCSK5_MOUSE
NC score	0.133426 (rank : 46)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	95	Target Neighborhood Hits	613	Shared Neighborhood Hits	78
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

LAMA5_HUMAN
NC score	0.118718 (rank : 47)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	95	Target Neighborhood Hits	976	Shared Neighborhood Hits	71
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC3_MOUSE
NC score	0.114223 (rank : 48)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	95	Target Neighborhood Hits	624	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_HUMAN
NC score	0.112746 (rank : 49)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	95	Target Neighborhood Hits	588	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_MOUSE
NC score	0.111422 (rank : 50)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	95	Target Neighborhood Hits	828	Shared Neighborhood Hits	70
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC2_MOUSE
NC score	0.104127 (rank : 51)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	95	Target Neighborhood Hits	614	Shared Neighborhood Hits	69
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

FRAS1_HUMAN
NC score	0.102657 (rank : 52)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	95	Target Neighborhood Hits	759	Shared Neighborhood Hits	68
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PCSK5_HUMAN
NC score	0.101916 (rank : 53)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	95	Target Neighborhood Hits	291	Shared Neighborhood Hits	62
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

MEGF9_MOUSE
NC score	0.101861 (rank : 54)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	95	Target Neighborhood Hits	896	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

EDAR_MOUSE
NC score	0.099845 (rank : 55)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	95	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

LAMC1_HUMAN
NC score	0.099512 (rank : 56)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	95	Target Neighborhood Hits	922	Shared Neighborhood Hits	68
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SREC_HUMAN
NC score	0.098964 (rank : 57)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	95	Target Neighborhood Hits	645	Shared Neighborhood Hits	62
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

FRAS1_MOUSE
NC score	0.098771 (rank : 58)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	95	Target Neighborhood Hits	747	Shared Neighborhood Hits	66
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA1_HUMAN
NC score	0.097735 (rank : 59)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	95	Target Neighborhood Hits	804	Shared Neighborhood Hits	65
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MEGF9_HUMAN
NC score	0.097418 (rank : 60)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	95	Target Neighborhood Hits	557	Shared Neighborhood Hits	58
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

STAB1_HUMAN
NC score	0.096824 (rank : 61)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	95	Target Neighborhood Hits	546	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

SREC2_HUMAN
NC score	0.095836 (rank : 62)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	95	Target Neighborhood Hits	645	Shared Neighborhood Hits	54
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LAMC1_MOUSE
NC score	0.095721 (rank : 63)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	95	Target Neighborhood Hits	856	Shared Neighborhood Hits	66
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SREC2_MOUSE
NC score	0.092373 (rank : 64)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	95	Target Neighborhood Hits	605	Shared Neighborhood Hits	58
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

LAMA1_MOUSE
NC score	0.091373 (rank : 65)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	95	Target Neighborhood Hits	838	Shared Neighborhood Hits	66
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MEGF8_HUMAN
NC score	0.090995 (rank : 66)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	95	Target Neighborhood Hits	528	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMA3_MOUSE
NC score	0.090690 (rank : 67)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	95	Target Neighborhood Hits	859	Shared Neighborhood Hits	69
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMC2_HUMAN
NC score	0.090196 (rank : 68)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	95	Target Neighborhood Hits	715	Shared Neighborhood Hits	61
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

STAB1_MOUSE
NC score	0.089463 (rank : 69)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	95	Target Neighborhood Hits	566	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

LAMA3_HUMAN
NC score	0.089441 (rank : 70)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	95	Target Neighborhood Hits	760	Shared Neighborhood Hits	57
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMB2_MOUSE
NC score	0.089198 (rank : 71)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	95	Target Neighborhood Hits	722	Shared Neighborhood Hits	59
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

STAB2_MOUSE
NC score	0.086690 (rank : 72)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	95	Target Neighborhood Hits	528	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

EDAR_HUMAN
NC score	0.085824 (rank : 73)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	95	Target Neighborhood Hits	84	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

STAB2_HUMAN
NC score	0.085757 (rank : 74)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	95	Target Neighborhood Hits	534	Shared Neighborhood Hits	53
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

MEGF8_MOUSE
NC score	0.083907 (rank : 75)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	95	Target Neighborhood Hits	520	Shared Neighborhood Hits	54
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

LAMA2_HUMAN
NC score	0.082374 (rank : 76)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	95	Target Neighborhood Hits	1092	Shared Neighborhood Hits	64
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ZAN_MOUSE
NC score	0.082044 (rank : 77)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	95	Target Neighborhood Hits	808	Shared Neighborhood Hits	63
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MEGF6_HUMAN
NC score	0.081145 (rank : 78)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	95	Target Neighborhood Hits	671	Shared Neighborhood Hits	64
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LAMB1_MOUSE
NC score	0.080010 (rank : 79)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	95	Target Neighborhood Hits	919	Shared Neighborhood Hits	62
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
NC score	0.079946 (rank : 80)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	95	Target Neighborhood Hits	692	Shared Neighborhood Hits	55
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMA4_HUMAN
NC score	0.079769 (rank : 81)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	95	Target Neighborhood Hits	708	Shared Neighborhood Hits	49
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
NC score	0.078723 (rank : 82)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	95	Target Neighborhood Hits	584	Shared Neighborhood Hits	50
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

SCUB3_MOUSE
NC score	0.077946 (rank : 83)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	95	Target Neighborhood Hits	442	Shared Neighborhood Hits	66
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMB1_HUMAN
NC score	0.076521 (rank : 84)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	95	Target Neighborhood Hits	1018	Shared Neighborhood Hits	58
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SCUB3_HUMAN
NC score	0.076177 (rank : 85)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	95	Target Neighborhood Hits	428	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMA2_MOUSE
NC score	0.076115 (rank : 86)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	95	Target Neighborhood Hits	1198	Shared Neighborhood Hits	59
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

PCSK6_HUMAN
NC score	0.074952 (rank : 87)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	95	Target Neighborhood Hits	298	Shared Neighborhood Hits	56
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

KRA59_HUMAN
NC score	0.073070 (rank : 88)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	95	Target Neighborhood Hits	310	Shared Neighborhood Hits	38
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

USH2A_HUMAN
NC score	0.072853 (rank : 89)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	95	Target Neighborhood Hits	600	Shared Neighborhood Hits	63
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
NC score	0.071579 (rank : 90)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	95	Target Neighborhood Hits	626	Shared Neighborhood Hits	59
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

KRA51_HUMAN
NC score	0.070430 (rank : 91)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	95	Target Neighborhood Hits	288	Shared Neighborhood Hits	39
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

PGBM_MOUSE
NC score	0.068936 (rank : 92)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	95	Target Neighborhood Hits	1073	Shared Neighborhood Hits	65
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MT1M_HUMAN
NC score	0.068487 (rank : 93)	θ value	0.813845 (rank : 51)
Query Neighborhood Hits	95	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

NELL1_HUMAN
NC score	0.068328 (rank : 94)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	95	Target Neighborhood Hits	451	Shared Neighborhood Hits	50
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

LAMB3_HUMAN
NC score	0.067997 (rank : 95)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	95	Target Neighborhood Hits	461	Shared Neighborhood Hits	42
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

KRA54_HUMAN
NC score	0.067720 (rank : 96)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	95	Target Neighborhood Hits	270	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA53_HUMAN
NC score	0.066230 (rank : 97)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	95	Target Neighborhood Hits	331	Shared Neighborhood Hits	41
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA52_HUMAN
NC score	0.065552 (rank : 98)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	95	Target Neighborhood Hits	236	Shared Neighborhood Hits	36
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

CREL1_HUMAN
NC score	0.065102 (rank : 99)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	95	Target Neighborhood Hits	441	Shared Neighborhood Hits	47
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

PGBM_HUMAN
NC score	0.063236 (rank : 100)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	95	Target Neighborhood Hits	1113	Shared Neighborhood Hits	60
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

EGFL9_MOUSE
NC score	0.063179 (rank : 101)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	95	Target Neighborhood Hits	379	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

LAMB3_MOUSE
NC score	0.062931 (rank : 102)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	95	Target Neighborhood Hits	444	Shared Neighborhood Hits	42
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

NTNG1_MOUSE
NC score	0.062808 (rank : 103)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	95	Target Neighborhood Hits	246	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

DLL4_HUMAN
NC score	0.062210 (rank : 104)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	95	Target Neighborhood Hits	435	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EGFL9_HUMAN
NC score	0.062085 (rank : 105)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	95	Target Neighborhood Hits	365	Shared Neighborhood Hits	42
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

KRA58_HUMAN
NC score	0.061576 (rank : 106)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	95	Target Neighborhood Hits	324	Shared Neighborhood Hits	37
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

FADD_MOUSE
NC score	0.061434 (rank : 107)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	95	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q61160, Q3TC37, Q61082	Gene names	Fadd, Mort1
Domain Architecture
Description	FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity).

NTNG1_HUMAN
NC score	0.061393 (rank : 108)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	95	Target Neighborhood Hits	247	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

FBN1_MOUSE
NC score	0.061356 (rank : 109)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	95	Target Neighborhood Hits	563	Shared Neighborhood Hits	55
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_HUMAN
NC score	0.061313 (rank : 110)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	95	Target Neighborhood Hits	557	Shared Neighborhood Hits	55
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

KRA55_HUMAN
NC score	0.060954 (rank : 111)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	95	Target Neighborhood Hits	257	Shared Neighborhood Hits	36
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
NC score	0.060108 (rank : 112)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	95	Target Neighborhood Hits	207	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

DLL1_MOUSE
NC score	0.059739 (rank : 113)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	95	Target Neighborhood Hits	456	Shared Neighborhood Hits	47
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

FBN3_HUMAN
NC score	0.059465 (rank : 114)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	95	Target Neighborhood Hits	543	Shared Neighborhood Hits	55
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

NELL2_MOUSE
NC score	0.059280 (rank : 115)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	95	Target Neighborhood Hits	436	Shared Neighborhood Hits	47
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NTNG2_MOUSE
NC score	0.059170 (rank : 116)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	95	Target Neighborhood Hits	276	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

DLL4_MOUSE
NC score	0.059164 (rank : 117)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	95	Target Neighborhood Hits	440	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL1_HUMAN
NC score	0.058989 (rank : 118)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	95	Target Neighborhood Hits	455	Shared Neighborhood Hits	46
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

CREL1_MOUSE
NC score	0.058951 (rank : 119)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	95	Target Neighborhood Hits	524	Shared Neighborhood Hits	45
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

AGRIN_HUMAN
NC score	0.058392 (rank : 120)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	95	Target Neighborhood Hits	582	Shared Neighborhood Hits	46
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

KR510_HUMAN
NC score	0.058284 (rank : 121)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	95	Target Neighborhood Hits	217	Shared Neighborhood Hits	30
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

NOTC1_MOUSE
NC score	0.058151 (rank : 122)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	95	Target Neighborhood Hits	916	Shared Neighborhood Hits	47
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NTNG2_HUMAN
NC score	0.058048 (rank : 123)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	95	Target Neighborhood Hits	276	Shared Neighborhood Hits	37
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

FBLN1_MOUSE
NC score	0.057997 (rank : 124)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	95	Target Neighborhood Hits	329	Shared Neighborhood Hits	47
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

MATN2_MOUSE
NC score	0.057786 (rank : 125)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	95	Target Neighborhood Hits	356	Shared Neighborhood Hits	47
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

NOTC1_HUMAN
NC score	0.057331 (rank : 126)	θ value	0.813845 (rank : 52)
Query Neighborhood Hits	95	Target Neighborhood Hits	906	Shared Neighborhood Hits	48
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NELL2_HUMAN
NC score	0.057267 (rank : 127)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	95	Target Neighborhood Hits	449	Shared Neighborhood Hits	47
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

DLK_MOUSE
NC score	0.057098 (rank : 128)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	95	Target Neighborhood Hits	374	Shared Neighborhood Hits	42
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

NET4_HUMAN
NC score	0.056810 (rank : 129)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	95	Target Neighborhood Hits	191	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

CRIM1_HUMAN
NC score	0.056002 (rank : 130)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	95	Target Neighborhood Hits	362	Shared Neighborhood Hits	47
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

LTB1L_MOUSE
NC score	0.055878 (rank : 131)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	95	Target Neighborhood Hits	514	Shared Neighborhood Hits	50
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
NC score	0.055815 (rank : 132)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	95	Target Neighborhood Hits	479	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBN2_MOUSE
NC score	0.055734 (rank : 133)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	95	Target Neighborhood Hits	549	Shared Neighborhood Hits	53
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

DLK_HUMAN
NC score	0.055431 (rank : 134)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	95	Target Neighborhood Hits	401	Shared Neighborhood Hits	44
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

LTBP2_MOUSE
NC score	0.055097 (rank : 135)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	95	Target Neighborhood Hits	617	Shared Neighborhood Hits	50
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN2_HUMAN
NC score	0.055068 (rank : 136)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	95	Target Neighborhood Hits	560	Shared Neighborhood Hits	52
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

COMP_MOUSE
NC score	0.054757 (rank : 137)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	95	Target Neighborhood Hits	290	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NET2_MOUSE
NC score	0.054570 (rank : 138)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	95	Target Neighborhood Hits	193	Shared Neighborhood Hits	37
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

MATN2_HUMAN
NC score	0.054345 (rank : 139)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	95	Target Neighborhood Hits	365	Shared Neighborhood Hits	47
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

NOTC3_HUMAN
NC score	0.054051 (rank : 140)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	95	Target Neighborhood Hits	1062	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

JAG1_HUMAN
NC score	0.053981 (rank : 141)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	95	Target Neighborhood Hits	514	Shared Neighborhood Hits	44
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

NOTC3_MOUSE
NC score	0.053980 (rank : 142)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	95	Target Neighborhood Hits	975	Shared Neighborhood Hits	50
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NET4_MOUSE
NC score	0.053789 (rank : 143)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	95	Target Neighborhood Hits	180	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

LTB1S_HUMAN
NC score	0.053765 (rank : 144)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	95	Target Neighborhood Hits	502	Shared Neighborhood Hits	47
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.053760 (rank : 145)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	95	Target Neighborhood Hits	553	Shared Neighborhood Hits	47
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

JAG2_MOUSE
NC score	0.053639 (rank : 146)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	95	Target Neighborhood Hits	504	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

DNER_MOUSE
NC score	0.053611 (rank : 147)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	95	Target Neighborhood Hits	413	Shared Neighborhood Hits	44
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

NET2_HUMAN
NC score	0.053583 (rank : 148)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	95	Target Neighborhood Hits	194	Shared Neighborhood Hits	36
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

SSPO_MOUSE
NC score	0.053356 (rank : 149)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	95	Target Neighborhood Hits	800	Shared Neighborhood Hits	59
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

LTBP4_MOUSE
NC score	0.053355 (rank : 150)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	95	Target Neighborhood Hits	607	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NOTC2_HUMAN
NC score	0.053026 (rank : 151)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	95	Target Neighborhood Hits	1113	Shared Neighborhood Hits	48
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
NC score	0.053020 (rank : 152)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	95	Target Neighborhood Hits	1069	Shared Neighborhood Hits	46
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_MOUSE
NC score	0.052985 (rank : 153)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	95	Target Neighborhood Hits	872	Shared Neighborhood Hits	50
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

JAG1_MOUSE
NC score	0.052930 (rank : 154)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	95	Target Neighborhood Hits	518	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

FBLN2_HUMAN
NC score	0.052547 (rank : 155)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	95	Target Neighborhood Hits	392	Shared Neighborhood Hits	47
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

KR104_HUMAN
NC score	0.052491 (rank : 156)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	95	Target Neighborhood Hits	313	Shared Neighborhood Hits	36
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

DNER_HUMAN
NC score	0.052482 (rank : 157)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	95	Target Neighborhood Hits	460	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

NOTC4_HUMAN
NC score	0.052331 (rank : 158)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	95	Target Neighborhood Hits	905	Shared Neighborhood Hits	51
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

TRBM_MOUSE
NC score	0.052089 (rank : 159)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	95	Target Neighborhood Hits	361	Shared Neighborhood Hits	48
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

JAG2_HUMAN
NC score	0.052053 (rank : 160)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	95	Target Neighborhood Hits	491	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

WIF1_HUMAN
NC score	0.051766 (rank : 161)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	95	Target Neighborhood Hits	392	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

DLL3_HUMAN
NC score	0.051679 (rank : 162)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	95	Target Neighborhood Hits	419	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

KR511_HUMAN
NC score	0.051561 (rank : 163)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	95	Target Neighborhood Hits	231	Shared Neighborhood Hits	29
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

DLL3_MOUSE
NC score	0.051233 (rank : 164)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	95	Target Neighborhood Hits	399	Shared Neighborhood Hits	40
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

WIF1_MOUSE
NC score	0.051061 (rank : 165)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	95	Target Neighborhood Hits	393	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LTBP2_HUMAN
NC score	0.050763 (rank : 166)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	95	Target Neighborhood Hits	552	Shared Neighborhood Hits	49
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KRA57_HUMAN
NC score	0.050492 (rank : 167)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	95	Target Neighborhood Hits	269	Shared Neighborhood Hits	33
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

CRUM1_MOUSE
NC score	0.050396 (rank : 168)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	95	Target Neighborhood Hits	444	Shared Neighborhood Hits	41
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

LTBP3_HUMAN
NC score	0.050007 (rank : 169)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	95	Target Neighborhood Hits	502	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

CUBN_HUMAN
NC score	0.048243 (rank : 170)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	95	Target Neighborhood Hits	482	Shared Neighborhood Hits	44
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

MKS3_MOUSE
NC score	0.047599 (rank : 171)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	95	Target Neighborhood Hits	89	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

LRP1B_MOUSE
NC score	0.039491 (rank : 172)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	95	Target Neighborhood Hits	606	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TSP1_MOUSE
NC score	0.035902 (rank : 173)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	95	Target Neighborhood Hits	396	Shared Neighborhood Hits	47
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

EMR1_MOUSE
NC score	0.035486 (rank : 174)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	95	Target Neighborhood Hits	349	Shared Neighborhood Hits	37
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

THOC1_MOUSE
NC score	0.033536 (rank : 175)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	95	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R3N6, Q8BWD5, Q8BXY3	Gene names	Thoc1
Domain Architecture
Description	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84).

V2RX_MOUSE
NC score	0.026888 (rank : 176)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	95	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

SRCH_HUMAN
NC score	0.023778 (rank : 177)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	95	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	P23327, Q504Y6	Gene names	HRC, HCP
Domain Architecture	No domain graphic available
Description	Sarcoplasmic reticulum histidine-rich calcium-binding protein precursor.

EMR4_MOUSE
NC score	0.020687 (rank : 178)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	95	Target Neighborhood Hits	191	Shared Neighborhood Hits	13
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

ABLM2_MOUSE
NC score	0.017662 (rank : 179)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	95	Target Neighborhood Hits	306	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BL65, Q6H8P8, Q80WK6, Q8BUT1, Q8BXI7	Gene names	Ablim2
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

ABLM2_HUMAN
NC score	0.016678 (rank : 180)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	95	Target Neighborhood Hits	317	Shared Neighborhood Hits	5
SwissProt Accessions	Q6H8Q1, Q6H8Q0, Q6NX73, Q8N3C5, Q8N9E9, Q8N9G2, Q96JL7	Gene names	ABLIM2, KIAA1808
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 2 (Actin-binding LIM protein family member 2) (abLIM-2).

PERF_HUMAN
NC score	0.015141 (rank : 181)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	95	Target Neighborhood Hits	48	Shared Neighborhood Hits	4
SwissProt Accessions	P14222, Q86WX7	Gene names	PRF1, PFP
Domain Architecture
Description	Perforin-1 precursor (P1) (Lymphocyte pore-forming protein) (PFP) (Cytolysin).

RIPK1_MOUSE
NC score	0.014513 (rank : 182)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	95	Target Neighborhood Hits	874	Shared Neighborhood Hits	10
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

COGA1_HUMAN
NC score	0.014271 (rank : 183)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	95	Target Neighborhood Hits	345	Shared Neighborhood Hits	10
SwissProt Accessions	Q07092	Gene names	COL16A1
Domain Architecture
Description	Collagen alpha-1(XVI) chain precursor.

MGR8_MOUSE
NC score	0.013736 (rank : 184)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	95	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_HUMAN
NC score	0.013710 (rank : 185)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	95	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

RIPK1_HUMAN
NC score	0.010923 (rank : 186)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	95	Target Neighborhood Hits	891	Shared Neighborhood Hits	12
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

HOME2_HUMAN
NC score	0.009202 (rank : 187)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	95	Target Neighborhood Hits	532	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NSB8, O95269, O95349, Q9NSB6, Q9NSB7, Q9UNT7	Gene names	HOMER2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin).

TOPRS_MOUSE
NC score	0.007898 (rank : 188)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	95	Target Neighborhood Hits	263	Shared Neighborhood Hits	2
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

PLCB4_HUMAN
NC score	0.007360 (rank : 189)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	95	Target Neighborhood Hits	658	Shared Neighborhood Hits	3
SwissProt Accessions	Q15147, Q5JYS8, Q5JYT0, Q5JYT4, Q9BQW5, Q9BQW6, Q9BQW8, Q9UJQ2	Gene names	PLCB4
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-4) (PLC-beta-4).

ITCH_HUMAN
NC score	0.006318 (rank : 190)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	95	Target Neighborhood Hits	162	Shared Neighborhood Hits	3
SwissProt Accessions	Q96J02, O43584, Q5TEL0, Q96F66, Q9BY75, Q9H451, Q9H4U5	Gene names	ITCH
Domain Architecture
Description	Itchy homolog E3 ubiquitin protein ligase (EC 6.3.2.-) (Itch) (Atrophin-1-interacting protein 4) (AIP4) (NFE2-associated polypeptide 1) (NAPP1).