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Network neighborhood for query Sequence : TNR16_HUMAN

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TNR16_HUMAN
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TNR16_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	183	Target Neighborhood Hits	183	Shared Neighborhood Hits	183
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	0 (rank : 2)	NC score	0.972067 (rank : 2)
Query Neighborhood Hits	183	Target Neighborhood Hits	178	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR5_MOUSE
θ value	1.29331e-14 (rank : 3)	NC score	0.715712 (rank : 7)
Query Neighborhood Hits	183	Target Neighborhood Hits	131	Shared Neighborhood Hits	75
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TR11B_MOUSE
θ value	6.41864e-14 (rank : 4)	NC score	0.686589 (rank : 9)
Query Neighborhood Hits	183	Target Neighborhood Hits	95	Shared Neighborhood Hits	66
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TR11B_HUMAN
θ value	1.2105e-12 (rank : 5)	NC score	0.685053 (rank : 12)
Query Neighborhood Hits	183	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR14_HUMAN
θ value	1.58096e-12 (rank : 6)	NC score	0.746085 (rank : 3)
Query Neighborhood Hits	183	Target Neighborhood Hits	149	Shared Neighborhood Hits	91
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR26_MOUSE
θ value	1.58096e-12 (rank : 7)	NC score	0.739504 (rank : 4)
Query Neighborhood Hits	183	Target Neighborhood Hits	106	Shared Neighborhood Hits	67
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR23_MOUSE
θ value	3.52202e-12 (rank : 8)	NC score	0.738600 (rank : 5)
Query Neighborhood Hits	183	Target Neighborhood Hits	114	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR4_HUMAN
θ value	3.52202e-12 (rank : 9)	NC score	0.706537 (rank : 8)
Query Neighborhood Hits	183	Target Neighborhood Hits	152	Shared Neighborhood Hits	86
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TNR22_MOUSE
θ value	4.59992e-12 (rank : 10)	NC score	0.734872 (rank : 6)
Query Neighborhood Hits	183	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR1B_HUMAN
θ value	7.84624e-12 (rank : 11)	NC score	0.678477 (rank : 13)
Query Neighborhood Hits	183	Target Neighborhood Hits	127	Shared Neighborhood Hits	70
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR5_HUMAN
θ value	7.84624e-12 (rank : 12)	NC score	0.686013 (rank : 11)
Query Neighborhood Hits	183	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR1A_HUMAN
θ value	1.33837e-11 (rank : 13)	NC score	0.614230 (rank : 21)
Query Neighborhood Hits	183	Target Neighborhood Hits	121	Shared Neighborhood Hits	66
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR1B_MOUSE
θ value	2.52405e-10 (rank : 14)	NC score	0.652156 (rank : 15)
Query Neighborhood Hits	183	Target Neighborhood Hits	123	Shared Neighborhood Hits	60
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR21_MOUSE
θ value	2.52405e-10 (rank : 15)	NC score	0.598609 (rank : 24)
Query Neighborhood Hits	183	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TR10C_HUMAN
θ value	4.30538e-10 (rank : 16)	NC score	0.592624 (rank : 25)
Query Neighborhood Hits	183	Target Neighborhood Hits	105	Shared Neighborhood Hits	53
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR21_HUMAN
θ value	7.34386e-10 (rank : 17)	NC score	0.603348 (rank : 22)
Query Neighborhood Hits	183	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR11_HUMAN
θ value	9.59137e-10 (rank : 18)	NC score	0.634182 (rank : 17)
Query Neighborhood Hits	183	Target Neighborhood Hits	135	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	3.64472e-09 (rank : 19)	NC score	0.625284 (rank : 18)
Query Neighborhood Hits	183	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR6B_HUMAN
θ value	4.76016e-09 (rank : 20)	NC score	0.670736 (rank : 14)
Query Neighborhood Hits	183	Target Neighborhood Hits	103	Shared Neighborhood Hits	70
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR4_MOUSE
θ value	1.80886e-08 (rank : 21)	NC score	0.686105 (rank : 10)
Query Neighborhood Hits	183	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR6_HUMAN
θ value	2.61198e-07 (rank : 22)	NC score	0.571425 (rank : 27)
Query Neighborhood Hits	183	Target Neighborhood Hits	95	Shared Neighborhood Hits	60
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	2.61198e-07 (rank : 23)	NC score	0.623934 (rank : 19)
Query Neighborhood Hits	183	Target Neighborhood Hits	99	Shared Neighborhood Hits	64
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR3_HUMAN
θ value	5.81887e-07 (rank : 24)	NC score	0.640604 (rank : 16)
Query Neighborhood Hits	183	Target Neighborhood Hits	145	Shared Neighborhood Hits	78
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TR10D_HUMAN
θ value	5.81887e-07 (rank : 25)	NC score	0.514564 (rank : 35)
Query Neighborhood Hits	183	Target Neighborhood Hits	62	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TNR7_HUMAN
θ value	1.29631e-06 (rank : 26)	NC score	0.579691 (rank : 26)
Query Neighborhood Hits	183	Target Neighborhood Hits	120	Shared Neighborhood Hits	71
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

LAMC3_HUMAN
θ value	2.88788e-06 (rank : 27)	NC score	0.308179 (rank : 39)
Query Neighborhood Hits	183	Target Neighborhood Hits	588	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA4_HUMAN
θ value	4.92598e-06 (rank : 28)	NC score	0.262208 (rank : 57)
Query Neighborhood Hits	183	Target Neighborhood Hits	708	Shared Neighborhood Hits	77
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TR10B_HUMAN
θ value	6.43352e-06 (rank : 29)	NC score	0.516810 (rank : 33)
Query Neighborhood Hits	183	Target Neighborhood Hits	71	Shared Neighborhood Hits	56
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TNR7_MOUSE
θ value	1.09739e-05 (rank : 30)	NC score	0.544722 (rank : 29)
Query Neighborhood Hits	183	Target Neighborhood Hits	112	Shared Neighborhood Hits	62
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

LAMA4_MOUSE
θ value	1.87187e-05 (rank : 31)	NC score	0.277259 (rank : 49)
Query Neighborhood Hits	183	Target Neighborhood Hits	584	Shared Neighborhood Hits	79
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

TR10B_MOUSE
θ value	1.87187e-05 (rank : 32)	NC score	0.516499 (rank : 34)
Query Neighborhood Hits	183	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TNR3_MOUSE
θ value	2.44474e-05 (rank : 33)	NC score	0.615728 (rank : 20)
Query Neighborhood Hits	183	Target Neighborhood Hits	113	Shared Neighborhood Hits	79
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

LAMA5_HUMAN
θ value	4.1701e-05 (rank : 34)	NC score	0.302688 (rank : 42)
Query Neighborhood Hits	183	Target Neighborhood Hits	976	Shared Neighborhood Hits	140
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

TR10A_HUMAN
θ value	4.1701e-05 (rank : 35)	NC score	0.495244 (rank : 36)
Query Neighborhood Hits	183	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

LAMA1_MOUSE
θ value	9.29e-05 (rank : 36)	NC score	0.290102 (rank : 46)
Query Neighborhood Hits	183	Target Neighborhood Hits	838	Shared Neighborhood Hits	127
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA5_MOUSE
θ value	9.29e-05 (rank : 37)	NC score	0.305281 (rank : 41)
Query Neighborhood Hits	183	Target Neighborhood Hits	828	Shared Neighborhood Hits	138
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC3_MOUSE
θ value	0.000158464 (rank : 38)	NC score	0.307750 (rank : 40)
Query Neighborhood Hits	183	Target Neighborhood Hits	624	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

TNR9_HUMAN
θ value	0.000158464 (rank : 39)	NC score	0.544469 (rank : 30)
Query Neighborhood Hits	183	Target Neighborhood Hits	166	Shared Neighborhood Hits	86
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

FRAS1_HUMAN
θ value	0.00020696 (rank : 40)	NC score	0.225326 (rank : 71)
Query Neighborhood Hits	183	Target Neighborhood Hits	759	Shared Neighborhood Hits	136
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PCSK5_MOUSE
θ value	0.00020696 (rank : 41)	NC score	0.262865 (rank : 56)
Query Neighborhood Hits	183	Target Neighborhood Hits	613	Shared Neighborhood Hits	142
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TNR1A_MOUSE
θ value	0.00020696 (rank : 42)	NC score	0.600368 (rank : 23)
Query Neighborhood Hits	183	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR9_MOUSE
θ value	0.000270298 (rank : 43)	NC score	0.566833 (rank : 28)
Query Neighborhood Hits	183	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

LAMC1_MOUSE
θ value	0.000461057 (rank : 44)	NC score	0.275200 (rank : 51)
Query Neighborhood Hits	183	Target Neighborhood Hits	856	Shared Neighborhood Hits	124
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TNR8_HUMAN
θ value	0.000461057 (rank : 45)	NC score	0.527873 (rank : 32)
Query Neighborhood Hits	183	Target Neighborhood Hits	198	Shared Neighborhood Hits	82
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

LAMA1_HUMAN
θ value	0.000602161 (rank : 46)	NC score	0.294375 (rank : 44)
Query Neighborhood Hits	183	Target Neighborhood Hits	804	Shared Neighborhood Hits	124
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC1_HUMAN
θ value	0.000602161 (rank : 47)	NC score	0.273213 (rank : 52)
Query Neighborhood Hits	183	Target Neighborhood Hits	922	Shared Neighborhood Hits	122
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

FRAS1_MOUSE
θ value	0.000786445 (rank : 48)	NC score	0.214191 (rank : 78)
Query Neighborhood Hits	183	Target Neighborhood Hits	747	Shared Neighborhood Hits	127
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMA2_MOUSE
θ value	0.00102713 (rank : 49)	NC score	0.251677 (rank : 60)
Query Neighborhood Hits	183	Target Neighborhood Hits	1198	Shared Neighborhood Hits	115
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

FBN2_MOUSE
θ value	0.00134147 (rank : 50)	NC score	0.168021 (rank : 114)
Query Neighborhood Hits	183	Target Neighborhood Hits	549	Shared Neighborhood Hits	109
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

KRA54_HUMAN
θ value	0.00228821 (rank : 51)	NC score	0.242657 (rank : 63)
Query Neighborhood Hits	183	Target Neighborhood Hits	270	Shared Neighborhood Hits	64
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

TNR19_MOUSE
θ value	0.00228821 (rank : 52)	NC score	0.322903 (rank : 38)
Query Neighborhood Hits	183	Target Neighborhood Hits	100	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR8_MOUSE
θ value	0.00228821 (rank : 53)	NC score	0.454796 (rank : 37)
Query Neighborhood Hits	183	Target Neighborhood Hits	208	Shared Neighborhood Hits	70
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

PGBM_MOUSE
θ value	0.00509761 (rank : 54)	NC score	0.188827 (rank : 99)
Query Neighborhood Hits	183	Target Neighborhood Hits	1073	Shared Neighborhood Hits	122
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LAMA2_HUMAN
θ value	0.00665767 (rank : 55)	NC score	0.266237 (rank : 54)
Query Neighborhood Hits	183	Target Neighborhood Hits	1092	Shared Neighborhood Hits	123
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

FBN2_HUMAN
θ value	0.00869519 (rank : 56)	NC score	0.165006 (rank : 119)
Query Neighborhood Hits	183	Target Neighborhood Hits	560	Shared Neighborhood Hits	111
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBLN2_HUMAN
θ value	0.0148317 (rank : 57)	NC score	0.142562 (rank : 142)
Query Neighborhood Hits	183	Target Neighborhood Hits	392	Shared Neighborhood Hits	85
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LAMB1_MOUSE
θ value	0.0148317 (rank : 58)	NC score	0.244528 (rank : 62)
Query Neighborhood Hits	183	Target Neighborhood Hits	919	Shared Neighborhood Hits	119
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMC2_MOUSE
θ value	0.0148317 (rank : 59)	NC score	0.295532 (rank : 43)
Query Neighborhood Hits	183	Target Neighborhood Hits	614	Shared Neighborhood Hits	130
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

PGBM_HUMAN
θ value	0.0148317 (rank : 60)	NC score	0.176474 (rank : 104)
Query Neighborhood Hits	183	Target Neighborhood Hits	1113	Shared Neighborhood Hits	114
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KRA58_HUMAN
θ value	0.0193708 (rank : 61)	NC score	0.204950 (rank : 85)
Query Neighborhood Hits	183	Target Neighborhood Hits	324	Shared Neighborhood Hits	77
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMB1_HUMAN
θ value	0.0193708 (rank : 62)	NC score	0.235496 (rank : 65)
Query Neighborhood Hits	183	Target Neighborhood Hits	1018	Shared Neighborhood Hits	114
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SREC_HUMAN
θ value	0.0193708 (rank : 63)	NC score	0.235342 (rank : 66)
Query Neighborhood Hits	183	Target Neighborhood Hits	645	Shared Neighborhood Hits	125
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LAMC2_HUMAN
θ value	0.0252991 (rank : 64)	NC score	0.275905 (rank : 50)
Query Neighborhood Hits	183	Target Neighborhood Hits	715	Shared Neighborhood Hits	119
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LTBP2_MOUSE
θ value	0.0330416 (rank : 65)	NC score	0.149878 (rank : 129)
Query Neighborhood Hits	183	Target Neighborhood Hits	617	Shared Neighborhood Hits	112
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

STAB2_MOUSE
θ value	0.0330416 (rank : 66)	NC score	0.184293 (rank : 101)
Query Neighborhood Hits	183	Target Neighborhood Hits	528	Shared Neighborhood Hits	118
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

PCSK6_HUMAN
θ value	0.0431538 (rank : 67)	NC score	0.165426 (rank : 118)
Query Neighborhood Hits	183	Target Neighborhood Hits	298	Shared Neighborhood Hits	87
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

TNR25_HUMAN
θ value	0.0431538 (rank : 68)	NC score	0.528311 (rank : 31)
Query Neighborhood Hits	183	Target Neighborhood Hits	172	Shared Neighborhood Hits	88
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

FBN1_HUMAN
θ value	0.0563607 (rank : 69)	NC score	0.168375 (rank : 113)
Query Neighborhood Hits	183	Target Neighborhood Hits	557	Shared Neighborhood Hits	115
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

LAMA3_HUMAN
θ value	0.0563607 (rank : 70)	NC score	0.260795 (rank : 58)
Query Neighborhood Hits	183	Target Neighborhood Hits	760	Shared Neighborhood Hits	99
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MEGF9_HUMAN
θ value	0.0563607 (rank : 71)	NC score	0.281823 (rank : 47)
Query Neighborhood Hits	183	Target Neighborhood Hits	557	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

WIF1_HUMAN
θ value	0.0563607 (rank : 72)	NC score	0.157353 (rank : 122)
Query Neighborhood Hits	183	Target Neighborhood Hits	392	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

EPHB6_MOUSE
θ value	0.0736092 (rank : 73)	NC score	0.032766 (rank : 391)
Query Neighborhood Hits	183	Target Neighborhood Hits	906	Shared Neighborhood Hits	54
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FBN1_MOUSE
θ value	0.0736092 (rank : 74)	NC score	0.167991 (rank : 115)
Query Neighborhood Hits	183	Target Neighborhood Hits	563	Shared Neighborhood Hits	113
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

TRBM_MOUSE
θ value	0.0736092 (rank : 75)	NC score	0.142009 (rank : 144)
Query Neighborhood Hits	183	Target Neighborhood Hits	361	Shared Neighborhood Hits	89
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

ANK3_HUMAN
θ value	0.0961366 (rank : 76)	NC score	0.022766 (rank : 397)
Query Neighborhood Hits	183	Target Neighborhood Hits	853	Shared Neighborhood Hits	22
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

MLL2_HUMAN
θ value	0.0961366 (rank : 77)	NC score	0.049017 (rank : 383)
Query Neighborhood Hits	183	Target Neighborhood Hits	1788	Shared Neighborhood Hits	40
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

USH2A_HUMAN
θ value	0.0961366 (rank : 78)	NC score	0.225725 (rank : 70)
Query Neighborhood Hits	183	Target Neighborhood Hits	600	Shared Neighborhood Hits	118
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

THOC1_MOUSE
θ value	0.125558 (rank : 79)	NC score	0.066671 (rank : 328)
Query Neighborhood Hits	183	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3N6, Q8BWD5, Q8BXY3	Gene names	Thoc1
Domain Architecture
Description	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84).

USH2A_MOUSE
θ value	0.125558 (rank : 80)	NC score	0.233163 (rank : 67)
Query Neighborhood Hits	183	Target Neighborhood Hits	626	Shared Neighborhood Hits	117
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

FBLN5_HUMAN
θ value	0.163984 (rank : 81)	NC score	0.127185 (rank : 175)
Query Neighborhood Hits	183	Target Neighborhood Hits	329	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

KRA24_HUMAN
θ value	0.163984 (rank : 82)	NC score	0.104503 (rank : 206)
Query Neighborhood Hits	183	Target Neighborhood Hits	192	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

SLIT3_HUMAN
θ value	0.163984 (rank : 83)	NC score	0.096343 (rank : 236)
Query Neighborhood Hits	183	Target Neighborhood Hits	682	Shared Neighborhood Hits	85
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

TNR19_HUMAN
θ value	0.163984 (rank : 84)	NC score	0.254099 (rank : 59)
Query Neighborhood Hits	183	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

FBN3_HUMAN
θ value	0.279714 (rank : 85)	NC score	0.165848 (rank : 117)
Query Neighborhood Hits	183	Target Neighborhood Hits	543	Shared Neighborhood Hits	112
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

MEGF6_HUMAN
θ value	0.279714 (rank : 86)	NC score	0.212832 (rank : 79)
Query Neighborhood Hits	183	Target Neighborhood Hits	671	Shared Neighborhood Hits	127
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

WIF1_MOUSE
θ value	0.279714 (rank : 87)	NC score	0.161086 (rank : 121)
Query Neighborhood Hits	183	Target Neighborhood Hits	393	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

KRA52_HUMAN
θ value	0.365318 (rank : 88)	NC score	0.207987 (rank : 82)
Query Neighborhood Hits	183	Target Neighborhood Hits	236	Shared Neighborhood Hits	60
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LAMA3_MOUSE
θ value	0.365318 (rank : 89)	NC score	0.266602 (rank : 53)
Query Neighborhood Hits	183	Target Neighborhood Hits	859	Shared Neighborhood Hits	124
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

SCUB3_MOUSE
θ value	0.365318 (rank : 90)	NC score	0.179104 (rank : 103)
Query Neighborhood Hits	183	Target Neighborhood Hits	442	Shared Neighborhood Hits	132
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LTBP4_MOUSE
θ value	0.47712 (rank : 91)	NC score	0.150593 (rank : 126)
Query Neighborhood Hits	183	Target Neighborhood Hits	607	Shared Neighborhood Hits	105
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MEGF9_MOUSE
θ value	0.47712 (rank : 92)	NC score	0.277905 (rank : 48)
Query Neighborhood Hits	183	Target Neighborhood Hits	896	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SLIT1_MOUSE
θ value	0.47712 (rank : 93)	NC score	0.104375 (rank : 208)
Query Neighborhood Hits	183	Target Neighborhood Hits	715	Shared Neighborhood Hits	91
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SSPO_MOUSE
θ value	0.47712 (rank : 94)	NC score	0.118966 (rank : 184)
Query Neighborhood Hits	183	Target Neighborhood Hits	800	Shared Neighborhood Hits	124
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

THYG_MOUSE
θ value	0.47712 (rank : 95)	NC score	0.051787 (rank : 378)
Query Neighborhood Hits	183	Target Neighborhood Hits	161	Shared Neighborhood Hits	50
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

EDAR_HUMAN
θ value	0.62314 (rank : 96)	NC score	0.162289 (rank : 120)
Query Neighborhood Hits	183	Target Neighborhood Hits	84	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

EDAR_MOUSE
θ value	0.62314 (rank : 97)	NC score	0.154427 (rank : 124)
Query Neighborhood Hits	183	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

KRA53_HUMAN
θ value	0.62314 (rank : 98)	NC score	0.208394 (rank : 81)
Query Neighborhood Hits	183	Target Neighborhood Hits	331	Shared Neighborhood Hits	83
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

SREC2_HUMAN
θ value	0.62314 (rank : 99)	NC score	0.226038 (rank : 69)
Query Neighborhood Hits	183	Target Neighborhood Hits	645	Shared Neighborhood Hits	112
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ZFP13_MOUSE
θ value	0.62314 (rank : 100)	NC score	-0.003685 (rank : 427)
Query Neighborhood Hits	183	Target Neighborhood Hits	771	Shared Neighborhood Hits	6
SwissProt Accessions	P10754, Q80WS0, Q8CDD0	Gene names	Zfp13, Krox-8, Zfp-13
Domain Architecture	No domain graphic available
Description	Zinc finger protein 13 (Zfp-13) (Krox-8 protein).

EPHA6_MOUSE
θ value	0.813845 (rank : 101)	NC score	0.026947 (rank : 396)
Query Neighborhood Hits	183	Target Neighborhood Hits	946	Shared Neighborhood Hits	44
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

FBLN5_MOUSE
θ value	0.813845 (rank : 102)	NC score	0.121000 (rank : 182)
Query Neighborhood Hits	183	Target Neighborhood Hits	317	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FURIN_HUMAN
θ value	0.813845 (rank : 103)	NC score	0.061595 (rank : 344)
Query Neighborhood Hits	183	Target Neighborhood Hits	52	Shared Neighborhood Hits	11
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

MATN2_MOUSE
θ value	0.813845 (rank : 104)	NC score	0.124097 (rank : 180)
Query Neighborhood Hits	183	Target Neighborhood Hits	356	Shared Neighborhood Hits	77
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MLL3_HUMAN
θ value	0.813845 (rank : 105)	NC score	0.047574 (rank : 385)
Query Neighborhood Hits	183	Target Neighborhood Hits	1644	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RIPK1_MOUSE
θ value	0.813845 (rank : 106)	NC score	0.010923 (rank : 414)
Query Neighborhood Hits	183	Target Neighborhood Hits	874	Shared Neighborhood Hits	23
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

ADA23_MOUSE
θ value	1.06291 (rank : 107)	NC score	0.040525 (rank : 390)
Query Neighborhood Hits	183	Target Neighborhood Hits	245	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

DNER_MOUSE
θ value	1.06291 (rank : 108)	NC score	0.151579 (rank : 125)
Query Neighborhood Hits	183	Target Neighborhood Hits	413	Shared Neighborhood Hits	86
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

KRA59_HUMAN
θ value	1.06291 (rank : 109)	NC score	0.223427 (rank : 72)
Query Neighborhood Hits	183	Target Neighborhood Hits	310	Shared Neighborhood Hits	80
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

MLL3_MOUSE
θ value	1.06291 (rank : 110)	NC score	0.050149 (rank : 382)
Query Neighborhood Hits	183	Target Neighborhood Hits	1399	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ADA23_HUMAN
θ value	1.38821 (rank : 111)	NC score	0.041484 (rank : 389)
Query Neighborhood Hits	183	Target Neighborhood Hits	235	Shared Neighborhood Hits	57
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

EPHB6_HUMAN
θ value	1.38821 (rank : 112)	NC score	0.032027 (rank : 392)
Query Neighborhood Hits	183	Target Neighborhood Hits	912	Shared Neighborhood Hits	59
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

RIPK1_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.010904 (rank : 415)
Query Neighborhood Hits	183	Target Neighborhood Hits	891	Shared Neighborhood Hits	25
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

SLIT1_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.098487 (rank : 227)
Query Neighborhood Hits	183	Target Neighborhood Hits	700	Shared Neighborhood Hits	87
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

THOC1_HUMAN
θ value	1.38821 (rank : 115)	NC score	0.054738 (rank : 368)
Query Neighborhood Hits	183	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q96FV9, Q15219	Gene names	THOC1, HPR1
Domain Architecture
Description	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84).

TRI56_MOUSE
θ value	1.38821 (rank : 116)	NC score	0.029107 (rank : 393)
Query Neighborhood Hits	183	Target Neighborhood Hits	255	Shared Neighborhood Hits	12
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

C1QR1_MOUSE
θ value	1.81305 (rank : 117)	NC score	0.111615 (rank : 191)
Query Neighborhood Hits	183	Target Neighborhood Hits	342	Shared Neighborhood Hits	80
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

DAPK1_HUMAN
θ value	1.81305 (rank : 118)	NC score	0.002485 (rank : 425)
Query Neighborhood Hits	183	Target Neighborhood Hits	1130	Shared Neighborhood Hits	19
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

KRA51_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.223375 (rank : 73)
Query Neighborhood Hits	183	Target Neighborhood Hits	288	Shared Neighborhood Hits	77
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LAMB2_MOUSE
θ value	1.81305 (rank : 120)	NC score	0.251441 (rank : 61)
Query Neighborhood Hits	183	Target Neighborhood Hits	722	Shared Neighborhood Hits	118
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.219845 (rank : 75)
Query Neighborhood Hits	183	Target Neighborhood Hits	461	Shared Neighborhood Hits	81
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LDLR_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.093474 (rank : 247)
Query Neighborhood Hits	183	Target Neighborhood Hits	375	Shared Neighborhood Hits	80
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

MATN2_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.124684 (rank : 179)
Query Neighborhood Hits	183	Target Neighborhood Hits	365	Shared Neighborhood Hits	77
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

PCSK5_HUMAN
θ value	1.81305 (rank : 124)	NC score	0.174465 (rank : 107)
Query Neighborhood Hits	183	Target Neighborhood Hits	291	Shared Neighborhood Hits	101
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

SREC2_MOUSE
θ value	1.81305 (rank : 125)	NC score	0.219882 (rank : 74)
Query Neighborhood Hits	183	Target Neighborhood Hits	605	Shared Neighborhood Hits	116
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CELR1_MOUSE
θ value	2.36792 (rank : 126)	NC score	0.074139 (rank : 308)
Query Neighborhood Hits	183	Target Neighborhood Hits	617	Shared Neighborhood Hits	87
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

EPHA6_HUMAN
θ value	2.36792 (rank : 127)	NC score	0.027013 (rank : 395)
Query Neighborhood Hits	183	Target Neighborhood Hits	959	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA7_HUMAN
θ value	2.36792 (rank : 128)	NC score	0.028582 (rank : 394)
Query Neighborhood Hits	183	Target Neighborhood Hits	1053	Shared Neighborhood Hits	68
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

MUC13_MOUSE
θ value	2.36792 (rank : 129)	NC score	0.078182 (rank : 290)
Query Neighborhood Hits	183	Target Neighborhood Hits	447	Shared Neighborhood Hits	58
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SORL_MOUSE
θ value	2.36792 (rank : 130)	NC score	0.078077 (rank : 291)
Query Neighborhood Hits	183	Target Neighborhood Hits	439	Shared Neighborhood Hits	81
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

VWF_HUMAN
θ value	2.36792 (rank : 131)	NC score	0.101159 (rank : 221)
Query Neighborhood Hits	183	Target Neighborhood Hits	396	Shared Neighborhood Hits	90
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

AGRIN_HUMAN
θ value	3.0926 (rank : 132)	NC score	0.196959 (rank : 93)
Query Neighborhood Hits	183	Target Neighborhood Hits	582	Shared Neighborhood Hits	97
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CNBP_HUMAN
θ value	3.0926 (rank : 133)	NC score	0.063249 (rank : 335)
Query Neighborhood Hits	183	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	P62633, P20694, Q5QJR0, Q6PJI7, Q96NV3	Gene names	CNBP, ZNF9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

FBLN2_MOUSE
θ value	3.0926 (rank : 134)	NC score	0.128127 (rank : 171)
Query Neighborhood Hits	183	Target Neighborhood Hits	505	Shared Neighborhood Hits	88
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

ROBO3_HUMAN
θ value	3.0926 (rank : 135)	NC score	0.014290 (rank : 408)
Query Neighborhood Hits	183	Target Neighborhood Hits	570	Shared Neighborhood Hits	19
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

SCUB3_HUMAN
θ value	3.0926 (rank : 136)	NC score	0.171151 (rank : 108)
Query Neighborhood Hits	183	Target Neighborhood Hits	428	Shared Neighborhood Hits	128
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

TIF1A_HUMAN
θ value	3.0926 (rank : 137)	NC score	0.014213 (rank : 409)
Query Neighborhood Hits	183	Target Neighborhood Hits	327	Shared Neighborhood Hits	11
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

CHD4_HUMAN
θ value	4.03905 (rank : 138)	NC score	0.014150 (rank : 410)
Query Neighborhood Hits	183	Target Neighborhood Hits	365	Shared Neighborhood Hits	9
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

DAPK1_MOUSE
θ value	4.03905 (rank : 139)	NC score	0.002796 (rank : 424)
Query Neighborhood Hits	183	Target Neighborhood Hits	1138	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DLK_HUMAN
θ value	4.03905 (rank : 140)	NC score	0.149223 (rank : 130)
Query Neighborhood Hits	183	Target Neighborhood Hits	401	Shared Neighborhood Hits	96
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DNER_HUMAN
θ value	4.03905 (rank : 141)	NC score	0.145073 (rank : 136)
Query Neighborhood Hits	183	Target Neighborhood Hits	460	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

EPHB1_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.020712 (rank : 399)
Query Neighborhood Hits	183	Target Neighborhood Hits	988	Shared Neighborhood Hits	57
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

FBLN3_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.101645 (rank : 218)
Query Neighborhood Hits	183	Target Neighborhood Hits	293	Shared Neighborhood Hits	70
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

LRP3_HUMAN
θ value	4.03905 (rank : 144)	NC score	0.044862 (rank : 386)
Query Neighborhood Hits	183	Target Neighborhood Hits	280	Shared Neighborhood Hits	40
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

MIB2_HUMAN
θ value	4.03905 (rank : 145)	NC score	0.012711 (rank : 412)
Query Neighborhood Hits	183	Target Neighborhood Hits	438	Shared Neighborhood Hits	9
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

SLIT3_MOUSE
θ value	4.03905 (rank : 146)	NC score	0.095646 (rank : 239)
Query Neighborhood Hits	183	Target Neighborhood Hits	700	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TR19L_MOUSE
θ value	4.03905 (rank : 147)	NC score	0.217560 (rank : 77)
Query Neighborhood Hits	183	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TTBK2_HUMAN
θ value	4.03905 (rank : 148)	NC score	0.006592 (rank : 421)
Query Neighborhood Hits	183	Target Neighborhood Hits	822	Shared Neighborhood Hits	16
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

ADA11_HUMAN
θ value	5.27518 (rank : 149)	NC score	0.044189 (rank : 387)
Query Neighborhood Hits	183	Target Neighborhood Hits	259	Shared Neighborhood Hits	64
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	5.27518 (rank : 150)	NC score	0.044025 (rank : 388)
Query Neighborhood Hits	183	Target Neighborhood Hits	263	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CEP35_HUMAN
θ value	5.27518 (rank : 151)	NC score	0.007402 (rank : 420)
Query Neighborhood Hits	183	Target Neighborhood Hits	811	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

EGF_MOUSE
θ value	5.27518 (rank : 152)	NC score	0.096586 (rank : 235)
Query Neighborhood Hits	183	Target Neighborhood Hits	358	Shared Neighborhood Hits	80
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

ITB1_HUMAN
θ value	5.27518 (rank : 153)	NC score	0.098659 (rank : 226)
Query Neighborhood Hits	183	Target Neighborhood Hits	298	Shared Neighborhood Hits	83
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ODFP_MOUSE
θ value	5.27518 (rank : 154)	NC score	0.071269 (rank : 317)
Query Neighborhood Hits	183	Target Neighborhood Hits	75	Shared Neighborhood Hits	24
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

SDC3_MOUSE
θ value	5.27518 (rank : 155)	NC score	0.014729 (rank : 407)
Query Neighborhood Hits	183	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SORC2_HUMAN
θ value	5.27518 (rank : 156)	NC score	0.019329 (rank : 400)
Query Neighborhood Hits	183	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

TOIP2_HUMAN
θ value	5.27518 (rank : 157)	NC score	0.015057 (rank : 406)
Query Neighborhood Hits	183	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

ZAN_MOUSE
θ value	5.27518 (rank : 158)	NC score	0.170839 (rank : 110)
Query Neighborhood Hits	183	Target Neighborhood Hits	808	Shared Neighborhood Hits	127
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

AP180_MOUSE
θ value	6.88961 (rank : 159)	NC score	0.010239 (rank : 416)
Query Neighborhood Hits	183	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

CHD4_MOUSE
θ value	6.88961 (rank : 160)	NC score	0.012467 (rank : 413)
Query Neighborhood Hits	183	Target Neighborhood Hits	408	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CRUM2_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.135521 (rank : 156)
Query Neighborhood Hits	183	Target Neighborhood Hits	453	Shared Neighborhood Hits	89
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

EPHA7_MOUSE
θ value	6.88961 (rank : 162)	NC score	0.022638 (rank : 398)
Query Neighborhood Hits	183	Target Neighborhood Hits	1025	Shared Neighborhood Hits	59
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHB2_HUMAN
θ value	6.88961 (rank : 163)	NC score	0.018456 (rank : 401)
Query Neighborhood Hits	183	Target Neighborhood Hits	983	Shared Neighborhood Hits	43
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	6.88961 (rank : 164)	NC score	0.018453 (rank : 402)
Query Neighborhood Hits	183	Target Neighborhood Hits	982	Shared Neighborhood Hits	43
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

KRA56_HUMAN
θ value	6.88961 (rank : 165)	NC score	0.197692 (rank : 90)
Query Neighborhood Hits	183	Target Neighborhood Hits	207	Shared Neighborhood Hits	56
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.179665 (rank : 102)
Query Neighborhood Hits	183	Target Neighborhood Hits	269	Shared Neighborhood Hits	65
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

LIRB3_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.006102 (rank : 422)
Query Neighborhood Hits	183	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	O75022, O15471, Q86U49	Gene names	LILRB3, ILT5, LIR3
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor (Leukocyte immunoglobulin-like receptor 3) (LIR-3) (Immunoglobulin- like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD85a antigen).

THYG_HUMAN
θ value	6.88961 (rank : 168)	NC score	0.048441 (rank : 384)
Query Neighborhood Hits	183	Target Neighborhood Hits	154	Shared Neighborhood Hits	48
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

BMPER_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.090575 (rank : 257)
Query Neighborhood Hits	183	Target Neighborhood Hits	194	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CASR_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.007711 (rank : 419)
Query Neighborhood Hits	183	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

DLL4_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.149991 (rank : 128)
Query Neighborhood Hits	183	Target Neighborhood Hits	440	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DPOE1_MOUSE
θ value	8.99809 (rank : 172)	NC score	0.015666 (rank : 405)
Query Neighborhood Hits	183	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

HNF1A_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.009213 (rank : 417)
Query Neighborhood Hits	183	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

HXA10_MOUSE
θ value	8.99809 (rank : 174)	NC score	-0.001415 (rank : 426)
Query Neighborhood Hits	183	Target Neighborhood Hits	365	Shared Neighborhood Hits	2
SwissProt Accessions	P31310, Q80Y22	Gene names	Hoxa10, Hox-1.8, Hoxa-10
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1.8).

IBP7_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.017735 (rank : 403)
Query Neighborhood Hits	183	Target Neighborhood Hits	230	Shared Neighborhood Hits	13
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

KR106_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.137536 (rank : 152)
Query Neighborhood Hits	183	Target Neighborhood Hits	347	Shared Neighborhood Hits	83
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

MIB2_MOUSE
θ value	8.99809 (rank : 177)	NC score	0.008895 (rank : 418)
Query Neighborhood Hits	183	Target Neighborhood Hits	409	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MUC5B_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.093533 (rank : 245)
Query Neighborhood Hits	183	Target Neighborhood Hits	1020	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYCB2_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.013123 (rank : 411)
Query Neighborhood Hits	183	Target Neighborhood Hits	390	Shared Neighborhood Hits	16
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NMD3B_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.005794 (rank : 423)
Query Neighborhood Hits	183	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

SORL_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.073508 (rank : 310)
Query Neighborhood Hits	183	Target Neighborhood Hits	440	Shared Neighborhood Hits	74
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TR19L_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.205412 (rank : 84)
Query Neighborhood Hits	183	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

TRI56_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.017176 (rank : 404)
Query Neighborhood Hits	183	Target Neighborhood Hits	339	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

ATRN_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.139792 (rank : 149)
Query Neighborhood Hits	183	Target Neighborhood Hits	525	Shared Neighborhood Hits	86
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.143188 (rank : 140)
Query Neighborhood Hits	183	Target Neighborhood Hits	519	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BMPER_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.081278 (rank : 281)
Query Neighborhood Hits	183	Target Neighborhood Hits	175	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

C1QR1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.106685 (rank : 201)
Query Neighborhood Hits	183	Target Neighborhood Hits	493	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

CD248_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.088997 (rank : 261)
Query Neighborhood Hits	183	Target Neighborhood Hits	679	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.086180 (rank : 269)
Query Neighborhood Hits	183	Target Neighborhood Hits	578	Shared Neighborhood Hits	60
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.075398 (rank : 304)
Query Neighborhood Hits	183	Target Neighborhood Hits	353	Shared Neighborhood Hits	68
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.054204 (rank : 371)
Query Neighborhood Hits	183	Target Neighborhood Hits	295	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CELR1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.072469 (rank : 315)
Query Neighborhood Hits	183	Target Neighborhood Hits	613	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.076232 (rank : 300)
Query Neighborhood Hits	183	Target Neighborhood Hits	657	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR2_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.070611 (rank : 320)
Query Neighborhood Hits	183	Target Neighborhood Hits	584	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CELR3_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.073496 (rank : 311)
Query Neighborhood Hits	183	Target Neighborhood Hits	680	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.074795 (rank : 307)
Query Neighborhood Hits	183	Target Neighborhood Hits	687	Shared Neighborhood Hits	93
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CHRD_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.054968 (rank : 367)
Query Neighborhood Hits	183	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.055291 (rank : 363)
Query Neighborhood Hits	183	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CNTP2_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.060738 (rank : 347)
Query Neighborhood Hits	183	Target Neighborhood Hits	199	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.061663 (rank : 343)
Query Neighborhood Hits	183	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP4_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.057034 (rank : 355)
Query Neighborhood Hits	183	Target Neighborhood Hits	187	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.054435 (rank : 369)
Query Neighborhood Hits	183	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

COMP_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.108822 (rank : 196)
Query Neighborhood Hits	183	Target Neighborhood Hits	258	Shared Neighborhood Hits	80
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.117308 (rank : 186)
Query Neighborhood Hits	183	Target Neighborhood Hits	290	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CREL1_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.176104 (rank : 105)
Query Neighborhood Hits	183	Target Neighborhood Hits	441	Shared Neighborhood Hits	100
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.167891 (rank : 116)
Query Neighborhood Hits	183	Target Neighborhood Hits	524	Shared Neighborhood Hits	97
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.156191 (rank : 123)
Query Neighborhood Hits	183	Target Neighborhood Hits	362	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CRUM1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.137321 (rank : 153)
Query Neighborhood Hits	183	Target Neighborhood Hits	457	Shared Neighborhood Hits	89
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.138949 (rank : 151)
Query Neighborhood Hits	183	Target Neighborhood Hits	444	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CSPG2_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.055500 (rank : 361)
Query Neighborhood Hits	183	Target Neighborhood Hits	681	Shared Neighborhood Hits	72
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.058388 (rank : 351)
Query Neighborhood Hits	183	Target Neighborhood Hits	711	Shared Neighborhood Hits	75
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.055049 (rank : 366)
Query Neighborhood Hits	183	Target Neighborhood Hits	676	Shared Neighborhood Hits	70
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.056974 (rank : 356)
Query Neighborhood Hits	183	Target Neighborhood Hits	657	Shared Neighborhood Hits	74
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG4_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.052394 (rank : 375)
Query Neighborhood Hits	183	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CT127_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.055403 (rank : 362)
Query Neighborhood Hits	183	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CUBN_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.109924 (rank : 193)
Query Neighborhood Hits	183	Target Neighborhood Hits	482	Shared Neighborhood Hits	91
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.102565 (rank : 215)
Query Neighborhood Hits	183	Target Neighborhood Hits	477	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DLK_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.135918 (rank : 154)
Query Neighborhood Hits	183	Target Neighborhood Hits	374	Shared Neighborhood Hits	89
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.150023 (rank : 127)
Query Neighborhood Hits	183	Target Neighborhood Hits	455	Shared Neighborhood Hits	100
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.146154 (rank : 133)
Query Neighborhood Hits	183	Target Neighborhood Hits	456	Shared Neighborhood Hits	99
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.133428 (rank : 160)
Query Neighborhood Hits	183	Target Neighborhood Hits	419	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.132427 (rank : 161)
Query Neighborhood Hits	183	Target Neighborhood Hits	399	Shared Neighborhood Hits	87
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.148282 (rank : 131)
Query Neighborhood Hits	183	Target Neighborhood Hits	435	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EDIL3_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.073363 (rank : 312)
Query Neighborhood Hits	183	Target Neighborhood Hits	292	Shared Neighborhood Hits	66
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.077843 (rank : 292)
Query Neighborhood Hits	183	Target Neighborhood Hits	317	Shared Neighborhood Hits	64
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.090688 (rank : 256)
Query Neighborhood Hits	183	Target Neighborhood Hits	325	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.082714 (rank : 279)
Query Neighborhood Hits	183	Target Neighborhood Hits	287	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.078897 (rank : 287)
Query Neighborhood Hits	183	Target Neighborhood Hits	270	Shared Neighborhood Hits	55
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.073312 (rank : 313)
Query Neighborhood Hits	183	Target Neighborhood Hits	266	Shared Neighborhood Hits	51
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

EGFL9_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.130179 (rank : 167)
Query Neighborhood Hits	183	Target Neighborhood Hits	365	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.128734 (rank : 170)
Query Neighborhood Hits	183	Target Neighborhood Hits	379	Shared Neighborhood Hits	94
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGF_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.088178 (rank : 264)
Query Neighborhood Hits	183	Target Neighborhood Hits	343	Shared Neighborhood Hits	77
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EMR1_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.079860 (rank : 286)
Query Neighborhood Hits	183	Target Neighborhood Hits	382	Shared Neighborhood Hits	75
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.069206 (rank : 324)
Query Neighborhood Hits	183	Target Neighborhood Hits	349	Shared Neighborhood Hits	60
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.076200 (rank : 301)
Query Neighborhood Hits	183	Target Neighborhood Hits	345	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

ESM1_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.091626 (rank : 254)
Query Neighborhood Hits	183	Target Neighborhood Hits	110	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.083180 (rank : 276)
Query Neighborhood Hits	183	Target Neighborhood Hits	107	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FATH_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.063817 (rank : 333)
Query Neighborhood Hits	183	Target Neighborhood Hits	570	Shared Neighborhood Hits	79
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FBLN1_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.110748 (rank : 192)
Query Neighborhood Hits	183	Target Neighborhood Hits	324	Shared Neighborhood Hits	81
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.123328 (rank : 181)
Query Neighborhood Hits	183	Target Neighborhood Hits	329	Shared Neighborhood Hits	88
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN3_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.093302 (rank : 248)
Query Neighborhood Hits	183	Target Neighborhood Hits	279	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.102328 (rank : 216)
Query Neighborhood Hits	183	Target Neighborhood Hits	278	Shared Neighborhood Hits	68
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.104483 (rank : 207)
Query Neighborhood Hits	183	Target Neighborhood Hits	270	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FURIN_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.055527 (rank : 360)
Query Neighborhood Hits	183	Target Neighborhood Hits	49	Shared Neighborhood Hits	10
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

GAS6_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.106458 (rank : 202)
Query Neighborhood Hits	183	Target Neighborhood Hits	348	Shared Neighborhood Hits	76
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.104844 (rank : 205)
Query Neighborhood Hits	183	Target Neighborhood Hits	343	Shared Neighborhood Hits	77
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GRN_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.101519 (rank : 219)
Query Neighborhood Hits	183	Target Neighborhood Hits	268	Shared Neighborhood Hits	65
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.102701 (rank : 213)
Query Neighborhood Hits	183	Target Neighborhood Hits	248	Shared Neighborhood Hits	70
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HHIP_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.114746 (rank : 190)
Query Neighborhood Hits	183	Target Neighborhood Hits	249	Shared Neighborhood Hits	67
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.106699 (rank : 200)
Query Neighborhood Hits	183	Target Neighborhood Hits	219	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HMCN1_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.066269 (rank : 329)
Query Neighborhood Hits	183	Target Neighborhood Hits	983	Shared Neighborhood Hits	79
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ITB1_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.091982 (rank : 253)
Query Neighborhood Hits	183	Target Neighborhood Hits	283	Shared Neighborhood Hits	78
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.095634 (rank : 240)
Query Neighborhood Hits	183	Target Neighborhood Hits	282	Shared Neighborhood Hits	87
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.105593 (rank : 203)
Query Neighborhood Hits	183	Target Neighborhood Hits	326	Shared Neighborhood Hits	91
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.100289 (rank : 223)
Query Neighborhood Hits	183	Target Neighborhood Hits	325	Shared Neighborhood Hits	90
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.094673 (rank : 243)
Query Neighborhood Hits	183	Target Neighborhood Hits	319	Shared Neighborhood Hits	86
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB4_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.086185 (rank : 268)
Query Neighborhood Hits	183	Target Neighborhood Hits	458	Shared Neighborhood Hits	90
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.101515 (rank : 220)
Query Neighborhood Hits	183	Target Neighborhood Hits	310	Shared Neighborhood Hits	86
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.105373 (rank : 204)
Query Neighborhood Hits	183	Target Neighborhood Hits	329	Shared Neighborhood Hits	84
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.095311 (rank : 241)
Query Neighborhood Hits	183	Target Neighborhood Hits	318	Shared Neighborhood Hits	85
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.102566 (rank : 214)
Query Neighborhood Hits	183	Target Neighborhood Hits	341	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.097528 (rank : 232)
Query Neighborhood Hits	183	Target Neighborhood Hits	290	Shared Neighborhood Hits	76
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.098007 (rank : 228)
Query Neighborhood Hits	183	Target Neighborhood Hits	277	Shared Neighborhood Hits	75
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.077755 (rank : 293)
Query Neighborhood Hits	183	Target Neighborhood Hits	280	Shared Neighborhood Hits	75
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

JAG1_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.146658 (rank : 132)
Query Neighborhood Hits	183	Target Neighborhood Hits	514	Shared Neighborhood Hits	97
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.145518 (rank : 134)
Query Neighborhood Hits	183	Target Neighborhood Hits	518	Shared Neighborhood Hits	97
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.142935 (rank : 141)
Query Neighborhood Hits	183	Target Neighborhood Hits	491	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.141896 (rank : 145)
Query Neighborhood Hits	183	Target Neighborhood Hits	504	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR101_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.120065 (rank : 183)
Query Neighborhood Hits	183	Target Neighborhood Hits	261	Shared Neighborhood Hits	62
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.104258 (rank : 209)
Query Neighborhood Hits	183	Target Neighborhood Hits	264	Shared Neighborhood Hits	62
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.082882 (rank : 277)
Query Neighborhood Hits	183	Target Neighborhood Hits	212	Shared Neighborhood Hits	51
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR104_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.133699 (rank : 159)
Query Neighborhood Hits	183	Target Neighborhood Hits	313	Shared Neighborhood Hits	69
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.109349 (rank : 194)
Query Neighborhood Hits	183	Target Neighborhood Hits	271	Shared Neighborhood Hits	63
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR107_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.135738 (rank : 155)
Query Neighborhood Hits	183	Target Neighborhood Hits	330	Shared Neighborhood Hits	77
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.093136 (rank : 249)
Query Neighborhood Hits	183	Target Neighborhood Hits	226	Shared Neighborhood Hits	53
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.097000 (rank : 233)
Query Neighborhood Hits	183	Target Neighborhood Hits	226	Shared Neighborhood Hits	57
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.085524 (rank : 271)
Query Neighborhood Hits	183	Target Neighborhood Hits	232	Shared Neighborhood Hits	62
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.108089 (rank : 199)
Query Neighborhood Hits	183	Target Neighborhood Hits	269	Shared Neighborhood Hits	61
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.089493 (rank : 258)
Query Neighborhood Hits	183	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.116729 (rank : 188)
Query Neighborhood Hits	183	Target Neighborhood Hits	144	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR410_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.083653 (rank : 273)
Query Neighborhood Hits	183	Target Neighborhood Hits	156	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR412_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.076957 (rank : 296)
Query Neighborhood Hits	183	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.079952 (rank : 285)
Query Neighborhood Hits	183	Target Neighborhood Hits	199	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.170408 (rank : 111)
Query Neighborhood Hits	183	Target Neighborhood Hits	217	Shared Neighborhood Hits	52
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.145468 (rank : 135)
Query Neighborhood Hits	183	Target Neighborhood Hits	231	Shared Neighborhood Hits	56
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.096789 (rank : 234)
Query Neighborhood Hits	183	Target Neighborhood Hits	155	Shared Neighborhood Hits	38
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.090917 (rank : 255)
Query Neighborhood Hits	183	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.078636 (rank : 288)
Query Neighborhood Hits	183	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA42_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.063427 (rank : 334)
Query Neighborhood Hits	183	Target Neighborhood Hits	149	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA44_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.073557 (rank : 309)
Query Neighborhood Hits	183	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.092761 (rank : 250)
Query Neighborhood Hits	183	Target Neighborhood Hits	194	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.092067 (rank : 252)
Query Neighborhood Hits	183	Target Neighborhood Hits	204	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA55_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.188468 (rank : 100)
Query Neighborhood Hits	183	Target Neighborhood Hits	257	Shared Neighborhood Hits	67
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA92_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.086846 (rank : 267)
Query Neighborhood Hits	183	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.086088 (rank : 270)
Query Neighborhood Hits	183	Target Neighborhood Hits	203	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.089403 (rank : 259)
Query Neighborhood Hits	183	Target Neighborhood Hits	204	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.088360 (rank : 263)
Query Neighborhood Hits	183	Target Neighborhood Hits	185	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.070211 (rank : 321)
Query Neighborhood Hits	183	Target Neighborhood Hits	173	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMB2_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.240715 (rank : 64)
Query Neighborhood Hits	183	Target Neighborhood Hits	692	Shared Neighborhood Hits	112
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.217571 (rank : 76)
Query Neighborhood Hits	183	Target Neighborhood Hits	444	Shared Neighborhood Hits	84
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LCE1B_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.068051 (rank : 326)
Query Neighborhood Hits	183	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.070691 (rank : 319)
Query Neighborhood Hits	183	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1F_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.050885 (rank : 381)
Query Neighborhood Hits	183	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.057427 (rank : 354)
Query Neighborhood Hits	183	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.055995 (rank : 359)
Query Neighborhood Hits	183	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.056364 (rank : 358)
Query Neighborhood Hits	183	Target Neighborhood Hits	53	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.052634 (rank : 374)
Query Neighborhood Hits	183	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3B_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.052289 (rank : 376)
Query Neighborhood Hits	183	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LDLR_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.082875 (rank : 278)
Query Neighborhood Hits	183	Target Neighborhood Hits	382	Shared Neighborhood Hits	77
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP1B_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.109276 (rank : 195)
Query Neighborhood Hits	183	Target Neighborhood Hits	602	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.108217 (rank : 198)
Query Neighborhood Hits	183	Target Neighborhood Hits	606	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.116493 (rank : 189)
Query Neighborhood Hits	183	Target Neighborhood Hits	617	Shared Neighborhood Hits	107
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.097592 (rank : 231)
Query Neighborhood Hits	183	Target Neighborhood Hits	573	Shared Neighborhood Hits	99
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP4_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.075106 (rank : 306)
Query Neighborhood Hits	183	Target Neighborhood Hits	355	Shared Neighborhood Hits	74
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.075414 (rank : 303)
Query Neighborhood Hits	183	Target Neighborhood Hits	351	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.076716 (rank : 297)
Query Neighborhood Hits	183	Target Neighborhood Hits	346	Shared Neighborhood Hits	69
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.087046 (rank : 266)
Query Neighborhood Hits	183	Target Neighborhood Hits	385	Shared Neighborhood Hits	76
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1L_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.130238 (rank : 165)
Query Neighborhood Hits	183	Target Neighborhood Hits	553	Shared Neighborhood Hits	101
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.127546 (rank : 174)
Query Neighborhood Hits	183	Target Neighborhood Hits	514	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.129139 (rank : 169)
Query Neighborhood Hits	183	Target Neighborhood Hits	502	Shared Neighborhood Hits	94
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.127103 (rank : 176)
Query Neighborhood Hits	183	Target Neighborhood Hits	479	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.142348 (rank : 143)
Query Neighborhood Hits	183	Target Neighborhood Hits	552	Shared Neighborhood Hits	115
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.131044 (rank : 163)
Query Neighborhood Hits	183	Target Neighborhood Hits	502	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.131554 (rank : 162)
Query Neighborhood Hits	183	Target Neighborhood Hits	475	Shared Neighborhood Hits	102
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LYAM2_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.055158 (rank : 365)
Query Neighborhood Hits	183	Target Neighborhood Hits	394	Shared Neighborhood Hits	68
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.060738 (rank : 348)
Query Neighborhood Hits	183	Target Neighborhood Hits	420	Shared Neighborhood Hits	70
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.061997 (rank : 342)
Query Neighborhood Hits	183	Target Neighborhood Hits	378	Shared Neighborhood Hits	69
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.062569 (rank : 338)
Query Neighborhood Hits	183	Target Neighborhood Hits	390	Shared Neighborhood Hits	66
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MATN3_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.083523 (rank : 274)
Query Neighborhood Hits	183	Target Neighborhood Hits	268	Shared Neighborhood Hits	55
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.081314 (rank : 280)
Query Neighborhood Hits	183	Target Neighborhood Hits	261	Shared Neighborhood Hits	57
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.083402 (rank : 275)
Query Neighborhood Hits	183	Target Neighborhood Hits	287	Shared Neighborhood Hits	64
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.088787 (rank : 262)
Query Neighborhood Hits	183	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MEGF8_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.204560 (rank : 86)
Query Neighborhood Hits	183	Target Neighborhood Hits	528	Shared Neighborhood Hits	110
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 334)	NC score	0.195878 (rank : 97)
Query Neighborhood Hits	183	Target Neighborhood Hits	520	Shared Neighborhood Hits	107
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MKS3_HUMAN
θ value	θ > 10 (rank : 335)	NC score	0.067099 (rank : 327)
Query Neighborhood Hits	183	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MKS3_MOUSE
θ value	θ > 10 (rank : 336)	NC score	0.087323 (rank : 265)
Query Neighborhood Hits	183	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MT1A_HUMAN
θ value	θ > 10 (rank : 337)	NC score	0.063219 (rank : 336)
Query Neighborhood Hits	183	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

MT1B_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.059431 (rank : 350)
Query Neighborhood Hits	183	Target Neighborhood Hits	87	Shared Neighborhood Hits	27
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

MT1H_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.053326 (rank : 373)
Query Neighborhood Hits	183	Target Neighborhood Hits	78	Shared Neighborhood Hits	24
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

MT1X_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.076710 (rank : 298)
Query Neighborhood Hits	183	Target Neighborhood Hits	76	Shared Neighborhood Hits	31
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	θ > 10 (rank : 341)	NC score	0.061125 (rank : 345)
Query Neighborhood Hits	183	Target Neighborhood Hits	72	Shared Neighborhood Hits	18
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.062460 (rank : 341)
Query Neighborhood Hits	183	Target Neighborhood Hits	81	Shared Neighborhood Hits	22
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

MT3_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.072423 (rank : 316)
Query Neighborhood Hits	183	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MT3_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.118119 (rank : 185)
Query Neighborhood Hits	183	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_MOUSE
θ value	θ > 10 (rank : 345)	NC score	0.055282 (rank : 364)
Query Neighborhood Hits	183	Target Neighborhood Hits	102	Shared Neighborhood Hits	28
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

MUC2_HUMAN
θ value	θ > 10 (rank : 346)	NC score	0.062521 (rank : 340)
Query Neighborhood Hits	183	Target Neighborhood Hits	906	Shared Neighborhood Hits	75
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

NAGPA_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.127042 (rank : 177)
Query Neighborhood Hits	183	Target Neighborhood Hits	282	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.130301 (rank : 164)
Query Neighborhood Hits	183	Target Neighborhood Hits	308	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.139185 (rank : 150)
Query Neighborhood Hits	183	Target Neighborhood Hits	451	Shared Neighborhood Hits	102
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.127572 (rank : 173)
Query Neighborhood Hits	183	Target Neighborhood Hits	449	Shared Neighborhood Hits	97
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 351)	NC score	0.129516 (rank : 168)
Query Neighborhood Hits	183	Target Neighborhood Hits	436	Shared Neighborhood Hits	99
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NET1_HUMAN
θ value	θ > 10 (rank : 352)	NC score	0.196123 (rank : 95)
Query Neighborhood Hits	183	Target Neighborhood Hits	149	Shared Neighborhood Hits	54
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 353)	NC score	0.196201 (rank : 94)
Query Neighborhood Hits	183	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET2_HUMAN
θ value	θ > 10 (rank : 354)	NC score	0.200120 (rank : 88)
Query Neighborhood Hits	183	Target Neighborhood Hits	194	Shared Neighborhood Hits	63
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
θ value	θ > 10 (rank : 355)	NC score	0.199045 (rank : 89)
Query Neighborhood Hits	183	Target Neighborhood Hits	193	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

NET4_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.209336 (rank : 80)
Query Neighborhood Hits	183	Target Neighborhood Hits	191	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NET4_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.205990 (rank : 83)
Query Neighborhood Hits	183	Target Neighborhood Hits	180	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

NFX1_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.089043 (rank : 260)
Query Neighborhood Hits	183	Target Neighborhood Hits	405	Shared Neighborhood Hits	71
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NID1_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.103781 (rank : 210)
Query Neighborhood Hits	183	Target Neighborhood Hits	329	Shared Neighborhood Hits	79
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 360)	NC score	0.103046 (rank : 212)
Query Neighborhood Hits	183	Target Neighborhood Hits	335	Shared Neighborhood Hits	76
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 361)	NC score	0.108749 (rank : 197)
Query Neighborhood Hits	183	Target Neighborhood Hits	456	Shared Neighborhood Hits	88
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.096220 (rank : 238)
Query Neighborhood Hits	183	Target Neighborhood Hits	338	Shared Neighborhood Hits	77
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOTC1_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.143747 (rank : 138)
Query Neighborhood Hits	183	Target Neighborhood Hits	906	Shared Neighborhood Hits	106
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.144303 (rank : 137)
Query Neighborhood Hits	183	Target Neighborhood Hits	916	Shared Neighborhood Hits	107
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.134130 (rank : 158)
Query Neighborhood Hits	183	Target Neighborhood Hits	1113	Shared Neighborhood Hits	110
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.135313 (rank : 157)
Query Neighborhood Hits	183	Target Neighborhood Hits	1069	Shared Neighborhood Hits	105
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.143231 (rank : 139)
Query Neighborhood Hits	183	Target Neighborhood Hits	1062	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.141730 (rank : 146)
Query Neighborhood Hits	183	Target Neighborhood Hits	975	Shared Neighborhood Hits	111
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.139931 (rank : 148)
Query Neighborhood Hits	183	Target Neighborhood Hits	905	Shared Neighborhood Hits	111
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.141345 (rank : 147)
Query Neighborhood Hits	183	Target Neighborhood Hits	872	Shared Neighborhood Hits	111
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NRX1A_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.078264 (rank : 289)
Query Neighborhood Hits	183	Target Neighborhood Hits	170	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.077521 (rank : 294)
Query Neighborhood Hits	183	Target Neighborhood Hits	164	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.069999 (rank : 322)
Query Neighborhood Hits	183	Target Neighborhood Hits	614	Shared Neighborhood Hits	40
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.077272 (rank : 295)
Query Neighborhood Hits	183	Target Neighborhood Hits	164	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NTNG1_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.195790 (rank : 98)
Query Neighborhood Hits	183	Target Neighborhood Hits	247	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 376)	NC score	0.197309 (rank : 92)
Query Neighborhood Hits	183	Target Neighborhood Hits	246	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.197441 (rank : 91)
Query Neighborhood Hits	183	Target Neighborhood Hits	276	Shared Neighborhood Hits	70
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.196041 (rank : 96)
Query Neighborhood Hits	183	Target Neighborhood Hits	276	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PCSK4_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.051268 (rank : 380)
Query Neighborhood Hits	183	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PROS_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.101657 (rank : 217)
Query Neighborhood Hits	183	Target Neighborhood Hits	340	Shared Neighborhood Hits	75
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.103226 (rank : 211)
Query Neighborhood Hits	183	Target Neighborhood Hits	330	Shared Neighborhood Hits	73
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.056375 (rank : 357)
Query Neighborhood Hits	183	Target Neighborhood Hits	422	Shared Neighborhood Hits	60
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.057717 (rank : 353)
Query Neighborhood Hits	183	Target Neighborhood Hits	410	Shared Neighborhood Hits	55
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RSPO1_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.069157 (rank : 325)
Query Neighborhood Hits	183	Target Neighborhood Hits	101	Shared Neighborhood Hits	32
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO2_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.054135 (rank : 372)
Query Neighborhood Hits	183	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.054397 (rank : 370)
Query Neighborhood Hits	183	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO3_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.062558 (rank : 339)
Query Neighborhood Hits	183	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.059721 (rank : 349)
Query Neighborhood Hits	183	Target Neighborhood Hits	120	Shared Neighborhood Hits	35
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.079958 (rank : 284)
Query Neighborhood Hits	183	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.076628 (rank : 299)
Query Neighborhood Hits	183	Target Neighborhood Hits	110	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SHBG_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.069917 (rank : 323)
Query Neighborhood Hits	183	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.064263 (rank : 332)
Query Neighborhood Hits	183	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SLIT2_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.094782 (rank : 242)
Query Neighborhood Hits	183	Target Neighborhood Hits	708	Shared Neighborhood Hits	84
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.092761 (rank : 251)
Query Neighborhood Hits	183	Target Neighborhood Hits	684	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

STAB1_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.175677 (rank : 106)
Query Neighborhood Hits	183	Target Neighborhood Hits	546	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.169332 (rank : 112)
Query Neighborhood Hits	183	Target Neighborhood Hits	566	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.170976 (rank : 109)
Query Neighborhood Hits	183	Target Neighborhood Hits	534	Shared Neighborhood Hits	118
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

SUSD1_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.075171 (rank : 305)
Query Neighborhood Hits	183	Target Neighborhood Hits	285	Shared Neighborhood Hits	47
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.051400 (rank : 379)
Query Neighborhood Hits	183	Target Neighborhood Hits	146	Shared Neighborhood Hits	38
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TECTA_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.058161 (rank : 352)
Query Neighborhood Hits	183	Target Neighborhood Hits	244	Shared Neighborhood Hits	56
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TENA_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.128068 (rank : 172)
Query Neighborhood Hits	183	Target Neighborhood Hits	631	Shared Neighborhood Hits	103
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.125264 (rank : 178)
Query Neighborhood Hits	183	Target Neighborhood Hits	596	Shared Neighborhood Hits	98
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.066015 (rank : 330)
Query Neighborhood Hits	183	Target Neighborhood Hits	453	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.062872 (rank : 337)
Query Neighborhood Hits	183	Target Neighborhood Hits	484	Shared Neighborhood Hits	89
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.080370 (rank : 283)
Query Neighborhood Hits	183	Target Neighborhood Hits	526	Shared Neighborhood Hits	96
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.080508 (rank : 282)
Query Neighborhood Hits	183	Target Neighborhood Hits	531	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENX_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.130190 (rank : 166)
Query Neighborhood Hits	183	Target Neighborhood Hits	789	Shared Neighborhood Hits	106
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TIE1_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.052232 (rank : 377)
Query Neighborhood Hits	183	Target Neighborhood Hits	1241	Shared Neighborhood Hits	96
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TNR18_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.291459 (rank : 45)
Query Neighborhood Hits	183	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR18_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.201082 (rank : 87)
Query Neighborhood Hits	183	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

TNR27_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.263404 (rank : 55)
Query Neighborhood Hits	183	Target Neighborhood Hits	69	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TNR27_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.232528 (rank : 68)
Query Neighborhood Hits	183	Target Neighborhood Hits	61	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

TRBM_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.117261 (rank : 187)
Query Neighborhood Hits	183	Target Neighborhood Hits	339	Shared Neighborhood Hits	73
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSP1_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.073010 (rank : 314)
Query Neighborhood Hits	183	Target Neighborhood Hits	389	Shared Neighborhood Hits	81
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.075699 (rank : 302)
Query Neighborhood Hits	183	Target Neighborhood Hits	396	Shared Neighborhood Hits	83
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.060765 (rank : 346)
Query Neighborhood Hits	183	Target Neighborhood Hits	359	Shared Neighborhood Hits	74
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.065168 (rank : 331)
Query Neighborhood Hits	183	Target Neighborhood Hits	352	Shared Neighborhood Hits	76
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.096281 (rank : 237)
Query Neighborhood Hits	183	Target Neighborhood Hits	250	Shared Neighborhood Hits	73
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.099997 (rank : 224)
Query Neighborhood Hits	183	Target Neighborhood Hits	247	Shared Neighborhood Hits	74
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.097709 (rank : 230)
Query Neighborhood Hits	183	Target Neighborhood Hits	277	Shared Neighborhood Hits	73
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.100638 (rank : 222)
Query Neighborhood Hits	183	Target Neighborhood Hits	276	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROM_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.097953 (rank : 229)
Query Neighborhood Hits	183	Target Neighborhood Hits	284	Shared Neighborhood Hits	70
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.099480 (rank : 225)
Query Neighborhood Hits	183	Target Neighborhood Hits	276	Shared Neighborhood Hits	76
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VLDLR_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.094107 (rank : 244)
Query Neighborhood Hits	183	Target Neighborhood Hits	383	Shared Neighborhood Hits	83
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.093482 (rank : 246)
Query Neighborhood Hits	183	Target Neighborhood Hits	360	Shared Neighborhood Hits	79
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VWF_MOUSE
θ value	θ > 10 (rank : 426)	NC score	0.084342 (rank : 272)
Query Neighborhood Hits	183	Target Neighborhood Hits	381	Shared Neighborhood Hits	89
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ZAN_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.070989 (rank : 318)
Query Neighborhood Hits	183	Target Neighborhood Hits	679	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

TNR16_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	183	Target Neighborhood Hits	183	Shared Neighborhood Hits	183
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
NC score	0.972067 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	183	Target Neighborhood Hits	178	Shared Neighborhood Hits	140
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR14_HUMAN
NC score	0.746085 (rank : 3)	θ value	1.58096e-12 (rank : 6)
Query Neighborhood Hits	183	Target Neighborhood Hits	149	Shared Neighborhood Hits	91
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR26_MOUSE
NC score	0.739504 (rank : 4)	θ value	1.58096e-12 (rank : 7)
Query Neighborhood Hits	183	Target Neighborhood Hits	106	Shared Neighborhood Hits	67
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR23_MOUSE
NC score	0.738600 (rank : 5)	θ value	3.52202e-12 (rank : 8)
Query Neighborhood Hits	183	Target Neighborhood Hits	114	Shared Neighborhood Hits	80
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR22_MOUSE
NC score	0.734872 (rank : 6)	θ value	4.59992e-12 (rank : 10)
Query Neighborhood Hits	183	Target Neighborhood Hits	97	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR5_MOUSE
NC score	0.715712 (rank : 7)	θ value	1.29331e-14 (rank : 3)
Query Neighborhood Hits	183	Target Neighborhood Hits	131	Shared Neighborhood Hits	75
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

TNR4_HUMAN
NC score	0.706537 (rank : 8)	θ value	3.52202e-12 (rank : 9)
Query Neighborhood Hits	183	Target Neighborhood Hits	152	Shared Neighborhood Hits	86
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

TR11B_MOUSE
NC score	0.686589 (rank : 9)	θ value	6.41864e-14 (rank : 4)
Query Neighborhood Hits	183	Target Neighborhood Hits	95	Shared Neighborhood Hits	66
SwissProt Accessions	O08712, O70202	Gene names	Tnfrsf11b, Ocif, Opg
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR4_MOUSE
NC score	0.686105 (rank : 10)	θ value	1.80886e-08 (rank : 21)
Query Neighborhood Hits	183	Target Neighborhood Hits	137	Shared Neighborhood Hits	90
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TNR5_HUMAN
NC score	0.686013 (rank : 11)	θ value	7.84624e-12 (rank : 12)
Query Neighborhood Hits	183	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TR11B_HUMAN
NC score	0.685053 (rank : 12)	θ value	1.2105e-12 (rank : 5)
Query Neighborhood Hits	183	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	O00300, O60236, Q53FX6, Q9UHP4	Gene names	TNFRSF11B, OCIF, OPG
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11B precursor (Osteoprotegerin) (Osteoclastogenesis inhibitory factor).

TNR1B_HUMAN
NC score	0.678477 (rank : 13)	θ value	7.84624e-12 (rank : 11)
Query Neighborhood Hits	183	Target Neighborhood Hits	127	Shared Neighborhood Hits	70
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

TNR6B_HUMAN
NC score	0.670736 (rank : 14)	θ value	4.76016e-09 (rank : 20)
Query Neighborhood Hits	183	Target Neighborhood Hits	103	Shared Neighborhood Hits	70
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR1B_MOUSE
NC score	0.652156 (rank : 15)	θ value	2.52405e-10 (rank : 14)
Query Neighborhood Hits	183	Target Neighborhood Hits	123	Shared Neighborhood Hits	60
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

TNR3_HUMAN
NC score	0.640604 (rank : 16)	θ value	5.81887e-07 (rank : 24)
Query Neighborhood Hits	183	Target Neighborhood Hits	145	Shared Neighborhood Hits	78
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR11_HUMAN
NC score	0.634182 (rank : 17)	θ value	9.59137e-10 (rank : 18)
Query Neighborhood Hits	183	Target Neighborhood Hits	135	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
NC score	0.625284 (rank : 18)	θ value	3.64472e-09 (rank : 19)
Query Neighborhood Hits	183	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR6_MOUSE
NC score	0.623934 (rank : 19)	θ value	2.61198e-07 (rank : 23)
Query Neighborhood Hits	183	Target Neighborhood Hits	99	Shared Neighborhood Hits	64
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR3_MOUSE
NC score	0.615728 (rank : 20)	θ value	2.44474e-05 (rank : 33)
Query Neighborhood Hits	183	Target Neighborhood Hits	113	Shared Neighborhood Hits	79
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR1A_HUMAN
NC score	0.614230 (rank : 21)	θ value	1.33837e-11 (rank : 13)
Query Neighborhood Hits	183	Target Neighborhood Hits	121	Shared Neighborhood Hits	66
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR21_HUMAN
NC score	0.603348 (rank : 22)	θ value	7.34386e-10 (rank : 17)
Query Neighborhood Hits	183	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	O75509, Q96D86	Gene names	TNFRSF21, DR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR1A_MOUSE
NC score	0.600368 (rank : 23)	θ value	0.00020696 (rank : 42)
Query Neighborhood Hits	183	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR21_MOUSE
NC score	0.598609 (rank : 24)	θ value	2.52405e-10 (rank : 15)
Query Neighborhood Hits	183	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TR10C_HUMAN
NC score	0.592624 (rank : 25)	θ value	4.30538e-10 (rank : 16)
Query Neighborhood Hits	183	Target Neighborhood Hits	105	Shared Neighborhood Hits	53
SwissProt Accessions	O14798, O14755, Q6UXM5	Gene names	TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10C precursor (Decoy receptor 1) (DcR1) (Decoy TRAIL receptor without death domain) (TNF- related apoptosis-inducing ligand receptor 3) (TRAIL receptor 3) (TRAIL-R3) (Trail receptor without an intracellular domain) (Lymphocyte inhibitor of TRAIL) (Antagonist decoy receptor for TRAIL/Apo-2L) (CD263 antigen).

TNR7_HUMAN
NC score	0.579691 (rank : 26)	θ value	1.29631e-06 (rank : 26)
Query Neighborhood Hits	183	Target Neighborhood Hits	120	Shared Neighborhood Hits	71
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR6_HUMAN
NC score	0.571425 (rank : 27)	θ value	2.61198e-07 (rank : 22)
Query Neighborhood Hits	183	Target Neighborhood Hits	95	Shared Neighborhood Hits	60
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR9_MOUSE
NC score	0.566833 (rank : 28)	θ value	0.000270298 (rank : 43)
Query Neighborhood Hits	183	Target Neighborhood Hits	137	Shared Neighborhood Hits	81
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

TNR7_MOUSE
NC score	0.544722 (rank : 29)	θ value	1.09739e-05 (rank : 30)
Query Neighborhood Hits	183	Target Neighborhood Hits	112	Shared Neighborhood Hits	62
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR9_HUMAN
NC score	0.544469 (rank : 30)	θ value	0.000158464 (rank : 39)
Query Neighborhood Hits	183	Target Neighborhood Hits	166	Shared Neighborhood Hits	86
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TNR25_HUMAN
NC score	0.528311 (rank : 31)	θ value	0.0431538 (rank : 68)
Query Neighborhood Hits	183	Target Neighborhood Hits	172	Shared Neighborhood Hits	88
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR8_HUMAN
NC score	0.527873 (rank : 32)	θ value	0.000461057 (rank : 45)
Query Neighborhood Hits	183	Target Neighborhood Hits	198	Shared Neighborhood Hits	82
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TR10B_HUMAN
NC score	0.516810 (rank : 33)	θ value	6.43352e-06 (rank : 29)
Query Neighborhood Hits	183	Target Neighborhood Hits	71	Shared Neighborhood Hits	56
SwissProt Accessions	O14763, O14720, O15508, O15517, O15531, Q9BVE0	Gene names	TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD262 antigen).

TR10B_MOUSE
NC score	0.516499 (rank : 34)	θ value	1.87187e-05 (rank : 32)
Query Neighborhood Hits	183	Target Neighborhood Hits	76	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TR10D_HUMAN
NC score	0.514564 (rank : 35)	θ value	5.81887e-07 (rank : 25)
Query Neighborhood Hits	183	Target Neighborhood Hits	62	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UBN6, Q9Y6Q4	Gene names	TNFRSF10D, DCR2, TRAILR4, TRUNDD
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10D precursor (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD264 antigen).

TR10A_HUMAN
NC score	0.495244 (rank : 36)	θ value	4.1701e-05 (rank : 35)
Query Neighborhood Hits	183	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	O00220, Q96E62	Gene names	TNFRSF10A, APO2, DR4, TRAILR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10A precursor (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD261 antigen).

TNR8_MOUSE
NC score	0.454796 (rank : 37)	θ value	0.00228821 (rank : 53)
Query Neighborhood Hits	183	Target Neighborhood Hits	208	Shared Neighborhood Hits	70
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR19_MOUSE
NC score	0.322903 (rank : 38)	θ value	0.00228821 (rank : 52)
Query Neighborhood Hits	183	Target Neighborhood Hits	100	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

LAMC3_HUMAN
NC score	0.308179 (rank : 39)	θ value	2.88788e-06 (rank : 27)
Query Neighborhood Hits	183	Target Neighborhood Hits	588	Shared Neighborhood Hits	127
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
NC score	0.307750 (rank : 40)	θ value	0.000158464 (rank : 38)
Query Neighborhood Hits	183	Target Neighborhood Hits	624	Shared Neighborhood Hits	122
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA5_MOUSE
NC score	0.305281 (rank : 41)	θ value	9.29e-05 (rank : 37)
Query Neighborhood Hits	183	Target Neighborhood Hits	828	Shared Neighborhood Hits	138
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_HUMAN
NC score	0.302688 (rank : 42)	θ value	4.1701e-05 (rank : 34)
Query Neighborhood Hits	183	Target Neighborhood Hits	976	Shared Neighborhood Hits	140
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC2_MOUSE
NC score	0.295532 (rank : 43)	θ value	0.0148317 (rank : 59)
Query Neighborhood Hits	183	Target Neighborhood Hits	614	Shared Neighborhood Hits	130
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMA1_HUMAN
NC score	0.294375 (rank : 44)	θ value	0.000602161 (rank : 46)
Query Neighborhood Hits	183	Target Neighborhood Hits	804	Shared Neighborhood Hits	124
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

TNR18_HUMAN
NC score	0.291459 (rank : 45)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	183	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

LAMA1_MOUSE
NC score	0.290102 (rank : 46)	θ value	9.29e-05 (rank : 36)
Query Neighborhood Hits	183	Target Neighborhood Hits	838	Shared Neighborhood Hits	127
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

MEGF9_HUMAN
NC score	0.281823 (rank : 47)	θ value	0.0563607 (rank : 71)
Query Neighborhood Hits	183	Target Neighborhood Hits	557	Shared Neighborhood Hits	117
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
NC score	0.277905 (rank : 48)	θ value	0.47712 (rank : 92)
Query Neighborhood Hits	183	Target Neighborhood Hits	896	Shared Neighborhood Hits	117
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMA4_MOUSE
NC score	0.277259 (rank : 49)	θ value	1.87187e-05 (rank : 31)
Query Neighborhood Hits	183	Target Neighborhood Hits	584	Shared Neighborhood Hits	79
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMC2_HUMAN
NC score	0.275905 (rank : 50)	θ value	0.0252991 (rank : 64)
Query Neighborhood Hits	183	Target Neighborhood Hits	715	Shared Neighborhood Hits	119
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC1_MOUSE
NC score	0.275200 (rank : 51)	θ value	0.000461057 (rank : 44)
Query Neighborhood Hits	183	Target Neighborhood Hits	856	Shared Neighborhood Hits	124
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_HUMAN
NC score	0.273213 (rank : 52)	θ value	0.000602161 (rank : 47)
Query Neighborhood Hits	183	Target Neighborhood Hits	922	Shared Neighborhood Hits	122
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA3_MOUSE
NC score	0.266602 (rank : 53)	θ value	0.365318 (rank : 89)
Query Neighborhood Hits	183	Target Neighborhood Hits	859	Shared Neighborhood Hits	124
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA2_HUMAN
NC score	0.266237 (rank : 54)	θ value	0.00665767 (rank : 55)
Query Neighborhood Hits	183	Target Neighborhood Hits	1092	Shared Neighborhood Hits	123
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

TNR27_HUMAN
NC score	0.263404 (rank : 55)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	183	Target Neighborhood Hits	69	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HAV5, Q6UWM2, Q8IZA6	Gene names	EDA2R, TNFRSF27, XEDAR
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

PCSK5_MOUSE
NC score	0.262865 (rank : 56)	θ value	0.00020696 (rank : 41)
Query Neighborhood Hits	183	Target Neighborhood Hits	613	Shared Neighborhood Hits	142
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

LAMA4_HUMAN
NC score	0.262208 (rank : 57)	θ value	4.92598e-06 (rank : 28)
Query Neighborhood Hits	183	Target Neighborhood Hits	708	Shared Neighborhood Hits	77
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA3_HUMAN
NC score	0.260795 (rank : 58)	θ value	0.0563607 (rank : 70)
Query Neighborhood Hits	183	Target Neighborhood Hits	760	Shared Neighborhood Hits	99
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

TNR19_HUMAN
NC score	0.254099 (rank : 59)	θ value	0.163984 (rank : 84)
Query Neighborhood Hits	183	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

LAMA2_MOUSE
NC score	0.251677 (rank : 60)	θ value	0.00102713 (rank : 49)
Query Neighborhood Hits	183	Target Neighborhood Hits	1198	Shared Neighborhood Hits	115
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB2_MOUSE
NC score	0.251441 (rank : 61)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	183	Target Neighborhood Hits	722	Shared Neighborhood Hits	118
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB1_MOUSE
NC score	0.244528 (rank : 62)	θ value	0.0148317 (rank : 58)
Query Neighborhood Hits	183	Target Neighborhood Hits	919	Shared Neighborhood Hits	119
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KRA54_HUMAN
NC score	0.242657 (rank : 63)	θ value	0.00228821 (rank : 51)
Query Neighborhood Hits	183	Target Neighborhood Hits	270	Shared Neighborhood Hits	64
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

LAMB2_HUMAN
NC score	0.240715 (rank : 64)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	183	Target Neighborhood Hits	692	Shared Neighborhood Hits	112
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB1_HUMAN
NC score	0.235496 (rank : 65)	θ value	0.0193708 (rank : 62)
Query Neighborhood Hits	183	Target Neighborhood Hits	1018	Shared Neighborhood Hits	114
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SREC_HUMAN
NC score	0.235342 (rank : 66)	θ value	0.0193708 (rank : 63)
Query Neighborhood Hits	183	Target Neighborhood Hits	645	Shared Neighborhood Hits	125
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

USH2A_MOUSE
NC score	0.233163 (rank : 67)	θ value	0.125558 (rank : 80)
Query Neighborhood Hits	183	Target Neighborhood Hits	626	Shared Neighborhood Hits	117
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

TNR27_MOUSE
NC score	0.232528 (rank : 68)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	183	Target Neighborhood Hits	61	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BX35, Q8BM50	Gene names	Eda2r, Tnfrsf27, Xedar
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor).

SREC2_HUMAN
NC score	0.226038 (rank : 69)	θ value	0.62314 (rank : 99)
Query Neighborhood Hits	183	Target Neighborhood Hits	645	Shared Neighborhood Hits	112
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

USH2A_HUMAN
NC score	0.225725 (rank : 70)	θ value	0.0961366 (rank : 78)
Query Neighborhood Hits	183	Target Neighborhood Hits	600	Shared Neighborhood Hits	118
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

FRAS1_HUMAN
NC score	0.225326 (rank : 71)	θ value	0.00020696 (rank : 40)
Query Neighborhood Hits	183	Target Neighborhood Hits	759	Shared Neighborhood Hits	136
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KRA59_HUMAN
NC score	0.223427 (rank : 72)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	183	Target Neighborhood Hits	310	Shared Neighborhood Hits	80
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA51_HUMAN
NC score	0.223375 (rank : 73)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	183	Target Neighborhood Hits	288	Shared Neighborhood Hits	77
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

SREC2_MOUSE
NC score	0.219882 (rank : 74)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	183	Target Neighborhood Hits	605	Shared Neighborhood Hits	116
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

LAMB3_HUMAN
NC score	0.219845 (rank : 75)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	183	Target Neighborhood Hits	461	Shared Neighborhood Hits	81
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
NC score	0.217571 (rank : 76)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	183	Target Neighborhood Hits	444	Shared Neighborhood Hits	84
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

TR19L_MOUSE
NC score	0.217560 (rank : 77)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	183	Target Neighborhood Hits	85	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

FRAS1_MOUSE
NC score	0.214191 (rank : 78)	θ value	0.000786445 (rank : 48)
Query Neighborhood Hits	183	Target Neighborhood Hits	747	Shared Neighborhood Hits	127
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MEGF6_HUMAN
NC score	0.212832 (rank : 79)	θ value	0.279714 (rank : 86)
Query Neighborhood Hits	183	Target Neighborhood Hits	671	Shared Neighborhood Hits	127
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NET4_HUMAN
NC score	0.209336 (rank : 80)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	183	Target Neighborhood Hits	191	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

KRA53_HUMAN
NC score	0.208394 (rank : 81)	θ value	0.62314 (rank : 98)
Query Neighborhood Hits	183	Target Neighborhood Hits	331	Shared Neighborhood Hits	83
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA52_HUMAN
NC score	0.207987 (rank : 82)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	183	Target Neighborhood Hits	236	Shared Neighborhood Hits	60
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

NET4_MOUSE
NC score	0.205990 (rank : 83)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	183	Target Neighborhood Hits	180	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

TR19L_HUMAN
NC score	0.205412 (rank : 84)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	183	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

KRA58_HUMAN
NC score	0.204950 (rank : 85)	θ value	0.0193708 (rank : 61)
Query Neighborhood Hits	183	Target Neighborhood Hits	324	Shared Neighborhood Hits	77
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

MEGF8_HUMAN
NC score	0.204560 (rank : 86)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	183	Target Neighborhood Hits	528	Shared Neighborhood Hits	110
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TNR18_MOUSE
NC score	0.201082 (rank : 87)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	183	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

NET2_HUMAN
NC score	0.200120 (rank : 88)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	183	Target Neighborhood Hits	194	Shared Neighborhood Hits	63
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
NC score	0.199045 (rank : 89)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	183	Target Neighborhood Hits	193	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

KRA56_HUMAN
NC score	0.197692 (rank : 90)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	183	Target Neighborhood Hits	207	Shared Neighborhood Hits	56
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

NTNG2_HUMAN
NC score	0.197441 (rank : 91)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	183	Target Neighborhood Hits	276	Shared Neighborhood Hits	70
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG1_MOUSE
NC score	0.197309 (rank : 92)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	183	Target Neighborhood Hits	246	Shared Neighborhood Hits	74
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

AGRIN_HUMAN
NC score	0.196959 (rank : 93)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	183	Target Neighborhood Hits	582	Shared Neighborhood Hits	97
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

NET1_MOUSE
NC score	0.196201 (rank : 94)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	183	Target Neighborhood Hits	151	Shared Neighborhood Hits	54
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NET1_HUMAN
NC score	0.196123 (rank : 95)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	183	Target Neighborhood Hits	149	Shared Neighborhood Hits	54
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NTNG2_MOUSE
NC score	0.196041 (rank : 96)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	183	Target Neighborhood Hits	276	Shared Neighborhood Hits	71
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

MEGF8_MOUSE
NC score	0.195878 (rank : 97)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	183	Target Neighborhood Hits	520	Shared Neighborhood Hits	107
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NTNG1_HUMAN
NC score	0.195790 (rank : 98)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	183	Target Neighborhood Hits	247	Shared Neighborhood Hits	71
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PGBM_MOUSE
NC score	0.188827 (rank : 99)	θ value	0.00509761 (rank : 54)
Query Neighborhood Hits	183	Target Neighborhood Hits	1073	Shared Neighborhood Hits	122
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

KRA55_HUMAN
NC score	0.188468 (rank : 100)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	183	Target Neighborhood Hits	257	Shared Neighborhood Hits	67
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

STAB2_MOUSE
NC score	0.184293 (rank : 101)	θ value	0.0330416 (rank : 66)
Query Neighborhood Hits	183	Target Neighborhood Hits	528	Shared Neighborhood Hits	118
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

KRA57_HUMAN
NC score	0.179665 (rank : 102)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	183	Target Neighborhood Hits	269	Shared Neighborhood Hits	65
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

SCUB3_MOUSE
NC score	0.179104 (rank : 103)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	183	Target Neighborhood Hits	442	Shared Neighborhood Hits	132
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

PGBM_HUMAN
NC score	0.176474 (rank : 104)	θ value	0.0148317 (rank : 60)
Query Neighborhood Hits	183	Target Neighborhood Hits	1113	Shared Neighborhood Hits	114
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

CREL1_HUMAN
NC score	0.176104 (rank : 105)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	183	Target Neighborhood Hits	441	Shared Neighborhood Hits	100
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

STAB1_HUMAN
NC score	0.175677 (rank : 106)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	183	Target Neighborhood Hits	546	Shared Neighborhood Hits	118
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

PCSK5_HUMAN
NC score	0.174465 (rank : 107)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	183	Target Neighborhood Hits	291	Shared Neighborhood Hits	101
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

SCUB3_HUMAN
NC score	0.171151 (rank : 108)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	183	Target Neighborhood Hits	428	Shared Neighborhood Hits	128
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

STAB2_HUMAN
NC score	0.170976 (rank : 109)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	183	Target Neighborhood Hits	534	Shared Neighborhood Hits	118
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

ZAN_MOUSE
NC score	0.170839 (rank : 110)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	183	Target Neighborhood Hits	808	Shared Neighborhood Hits	127
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KR510_HUMAN
NC score	0.170408 (rank : 111)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	183	Target Neighborhood Hits	217	Shared Neighborhood Hits	52
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

STAB1_MOUSE
NC score	0.169332 (rank : 112)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	183	Target Neighborhood Hits	566	Shared Neighborhood Hits	117
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

FBN1_HUMAN
NC score	0.168375 (rank : 113)	θ value	0.0563607 (rank : 69)
Query Neighborhood Hits	183	Target Neighborhood Hits	557	Shared Neighborhood Hits	115
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
NC score	0.168021 (rank : 114)	θ value	0.00134147 (rank : 50)
Query Neighborhood Hits	183	Target Neighborhood Hits	549	Shared Neighborhood Hits	109
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.167991 (rank : 115)	θ value	0.0736092 (rank : 74)
Query Neighborhood Hits	183	Target Neighborhood Hits	563	Shared Neighborhood Hits	113
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

CREL1_MOUSE
NC score	0.167891 (rank : 116)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	183	Target Neighborhood Hits	524	Shared Neighborhood Hits	97
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

FBN3_HUMAN
NC score	0.165848 (rank : 117)	θ value	0.279714 (rank : 85)
Query Neighborhood Hits	183	Target Neighborhood Hits	543	Shared Neighborhood Hits	112
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

PCSK6_HUMAN
NC score	0.165426 (rank : 118)	θ value	0.0431538 (rank : 67)
Query Neighborhood Hits	183	Target Neighborhood Hits	298	Shared Neighborhood Hits	87
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

FBN2_HUMAN
NC score	0.165006 (rank : 119)	θ value	0.00869519 (rank : 56)
Query Neighborhood Hits	183	Target Neighborhood Hits	560	Shared Neighborhood Hits	111
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

EDAR_HUMAN
NC score	0.162289 (rank : 120)	θ value	0.62314 (rank : 96)
Query Neighborhood Hits	183	Target Neighborhood Hits	84	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UNE0, Q9UND9	Gene names	EDAR, DL
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (EDA- A1 receptor) (Ectodermal dysplasia receptor) (Downless homolog).

WIF1_MOUSE
NC score	0.161086 (rank : 121)	θ value	0.279714 (rank : 87)
Query Neighborhood Hits	183	Target Neighborhood Hits	393	Shared Neighborhood Hits	94
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_HUMAN
NC score	0.157353 (rank : 122)	θ value	0.0563607 (rank : 72)
Query Neighborhood Hits	183	Target Neighborhood Hits	392	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CRIM1_HUMAN
NC score	0.156191 (rank : 123)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	183	Target Neighborhood Hits	362	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

EDAR_MOUSE
NC score	0.154427 (rank : 124)	θ value	0.62314 (rank : 97)
Query Neighborhood Hits	183	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R187, Q9DC43	Gene names	Edar, Dl
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member EDAR precursor (Anhidrotic ectodysplasin receptor 1) (Ectodysplasin-A receptor) (Ectodermal dysplasia receptor) (Downless).

DNER_MOUSE
NC score	0.151579 (rank : 125)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	183	Target Neighborhood Hits	413	Shared Neighborhood Hits	86
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

LTBP4_MOUSE
NC score	0.150593 (rank : 126)	θ value	0.47712 (rank : 91)
Query Neighborhood Hits	183	Target Neighborhood Hits	607	Shared Neighborhood Hits	105
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

DLL1_HUMAN
NC score	0.150023 (rank : 127)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	183	Target Neighborhood Hits	455	Shared Neighborhood Hits	100
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL4_MOUSE
NC score	0.149991 (rank : 128)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	183	Target Neighborhood Hits	440	Shared Neighborhood Hits	101
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

LTBP2_MOUSE
NC score	0.149878 (rank : 129)	θ value	0.0330416 (rank : 65)
Query Neighborhood Hits	183	Target Neighborhood Hits	617	Shared Neighborhood Hits	112
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

DLK_HUMAN
NC score	0.149223 (rank : 130)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	183	Target Neighborhood Hits	401	Shared Neighborhood Hits	96
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL4_HUMAN
NC score	0.148282 (rank : 131)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	183	Target Neighborhood Hits	435	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

JAG1_HUMAN
NC score	0.146658 (rank : 132)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	183	Target Neighborhood Hits	514	Shared Neighborhood Hits	97
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

DLL1_MOUSE
NC score	0.146154 (rank : 133)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	183	Target Neighborhood Hits	456	Shared Neighborhood Hits	99
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

JAG1_MOUSE
NC score	0.145518 (rank : 134)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	183	Target Neighborhood Hits	518	Shared Neighborhood Hits	97
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

KR511_HUMAN
NC score	0.145468 (rank : 135)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	183	Target Neighborhood Hits	231	Shared Neighborhood Hits	56
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

DNER_HUMAN
NC score	0.145073 (rank : 136)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	183	Target Neighborhood Hits	460	Shared Neighborhood Hits	85
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

NOTC1_MOUSE
NC score	0.144303 (rank : 137)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	183	Target Neighborhood Hits	916	Shared Neighborhood Hits	107
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_HUMAN
NC score	0.143747 (rank : 138)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	183	Target Neighborhood Hits	906	Shared Neighborhood Hits	106
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
NC score	0.143231 (rank : 139)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	183	Target Neighborhood Hits	1062	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ATRN_MOUSE
NC score	0.143188 (rank : 140)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	183	Target Neighborhood Hits	519	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

JAG2_HUMAN
NC score	0.142935 (rank : 141)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	183	Target Neighborhood Hits	491	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

FBLN2_HUMAN
NC score	0.142562 (rank : 142)	θ value	0.0148317 (rank : 57)
Query Neighborhood Hits	183	Target Neighborhood Hits	392	Shared Neighborhood Hits	85
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LTBP2_HUMAN
NC score	0.142348 (rank : 143)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	183	Target Neighborhood Hits	552	Shared Neighborhood Hits	115
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TRBM_MOUSE
NC score	0.142009 (rank : 144)	θ value	0.0736092 (rank : 75)
Query Neighborhood Hits	183	Target Neighborhood Hits	361	Shared Neighborhood Hits	89
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

JAG2_MOUSE
NC score	0.141896 (rank : 145)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	183	Target Neighborhood Hits	504	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

NOTC3_MOUSE
NC score	0.141730 (rank : 146)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	183	Target Neighborhood Hits	975	Shared Neighborhood Hits	111
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
NC score	0.141345 (rank : 147)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	183	Target Neighborhood Hits	872	Shared Neighborhood Hits	111
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC4_HUMAN
NC score	0.139931 (rank : 148)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	183	Target Neighborhood Hits	905	Shared Neighborhood Hits	111
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ATRN_HUMAN
NC score	0.139792 (rank : 149)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	183	Target Neighborhood Hits	525	Shared Neighborhood Hits	86
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

NELL1_HUMAN
NC score	0.139185 (rank : 150)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	183	Target Neighborhood Hits	451	Shared Neighborhood Hits	102
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

CRUM1_MOUSE
NC score	0.138949 (rank : 151)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	183	Target Neighborhood Hits	444	Shared Neighborhood Hits	86
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

KR106_HUMAN
NC score	0.137536 (rank : 152)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	183	Target Neighborhood Hits	347	Shared Neighborhood Hits	83
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

CRUM1_HUMAN
NC score	0.137321 (rank : 153)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	183	Target Neighborhood Hits	457	Shared Neighborhood Hits	89
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DLK_MOUSE
NC score	0.135918 (rank : 154)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	183	Target Neighborhood Hits	374	Shared Neighborhood Hits	89
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

KR107_HUMAN
NC score	0.135738 (rank : 155)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	183	Target Neighborhood Hits	330	Shared Neighborhood Hits	77
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

CRUM2_HUMAN
NC score	0.135521 (rank : 156)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	183	Target Neighborhood Hits	453	Shared Neighborhood Hits	89
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

NOTC2_MOUSE
NC score	0.135313 (rank : 157)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	183	Target Neighborhood Hits	1069	Shared Neighborhood Hits	105
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.134130 (rank : 158)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	183	Target Neighborhood Hits	1113	Shared Neighborhood Hits	110
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KR104_HUMAN
NC score	0.133699 (rank : 159)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	183	Target Neighborhood Hits	313	Shared Neighborhood Hits	69
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

DLL3_HUMAN
NC score	0.133428 (rank : 160)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	183	Target Neighborhood Hits	419	Shared Neighborhood Hits	85
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
NC score	0.132427 (rank : 161)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	183	Target Neighborhood Hits	399	Shared Neighborhood Hits	87
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

LTBP3_MOUSE
NC score	0.131554 (rank : 162)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	183	Target Neighborhood Hits	475	Shared Neighborhood Hits	102
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_HUMAN
NC score	0.131044 (rank : 163)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	183	Target Neighborhood Hits	502	Shared Neighborhood Hits	99
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NAGPA_MOUSE
NC score	0.130301 (rank : 164)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	183	Target Neighborhood Hits	308	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

LTB1L_HUMAN
NC score	0.130238 (rank : 165)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	183	Target Neighborhood Hits	553	Shared Neighborhood Hits	101
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TENX_HUMAN
NC score	0.130190 (rank : 166)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	183	Target Neighborhood Hits	789	Shared Neighborhood Hits	106
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

EGFL9_HUMAN
NC score	0.130179 (rank : 167)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	183	Target Neighborhood Hits	365	Shared Neighborhood Hits	90
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

NELL2_MOUSE
NC score	0.129516 (rank : 168)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	183	Target Neighborhood Hits	436	Shared Neighborhood Hits	99
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

LTB1S_HUMAN
NC score	0.129139 (rank : 169)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	183	Target Neighborhood Hits	502	Shared Neighborhood Hits	94
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

EGFL9_MOUSE
NC score	0.128734 (rank : 170)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	183	Target Neighborhood Hits	379	Shared Neighborhood Hits	94
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

FBLN2_MOUSE
NC score	0.128127 (rank : 171)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	183	Target Neighborhood Hits	505	Shared Neighborhood Hits	88
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

TENA_HUMAN
NC score	0.128068 (rank : 172)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	183	Target Neighborhood Hits	631	Shared Neighborhood Hits	103
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

NELL2_HUMAN
NC score	0.127572 (rank : 173)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	183	Target Neighborhood Hits	449	Shared Neighborhood Hits	97
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

LTB1L_MOUSE
NC score	0.127546 (rank : 174)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	183	Target Neighborhood Hits	514	Shared Neighborhood Hits	100
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN5_HUMAN
NC score	0.127185 (rank : 175)	θ value	0.163984 (rank : 81)
Query Neighborhood Hits	183	Target Neighborhood Hits	329	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

LTB1S_MOUSE
NC score	0.127103 (rank : 176)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	183	Target Neighborhood Hits	479	Shared Neighborhood Hits	94
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NAGPA_HUMAN
NC score	0.127042 (rank : 177)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	183	Target Neighborhood Hits	282	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

TENA_MOUSE
NC score	0.125264 (rank : 178)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	183	Target Neighborhood Hits	596	Shared Neighborhood Hits	98
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

MATN2_HUMAN
NC score	0.124684 (rank : 179)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	183	Target Neighborhood Hits	365	Shared Neighborhood Hits	77
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

MATN2_MOUSE
NC score	0.124097 (rank : 180)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	183	Target Neighborhood Hits	356	Shared Neighborhood Hits	77
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

FBLN1_MOUSE
NC score	0.123328 (rank : 181)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	183	Target Neighborhood Hits	329	Shared Neighborhood Hits	88
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN5_MOUSE
NC score	0.121000 (rank : 182)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	183	Target Neighborhood Hits	317	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

KR101_HUMAN
NC score	0.120065 (rank : 183)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	183	Target Neighborhood Hits	261	Shared Neighborhood Hits	62
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

SSPO_MOUSE
NC score	0.118966 (rank : 184)	θ value	0.47712 (rank : 94)
Query Neighborhood Hits	183	Target Neighborhood Hits	800	Shared Neighborhood Hits	124
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

MT3_MOUSE
NC score	0.118119 (rank : 185)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	183	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

COMP_MOUSE
NC score	0.117308 (rank : 186)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	183	Target Neighborhood Hits	290	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TRBM_HUMAN
NC score	0.117261 (rank : 187)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	183	Target Neighborhood Hits	339	Shared Neighborhood Hits	73
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

KR171_HUMAN
NC score	0.116729 (rank : 188)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	183	Target Neighborhood Hits	144	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

LRP1_HUMAN
NC score	0.116493 (rank : 189)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	183	Target Neighborhood Hits	617	Shared Neighborhood Hits	107
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

HHIP_HUMAN
NC score	0.114746 (rank : 190)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	183	Target Neighborhood Hits	249	Shared Neighborhood Hits	67
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

C1QR1_MOUSE
NC score	0.111615 (rank : 191)	θ value	1.81305 (rank : 117)
Query Neighborhood Hits	183	Target Neighborhood Hits	342	Shared Neighborhood Hits	80
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

FBLN1_HUMAN
NC score	0.110748 (rank : 192)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	183	Target Neighborhood Hits	324	Shared Neighborhood Hits	81
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

CUBN_HUMAN
NC score	0.109924 (rank : 193)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	183	Target Neighborhood Hits	482	Shared Neighborhood Hits	91
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

KR105_HUMAN
NC score	0.109349 (rank : 194)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	183	Target Neighborhood Hits	271	Shared Neighborhood Hits	63
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

LRP1B_HUMAN
NC score	0.109276 (rank : 195)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	183	Target Neighborhood Hits	602	Shared Neighborhood Hits	102
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

COMP_HUMAN
NC score	0.108822 (rank : 196)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	183	Target Neighborhood Hits	258	Shared Neighborhood Hits	80
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NID2_HUMAN
NC score	0.108749 (rank : 197)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	183	Target Neighborhood Hits	456	Shared Neighborhood Hits	88
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

LRP1B_MOUSE
NC score	0.108217 (rank : 198)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	183	Target Neighborhood Hits	606	Shared Neighborhood Hits	105
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KR10B_HUMAN
NC score	0.108089 (rank : 199)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	183	Target Neighborhood Hits	269	Shared Neighborhood Hits	61
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

HHIP_MOUSE
NC score	0.106699 (rank : 200)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	183	Target Neighborhood Hits	219	Shared Neighborhood Hits	58
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

C1QR1_HUMAN
NC score	0.106685 (rank : 201)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	183	Target Neighborhood Hits	493	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

GAS6_HUMAN
NC score	0.106458 (rank : 202)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	183	Target Neighborhood Hits	348	Shared Neighborhood Hits	76
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

ITB2_MOUSE
NC score	0.105593 (rank : 203)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	183	Target Neighborhood Hits	326	Shared Neighborhood Hits	91
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB5_MOUSE
NC score	0.105373 (rank : 204)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	183	Target Neighborhood Hits	329	Shared Neighborhood Hits	84
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

GAS6_MOUSE
NC score	0.104844 (rank : 205)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	183	Target Neighborhood Hits	343	Shared Neighborhood Hits	77
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

KRA24_HUMAN
NC score	0.104503 (rank : 206)	θ value	0.163984 (rank : 82)
Query Neighborhood Hits	183	Target Neighborhood Hits	192	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

FBLN4_MOUSE
NC score	0.104483 (rank : 207)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	183	Target Neighborhood Hits	270	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

SLIT1_MOUSE
NC score	0.104375 (rank : 208)	θ value	0.47712 (rank : 93)
Query Neighborhood Hits	183	Target Neighborhood Hits	715	Shared Neighborhood Hits	91
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

KR102_HUMAN
NC score	0.104258 (rank : 209)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	183	Target Neighborhood Hits	264	Shared Neighborhood Hits	62
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

NID1_HUMAN
NC score	0.103781 (rank : 210)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	183	Target Neighborhood Hits	329	Shared Neighborhood Hits	79
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

PROS_MOUSE
NC score	0.103226 (rank : 211)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	183	Target Neighborhood Hits	330	Shared Neighborhood Hits	73
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

NID1_MOUSE
NC score	0.103046 (rank : 212)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	183	Target Neighborhood Hits	335	Shared Neighborhood Hits	76
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

GRN_MOUSE
NC score	0.102701 (rank : 213)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	183	Target Neighborhood Hits	248	Shared Neighborhood Hits	70
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

ITB6_MOUSE
NC score	0.102566 (rank : 214)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	183	Target Neighborhood Hits	341	Shared Neighborhood Hits	89
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

CUBN_MOUSE
NC score	0.102565 (rank : 215)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	183	Target Neighborhood Hits	477	Shared Neighborhood Hits	89
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

FBLN4_HUMAN
NC score	0.102328 (rank : 216)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	183	Target Neighborhood Hits	278	Shared Neighborhood Hits	68
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

PROS_HUMAN
NC score	0.101657 (rank : 217)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	183	Target Neighborhood Hits	340	Shared Neighborhood Hits	75
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

FBLN3_HUMAN
NC score	0.101645 (rank : 218)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	183	Target Neighborhood Hits	293	Shared Neighborhood Hits	70
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

GRN_HUMAN
NC score	0.101519 (rank : 219)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	183	Target Neighborhood Hits	268	Shared Neighborhood Hits	65
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

ITB5_HUMAN
NC score	0.101515 (rank : 220)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	183	Target Neighborhood Hits	310	Shared Neighborhood Hits	86
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

VWF_HUMAN
NC score	0.101159 (rank : 221)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	183	Target Neighborhood Hits	396	Shared Neighborhood Hits	90
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

TSP4_MOUSE
NC score	0.100638 (rank : 222)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	183	Target Neighborhood Hits	276	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

ITB3_HUMAN
NC score	0.100289 (rank : 223)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	183	Target Neighborhood Hits	325	Shared Neighborhood Hits	90
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

TSP3_MOUSE
NC score	0.099997 (rank : 224)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	183	Target Neighborhood Hits	247	Shared Neighborhood Hits	74
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

UROM_MOUSE
NC score	0.099480 (rank : 225)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	183	Target Neighborhood Hits	276	Shared Neighborhood Hits	76
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ITB1_HUMAN
NC score	0.098659 (rank : 226)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	183	Target Neighborhood Hits	298	Shared Neighborhood Hits	83
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

SLIT1_HUMAN
NC score	0.098487 (rank : 227)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	183	Target Neighborhood Hits	700	Shared Neighborhood Hits	87
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

ITB7_MOUSE
NC score	0.098007 (rank : 228)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	183	Target Neighborhood Hits	277	Shared Neighborhood Hits	75
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

UROM_HUMAN
NC score	0.097953 (rank : 229)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	183	Target Neighborhood Hits	284	Shared Neighborhood Hits	70
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

TSP4_HUMAN
NC score	0.097709 (rank : 230)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	183	Target Neighborhood Hits	277	Shared Neighborhood Hits	73
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

LRP2_HUMAN
NC score	0.097592 (rank : 231)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	183	Target Neighborhood Hits	573	Shared Neighborhood Hits	99
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ITB7_HUMAN
NC score	0.097528 (rank : 232)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	183	Target Neighborhood Hits	290	Shared Neighborhood Hits	76
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

KR109_HUMAN
NC score	0.097000 (rank : 233)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	183	Target Neighborhood Hits	226	Shared Neighborhood Hits	57
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KRA11_HUMAN
NC score	0.096789 (rank : 234)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	183	Target Neighborhood Hits	155	Shared Neighborhood Hits	38
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

EGF_MOUSE
NC score	0.096586 (rank : 235)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	183	Target Neighborhood Hits	358	Shared Neighborhood Hits	80
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

SLIT3_HUMAN
NC score	0.096343 (rank : 236)	θ value	0.163984 (rank : 83)
Query Neighborhood Hits	183	Target Neighborhood Hits	682	Shared Neighborhood Hits	85
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

TSP3_HUMAN
NC score	0.096281 (rank : 237)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	183	Target Neighborhood Hits	250	Shared Neighborhood Hits	73
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

NID2_MOUSE
NC score	0.096220 (rank : 238)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	183	Target Neighborhood Hits	338	Shared Neighborhood Hits	77
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

SLIT3_MOUSE
NC score	0.095646 (rank : 239)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	183	Target Neighborhood Hits	700	Shared Neighborhood Hits	91
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ITB2_HUMAN
NC score	0.095634 (rank : 240)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	183	Target Neighborhood Hits	282	Shared Neighborhood Hits	87
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB6_HUMAN
NC score	0.095311 (rank : 241)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	183	Target Neighborhood Hits	318	Shared Neighborhood Hits	85
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

SLIT2_HUMAN
NC score	0.094782 (rank : 242)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	183	Target Neighborhood Hits	708	Shared Neighborhood Hits	84
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ITB3_MOUSE
NC score	0.094673 (rank : 243)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	183	Target Neighborhood Hits	319	Shared Neighborhood Hits	86
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

VLDLR_HUMAN
NC score	0.094107 (rank : 244)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	183	Target Neighborhood Hits	383	Shared Neighborhood Hits	83
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

MUC5B_HUMAN
NC score	0.093533 (rank : 245)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	183	Target Neighborhood Hits	1020	Shared Neighborhood Hits	97
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

VLDLR_MOUSE
NC score	0.093482 (rank : 246)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	183	Target Neighborhood Hits	360	Shared Neighborhood Hits	79
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

LDLR_HUMAN
NC score	0.093474 (rank : 247)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	183	Target Neighborhood Hits	375	Shared Neighborhood Hits	80
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

FBLN3_MOUSE
NC score	0.093302 (rank : 248)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	183	Target Neighborhood Hits	279	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

KR108_HUMAN
NC score	0.093136 (rank : 249)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	183	Target Neighborhood Hits	226	Shared Neighborhood Hits	53
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KRA45_HUMAN
NC score	0.092761 (rank : 250)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	183	Target Neighborhood Hits	194	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

SLIT2_MOUSE
NC score	0.092761 (rank : 251)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	183	Target Neighborhood Hits	684	Shared Neighborhood Hits	79
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

KRA47_HUMAN
NC score	0.092067 (rank : 252)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	183	Target Neighborhood Hits	204	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

ITB1_MOUSE
NC score	0.091982 (rank : 253)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	183	Target Neighborhood Hits	283	Shared Neighborhood Hits	78
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ESM1_HUMAN
NC score	0.091626 (rank : 254)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	183	Target Neighborhood Hits	110	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

KRA13_HUMAN
NC score	0.090917 (rank : 255)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	183	Target Neighborhood Hits	144	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

EGFL7_HUMAN
NC score	0.090688 (rank : 256)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	183	Target Neighborhood Hits	325	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

BMPER_MOUSE
NC score	0.090575 (rank : 257)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	183	Target Neighborhood Hits	194	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

KR10C_HUMAN
NC score	0.089493 (rank : 258)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	183	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KRA94_HUMAN
NC score	0.089403 (rank : 259)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	183	Target Neighborhood Hits	204	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

NFX1_HUMAN
NC score	0.089043 (rank : 260)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	183	Target Neighborhood Hits	405	Shared Neighborhood Hits	71
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

CD248_HUMAN
NC score	0.088997 (rank : 261)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	183	Target Neighborhood Hits	679	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MATN4_MOUSE
NC score	0.088787 (rank : 262)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	183	Target Neighborhood Hits	277	Shared Neighborhood Hits	63
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

KRA98_HUMAN
NC score	0.088360 (rank : 263)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	183	Target Neighborhood Hits	185	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

EGF_HUMAN
NC score	0.088178 (rank : 264)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	183	Target Neighborhood Hits	343	Shared Neighborhood Hits	77
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

MKS3_MOUSE
NC score	0.087323 (rank : 265)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	183	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

LRP8_MOUSE
NC score	0.087046 (rank : 266)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	183	Target Neighborhood Hits	385	Shared Neighborhood Hits	76
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

KRA92_HUMAN
NC score	0.086846 (rank : 267)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	183	Target Neighborhood Hits	198	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

ITB4_HUMAN
NC score	0.086185 (rank : 268)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	183	Target Neighborhood Hits	458	Shared Neighborhood Hits	90
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

CD248_MOUSE
NC score	0.086180 (rank : 269)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	183	Target Neighborhood Hits	578	Shared Neighborhood Hits	60
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

KRA93_HUMAN
NC score	0.086088 (rank : 270)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	183	Target Neighborhood Hits	203	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KR10A_HUMAN
NC score	0.085524 (rank : 271)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	183	Target Neighborhood Hits	232	Shared Neighborhood Hits	62
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

VWF_MOUSE
NC score	0.084342 (rank : 272)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	183	Target Neighborhood Hits	381	Shared Neighborhood Hits	89
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KR410_HUMAN
NC score	0.083653 (rank : 273)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	183	Target Neighborhood Hits	156	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

MATN3_HUMAN
NC score	0.083523 (rank : 274)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	183	Target Neighborhood Hits	268	Shared Neighborhood Hits	55
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
NC score	0.083402 (rank : 275)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	183	Target Neighborhood Hits	287	Shared Neighborhood Hits	64
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

ESM1_MOUSE
NC score	0.083180 (rank : 276)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	183	Target Neighborhood Hits	107	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

KR103_HUMAN
NC score	0.082882 (rank : 277)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	183	Target Neighborhood Hits	212	Shared Neighborhood Hits	51
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

LDLR_MOUSE
NC score	0.082875 (rank : 278)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	183	Target Neighborhood Hits	382	Shared Neighborhood Hits	77
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

EGFL7_MOUSE
NC score	0.082714 (rank : 279)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	183	Target Neighborhood Hits	287	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

MATN3_MOUSE
NC score	0.081314 (rank : 280)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	183	Target Neighborhood Hits	261	Shared Neighborhood Hits	57
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

BMPER_HUMAN
NC score	0.081278 (rank : 281)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	183	Target Neighborhood Hits	175	Shared Neighborhood Hits	45
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

TENR_MOUSE
NC score	0.080508 (rank : 282)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	183	Target Neighborhood Hits	531	Shared Neighborhood Hits	96
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENR_HUMAN
NC score	0.080370 (rank : 283)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	183	Target Neighborhood Hits	526	Shared Neighborhood Hits	96
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

RSPO4_HUMAN
NC score	0.079958 (rank : 284)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	183	Target Neighborhood Hits	110	Shared Neighborhood Hits	35
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

KR414_HUMAN
NC score	0.079952 (rank : 285)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	183	Target Neighborhood Hits	199	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

EMR1_HUMAN
NC score	0.079860 (rank : 286)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	183	Target Neighborhood Hits	382	Shared Neighborhood Hits	75
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EGFL8_HUMAN
NC score	0.078897 (rank : 287)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	183	Target Neighborhood Hits	270	Shared Neighborhood Hits	55
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

KRA15_HUMAN
NC score	0.078636 (rank : 288)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	183	Target Neighborhood Hits	126	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

NRX1A_HUMAN
NC score	0.078264 (rank : 289)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	183	Target Neighborhood Hits	170	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

MUC13_MOUSE
NC score	0.078182 (rank : 290)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	183	Target Neighborhood Hits	447	Shared Neighborhood Hits	58
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SORL_MOUSE
NC score	0.078077 (rank : 291)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	183	Target Neighborhood Hits	439	Shared Neighborhood Hits	81
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

EDIL3_MOUSE
NC score	0.077843 (rank : 292)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	183	Target Neighborhood Hits	317	Shared Neighborhood Hits	64
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

ITB8_HUMAN
NC score	0.077755 (rank : 293)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	183	Target Neighborhood Hits	280	Shared Neighborhood Hits	75
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

NRX1A_MOUSE
NC score	0.077521 (rank : 294)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	183	Target Neighborhood Hits	164	Shared Neighborhood Hits	32
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX3A_HUMAN
NC score	0.077272 (rank : 295)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	183	Target Neighborhood Hits	164	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

KR412_HUMAN
NC score	0.076957 (rank : 296)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	183	Target Neighborhood Hits	178	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

LRP8_HUMAN
NC score	0.076716 (rank : 297)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	183	Target Neighborhood Hits	346	Shared Neighborhood Hits	69
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MT1X_HUMAN
NC score	0.076710 (rank : 298)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	183	Target Neighborhood Hits	76	Shared Neighborhood Hits	31
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

RSPO4_MOUSE
NC score	0.076628 (rank : 299)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	183	Target Neighborhood Hits	110	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

CELR2_HUMAN
NC score	0.076232 (rank : 300)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	183	Target Neighborhood Hits	657	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

EMR2_HUMAN
NC score	0.076200 (rank : 301)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	183	Target Neighborhood Hits	345	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

TSP1_MOUSE
NC score	0.075699 (rank : 302)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	183	Target Neighborhood Hits	396	Shared Neighborhood Hits	83
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

LRP4_MOUSE
NC score	0.075414 (rank : 303)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	183	Target Neighborhood Hits	351	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

CD97_HUMAN
NC score	0.075398 (rank : 304)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	183	Target Neighborhood Hits	353	Shared Neighborhood Hits	68
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

SUSD1_HUMAN
NC score	0.075171 (rank : 305)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	183	Target Neighborhood Hits	285	Shared Neighborhood Hits	47
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

LRP4_HUMAN
NC score	0.075106 (rank : 306)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	183	Target Neighborhood Hits	355	Shared Neighborhood Hits	74
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

CELR3_MOUSE
NC score	0.074795 (rank : 307)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	183	Target Neighborhood Hits	687	Shared Neighborhood Hits	93
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR1_MOUSE
NC score	0.074139 (rank : 308)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	183	Target Neighborhood Hits	617	Shared Neighborhood Hits	87
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

KRA44_HUMAN
NC score	0.073557 (rank : 309)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	183	Target Neighborhood Hits	162	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

SORL_HUMAN
NC score	0.073508 (rank : 310)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	183	Target Neighborhood Hits	440	Shared Neighborhood Hits	74
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

CELR3_HUMAN
NC score	0.073496 (rank : 311)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	183	Target Neighborhood Hits	680	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

EDIL3_HUMAN
NC score	0.073363 (rank : 312)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	183	Target Neighborhood Hits	292	Shared Neighborhood Hits	66
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL8_MOUSE
NC score	0.073312 (rank : 313)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	183	Target Neighborhood Hits	266	Shared Neighborhood Hits	51
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

TSP1_HUMAN
NC score	0.073010 (rank : 314)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	183	Target Neighborhood Hits	389	Shared Neighborhood Hits	81
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

CELR1_HUMAN
NC score	0.072469 (rank : 315)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	183	Target Neighborhood Hits	613	Shared Neighborhood Hits	84
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

MT3_HUMAN
NC score	0.072423 (rank : 316)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	183	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

ODFP_MOUSE
NC score	0.071269 (rank : 317)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	183	Target Neighborhood Hits	75	Shared Neighborhood Hits	24
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

ZAN_HUMAN
NC score	0.070989 (rank : 318)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	183	Target Neighborhood Hits	679	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

LCE1C_HUMAN
NC score	0.070691 (rank : 319)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	183	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

CELR2_MOUSE
NC score	0.070611 (rank : 320)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	183	Target Neighborhood Hits	584	Shared Neighborhood Hits	77
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

KRA99_HUMAN
NC score	0.070211 (rank : 321)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	183	Target Neighborhood Hits	173	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

NRX2A_HUMAN
NC score	0.069999 (rank : 322)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	183	Target Neighborhood Hits	614	Shared Neighborhood Hits	40
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

SHBG_HUMAN
NC score	0.069917 (rank : 323)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	183	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

EMR1_MOUSE
NC score	0.069206 (rank : 324)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	183	Target Neighborhood Hits	349	Shared Neighborhood Hits	60
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

RSPO1_HUMAN
NC score	0.069157 (rank : 325)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	183	Target Neighborhood Hits	101	Shared Neighborhood Hits	32
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

LCE1B_HUMAN
NC score	0.068051 (rank : 326)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	183	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

MKS3_HUMAN
NC score	0.067099 (rank : 327)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	183	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

THOC1_MOUSE
NC score	0.066671 (rank : 328)	θ value	0.125558 (rank : 79)
Query Neighborhood Hits	183	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R3N6, Q8BWD5, Q8BXY3	Gene names	Thoc1
Domain Architecture
Description	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84).

HMCN1_HUMAN
NC score	0.066269 (rank : 329)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	183	Target Neighborhood Hits	983	Shared Neighborhood Hits	79
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

TENN_HUMAN
NC score	0.066015 (rank : 330)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	183	Target Neighborhood Hits	453	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TSP2_MOUSE
NC score	0.065168 (rank : 331)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	183	Target Neighborhood Hits	352	Shared Neighborhood Hits	76
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

SHBG_MOUSE
NC score	0.064263 (rank : 332)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	183	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

FATH_HUMAN
NC score	0.063817 (rank : 333)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	183	Target Neighborhood Hits	570	Shared Neighborhood Hits	79
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

KRA42_HUMAN
NC score	0.063427 (rank : 334)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	183	Target Neighborhood Hits	149	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

CNBP_HUMAN
NC score	0.063249 (rank : 335)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	183	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	P62633, P20694, Q5QJR0, Q6PJI7, Q96NV3	Gene names	CNBP, ZNF9
Domain Architecture	No domain graphic available
Description	Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9).

MT1A_HUMAN
NC score	0.063219 (rank : 336)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	183	Target Neighborhood Hits	74	Shared Neighborhood Hits	21
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

TENN_MOUSE
NC score	0.062872 (rank : 337)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	183	Target Neighborhood Hits	484	Shared Neighborhood Hits	89
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

LYAM3_MOUSE
NC score	0.062569 (rank : 338)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	183	Target Neighborhood Hits	390	Shared Neighborhood Hits	66
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

RSPO3_HUMAN
NC score	0.062558 (rank : 339)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	183	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

MUC2_HUMAN
NC score	0.062521 (rank : 340)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	183	Target Neighborhood Hits	906	Shared Neighborhood Hits	75
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MT2_MOUSE
NC score	0.062460 (rank : 341)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	183	Target Neighborhood Hits	81	Shared Neighborhood Hits	22
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

LYAM3_HUMAN
NC score	0.061997 (rank : 342)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	183	Target Neighborhood Hits	378	Shared Neighborhood Hits	69
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CNTP2_MOUSE
NC score	0.061663 (rank : 343)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	183	Target Neighborhood Hits	194	Shared Neighborhood Hits	38
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

FURIN_HUMAN
NC score	0.061595 (rank : 344)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	183	Target Neighborhood Hits	52	Shared Neighborhood Hits	11
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

MT1_MOUSE
NC score	0.061125 (rank : 345)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	183	Target Neighborhood Hits	72	Shared Neighborhood Hits	18
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

TSP2_HUMAN
NC score	0.060765 (rank : 346)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	183	Target Neighborhood Hits	359	Shared Neighborhood Hits	74
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

CNTP2_HUMAN
NC score	0.060738 (rank : 347)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	183	Target Neighborhood Hits	199	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

LYAM2_MOUSE
NC score	0.060738 (rank : 348)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	183	Target Neighborhood Hits	420	Shared Neighborhood Hits	70
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

RSPO3_MOUSE
NC score	0.059721 (rank : 349)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	183	Target Neighborhood Hits	120	Shared Neighborhood Hits	35
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

MT1B_HUMAN
NC score	0.059431 (rank : 350)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	183	Target Neighborhood Hits	87	Shared Neighborhood Hits	27
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

CSPG2_MOUSE
NC score	0.058388 (rank : 351)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	183	Target Neighborhood Hits	711	Shared Neighborhood Hits	75
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

TECTA_MOUSE
NC score	0.058161 (rank : 352)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	183	Target Neighborhood Hits	244	Shared Neighborhood Hits	56
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

PROZ_MOUSE
NC score	0.057717 (rank : 353)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	183	Target Neighborhood Hits	410	Shared Neighborhood Hits	55
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

LCE2A_HUMAN
NC score	0.057427 (rank : 354)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	183	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

CNTP4_HUMAN
NC score	0.057034 (rank : 355)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	183	Target Neighborhood Hits	187	Shared Neighborhood Hits	32
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CSPG3_MOUSE
NC score	0.056974 (rank : 356)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	183	Target Neighborhood Hits	657	Shared Neighborhood Hits	74
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

PROZ_HUMAN
NC score	0.056375 (rank : 357)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	183	Target Neighborhood Hits	422	Shared Neighborhood Hits	60
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

LCE2C_HUMAN
NC score	0.056364 (rank : 358)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	183	Target Neighborhood Hits	53	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2B_HUMAN
NC score	0.055995 (rank : 359)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	183	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

FURIN_MOUSE
NC score	0.055527 (rank : 360)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	183	Target Neighborhood Hits	49	Shared Neighborhood Hits	10
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

CSPG2_HUMAN
NC score	0.055500 (rank : 361)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	183	Target Neighborhood Hits	681	Shared Neighborhood Hits	72
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CT127_HUMAN
NC score	0.055403 (rank : 362)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	183	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

CHRD_MOUSE
NC score	0.055291 (rank : 363)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	183	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

MT4_MOUSE
NC score	0.055282 (rank : 364)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	183	Target Neighborhood Hits	102	Shared Neighborhood Hits	28
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

LYAM2_HUMAN
NC score	0.055158 (rank : 365)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	183	Target Neighborhood Hits	394	Shared Neighborhood Hits	68
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CSPG3_HUMAN
NC score	0.055049 (rank : 366)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	183	Target Neighborhood Hits	676	Shared Neighborhood Hits	70
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CHRD_HUMAN
NC score	0.054968 (rank : 367)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	183	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

THOC1_HUMAN
NC score	0.054738 (rank : 368)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	183	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q96FV9, Q15219	Gene names	THOC1, HPR1
Domain Architecture
Description	THO complex subunit 1 (Tho1) (Nuclear matrix protein p84).

CNTP4_MOUSE
NC score	0.054435 (rank : 369)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	183	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

RSPO2_MOUSE
NC score	0.054397 (rank : 370)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	183	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

CD97_MOUSE
NC score	0.054204 (rank : 371)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	183	Target Neighborhood Hits	295	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

RSPO2_HUMAN
NC score	0.054135 (rank : 372)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	183	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

MT1H_HUMAN
NC score	0.053326 (rank : 373)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	183	Target Neighborhood Hits	78	Shared Neighborhood Hits	24
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

LCE2D_HUMAN
NC score	0.052634 (rank : 374)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	183	Target Neighborhood Hits	50	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

CSPG4_HUMAN
NC score	0.052394 (rank : 375)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	183	Target Neighborhood Hits	112	Shared Neighborhood Hits	18
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

LCE3B_HUMAN
NC score	0.052289 (rank : 376)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	183	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

TIE1_HUMAN
NC score	0.052232 (rank : 377)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	183	Target Neighborhood Hits	1241	Shared Neighborhood Hits	96
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

THYG_MOUSE
NC score	0.051787 (rank : 378)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	183	Target Neighborhood Hits	161	Shared Neighborhood Hits	50
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TDGF1_MOUSE
NC score	0.051400 (rank : 379)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	183	Target Neighborhood Hits	146	Shared Neighborhood Hits	38
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

PCSK4_HUMAN
NC score	0.051268 (rank : 380)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	183	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

LCE1F_HUMAN
NC score	0.050885 (rank : 381)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	183	Target Neighborhood Hits	48	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

MLL3_MOUSE
NC score	0.050149 (rank : 382)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	183	Target Neighborhood Hits	1399	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL2_HUMAN
NC score	0.049017 (rank : 383)	θ value	0.0961366 (rank : 77)
Query Neighborhood Hits	183	Target Neighborhood Hits	1788	Shared Neighborhood Hits	40
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

THYG_HUMAN
NC score	0.048441 (rank : 384)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	183	Target Neighborhood Hits	154	Shared Neighborhood Hits	48
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

MLL3_HUMAN
NC score	0.047574 (rank : 385)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	183	Target Neighborhood Hits	1644	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

LRP3_HUMAN
NC score	0.044862 (rank : 386)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	183	Target Neighborhood Hits	280	Shared Neighborhood Hits	40
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

ADA11_HUMAN
NC score	0.044189 (rank : 387)	θ value	5.27518 (rank : 149)
Query Neighborhood Hits	183	Target Neighborhood Hits	259	Shared Neighborhood Hits	64
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
NC score	0.044025 (rank : 388)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	183	Target Neighborhood Hits	263	Shared Neighborhood Hits	64
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA23_HUMAN
NC score	0.041484 (rank : 389)	θ value	1.38821 (rank : 111)
Query Neighborhood Hits	183	Target Neighborhood Hits	235	Shared Neighborhood Hits	57
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
NC score	0.040525 (rank : 390)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	183	Target Neighborhood Hits	245	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

EPHB6_MOUSE
NC score	0.032766 (rank : 391)	θ value	0.0736092 (rank : 73)
Query Neighborhood Hits	183	Target Neighborhood Hits	906	Shared Neighborhood Hits	54
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHB6_HUMAN
NC score	0.032027 (rank : 392)	θ value	1.38821 (rank : 112)
Query Neighborhood Hits	183	Target Neighborhood Hits	912	Shared Neighborhood Hits	59
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

TRI56_MOUSE
NC score	0.029107 (rank : 393)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	183	Target Neighborhood Hits	255	Shared Neighborhood Hits	12
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

EPHA7_HUMAN
NC score	0.028582 (rank : 394)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	183	Target Neighborhood Hits	1053	Shared Neighborhood Hits	68
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA6_HUMAN
NC score	0.027013 (rank : 395)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	183	Target Neighborhood Hits	959	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA6_MOUSE
NC score	0.026947 (rank : 396)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	183	Target Neighborhood Hits	946	Shared Neighborhood Hits	44
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

ANK3_HUMAN
NC score	0.022766 (rank : 397)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	183	Target Neighborhood Hits	853	Shared Neighborhood Hits	22
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

EPHA7_MOUSE
NC score	0.022638 (rank : 398)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	183	Target Neighborhood Hits	1025	Shared Neighborhood Hits	59
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHB1_HUMAN
NC score	0.020712 (rank : 399)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	183	Target Neighborhood Hits	988	Shared Neighborhood Hits	57
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

SORC2_HUMAN
NC score	0.019329 (rank : 400)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	183	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q96PQ0, Q9P2L7	Gene names	SORCS2, KIAA1329
Domain Architecture
Description	VPS10 domain-containing receptor SorCS2 precursor.

EPHB2_HUMAN
NC score	0.018456 (rank : 401)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	183	Target Neighborhood Hits	983	Shared Neighborhood Hits	43
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
NC score	0.018453 (rank : 402)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	183	Target Neighborhood Hits	982	Shared Neighborhood Hits	43
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

IBP7_MOUSE
NC score	0.017735 (rank : 403)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	183	Target Neighborhood Hits	230	Shared Neighborhood Hits	13
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

TRI56_HUMAN
NC score	0.017176 (rank : 404)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	183	Target Neighborhood Hits	339	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

DPOE1_MOUSE
NC score	0.015666 (rank : 405)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	183	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

TOIP2_HUMAN
NC score	0.015057 (rank : 406)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	183	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFQ8	Gene names	TOR1AIP2, LULL1
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2 (Lumenal domain-like LAP1).

SDC3_MOUSE
NC score	0.014729 (rank : 407)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	183	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

ROBO3_HUMAN
NC score	0.014290 (rank : 408)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	183	Target Neighborhood Hits	570	Shared Neighborhood Hits	19
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

TIF1A_HUMAN
NC score	0.014213 (rank : 409)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	183	Target Neighborhood Hits	327	Shared Neighborhood Hits	11
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

CHD4_HUMAN
NC score	0.014150 (rank : 410)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	183	Target Neighborhood Hits	365	Shared Neighborhood Hits	9
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

MYCB2_HUMAN
NC score	0.013123 (rank : 411)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	183	Target Neighborhood Hits	390	Shared Neighborhood Hits	16
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MIB2_HUMAN
NC score	0.012711 (rank : 412)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	183	Target Neighborhood Hits	438	Shared Neighborhood Hits	9
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

CHD4_MOUSE
NC score	0.012467 (rank : 413)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	183	Target Neighborhood Hits	408	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

RIPK1_MOUSE
NC score	0.010923 (rank : 414)	θ value	0.813845 (rank : 106)
Query Neighborhood Hits	183	Target Neighborhood Hits	874	Shared Neighborhood Hits	23
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_HUMAN
NC score	0.010904 (rank : 415)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	183	Target Neighborhood Hits	891	Shared Neighborhood Hits	25
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

AP180_MOUSE
NC score	0.010239 (rank : 416)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	183	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

HNF1A_MOUSE
NC score	0.009213 (rank : 417)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	183	Target Neighborhood Hits	212	Shared Neighborhood Hits	9
SwissProt Accessions	P22361	Gene names	Tcf1, Hnf-1, Hnf-1a, Hnf1a
Domain Architecture
Description	Hepatocyte nuclear factor 1-alpha (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1).

MIB2_MOUSE
NC score	0.008895 (rank : 418)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	183	Target Neighborhood Hits	409	Shared Neighborhood Hits	8
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

CASR_HUMAN
NC score	0.007711 (rank : 419)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	183	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CEP35_HUMAN
NC score	0.007402 (rank : 420)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	183	Target Neighborhood Hits	811	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

TTBK2_HUMAN
NC score	0.006592 (rank : 421)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	183	Target Neighborhood Hits	822	Shared Neighborhood Hits	16
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

LIRB3_HUMAN
NC score	0.006102 (rank : 422)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	183	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	O75022, O15471, Q86U49	Gene names	LILRB3, ILT5, LIR3
Domain Architecture	No domain graphic available
Description	Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor (Leukocyte immunoglobulin-like receptor 3) (LIR-3) (Immunoglobulin- like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD85a antigen).

NMD3B_HUMAN
NC score	0.005794 (rank : 423)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	183	Target Neighborhood Hits	55	Shared Neighborhood Hits	3
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

DAPK1_MOUSE
NC score	0.002796 (rank : 424)	θ value	4.03905 (rank : 139)
Query Neighborhood Hits	183	Target Neighborhood Hits	1138	Shared Neighborhood Hits	20
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_HUMAN
NC score	0.002485 (rank : 425)	θ value	1.81305 (rank : 118)
Query Neighborhood Hits	183	Target Neighborhood Hits	1130	Shared Neighborhood Hits	19
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

HXA10_MOUSE
NC score	-0.001415 (rank : 426)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	183	Target Neighborhood Hits	365	Shared Neighborhood Hits	2
SwissProt Accessions	P31310, Q80Y22	Gene names	Hoxa10, Hox-1.8, Hoxa-10
Domain Architecture
Description	Homeobox protein Hox-A10 (Hox-1.8).

ZFP13_MOUSE
NC score	-0.003685 (rank : 427)	θ value	0.62314 (rank : 100)
Query Neighborhood Hits	183	Target Neighborhood Hits	771	Shared Neighborhood Hits	6
SwissProt Accessions	P10754, Q80WS0, Q8CDD0	Gene names	Zfp13, Krox-8, Zfp-13
Domain Architecture	No domain graphic available
Description	Zinc finger protein 13 (Zfp-13) (Krox-8 protein).