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Network neighborhood for query Sequence : THYG_HUMAN

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THYG_HUMAN
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

THYG_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	154	Target Neighborhood Hits	154	Shared Neighborhood Hits	154
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

THYG_MOUSE
θ value	0 (rank : 2)	NC score	0.990719 (rank : 2)
Query Neighborhood Hits	154	Target Neighborhood Hits	161	Shared Neighborhood Hits	106
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

ACES_HUMAN
θ value	4.53632e-60 (rank : 3)	NC score	0.832330 (rank : 3)
Query Neighborhood Hits	154	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

CHLE_MOUSE
θ value	2.48917e-58 (rank : 4)	NC score	0.831303 (rank : 5)
Query Neighborhood Hits	154	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

ACES_MOUSE
θ value	2.32979e-56 (rank : 5)	NC score	0.831553 (rank : 4)
Query Neighborhood Hits	154	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

CHLE_HUMAN
θ value	1.08223e-53 (rank : 6)	NC score	0.828352 (rank : 6)
Query Neighborhood Hits	154	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

EST2_HUMAN
θ value	3.48949e-44 (rank : 7)	NC score	0.815758 (rank : 7)
Query Neighborhood Hits	154	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

NLGN3_MOUSE
θ value	3.85808e-43 (rank : 8)	NC score	0.791138 (rank : 17)
Query Neighborhood Hits	154	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGNX_HUMAN
θ value	5.03882e-43 (rank : 9)	NC score	0.790827 (rank : 19)
Query Neighborhood Hits	154	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGNY_HUMAN
θ value	5.03882e-43 (rank : 10)	NC score	0.791087 (rank : 18)
Query Neighborhood Hits	154	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

NLGN2_HUMAN
θ value	2.50074e-42 (rank : 11)	NC score	0.793576 (rank : 15)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
θ value	7.27602e-42 (rank : 12)	NC score	0.793139 (rank : 16)
Query Neighborhood Hits	154	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN3_HUMAN
θ value	3.61106e-41 (rank : 13)	NC score	0.789427 (rank : 20)
Query Neighborhood Hits	154	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

EST31_MOUSE
θ value	6.15952e-41 (rank : 14)	NC score	0.809986 (rank : 9)
Query Neighborhood Hits	154	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

EST1_MOUSE
θ value	3.37985e-39 (rank : 15)	NC score	0.796199 (rank : 13)
Query Neighborhood Hits	154	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

CEL_MOUSE
θ value	4.41421e-39 (rank : 16)	NC score	0.813388 (rank : 8)
Query Neighborhood Hits	154	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CES3_MOUSE
θ value	7.52953e-39 (rank : 17)	NC score	0.798023 (rank : 11)
Query Neighborhood Hits	154	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

NLGN1_HUMAN
θ value	1.28434e-38 (rank : 18)	NC score	0.785152 (rank : 22)
Query Neighborhood Hits	154	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

CEL_HUMAN
θ value	2.19075e-38 (rank : 19)	NC score	0.614022 (rank : 23)
Query Neighborhood Hits	154	Target Neighborhood Hits	896	Shared Neighborhood Hits	30
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

NLGN1_MOUSE
θ value	3.73686e-38 (rank : 20)	NC score	0.785310 (rank : 21)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

EST22_MOUSE
θ value	1.85459e-37 (rank : 21)	NC score	0.798456 (rank : 10)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

EST1_HUMAN
θ value	7.04741e-37 (rank : 22)	NC score	0.796092 (rank : 14)
Query Neighborhood Hits	154	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

ESTN_MOUSE
θ value	2.26708e-35 (rank : 23)	NC score	0.796597 (rank : 12)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

NID2_HUMAN
θ value	3.07829e-16 (rank : 24)	NC score	0.203295 (rank : 47)
Query Neighborhood Hits	154	Target Neighborhood Hits	456	Shared Neighborhood Hits	75
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
θ value	4.02038e-16 (rank : 25)	NC score	0.201121 (rank : 48)
Query Neighborhood Hits	154	Target Neighborhood Hits	338	Shared Neighborhood Hits	71
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

SMOC2_HUMAN
θ value	1.99529e-15 (rank : 26)	NC score	0.368028 (rank : 25)
Query Neighborhood Hits	154	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC2_MOUSE
θ value	2.60593e-15 (rank : 27)	NC score	0.369060 (rank : 24)
Query Neighborhood Hits	154	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC1_HUMAN
θ value	1.86753e-13 (rank : 28)	NC score	0.354841 (rank : 26)
Query Neighborhood Hits	154	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
θ value	2.0648e-12 (rank : 29)	NC score	0.347707 (rank : 27)
Query Neighborhood Hits	154	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

NID1_MOUSE
θ value	1.38499e-08 (rank : 30)	NC score	0.173235 (rank : 53)
Query Neighborhood Hits	154	Target Neighborhood Hits	335	Shared Neighborhood Hits	69
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SCUB3_HUMAN
θ value	1.38499e-08 (rank : 31)	NC score	0.110537 (rank : 55)
Query Neighborhood Hits	154	Target Neighborhood Hits	428	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	1.38499e-08 (rank : 32)	NC score	0.110285 (rank : 56)
Query Neighborhood Hits	154	Target Neighborhood Hits	442	Shared Neighborhood Hits	74
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NID1_HUMAN
θ value	3.08544e-08 (rank : 33)	NC score	0.176065 (rank : 52)
Query Neighborhood Hits	154	Target Neighborhood Hits	329	Shared Neighborhood Hits	71
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TICN3_HUMAN
θ value	5.81887e-07 (rank : 34)	NC score	0.273965 (rank : 34)
Query Neighborhood Hits	154	Target Neighborhood Hits	82	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_MOUSE
θ value	9.92553e-07 (rank : 35)	NC score	0.270708 (rank : 35)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN1_HUMAN
θ value	1.29631e-06 (rank : 36)	NC score	0.279471 (rank : 30)
Query Neighborhood Hits	154	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_MOUSE
θ value	1.29631e-06 (rank : 37)	NC score	0.278488 (rank : 32)
Query Neighborhood Hits	154	Target Neighborhood Hits	79	Shared Neighborhood Hits	34
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN2_HUMAN
θ value	1.69304e-06 (rank : 38)	NC score	0.278863 (rank : 31)
Query Neighborhood Hits	154	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_MOUSE
θ value	2.21117e-06 (rank : 39)	NC score	0.277046 (rank : 33)
Query Neighborhood Hits	154	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

IBP6_HUMAN
θ value	6.43352e-06 (rank : 40)	NC score	0.261056 (rank : 36)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

HG2A_MOUSE
θ value	1.43324e-05 (rank : 41)	NC score	0.308268 (rank : 28)
Query Neighborhood Hits	154	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

HG2A_HUMAN
θ value	9.29e-05 (rank : 42)	NC score	0.293543 (rank : 29)
Query Neighborhood Hits	154	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

IBP1_HUMAN
θ value	0.000158464 (rank : 43)	NC score	0.239089 (rank : 37)
Query Neighborhood Hits	154	Target Neighborhood Hits	67	Shared Neighborhood Hits	36
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP1_MOUSE
θ value	0.000158464 (rank : 44)	NC score	0.227822 (rank : 40)
Query Neighborhood Hits	154	Target Neighborhood Hits	97	Shared Neighborhood Hits	36
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP5_HUMAN
θ value	0.00102713 (rank : 45)	NC score	0.217037 (rank : 44)
Query Neighborhood Hits	154	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP4_HUMAN
θ value	0.00228821 (rank : 46)	NC score	0.220118 (rank : 42)
Query Neighborhood Hits	154	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
θ value	0.00228821 (rank : 47)	NC score	0.221341 (rank : 41)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP5_MOUSE
θ value	0.00228821 (rank : 48)	NC score	0.216809 (rank : 45)
Query Neighborhood Hits	154	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP3_HUMAN
θ value	0.00390308 (rank : 49)	NC score	0.228967 (rank : 39)
Query Neighborhood Hits	154	Target Neighborhood Hits	67	Shared Neighborhood Hits	34
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP6_MOUSE
θ value	0.00509761 (rank : 50)	NC score	0.231581 (rank : 38)
Query Neighborhood Hits	154	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

LAMA5_HUMAN
θ value	0.00509761 (rank : 51)	NC score	0.064014 (rank : 71)
Query Neighborhood Hits	154	Target Neighborhood Hits	976	Shared Neighborhood Hits	78
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMC2_HUMAN
θ value	0.00509761 (rank : 52)	NC score	0.071417 (rank : 64)
Query Neighborhood Hits	154	Target Neighborhood Hits	715	Shared Neighborhood Hits	74
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	0.00509761 (rank : 53)	NC score	0.076600 (rank : 60)
Query Neighborhood Hits	154	Target Neighborhood Hits	614	Shared Neighborhood Hits	76
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

IBP2_MOUSE
θ value	0.0113563 (rank : 54)	NC score	0.205324 (rank : 46)
Query Neighborhood Hits	154	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

MEGF9_HUMAN
θ value	0.0148317 (rank : 55)	NC score	0.086224 (rank : 58)
Query Neighborhood Hits	154	Target Neighborhood Hits	557	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

EPHB3_HUMAN
θ value	0.0193708 (rank : 56)	NC score	0.044059 (rank : 138)
Query Neighborhood Hits	154	Target Neighborhood Hits	996	Shared Neighborhood Hits	56
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

IBP3_MOUSE
θ value	0.0193708 (rank : 57)	NC score	0.217543 (rank : 43)
Query Neighborhood Hits	154	Target Neighborhood Hits	60	Shared Neighborhood Hits	35
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP2_HUMAN
θ value	0.0252991 (rank : 58)	NC score	0.194486 (rank : 49)
Query Neighborhood Hits	154	Target Neighborhood Hits	61	Shared Neighborhood Hits	33
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

FBLN1_HUMAN
θ value	0.0563607 (rank : 59)	NC score	0.063173 (rank : 73)
Query Neighborhood Hits	154	Target Neighborhood Hits	324	Shared Neighborhood Hits	49
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

MEGF9_MOUSE
θ value	0.0563607 (rank : 60)	NC score	0.074512 (rank : 63)
Query Neighborhood Hits	154	Target Neighborhood Hits	896	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

EPHB4_HUMAN
θ value	0.0736092 (rank : 61)	NC score	0.042970 (rank : 140)
Query Neighborhood Hits	154	Target Neighborhood Hits	1056	Shared Neighborhood Hits	62
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

EPHB4_MOUSE
θ value	0.0736092 (rank : 62)	NC score	0.040446 (rank : 149)
Query Neighborhood Hits	154	Target Neighborhood Hits	1013	Shared Neighborhood Hits	55
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

MEGF6_HUMAN
θ value	0.0736092 (rank : 63)	NC score	0.070377 (rank : 65)
Query Neighborhood Hits	154	Target Neighborhood Hits	671	Shared Neighborhood Hits	79
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TACD1_HUMAN
θ value	0.0736092 (rank : 64)	NC score	0.187139 (rank : 50)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	33
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

TENR_HUMAN
θ value	0.0736092 (rank : 65)	NC score	0.037019 (rank : 158)
Query Neighborhood Hits	154	Target Neighborhood Hits	526	Shared Neighborhood Hits	66
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

EPHB2_HUMAN
θ value	0.125558 (rank : 66)	NC score	0.040001 (rank : 152)
Query Neighborhood Hits	154	Target Neighborhood Hits	983	Shared Neighborhood Hits	46
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.125558 (rank : 67)	NC score	0.040006 (rank : 151)
Query Neighborhood Hits	154	Target Neighborhood Hits	982	Shared Neighborhood Hits	46
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

TENR_MOUSE
θ value	0.125558 (rank : 68)	NC score	0.036275 (rank : 160)
Query Neighborhood Hits	154	Target Neighborhood Hits	531	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

EPHA4_MOUSE
θ value	0.163984 (rank : 69)	NC score	0.038611 (rank : 154)
Query Neighborhood Hits	154	Target Neighborhood Hits	982	Shared Neighborhood Hits	48
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHB3_MOUSE
θ value	0.163984 (rank : 70)	NC score	0.042087 (rank : 144)
Query Neighborhood Hits	154	Target Neighborhood Hits	996	Shared Neighborhood Hits	50
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

LAMA1_MOUSE
θ value	0.163984 (rank : 71)	NC score	0.059668 (rank : 79)
Query Neighborhood Hits	154	Target Neighborhood Hits	838	Shared Neighborhood Hits	76
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

EPHA7_HUMAN
θ value	0.21417 (rank : 72)	NC score	0.041147 (rank : 147)
Query Neighborhood Hits	154	Target Neighborhood Hits	1053	Shared Neighborhood Hits	66
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

MUC5B_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.034625 (rank : 163)
Query Neighborhood Hits	154	Target Neighborhood Hits	1020	Shared Neighborhood Hits	46
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NOTC3_HUMAN
θ value	0.21417 (rank : 74)	NC score	0.050120 (rank : 128)
Query Neighborhood Hits	154	Target Neighborhood Hits	1062	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

RPB2_HUMAN
θ value	0.21417 (rank : 75)	NC score	0.030538 (rank : 171)
Query Neighborhood Hits	154	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P30876, Q8IZ61	Gene names	POLR2B
Domain Architecture
Description	DNA-directed RNA polymerase II 140 kDa polypeptide (EC 2.7.7.6) (RNA polymerase II subunit 2) (RPB2).

RPB2_MOUSE
θ value	0.21417 (rank : 76)	NC score	0.030532 (rank : 172)
Query Neighborhood Hits	154	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFI7	Gene names	Polr2b
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase II 140 kDa polypeptide (EC 2.7.7.6) (RNA polymerase II subunit 2) (RPB2).

EPHA8_HUMAN
θ value	0.279714 (rank : 77)	NC score	0.034881 (rank : 162)
Query Neighborhood Hits	154	Target Neighborhood Hits	956	Shared Neighborhood Hits	39
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHB6_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.049562 (rank : 131)
Query Neighborhood Hits	154	Target Neighborhood Hits	912	Shared Neighborhood Hits	54
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

LAMA3_MOUSE
θ value	0.279714 (rank : 79)	NC score	0.057375 (rank : 83)
Query Neighborhood Hits	154	Target Neighborhood Hits	859	Shared Neighborhood Hits	68
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

PCSK5_MOUSE
θ value	0.279714 (rank : 80)	NC score	0.054885 (rank : 95)
Query Neighborhood Hits	154	Target Neighborhood Hits	613	Shared Neighborhood Hits	70
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

EPHA2_MOUSE
θ value	0.365318 (rank : 81)	NC score	0.038655 (rank : 153)
Query Neighborhood Hits	154	Target Neighborhood Hits	1020	Shared Neighborhood Hits	59
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHA1_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.037308 (rank : 156)
Query Neighborhood Hits	154	Target Neighborhood Hits	997	Shared Neighborhood Hits	54
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHB6_MOUSE
θ value	0.62314 (rank : 83)	NC score	0.046909 (rank : 135)
Query Neighborhood Hits	154	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

FBLN1_MOUSE
θ value	0.62314 (rank : 84)	NC score	0.063709 (rank : 72)
Query Neighborhood Hits	154	Target Neighborhood Hits	329	Shared Neighborhood Hits	52
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

LYAM3_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.026878 (rank : 175)
Query Neighborhood Hits	154	Target Neighborhood Hits	378	Shared Neighborhood Hits	43
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

PCSK5_HUMAN
θ value	0.62314 (rank : 86)	NC score	0.046343 (rank : 136)
Query Neighborhood Hits	154	Target Neighborhood Hits	291	Shared Neighborhood Hits	55
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

STAB2_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.075151 (rank : 62)
Query Neighborhood Hits	154	Target Neighborhood Hits	528	Shared Neighborhood Hits	76
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TNR5_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.029911 (rank : 173)
Query Neighborhood Hits	154	Target Neighborhood Hits	102	Shared Neighborhood Hits	25
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

CREL1_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.081464 (rank : 59)
Query Neighborhood Hits	154	Target Neighborhood Hits	441	Shared Neighborhood Hits	51
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EPHA1_MOUSE
θ value	0.813845 (rank : 90)	NC score	0.036528 (rank : 159)
Query Neighborhood Hits	154	Target Neighborhood Hits	958	Shared Neighborhood Hits	55
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA4_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.037079 (rank : 157)
Query Neighborhood Hits	154	Target Neighborhood Hits	975	Shared Neighborhood Hits	47
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

LTBP2_MOUSE
θ value	0.813845 (rank : 92)	NC score	0.064476 (rank : 70)
Query Neighborhood Hits	154	Target Neighborhood Hits	617	Shared Neighborhood Hits	70
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TACD2_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.150782 (rank : 54)
Query Neighborhood Hits	154	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

ZAN_MOUSE
θ value	0.813845 (rank : 94)	NC score	0.051592 (rank : 120)
Query Neighborhood Hits	154	Target Neighborhood Hits	808	Shared Neighborhood Hits	60
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

EPHA8_MOUSE
θ value	1.06291 (rank : 95)	NC score	0.034884 (rank : 161)
Query Neighborhood Hits	154	Target Neighborhood Hits	969	Shared Neighborhood Hits	40
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

UTP20_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.018263 (rank : 182)
Query Neighborhood Hits	154	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

EPHA6_MOUSE
θ value	1.38821 (rank : 97)	NC score	0.040816 (rank : 148)
Query Neighborhood Hits	154	Target Neighborhood Hits	946	Shared Neighborhood Hits	48
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

LAMA1_HUMAN
θ value	1.38821 (rank : 98)	NC score	0.056381 (rank : 87)
Query Neighborhood Hits	154	Target Neighborhood Hits	804	Shared Neighborhood Hits	75
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

EPHA7_MOUSE
θ value	1.81305 (rank : 99)	NC score	0.037341 (rank : 155)
Query Neighborhood Hits	154	Target Neighborhood Hits	1025	Shared Neighborhood Hits	60
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHAA_HUMAN
θ value	1.81305 (rank : 100)	NC score	0.041919 (rank : 145)
Query Neighborhood Hits	154	Target Neighborhood Hits	960	Shared Neighborhood Hits	51
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

IRS2_MOUSE
θ value	1.81305 (rank : 101)	NC score	0.014891 (rank : 183)
Query Neighborhood Hits	154	Target Neighborhood Hits	248	Shared Neighborhood Hits	5
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

PMS2_HUMAN
θ value	1.81305 (rank : 102)	NC score	0.014670 (rank : 184)
Query Neighborhood Hits	154	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

TNR4_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.042471 (rank : 142)
Query Neighborhood Hits	154	Target Neighborhood Hits	152	Shared Neighborhood Hits	38
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

FRAS1_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.042176 (rank : 143)
Query Neighborhood Hits	154	Target Neighborhood Hits	759	Shared Neighborhood Hits	66
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

TMCC1_HUMAN
θ value	2.36792 (rank : 105)	NC score	0.011954 (rank : 185)
Query Neighborhood Hits	154	Target Neighborhood Hits	337	Shared Neighborhood Hits	5
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TNR16_MOUSE
θ value	2.36792 (rank : 106)	NC score	0.048612 (rank : 132)
Query Neighborhood Hits	154	Target Neighborhood Hits	178	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

DTNB_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.007746 (rank : 190)
Query Neighborhood Hits	154	Target Neighborhood Hits	263	Shared Neighborhood Hits	2
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

IGF1R_MOUSE
θ value	3.0926 (rank : 108)	NC score	0.021344 (rank : 178)
Query Neighborhood Hits	154	Target Neighborhood Hits	973	Shared Neighborhood Hits	48
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

LAMA2_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.051202 (rank : 124)
Query Neighborhood Hits	154	Target Neighborhood Hits	1092	Shared Neighborhood Hits	73
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LTBP2_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.058721 (rank : 80)
Query Neighborhood Hits	154	Target Neighborhood Hits	552	Shared Neighborhood Hits	69
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

OR2D3_HUMAN
θ value	3.0926 (rank : 111)	NC score	-0.004723 (rank : 203)
Query Neighborhood Hits	154	Target Neighborhood Hits	812	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGH3, Q96R51	Gene names	OR2D3
Domain Architecture
Description	Olfactory receptor 2D3.

SSPO_MOUSE
θ value	3.0926 (rank : 112)	NC score	0.029704 (rank : 174)
Query Neighborhood Hits	154	Target Neighborhood Hits	800	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

USH2A_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.055432 (rank : 92)
Query Neighborhood Hits	154	Target Neighborhood Hits	600	Shared Neighborhood Hits	82
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

CASR_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.009491 (rank : 189)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CRIM1_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.042825 (rank : 141)
Query Neighborhood Hits	154	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

EPHA3_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.034437 (rank : 165)
Query Neighborhood Hits	154	Target Neighborhood Hits	1005	Shared Neighborhood Hits	54
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

KLK4_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.000033 (rank : 200)
Query Neighborhood Hits	154	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

LAMB3_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.043890 (rank : 139)
Query Neighborhood Hits	154	Target Neighborhood Hits	461	Shared Neighborhood Hits	48
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

TNR9_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.058099 (rank : 81)
Query Neighborhood Hits	154	Target Neighborhood Hits	166	Shared Neighborhood Hits	49
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TTPA_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.009781 (rank : 188)
Query Neighborhood Hits	154	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P49638, Q71V64	Gene names	TTPA, TPP1
Domain Architecture
Description	Alpha-tocopherol transfer protein (Alpha-TTP).

IGF1R_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.020585 (rank : 179)
Query Neighborhood Hits	154	Target Neighborhood Hits	977	Shared Neighborhood Hits	43
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

LRRN1_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.000003 (rank : 201)
Query Neighborhood Hits	154	Target Neighborhood Hits	508	Shared Neighborhood Hits	5
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LY10_HUMAN
θ value	5.27518 (rank : 123)	NC score	0.007651 (rank : 191)
Query Neighborhood Hits	154	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

SOX13_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.003679 (rank : 196)
Query Neighborhood Hits	154	Target Neighborhood Hits	464	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

TMCC1_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.010229 (rank : 186)
Query Neighborhood Hits	154	Target Neighborhood Hits	315	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TNR5_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.031931 (rank : 170)
Query Neighborhood Hits	154	Target Neighborhood Hits	131	Shared Neighborhood Hits	34
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

V2RX_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.006973 (rank : 192)
Query Neighborhood Hits	154	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

WIF1_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.047408 (rank : 134)
Query Neighborhood Hits	154	Target Neighborhood Hits	393	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ASTN_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.022151 (rank : 177)
Query Neighborhood Hits	154	Target Neighborhood Hits	98	Shared Neighborhood Hits	14
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

CO2_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.002319 (rank : 199)
Query Neighborhood Hits	154	Target Neighborhood Hits	258	Shared Neighborhood Hits	5
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

EPHA2_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.034525 (rank : 164)
Query Neighborhood Hits	154	Target Neighborhood Hits	1021	Shared Neighborhood Hits	52
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA6_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.040220 (rank : 150)
Query Neighborhood Hits	154	Target Neighborhood Hits	959	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB1_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.034264 (rank : 166)
Query Neighborhood Hits	154	Target Neighborhood Hits	988	Shared Neighborhood Hits	53
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

KV1L_HUMAN
θ value	6.88961 (rank : 134)	NC score	-0.000992 (rank : 202)
Query Neighborhood Hits	154	Target Neighborhood Hits	239	Shared Neighborhood Hits	2
SwissProt Accessions	P01604	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Kue.

LAMA5_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.060342 (rank : 78)
Query Neighborhood Hits	154	Target Neighborhood Hits	828	Shared Neighborhood Hits	80
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

PGBM_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.033372 (rank : 169)
Query Neighborhood Hits	154	Target Neighborhood Hits	1073	Shared Neighborhood Hits	71
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SRGP2_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.003156 (rank : 197)
Query Neighborhood Hits	154	Target Neighborhood Hits	331	Shared Neighborhood Hits	4
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

STAB2_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.068155 (rank : 66)
Query Neighborhood Hits	154	Target Neighborhood Hits	534	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TNR16_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.048441 (rank : 133)
Query Neighborhood Hits	154	Target Neighborhood Hits	183	Shared Neighborhood Hits	48
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR1A_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.018341 (rank : 181)
Query Neighborhood Hits	154	Target Neighborhood Hits	131	Shared Neighborhood Hits	23
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

VWF_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.024127 (rank : 176)
Query Neighborhood Hits	154	Target Neighborhood Hits	381	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ATP5S_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.009850 (rank : 187)
Query Neighborhood Hits	154	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q99766, Q8WWX3	Gene names	ATP5S, ATPW
Domain Architecture	No domain graphic available
Description	ATP synthase subunit s, mitochondrial precursor (ATP synthase coupling factor B) (Mitochondrial ATP synthase regulatory component factor B).

CAZA3_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.006250 (rank : 193)
Query Neighborhood Hits	154	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KX2, Q969J0	Gene names	CAPZA3, CAPAA3, GSG3
Domain Architecture
Description	F-actin capping protein alpha-3 subunit (CapZ alpha-3) (CP-alpha-3) (Germ cell-specific protein 3).

EPHA3_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.034151 (rank : 167)
Query Neighborhood Hits	154	Target Neighborhood Hits	1009	Shared Neighborhood Hits	51
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

KPB1_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.004277 (rank : 195)
Query Neighborhood Hits	154	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P18826	Gene names	Phka1
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit).

LAMB2_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.052359 (rank : 117)
Query Neighborhood Hits	154	Target Neighborhood Hits	722	Shared Neighborhood Hits	70
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.041182 (rank : 146)
Query Neighborhood Hits	154	Target Neighborhood Hits	444	Shared Neighborhood Hits	48
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LTBP4_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.055528 (rank : 90)
Query Neighborhood Hits	154	Target Neighborhood Hits	607	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NOTC3_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.046027 (rank : 137)
Query Neighborhood Hits	154	Target Neighborhood Hits	975	Shared Neighborhood Hits	56
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PRG3_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.005259 (rank : 194)
Query Neighborhood Hits	154	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

SRGP2_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.002765 (rank : 198)
Query Neighborhood Hits	154	Target Neighborhood Hits	324	Shared Neighborhood Hits	3
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

STAB1_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.060394 (rank : 77)
Query Neighborhood Hits	154	Target Neighborhood Hits	566	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TNR19_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.020368 (rank : 180)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR3_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.033544 (rank : 168)
Query Neighborhood Hits	154	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

AAAD_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.178834 (rank : 51)
Query Neighborhood Hits	154	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AAAD_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.098907 (rank : 57)
Query Neighborhood Hits	154	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AGRIN_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.066569 (rank : 67)
Query Neighborhood Hits	154	Target Neighborhood Hits	582	Shared Neighborhood Hits	67
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

C1QR1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.055071 (rank : 94)
Query Neighborhood Hits	154	Target Neighborhood Hits	493	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.054598 (rank : 98)
Query Neighborhood Hits	154	Target Neighborhood Hits	342	Shared Neighborhood Hits	48
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CREL1_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.075880 (rank : 61)
Query Neighborhood Hits	154	Target Neighborhood Hits	524	Shared Neighborhood Hits	51
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGF_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.053990 (rank : 103)
Query Neighborhood Hits	154	Target Neighborhood Hits	343	Shared Neighborhood Hits	46
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.055514 (rank : 91)
Query Neighborhood Hits	154	Target Neighborhood Hits	358	Shared Neighborhood Hits	47
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FBLN2_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.055608 (rank : 89)
Query Neighborhood Hits	154	Target Neighborhood Hits	392	Shared Neighborhood Hits	46
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.055647 (rank : 88)
Query Neighborhood Hits	154	Target Neighborhood Hits	505	Shared Neighborhood Hits	48
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN3_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.051868 (rank : 118)
Query Neighborhood Hits	154	Target Neighborhood Hits	293	Shared Neighborhood Hits	45
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.050930 (rank : 126)
Query Neighborhood Hits	154	Target Neighborhood Hits	279	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.051731 (rank : 119)
Query Neighborhood Hits	154	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.051456 (rank : 122)
Query Neighborhood Hits	154	Target Neighborhood Hits	270	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.052383 (rank : 116)
Query Neighborhood Hits	154	Target Neighborhood Hits	329	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.053232 (rank : 109)
Query Neighborhood Hits	154	Target Neighborhood Hits	317	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FBN1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.052900 (rank : 111)
Query Neighborhood Hits	154	Target Neighborhood Hits	557	Shared Neighborhood Hits	67
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.052608 (rank : 114)
Query Neighborhood Hits	154	Target Neighborhood Hits	563	Shared Neighborhood Hits	67
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.053629 (rank : 105)
Query Neighborhood Hits	154	Target Neighborhood Hits	560	Shared Neighborhood Hits	67
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.052537 (rank : 115)
Query Neighborhood Hits	154	Target Neighborhood Hits	549	Shared Neighborhood Hits	63
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.054090 (rank : 101)
Query Neighborhood Hits	154	Target Neighborhood Hits	543	Shared Neighborhood Hits	67
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FST_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.050087 (rank : 129)
Query Neighborhood Hits	154	Target Neighborhood Hits	129	Shared Neighborhood Hits	20
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

GAS6_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.050958 (rank : 125)
Query Neighborhood Hits	154	Target Neighborhood Hits	348	Shared Neighborhood Hits	42
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

LAMC3_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.056418 (rank : 86)
Query Neighborhood Hits	154	Target Neighborhood Hits	588	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.054629 (rank : 97)
Query Neighborhood Hits	154	Target Neighborhood Hits	624	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LRP8_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.051420 (rank : 123)
Query Neighborhood Hits	154	Target Neighborhood Hits	346	Shared Neighborhood Hits	42
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.051572 (rank : 121)
Query Neighborhood Hits	154	Target Neighborhood Hits	385	Shared Neighborhood Hits	48
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTB1S_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.050027 (rank : 130)
Query Neighborhood Hits	154	Target Neighborhood Hits	502	Shared Neighborhood Hits	55
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.052676 (rank : 113)
Query Neighborhood Hits	154	Target Neighborhood Hits	502	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.057016 (rank : 84)
Query Neighborhood Hits	154	Target Neighborhood Hits	475	Shared Neighborhood Hits	62
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MEGF8_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.062587 (rank : 74)
Query Neighborhood Hits	154	Target Neighborhood Hits	528	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.061667 (rank : 75)
Query Neighborhood Hits	154	Target Neighborhood Hits	520	Shared Neighborhood Hits	55
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

NELL1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.055167 (rank : 93)
Query Neighborhood Hits	154	Target Neighborhood Hits	451	Shared Neighborhood Hits	49
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.054039 (rank : 102)
Query Neighborhood Hits	154	Target Neighborhood Hits	449	Shared Neighborhood Hits	49
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.054245 (rank : 99)
Query Neighborhood Hits	154	Target Neighborhood Hits	436	Shared Neighborhood Hits	51
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

PROS_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.050628 (rank : 127)
Query Neighborhood Hits	154	Target Neighborhood Hits	330	Shared Neighborhood Hits	43
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SMR3B_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.057618 (rank : 82)
Query Neighborhood Hits	154	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SPRC_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.065342 (rank : 68)
Query Neighborhood Hits	154	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.064614 (rank : 69)
Query Neighborhood Hits	154	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRL1_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.053881 (rank : 104)
Query Neighborhood Hits	154	Target Neighborhood Hits	231	Shared Neighborhood Hits	11
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SREC2_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.052732 (rank : 112)
Query Neighborhood Hits	154	Target Neighborhood Hits	645	Shared Neighborhood Hits	63
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.053582 (rank : 106)
Query Neighborhood Hits	154	Target Neighborhood Hits	605	Shared Neighborhood Hits	59
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.054720 (rank : 96)
Query Neighborhood Hits	154	Target Neighborhood Hits	645	Shared Neighborhood Hits	63
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.060866 (rank : 76)
Query Neighborhood Hits	154	Target Neighborhood Hits	546	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TRBM_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.053498 (rank : 107)
Query Neighborhood Hits	154	Target Neighborhood Hits	339	Shared Neighborhood Hits	42
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.056725 (rank : 85)
Query Neighborhood Hits	154	Target Neighborhood Hits	361	Shared Neighborhood Hits	53
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

UROM_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.053002 (rank : 110)
Query Neighborhood Hits	154	Target Neighborhood Hits	284	Shared Neighborhood Hits	37
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.053343 (rank : 108)
Query Neighborhood Hits	154	Target Neighborhood Hits	276	Shared Neighborhood Hits	41
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.054207 (rank : 100)
Query Neighborhood Hits	154	Target Neighborhood Hits	626	Shared Neighborhood Hits	77
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

Hits sorted by NC score

THYG_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	154	Target Neighborhood Hits	154	Shared Neighborhood Hits	154
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

THYG_MOUSE
NC score	0.990719 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	154	Target Neighborhood Hits	161	Shared Neighborhood Hits	106
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

ACES_HUMAN
NC score	0.832330 (rank : 3)	θ value	4.53632e-60 (rank : 3)
Query Neighborhood Hits	154	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_MOUSE
NC score	0.831553 (rank : 4)	θ value	2.32979e-56 (rank : 5)
Query Neighborhood Hits	154	Target Neighborhood Hits	29	Shared Neighborhood Hits	23
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

CHLE_MOUSE
NC score	0.831303 (rank : 5)	θ value	2.48917e-58 (rank : 4)
Query Neighborhood Hits	154	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CHLE_HUMAN
NC score	0.828352 (rank : 6)	θ value	1.08223e-53 (rank : 6)
Query Neighborhood Hits	154	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

EST2_HUMAN
NC score	0.815758 (rank : 7)	θ value	3.48949e-44 (rank : 7)
Query Neighborhood Hits	154	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

CEL_MOUSE
NC score	0.813388 (rank : 8)	θ value	4.41421e-39 (rank : 16)
Query Neighborhood Hits	154	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EST31_MOUSE
NC score	0.809986 (rank : 9)	θ value	6.15952e-41 (rank : 14)
Query Neighborhood Hits	154	Target Neighborhood Hits	31	Shared Neighborhood Hits	23
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

EST22_MOUSE
NC score	0.798456 (rank : 10)	θ value	1.85459e-37 (rank : 21)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

CES3_MOUSE
NC score	0.798023 (rank : 11)	θ value	7.52953e-39 (rank : 17)
Query Neighborhood Hits	154	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

ESTN_MOUSE
NC score	0.796597 (rank : 12)	θ value	2.26708e-35 (rank : 23)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

EST1_MOUSE
NC score	0.796199 (rank : 13)	θ value	3.37985e-39 (rank : 15)
Query Neighborhood Hits	154	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

EST1_HUMAN
NC score	0.796092 (rank : 14)	θ value	7.04741e-37 (rank : 22)
Query Neighborhood Hits	154	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

NLGN2_HUMAN
NC score	0.793576 (rank : 15)	θ value	2.50074e-42 (rank : 11)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
NC score	0.793139 (rank : 16)	θ value	7.27602e-42 (rank : 12)
Query Neighborhood Hits	154	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN3_MOUSE
NC score	0.791138 (rank : 17)	θ value	3.85808e-43 (rank : 8)
Query Neighborhood Hits	154	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGNY_HUMAN
NC score	0.791087 (rank : 18)	θ value	5.03882e-43 (rank : 10)
Query Neighborhood Hits	154	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

NLGNX_HUMAN
NC score	0.790827 (rank : 19)	θ value	5.03882e-43 (rank : 9)
Query Neighborhood Hits	154	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGN3_HUMAN
NC score	0.789427 (rank : 20)	θ value	3.61106e-41 (rank : 13)
Query Neighborhood Hits	154	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN1_MOUSE
NC score	0.785310 (rank : 21)	θ value	3.73686e-38 (rank : 20)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	23
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN1_HUMAN
NC score	0.785152 (rank : 22)	θ value	1.28434e-38 (rank : 18)
Query Neighborhood Hits	154	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

CEL_HUMAN
NC score	0.614022 (rank : 23)	θ value	2.19075e-38 (rank : 19)
Query Neighborhood Hits	154	Target Neighborhood Hits	896	Shared Neighborhood Hits	30
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

SMOC2_MOUSE
NC score	0.369060 (rank : 24)	θ value	2.60593e-15 (rank : 27)
Query Neighborhood Hits	154	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC2_HUMAN
NC score	0.368028 (rank : 25)	θ value	1.99529e-15 (rank : 26)
Query Neighborhood Hits	154	Target Neighborhood Hits	88	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC1_HUMAN
NC score	0.354841 (rank : 26)	θ value	1.86753e-13 (rank : 28)
Query Neighborhood Hits	154	Target Neighborhood Hits	81	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
NC score	0.347707 (rank : 27)	θ value	2.0648e-12 (rank : 29)
Query Neighborhood Hits	154	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

HG2A_MOUSE
NC score	0.308268 (rank : 28)	θ value	1.43324e-05 (rank : 41)
Query Neighborhood Hits	154	Target Neighborhood Hits	36	Shared Neighborhood Hits	32
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

HG2A_HUMAN
NC score	0.293543 (rank : 29)	θ value	9.29e-05 (rank : 42)
Query Neighborhood Hits	154	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

TICN1_HUMAN
NC score	0.279471 (rank : 30)	θ value	1.29631e-06 (rank : 36)
Query Neighborhood Hits	154	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN2_HUMAN
NC score	0.278863 (rank : 31)	θ value	1.69304e-06 (rank : 38)
Query Neighborhood Hits	154	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN1_MOUSE
NC score	0.278488 (rank : 32)	θ value	1.29631e-06 (rank : 37)
Query Neighborhood Hits	154	Target Neighborhood Hits	79	Shared Neighborhood Hits	34
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN2_MOUSE
NC score	0.277046 (rank : 33)	θ value	2.21117e-06 (rank : 39)
Query Neighborhood Hits	154	Target Neighborhood Hits	69	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN3_HUMAN
NC score	0.273965 (rank : 34)	θ value	5.81887e-07 (rank : 34)
Query Neighborhood Hits	154	Target Neighborhood Hits	82	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_MOUSE
NC score	0.270708 (rank : 35)	θ value	9.92553e-07 (rank : 35)
Query Neighborhood Hits	154	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

IBP6_HUMAN
NC score	0.261056 (rank : 36)	θ value	6.43352e-06 (rank : 40)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP1_HUMAN
NC score	0.239089 (rank : 37)	θ value	0.000158464 (rank : 43)
Query Neighborhood Hits	154	Target Neighborhood Hits	67	Shared Neighborhood Hits	36
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP6_MOUSE
NC score	0.231581 (rank : 38)	θ value	0.00509761 (rank : 50)
Query Neighborhood Hits	154	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP3_HUMAN
NC score	0.228967 (rank : 39)	θ value	0.00390308 (rank : 49)
Query Neighborhood Hits	154	Target Neighborhood Hits	67	Shared Neighborhood Hits	34
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP1_MOUSE
NC score	0.227822 (rank : 40)	θ value	0.000158464 (rank : 44)
Query Neighborhood Hits	154	Target Neighborhood Hits	97	Shared Neighborhood Hits	36
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP4_MOUSE
NC score	0.221341 (rank : 41)	θ value	0.00228821 (rank : 47)
Query Neighborhood Hits	154	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_HUMAN
NC score	0.220118 (rank : 42)	θ value	0.00228821 (rank : 46)
Query Neighborhood Hits	154	Target Neighborhood Hits	52	Shared Neighborhood Hits	33
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP3_MOUSE
NC score	0.217543 (rank : 43)	θ value	0.0193708 (rank : 57)
Query Neighborhood Hits	154	Target Neighborhood Hits	60	Shared Neighborhood Hits	35
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP5_HUMAN
NC score	0.217037 (rank : 44)	θ value	0.00102713 (rank : 45)
Query Neighborhood Hits	154	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
NC score	0.216809 (rank : 45)	θ value	0.00228821 (rank : 48)
Query Neighborhood Hits	154	Target Neighborhood Hits	68	Shared Neighborhood Hits	33
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP2_MOUSE
NC score	0.205324 (rank : 46)	θ value	0.0113563 (rank : 54)
Query Neighborhood Hits	154	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

NID2_HUMAN
NC score	0.203295 (rank : 47)	θ value	3.07829e-16 (rank : 24)
Query Neighborhood Hits	154	Target Neighborhood Hits	456	Shared Neighborhood Hits	75
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
NC score	0.201121 (rank : 48)	θ value	4.02038e-16 (rank : 25)
Query Neighborhood Hits	154	Target Neighborhood Hits	338	Shared Neighborhood Hits	71
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

IBP2_HUMAN
NC score	0.194486 (rank : 49)	θ value	0.0252991 (rank : 58)
Query Neighborhood Hits	154	Target Neighborhood Hits	61	Shared Neighborhood Hits	33
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

TACD1_HUMAN
NC score	0.187139 (rank : 50)	θ value	0.0736092 (rank : 64)
Query Neighborhood Hits	154	Target Neighborhood Hits	34	Shared Neighborhood Hits	33
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

AAAD_HUMAN
NC score	0.178834 (rank : 51)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	154	Target Neighborhood Hits	22	Shared Neighborhood Hits	15
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

NID1_HUMAN
NC score	0.176065 (rank : 52)	θ value	3.08544e-08 (rank : 33)
Query Neighborhood Hits	154	Target Neighborhood Hits	329	Shared Neighborhood Hits	71
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
NC score	0.173235 (rank : 53)	θ value	1.38499e-08 (rank : 30)
Query Neighborhood Hits	154	Target Neighborhood Hits	335	Shared Neighborhood Hits	69
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TACD2_HUMAN
NC score	0.150782 (rank : 54)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	154	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

SCUB3_HUMAN
NC score	0.110537 (rank : 55)	θ value	1.38499e-08 (rank : 31)
Query Neighborhood Hits	154	Target Neighborhood Hits	428	Shared Neighborhood Hits	76
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
NC score	0.110285 (rank : 56)	θ value	1.38499e-08 (rank : 32)
Query Neighborhood Hits	154	Target Neighborhood Hits	442	Shared Neighborhood Hits	74
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

AAAD_MOUSE
NC score	0.098907 (rank : 57)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	154	Target Neighborhood Hits	24	Shared Neighborhood Hits	14
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

MEGF9_HUMAN
NC score	0.086224 (rank : 58)	θ value	0.0148317 (rank : 55)
Query Neighborhood Hits	154	Target Neighborhood Hits	557	Shared Neighborhood Hits	70
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

CREL1_HUMAN
NC score	0.081464 (rank : 59)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	154	Target Neighborhood Hits	441	Shared Neighborhood Hits	51
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LAMC2_MOUSE
NC score	0.076600 (rank : 60)	θ value	0.00509761 (rank : 53)
Query Neighborhood Hits	154	Target Neighborhood Hits	614	Shared Neighborhood Hits	76
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

CREL1_MOUSE
NC score	0.075880 (rank : 61)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	154	Target Neighborhood Hits	524	Shared Neighborhood Hits	51
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

STAB2_MOUSE
NC score	0.075151 (rank : 62)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	154	Target Neighborhood Hits	528	Shared Neighborhood Hits	76
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

MEGF9_MOUSE
NC score	0.074512 (rank : 63)	θ value	0.0563607 (rank : 60)
Query Neighborhood Hits	154	Target Neighborhood Hits	896	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LAMC2_HUMAN
NC score	0.071417 (rank : 64)	θ value	0.00509761 (rank : 52)
Query Neighborhood Hits	154	Target Neighborhood Hits	715	Shared Neighborhood Hits	74
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

MEGF6_HUMAN
NC score	0.070377 (rank : 65)	θ value	0.0736092 (rank : 63)
Query Neighborhood Hits	154	Target Neighborhood Hits	671	Shared Neighborhood Hits	79
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

STAB2_HUMAN
NC score	0.068155 (rank : 66)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	154	Target Neighborhood Hits	534	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

AGRIN_HUMAN
NC score	0.066569 (rank : 67)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	154	Target Neighborhood Hits	582	Shared Neighborhood Hits	67
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

SPRC_HUMAN
NC score	0.065342 (rank : 68)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	154	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
NC score	0.064614 (rank : 69)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	154	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

LTBP2_MOUSE
NC score	0.064476 (rank : 70)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	154	Target Neighborhood Hits	617	Shared Neighborhood Hits	70
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LAMA5_HUMAN
NC score	0.064014 (rank : 71)	θ value	0.00509761 (rank : 51)
Query Neighborhood Hits	154	Target Neighborhood Hits	976	Shared Neighborhood Hits	78
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FBLN1_MOUSE
NC score	0.063709 (rank : 72)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	154	Target Neighborhood Hits	329	Shared Neighborhood Hits	52
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN1_HUMAN
NC score	0.063173 (rank : 73)	θ value	0.0563607 (rank : 59)
Query Neighborhood Hits	154	Target Neighborhood Hits	324	Shared Neighborhood Hits	49
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

MEGF8_HUMAN
NC score	0.062587 (rank : 74)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	154	Target Neighborhood Hits	528	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
NC score	0.061667 (rank : 75)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	154	Target Neighborhood Hits	520	Shared Neighborhood Hits	55
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

STAB1_HUMAN
NC score	0.060866 (rank : 76)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	154	Target Neighborhood Hits	546	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
NC score	0.060394 (rank : 77)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	154	Target Neighborhood Hits	566	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

LAMA5_MOUSE
NC score	0.060342 (rank : 78)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	154	Target Neighborhood Hits	828	Shared Neighborhood Hits	80
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA1_MOUSE
NC score	0.059668 (rank : 79)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	154	Target Neighborhood Hits	838	Shared Neighborhood Hits	76
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LTBP2_HUMAN
NC score	0.058721 (rank : 80)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	154	Target Neighborhood Hits	552	Shared Neighborhood Hits	69
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

TNR9_HUMAN
NC score	0.058099 (rank : 81)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	154	Target Neighborhood Hits	166	Shared Neighborhood Hits	49
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

SMR3B_HUMAN
NC score	0.057618 (rank : 82)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	154	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

LAMA3_MOUSE
NC score	0.057375 (rank : 83)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	154	Target Neighborhood Hits	859	Shared Neighborhood Hits	68
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LTBP3_MOUSE
NC score	0.057016 (rank : 84)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	154	Target Neighborhood Hits	475	Shared Neighborhood Hits	62
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TRBM_MOUSE
NC score	0.056725 (rank : 85)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	154	Target Neighborhood Hits	361	Shared Neighborhood Hits	53
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LAMC3_HUMAN
NC score	0.056418 (rank : 86)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	154	Target Neighborhood Hits	588	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA1_HUMAN
NC score	0.056381 (rank : 87)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	154	Target Neighborhood Hits	804	Shared Neighborhood Hits	75
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

FBLN2_MOUSE
NC score	0.055647 (rank : 88)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	154	Target Neighborhood Hits	505	Shared Neighborhood Hits	48
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_HUMAN
NC score	0.055608 (rank : 89)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	154	Target Neighborhood Hits	392	Shared Neighborhood Hits	46
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LTBP4_MOUSE
NC score	0.055528 (rank : 90)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	154	Target Neighborhood Hits	607	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

EGF_MOUSE
NC score	0.055514 (rank : 91)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	154	Target Neighborhood Hits	358	Shared Neighborhood Hits	47
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

USH2A_HUMAN
NC score	0.055432 (rank : 92)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	154	Target Neighborhood Hits	600	Shared Neighborhood Hits	82
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

NELL1_HUMAN
NC score	0.055167 (rank : 93)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	154	Target Neighborhood Hits	451	Shared Neighborhood Hits	49
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

C1QR1_HUMAN
NC score	0.055071 (rank : 94)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	154	Target Neighborhood Hits	493	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

PCSK5_MOUSE
NC score	0.054885 (rank : 95)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	154	Target Neighborhood Hits	613	Shared Neighborhood Hits	70
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

SREC_HUMAN
NC score	0.054720 (rank : 96)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	154	Target Neighborhood Hits	645	Shared Neighborhood Hits	63
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

LAMC3_MOUSE
NC score	0.054629 (rank : 97)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	154	Target Neighborhood Hits	624	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

C1QR1_MOUSE
NC score	0.054598 (rank : 98)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	154	Target Neighborhood Hits	342	Shared Neighborhood Hits	48
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

NELL2_MOUSE
NC score	0.054245 (rank : 99)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	154	Target Neighborhood Hits	436	Shared Neighborhood Hits	51
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

USH2A_MOUSE
NC score	0.054207 (rank : 100)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	154	Target Neighborhood Hits	626	Shared Neighborhood Hits	77
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

FBN3_HUMAN
NC score	0.054090 (rank : 101)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	154	Target Neighborhood Hits	543	Shared Neighborhood Hits	67
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

NELL2_HUMAN
NC score	0.054039 (rank : 102)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	154	Target Neighborhood Hits	449	Shared Neighborhood Hits	49
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

EGF_HUMAN
NC score	0.053990 (rank : 103)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	154	Target Neighborhood Hits	343	Shared Neighborhood Hits	46
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

SPRL1_HUMAN
NC score	0.053881 (rank : 104)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	154	Target Neighborhood Hits	231	Shared Neighborhood Hits	11
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

FBN2_HUMAN
NC score	0.053629 (rank : 105)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	154	Target Neighborhood Hits	560	Shared Neighborhood Hits	67
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

SREC2_MOUSE
NC score	0.053582 (rank : 106)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	154	Target Neighborhood Hits	605	Shared Neighborhood Hits	59
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TRBM_HUMAN
NC score	0.053498 (rank : 107)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	154	Target Neighborhood Hits	339	Shared Neighborhood Hits	42
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

UROM_MOUSE
NC score	0.053343 (rank : 108)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	154	Target Neighborhood Hits	276	Shared Neighborhood Hits	41
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FBLN5_MOUSE
NC score	0.053232 (rank : 109)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	154	Target Neighborhood Hits	317	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

UROM_HUMAN
NC score	0.053002 (rank : 110)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	154	Target Neighborhood Hits	284	Shared Neighborhood Hits	37
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

FBN1_HUMAN
NC score	0.052900 (rank : 111)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	154	Target Neighborhood Hits	557	Shared Neighborhood Hits	67
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

SREC2_HUMAN
NC score	0.052732 (rank : 112)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	154	Target Neighborhood Hits	645	Shared Neighborhood Hits	63
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

LTBP3_HUMAN
NC score	0.052676 (rank : 113)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	154	Target Neighborhood Hits	502	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBN1_MOUSE
NC score	0.052608 (rank : 114)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	154	Target Neighborhood Hits	563	Shared Neighborhood Hits	67
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
NC score	0.052537 (rank : 115)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	154	Target Neighborhood Hits	549	Shared Neighborhood Hits	63
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBLN5_HUMAN
NC score	0.052383 (rank : 116)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	154	Target Neighborhood Hits	329	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

LAMB2_MOUSE
NC score	0.052359 (rank : 117)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	154	Target Neighborhood Hits	722	Shared Neighborhood Hits	70
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

FBLN3_HUMAN
NC score	0.051868 (rank : 118)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	154	Target Neighborhood Hits	293	Shared Neighborhood Hits	45
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN4_HUMAN
NC score	0.051731 (rank : 119)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	154	Target Neighborhood Hits	278	Shared Neighborhood Hits	44
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

ZAN_MOUSE
NC score	0.051592 (rank : 120)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	154	Target Neighborhood Hits	808	Shared Neighborhood Hits	60
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

LRP8_MOUSE
NC score	0.051572 (rank : 121)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	154	Target Neighborhood Hits	385	Shared Neighborhood Hits	48
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

FBLN4_MOUSE
NC score	0.051456 (rank : 122)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	154	Target Neighborhood Hits	270	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

LRP8_HUMAN
NC score	0.051420 (rank : 123)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	154	Target Neighborhood Hits	346	Shared Neighborhood Hits	42
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LAMA2_HUMAN
NC score	0.051202 (rank : 124)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	154	Target Neighborhood Hits	1092	Shared Neighborhood Hits	73
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

GAS6_HUMAN
NC score	0.050958 (rank : 125)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	154	Target Neighborhood Hits	348	Shared Neighborhood Hits	42
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

FBLN3_MOUSE
NC score	0.050930 (rank : 126)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	154	Target Neighborhood Hits	279	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

PROS_MOUSE
NC score	0.050628 (rank : 127)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	154	Target Neighborhood Hits	330	Shared Neighborhood Hits	43
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

NOTC3_HUMAN
NC score	0.050120 (rank : 128)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	154	Target Neighborhood Hits	1062	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FST_HUMAN
NC score	0.050087 (rank : 129)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	154	Target Neighborhood Hits	129	Shared Neighborhood Hits	20
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

LTB1S_HUMAN
NC score	0.050027 (rank : 130)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	154	Target Neighborhood Hits	502	Shared Neighborhood Hits	55
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

EPHB6_HUMAN
NC score	0.049562 (rank : 131)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	154	Target Neighborhood Hits	912	Shared Neighborhood Hits	54
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

TNR16_MOUSE
NC score	0.048612 (rank : 132)	θ value	2.36792 (rank : 106)
Query Neighborhood Hits	154	Target Neighborhood Hits	178	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR16_HUMAN
NC score	0.048441 (rank : 133)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	154	Target Neighborhood Hits	183	Shared Neighborhood Hits	48
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

WIF1_MOUSE
NC score	0.047408 (rank : 134)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	154	Target Neighborhood Hits	393	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

EPHB6_MOUSE
NC score	0.046909 (rank : 135)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	154	Target Neighborhood Hits	906	Shared Neighborhood Hits	47
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

PCSK5_HUMAN
NC score	0.046343 (rank : 136)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	154	Target Neighborhood Hits	291	Shared Neighborhood Hits	55
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

NOTC3_MOUSE
NC score	0.046027 (rank : 137)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	154	Target Neighborhood Hits	975	Shared Neighborhood Hits	56
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

EPHB3_HUMAN
NC score	0.044059 (rank : 138)	θ value	0.0193708 (rank : 56)
Query Neighborhood Hits	154	Target Neighborhood Hits	996	Shared Neighborhood Hits	56
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

LAMB3_HUMAN
NC score	0.043890 (rank : 139)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	154	Target Neighborhood Hits	461	Shared Neighborhood Hits	48
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

EPHB4_HUMAN
NC score	0.042970 (rank : 140)	θ value	0.0736092 (rank : 61)
Query Neighborhood Hits	154	Target Neighborhood Hits	1056	Shared Neighborhood Hits	62
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

CRIM1_HUMAN
NC score	0.042825 (rank : 141)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	154	Target Neighborhood Hits	362	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

TNR4_HUMAN
NC score	0.042471 (rank : 142)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	154	Target Neighborhood Hits	152	Shared Neighborhood Hits	38
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

FRAS1_HUMAN
NC score	0.042176 (rank : 143)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	154	Target Neighborhood Hits	759	Shared Neighborhood Hits	66
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

EPHB3_MOUSE
NC score	0.042087 (rank : 144)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	154	Target Neighborhood Hits	996	Shared Neighborhood Hits	50
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHAA_HUMAN
NC score	0.041919 (rank : 145)	θ value	1.81305 (rank : 100)
Query Neighborhood Hits	154	Target Neighborhood Hits	960	Shared Neighborhood Hits	51
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

LAMB3_MOUSE
NC score	0.041182 (rank : 146)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	154	Target Neighborhood Hits	444	Shared Neighborhood Hits	48
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

EPHA7_HUMAN
NC score	0.041147 (rank : 147)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	154	Target Neighborhood Hits	1053	Shared Neighborhood Hits	66
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA6_MOUSE
NC score	0.040816 (rank : 148)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	154	Target Neighborhood Hits	946	Shared Neighborhood Hits	48
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB4_MOUSE
NC score	0.040446 (rank : 149)	θ value	0.0736092 (rank : 62)
Query Neighborhood Hits	154	Target Neighborhood Hits	1013	Shared Neighborhood Hits	55
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

EPHA6_HUMAN
NC score	0.040220 (rank : 150)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	154	Target Neighborhood Hits	959	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB2_MOUSE
NC score	0.040006 (rank : 151)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	154	Target Neighborhood Hits	982	Shared Neighborhood Hits	46
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB2_HUMAN
NC score	0.040001 (rank : 152)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	154	Target Neighborhood Hits	983	Shared Neighborhood Hits	46
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHA2_MOUSE
NC score	0.038655 (rank : 153)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	154	Target Neighborhood Hits	1020	Shared Neighborhood Hits	59
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EPHA4_MOUSE
NC score	0.038611 (rank : 154)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	154	Target Neighborhood Hits	982	Shared Neighborhood Hits	48
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA7_MOUSE
NC score	0.037341 (rank : 155)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	154	Target Neighborhood Hits	1025	Shared Neighborhood Hits	60
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

EPHA1_HUMAN
NC score	0.037308 (rank : 156)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	154	Target Neighborhood Hits	997	Shared Neighborhood Hits	54
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

EPHA4_HUMAN
NC score	0.037079 (rank : 157)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	154	Target Neighborhood Hits	975	Shared Neighborhood Hits	47
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

TENR_HUMAN
NC score	0.037019 (rank : 158)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	154	Target Neighborhood Hits	526	Shared Neighborhood Hits	66
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

EPHA1_MOUSE
NC score	0.036528 (rank : 159)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	154	Target Neighborhood Hits	958	Shared Neighborhood Hits	55
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

TENR_MOUSE
NC score	0.036275 (rank : 160)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	154	Target Neighborhood Hits	531	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

EPHA8_MOUSE
NC score	0.034884 (rank : 161)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	154	Target Neighborhood Hits	969	Shared Neighborhood Hits	40
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

EPHA8_HUMAN
NC score	0.034881 (rank : 162)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	154	Target Neighborhood Hits	956	Shared Neighborhood Hits	39
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

MUC5B_HUMAN
NC score	0.034625 (rank : 163)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	154	Target Neighborhood Hits	1020	Shared Neighborhood Hits	46
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

EPHA2_HUMAN
NC score	0.034525 (rank : 164)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	154	Target Neighborhood Hits	1021	Shared Neighborhood Hits	52
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA3_HUMAN
NC score	0.034437 (rank : 165)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	154	Target Neighborhood Hits	1005	Shared Neighborhood Hits	54
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHB1_HUMAN
NC score	0.034264 (rank : 166)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	154	Target Neighborhood Hits	988	Shared Neighborhood Hits	53
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

EPHA3_MOUSE
NC score	0.034151 (rank : 167)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	154	Target Neighborhood Hits	1009	Shared Neighborhood Hits	51
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

TNR3_MOUSE
NC score	0.033544 (rank : 168)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	154	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

PGBM_MOUSE
NC score	0.033372 (rank : 169)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	154	Target Neighborhood Hits	1073	Shared Neighborhood Hits	71
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

TNR5_MOUSE
NC score	0.031931 (rank : 170)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	154	Target Neighborhood Hits	131	Shared Neighborhood Hits	34
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

RPB2_HUMAN
NC score	0.030538 (rank : 171)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	154	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P30876, Q8IZ61	Gene names	POLR2B
Domain Architecture
Description	DNA-directed RNA polymerase II 140 kDa polypeptide (EC 2.7.7.6) (RNA polymerase II subunit 2) (RPB2).

RPB2_MOUSE
NC score	0.030532 (rank : 172)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	154	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFI7	Gene names	Polr2b
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase II 140 kDa polypeptide (EC 2.7.7.6) (RNA polymerase II subunit 2) (RPB2).

TNR5_HUMAN
NC score	0.029911 (rank : 173)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	154	Target Neighborhood Hits	102	Shared Neighborhood Hits	25
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

SSPO_MOUSE
NC score	0.029704 (rank : 174)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	154	Target Neighborhood Hits	800	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

LYAM3_HUMAN
NC score	0.026878 (rank : 175)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	154	Target Neighborhood Hits	378	Shared Neighborhood Hits	43
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

VWF_MOUSE
NC score	0.024127 (rank : 176)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	154	Target Neighborhood Hits	381	Shared Neighborhood Hits	41
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ASTN_MOUSE
NC score	0.022151 (rank : 177)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	154	Target Neighborhood Hits	98	Shared Neighborhood Hits	14
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

IGF1R_MOUSE
NC score	0.021344 (rank : 178)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	154	Target Neighborhood Hits	973	Shared Neighborhood Hits	48
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IGF1R_HUMAN
NC score	0.020585 (rank : 179)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	154	Target Neighborhood Hits	977	Shared Neighborhood Hits	43
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

TNR19_MOUSE
NC score	0.020368 (rank : 180)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	154	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1A_MOUSE
NC score	0.018341 (rank : 181)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	154	Target Neighborhood Hits	131	Shared Neighborhood Hits	23
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

UTP20_HUMAN
NC score	0.018263 (rank : 182)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	154	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

IRS2_MOUSE
NC score	0.014891 (rank : 183)	θ value	1.81305 (rank : 101)
Query Neighborhood Hits	154	Target Neighborhood Hits	248	Shared Neighborhood Hits	5
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

PMS2_HUMAN
NC score	0.014670 (rank : 184)	θ value	1.81305 (rank : 102)
Query Neighborhood Hits	154	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

TMCC1_HUMAN
NC score	0.011954 (rank : 185)	θ value	2.36792 (rank : 105)
Query Neighborhood Hits	154	Target Neighborhood Hits	337	Shared Neighborhood Hits	5
SwissProt Accessions	O94876, Q68E06, Q8IXM8	Gene names	TMCC1, KIAA0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

TMCC1_MOUSE
NC score	0.010229 (rank : 186)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	154	Target Neighborhood Hits	315	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

ATP5S_HUMAN
NC score	0.009850 (rank : 187)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	154	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q99766, Q8WWX3	Gene names	ATP5S, ATPW
Domain Architecture	No domain graphic available
Description	ATP synthase subunit s, mitochondrial precursor (ATP synthase coupling factor B) (Mitochondrial ATP synthase regulatory component factor B).

TTPA_HUMAN
NC score	0.009781 (rank : 188)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	154	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P49638, Q71V64	Gene names	TTPA, TPP1
Domain Architecture
Description	Alpha-tocopherol transfer protein (Alpha-TTP).

CASR_HUMAN
NC score	0.009491 (rank : 189)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	154	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

DTNB_MOUSE
NC score	0.007746 (rank : 190)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	154	Target Neighborhood Hits	263	Shared Neighborhood Hits	2
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

LY10_HUMAN
NC score	0.007651 (rank : 191)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	154	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

V2RX_MOUSE
NC score	0.006973 (rank : 192)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	154	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

CAZA3_HUMAN
NC score	0.006250 (rank : 193)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	154	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KX2, Q969J0	Gene names	CAPZA3, CAPAA3, GSG3
Domain Architecture
Description	F-actin capping protein alpha-3 subunit (CapZ alpha-3) (CP-alpha-3) (Germ cell-specific protein 3).

PRG3_MOUSE
NC score	0.005259 (rank : 194)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	154	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

KPB1_MOUSE
NC score	0.004277 (rank : 195)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	154	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P18826	Gene names	Phka1
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit).

SOX13_HUMAN
NC score	0.003679 (rank : 196)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	154	Target Neighborhood Hits	464	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SRGP2_HUMAN
NC score	0.003156 (rank : 197)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	154	Target Neighborhood Hits	331	Shared Neighborhood Hits	4
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
NC score	0.002765 (rank : 198)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	154	Target Neighborhood Hits	324	Shared Neighborhood Hits	3
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

CO2_HUMAN
NC score	0.002319 (rank : 199)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	154	Target Neighborhood Hits	258	Shared Neighborhood Hits	5
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

KLK4_HUMAN
NC score	0.000033 (rank : 200)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	154	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

LRRN1_MOUSE
NC score	0.000003 (rank : 201)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	154	Target Neighborhood Hits	508	Shared Neighborhood Hits	5
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

KV1L_HUMAN
NC score	-0.000992 (rank : 202)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	154	Target Neighborhood Hits	239	Shared Neighborhood Hits	2
SwissProt Accessions	P01604	Gene names
Domain Architecture	No domain graphic available
Description	Ig kappa chain V-I region Kue.

OR2D3_HUMAN
NC score	-0.004723 (rank : 203)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	154	Target Neighborhood Hits	812	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGH3, Q96R51	Gene names	OR2D3
Domain Architecture
Description	Olfactory receptor 2D3.