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Network neighborhood for query Sequence : NLGN1_HUMAN

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NLGN1_HUMAN
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NLGN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN1_MOUSE
θ value	0 (rank : 2)	NC score	0.999777 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	31
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN2_HUMAN
θ value	0 (rank : 3)	NC score	0.994971 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN2_MOUSE
θ value	0 (rank : 4)	NC score	0.995082 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN3_HUMAN
θ value	0 (rank : 5)	NC score	0.997048 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN3_MOUSE
θ value	0 (rank : 6)	NC score	0.996875 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGNX_HUMAN
θ value	0 (rank : 7)	NC score	0.997682 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGNY_HUMAN
θ value	0 (rank : 8)	NC score	0.997552 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

ACES_MOUSE
θ value	3.0217e-80 (rank : 9)	NC score	0.946562 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_HUMAN
θ value	3.94648e-80 (rank : 10)	NC score	0.945467 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

CHLE_HUMAN
θ value	5.33382e-77 (rank : 11)	NC score	0.944050 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

EST1_HUMAN
θ value	1.45253e-74 (rank : 12)	NC score	0.931151 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

CEL_HUMAN
θ value	1.35953e-72 (rank : 13)	NC score	0.720249 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	896	Shared Neighborhood Hits	29
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EST2_HUMAN
θ value	1.35953e-72 (rank : 14)	NC score	0.945595 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

CES3_MOUSE
θ value	2.31901e-72 (rank : 15)	NC score	0.928987 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

CHLE_MOUSE
θ value	2.31901e-72 (rank : 16)	NC score	0.943268 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

EST22_MOUSE
θ value	1.96316e-71 (rank : 17)	NC score	0.930392 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

CEL_MOUSE
θ value	4.37348e-71 (rank : 18)	NC score	0.950822 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EST31_MOUSE
θ value	4.09345e-69 (rank : 19)	NC score	0.945690 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

EST1_MOUSE
θ value	1.19101e-68 (rank : 20)	NC score	0.925877 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

ESTN_MOUSE
θ value	6.11685e-65 (rank : 21)	NC score	0.928006 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

THYG_MOUSE
θ value	4.122e-45 (rank : 22)	NC score	0.804342 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	161	Shared Neighborhood Hits	23
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

THYG_HUMAN
θ value	1.28434e-38 (rank : 23)	NC score	0.785152 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	154	Shared Neighborhood Hits	23
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

AAAD_HUMAN
θ value	0.0252991 (rank : 24)	NC score	0.231323 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AAAD_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.139738 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

CBPD_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.016615 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.016551 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

PCD16_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.002491 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PAXI_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.007604 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VI36, Q3TB62, Q3TZQ6, Q8VI37	Gene names	Pxn
Domain Architecture	No domain graphic available
Description	Paxillin.

SYN1_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.018013 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	419	Shared Neighborhood Hits	7
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

MLL2_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.002993 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	1788	Shared Neighborhood Hits	5
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PAXI_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.006407 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P49023, O14970, O14971, O60360	Gene names	PXN
Domain Architecture
Description	Paxillin.

CK024_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.003174 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	408	Shared Neighborhood Hits	6
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

K0999_HUMAN
θ value	8.99809 (rank : 34)	NC score	-0.003445 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	899	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

K0999_MOUSE
θ value	8.99809 (rank : 35)	NC score	-0.003453 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	931	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

SF3B2_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.017477 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

SYN1_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.014123 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	363	Shared Neighborhood Hits	5
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

SMR3B_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.087746 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

Hits sorted by NC score

NLGN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN1_MOUSE
NC score	0.999777 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	31
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGNX_HUMAN
NC score	0.997682 (rank : 3)	θ value	0 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGNY_HUMAN
NC score	0.997552 (rank : 4)	θ value	0 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

NLGN3_HUMAN
NC score	0.997048 (rank : 5)	θ value	0 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN3_MOUSE
NC score	0.996875 (rank : 6)	θ value	0 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN2_MOUSE
NC score	0.995082 (rank : 7)	θ value	0 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN2_HUMAN
NC score	0.994971 (rank : 8)	θ value	0 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

CEL_MOUSE
NC score	0.950822 (rank : 9)	θ value	4.37348e-71 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

ACES_MOUSE
NC score	0.946562 (rank : 10)	θ value	3.0217e-80 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

EST31_MOUSE
NC score	0.945690 (rank : 11)	θ value	4.09345e-69 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	31	Shared Neighborhood Hits	25
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

EST2_HUMAN
NC score	0.945595 (rank : 12)	θ value	1.35953e-72 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

ACES_HUMAN
NC score	0.945467 (rank : 13)	θ value	3.94648e-80 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

CHLE_HUMAN
NC score	0.944050 (rank : 14)	θ value	5.33382e-77 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	25
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CHLE_MOUSE
NC score	0.943268 (rank : 15)	θ value	2.31901e-72 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

EST1_HUMAN
NC score	0.931151 (rank : 16)	θ value	1.45253e-74 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

EST22_MOUSE
NC score	0.930392 (rank : 17)	θ value	1.96316e-71 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

CES3_MOUSE
NC score	0.928987 (rank : 18)	θ value	2.31901e-72 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

ESTN_MOUSE
NC score	0.928006 (rank : 19)	θ value	6.11685e-65 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

EST1_MOUSE
NC score	0.925877 (rank : 20)	θ value	1.19101e-68 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	25
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

THYG_MOUSE
NC score	0.804342 (rank : 21)	θ value	4.122e-45 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	161	Shared Neighborhood Hits	23
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

THYG_HUMAN
NC score	0.785152 (rank : 22)	θ value	1.28434e-38 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	154	Shared Neighborhood Hits	23
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

CEL_HUMAN
NC score	0.720249 (rank : 23)	θ value	1.35953e-72 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	896	Shared Neighborhood Hits	29
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

AAAD_HUMAN
NC score	0.231323 (rank : 24)	θ value	0.0252991 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AAAD_MOUSE
NC score	0.139738 (rank : 25)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

SMR3B_HUMAN
NC score	0.087746 (rank : 26)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

SYN1_HUMAN
NC score	0.018013 (rank : 27)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	419	Shared Neighborhood Hits	7
SwissProt Accessions	P17600, O75825, Q5H9A9	Gene names	SYN1
Domain Architecture
Description	Synapsin-1 (Synapsin I) (Brain protein 4.1).

SF3B2_HUMAN
NC score	0.017477 (rank : 28)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	Q13435	Gene names	SF3B2, SAP145
Domain Architecture
Description	Splicing factor 3B subunit 2 (Spliceosome-associated protein 145) (SAP 145) (SF3b150) (Pre-mRNA-splicing factor SF3b 145 kDa subunit).

CBPD_HUMAN
NC score	0.016615 (rank : 29)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_MOUSE
NC score	0.016551 (rank : 30)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

SYN1_MOUSE
NC score	0.014123 (rank : 31)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	363	Shared Neighborhood Hits	5
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

PAXI_MOUSE
NC score	0.007604 (rank : 32)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	176	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VI36, Q3TB62, Q3TZQ6, Q8VI37	Gene names	Pxn
Domain Architecture	No domain graphic available
Description	Paxillin.

PAXI_HUMAN
NC score	0.006407 (rank : 33)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P49023, O14970, O14971, O60360	Gene names	PXN
Domain Architecture
Description	Paxillin.

CK024_HUMAN
NC score	0.003174 (rank : 34)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	408	Shared Neighborhood Hits	6
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

MLL2_HUMAN
NC score	0.002993 (rank : 35)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	1788	Shared Neighborhood Hits	5
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PCD16_HUMAN
NC score	0.002491 (rank : 36)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	245	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

K0999_HUMAN
NC score	-0.003445 (rank : 37)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	899	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

K0999_MOUSE
NC score	-0.003453 (rank : 38)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	931	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).