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Network neighborhood for query Sequence : CHLE_MOUSE

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CHLE_MOUSE
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CHLE_HUMAN
θ value	0 (rank : 1)	NC score	0.998874 (rank : 2)
Query Neighborhood Hits	32	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CHLE_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	32	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

ACES_MOUSE
θ value	3.24166e-183 (rank : 3)	NC score	0.994579 (rank : 3)
Query Neighborhood Hits	32	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_HUMAN
θ value	4.23373e-183 (rank : 4)	NC score	0.994287 (rank : 4)
Query Neighborhood Hits	32	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

NLGNX_HUMAN
θ value	1.00358e-83 (rank : 5)	NC score	0.946054 (rank : 11)
Query Neighborhood Hits	32	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGNY_HUMAN
θ value	2.91998e-83 (rank : 6)	NC score	0.946250 (rank : 10)
Query Neighborhood Hits	32	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

NLGN2_MOUSE
θ value	1.89267e-82 (rank : 7)	NC score	0.947979 (rank : 8)
Query Neighborhood Hits	32	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN2_HUMAN
θ value	2.47191e-82 (rank : 8)	NC score	0.947873 (rank : 9)
Query Neighborhood Hits	32	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGN3_MOUSE
θ value	2.1655e-78 (rank : 9)	NC score	0.945043 (rank : 12)
Query Neighborhood Hits	32	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN3_HUMAN
θ value	1.5519e-76 (rank : 10)	NC score	0.944277 (rank : 13)
Query Neighborhood Hits	32	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

EST2_HUMAN
θ value	1.04096e-72 (rank : 11)	NC score	0.961137 (rank : 6)
Query Neighborhood Hits	32	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

NLGN1_MOUSE
θ value	1.35953e-72 (rank : 12)	NC score	0.943191 (rank : 16)
Query Neighborhood Hits	32	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN1_HUMAN
θ value	2.31901e-72 (rank : 13)	NC score	0.943268 (rank : 15)
Query Neighborhood Hits	32	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

CEL_MOUSE
θ value	1.83746e-69 (rank : 14)	NC score	0.963530 (rank : 5)
Query Neighborhood Hits	32	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CEL_HUMAN
θ value	1.2325e-65 (rank : 15)	NC score	0.728808 (rank : 23)
Query Neighborhood Hits	32	Target Neighborhood Hits	896	Shared Neighborhood Hits	25
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EST22_MOUSE
θ value	3.03575e-64 (rank : 16)	NC score	0.943890 (rank : 14)
Query Neighborhood Hits	32	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

CES3_MOUSE
θ value	1.66577e-62 (rank : 17)	NC score	0.941958 (rank : 18)
Query Neighborhood Hits	32	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

ESTN_MOUSE
θ value	1.07972e-61 (rank : 18)	NC score	0.942713 (rank : 17)
Query Neighborhood Hits	32	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

EST1_HUMAN
θ value	2.40537e-61 (rank : 19)	NC score	0.941942 (rank : 19)
Query Neighborhood Hits	32	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

THYG_MOUSE
θ value	2.94036e-59 (rank : 20)	NC score	0.843386 (rank : 21)
Query Neighborhood Hits	32	Target Neighborhood Hits	161	Shared Neighborhood Hits	23
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

THYG_HUMAN
θ value	2.48917e-58 (rank : 21)	NC score	0.831303 (rank : 22)
Query Neighborhood Hits	32	Target Neighborhood Hits	154	Shared Neighborhood Hits	23
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

EST31_MOUSE
θ value	1.78386e-56 (rank : 22)	NC score	0.953811 (rank : 7)
Query Neighborhood Hits	32	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

EST1_MOUSE
θ value	5.19021e-56 (rank : 23)	NC score	0.939099 (rank : 20)
Query Neighborhood Hits	32	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

AAAD_HUMAN
θ value	9.29e-05 (rank : 24)	NC score	0.281899 (rank : 24)
Query Neighborhood Hits	32	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

LIPS_HUMAN
θ value	0.21417 (rank : 25)	NC score	0.055413 (rank : 27)
Query Neighborhood Hits	32	Target Neighborhood Hits	314	Shared Neighborhood Hits	6
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

LIPS_MOUSE
θ value	1.06291 (rank : 26)	NC score	0.054858 (rank : 28)
Query Neighborhood Hits	32	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	P54310, P97866, Q3TE34, Q6GU16	Gene names	Lipe
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

TXD11_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.010604 (rank : 29)
Query Neighborhood Hits	32	Target Neighborhood Hits	402	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

FBW1A_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.000282 (rank : 33)
Query Neighborhood Hits	32	Target Neighborhood Hits	329	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

LRSM1_HUMAN
θ value	6.88961 (rank : 29)	NC score	-0.000160 (rank : 34)
Query Neighborhood Hits	32	Target Neighborhood Hits	1078	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

CO3A1_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.007854 (rank : 30)
Query Neighborhood Hits	32	Target Neighborhood Hits	452	Shared Neighborhood Hits	3
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

LRSM1_MOUSE
θ value	8.99809 (rank : 31)	NC score	0.000487 (rank : 32)
Query Neighborhood Hits	32	Target Neighborhood Hits	874	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

ZDHC6_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.003166 (rank : 31)
Query Neighborhood Hits	32	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CPV7, Q3U3I8, Q3UT70, Q544H1	Gene names	Zdhhc6
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC6 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) (H4 homolog).

AAAD_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.160094 (rank : 25)
Query Neighborhood Hits	32	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

SMR3B_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.073897 (rank : 26)
Query Neighborhood Hits	32	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

Hits sorted by NC score

CHLE_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	32	Target Neighborhood Hits	32	Shared Neighborhood Hits	32
SwissProt Accessions	Q03311	Gene names	Bche
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

CHLE_HUMAN
NC score	0.998874 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	32	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	P06276	Gene names	BCHE, CHE1
Domain Architecture
Description	Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase).

ACES_MOUSE
NC score	0.994579 (rank : 3)	θ value	3.24166e-183 (rank : 3)
Query Neighborhood Hits	32	Target Neighborhood Hits	29	Shared Neighborhood Hits	25
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_HUMAN
NC score	0.994287 (rank : 4)	θ value	4.23373e-183 (rank : 4)
Query Neighborhood Hits	32	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

CEL_MOUSE
NC score	0.963530 (rank : 5)	θ value	1.83746e-69 (rank : 14)
Query Neighborhood Hits	32	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q64285	Gene names	Cel, Lip1
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

EST2_HUMAN
NC score	0.961137 (rank : 6)	θ value	1.04096e-72 (rank : 11)
Query Neighborhood Hits	32	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	O00748, Q16859, Q5MAB8, Q7Z366, Q8IUP4, Q8TCP8	Gene names	CES2, ICE
Domain Architecture
Description	Carboxylesterase 2 precursor (EC 3.1.1.1) (CE-2) (hCE-2).

EST31_MOUSE
NC score	0.953811 (rank : 7)	θ value	1.78386e-56 (rank : 22)
Query Neighborhood Hits	32	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q63880	Gene names	Es31
Domain Architecture
Description	Liver carboxylesterase 31 precursor (EC 3.1.1.1) (ES-Male) (Esterase- 31).

NLGN2_MOUSE
NC score	0.947979 (rank : 8)	θ value	1.89267e-82 (rank : 7)
Query Neighborhood Hits	32	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q69ZK9, Q5F288	Gene names	Nlgn2, Kiaa1366
Domain Architecture	No domain graphic available
Description	Neuroligin-2 precursor.

NLGN2_HUMAN
NC score	0.947873 (rank : 9)	θ value	2.47191e-82 (rank : 8)
Query Neighborhood Hits	32	Target Neighborhood Hits	55	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ4, Q9P2I1	Gene names	NLGN2, KIAA1366
Domain Architecture
Description	Neuroligin-2 precursor.

NLGNY_HUMAN
NC score	0.946250 (rank : 10)	θ value	2.91998e-83 (rank : 6)
Query Neighborhood Hits	32	Target Neighborhood Hits	37	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFZ3, Q7Z3T5, Q9Y2F8	Gene names	NLGN4Y, KIAA0951
Domain Architecture
Description	Neuroligin-4, Y-linked precursor (Neuroligin Y).

NLGNX_HUMAN
NC score	0.946054 (rank : 11)	θ value	1.00358e-83 (rank : 5)
Query Neighborhood Hits	32	Target Neighborhood Hits	35	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N0W4, Q6UX10, Q9ULG0	Gene names	NLGN4X, KIAA1260, NLGN4
Domain Architecture
Description	Neuroligin-4, X-linked precursor (Neuroligin X) (HNLX).

NLGN3_MOUSE
NC score	0.945043 (rank : 12)	θ value	2.1655e-78 (rank : 9)
Query Neighborhood Hits	32	Target Neighborhood Hits	48	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BYM5, Q8BXR4	Gene names	Nlgn3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

NLGN3_HUMAN
NC score	0.944277 (rank : 13)	θ value	1.5519e-76 (rank : 10)
Query Neighborhood Hits	32	Target Neighborhood Hits	45	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZ94, Q8NCD0, Q9NZ95, Q9NZ96, Q9NZ97, Q9P248	Gene names	NLGN3, KIAA1480, NL3
Domain Architecture
Description	Neuroligin-3 precursor (Gliotactin homolog).

EST22_MOUSE
NC score	0.943890 (rank : 14)	θ value	3.03575e-64 (rank : 16)
Query Neighborhood Hits	32	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q64176	Gene names	Es22
Domain Architecture
Description	Liver carboxylesterase 22 precursor (EC 3.1.1.1) (Egasyn) (Esterase- 22) (Es-22).

NLGN1_HUMAN
NC score	0.943268 (rank : 15)	θ value	2.31901e-72 (rank : 13)
Query Neighborhood Hits	32	Target Neighborhood Hits	37	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N2Q7, Q9UPT2	Gene names	NLGN1, KIAA1070
Domain Architecture
Description	Neuroligin-1 precursor.

NLGN1_MOUSE
NC score	0.943191 (rank : 16)	θ value	1.35953e-72 (rank : 12)
Query Neighborhood Hits	32	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q99K10	Gene names	Nlgn1, Kiaa1070
Domain Architecture
Description	Neuroligin-1 precursor.

ESTN_MOUSE
NC score	0.942713 (rank : 17)	θ value	1.07972e-61 (rank : 18)
Query Neighborhood Hits	32	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	P23953, O54936, P11374, Q8K125	Gene names	Es1
Domain Architecture
Description	Liver carboxylesterase N precursor (EC 3.1.1.1) (PES-N) (Lung surfactant convertase).

CES3_MOUSE
NC score	0.941958 (rank : 18)	θ value	1.66577e-62 (rank : 17)
Query Neighborhood Hits	32	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VCT4, Q91ZV9, Q924V8, Q9ULY1	Gene names	Ces3, Ces1
Domain Architecture	No domain graphic available
Description	Carboxylesterase 3 precursor (EC 3.1.1.1) (Triacylglycerol hydrolase) (TGH).

EST1_HUMAN
NC score	0.941942 (rank : 19)	θ value	2.40537e-61 (rank : 19)
Query Neighborhood Hits	32	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	P23141, Q00015, Q13657, Q14062, Q16737, Q16788, Q86UK2, Q96EE8, Q9UK77, Q9ULY2	Gene names	CES1, CES2, SES1
Domain Architecture
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ACAT) (Monocyte/macrophage serine esterase) (HMSE) (Serine esterase 1) (Brain carboxylesterase hBr1) (Triacylglycerol hydrolase) (TGH) (Egasyn).

EST1_MOUSE
NC score	0.939099 (rank : 20)	θ value	5.19021e-56 (rank : 23)
Query Neighborhood Hits	32	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VCC2, O55136	Gene names	Ces1
Domain Architecture	No domain graphic available
Description	Liver carboxylesterase 1 precursor (EC 3.1.1.1) (Acyl coenzyme A:cholesterol acyltransferase) (ES-x).

THYG_MOUSE
NC score	0.843386 (rank : 21)	θ value	2.94036e-59 (rank : 20)
Query Neighborhood Hits	32	Target Neighborhood Hits	161	Shared Neighborhood Hits	23
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

THYG_HUMAN
NC score	0.831303 (rank : 22)	θ value	2.48917e-58 (rank : 21)
Query Neighborhood Hits	32	Target Neighborhood Hits	154	Shared Neighborhood Hits	23
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

CEL_HUMAN
NC score	0.728808 (rank : 23)	θ value	1.2325e-65 (rank : 15)
Query Neighborhood Hits	32	Target Neighborhood Hits	896	Shared Neighborhood Hits	25
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

AAAD_HUMAN
NC score	0.281899 (rank : 24)	θ value	9.29e-05 (rank : 24)
Query Neighborhood Hits	32	Target Neighborhood Hits	22	Shared Neighborhood Hits	18
SwissProt Accessions	P22760, Q8N1A9	Gene names	AADAC, DAC
Domain Architecture
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

AAAD_MOUSE
NC score	0.160094 (rank : 25)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	32	Target Neighborhood Hits	24	Shared Neighborhood Hits	17
SwissProt Accessions	Q99PG0, Q8VCF2	Gene names	Aadac, Aada
Domain Architecture	No domain graphic available
Description	Arylacetamide deacetylase (EC 3.1.1.-) (AADAC).

SMR3B_HUMAN
NC score	0.073897 (rank : 26)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	32	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P02814, Q9UBN0, Q9UCT0	Gene names	SMR3B, PBII, PROL3
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog B precursor (Proline-rich protein 3) (Proline-rich peptide P-B) [Contains: Peptide P-A; Peptide D1A].

LIPS_HUMAN
NC score	0.055413 (rank : 27)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	32	Target Neighborhood Hits	314	Shared Neighborhood Hits	6
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

LIPS_MOUSE
NC score	0.054858 (rank : 28)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	32	Target Neighborhood Hits	17	Shared Neighborhood Hits	5
SwissProt Accessions	P54310, P97866, Q3TE34, Q6GU16	Gene names	Lipe
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

TXD11_HUMAN
NC score	0.010604 (rank : 29)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	32	Target Neighborhood Hits	402	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

CO3A1_HUMAN
NC score	0.007854 (rank : 30)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	32	Target Neighborhood Hits	452	Shared Neighborhood Hits	3
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

ZDHC6_MOUSE
NC score	0.003166 (rank : 31)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	32	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CPV7, Q3U3I8, Q3UT70, Q544H1	Gene names	Zdhhc6
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC6 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) (H4 homolog).

LRSM1_MOUSE
NC score	0.000487 (rank : 32)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	32	Target Neighborhood Hits	874	Shared Neighborhood Hits	3
SwissProt Accessions	Q80ZI6	Gene names	Lrsam1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase).

FBW1A_HUMAN
NC score	0.000282 (rank : 33)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	32	Target Neighborhood Hits	329	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y297, Q9Y213	Gene names	BTRC, BTRCP, FBW1A, FBXW1A
Domain Architecture
Description	F-box/WD repeat protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit).

LRSM1_HUMAN
NC score	-0.000160 (rank : 34)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	32	Target Neighborhood Hits	1078	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).