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Network neighborhood for query Sequence : HG2A_HUMAN

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HG2A_HUMAN
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HG2A_HUMAN
θ value	1.40939e-178 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

HG2A_MOUSE
θ value	2.52267e-127 (rank : 2)	NC score	0.993009 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

NID2_HUMAN
θ value	2.69671e-12 (rank : 3)	NC score	0.297855 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	456	Shared Neighborhood Hits	31
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID1_HUMAN
θ value	2.98157e-11 (rank : 4)	NC score	0.290649 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	329	Shared Neighborhood Hits	31
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_MOUSE
θ value	7.34386e-10 (rank : 5)	NC score	0.290761 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	338	Shared Neighborhood Hits	31
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

TICN1_MOUSE
θ value	1.63604e-09 (rank : 6)	NC score	0.578253 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	79	Shared Neighborhood Hits	31
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_HUMAN
θ value	3.64472e-09 (rank : 7)	NC score	0.580901 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN3_HUMAN
θ value	3.64472e-09 (rank : 8)	NC score	0.563936 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN3_MOUSE
θ value	1.38499e-08 (rank : 9)	NC score	0.555450 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

NID1_MOUSE
θ value	2.36244e-08 (rank : 10)	NC score	0.278163 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	335	Shared Neighborhood Hits	30
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TICN2_HUMAN
θ value	8.97725e-08 (rank : 11)	NC score	0.564449 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_MOUSE
θ value	1.53129e-07 (rank : 12)	NC score	0.558262 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

SMOC2_HUMAN
θ value	1.09739e-05 (rank : 13)	NC score	0.492464 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC2_MOUSE
θ value	1.09739e-05 (rank : 14)	NC score	0.492474 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

THYG_MOUSE
θ value	2.44474e-05 (rank : 15)	NC score	0.289598 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	161	Shared Neighborhood Hits	31
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

THYG_HUMAN
θ value	9.29e-05 (rank : 16)	NC score	0.293543 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	154	Shared Neighborhood Hits	31
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

SMOC1_HUMAN
θ value	0.000121331 (rank : 17)	NC score	0.475985 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
θ value	0.000270298 (rank : 18)	NC score	0.467313 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	74	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

IBP1_HUMAN
θ value	0.00134147 (rank : 19)	NC score	0.377725 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP2_MOUSE
θ value	0.00228821 (rank : 20)	NC score	0.358256 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP1_MOUSE
θ value	0.00298849 (rank : 21)	NC score	0.346452 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	97	Shared Neighborhood Hits	29
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP2_HUMAN
θ value	0.0148317 (rank : 22)	NC score	0.336187 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP4_HUMAN
θ value	0.0252991 (rank : 23)	NC score	0.360652 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	52	Shared Neighborhood Hits	31
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
θ value	0.0252991 (rank : 24)	NC score	0.364324 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP6_MOUSE
θ value	0.125558 (rank : 25)	NC score	0.347354 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP3_HUMAN
θ value	0.279714 (rank : 26)	NC score	0.354981 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

TACD1_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.286393 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

IBP3_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.341289 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP5_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.309373 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP6_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.349898 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

TIF1G_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.015882 (rank : 74)
Query Neighborhood Hits	36	Target Neighborhood Hits	410	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

IBP5_MOUSE
θ value	3.0926 (rank : 32)	NC score	0.305742 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

PCD12_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.003747 (rank : 76)
Query Neighborhood Hits	36	Target Neighborhood Hits	203	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

PRR11_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.024148 (rank : 73)
Query Neighborhood Hits	36	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q96HE9, Q9NUZ7, Q9NXE9	Gene names	PRR11
Domain Architecture	No domain graphic available
Description	Proline-rich protein 11.

UTRO_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.003134 (rank : 77)
Query Neighborhood Hits	36	Target Neighborhood Hits	960	Shared Neighborhood Hits	2
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

TIF1G_MOUSE
θ value	8.99809 (rank : 36)	NC score	0.012417 (rank : 75)
Query Neighborhood Hits	36	Target Neighborhood Hits	498	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

AGRIN_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.060487 (rank : 58)
Query Neighborhood Hits	36	Target Neighborhood Hits	582	Shared Neighborhood Hits	14
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CREL1_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.052290 (rank : 69)
Query Neighborhood Hits	36	Target Neighborhood Hits	441	Shared Neighborhood Hits	6
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.050648 (rank : 72)
Query Neighborhood Hits	36	Target Neighborhood Hits	524	Shared Neighborhood Hits	5
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGF_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.066487 (rank : 47)
Query Neighborhood Hits	36	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EGF_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.063832 (rank : 54)
Query Neighborhood Hits	36	Target Neighborhood Hits	358	Shared Neighborhood Hits	4
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FBLN3_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.051132 (rank : 71)
Query Neighborhood Hits	36	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FSTL1_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.084937 (rank : 39)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.086204 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	74	Shared Neighborhood Hits	10
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL3_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.071112 (rank : 45)
Query Neighborhood Hits	36	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.067081 (rank : 46)
Query Neighborhood Hits	36	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.087580 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	129	Shared Neighborhood Hits	10
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.084228 (rank : 40)
Query Neighborhood Hits	36	Target Neighborhood Hits	146	Shared Neighborhood Hits	10
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

KAZD1_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.065430 (rank : 50)
Query Neighborhood Hits	36	Target Neighborhood Hits	248	Shared Neighborhood Hits	20
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.052791 (rank : 68)
Query Neighborhood Hits	36	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

LDLR_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.057983 (rank : 60)
Query Neighborhood Hits	36	Target Neighborhood Hits	375	Shared Neighborhood Hits	4
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.060457 (rank : 59)
Query Neighborhood Hits	36	Target Neighborhood Hits	382	Shared Neighborhood Hits	4
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP4_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.063254 (rank : 55)
Query Neighborhood Hits	36	Target Neighborhood Hits	355	Shared Neighborhood Hits	4
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.062912 (rank : 56)
Query Neighborhood Hits	36	Target Neighborhood Hits	351	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.076545 (rank : 41)
Query Neighborhood Hits	36	Target Neighborhood Hits	224	Shared Neighborhood Hits	4
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.076256 (rank : 42)
Query Neighborhood Hits	36	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.075521 (rank : 43)
Query Neighborhood Hits	36	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.075419 (rank : 44)
Query Neighborhood Hits	36	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP8_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.063858 (rank : 53)
Query Neighborhood Hits	36	Target Neighborhood Hits	346	Shared Neighborhood Hits	4
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP8_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.061050 (rank : 57)
Query Neighborhood Hits	36	Target Neighborhood Hits	385	Shared Neighborhood Hits	4
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SORL_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.053999 (rank : 64)
Query Neighborhood Hits	36	Target Neighborhood Hits	440	Shared Neighborhood Hits	4
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.053480 (rank : 65)
Query Neighborhood Hits	36	Target Neighborhood Hits	439	Shared Neighborhood Hits	4
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SPRC_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.133992 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.129207 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRL1_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.117384 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SPRL1_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.107355 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	403	Shared Neighborhood Hits	10
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

STAB2_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.051183 (rank : 70)
Query Neighborhood Hits	36	Target Neighborhood Hits	528	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SUSD1_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.052861 (rank : 67)
Query Neighborhood Hits	36	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TACD2_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.199467 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

TECTA_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.064633 (rank : 51)
Query Neighborhood Hits	36	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.063880 (rank : 52)
Query Neighborhood Hits	36	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.066089 (rank : 49)
Query Neighborhood Hits	36	Target Neighborhood Hits	211	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.066173 (rank : 48)
Query Neighborhood Hits	36	Target Neighborhood Hits	214	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

UROM_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.053470 (rank : 66)
Query Neighborhood Hits	36	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.054398 (rank : 63)
Query Neighborhood Hits	36	Target Neighborhood Hits	276	Shared Neighborhood Hits	4
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VLDLR_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.056814 (rank : 62)
Query Neighborhood Hits	36	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.057221 (rank : 61)
Query Neighborhood Hits	36	Target Neighborhood Hits	360	Shared Neighborhood Hits	4
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

Hits sorted by NC score

HG2A_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.40939e-178 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

HG2A_MOUSE
NC score	0.993009 (rank : 2)	θ value	2.52267e-127 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	31
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

TICN1_HUMAN
NC score	0.580901 (rank : 3)	θ value	3.64472e-09 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_MOUSE
NC score	0.578253 (rank : 4)	θ value	1.63604e-09 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	79	Shared Neighborhood Hits	31
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN2_HUMAN
NC score	0.564449 (rank : 5)	θ value	8.97725e-08 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN3_HUMAN
NC score	0.563936 (rank : 6)	θ value	3.64472e-09 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

TICN2_MOUSE
NC score	0.558262 (rank : 7)	θ value	1.53129e-07 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN3_MOUSE
NC score	0.555450 (rank : 8)	θ value	1.38499e-08 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	83	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

SMOC2_MOUSE
NC score	0.492474 (rank : 9)	θ value	1.09739e-05 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC2_HUMAN
NC score	0.492464 (rank : 10)	θ value	1.09739e-05 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

SMOC1_HUMAN
NC score	0.475985 (rank : 11)	θ value	0.000121331 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	81	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
NC score	0.467313 (rank : 12)	θ value	0.000270298 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	74	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

IBP1_HUMAN
NC score	0.377725 (rank : 13)	θ value	0.00134147 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP4_MOUSE
NC score	0.364324 (rank : 14)	θ value	0.0252991 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_HUMAN
NC score	0.360652 (rank : 15)	θ value	0.0252991 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	52	Shared Neighborhood Hits	31
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP2_MOUSE
NC score	0.358256 (rank : 16)	θ value	0.00228821 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP3_HUMAN
NC score	0.354981 (rank : 17)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	67	Shared Neighborhood Hits	31
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP6_HUMAN
NC score	0.349898 (rank : 18)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	55	Shared Neighborhood Hits	31
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP6_MOUSE
NC score	0.347354 (rank : 19)	θ value	0.125558 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	53	Shared Neighborhood Hits	31
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP1_MOUSE
NC score	0.346452 (rank : 20)	θ value	0.00298849 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	97	Shared Neighborhood Hits	29
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP3_MOUSE
NC score	0.341289 (rank : 21)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP2_HUMAN
NC score	0.336187 (rank : 22)	θ value	0.0148317 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP5_HUMAN
NC score	0.309373 (rank : 23)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
NC score	0.305742 (rank : 24)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	31
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

NID2_HUMAN
NC score	0.297855 (rank : 25)	θ value	2.69671e-12 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	456	Shared Neighborhood Hits	31
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

THYG_HUMAN
NC score	0.293543 (rank : 26)	θ value	9.29e-05 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	154	Shared Neighborhood Hits	31
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

NID2_MOUSE
NC score	0.290761 (rank : 27)	θ value	7.34386e-10 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	338	Shared Neighborhood Hits	31
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NID1_HUMAN
NC score	0.290649 (rank : 28)	θ value	2.98157e-11 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	329	Shared Neighborhood Hits	31
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

THYG_MOUSE
NC score	0.289598 (rank : 29)	θ value	2.44474e-05 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	161	Shared Neighborhood Hits	31
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TACD1_HUMAN
NC score	0.286393 (rank : 30)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

NID1_MOUSE
NC score	0.278163 (rank : 31)	θ value	2.36244e-08 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	335	Shared Neighborhood Hits	30
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TACD2_HUMAN
NC score	0.199467 (rank : 32)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	36	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

SPRC_HUMAN
NC score	0.133992 (rank : 33)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	36	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
NC score	0.129207 (rank : 34)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRL1_HUMAN
NC score	0.117384 (rank : 35)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	36	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

SPRL1_MOUSE
NC score	0.107355 (rank : 36)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	36	Target Neighborhood Hits	403	Shared Neighborhood Hits	10
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

FST_HUMAN
NC score	0.087580 (rank : 37)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	36	Target Neighborhood Hits	129	Shared Neighborhood Hits	10
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FSTL1_MOUSE
NC score	0.086204 (rank : 38)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	36	Target Neighborhood Hits	74	Shared Neighborhood Hits	10
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL1_HUMAN
NC score	0.084937 (rank : 39)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	36	Target Neighborhood Hits	68	Shared Neighborhood Hits	10
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FST_MOUSE
NC score	0.084228 (rank : 40)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	36	Target Neighborhood Hits	146	Shared Neighborhood Hits	10
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

LRP5_HUMAN
NC score	0.076545 (rank : 41)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	36	Target Neighborhood Hits	224	Shared Neighborhood Hits	4
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
NC score	0.076256 (rank : 42)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	36	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
NC score	0.075521 (rank : 43)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	36	Target Neighborhood Hits	235	Shared Neighborhood Hits	4
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
NC score	0.075419 (rank : 44)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	36	Target Neighborhood Hits	232	Shared Neighborhood Hits	4
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

FSTL3_HUMAN
NC score	0.071112 (rank : 45)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	36	Target Neighborhood Hits	162	Shared Neighborhood Hits	12
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
NC score	0.067081 (rank : 46)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	36	Target Neighborhood Hits	152	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

EGF_HUMAN
NC score	0.066487 (rank : 47)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	36	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

TEFF2_MOUSE
NC score	0.066173 (rank : 48)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	36	Target Neighborhood Hits	214	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.066089 (rank : 49)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	36	Target Neighborhood Hits	211	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

KAZD1_HUMAN
NC score	0.065430 (rank : 50)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	36	Target Neighborhood Hits	248	Shared Neighborhood Hits	20
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

TECTA_HUMAN
NC score	0.064633 (rank : 51)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	36	Target Neighborhood Hits	239	Shared Neighborhood Hits	4
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
NC score	0.063880 (rank : 52)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	36	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

LRP8_HUMAN
NC score	0.063858 (rank : 53)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	36	Target Neighborhood Hits	346	Shared Neighborhood Hits	4
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

EGF_MOUSE
NC score	0.063832 (rank : 54)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	36	Target Neighborhood Hits	358	Shared Neighborhood Hits	4
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

LRP4_HUMAN
NC score	0.063254 (rank : 55)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	36	Target Neighborhood Hits	355	Shared Neighborhood Hits	4
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
NC score	0.062912 (rank : 56)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	36	Target Neighborhood Hits	351	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP8_MOUSE
NC score	0.061050 (rank : 57)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	36	Target Neighborhood Hits	385	Shared Neighborhood Hits	4
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

AGRIN_HUMAN
NC score	0.060487 (rank : 58)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	582	Shared Neighborhood Hits	14
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

LDLR_MOUSE
NC score	0.060457 (rank : 59)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	36	Target Neighborhood Hits	382	Shared Neighborhood Hits	4
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_HUMAN
NC score	0.057983 (rank : 60)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	36	Target Neighborhood Hits	375	Shared Neighborhood Hits	4
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

VLDLR_MOUSE
NC score	0.057221 (rank : 61)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	36	Target Neighborhood Hits	360	Shared Neighborhood Hits	4
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_HUMAN
NC score	0.056814 (rank : 62)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	36	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

UROM_MOUSE
NC score	0.054398 (rank : 63)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	36	Target Neighborhood Hits	276	Shared Neighborhood Hits	4
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

SORL_HUMAN
NC score	0.053999 (rank : 64)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	36	Target Neighborhood Hits	440	Shared Neighborhood Hits	4
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
NC score	0.053480 (rank : 65)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	36	Target Neighborhood Hits	439	Shared Neighborhood Hits	4
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

UROM_HUMAN
NC score	0.053470 (rank : 66)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	36	Target Neighborhood Hits	284	Shared Neighborhood Hits	4
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

SUSD1_HUMAN
NC score	0.052861 (rank : 67)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	36	Target Neighborhood Hits	285	Shared Neighborhood Hits	4
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

KAZD1_MOUSE
NC score	0.052791 (rank : 68)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	36	Target Neighborhood Hits	281	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

CREL1_HUMAN
NC score	0.052290 (rank : 69)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	441	Shared Neighborhood Hits	6
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

STAB2_MOUSE
NC score	0.051183 (rank : 70)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	36	Target Neighborhood Hits	528	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

FBLN3_MOUSE
NC score	0.051132 (rank : 71)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	36	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

CREL1_MOUSE
NC score	0.050648 (rank : 72)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	36	Target Neighborhood Hits	524	Shared Neighborhood Hits	5
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

PRR11_HUMAN
NC score	0.024148 (rank : 73)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q96HE9, Q9NUZ7, Q9NXE9	Gene names	PRR11
Domain Architecture	No domain graphic available
Description	Proline-rich protein 11.

TIF1G_HUMAN
NC score	0.015882 (rank : 74)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	410	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.012417 (rank : 75)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	498	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

PCD12_HUMAN
NC score	0.003747 (rank : 76)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	203	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NPG4, Q6UXB6, Q96KB8, Q9H7Y6, Q9H8E0	Gene names	PCDH12
Domain Architecture
Description	Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).

UTRO_HUMAN
NC score	0.003134 (rank : 77)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	960	Shared Neighborhood Hits	2
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).